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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for NKX2-8

Z-value: 0.58

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Transcription factors associated with NKX2-8

Gene Symbol Gene ID Gene Info
NKX2-8
ENSG00000136327.7 NKX2-8

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NKX2-8hg38_v1_chr14_-_36582593_36582626-0.311.3e-01Click!

Activity profile of NKX2-8 motif

Sorted Z-values of NKX2-8 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of NKX2-8

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr17_-_3691887 0.78 ENST00000552050.5
P2RX5
purinergic receptor P2X 5
chr17_-_69150062 0.51 ENST00000522787.5
ENST00000521538.5
ABCA10
ATP binding cassette subfamily A member 10
chr11_+_5389377 0.46 ENST00000328611.5
OR51M1
olfactory receptor family 51 subfamily M member 1
chr1_+_172420681 0.44 ENST00000367727.9
C1orf105
chromosome 1 open reading frame 105
chr1_+_74235377 0.44 ENST00000326637.8
TNNI3K
TNNI3 interacting kinase
chr14_-_106875069 0.41 ENST00000390639.2
IGHV7-81
immunoglobulin heavy variable 7-81 (non-functional)
chr3_+_111998739 0.40 ENST00000393917.6
ENST00000273368.8
TAGLN3
transgelin 3
chr3_+_111998915 0.38 ENST00000478951.6
TAGLN3
transgelin 3
chr16_-_68015911 0.36 ENST00000574912.1
DPEP2NB
DPEP2 neighbor
chr10_-_73641450 0.36 ENST00000359322.5
MYOZ1
myozenin 1
chr2_+_227616998 0.32 ENST00000641801.1
SCYGR4
small cysteine and glycine repeat containing 4
chr3_+_126704202 0.32 ENST00000290913.8
ENST00000508789.5
CHCHD6
coiled-coil-helix-coiled-coil-helix domain containing 6
chr14_-_106675544 0.32 ENST00000390632.2
IGHV3-66
immunoglobulin heavy variable 3-66
chr6_+_29439939 0.29 ENST00000622521.1
OR10C1
olfactory receptor family 10 subfamily C member 1
chrX_-_111410420 0.29 ENST00000371993.7
ENST00000680476.1
DCX
doublecortin
chr22_+_31122923 0.28 ENST00000620191.4
ENST00000412277.6
ENST00000412985.5
ENST00000331075.10
ENST00000420017.5
ENST00000400294.6
ENST00000405300.5
ENST00000404390.7
INPP5J
inositol polyphosphate-5-phosphatase J
chr14_-_63318933 0.28 ENST00000621500.2
GPHB5
glycoprotein hormone subunit beta 5
chr8_-_143568854 0.28 ENST00000524906.5
ENST00000532862.1
ENST00000534459.5
MROH6
maestro heat like repeat family member 6
chr19_-_48993300 0.28 ENST00000323798.8
ENST00000263276.6
GYS1
glycogen synthase 1
chr11_-_72642407 0.28 ENST00000376450.7
PDE2A
phosphodiesterase 2A
chr11_-_72642450 0.28 ENST00000444035.6
ENST00000544570.5
PDE2A
phosphodiesterase 2A
chr1_-_155033778 0.27 ENST00000368424.4
DCST2
DC-STAMP domain containing 2
chr4_+_71062642 0.26 ENST00000649996.1
SLC4A4
solute carrier family 4 member 4
chr10_-_13972355 0.26 ENST00000264546.10
FRMD4A
FERM domain containing 4A
chr6_+_28525877 0.26 ENST00000412168.7
GPX5
glutathione peroxidase 5
chr11_-_19202004 0.25 ENST00000648719.1
CSRP3
cysteine and glycine rich protein 3
chr3_-_52154382 0.25 ENST00000474012.1
ENST00000296484.7
POC1A
POC1 centriolar protein A
chr11_-_107719657 0.25 ENST00000525934.1
ENST00000531293.1
SLN
sarcolipin
chr14_-_58427509 0.25 ENST00000395159.7
TIMM9
translocase of inner mitochondrial membrane 9
chrX_+_153687918 0.25 ENST00000253122.10
SLC6A8
solute carrier family 6 member 8
chr14_-_106593319 0.24 ENST00000390627.3
IGHV3-53
immunoglobulin heavy variable 3-53
chr2_+_86441341 0.24 ENST00000312912.10
ENST00000409064.5
KDM3A
lysine demethylase 3A
chr12_-_262828 0.24 ENST00000343164.9
ENST00000436453.1
ENST00000445055.6
ENST00000546319.5
SLC6A13
solute carrier family 6 member 13
chr22_-_36817510 0.24 ENST00000443735.1
PVALB
parvalbumin
chr12_-_12684490 0.23 ENST00000540510.1
GPR19
G protein-coupled receptor 19
chr3_+_66998297 0.23 ENST00000484414.5
ENST00000460576.5
ENST00000417314.2
KBTBD8
kelch repeat and BTB domain containing 8
chr7_+_75398915 0.23 ENST00000437796.1
TRIM73
tripartite motif containing 73
chr10_+_17752185 0.23 ENST00000377495.2
TMEM236
transmembrane protein 236
chr15_+_45129933 0.22 ENST00000321429.8
ENST00000389037.7
ENST00000558322.5
DUOX1
dual oxidase 1
chr3_+_186666003 0.22 ENST00000232003.5
HRG
histidine rich glycoprotein
chrX_-_70260199 0.22 ENST00000374519.4
P2RY4
pyrimidinergic receptor P2Y4
chr18_+_46917561 0.21 ENST00000683218.1
KATNAL2
katanin catalytic subunit A1 like 2
chr8_+_42338454 0.21 ENST00000532157.5
ENST00000520008.5
POLB
DNA polymerase beta
chr6_+_69232406 0.21 ENST00000238918.12
ADGRB3
adhesion G protein-coupled receptor B3
chr12_-_117968972 0.20 ENST00000339824.7
KSR2
kinase suppressor of ras 2
chr6_+_147508645 0.19 ENST00000367474.2
SAMD5
sterile alpha motif domain containing 5
chr2_+_232633551 0.19 ENST00000264059.8
EFHD1
EF-hand domain family member D1
chr9_+_35909481 0.19 ENST00000443779.3
SPAAR
small regulatory polypeptide of amino acid response
chr9_+_35910076 0.19 ENST00000636776.1
SPAAR
small regulatory polypeptide of amino acid response
chr3_+_51538684 0.19 ENST00000684192.1
RAD54L2
RAD54 like 2
chr17_+_75476493 0.18 ENST00000375248.9
TMEM94
transmembrane protein 94
chr15_+_40161003 0.18 ENST00000412359.7
ENST00000287598.11
BUB1B
BUB1 mitotic checkpoint serine/threonine kinase B
chr17_+_78214286 0.18 ENST00000592734.5
ENST00000587746.5
BIRC5
baculoviral IAP repeat containing 5
chr2_-_158456702 0.18 ENST00000409889.1
ENST00000283233.10
CCDC148
coiled-coil domain containing 148
chr17_+_78214186 0.18 ENST00000301633.8
ENST00000350051.8
ENST00000374948.6
ENST00000590449.1
BIRC5
baculoviral IAP repeat containing 5
chr10_+_69318831 0.18 ENST00000359426.7
HK1
hexokinase 1
chr5_-_79512794 0.17 ENST00000282260.10
ENST00000508576.5
ENST00000535690.1
HOMER1
homer scaffold protein 1
chr4_+_75556048 0.17 ENST00000616557.1
ENST00000435974.2
ENST00000311623.9
ODAPH
odontogenesis associated phosphoprotein
chr11_+_35189869 0.17 ENST00000525688.5
ENST00000278385.10
ENST00000533222.5
CD44
CD44 molecule (Indian blood group)
chrX_-_130385656 0.16 ENST00000276218.4
ENST00000682440.1
GPR119
G protein-coupled receptor 119
chr5_-_102498913 0.16 ENST00000513675.1
ENST00000379807.7
ENST00000506729.6
SLCO6A1
solute carrier organic anion transporter family member 6A1
chr19_+_34365173 0.16 ENST00000589640.5
ENST00000591204.5
ENST00000589399.6
ENST00000356487.11
GPI
glucose-6-phosphate isomerase
chr4_-_169270849 0.16 ENST00000502315.1
ENST00000284637.14
SH3RF1
SH3 domain containing ring finger 1
chr3_-_196515315 0.16 ENST00000397537.3
SMCO1
single-pass membrane protein with coiled-coil domains 1
chr17_-_33293247 0.16 ENST00000225823.7
ASIC2
acid sensing ion channel subunit 2
chr22_+_29438583 0.16 ENST00000354373.2
RFPL1
ret finger protein like 1
chr15_-_74956758 0.16 ENST00000322177.6
RPP25
ribonuclease P and MRP subunit p25
chr5_-_102499008 0.16 ENST00000389019.7
SLCO6A1
solute carrier organic anion transporter family member 6A1
chrX_-_64230600 0.16 ENST00000362002.3
ASB12
ankyrin repeat and SOCS box containing 12
chr4_+_177309866 0.16 ENST00000264596.4
NEIL3
nei like DNA glycosylase 3
chr2_+_27496830 0.15 ENST00000264717.7
GCKR
glucokinase regulator
chr20_-_49913693 0.15 ENST00000422556.1
SPATA2
spermatogenesis associated 2
chr11_-_19201976 0.15 ENST00000647990.1
ENST00000649235.1
ENST00000265968.9
ENST00000649842.1
CSRP3
cysteine and glycine rich protein 3
chr12_+_7789393 0.15 ENST00000229307.9
NANOG
Nanog homeobox
chr1_-_27672178 0.15 ENST00000339145.8
ENST00000361157.11
ENST00000362020.4
ENST00000679644.1
IFI6
interferon alpha inducible protein 6
chr14_-_106211453 0.15 ENST00000390606.3
IGHV3-20
immunoglobulin heavy variable 3-20
chr17_+_78231310 0.14 ENST00000374946.7
ENST00000421688.5
ENST00000586400.5
TMEM235
transmembrane protein 235
chr22_+_38705922 0.14 ENST00000216044.10
GTPBP1
GTP binding protein 1
chr3_-_115071333 0.14 ENST00000462705.5
ZBTB20
zinc finger and BTB domain containing 20
chr17_-_8295342 0.14 ENST00000579192.5
ENST00000577745.2
SLC25A35
solute carrier family 25 member 35
chr10_-_99913971 0.14 ENST00000543621.6
DNMBP
dynamin binding protein
chr14_-_106130061 0.14 ENST00000390602.3
IGHV3-13
immunoglobulin heavy variable 3-13
chr15_-_34754989 0.14 ENST00000290374.5
GJD2
gap junction protein delta 2
chr11_-_114595750 0.14 ENST00000424261.6
NXPE4
neurexophilin and PC-esterase domain family member 4
chr4_-_99563984 0.13 ENST00000394877.7
TRMT10A
tRNA methyltransferase 10A
chr4_-_99564026 0.13 ENST00000394876.7
TRMT10A
tRNA methyltransferase 10A
chr2_-_29074515 0.13 ENST00000331664.6
PCARE
photoreceptor cilium actin regulator
chr11_-_64246190 0.13 ENST00000392210.6
PPP1R14B
protein phosphatase 1 regulatory inhibitor subunit 14B
chr12_-_75209814 0.13 ENST00000549446.6
KCNC2
potassium voltage-gated channel subfamily C member 2
chr6_+_125203639 0.13 ENST00000392482.6
TPD52L1
TPD52 like 1
chr6_+_96563117 0.12 ENST00000450218.6
FHL5
four and a half LIM domains 5
chr14_+_58427385 0.12 ENST00000354386.10
ENST00000619416.4
KIAA0586
KIAA0586
chrX_+_48823357 0.12 ENST00000430858.1
HDAC6
histone deacetylase 6
chr11_-_132943671 0.12 ENST00000331898.11
OPCML
opioid binding protein/cell adhesion molecule like
chr9_-_21166660 0.12 ENST00000380225.1
IFNA21
interferon alpha 21
chr16_+_33827140 0.12 ENST00000562905.2
IGHV3OR16-13
immunoglobulin heavy variable 3/OR16-13 (non-functional)
chr14_+_58298497 0.12 ENST00000348476.7
ENST00000355431.8
ENST00000395168.7
ARID4A
AT-rich interaction domain 4A
chr14_-_58427158 0.12 ENST00000555097.1
ENST00000556367.6
ENST00000555404.5
TIMM9
translocase of inner mitochondrial membrane 9
chr12_+_25052732 0.12 ENST00000547044.5
IRAG2
inositol 1,4,5-triphosphate receptor associated 2
chr14_-_58427489 0.11 ENST00000555593.5
TIMM9
translocase of inner mitochondrial membrane 9
chr6_-_2744126 0.11 ENST00000647417.1
MYLK4
myosin light chain kinase family member 4
chr16_+_32995048 0.11 ENST00000425181.3
IGHV3OR16-10
immunoglobulin heavy variable 3/OR16-10 (non-functional)
chr1_+_151540299 0.11 ENST00000392712.7
ENST00000368848.6
ENST00000368849.8
ENST00000353024.4
TUFT1
tuftelin 1
chr8_-_144465648 0.11 ENST00000424149.6
ENST00000530637.1
CYHR1
cysteine and histidine rich 1
chr14_+_21887848 0.11 ENST00000390437.2
TRAV12-2
T cell receptor alpha variable 12-2
chr8_-_123396412 0.11 ENST00000287394.10
ATAD2
ATPase family AAA domain containing 2
chr14_+_58427686 0.11 ENST00000650904.1
ENST00000652326.2
ENST00000554463.5
ENST00000555833.5
KIAA0586
KIAA0586
chr2_-_166149120 0.11 ENST00000641575.1
ENST00000641603.1
SCN1A
sodium voltage-gated channel alpha subunit 1
chr7_+_151232464 0.11 ENST00000482173.5
ENST00000495645.5
ENST00000035307.6
CHPF2
chondroitin polymerizing factor 2
chr5_-_176629943 0.11 ENST00000510387.5
ENST00000506696.1
SNCB
synuclein beta
chr7_+_130207847 0.11 ENST00000297819.4
SSMEM1
serine rich single-pass membrane protein 1
chr12_+_25052512 0.11 ENST00000557489.5
ENST00000354454.7
ENST00000536173.5
IRAG2
inositol 1,4,5-triphosphate receptor associated 2
chr11_-_132943092 0.11 ENST00000612177.4
ENST00000541867.5
OPCML
opioid binding protein/cell adhesion molecule like
chr7_-_157010615 0.11 ENST00000252971.11
MNX1
motor neuron and pancreas homeobox 1
chr16_+_58392462 0.11 ENST00000318129.6
GINS3
GINS complex subunit 3
chr3_+_63967738 0.11 ENST00000484332.1
ATXN7
ataxin 7
chr11_-_40293102 0.10 ENST00000527150.5
LRRC4C
leucine rich repeat containing 4C
chr14_+_58427970 0.10 ENST00000261244.9
KIAA0586
KIAA0586
chr7_-_36724380 0.10 ENST00000617267.4
AOAH
acyloxyacyl hydrolase
chr2_+_79025696 0.10 ENST00000272324.10
REG3G
regenerating family member 3 gamma
chr16_-_75267988 0.10 ENST00000393422.6
BCAR1
BCAR1 scaffold protein, Cas family member
chr2_+_79025678 0.10 ENST00000393897.6
REG3G
regenerating family member 3 gamma
chr14_+_93927358 0.10 ENST00000557000.2
FAM181A
family with sequence similarity 181 member A
chr22_+_20858999 0.10 ENST00000215730.12
SNAP29
synaptosome associated protein 29
chr1_-_11055820 0.10 ENST00000490101.1
SRM
spermidine synthase
chr20_+_63738270 0.10 ENST00000467211.1
ENSG00000273047.1
novel transcript, LIME1-SLC2A4RG readthrough
chr6_-_32763466 0.10 ENST00000427449.1
ENST00000411527.5
HLA-DQB2
major histocompatibility complex, class II, DQ beta 2
chr3_-_53130405 0.10 ENST00000467048.1
ENST00000296292.8
ENST00000394738.7
RFT1
RFT1 homolog
chr14_-_55027045 0.10 ENST00000455555.1
ENST00000360586.8
ENST00000420358.2
WDHD1
WD repeat and HMG-box DNA binding protein 1
chrX_-_31178220 0.10 ENST00000681026.1
DMD
dystrophin
chr14_-_106389858 0.10 ENST00000390617.2
IGHV3-35
immunoglobulin heavy variable 3-35 (non-functional)
chr14_+_58427425 0.10 ENST00000619722.5
ENST00000423743.7
KIAA0586
KIAA0586
chr18_+_31591869 0.10 ENST00000237014.8
TTR
transthyretin
chr12_+_25052634 0.10 ENST00000548766.5
IRAG2
inositol 1,4,5-triphosphate receptor associated 2
chr16_+_78202 0.10 ENST00000356432.8
ENST00000219431.4
MPG
N-methylpurine DNA glycosylase
chr4_-_99563668 0.10 ENST00000273962.7
TRMT10A
tRNA methyltransferase 10A
chr3_-_39051935 0.10 ENST00000668754.1
ENST00000302328.9
SCN11A
sodium voltage-gated channel alpha subunit 11
chr14_-_106791226 0.10 ENST00000433072.2
IGHV3-72
immunoglobulin heavy variable 3-72
chr13_+_108269629 0.09 ENST00000430559.5
ENST00000375887.9
TNFSF13B
TNF superfamily member 13b
chr12_-_49110840 0.09 ENST00000550137.5
ENST00000267102.13
ENST00000547382.5
LMBR1L
limb development membrane protein 1 like
chrX_-_31178149 0.09 ENST00000679437.1
DMD
dystrophin
chr12_+_120978686 0.09 ENST00000541395.5
ENST00000544413.2
HNF1A
HNF1 homeobox A
chr1_+_180196536 0.09 ENST00000443059.1
QSOX1
quiescin sulfhydryl oxidase 1
chr10_-_77637789 0.09 ENST00000481070.1
ENST00000640969.1
ENST00000286628.14
ENST00000638991.1
ENST00000639913.1
ENST00000480683.2
KCNMA1
potassium calcium-activated channel subfamily M alpha 1
chr10_-_133357674 0.09 ENST00000368551.1
FUOM
fucose mutarotase
chr3_+_173584433 0.09 ENST00000361589.8
NLGN1
neuroligin 1
chr14_-_106235582 0.09 ENST00000390607.2
IGHV3-21
immunoglobulin heavy variable 3-21
chr1_+_149899618 0.09 ENST00000369150.1
BOLA1
bolA family member 1
chr2_+_218672027 0.09 ENST00000392105.7
ENST00000455724.5
ENST00000295709.8
STK36
serine/threonine kinase 36
chr7_-_36724543 0.09 ENST00000612871.4
AOAH
acyloxyacyl hydrolase
chr6_+_34466059 0.09 ENST00000620693.4
ENST00000244458.7
ENST00000374043.6
PACSIN1
protein kinase C and casein kinase substrate in neurons 1
chr1_+_173824626 0.08 ENST00000648960.1
ENST00000648807.1
ENST00000649067.1
ENST00000649689.2
DARS2
aspartyl-tRNA synthetase 2, mitochondrial
chr14_-_106269133 0.08 ENST00000390609.3
IGHV3-23
immunoglobulin heavy variable 3-23
chr5_+_69369781 0.08 ENST00000509734.5
ENST00000354868.10
ENST00000521422.5
ENST00000354312.7
ENST00000345306.10
RAD17
RAD17 checkpoint clamp loader component
chr15_-_28174423 0.08 ENST00000569772.1
HERC2
HECT and RLD domain containing E3 ubiquitin protein ligase 2
chr19_-_43754901 0.08 ENST00000270066.11
ENST00000601170.5
SMG9
SMG9 nonsense mediated mRNA decay factor
chr22_+_32357867 0.08 ENST00000249007.4
RFPL3
ret finger protein like 3
chr1_-_23424618 0.08 ENST00000476978.2
TCEA3
transcription elongation factor A3
chr21_+_32298945 0.08 ENST00000339944.4
MRAP
melanocortin 2 receptor accessory protein
chr7_-_36724457 0.08 ENST00000617537.5
ENST00000435386.1
AOAH
acyloxyacyl hydrolase
chr1_+_225825346 0.08 ENST00000366837.5
EPHX1
epoxide hydrolase 1
chr6_-_39322968 0.08 ENST00000507712.5
KCNK16
potassium two pore domain channel subfamily K member 16
chr10_-_77637721 0.08 ENST00000638848.1
ENST00000639406.1
ENST00000618048.2
ENST00000639120.1
ENST00000640834.1
ENST00000639601.1
ENST00000638514.1
ENST00000457953.6
ENST00000639090.1
ENST00000639489.1
ENST00000372440.6
ENST00000404771.8
ENST00000638203.1
ENST00000638306.1
ENST00000638351.1
ENST00000638606.1
ENST00000639591.1
ENST00000640182.1
ENST00000640605.1
ENST00000640141.1
KCNMA1
potassium calcium-activated channel subfamily M alpha 1
chr3_-_16482850 0.08 ENST00000432519.5
RFTN1
raftlin, lipid raft linker 1
chr1_-_204166334 0.08 ENST00000272190.9
REN
renin
chr3_+_109136707 0.08 ENST00000622536.6
C3orf85
chromosome 3 open reading frame 85
chr1_+_173824694 0.08 ENST00000647645.1
DARS2
aspartyl-tRNA synthetase 2, mitochondrial
chr19_+_39342396 0.08 ENST00000602243.5
ENST00000598913.5
ENST00000314471.10
SAMD4B
sterile alpha motif domain containing 4B
chrX_-_32155462 0.07 ENST00000359836.5
ENST00000378707.7
ENST00000541735.5
ENST00000684130.1
ENST00000682238.1
ENST00000620040.5
ENST00000474231.5
DMD
dystrophin
chr6_+_116461364 0.07 ENST00000368606.7
ENST00000368605.3
CALHM6
calcium homeostasis modulator family member 6
chr14_-_106470788 0.07 ENST00000434710.1
IGHV3-43
immunoglobulin heavy variable 3-43
chr20_-_50131125 0.07 ENST00000371656.3
PEDS1
plasmanylethanolamine desaturase 1
chr4_+_15339818 0.07 ENST00000397700.6
ENST00000295297.4
C1QTNF7
C1q and TNF related 7
chr7_-_95396349 0.07 ENST00000427422.5
ENST00000451904.5
ENST00000265627.10
PON3
paraoxonase 3
chr11_+_925840 0.06 ENST00000448903.7
ENST00000525796.5
ENST00000534328.5
AP2A2
adaptor related protein complex 2 subunit alpha 2
chr2_-_105438503 0.06 ENST00000393352.7
ENST00000607522.1
FHL2
four and a half LIM domains 2
chr3_-_179266971 0.06 ENST00000349697.2
ENST00000497599.5
KCNMB3
potassium calcium-activated channel subfamily M regulatory beta subunit 3
chr16_+_58392391 0.06 ENST00000426538.6
ENST00000328514.11
GINS3
GINS complex subunit 3
chr21_+_32298849 0.06 ENST00000303645.10
MRAP
melanocortin 2 receptor accessory protein
chr19_-_4559663 0.06 ENST00000586582.6
SEMA6B
semaphorin 6B
chr1_+_152985231 0.06 ENST00000368762.1
SPRR1A
small proline rich protein 1A
chr16_+_176659 0.06 ENST00000320868.9
ENST00000397797.1
HBA1
hemoglobin subunit alpha 1
chr10_+_72893734 0.06 ENST00000334011.10
OIT3
oncoprotein induced transcript 3
chr14_-_106538331 0.06 ENST00000390624.3
IGHV3-48
immunoglobulin heavy variable 3-48
chr20_+_33031648 0.06 ENST00000349552.1
BPIFB6
BPI fold containing family B member 6
chr22_-_50085331 0.06 ENST00000395876.6
MLC1
modulator of VRAC current 1
chr1_+_16022030 0.06 ENST00000331433.5
CLCNKA
chloride voltage-gated channel Ka
chr1_-_56966133 0.05 ENST00000535057.5
ENST00000543257.5
C8B
complement C8 beta chain
chr16_+_172869 0.05 ENST00000251595.11
ENST00000397806.1
ENST00000484216.1
HBA2
hemoglobin subunit alpha 2
chr12_-_6493295 0.05 ENST00000540949.1
MRPL51
mitochondrial ribosomal protein L51
chr2_-_218671975 0.05 ENST00000295704.7
RNF25
ring finger protein 25
chr14_+_63761836 0.05 ENST00000674003.1
SYNE2
spectrin repeat containing nuclear envelope protein 2
chr4_+_70334963 0.05 ENST00000273936.6
CABS1
calcium binding protein, spermatid associated 1
chr16_+_22490337 0.05 ENST00000415833.6
NPIPB5
nuclear pore complex interacting protein family member B5
chr2_-_63588390 0.05 ENST00000272321.12
ENST00000409562.7
WDPCP
WD repeat containing planar cell polarity effector
chr3_-_114624193 0.05 ENST00000481632.5
ZBTB20
zinc finger and BTB domain containing 20
chr14_-_106811131 0.05 ENST00000424969.2
IGHV3-74
immunoglobulin heavy variable 3-74
chr17_+_7688427 0.05 ENST00000396463.7
ENST00000534050.5
WRAP53
WD repeat containing antisense to TP53
chr8_+_39934955 0.05 ENST00000502986.2
IDO2
indoleamine 2,3-dioxygenase 2
chr12_+_49265071 0.05 ENST00000549183.1
ENST00000639419.1
ENST00000301072.11
TUBA1C
tubulin alpha 1c

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
0.1 0.3 GO:1901876 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.1 0.2 GO:0046292 formaldehyde metabolic process(GO:0046292)
0.1 0.2 GO:0044278 cell wall disruption in other organism(GO:0044278)
0.1 0.3 GO:0099558 maintenance of synapse structure(GO:0099558)
0.1 0.2 GO:0006288 base-excision repair, DNA ligation(GO:0006288)
0.1 0.4 GO:0035995 detection of muscle stretch(GO:0035995)
0.1 0.2 GO:0042335 cuticle development(GO:0042335)
0.1 0.2 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
0.1 0.2 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.1 0.5 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.2 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.0 0.3 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.0 0.1 GO:0070846 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
0.0 0.2 GO:0050915 sensory perception of sour taste(GO:0050915)
0.0 0.1 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.0 0.1 GO:0035565 regulation of pronephros size(GO:0035565)
0.0 0.2 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.0 0.3 GO:0002155 regulation of thyroid hormone mediated signaling pathway(GO:0002155)
0.0 1.0 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.0 0.4 GO:0043416 regulation of skeletal muscle tissue regeneration(GO:0043416)
0.0 0.1 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.0 1.7 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.1 GO:0046271 phenylpropanoid catabolic process(GO:0046271)
0.0 0.1 GO:0098923 retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543)
0.0 0.4 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.0 0.3 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.1 GO:0016240 autophagosome docking(GO:0016240)
0.0 0.2 GO:0009438 methylglyoxal metabolic process(GO:0009438)
0.0 0.2 GO:0072656 maintenance of protein location in mitochondrion(GO:0072656)
0.0 0.2 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.3 GO:0042407 cristae formation(GO:0042407)
0.0 0.4 GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.0 0.1 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
0.0 0.1 GO:0016476 regulation of embryonic cell shape(GO:0016476)
0.0 0.1 GO:0055011 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.0 0.0 GO:0035674 tricarboxylic acid transmembrane transport(GO:0035674)
0.0 0.1 GO:0001714 endodermal cell fate specification(GO:0001714)
0.0 0.1 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902) negative regulation of membrane depolarization(GO:1904180)
0.0 0.0 GO:0071676 negative regulation of mononuclear cell migration(GO:0071676)
0.0 0.1 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.0 0.1 GO:0045007 depurination(GO:0045007)
0.0 0.2 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.0 0.2 GO:0034465 response to carbon monoxide(GO:0034465)
0.0 0.0 GO:0003433 chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
0.0 0.3 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.2 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.1 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.0 0.1 GO:0046836 glycolipid transport(GO:0046836)
0.0 0.2 GO:0014029 neural crest formation(GO:0014029)
0.0 0.2 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:1905103 integral component of lysosomal membrane(GO:1905103)
0.1 0.5 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.0 0.3 GO:0061617 MICOS complex(GO:0061617)
0.0 0.4 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 1.7 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.8 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.2 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.3 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.3 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.1 GO:0020016 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.0 0.3 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.2 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.0 0.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.2 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.0 0.4 GO:0031143 pseudopodium(GO:0031143)
0.0 0.1 GO:0032021 NELF complex(GO:0032021)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.1 0.3 GO:0031531 thyrotropin-releasing hormone receptor binding(GO:0031531)
0.1 0.8 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 0.4 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.1 0.8 GO:0031433 telethonin binding(GO:0031433)
0.0 0.1 GO:0031780 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
0.0 0.6 GO:0030911 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) TPR domain binding(GO:0030911)
0.0 0.2 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.4 GO:0031013 troponin I binding(GO:0031013)
0.0 0.1 GO:0004766 spermidine synthase activity(GO:0004766)
0.0 0.2 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 0.2 GO:0015065 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0 1.7 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.2 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.3 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.0 0.3 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.1 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 0.1 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.0 0.2 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.2 GO:0008865 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.2 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.1 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.2 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 0.1 GO:0046573 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.0 0.0 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.0 0.4 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0 0.1 GO:0042806 fucose binding(GO:0042806)
0.0 0.2 GO:0042834 peptidoglycan binding(GO:0042834) oligosaccharide binding(GO:0070492)
0.0 0.1 GO:0030345 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0 0.2 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.1 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.0 0.2 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.2 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.0 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.3 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.6 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.2 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors