Project

Inflammatory response time course, HUVEC (Wada, 2009)

Navigation
Downloads

Results for NKX2-4

Z-value: 0.74

Motif logo

logo of

Transcription factors associated with NKX2-4

Gene Symbol Gene ID Gene Info
NKX2-4
ENSG00000125816.5 NKX2-4

Activity profile of NKX2-4 motif

Sorted Z-values of NKX2-4 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of NKX2-4

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:

Promoter Score Transcript Gene Gene Info
chr11_-_102780620 2.01 ENST00000279441.9
ENST00000539681.1
MMP10
matrix metallopeptidase 10
chr3_-_108058361 1.57 ENST00000398258.7
CD47
CD47 molecule
chr4_-_119628791 1.32 ENST00000354960.8
PDE5A
phosphodiesterase 5A
chr15_+_67138001 1.27 ENST00000439724.7
SMAD3
SMAD family member 3
chr19_+_45001430 1.23 ENST00000625761.2
ENST00000505236.1
ENST00000221452.13
RELB
RELB proto-oncogene, NF-kB subunit
chr1_-_89126066 1.17 ENST00000370466.4
GBP2
guanylate binding protein 2
chr7_+_134866831 1.13 ENST00000435928.1
CALD1
caldesmon 1
chr6_-_11779606 1.13 ENST00000506810.1
ADTRP
androgen dependent TFPI regulating protein
chr1_-_85404494 1.12 ENST00000633113.1
DDAH1
dimethylarginine dimethylaminohydrolase 1
chrX_-_155334580 1.11 ENST00000369449.7
ENST00000321926.4
CLIC2
chloride intracellular channel 2
chr7_+_134843884 1.08 ENST00000445569.6
CALD1
caldesmon 1
chr12_-_70788914 1.05 ENST00000342084.8
PTPRR
protein tyrosine phosphatase receptor type R
chr7_+_130293134 0.97 ENST00000445470.6
ENST00000492072.5
ENST00000222482.10
ENST00000473956.5
ENST00000493259.5
ENST00000486598.1
CPA4
carboxypeptidase A4
chr15_+_44427793 0.92 ENST00000558966.5
ENST00000559793.5
ENST00000558968.1
CTDSPL2
CTD small phosphatase like 2
chr1_-_120051714 0.89 ENST00000579475.7
NOTCH2
notch receptor 2
chr7_-_115968302 0.86 ENST00000457268.5
TFEC
transcription factor EC
chr12_+_10505602 0.85 ENST00000322446.3
EIF2S3B
eukaryotic translation initiation factor 2 subunit gamma B
chr16_+_1680337 0.81 ENST00000566691.5
ENST00000382710.8
JPT2
Jupiter microtubule associated homolog 2
chr21_+_36135071 0.79 ENST00000290354.6
CBR3
carbonyl reductase 3
chr2_+_161136901 0.79 ENST00000259075.6
ENST00000432002.5
TANK
TRAF family member associated NFKB activator
chr18_-_36122110 0.77 ENST00000586829.1
SLC39A6
solute carrier family 39 member 6
chr19_+_10655023 0.76 ENST00000590009.5
ILF3
interleukin enhancer binding factor 3
chr20_-_18413216 0.76 ENST00000480488.2
DZANK1
double zinc ribbon and ankyrin repeat domains 1
chr2_-_37672178 0.75 ENST00000457889.1
CDC42EP3
CDC42 effector protein 3
chr4_+_95091462 0.74 ENST00000264568.8
BMPR1B
bone morphogenetic protein receptor type 1B
chr6_+_45422564 0.74 ENST00000625924.1
RUNX2
RUNX family transcription factor 2
chr15_-_58014097 0.74 ENST00000559517.5
ALDH1A2
aldehyde dehydrogenase 1 family member A2
chr7_+_151341764 0.73 ENST00000413040.7
ENST00000470229.6
ENST00000568733.6
NUB1
negative regulator of ubiquitin like proteins 1
chr11_-_60952559 0.72 ENST00000538739.2
SLC15A3
solute carrier family 15 member 3
chr5_+_68288346 0.71 ENST00000320694.12
PIK3R1
phosphoinositide-3-kinase regulatory subunit 1
chr6_+_82363199 0.69 ENST00000535040.4
TPBG
trophoblast glycoprotein
chr2_-_37672448 0.67 ENST00000611976.1
CDC42EP3
CDC42 effector protein 3
chr11_-_106022209 0.67 ENST00000301919.9
ENST00000534458.1
ENST00000530108.1
ENST00000530788.1
MSANTD4
Myb/SANT DNA binding domain containing 4 with coiled-coils
chrX_+_135309480 0.67 ENST00000635820.1
ETDC
embryonic testis differentiation homolog C
chr6_+_45422485 0.65 ENST00000359524.7
RUNX2
RUNX family transcription factor 2
chr11_+_35943981 0.64 ENST00000528989.5
ENST00000524419.5
ENST00000315571.6
LDLRAD3
low density lipoprotein receptor class A domain containing 3
chr5_-_59216826 0.63 ENST00000638939.1
PDE4D
phosphodiesterase 4D
chr10_+_97572771 0.62 ENST00000370655.6
ENST00000455090.1
ANKRD2
ankyrin repeat domain 2
chr14_+_51489112 0.58 ENST00000356218.8
FRMD6
FERM domain containing 6
chr7_-_29195186 0.58 ENST00000449801.5
ENST00000409850.5
CPVL
carboxypeptidase vitellogenic like
chr15_-_55249029 0.56 ENST00000566877.5
RAB27A
RAB27A, member RAS oncogene family
chr11_-_19202004 0.56 ENST00000648719.1
CSRP3
cysteine and glycine rich protein 3
chr8_+_31639291 0.56 ENST00000651149.1
ENST00000650866.1
NRG1
neuregulin 1
chrX_+_30243715 0.56 ENST00000378981.8
ENST00000397550.6
MAGEB1
MAGE family member B1
chr5_+_173918186 0.55 ENST00000657000.1
CPEB4
cytoplasmic polyadenylation element binding protein 4
chr2_-_174597728 0.54 ENST00000409891.5
ENST00000410117.5
WIPF1
WAS/WASL interacting protein family member 1
chr5_+_177087412 0.53 ENST00000513166.1
FGFR4
fibroblast growth factor receptor 4
chr4_-_102825767 0.53 ENST00000505207.5
ENST00000502404.5
ENST00000507845.5
UBE2D3
ubiquitin conjugating enzyme E2 D3
chr6_+_125919210 0.52 ENST00000438495.6
NCOA7
nuclear receptor coactivator 7
chr8_+_31639222 0.52 ENST00000519301.6
ENST00000652698.1
NRG1
neuregulin 1
chr5_+_173918216 0.51 ENST00000519467.1
CPEB4
cytoplasmic polyadenylation element binding protein 4
chr6_+_125919296 0.51 ENST00000444128.2
NCOA7
nuclear receptor coactivator 7
chr13_-_108215498 0.50 ENST00000614526.1
ENST00000611712.4
ENST00000442234.6
LIG4
DNA ligase 4
chr4_+_85827745 0.50 ENST00000509300.5
ARHGAP24
Rho GTPase activating protein 24
chr4_+_85827891 0.50 ENST00000514229.5
ARHGAP24
Rho GTPase activating protein 24
chr21_-_14546297 0.50 ENST00000400566.6
ENST00000400564.5
SAMSN1
SAM domain, SH3 domain and nuclear localization signals 1
chr11_-_86069811 0.50 ENST00000531930.5
ENST00000528398.5
PICALM
phosphatidylinositol binding clathrin assembly protein
chr16_+_83998252 0.50 ENST00000564166.1
NECAB2
N-terminal EF-hand calcium binding protein 2
chr21_-_14546351 0.50 ENST00000619120.4
SAMSN1
SAM domain, SH3 domain and nuclear localization signals 1
chr4_-_102825526 0.50 ENST00000504211.5
ENST00000508476.5
UBE2D3
ubiquitin conjugating enzyme E2 D3
chr4_-_102825854 0.49 ENST00000350435.11
UBE2D3
ubiquitin conjugating enzyme E2 D3
chr11_+_61950343 0.49 ENST00000378043.9
BEST1
bestrophin 1
chr12_+_112978562 0.47 ENST00000680122.1
OAS2
2'-5'-oligoadenylate synthetase 2
chr2_+_161160420 0.47 ENST00000392749.7
ENST00000405852.5
TANK
TRAF family member associated NFKB activator
chr4_-_121381007 0.47 ENST00000394427.3
QRFPR
pyroglutamylated RFamide peptide receptor
chr1_-_94925759 0.47 ENST00000415017.1
ENST00000545882.5
CNN3
calponin 3
chr5_+_138084015 0.46 ENST00000504809.5
ENST00000506684.6
ENST00000398754.1
WNT8A
Wnt family member 8A
chr18_-_27990256 0.46 ENST00000675173.1
CDH2
cadherin 2
chr17_-_42112674 0.46 ENST00000251642.8
ENST00000591220.5
DHX58
DExH-box helicase 58
chr6_-_36024635 0.45 ENST00000490799.6
SLC26A8
solute carrier family 26 member 8
chr11_+_60931744 0.45 ENST00000536409.1
TMEM132A
transmembrane protein 132A
chr11_-_86068929 0.45 ENST00000630913.2
PICALM
phosphatidylinositol binding clathrin assembly protein
chr6_-_36024493 0.44 ENST00000394602.6
ENST00000355574.6
SLC26A8
solute carrier family 26 member 8
chr10_+_58334998 0.44 ENST00000373910.9
UBE2D1
ubiquitin conjugating enzyme E2 D1
chr6_+_37257762 0.44 ENST00000373491.3
TBC1D22B
TBC1 domain family member 22B
chr1_+_202462730 0.43 ENST00000290419.9
ENST00000491336.5
PPP1R12B
protein phosphatase 1 regulatory subunit 12B
chr20_-_21514046 0.43 ENST00000377142.5
NKX2-2
NK2 homeobox 2
chr10_+_58334976 0.42 ENST00000615793.1
UBE2D1
ubiquitin conjugating enzyme E2 D1
chr4_-_173399102 0.41 ENST00000296506.8
SCRG1
stimulator of chondrogenesis 1
chr2_-_100142575 0.41 ENST00000317233.8
ENST00000672204.1
ENST00000416492.5
ENST00000672857.1
ENST00000672756.2
AFF3
AF4/FMR2 family member 3
chr18_+_58149314 0.40 ENST00000435432.6
ENST00000357895.9
ENST00000586263.5
NEDD4L
NEDD4 like E3 ubiquitin protein ligase
chr5_-_160852200 0.38 ENST00000327245.10
ATP10B
ATPase phospholipid transporting 10B (putative)
chr11_+_61950370 0.38 ENST00000449131.6
BEST1
bestrophin 1
chr11_-_86069043 0.37 ENST00000532317.5
ENST00000528256.1
ENST00000393346.8
ENST00000526033.5
PICALM
phosphatidylinositol binding clathrin assembly protein
chr1_+_4654601 0.36 ENST00000378191.5
AJAP1
adherens junctions associated protein 1
chr4_-_21544650 0.35 ENST00000509207.1
KCNIP4
potassium voltage-gated channel interacting protein 4
chr20_-_23605917 0.35 ENST00000376971.4
CST9
cystatin 9
chr11_-_11353241 0.33 ENST00000528848.3
CSNK2A3
casein kinase 2 alpha 3
chr6_-_136289778 0.33 ENST00000530767.5
ENST00000527759.5
BCLAF1
BCL2 associated transcription factor 1
chr10_+_68956158 0.32 ENST00000354185.9
DDX21
DExD-box helicase 21
chr1_-_205449924 0.32 ENST00000367154.5
LEMD1
LEM domain containing 1
chr11_-_16356538 0.32 ENST00000683767.1
SOX6
SRY-box transcription factor 6
chr12_-_213338 0.31 ENST00000424061.6
SLC6A12
solute carrier family 6 member 12
chr12_-_21775045 0.31 ENST00000667884.1
KCNJ8
potassium inwardly rectifying channel subfamily J member 8
chr7_+_143477873 0.31 ENST00000408916.1
TAS2R41
taste 2 receptor member 41
chr4_+_70197924 0.31 ENST00000514097.5
ODAM
odontogenic, ameloblast associated
chr3_-_156555083 0.31 ENST00000265044.7
ENST00000476217.5
SSR3
signal sequence receptor subunit 3
chr1_-_217076889 0.30 ENST00000493748.5
ENST00000463665.5
ESRRG
estrogen related receptor gamma
chr3_+_173584433 0.30 ENST00000361589.8
NLGN1
neuroligin 1
chr5_+_148063971 0.30 ENST00000398454.5
ENST00000359874.7
ENST00000508733.5
ENST00000256084.8
SPINK5
serine peptidase inhibitor Kazal type 5
chr10_-_67696115 0.29 ENST00000433211.7
CTNNA3
catenin alpha 3
chr5_-_132543513 0.29 ENST00000231454.6
IL5
interleukin 5
chr4_-_144140635 0.29 ENST00000512064.5
ENST00000512789.5
ENST00000504786.5
ENST00000503627.2
ENST00000642713.1
ENST00000643148.1
ENST00000642738.1
ENST00000642295.1
ENST00000646447.1
ENST00000535709.6
GYPA
glycophorin A (MNS blood group)
chr11_-_19201976 0.29 ENST00000647990.1
ENST00000649235.1
ENST00000265968.9
ENST00000649842.1
CSRP3
cysteine and glycine rich protein 3
chr17_+_44846318 0.29 ENST00000591513.5
HIGD1B
HIG1 hypoxia inducible domain family member 1B
chr1_+_207645114 0.29 ENST00000508064.7
CR1L
complement C3b/C4b receptor 1 like
chr7_+_20647388 0.29 ENST00000258738.10
ABCB5
ATP binding cassette subfamily B member 5
chr1_+_147902789 0.27 ENST00000369235.2
GJA8
gap junction protein alpha 8
chr1_-_100178215 0.27 ENST00000370138.1
ENST00000370137.6
ENST00000342895.7
ENST00000620882.4
LRRC39
leucine rich repeat containing 39
chr10_+_71396905 0.26 ENST00000224721.12
ENST00000398809.9
ENST00000461841.7
ENST00000299366.11
ENST00000644511.1
ENST00000616684.4
CDH23
cadherin related 23
chr13_-_108218293 0.26 ENST00000405925.2
LIG4
DNA ligase 4
chr1_+_15659869 0.26 ENST00000345034.1
RSC1A1
regulator of solute carriers 1
chr16_-_31150058 0.26 ENST00000569305.1
ENST00000268281.9
ENST00000418068.6
PRSS36
serine protease 36
chr12_-_84892120 0.26 ENST00000680379.1
SLC6A15
solute carrier family 6 member 15
chr15_+_41286011 0.26 ENST00000661438.1
ENSG00000285920.2
novel protein
chr18_+_11851404 0.25 ENST00000526991.3
CHMP1B
charged multivesicular body protein 1B
chrX_+_78945332 0.25 ENST00000544091.1
ENST00000171757.3
P2RY10
P2Y receptor family member 10
chr14_-_81427390 0.24 ENST00000555447.5
STON2
stonin 2
chr12_+_49295138 0.24 ENST00000257860.9
PRPH
peripherin
chr16_+_10743786 0.24 ENST00000574334.5
ENST00000283027.10
ENST00000433392.6
NUBP1
nucleotide binding protein 1
chr5_-_11588842 0.23 ENST00000503622.5
CTNND2
catenin delta 2
chr19_+_10718114 0.23 ENST00000408974.8
DNM2
dynamin 2
chr12_-_14938508 0.23 ENST00000266397.7
ERP27
endoplasmic reticulum protein 27
chr1_-_241357085 0.23 ENST00000366564.5
RGS7
regulator of G protein signaling 7
chr1_-_88992616 0.23 ENST00000260508.9
ENST00000652648.1
KYAT3
RBMXL1
kynurenine aminotransferase 3
RBMX like 1
chr10_+_103245887 0.23 ENST00000441178.2
RPEL1
ribulose-5-phosphate-3-epimerase like 1
chr12_+_1970809 0.23 ENST00000683781.1
ENST00000682462.1
CACNA1C
calcium voltage-gated channel subunit alpha1 C
chr19_+_48756067 0.23 ENST00000222157.5
FGF21
fibroblast growth factor 21
chr4_-_99352730 0.23 ENST00000510055.5
ENST00000515683.6
ENST00000511397.3
ADH1C
alcohol dehydrogenase 1C (class I), gamma polypeptide
chr6_-_152637351 0.23 ENST00000367255.10
SYNE1
spectrin repeat containing nuclear envelope protein 1
chrX_+_71223216 0.23 ENST00000361726.7
GJB1
gap junction protein beta 1
chr22_-_50085331 0.23 ENST00000395876.6
MLC1
modulator of VRAC current 1
chr1_-_241357225 0.22 ENST00000366565.5
RGS7
regulator of G protein signaling 7
chr9_+_37667997 0.22 ENST00000539465.5
FRMPD1
FERM and PDZ domain containing 1
chr1_+_109090726 0.22 ENST00000338272.9
ENST00000651489.1
TMEM167B
transmembrane protein 167B
chr12_+_1970772 0.22 ENST00000682544.1
CACNA1C
calcium voltage-gated channel subunit alpha1 C
chr22_-_50085414 0.22 ENST00000311597.10
MLC1
modulator of VRAC current 1
chr19_+_37507129 0.22 ENST00000586138.5
ENST00000588578.5
ENST00000587986.5
ZNF793
zinc finger protein 793
chr12_+_8822610 0.21 ENST00000299698.12
A2ML1
alpha-2-macroglobulin like 1
chr1_-_241357171 0.21 ENST00000440928.6
RGS7
regulator of G protein signaling 7
chr7_-_107803215 0.21 ENST00000340010.10
ENST00000453332.1
SLC26A3
solute carrier family 26 member 3
chr1_-_116667668 0.21 ENST00000369486.8
ENST00000369483.5
IGSF3
immunoglobulin superfamily member 3
chr21_-_33491386 0.20 ENST00000617313.4
ENST00000314399.3
DNAJC28
DnaJ heat shock protein family (Hsp40) member C28
chr5_-_135452318 0.20 ENST00000537858.2
TIFAB
TIFA inhibitor
chr17_+_28357638 0.20 ENST00000292114.8
ENST00000591482.1
TMEM199
ENSG00000258924.4
transmembrane protein 199
novel transcript readthrough between TMEM199 and SARM1
chrX_-_15854743 0.20 ENST00000450644.2
AP1S2
adaptor related protein complex 1 subunit sigma 2
chr18_+_63542365 0.20 ENST00000269491.6
ENST00000382768.2
SERPINB12
serpin family B member 12
chr10_-_119536533 0.20 ENST00000392865.5
RGS10
regulator of G protein signaling 10
chr19_+_21082190 0.20 ENST00000618422.1
ENST00000618008.4
ENST00000425625.5
ENST00000456283.7
ZNF714
zinc finger protein 714
chr19_-_9936501 0.19 ENST00000264833.9
OLFM2
olfactomedin 2
chr19_-_17448664 0.19 ENST00000341130.6
TMEM221
transmembrane protein 221
chr11_+_78063851 0.19 ENST00000281030.2
THRSP
thyroid hormone responsive
chr22_-_36817510 0.19 ENST00000443735.1
PVALB
parvalbumin
chr1_+_156338619 0.19 ENST00000481479.5
ENST00000368252.5
ENST00000466306.5
ENST00000368251.1
TSACC
TSSK6 activating cochaperone
chrX_-_11290478 0.19 ENST00000380717.7
ARHGAP6
Rho GTPase activating protein 6
chr6_+_101398788 0.19 ENST00000369138.5
ENST00000413795.5
ENST00000358361.7
GRIK2
glutamate ionotropic receptor kainate type subunit 2
chr1_-_204213943 0.19 ENST00000308302.4
GOLT1A
golgi transport 1A
chr3_+_46370854 0.18 ENST00000292303.4
CCR5
C-C motif chemokine receptor 5
chr19_+_7669043 0.18 ENST00000221515.6
RETN
resistin
chr15_+_74174403 0.18 ENST00000560862.1
ENST00000395118.1
ISLR
immunoglobulin superfamily containing leucine rich repeat
chr6_-_30075767 0.18 ENST00000244360.8
ENST00000376751.8
RNF39
ring finger protein 39
chr2_-_208190001 0.18 ENST00000451346.5
ENST00000341287.9
C2orf80
chromosome 2 open reading frame 80
chr1_-_42335869 0.18 ENST00000372573.5
FOXJ3
forkhead box J3
chr19_+_21082224 0.18 ENST00000620627.1
ZNF714
zinc finger protein 714
chr3_-_185923893 0.18 ENST00000259043.11
TRA2B
transformer 2 beta homolog
chr14_-_70600643 0.18 ENST00000554963.5
ENST00000256379.10
ENST00000430055.6
ENST00000440435.2
ENST00000615788.4
MED6
mediator complex subunit 6
chrX_-_139832235 0.18 ENST00000327569.7
ENST00000361648.6
ATP11C
ATPase phospholipid transporting 11C
chr1_+_175067831 0.18 ENST00000239462.9
TNN
tenascin N
chr14_-_22589157 0.18 ENST00000538631.1
ENST00000543337.1
ENST00000250498.9
DAD1
defender against cell death 1
chr20_-_45101112 0.18 ENST00000306117.5
ENST00000537075.3
KCNS1
potassium voltage-gated channel modifier subfamily S member 1
chr6_+_26156323 0.18 ENST00000304218.6
H1-4
H1.4 linker histone, cluster member
chr10_+_79512533 0.18 ENST00000520547.4
EIF5AL1
eukaryotic translation initiation factor 5A like 1
chr4_-_174522791 0.17 ENST00000541923.5
ENST00000542498.5
HPGD
15-hydroxyprostaglandin dehydrogenase
chr2_-_201619144 0.17 ENST00000439802.5
ENST00000286195.7
ENST00000439140.6
ENST00000450242.1
C2CD6
C2 calcium dependent domain containing 6
chr1_+_152878312 0.17 ENST00000368765.4
SMCP
sperm mitochondria associated cysteine rich protein
chr14_+_22226711 0.17 ENST00000390463.3
TRAV36DV7
T cell receptor alpha variable 36/delta variable 7
chr11_-_33161502 0.17 ENST00000438862.6
CSTF3
cleavage stimulation factor subunit 3
chr6_-_29487956 0.17 ENST00000377127.4
MAS1L
MAS1 proto-oncogene like, G protein-coupled receptor
chr1_-_212414815 0.17 ENST00000261455.9
ENST00000535273.2
PACC1
proton activated chloride channel 1
chr20_-_44651683 0.17 ENST00000537820.1
ENST00000372874.9
ADA
adenosine deaminase
chr22_-_29061831 0.17 ENST00000216071.5
C22orf31
chromosome 22 open reading frame 31
chr4_+_168497044 0.16 ENST00000505667.6
PALLD
palladin, cytoskeletal associated protein
chr2_-_151971750 0.16 ENST00000636598.1
CACNB4
calcium voltage-gated channel auxiliary subunit beta 4
chr12_+_100503352 0.16 ENST00000551379.5
ENST00000188403.7
NR1H4
nuclear receptor subfamily 1 group H member 4
chr16_+_77788554 0.16 ENST00000302536.3
VAT1L
vesicle amine transport 1 like
chr2_+_100974849 0.16 ENST00000450763.1
NPAS2
neuronal PAS domain protein 2
chr5_+_162067764 0.16 ENST00000639213.2
ENST00000414552.6
GABRG2
gamma-aminobutyric acid type A receptor subunit gamma2
chrX_-_111412162 0.16 ENST00000637570.1
ENST00000356220.8
ENST00000636035.2
ENST00000637453.1
ENST00000635795.1
DCX
doublecortin
chr11_-_33161461 0.16 ENST00000323959.9
ENST00000431742.2
ENST00000524827.6
CSTF3
cleavage stimulation factor subunit 3
chr8_+_7848000 0.16 ENST00000326558.9
ENST00000351436.8
ENST00000528033.3
SPAG11A
sperm associated antigen 11A
chr11_-_104164361 0.16 ENST00000302251.9
PDGFD
platelet derived growth factor D
chr3_+_4493471 0.16 ENST00000544951.6
ENST00000650294.1
ITPR1
inositol 1,4,5-trisphosphate receptor type 1
chr19_-_49813259 0.15 ENST00000313777.9
FUZ
fuzzy planar cell polarity protein
chr17_+_30477362 0.15 ENST00000225724.9
ENST00000451249.7
ENST00000467337.6
ENST00000581721.5
ENST00000414833.2
GOSR1
golgi SNAP receptor complex member 1
chr15_-_85794902 0.15 ENST00000337975.6
KLHL25
kelch like family member 25
chr2_+_190180835 0.15 ENST00000340623.4
C2orf88
chromosome 2 open reading frame 88
chr4_+_168497066 0.15 ENST00000261509.10
PALLD
palladin, cytoskeletal associated protein
chr1_+_160127672 0.15 ENST00000447527.1
ATP1A2
ATPase Na+/K+ transporting subunit alpha 2
chr16_-_67966793 0.15 ENST00000541864.6
SLC12A4
solute carrier family 12 member 4
chr5_+_162067858 0.15 ENST00000361925.9
GABRG2
gamma-aminobutyric acid type A receptor subunit gamma2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.3 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.2 1.3 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.2 1.3 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.2 1.3 GO:1902963 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.2 1.0 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.2 0.8 GO:0042376 phylloquinone metabolic process(GO:0042374) phylloquinone catabolic process(GO:0042376) quinone catabolic process(GO:1901662)
0.2 0.5 GO:0014034 neural crest cell fate commitment(GO:0014034) canonical Wnt signaling pathway involved in neural crest cell differentiation(GO:0044335)
0.2 1.4 GO:0002051 osteoblast fate commitment(GO:0002051)
0.1 0.7 GO:0021780 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.1 0.8 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.1 0.5 GO:1904021 negative regulation of G-protein coupled receptor internalization(GO:1904021)
0.1 0.8 GO:0035995 detection of muscle stretch(GO:0035995)
0.1 0.5 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.1 0.4 GO:2000314 regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.1 0.7 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) negative regulation of chondrocyte proliferation(GO:1902731)
0.1 0.6 GO:0003383 apical constriction(GO:0003383)
0.1 0.3 GO:0045643 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.1 0.3 GO:0048058 compound eye corneal lens development(GO:0048058)
0.1 0.4 GO:1904640 response to methionine(GO:1904640)
0.1 0.6 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.1 0.2 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.1 1.1 GO:0021840 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.1 0.7 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.1 0.9 GO:0030321 transepithelial chloride transport(GO:0030321)
0.1 1.1 GO:0019532 oxalate transport(GO:0019532)
0.1 1.4 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.1 0.2 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
0.1 0.5 GO:1903412 response to bile acid(GO:1903412)
0.1 0.3 GO:0098923 retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543)
0.1 0.2 GO:1900111 positive regulation of histone H3-K9 dimethylation(GO:1900111)
0.1 1.6 GO:0008228 opsonization(GO:0008228)
0.1 1.1 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.1 0.2 GO:0048213 Golgi vesicle prefusion complex stabilization(GO:0048213)
0.1 0.2 GO:0098583 mastication(GO:0071626) learned vocalization behavior(GO:0098583)
0.1 1.2 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.1 0.6 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1 1.1 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.1 0.1 GO:1903015 regulation of exo-alpha-sialidase activity(GO:1903015)
0.1 0.4 GO:0030860 regulation of polarized epithelial cell differentiation(GO:0030860)
0.1 1.1 GO:0006527 arginine catabolic process(GO:0006527)
0.1 0.2 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.1 1.0 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.1 0.9 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 0.9 GO:1902916 positive regulation of protein polyubiquitination(GO:1902916)
0.1 0.2 GO:2000439 positive regulation of monocyte extravasation(GO:2000439)
0.1 0.5 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.1 0.2 GO:1900920 regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920)
0.0 0.3 GO:1900425 negative regulation of defense response to bacterium(GO:1900425)
0.0 0.2 GO:2000196 positive regulation of female gonad development(GO:2000196)
0.0 0.8 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.5 GO:0018377 protein myristoylation(GO:0018377)
0.0 0.1 GO:1904933 regulation of cell proliferation in midbrain(GO:1904933)
0.0 0.4 GO:0035585 calcium-mediated signaling using extracellular calcium source(GO:0035585)
0.0 0.2 GO:1903314 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.0 0.1 GO:0006288 base-excision repair, DNA ligation(GO:0006288)
0.0 0.1 GO:1901420 negative regulation of response to alcohol(GO:1901420)
0.0 0.1 GO:0034970 histone H3-R2 methylation(GO:0034970)
0.0 0.3 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.0 0.3 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0 0.1 GO:1900147 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.0 0.4 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.1 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.7 GO:0051531 NFAT protein import into nucleus(GO:0051531)
0.0 0.6 GO:2000291 regulation of myoblast proliferation(GO:2000291)
0.0 0.2 GO:0007341 penetration of zona pellucida(GO:0007341)
0.0 0.1 GO:1901355 response to rapamycin(GO:1901355)
0.0 0.2 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.0 0.1 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.0 0.2 GO:0097052 L-kynurenine metabolic process(GO:0097052)
0.0 0.2 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052) pentose catabolic process(GO:0019323)
0.0 0.9 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.4 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.0 0.1 GO:0003095 pressure natriuresis(GO:0003095)
0.0 0.7 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.3 GO:0050957 equilibrioception(GO:0050957)
0.0 1.5 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.1 GO:0035625 negative regulation of epinephrine secretion(GO:0032811) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625)
0.0 0.1 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 0.3 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.3 GO:0035524 proline transmembrane transport(GO:0035524)
0.0 0.1 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.0 0.2 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 0.2 GO:0045905 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 0.1 GO:0070858 negative regulation of bile acid biosynthetic process(GO:0070858) negative regulation of bile acid metabolic process(GO:1904252)
0.0 0.2 GO:0043578 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.2 GO:0044800 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.0 0.1 GO:0090579 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.0 0.1 GO:0030961 peptidyl-arginine hydroxylation(GO:0030961)
0.0 0.3 GO:1904903 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.0 0.1 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.4 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.1 GO:0043589 skin morphogenesis(GO:0043589)
0.0 0.8 GO:0050869 negative regulation of B cell activation(GO:0050869)
0.0 0.2 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.1 GO:1902748 melanocyte migration(GO:0097324) positive regulation of lens fiber cell differentiation(GO:1902748)
0.0 0.3 GO:0006069 ethanol oxidation(GO:0006069)
0.0 0.1 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.1 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.0 0.0 GO:1900133 regulation of renin secretion into blood stream(GO:1900133)
0.0 0.4 GO:0072697 protein localization to cell cortex(GO:0072697)
0.0 0.2 GO:1905146 lysosomal lumen acidification(GO:0007042) lysosomal protein catabolic process(GO:1905146)
0.0 0.1 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.0 1.5 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.2 GO:0032808 lacrimal gland development(GO:0032808)
0.0 0.3 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.2 GO:0075713 establishment of integrated proviral latency(GO:0075713)
0.0 0.3 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.0 0.2 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.4 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.2 GO:0097070 ductus arteriosus closure(GO:0097070) lipoxin metabolic process(GO:2001300)
0.0 0.1 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0 0.1 GO:0060715 syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715)
0.0 0.2 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.1 GO:0033088 regulation of immature T cell proliferation in thymus(GO:0033084) negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.0 0.0 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.2 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.0 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 0.2 GO:0016264 gap junction assembly(GO:0016264)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.2 0.7 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.1 2.2 GO:0030478 actin cap(GO:0030478)
0.1 1.3 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 0.7 GO:0032807 DNA ligase IV complex(GO:0032807)
0.1 1.2 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 0.4 GO:0044214 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.1 0.2 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.1 0.7 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.3 GO:0097209 epidermal lamellar body(GO:0097209)
0.0 0.1 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.6 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.3 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 1.1 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.8 GO:0005916 fascia adherens(GO:0005916)
0.0 0.2 GO:0070847 core mediator complex(GO:0070847)
0.0 2.7 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.1 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.0 0.4 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.5 GO:0005922 connexon complex(GO:0005922)
0.0 0.9 GO:0000791 euchromatin(GO:0000791)
0.0 0.4 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.2 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.1 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.1 GO:0033269 internode region of axon(GO:0033269)
0.0 0.3 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.1 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.2 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.7 GO:0030673 axolemma(GO:0030673)
0.0 0.8 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.2 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.2 GO:0001741 XY body(GO:0001741)
0.0 0.2 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
0.0 1.5 GO:0070821 tertiary granule membrane(GO:0070821)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.3 0.8 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.2 1.3 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.2 1.3 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.2 0.6 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.2 0.5 GO:0031687 A2A adenosine receptor binding(GO:0031687)
0.1 1.1 GO:0016403 dimethylargininase activity(GO:0016403)
0.1 1.6 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.1 1.0 GO:0038049 transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049)
0.1 0.7 GO:0015333 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.1 0.3 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.1 0.8 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.1 1.3 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 1.9 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.1 1.1 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 0.1 GO:0003909 DNA ligase activity(GO:0003909)
0.1 2.2 GO:0005523 tropomyosin binding(GO:0005523)
0.1 0.2 GO:0047315 kynurenine-glyoxylate transaminase activity(GO:0047315)
0.1 0.2 GO:0004750 ribulose-phosphate 3-epimerase activity(GO:0004750)
0.1 1.0 GO:0031433 telethonin binding(GO:0031433)
0.1 0.7 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 0.7 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.1 0.2 GO:0050567 amidase activity(GO:0004040) glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.1 0.5 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.1 0.3 GO:0017098 sulfonylurea receptor binding(GO:0017098)
0.0 0.1 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0 0.3 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.0 0.2 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.0 2.4 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.3 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.0 0.2 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.0 0.7 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.3 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.7 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.3 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 0.5 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.2 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.0 0.1 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.0 0.3 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.6 GO:0005522 profilin binding(GO:0005522)
0.0 1.1 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 1.0 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.5 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 1.1 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.7 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.9 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.3 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0 0.1 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0 0.4 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.3 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.8 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.1 GO:0004348 glucosylceramidase activity(GO:0004348)
0.0 0.1 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.5 GO:0005243 gap junction channel activity(GO:0005243)
0.0 1.4 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.6 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0000994 RNA polymerase III core binding(GO:0000994)
0.0 0.8 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.2 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.2 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.6 GO:0031489 myosin V binding(GO:0031489)
0.0 0.2 GO:1990239 steroid hormone binding(GO:1990239)
0.0 0.6 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.5 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.4 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 1.0 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.1 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.0 0.5 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.4 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.4 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.5 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.1 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 0.4 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.1 GO:0050051 alkane 1-monooxygenase activity(GO:0018685) leukotriene-B4 20-monooxygenase activity(GO:0050051)
0.0 0.2 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.3 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.1 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 1.0 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.1 GO:0042731 PH domain binding(GO:0042731)
0.0 1.8 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.0 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.1 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.0 0.4 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.3 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.2 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 1.3 GO:0003725 double-stranded RNA binding(GO:0003725)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 PID IL5 PATHWAY IL5-mediated signaling events
0.0 1.3 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 1.6 PID BARD1 PATHWAY BARD1 signaling events
0.0 1.2 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.7 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 1.6 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 1.8 PID FGF PATHWAY FGF signaling pathway
0.0 1.4 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.7 PID BMP PATHWAY BMP receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.1 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 0.9 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1 1.0 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.1 2.0 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 1.3 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.2 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 1.5 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 2.2 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 1.4 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 1.2 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.7 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.8 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 1.1 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.5 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.5 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.6 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.3 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 1.6 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.7 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.3 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.6 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 1.3 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.7 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.2 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.3 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.3 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.7 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.6 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.4 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.5 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions