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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for NKX2-5

Z-value: 0.42

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Transcription factors associated with NKX2-5

Gene Symbol Gene ID Gene Info
NKX2-5
ENSG00000183072.10 NKX2-5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NKX2-5hg38_v1_chr5_-_173235194_173235213-0.232.6e-01Click!

Activity profile of NKX2-5 motif

Sorted Z-values of NKX2-5 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of NKX2-5

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr4_+_143433491 0.76 ENST00000512843.1
GAB1
GRB2 associated binding protein 1
chr10_-_48605032 0.47 ENST00000249601.9
ARHGAP22
Rho GTPase activating protein 22
chr7_+_143222037 0.44 ENST00000408947.4
TAS2R40
taste 2 receptor member 40
chr2_+_151357583 0.41 ENST00000243347.5
TNFAIP6
TNF alpha induced protein 6
chr3_+_186996444 0.37 ENST00000676633.1
ST6GAL1
ST6 beta-galactoside alpha-2,6-sialyltransferase 1
chr3_-_15333152 0.36 ENST00000426925.5
SH3BP5
SH3 domain binding protein 5
chr5_+_141430565 0.35 ENST00000613314.1
PCDHGA12
protocadherin gamma subfamily A, 12
chr1_-_46616804 0.32 ENST00000531769.6
ENST00000319928.8
MKNK1
MOB3C
MAPK interacting serine/threonine kinase 1
MOB kinase activator 3C
chrX_-_30308333 0.26 ENST00000378963.1
NR0B1
nuclear receptor subfamily 0 group B member 1
chr7_-_122699108 0.26 ENST00000340112.3
RNF133
ring finger protein 133
chr17_+_28319149 0.26 ENST00000226230.8
ENST00000583381.5
ENST00000582113.1
ENST00000582384.1
TMEM97
transmembrane protein 97
chr7_-_44189428 0.25 ENST00000673284.1
ENST00000403799.8
ENST00000671824.1
GCK
glucokinase
chr12_+_109573757 0.24 ENST00000228510.8
ENST00000539696.5
ENST00000392727.7
MVK
mevalonate kinase
chr1_-_54887161 0.24 ENST00000535035.6
ENST00000371269.9
ENST00000436604.2
DHCR24
24-dehydrocholesterol reductase
chr17_+_59331633 0.23 ENST00000312655.9
YPEL2
yippee like 2
chr17_-_7929793 0.23 ENST00000303790.3
KCNAB3
potassium voltage-gated channel subfamily A regulatory beta subunit 3
chr12_+_93378625 0.22 ENST00000546925.1
NUDT4
nudix hydrolase 4
chr19_-_10836273 0.22 ENST00000591695.5
TMED1
transmembrane p24 trafficking protein 1
chrX_+_11759678 0.21 ENST00000649797.1
ENST00000648614.1
MSL3
MSL complex subunit 3
chr3_-_111595339 0.21 ENST00000317012.5
ZBED2
zinc finger BED-type containing 2
chr12_+_123233420 0.20 ENST00000253233.6
ENST00000366329.7
ENST00000546132.2
ENST00000536130.2
C12orf65
chromosome 12 open reading frame 65
chr3_-_11643871 0.20 ENST00000430365.7
VGLL4
vestigial like family member 4
chr1_+_202462730 0.20 ENST00000290419.9
ENST00000491336.5
PPP1R12B
protein phosphatase 1 regulatory subunit 12B
chr1_+_231162052 0.20 ENST00000366653.6
ENST00000444294.7
TRIM67
tripartite motif containing 67
chr3_-_39192584 0.19 ENST00000340369.4
ENST00000421646.1
ENST00000396251.1
XIRP1
xin actin binding repeat containing 1
chr13_+_72727749 0.19 ENST00000652266.1
ENST00000651477.1
ENST00000613797.4
BORA
BORA aurora kinase A activator
chr15_+_67067780 0.19 ENST00000679624.1
SMAD3
SMAD family member 3
chr18_-_13915531 0.18 ENST00000327606.4
MC2R
melanocortin 2 receptor
chrX_+_11759604 0.18 ENST00000649602.1
ENST00000650215.1
ENST00000649685.1
ENST00000649649.1
ENST00000380693.8
ENST00000380692.7
ENST00000650628.1
ENST00000649851.1
ENST00000421368.3
MSL3
MSL complex subunit 3
chr5_-_160685379 0.17 ENST00000642502.1
ATP10B
ATPase phospholipid transporting 10B (putative)
chr8_+_75539893 0.17 ENST00000674002.1
HNF4G
hepatocyte nuclear factor 4 gamma
chr14_+_93927259 0.17 ENST00000556222.1
ENST00000554404.1
FAM181A
family with sequence similarity 181 member A
chr8_+_75539862 0.17 ENST00000396423.4
HNF4G
hepatocyte nuclear factor 4 gamma
chr7_-_128775793 0.16 ENST00000249389.3
OPN1SW
opsin 1, short wave sensitive
chr15_+_78507552 0.16 ENST00000408962.6
ENST00000388988.9
HYKK
hydroxylysine kinase
chr2_-_18560616 0.16 ENST00000381249.4
RDH14
retinol dehydrogenase 14
chr18_+_63907948 0.16 ENST00000238508.8
SERPINB10
serpin family B member 10
chr6_-_158819355 0.15 ENST00000367075.4
EZR
ezrin
chr8_-_71547626 0.15 ENST00000647540.1
ENST00000644229.1
EYA1
EYA transcriptional coactivator and phosphatase 1
chr7_-_27185223 0.15 ENST00000517402.1
ENST00000006015.4
HOXA11
homeobox A11
chr1_+_113929600 0.15 ENST00000369558.5
ENST00000369561.8
HIPK1
homeodomain interacting protein kinase 1
chr1_-_203182805 0.15 ENST00000404436.2
CHI3L1
chitinase 3 like 1
chr8_+_132866948 0.14 ENST00000220616.9
TG
thyroglobulin
chr19_-_42442938 0.14 ENST00000601181.6
CXCL17
C-X-C motif chemokine ligand 17
chr10_+_84424919 0.14 ENST00000543283.2
ENST00000494586.5
CCSER2
coiled-coil serine rich protein 2
chr12_+_93378550 0.14 ENST00000550056.5
ENST00000549992.5
ENST00000548662.5
ENST00000547014.5
NUDT4
nudix hydrolase 4
chr20_+_54475584 0.14 ENST00000262593.10
DOK5
docking protein 5
chr1_-_160070102 0.13 ENST00000638728.1
ENST00000637644.1
KCNJ10
potassium inwardly rectifying channel subfamily J member 10
chr5_+_79111802 0.13 ENST00000524080.1
ENST00000274353.10
BHMT
betaine--homocysteine S-methyltransferase
chr7_-_131556602 0.13 ENST00000322985.9
ENST00000378555.8
PODXL
podocalyxin like
chrY_+_14522573 0.13 ENST00000643089.1
ENST00000382872.5
NLGN4Y
neuroligin 4 Y-linked
chr8_-_94208548 0.12 ENST00000027335.8
ENST00000441892.6
ENST00000521491.1
CDH17
cadherin 17
chrX_+_11760087 0.12 ENST00000649271.1
MSL3
MSL complex subunit 3
chr17_-_31314066 0.12 ENST00000577894.1
EVI2B
ecotropic viral integration site 2B
chr4_-_167234266 0.12 ENST00000511269.5
ENST00000506697.5
ENST00000512042.1
SPOCK3
SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3
chr1_-_202889099 0.12 ENST00000367262.4
RABIF
RAB interacting factor
chr3_+_42160160 0.12 ENST00000341421.7
ENST00000396175.5
TRAK1
trafficking kinesin protein 1
chr2_-_24972032 0.12 ENST00000534855.5
DNAJC27
DnaJ heat shock protein family (Hsp40) member C27
chr2_-_175168159 0.12 ENST00000392544.5
ENST00000409499.5
ENST00000409833.5
ENST00000264110.7
ENST00000409635.5
ENST00000345739.9
ENST00000426833.7
ATF2
activating transcription factor 2
chr20_+_54475647 0.11 ENST00000395939.5
DOK5
docking protein 5
chr19_+_35106510 0.11 ENST00000648240.1
ENSG00000285526.1
novel protein
chr14_+_94174284 0.11 ENST00000304338.8
PPP4R4
protein phosphatase 4 regulatory subunit 4
chr7_-_139109702 0.11 ENST00000471652.1
ENST00000242351.10
ZC3HAV1
zinc finger CCCH-type containing, antiviral 1
chrX_+_11760035 0.11 ENST00000482871.6
ENST00000648013.1
MSL3
MSL complex subunit 3
chr1_+_19882374 0.11 ENST00000375120.4
OTUD3
OTU deubiquitinase 3
chr1_-_206970457 0.10 ENST00000324852.9
ENST00000450945.3
ENST00000400962.8
FCAMR
Fc fragment of IgA and IgM receptor
chr4_-_167234426 0.10 ENST00000541354.5
ENST00000509854.5
ENST00000512681.5
ENST00000357545.9
ENST00000510741.5
ENST00000510403.5
SPOCK3
SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3
chrX_-_49184789 0.10 ENST00000453382.5
ENST00000432913.5
PRICKLE3
prickle planar cell polarity protein 3
chr1_-_160070150 0.10 ENST00000644903.1
KCNJ10
potassium inwardly rectifying channel subfamily J member 10
chr20_-_44210697 0.10 ENST00000255174.3
OSER1
oxidative stress responsive serine rich 1
chr4_-_167234579 0.10 ENST00000502330.5
ENST00000357154.7
ENST00000421836.6
SPOCK3
SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3
chrX_-_50200988 0.09 ENST00000358526.7
AKAP4
A-kinase anchoring protein 4
chr15_+_73684731 0.09 ENST00000560995.5
CD276
CD276 molecule
chr16_+_69424634 0.09 ENST00000515314.6
ENST00000561792.6
ENST00000568237.1
CYB5B
cytochrome b5 type B
chr3_-_108222383 0.09 ENST00000264538.4
IFT57
intraflagellar transport 57
chr5_-_150412743 0.09 ENST00000353334.11
ENST00000009530.12
ENST00000377795.7
CD74
CD74 molecule
chr3_-_184378201 0.09 ENST00000647395.1
THPO
thrombopoietin
chr17_-_15341577 0.09 ENST00000543896.1
ENST00000395930.6
ENST00000539245.5
ENST00000539316.1
TEKT3
tektin 3
chr4_-_73988179 0.09 ENST00000296028.4
PPBP
pro-platelet basic protein
chr3_-_139539679 0.09 ENST00000483943.6
ENST00000672186.1
ENST00000232219.6
ENST00000617459.4
ENST00000492918.1
RBP1
retinol binding protein 1
chr17_-_7590072 0.09 ENST00000538513.6
ENST00000570788.1
ENST00000250055.3
SOX15
SRY-box transcription factor 15
chr12_-_51028234 0.09 ENST00000547688.7
ENST00000394904.9
SLC11A2
solute carrier family 11 member 2
chr17_-_69150062 0.09 ENST00000522787.5
ENST00000521538.5
ABCA10
ATP binding cassette subfamily A member 10
chr14_+_80955043 0.09 ENST00000541158.6
TSHR
thyroid stimulating hormone receptor
chr5_+_34929524 0.09 ENST00000648817.1
DNAJC21
DnaJ heat shock protein family (Hsp40) member C21
chr12_-_112382363 0.09 ENST00000682272.1
ENST00000377560.9
HECTD4
HECT domain E3 ubiquitin protein ligase 4
chr6_-_36442843 0.09 ENST00000454782.3
PXT1
peroxisomal testis enriched protein 1
chr2_-_179746040 0.08 ENST00000409343.5
ZNF385B
zinc finger protein 385B
chr6_+_31948956 0.08 ENST00000483004.1
CFB
complement factor B
chr19_+_55643592 0.08 ENST00000270451.6
ENST00000588537.1
ZNF581
zinc finger protein 581
chr15_+_78507605 0.08 ENST00000566332.5
HYKK
hydroxylysine kinase
chr20_+_34704336 0.08 ENST00000374809.6
ENST00000374810.8
ENST00000451665.5
TP53INP2
tumor protein p53 inducible nuclear protein 2
chr17_+_28728781 0.08 ENST00000268766.11
NEK8
NIMA related kinase 8
chr15_-_80989792 0.08 ENST00000261758.6
ENST00000561312.5
MESD
mesoderm development LRP chaperone
chr6_-_39322540 0.08 ENST00000425054.6
ENST00000373227.8
ENST00000373229.9
KCNK16
potassium two pore domain channel subfamily K member 16
chr6_-_93419545 0.08 ENST00000369297.1
ENST00000369303.9
ENST00000680224.1
ENST00000681532.1
ENST00000679565.1
EPHA7
EPH receptor A7
chr1_-_24930263 0.08 ENST00000308873.11
RUNX3
RUNX family transcription factor 3
chr15_-_74433942 0.07 ENST00000543145.6
ENST00000261918.9
SEMA7A
semaphorin 7A (John Milton Hagen blood group)
chr17_+_4932248 0.07 ENST00000329125.6
GP1BA
glycoprotein Ib platelet subunit alpha
chr17_-_10549652 0.07 ENST00000245503.10
MYH2
myosin heavy chain 2
chr12_+_4809176 0.07 ENST00000280684.3
KCNA6
potassium voltage-gated channel subfamily A member 6
chr1_+_159826860 0.07 ENST00000289707.10
SLAMF8
SLAM family member 8
chr4_-_167234552 0.07 ENST00000512648.5
SPOCK3
SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3
chr6_+_33410961 0.07 ENST00000374512.7
ENST00000374516.8
PHF1
PHD finger protein 1
chr4_+_80197493 0.07 ENST00000415738.3
PRDM8
PR/SET domain 8
chr3_-_108222362 0.07 ENST00000492106.1
IFT57
intraflagellar transport 57
chr6_-_41747390 0.07 ENST00000356667.8
ENST00000373025.7
ENST00000425343.6
PGC
progastricsin
chr6_+_29439939 0.07 ENST00000622521.1
OR10C1
olfactory receptor family 10 subfamily C member 1
chr17_-_10549612 0.07 ENST00000532183.6
ENST00000397183.6
ENST00000420805.1
MYH2
myosin heavy chain 2
chr7_+_100177743 0.07 ENST00000394018.6
ENST00000416412.5
STAG3
stromal antigen 3
chr7_+_100177897 0.07 ENST00000317296.9
ENST00000615138.5
ENST00000620100.5
ENST00000422690.5
ENST00000439782.1
STAG3
stromal antigen 3
chr11_+_26332117 0.07 ENST00000531646.1
ENST00000256737.8
ANO3
anoctamin 3
chr15_+_82809618 0.07 ENST00000286760.5
WHAMM
WASP homolog associated with actin, golgi membranes and microtubules
chr17_-_8376658 0.07 ENST00000643221.1
ENST00000647210.1
ENST00000649935.1
ENST00000396267.3
KRBA2
KRAB-A domain containing 2
chr20_+_33666932 0.06 ENST00000677665.1
ACTL10
actin like 10
chr17_-_10549694 0.06 ENST00000622564.4
MYH2
myosin heavy chain 2
chr15_+_42548810 0.06 ENST00000568876.5
ENST00000568846.6
ENST00000562398.5
ENST00000260372.8
HAUS2
HAUS augmin like complex subunit 2
chr2_-_24971900 0.06 ENST00000264711.7
DNAJC27
DnaJ heat shock protein family (Hsp40) member C27
chr17_+_68525795 0.06 ENST00000592800.5
PRKAR1A
protein kinase cAMP-dependent type I regulatory subunit alpha
chr19_+_16888991 0.06 ENST00000248076.4
F2RL3
F2R like thrombin or trypsin receptor 3
chr1_+_100351698 0.06 ENST00000644676.1
CDC14A
cell division cycle 14A
chr8_-_113436883 0.06 ENST00000455883.2
ENST00000297405.10
CSMD3
CUB and Sushi multiple domains 3
chr11_+_18599782 0.06 ENST00000634992.1
ENST00000635674.1
ENST00000511927.2
SPTY2D1OS
SPTY2D1 opposite strand
chr14_+_80955577 0.06 ENST00000642209.1
ENST00000298171.7
TSHR
thyroid stimulating hormone receptor
chr4_-_46993520 0.06 ENST00000264318.4
GABRA4
gamma-aminobutyric acid type A receptor subunit alpha4
chr10_-_100081854 0.05 ENST00000370418.8
CPN1
carboxypeptidase N subunit 1
chr4_-_143905529 0.05 ENST00000358615.9
ENST00000437468.2
GYPE
glycophorin E (MNS blood group)
chr4_-_46124046 0.05 ENST00000295452.5
GABRG1
gamma-aminobutyric acid type A receptor subunit gamma1
chr17_-_27893339 0.05 ENST00000460380.6
ENST00000379102.8
ENST00000508862.5
ENST00000582441.1
LYRM9
ENSG00000266202.1
LYR motif containing 9
novel protein
chr5_+_141350081 0.05 ENST00000523390.2
ENST00000611598.1
PCDHGB1
protocadherin gamma subfamily B, 1
chrX_-_84188148 0.05 ENST00000262752.5
RPS6KA6
ribosomal protein S6 kinase A6
chr7_-_81770039 0.04 ENST00000222390.11
ENST00000453411.6
ENST00000457544.7
ENST00000444829.7
HGF
hepatocyte growth factor
chr1_-_150010675 0.04 ENST00000417191.2
ENST00000581312.6
OTUD7B
OTU deubiquitinase 7B
chr2_-_201071579 0.04 ENST00000453765.5
ENST00000452799.5
ENST00000446678.5
ENST00000418596.7
ENST00000681958.1
FAM126B
family with sequence similarity 126 member B
chr7_-_14902743 0.04 ENST00000402815.6
DGKB
diacylglycerol kinase beta
chr16_+_8720706 0.04 ENST00000425191.6
ENST00000569156.5
ABAT
4-aminobutyrate aminotransferase
chr3_-_155745016 0.04 ENST00000460012.7
PLCH1
phospholipase C eta 1
chr19_-_10836195 0.04 ENST00000589638.1
ENST00000214869.7
TMED1
transmembrane p24 trafficking protein 1
chr1_+_1308714 0.04 ENST00000467712.1
PUSL1
pseudouridine synthase like 1
chr11_-_108593738 0.04 ENST00000525344.5
ENST00000265843.9
EXPH5
exophilin 5
chr1_-_11055820 0.04 ENST00000490101.1
SRM
spermidine synthase
chr17_-_13601901 0.04 ENST00000284110.2
HS3ST3A1
heparan sulfate-glucosamine 3-sulfotransferase 3A1
chr15_+_90265634 0.04 ENST00000379095.5
NGRN
neugrin, neurite outgrowth associated
chr20_-_290364 0.04 ENST00000382369.9
C20orf96
chromosome 20 open reading frame 96
chr14_-_21048431 0.04 ENST00000555026.5
NDRG2
NDRG family member 2
chr10_-_126670686 0.04 ENST00000488181.3
C10orf90
chromosome 10 open reading frame 90
chr11_+_43680686 0.04 ENST00000531185.5
ENST00000278353.10
HSD17B12
hydroxysteroid 17-beta dehydrogenase 12
chr1_-_159925496 0.04 ENST00000368097.9
TAGLN2
transgelin 2
chr1_-_11847772 0.04 ENST00000376480.7
ENST00000610706.1
NPPA
natriuretic peptide A
chr17_-_58544315 0.04 ENST00000671766.1
ENST00000672673.2
ENST00000321691.3
SEPTIN4
septin 4
chr4_+_152779934 0.03 ENST00000451320.6
ENST00000429148.6
ENST00000353617.7
ENST00000405727.6
ENST00000356064.3
ARFIP1
ADP ribosylation factor interacting protein 1
chr7_+_142749465 0.03 ENST00000486171.5
ENST00000619214.4
ENST00000311737.12
PRSS1
serine protease 1
chr20_-_290717 0.03 ENST00000360321.7
ENST00000400269.4
C20orf96
chromosome 20 open reading frame 96
chr5_+_55851378 0.03 ENST00000396836.6
ENST00000359040.10
IL31RA
interleukin 31 receptor A
chr19_-_51082883 0.03 ENST00000650543.2
KLK14
kallikrein related peptidase 14
chr3_-_149657996 0.03 ENST00000360632.8
ENST00000467467.5
ENST00000460517.1
WWTR1
WW domain containing transcription regulator 1
chr3_-_149377637 0.03 ENST00000305366.8
TM4SF1
transmembrane 4 L six family member 1
chr5_+_55851349 0.03 ENST00000652347.2
IL31RA
interleukin 31 receptor A
chr1_+_113905290 0.03 ENST00000650450.2
DCLRE1B
DNA cross-link repair 1B
chr2_-_151261839 0.03 ENST00000331426.6
RBM43
RNA binding motif protein 43
chrX_-_143635081 0.03 ENST00000338017.8
SLITRK4
SLIT and NTRK like family member 4
chr11_+_99020940 0.03 ENST00000524871.6
CNTN5
contactin 5
chr2_-_85668172 0.03 ENST00000428225.5
ENST00000519937.7
SFTPB
surfactant protein B
chrX_+_14529516 0.03 ENST00000218075.9
GLRA2
glycine receptor alpha 2
chrX_-_109733249 0.03 ENST00000469796.7
ENST00000672401.1
ENST00000671846.1
ACSL4
acyl-CoA synthetase long chain family member 4
chr17_+_47896150 0.03 ENST00000642065.1
ENST00000613139.1
ENST00000637314.1
ENST00000637943.1
ENST00000376741.5
ENST00000635868.1
SP2
Sp2 transcription factor
chr17_-_59964714 0.03 ENST00000589113.1
ENST00000305783.13
RNFT1
ring finger protein, transmembrane 1
chr16_+_77199408 0.03 ENST00000378644.5
SYCE1L
synaptonemal complex central element protein 1 like
chr2_-_166149120 0.02 ENST00000641575.1
ENST00000641603.1
SCN1A
sodium voltage-gated channel alpha subunit 1
chr11_-_19201976 0.02 ENST00000647990.1
ENST00000649235.1
ENST00000265968.9
ENST00000649842.1
CSRP3
cysteine and glycine rich protein 3
chr17_+_60677822 0.02 ENST00000407086.8
ENST00000589222.5
ENST00000626960.2
ENST00000390652.9
BCAS3
BCAS3 microtubule associated cell migration factor
chr2_-_166149204 0.02 ENST00000635750.1
SCN1A
sodium voltage-gated channel alpha subunit 1
chr14_+_23185316 0.02 ENST00000399910.5
ENST00000492621.5
RNF212B
ring finger protein 212B
chrX_-_109733292 0.02 ENST00000682031.1
ENST00000502391.6
ENST00000508092.5
ENST00000348502.10
ACSL4
acyl-CoA synthetase long chain family member 4
chrX_-_109733220 0.02 ENST00000672282.1
ENST00000340800.7
ACSL4
acyl-CoA synthetase long chain family member 4
chr22_-_50085414 0.02 ENST00000311597.10
MLC1
modulator of VRAC current 1
chr7_+_129368123 0.02 ENST00000460109.5
ENST00000474594.5
AHCYL2
adenosylhomocysteinase like 2
chr1_-_101996919 0.02 ENST00000370103.9
OLFM3
olfactomedin 3
chr6_+_29587455 0.02 ENST00000383640.4
OR2H2
olfactory receptor family 2 subfamily H member 2
chr19_-_38388020 0.02 ENST00000334928.11
ENST00000587676.1
GGN
gametogenetin
chr3_-_177197429 0.02 ENST00000457928.7
TBL1XR1
TBL1X receptor 1
chr17_+_55264952 0.02 ENST00000226067.10
HLF
HLF transcription factor, PAR bZIP family member
chr19_+_14562356 0.02 ENST00000596073.6
TECR
trans-2,3-enoyl-CoA reductase
chr3_+_179653129 0.02 ENST00000680008.1
USP13
ubiquitin specific peptidase 13
chr16_+_81651186 0.02 ENST00000566462.2
CMIP
c-Maf inducing protein
chr3_+_179653032 0.01 ENST00000680587.1
ENST00000681064.1
ENST00000263966.8
ENST00000681358.1
ENST00000679749.1
USP13
ubiquitin specific peptidase 13
chr3_+_125969152 0.01 ENST00000251776.8
ENST00000504401.1
ROPN1B
rhophilin associated tail protein 1B
chr8_+_86866415 0.01 ENST00000518476.6
CNBD1
cyclic nucleotide binding domain containing 1
chr14_+_80955366 0.01 ENST00000342443.10
TSHR
thyroid stimulating hormone receptor
chr3_-_113696624 0.01 ENST00000316407.9
ENST00000491165.5
USF3
upstream transcription factor family member 3
chr1_+_161721563 0.01 ENST00000367948.6
FCRLB
Fc receptor like B
chr10_-_79560386 0.01 ENST00000372327.9
ENST00000417041.1
ENST00000640627.1
ENST00000372325.7
SFTPA2
surfactant protein A2
chr22_+_38057200 0.01 ENST00000404072.7
ENST00000424694.5
PICK1
protein interacting with PRKCA 1
chr13_-_72727600 0.01 ENST00000377818.4
MZT1
mitotic spindle organizing protein 1
chr22_-_50085331 0.01 ENST00000395876.6
MLC1
modulator of VRAC current 1
chr19_-_48170323 0.01 ENST00000263274.12
ENST00000427526.6
LIG1
DNA ligase 1
chr9_-_25678375 0.01 ENST00000358022.6
TUSC1
tumor suppressor candidate 1
chr11_+_118883884 0.01 ENST00000292174.5
CXCR5
C-X-C motif chemokine receptor 5
chr10_+_103245887 0.01 ENST00000441178.2
RPEL1
ribulose-5-phosphate-3-epimerase like 1
chr17_-_42017345 0.01 ENST00000674411.1
DNAJC7
DnaJ heat shock protein family (Hsp40) member C7

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.1 0.4 GO:1901909 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.0 0.2 GO:0051935 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.0 0.1 GO:0006579 amino-acid betaine catabolic process(GO:0006579)
0.0 0.1 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.0 0.2 GO:0009730 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0 0.2 GO:1905229 cellular response to glycoprotein(GO:1904588) cellular response to thyrotropin-releasing hormone(GO:1905229)
0.0 0.2 GO:0033490 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.0 0.2 GO:0045204 MAPK export from nucleus(GO:0045204)
0.0 0.1 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.0 0.1 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.0 0.2 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.0 0.2 GO:1902896 terminal web assembly(GO:1902896)
0.0 0.1 GO:0002901 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906) macrophage migration inhibitory factor signaling pathway(GO:0035691)
0.0 0.1 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
0.0 0.1 GO:0098957 anterograde axonal transport of mitochondrion(GO:0098957)
0.0 0.8 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.0 0.2 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.0 0.4 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.6 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.4 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.1 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 0.1 GO:0015705 iodide transport(GO:0015705)
0.0 0.1 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
0.0 0.1 GO:0080154 regulation of fertilization(GO:0080154)
0.0 0.1 GO:0015692 lead ion transport(GO:0015692)
0.0 0.3 GO:0033327 Leydig cell differentiation(GO:0033327)
0.0 0.2 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.3 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.0 0.1 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.0 0.2 GO:0006554 lysine catabolic process(GO:0006554)
0.0 0.1 GO:0002803 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antibacterial peptide production(GO:0002803)
0.0 0.2 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.4 GO:0030728 ovulation(GO:0030728)
0.0 0.1 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.1 GO:0030070 insulin processing(GO:0030070)
0.0 0.4 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.1 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.0 GO:1904450 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450)
0.0 0.1 GO:0032906 transforming growth factor beta2 production(GO:0032906) regulation of transforming growth factor beta2 production(GO:0032909)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0072487 MSL complex(GO:0072487)
0.0 0.2 GO:0044393 microspike(GO:0044393) cytoplasmic side of apical plasma membrane(GO:0098592)
0.0 0.2 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.1 GO:0097543 ciliary inversin compartment(GO:0097543)
0.0 0.2 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.3 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.1 GO:0070826 paraferritin complex(GO:0070826)
0.0 0.1 GO:0030893 meiotic cohesin complex(GO:0030893)
0.0 0.2 GO:0044292 dendrite terminus(GO:0044292)
0.0 0.0 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.1 0.4 GO:0052840 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.0 0.2 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.0 0.2 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.2 GO:0019158 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.1 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.0 0.2 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.2 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.0 0.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.4 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.2 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 0.1 GO:0015094 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.0 0.1 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.0 0.3 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.1 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.0 GO:0004766 spermidine synthase activity(GO:0004766)
0.0 0.1 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.2 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.1 GO:0004568 chitinase activity(GO:0004568)
0.0 0.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.0 GO:0032145 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.0 0.4 GO:0005540 hyaluronic acid binding(GO:0005540)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 ST JNK MAPK PATHWAY JNK MAPK Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.4 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.2 REACTOME OPSINS Genes involved in Opsins
0.0 0.2 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.5 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.2 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors