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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for NKX2-3

Z-value: 0.53

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Transcription factors associated with NKX2-3

Gene Symbol Gene ID Gene Info
ENSG00000119919.11 NKX2-3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NKX2-3hg38_v1_chr10_+_99532927_995329530.048.6e-01Click!

Activity profile of NKX2-3 motif

Sorted Z-values of NKX2-3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of NKX2-3

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr11_-_102798148 1.38 ENST00000315274.7
matrix metallopeptidase 1
chr11_+_35189869 1.31 ENST00000525688.5
ENST00000278385.10
ENST00000533222.5
CD44 molecule (Indian blood group)
chr10_-_48605032 1.26 ENST00000249601.9
Rho GTPase activating protein 22
chr2_-_162318129 0.94 ENST00000679938.1
interferon induced with helicase C domain 1
chr1_-_89022827 0.79 ENST00000370481.9
ENST00000564665.1
guanylate binding protein 3
chr1_+_65147657 0.75 ENST00000546702.5
adenylate kinase 4
chr14_-_91253925 0.72 ENST00000531499.2
G protein-coupled receptor 68
chr11_+_35189964 0.71 ENST00000524922.1
CD44 molecule (Indian blood group)
chr7_-_80919017 0.57 ENST00000265361.8
semaphorin 3C
chr1_+_65147514 0.52 ENST00000545314.5
adenylate kinase 4
chr3_+_149474688 0.51 ENST00000305354.5
ENST00000465758.1
transmembrane 4 L six family member 4
chr3_+_155083523 0.47 ENST00000680057.1
membrane metalloendopeptidase
chr10_+_99659430 0.46 ENST00000370489.5
ectonucleoside triphosphate diphosphohydrolase 7
chr4_+_88378842 0.46 ENST00000264346.12
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chr6_-_11779606 0.44 ENST00000506810.1
androgen dependent TFPI regulating protein
chr4_+_87832917 0.44 ENST00000395102.8
ENST00000497649.6
ENST00000540395.1
ENST00000560249.5
ENST00000511670.5
ENST00000361056.3
matrix extracellular phosphoglycoprotein
chr3_-_151203201 0.44 ENST00000480322.1
ENST00000309180.6
G protein-coupled receptor 171
chr18_+_58362467 0.43 ENST00000675101.1
NEDD4 like E3 ubiquitin protein ligase
chr18_-_36122110 0.42 ENST00000586829.1
solute carrier family 39 member 6
chr10_+_16436996 0.41 ENST00000535784.7
phosphotriesterase related
chr16_+_56935371 0.41 ENST00000568358.1
homocysteine inducible ER protein with ubiquitin like domain 1
chr10_+_16436943 0.40 ENST00000423462.6
ENST00000378000.5
phosphotriesterase related
chr12_-_122703346 0.40 ENST00000328880.6
hydroxycarboxylic acid receptor 2
chr4_+_94974984 0.40 ENST00000672698.1
bone morphogenetic protein receptor type 1B
chr11_+_94543894 0.39 ENST00000358752.4
fucosyltransferase 4
chr3_+_155083889 0.38 ENST00000680282.1
membrane metalloendopeptidase
chr5_+_157266079 0.37 ENST00000616178.4
ENST00000522463.5
ENST00000435847.6
ENST00000620254.5
ENST00000521420.5
ENST00000617629.4
cytoplasmic FMR1 interacting protein 2
chr6_+_31587002 0.36 ENST00000376090.6
leukocyte specific transcript 1
chr2_-_2326378 0.33 ENST00000647618.1
myelin transcription factor 1 like
chr6_+_82363199 0.33 ENST00000535040.4
trophoblast glycoprotein
chr6_+_69232406 0.32 ENST00000238918.12
adhesion G protein-coupled receptor B3
chr19_-_10231293 0.30 ENST00000646641.1
sphingosine-1-phosphate receptor 2
chr18_+_34593312 0.29 ENST00000591816.6
ENST00000588125.5
ENST00000684610.1
ENST00000683705.1
ENST00000598334.5
ENST00000588684.5
ENST00000554864.7
ENST00000399121.9
ENST00000595022.5
dystrobrevin alpha
chr18_-_28036585 0.29 ENST00000399380.7
cadherin 2
chr9_+_128203371 0.29 ENST00000475805.5
ENST00000372923.8
ENST00000341179.11
ENST00000393594.7
dynamin 1
chr22_+_38057371 0.29 ENST00000437453.5
ENST00000356976.8
protein interacting with PRKCA 1
chr13_-_29595670 0.28 ENST00000380752.10
solute carrier family 7 member 1
chr8_+_103298433 0.28 ENST00000522566.5
frizzled class receptor 6
chr8_-_27478851 0.28 ENST00000240132.7
cholinergic receptor nicotinic alpha 2 subunit
chr12_-_122716790 0.27 ENST00000528880.3
hydroxycarboxylic acid receptor 3
chr22_+_36863091 0.26 ENST00000650698.1
neutrophil cytosolic factor 4
chr3_-_120742506 0.25 ENST00000273375.8
ENST00000483733.1
RAB, member of RAS oncogene family like 3
chr17_+_42980547 0.25 ENST00000361677.5
ENST00000589705.1
RUN domain containing 1
chr19_-_38878247 0.25 ENST00000591812.2
Ras and Rab interactor like
chr2_-_2326210 0.25 ENST00000647755.1
myelin transcription factor 1 like
chr15_-_78077657 0.24 ENST00000300584.8
ENST00000409931.7
TBC1 domain family member 2B
chr6_+_31586269 0.24 ENST00000438075.7
leukocyte specific transcript 1
chr1_+_202348687 0.24 ENST00000608999.6
ENST00000391959.5
ENST00000480184.5
protein phosphatase 1 regulatory subunit 12B
chr11_-_57410113 0.24 ENST00000529411.1
novel protein
chr1_+_112674416 0.24 ENST00000413052.6
ENST00000369645.5
Mov10 RISC complex RNA helicase
chr17_+_28335718 0.23 ENST00000226225.7
TNF alpha induced protein 1
chr1_-_26306576 0.23 ENST00000421827.2
ENST00000374215.5
ENST00000374223.5
ENST00000357089.8
ENST00000314675.11
ENST00000423664.5
ENST00000374221.7
UBX domain protein 11
chr2_+_71130586 0.23 ENST00000498451.2
ENST00000244230.7
M-phase phosphoprotein 10
chr8_-_139654330 0.23 ENST00000647605.1
potassium two pore domain channel subfamily K member 9
chr15_-_100602157 0.22 ENST00000559577.5
ENST00000561308.5
ENST00000560133.5
ENST00000560941.5
ENST00000314742.13
ENST00000559736.5
ENST00000560272.1
lines homolog 1
chr5_-_59039454 0.22 ENST00000358923.10
phosphodiesterase 4D
chr6_+_31586680 0.22 ENST00000339530.8
leukocyte specific transcript 1
chr16_-_31064952 0.22 ENST00000426488.6
zinc finger protein 668
chr3_-_122416035 0.21 ENST00000330689.6
WD repeat domain 5B
chr3_+_35679690 0.21 ENST00000413378.5
ENST00000417925.5
cAMP regulated phosphoprotein 21
chr17_+_28335571 0.21 ENST00000544907.6
TNF alpha induced protein 1
chr5_+_170353480 0.21 ENST00000377360.8
potassium voltage-gated channel interacting protein 1
chr11_-_75306688 0.21 ENST00000532525.1
arrestin beta 1
chr5_-_143434677 0.21 ENST00000504572.5
nuclear receptor subfamily 3 group C member 1
chr22_+_38705922 0.21 ENST00000216044.10
GTP binding protein 1
chr16_-_31065011 0.20 ENST00000539836.3
ENST00000535577.5
ENST00000442862.2
zinc finger protein 668
chr9_+_128685062 0.20 ENST00000409104.7
SET nuclear proto-oncogene
chr11_+_6205549 0.20 ENST00000316375.3
chromosome 11 open reading frame 42
chr4_+_80197493 0.20 ENST00000415738.3
PR/SET domain 8
chr1_-_36450410 0.20 ENST00000356637.9
ENST00000354267.3
ENST00000235532.9
organic solute carrier partner 1
chr8_+_12104389 0.20 ENST00000400085.7
zinc finger protein 705D
chr19_-_3546306 0.20 ENST00000398558.8
major facilitator superfamily domain containing 12
chr8_+_32721823 0.19 ENST00000539990.3
ENST00000519240.5
neuregulin 1
chr18_+_34593392 0.19 ENST00000684377.1
dystrobrevin alpha
chr19_+_32691783 0.19 ENST00000397061.4
nudix hydrolase 19
chr2_+_102187015 0.19 ENST00000441515.3
ENST00000264257.7
interleukin 1 receptor like 2
chr6_-_26216673 0.18 ENST00000541790.3
H2B clustered histone 8
chr21_+_32298945 0.18 ENST00000339944.4
melanocortin 2 receptor accessory protein
chr19_-_15808126 0.18 ENST00000334920.3
olfactory receptor family 10 subfamily H member 1
chr21_+_32298849 0.18 ENST00000303645.10
melanocortin 2 receptor accessory protein
chr12_-_119877270 0.18 ENST00000261833.11
ENST00000612548.4
citron rho-interacting serine/threonine kinase
chr8_+_24440930 0.17 ENST00000441335.6
ENST00000175238.10
ENST00000380789.5
ADAM metallopeptidase domain 7
chr13_-_46182136 0.17 ENST00000323076.7
lymphocyte cytosolic protein 1
chr19_+_55676621 0.17 ENST00000411543.6
epsin 1
chr5_+_151025343 0.17 ENST00000521632.1
glutathione peroxidase 3
chr10_-_110918934 0.17 ENST00000605742.5
BBSome interacting protein 1
chr18_-_77127935 0.17 ENST00000581878.5
myelin basic protein
chr3_+_38138478 0.17 ENST00000396334.8
ENST00000417037.8
ENST00000652213.1
ENST00000650112.2
ENST00000651800.2
ENST00000421516.3
ENST00000650905.2
MYD88 innate immune signal transduction adaptor
chr6_+_130827398 0.17 ENST00000541421.2
small leucine rich protein 1
chr16_+_8642375 0.17 ENST00000562973.1
methyltransferase like 22
chr22_+_38057200 0.17 ENST00000404072.7
ENST00000424694.5
protein interacting with PRKCA 1
chr22_-_43862480 0.17 ENST00000330884.9
sulfotransferase family 4A member 1
chr5_+_50665899 0.16 ENST00000505697.6
poly(ADP-ribose) polymerase family member 8
chr5_+_150190035 0.16 ENST00000230671.7
ENST00000524041.1
solute carrier family 6 member 7
chr5_+_150671588 0.16 ENST00000523553.1
myozenin 3
chr6_+_31586859 0.16 ENST00000433492.5
leukocyte specific transcript 1
chrX_-_109733181 0.16 ENST00000673016.1
acyl-CoA synthetase long chain family member 4
chrX_-_109733249 0.16 ENST00000469796.7
ENST00000672401.1
ENST00000671846.1
acyl-CoA synthetase long chain family member 4
chr11_+_10305065 0.16 ENST00000534464.1
ENST00000278175.10
ENST00000530439.1
ENST00000524948.5
ENST00000528655.5
ENST00000526492.4
ENST00000525063.2
adrenomedullin
chr4_-_36244438 0.15 ENST00000303965.9
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr2_+_172556039 0.15 ENST00000410055.5
ENST00000282077.8
pyruvate dehydrogenase kinase 1
chr9_-_133609325 0.15 ENST00000673969.1
family with sequence similarity 163 member B
chr10_-_15371225 0.15 ENST00000378116.9
family with sequence similarity 171 member A1
chr6_-_11382247 0.15 ENST00000397378.7
ENST00000513989.5
ENST00000508546.5
ENST00000504387.5
neural precursor cell expressed, developmentally down-regulated 9
chr10_+_69278492 0.15 ENST00000643399.2
hexokinase 1
chr10_-_77637789 0.15 ENST00000481070.1
ENST00000640969.1
ENST00000286628.14
ENST00000638991.1
ENST00000639913.1
ENST00000480683.2
potassium calcium-activated channel subfamily M alpha 1
chr1_-_205422050 0.15 ENST00000367153.9
LEM domain containing 1
chr8_-_73878816 0.15 ENST00000602593.6
ENST00000651945.1
ENST00000419880.7
ENST00000517608.5
ENST00000650817.1
ubiquitin conjugating enzyme E2 W
chrX_+_47561172 0.15 ENST00000377045.9
ENST00000377039.2
A-Raf proto-oncogene, serine/threonine kinase
chr11_+_31650024 0.14 ENST00000638317.1
elongator acetyltransferase complex subunit 4
chr3_-_49723903 0.14 ENST00000678010.1
ENST00000480687.5
ENST00000308388.7
ENST00000308375.10
ENST00000677393.1
ENST00000495627.2
GDP-mannose pyrophosphorylase B
chr16_-_3400963 0.14 ENST00000571906.1
ENST00000573830.1
ENST00000439568.2
ENST00000396852.9
ENST00000422427.6
ENST00000304926.7
ENST00000618425.4
ENST00000396846.8
zinc finger and SCAN domain containing 32
chr11_+_120325283 0.14 ENST00000314475.6
ENST00000375095.3
ENST00000529187.1
TLC domain containing 5
chr19_-_50476838 0.14 ENST00000600100.6
family with sequence similarity 71 member E1
chr2_-_171434763 0.14 ENST00000442778.5
ENST00000453846.5
ENST00000612742.5
methyltransferase like 8
chr1_+_46671871 0.14 ENST00000564373.1
testis expressed 38
chr10_-_75109172 0.14 ENST00000372700.7
ENST00000473072.2
ENST00000491677.6
ENST00000372702.7
dual specificity phosphatase 13
chr3_+_39051990 0.14 ENST00000302313.10
WD repeat domain 48
chr18_-_66604076 0.14 ENST00000540086.5
ENST00000580157.2
ENST00000262150.7
cadherin 19
chr17_-_31314066 0.14 ENST00000577894.1
ecotropic viral integration site 2B
chr11_+_65386611 0.14 ENST00000531296.1
ENST00000533782.5
ENST00000355991.9
ENST00000317568.10
ENST00000416776.6
ENST00000526201.1
FERM domain containing 8
chr10_-_77637721 0.13 ENST00000638848.1
ENST00000639406.1
ENST00000618048.2
ENST00000639120.1
ENST00000640834.1
ENST00000639601.1
ENST00000638514.1
ENST00000457953.6
ENST00000639090.1
ENST00000639489.1
ENST00000372440.6
ENST00000404771.8
ENST00000638203.1
ENST00000638306.1
ENST00000638351.1
ENST00000638606.1
ENST00000639591.1
ENST00000640182.1
ENST00000640605.1
ENST00000640141.1
potassium calcium-activated channel subfamily M alpha 1
chrX_-_1537165 0.13 ENST00000381297.10
P2Y receptor family member 8
chrX_+_41688967 0.13 ENST00000378142.9
G protein-coupled receptor 34
chr11_+_124865425 0.13 ENST00000397801.6
roundabout guidance receptor 3
chr6_+_31586835 0.13 ENST00000211921.11
leukocyte specific transcript 1
chrX_-_109733220 0.13 ENST00000672282.1
ENST00000340800.7
acyl-CoA synthetase long chain family member 4
chr4_+_112860981 0.13 ENST00000671704.1
ankyrin 2
chr4_-_46909206 0.13 ENST00000396533.5
cytochrome c oxidase subunit 7B2
chr1_+_46671821 0.13 ENST00000334122.5
ENST00000415500.1
testis expressed 38
chr4_+_112861053 0.13 ENST00000672221.1
ankyrin 2
chrX_-_25015924 0.12 ENST00000379044.5
aristaless related homeobox
chr7_+_144086278 0.12 ENST00000641592.1
olfactory receptor family 2 subfamily A member 12
chr14_+_39233908 0.12 ENST00000280082.4
MIA SH3 domain ER export factor 2
chr3_-_122514876 0.12 ENST00000493510.1
ENST00000476916.5
ENST00000344337.11
ENST00000465882.5
karyopherin subunit alpha 1
chr4_-_48080172 0.12 ENST00000507351.1
TXK tyrosine kinase
chr6_+_41335594 0.12 ENST00000373089.10
natural cytotoxicity triggering receptor 2
chr14_+_44897268 0.12 ENST00000325192.8
ENST00000557112.1
chromosome 14 open reading frame 28
chrX_+_41689006 0.12 ENST00000378138.5
ENST00000620846.1
ENST00000649219.1
G protein-coupled receptor 34
chr8_-_20183090 0.11 ENST00000265808.11
ENST00000522513.5
solute carrier family 18 member A1
chr9_-_25678375 0.11 ENST00000358022.6
tumor suppressor candidate 1
chr5_-_148654130 0.11 ENST00000360693.7
5-hydroxytryptamine receptor 4
chr19_-_49451793 0.11 ENST00000262265.10
PIH1 domain containing 1
chr2_-_89297785 0.11 ENST00000465170.1
immunoglobulin kappa variable 1-37 (non-functional)
chr6_+_36594354 0.11 ENST00000373715.11
serine and arginine rich splicing factor 3
chr8_-_20183127 0.11 ENST00000276373.10
ENST00000519026.5
ENST00000440926.3
ENST00000437980.3
solute carrier family 18 member A1
chrX_+_134807129 0.11 ENST00000646004.1
PABIR family member 3
chr13_-_23433676 0.11 ENST00000682547.1
ENST00000455470.6
ENST00000382292.9
sacsin molecular chaperone
chr9_+_133030675 0.11 ENST00000372099.10
ENST00000440319.5
general transcription factor IIIC subunit 5
chr2_-_24047348 0.11 ENST00000406895.3
WD repeat and coiled coil containing
chr11_-_14499833 0.11 ENST00000249923.7
ENST00000529866.5
COPI coat complex subunit beta 1
chr6_+_133952162 0.11 ENST00000416965.5
ENST00000613034.4
TATA-box binding protein like 1
chr1_+_248030070 0.11 ENST00000642011.1
ENST00000641771.1
olfactory receptor family 2 subfamily L member 2
chr19_-_45076465 0.11 ENST00000303809.7
zinc finger protein 296
chr2_-_95121788 0.11 ENST00000272418.7
mitochondrial ribosomal protein S5
chr17_-_28335421 0.11 ENST00000578122.5
ENST00000579419.5
ENST00000585313.5
ENST00000578985.5
ENST00000577498.1
ENST00000585089.5
ENST00000357896.7
ENST00000395418.8
ENST00000588477.5
intraflagellar transport 20
chr15_-_33194696 0.11 ENST00000320930.7
ENST00000616417.5
formin 1
chr16_+_32252719 0.10 ENST00000398664.4
TP53 target 3D
chr4_-_99290975 0.10 ENST00000209668.3
alcohol dehydrogenase 1A (class I), alpha polypeptide
chr2_-_24047375 0.10 ENST00000295148.9
WD repeat and coiled coil containing
chr16_-_71724700 0.10 ENST00000568954.5
PH domain and leucine rich repeat protein phosphatase 2
chr8_+_144477975 0.10 ENST00000435887.2
protein phosphatase 1 regulatory subunit 16A
chr14_-_102362714 0.10 ENST00000536961.6
ENST00000541568.6
ENST00000216756.11
cyclin dependent kinase 2 interacting protein
chr4_-_46909235 0.10 ENST00000505102.1
ENST00000355591.8
cytochrome c oxidase subunit 7B2
chr3_+_25790076 0.10 ENST00000280701.8
ENST00000420173.2
3-oxoacyl-ACP synthase, mitochondrial
chr3_+_102099244 0.10 ENST00000491959.5
zona pellucida like domain containing 1
chr13_-_23433735 0.10 ENST00000423156.2
ENST00000683210.1
ENST00000682775.1
ENST00000684497.1
ENST00000682944.1
ENST00000683489.1
ENST00000684385.1
ENST00000683680.1
sacsin molecular chaperone
chr4_+_112818088 0.10 ENST00000673044.1
ENST00000672696.1
ENST00000672315.1
ENST00000672088.1
ENST00000671793.1
ENST00000672402.1
ENST00000671825.1
ENST00000672312.1
ENST00000672830.1
ENST00000672731.1
ENST00000671854.1
ENST00000672350.1
ENST00000672684.1
ENST00000672934.1
ENST00000673546.1
ENST00000673573.1
ENST00000503423.6
ENST00000673255.1
ENST00000671893.1
ENST00000672246.1
ENST00000672930.1
ENST00000673334.1
ENST00000673453.1
ENST00000673555.1
ENST00000672880.1
ENST00000672990.1
ENST00000673430.1
ENST00000673298.1
ENST00000672068.1
ENST00000672362.1
ENST00000672793.1
ENST00000672209.1
ENST00000671756.1
ENST00000671809.1
ENST00000671906.1
ENST00000672090.1
ENST00000672177.1
ENST00000672759.1
ENST00000672965.1
ENST00000673109.1
ENST00000503271.5
ENST00000506722.5
ENST00000673536.1
ENST00000672986.1
ankyrin 2
chr7_+_134745460 0.10 ENST00000436461.6
caldesmon 1
chr3_+_114056728 0.10 ENST00000485050.5
ENST00000281273.8
ENST00000479882.5
ENST00000493014.1
queuine tRNA-ribosyltransferase accessory subunit 2
chr1_-_216723437 0.10 ENST00000459955.5
ENST00000366937.5
ENST00000391890.7
estrogen related receptor gamma
chr14_+_22168387 0.10 ENST00000557168.1
T cell receptor alpha variable 30
chr4_+_112818032 0.10 ENST00000672356.1
ENST00000672955.1
ankyrin 2
chr2_+_161136901 0.09 ENST00000259075.6
ENST00000432002.5
TRAF family member associated NFKB activator
chr1_-_216723410 0.09 ENST00000469486.5
ENST00000481543.1
ENST00000408911.8
estrogen related receptor gamma
chr1_-_28232996 0.09 ENST00000263697.6
DnaJ heat shock protein family (Hsp40) member C8
chr11_+_71833200 0.09 ENST00000328698.2
defensin beta 108B
chr10_+_103245887 0.09 ENST00000441178.2
ribulose-5-phosphate-3-epimerase like 1
chr8_-_48921419 0.09 ENST00000020945.4
snail family transcriptional repressor 2
chr3_-_167474026 0.09 ENST00000466903.1
ENST00000264677.8
serpin family I member 2
chr20_-_45101112 0.09 ENST00000306117.5
ENST00000537075.3
potassium voltage-gated channel modifier subfamily S member 1
chr19_+_39125769 0.09 ENST00000602004.1
ENST00000599470.5
ENST00000321944.8
ENST00000593480.5
ENST00000358301.7
ENST00000593690.5
ENST00000599386.5
p21 (RAC1) activated kinase 4
chr10_-_75109085 0.09 ENST00000607131.5
dual specificity phosphatase 13
chr5_-_115841548 0.09 ENST00000509910.2
ENST00000500945.2
autophagy related 12
chr14_+_55027576 0.09 ENST00000339298.2
suppressor of cytokine signaling 4
chr3_+_23810436 0.09 ENST00000467766.5
ENST00000424381.5
ubiquitin conjugating enzyme E2 E1
chr1_+_202348727 0.09 ENST00000356764.6
protein phosphatase 1 regulatory subunit 12B
chr3_-_111595339 0.09 ENST00000317012.5
zinc finger BED-type containing 2
chr10_-_103153609 0.09 ENST00000675985.1
5'-nucleotidase, cytosolic II
chr10_+_17752185 0.09 ENST00000377495.2
transmembrane protein 236
chr6_-_70283105 0.08 ENST00000683980.1
collagen type IX alpha 1 chain
chr3_+_156674579 0.08 ENST00000295924.12
TCDD inducible poly(ADP-ribose) polymerase
chr1_+_224952670 0.08 ENST00000366848.5
ENST00000439375.6
dynein axonemal heavy chain 14
chr17_-_31314040 0.08 ENST00000330927.5
ecotropic viral integration site 2B
chr17_-_8152380 0.08 ENST00000317276.9
period circadian regulator 1
chr2_+_63842325 0.08 ENST00000445915.6
ENST00000475462.5
UDP-glucose pyrophosphorylase 2
chr19_-_45076504 0.08 ENST00000622376.1
zinc finger protein 296
chr6_-_43059367 0.08 ENST00000230413.9
ENST00000487429.1
ENST00000388752.8
ENST00000489623.1
ENST00000468957.1
mitochondrial ribosomal protein L2
chr12_-_47725558 0.08 ENST00000229003.7
endonuclease, poly(U) specific
chr19_-_1401487 0.08 ENST00000640762.1
ENST00000252288.8
ENST00000447102.8
guanidinoacetate N-methyltransferase

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0034344 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.2 2.0 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.1 0.6 GO:0003350 pulmonary myocardium development(GO:0003350)
0.1 1.3 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.1 0.3 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.1 0.9 GO:0071492 cellular response to UV-A(GO:0071492)
0.1 0.3 GO:0099558 maintenance of synapse structure(GO:0099558)
0.1 0.4 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.1 0.7 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.1 0.3 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.1 0.5 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.1 0.4 GO:1902731 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) negative regulation of chondrocyte proliferation(GO:1902731)
0.1 0.3 GO:1903826 arginine transmembrane transport(GO:1903826)
0.0 0.4 GO:0036371 protein localization to T-tubule(GO:0036371)
0.0 0.4 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 0.4 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.0 0.2 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.0 0.1 GO:1903939 negative regulation of histone H3-K9 dimethylation(GO:1900110) regulation of TORC2 signaling(GO:1903939)
0.0 0.0 GO:0060434 bronchus morphogenesis(GO:0060434)
0.0 0.1 GO:0070898 RNA polymerase III transcriptional preinitiation complex assembly(GO:0070898)
0.0 0.1 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.0 0.8 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.4 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.2 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.0 0.2 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.0 0.3 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.0 0.3 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.0 0.2 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.0 0.1 GO:1901420 negative regulation of response to alcohol(GO:1901420)
0.0 0.2 GO:1904209 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.0 0.4 GO:0042354 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 1.4 GO:0032461 positive regulation of protein oligomerization(GO:0032461)
0.0 0.2 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065) glucose 1-phosphate metabolic process(GO:0019255)
0.0 0.2 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.0 0.2 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.4 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.1 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.0 0.2 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.0 0.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.2 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.3 GO:0034465 response to carbon monoxide(GO:0034465)
0.0 0.1 GO:0009212 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
0.0 0.2 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.0 0.1 GO:0072092 ureteric bud invasion(GO:0072092)
0.0 0.1 GO:0060369 positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
0.0 0.1 GO:0051792 short-chain fatty acid biosynthetic process(GO:0051790) medium-chain fatty acid biosynthetic process(GO:0051792)
0.0 0.1 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.0 0.1 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0 0.2 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.0 0.1 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.0 0.1 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.1 GO:0035385 Roundabout signaling pathway(GO:0035385)
0.0 0.1 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.0 0.0 GO:0072312 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715) metanephric glomerular epithelium development(GO:0072244) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313) regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
0.0 0.1 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.1 GO:0021831 embryonic olfactory bulb interneuron precursor migration(GO:0021831)
0.0 0.0 GO:0036245 cellular response to menadione(GO:0036245)
0.0 0.1 GO:0019323 pentose catabolic process(GO:0019323)
0.0 0.0 GO:0033168 conversion of ds siRNA to ss siRNA involved in RNA interference(GO:0033168) conversion of ds siRNA to ss siRNA(GO:0036404)
0.0 0.2 GO:0072656 maintenance of protein location in mitochondrion(GO:0072656)
0.0 0.4 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.0 0.2 GO:0021840 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.0 0.1 GO:1902525 regulation of protein monoubiquitination(GO:1902525)
0.0 0.1 GO:0039513 modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
0.0 0.6 GO:0048665 neuron fate specification(GO:0048665)
0.0 0.3 GO:0034656 nucleobase-containing small molecule catabolic process(GO:0034656)
0.0 0.4 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.4 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.0 0.2 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.0 GO:0090283 regulation of protein glycosylation in Golgi(GO:0090283)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.0 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.1 0.4 GO:1990037 Lewy body core(GO:1990037)
0.1 0.2 GO:0034457 Mpp10 complex(GO:0034457)
0.0 0.2 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.1 GO:1902636 kinociliary basal body(GO:1902636)
0.0 0.3 GO:0032010 phagolysosome(GO:0032010)
0.0 0.4 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.2 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 0.2 GO:0070083 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0 0.3 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.3 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 0.2 GO:0070852 cell body fiber(GO:0070852)
0.0 0.1 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 0.0 GO:0033167 ARC complex(GO:0033167)
0.0 0.1 GO:0002177 manchette(GO:0002177)
0.0 0.1 GO:0000811 GINS complex(GO:0000811)
0.0 0.1 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.0 0.1 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.3 GO:0016342 catenin complex(GO:0016342)
0.0 0.1 GO:0070761 pre-snoRNP complex(GO:0070761)
0.0 0.2 GO:0034464 BBSome(GO:0034464)
0.0 0.1 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.1 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.2 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 0.2 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.0 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.1 0.4 GO:0031780 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
0.1 0.4 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.1 0.4 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 0.2 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.1 0.2 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.1 2.1 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.2 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.0 0.2 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.3 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.0 0.2 GO:0051748 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.0 0.6 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0001034 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003) RNA polymerase III transcription factor activity, sequence-specific DNA binding(GO:0001034)
0.0 0.4 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 0.8 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.5 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.1 GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315)
0.0 0.4 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.1 GO:0004750 ribulose-phosphate 3-epimerase activity(GO:0004750)
0.0 0.1 GO:0050146 nucleoside phosphotransferase activity(GO:0050146)
0.0 0.3 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 0.1 GO:0002046 opsin binding(GO:0002046)
0.0 0.2 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.1 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 0.1 GO:0070568 guanylyltransferase activity(GO:0070568)
0.0 0.2 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.2 GO:0051373 FATZ binding(GO:0051373)
0.0 0.4 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.3 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.2 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.4 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.1 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.1 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.0 0.2 GO:0004396 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.2 GO:0008430 selenium binding(GO:0008430)
0.0 0.1 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.1 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0 0.1 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 2.4 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.1 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.1 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.0 0.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 0.3 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.0 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.0 0.1 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.1 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.2 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.6 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 1.4 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 1.0 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.0 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.5 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.5 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.2 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.4 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.3 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.2 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.3 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters