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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for NKX6-2

Z-value: 0.56

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Transcription factors associated with NKX6-2

Gene Symbol Gene ID Gene Info
ENSG00000148826.9 NKX6-2

Activity profile of NKX6-2 motif

Sorted Z-values of NKX6-2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of NKX6-2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr3_-_142028597 1.29 ENST00000467667.5
transcription factor Dp-2
chr2_-_136116165 1.06 ENST00000409817.1
C-X-C motif chemokine receptor 4
chr4_-_89838289 1.03 ENST00000336904.7
synuclein alpha
chr18_-_55587335 1.01 ENST00000638154.3
transcription factor 4
chr9_+_79572715 0.98 ENST00000265284.10
TLE family member 4, transcriptional corepressor
chr9_+_79572572 0.97 ENST00000435650.5
ENST00000414465.5
ENST00000376537.8
TLE family member 4, transcriptional corepressor
chr12_+_32502114 0.87 ENST00000682739.1
ENST00000427716.7
ENST00000583694.2
FYVE, RhoGEF and PH domain containing 4
chr4_-_139280179 0.87 ENST00000398955.2
mitochondria localized glutamic acid rich protein
chr2_+_108378176 0.85 ENST00000409309.3
sulfotransferase family 1C member 4
chr18_+_44680093 0.84 ENST00000426838.8
ENST00000677068.1
SET binding protein 1
chr2_+_108377947 0.83 ENST00000272452.7
sulfotransferase family 1C member 4
chr3_-_142029108 0.83 ENST00000497579.5
transcription factor Dp-2
chr8_+_96584920 0.75 ENST00000521590.5
syndecan 2
chr5_-_111756245 0.68 ENST00000447165.6
neuronal regeneration related protein
chrX_+_136148440 0.67 ENST00000627383.2
ENST00000630084.2
four and a half LIM domains 1
chr14_-_50561119 0.66 ENST00000555216.5
mitogen-activated protein kinase kinase kinase kinase 5
chr3_-_142028617 0.65 ENST00000477292.5
ENST00000478006.5
ENST00000495310.5
ENST00000486111.5
transcription factor Dp-2
chr9_+_79571956 0.58 ENST00000376552.8
TLE family member 4, transcriptional corepressor
chr2_+_172928165 0.57 ENST00000535187.5
Rap guanine nucleotide exchange factor 4
chr18_-_500692 0.51 ENST00000400256.5
collectin subfamily member 12
chr1_+_77918128 0.50 ENST00000342754.5
nexilin F-actin binding protein
chr1_-_109393197 0.50 ENST00000538502.5
ENST00000482236.5
sortilin 1
chr9_+_34652167 0.48 ENST00000441545.7
ENST00000553620.5
interleukin 11 receptor subunit alpha
chr13_-_44474296 0.47 ENST00000611198.4
TSC22 domain family member 1
chr8_-_81483226 0.45 ENST00000256104.5
fatty acid binding protein 4
chr1_-_110391041 0.42 ENST00000369781.8
ENST00000437429.6
ENST00000541986.5
solute carrier family 16 member 4
chr1_-_110390989 0.42 ENST00000369779.9
ENST00000472422.6
solute carrier family 16 member 4
chr2_-_55334529 0.42 ENST00000645860.1
ENST00000642563.1
ENST00000647396.1
coiled-coil domain containing 88A
chrX_+_55717796 0.41 ENST00000262850.7
Ras related GTP binding B
chr22_-_28741783 0.41 ENST00000439200.5
ENST00000405598.5
ENST00000398017.3
ENST00000649563.1
ENST00000650281.1
ENST00000425190.7
ENST00000404276.6
ENST00000650233.1
ENST00000348295.7
ENST00000382580.6
checkpoint kinase 2
chr2_+_190649062 0.39 ENST00000409581.5
ENST00000337386.10
NGFI-A binding protein 1
chr21_-_26090035 0.39 ENST00000448850.5
amyloid beta precursor protein
chr2_+_178284907 0.39 ENST00000409631.5
oxysterol binding protein like 6
chrX_-_81201886 0.38 ENST00000451455.1
ENST00000358130.7
ENST00000436386.5
high mobility group nucleosome binding domain 5
chr18_-_33136075 0.38 ENST00000581852.5
coiled-coil domain containing 178
chr4_-_25863537 0.36 ENST00000502949.5
ENST00000264868.9
ENST00000513691.1
ENST00000514872.1
SEL1L family member 3
chr14_+_63204436 0.35 ENST00000316754.8
ras homolog family member J
chr21_-_30487436 0.35 ENST00000334055.5
keratin associated protein 19-2
chrX_+_55717733 0.35 ENST00000414239.5
ENST00000374941.9
Ras related GTP binding B
chr21_-_30492008 0.35 ENST00000334063.6
keratin associated protein 19-3
chr12_+_110846960 0.34 ENST00000545036.5
ENST00000308208.10
coiled-coil domain containing 63
chr12_+_110847000 0.33 ENST00000552694.1
coiled-coil domain containing 63
chr14_-_75063990 0.33 ENST00000555135.1
ENST00000357971.7
ENST00000553302.1
ENST00000238618.8
ENST00000555694.5
acylphosphatase 1
chr1_-_109613070 0.32 ENST00000351050.8
G protein subunit alpha transducin 2
chr20_-_25390776 0.31 ENST00000376542.8
ENST00000339157.10
abhydrolase domain containing 12, lysophospholipase
chr1_-_175023408 0.31 ENST00000476371.1
mitochondrial ribosomal protein S14
chr6_+_132538290 0.31 ENST00000434551.2
trace amine associated receptor 9
chr1_+_174964750 0.30 ENST00000367688.3
RAB GTPase activating protein 1 like
chr12_+_101594849 0.29 ENST00000547405.5
ENST00000452455.6
ENST00000392934.7
ENST00000547509.5
ENST00000361685.6
ENST00000549145.5
ENST00000361466.7
ENST00000553190.5
ENST00000545503.6
ENST00000536007.5
ENST00000541119.5
ENST00000551300.5
ENST00000550270.1
myosin binding protein C1
chr18_+_75210789 0.27 ENST00000580243.3
teashirt zinc finger homeobox 1
chr18_-_12656716 0.27 ENST00000462226.1
ENST00000497844.6
ENST00000309836.9
ENST00000453447.6
spire type actin nucleation factor 1
chr18_-_55351977 0.27 ENST00000643689.1
transcription factor 4
chr3_-_15798184 0.26 ENST00000624145.3
ankyrin repeat domain 28
chr3_-_98522514 0.26 ENST00000503004.5
ENST00000506575.1
ENST00000513452.5
ENST00000515620.5
claudin domain containing 1
chr18_+_75210755 0.25 ENST00000322038.5
teashirt zinc finger homeobox 1
chr4_-_109801978 0.24 ENST00000510800.1
ENST00000512148.5
ENST00000394634.7
ENST00000394635.8
ENST00000645635.1
complement factor I
novel protein
chr7_+_150368189 0.24 ENST00000519397.1
ENST00000479668.5
replication initiator 1
chr5_+_95731300 0.24 ENST00000379982.8
Rho related BTB domain containing 3
chr17_+_59940908 0.24 ENST00000591035.1
novel protein
chr1_+_100345018 0.23 ENST00000635056.2
ENST00000647005.1
cell division cycle 14A
chr5_-_88823763 0.23 ENST00000635898.1
ENST00000626391.2
ENST00000628656.2
myocyte enhancer factor 2C
chr16_-_67483541 0.22 ENST00000290953.3
agouti related neuropeptide
chr11_-_31509588 0.22 ENST00000534812.5
ENST00000529749.5
ENST00000532287.6
ENST00000278200.5
ENST00000530023.5
ENST00000533642.1
inner mitochondrial membrane peptidase subunit 1
chr2_-_190250503 0.22 ENST00000409820.2
ENST00000410045.5
3-hydroxyisobutyryl-CoA hydrolase
chr7_-_93226449 0.22 ENST00000394468.7
ENST00000453812.2
HEPACAM family member 2
chr2_+_209579399 0.21 ENST00000360351.8
microtubule associated protein 2
chrX_-_10576901 0.21 ENST00000380779.5
midline 1
chr12_+_80099535 0.21 ENST00000646859.1
ENST00000547103.7
otogelin like
chr7_-_138002017 0.21 ENST00000452463.5
ENST00000456390.5
ENST00000330387.11
cAMP responsive element binding protein 3 like 2
chr7_-_22193824 0.21 ENST00000401957.6
Rap guanine nucleotide exchange factor 5
chr1_-_186461089 0.21 ENST00000391997.3
phosducin
chr16_+_25216943 0.21 ENST00000219660.6
aquaporin 8
chr3_+_159839847 0.20 ENST00000445224.6
schwannomin interacting protein 1
chrX_+_10156960 0.20 ENST00000380833.9
chloride voltage-gated channel 4
chr17_-_69060906 0.19 ENST00000495634.5
ENST00000453985.6
ENST00000340001.9
ENST00000585714.1
ATP binding cassette subfamily A member 9
chr15_+_92900338 0.19 ENST00000625990.3
chromodomain helicase DNA binding protein 2
chr22_-_33572227 0.19 ENST00000674780.1
LARGE xylosyl- and glucuronyltransferase 1
chr13_-_48413105 0.18 ENST00000620633.5
lysophosphatidic acid receptor 6
chr5_+_102808057 0.18 ENST00000684043.1
ENST00000682407.1
peptidylglycine alpha-amidating monooxygenase
chr1_+_210328244 0.18 ENST00000541565.5
ENST00000413764.6
hedgehog acyltransferase
chr2_+_209579598 0.18 ENST00000445941.5
ENST00000673860.1
microtubule associated protein 2
chr6_-_130956371 0.17 ENST00000639623.1
ENST00000525193.5
ENST00000527659.5
erythrocyte membrane protein band 4.1 like 2
chr2_+_201183120 0.16 ENST00000272879.9
ENST00000286186.11
ENST00000374650.7
ENST00000346817.9
ENST00000313728.11
ENST00000448480.1
caspase 10
chr1_-_21050952 0.15 ENST00000264211.12
eukaryotic translation initiation factor 4 gamma 3
chr7_+_107583919 0.15 ENST00000491150.5
B cell receptor associated protein 29
chr16_+_31259922 0.14 ENST00000648685.1
ENST00000544665.9
integrin subunit alpha M
chr17_-_59151794 0.14 ENST00000584089.1
spindle and kinetochore associated complex subunit 2
chr2_-_65366650 0.14 ENST00000443619.6
sprouty related EVH1 domain containing 2
chr17_-_59155235 0.14 ENST00000581068.5
spindle and kinetochore associated complex subunit 2
chr6_+_41053194 0.14 ENST00000244669.3
apolipoprotein B mRNA editing enzyme catalytic subunit 2
chr7_+_143959927 0.13 ENST00000624504.1
olfactory receptor family 2 subfamily F member 1
chr1_+_244461270 0.12 ENST00000366534.9
catsper channel auxiliary subunit epsilon
chr1_+_244461386 0.12 ENST00000366533.8
ENST00000428042.1
catsper channel auxiliary subunit epsilon
chr1_+_244461370 0.12 ENST00000366531.7
catsper channel auxiliary subunit epsilon
chr10_-_92497727 0.12 ENST00000496903.5
ENST00000678824.1
ENST00000371581.9
insulin degrading enzyme
chr17_+_75667390 0.11 ENST00000583536.5
SAP30 binding protein
chr19_+_55769118 0.11 ENST00000341750.5
ret finger protein like 4A like 1
chr2_+_11724333 0.11 ENST00000425416.6
ENST00000396097.5
lipin 1
chr18_+_79069385 0.11 ENST00000426216.6
ENST00000307671.12
ENST00000586672.5
ENST00000586722.5
ATPase phospholipid transporting 9B (putative)
chrX_+_34942790 0.11 ENST00000329357.6
family with sequence similarity 47 member B
chr7_-_102642791 0.11 ENST00000340457.8
uroplakin 3B like 1
chr11_-_62754141 0.11 ENST00000527994.1
ENST00000394807.5
ENST00000673933.1
zinc finger and BTB domain containing 3
chr20_-_18497218 0.11 ENST00000337227.9
RB binding protein 9, serine hydrolase
chr11_-_5227063 0.10 ENST00000335295.4
ENST00000485743.1
ENST00000647020.1
hemoglobin subunit beta
chr17_-_59155164 0.10 ENST00000583380.5
ENST00000580541.1
ENST00000578105.1
ENST00000330137.12
ENST00000437036.6
spindle and kinetochore associated complex subunit 2
chr7_-_36985060 0.10 ENST00000396040.6
engulfment and cell motility 1
chr1_-_226739271 0.10 ENST00000429204.6
ENST00000366784.1
inositol-trisphosphate 3-kinase B
chr13_+_53028806 0.10 ENST00000219022.3
olfactomedin 4
chr9_-_21385395 0.09 ENST00000380206.4
interferon alpha 2
chr17_-_44915486 0.09 ENST00000638281.1
ENST00000588316.1
ENST00000588735.3
ENST00000639277.1
ENST00000253408.11
ENST00000435360.8
ENST00000586793.6
ENST00000588037.1
ENST00000592320.6
glial fibrillary acidic protein
chr3_+_16174628 0.09 ENST00000339732.10
polypeptide N-acetylgalactosaminyltransferase 15
chr2_-_206159194 0.09 ENST00000455934.6
ENST00000449699.5
ENST00000454195.1
NADH:ubiquinone oxidoreductase core subunit S1
chr1_-_17439657 0.09 ENST00000375436.9
regulator of chromosome condensation 2
chr2_+_68734861 0.08 ENST00000467265.5
Rho GTPase activating protein 25
chr10_+_88586762 0.08 ENST00000371939.7
lipase family member J
chr13_-_30465224 0.08 ENST00000399494.5
high mobility group box 1
chr17_-_75667088 0.08 ENST00000578201.5
ENST00000423245.6
ENST00000317905.10
RecQ like helicase 5
chr10_-_69409275 0.08 ENST00000373307.5
tachykinin receptor 2
chr2_-_237414157 0.08 ENST00000295550.9
ENST00000353578.9
ENST00000392004.7
ENST00000433762.1
ENST00000392003.6
collagen type VI alpha 3 chain
chr20_+_43507668 0.08 ENST00000434666.5
ENST00000649084.1
ENST00000418998.7
ENST00000427442.8
ENST00000649917.1
L3MBTL histone methyl-lysine binding protein 1
chr6_-_29368865 0.07 ENST00000641768.1
olfactory receptor family 5 subfamily V member 1
chr2_+_206159884 0.07 ENST00000392222.7
eukaryotic translation elongation factor 1 beta 2
chr10_+_70404129 0.07 ENST00000373218.5
eukaryotic translation initiation factor 4E binding protein 2
chr1_-_1390943 0.07 ENST00000408952.8
cyclin L2
chr7_+_101218146 0.07 ENST00000305105.3
zinc finger HIT-type containing 1
chr15_+_78873723 0.07 ENST00000559690.5
ENST00000559158.5
mortality factor 4 like 1
chr3_-_71132099 0.07 ENST00000650188.1
ENST00000648121.1
ENST00000648794.1
ENST00000649592.1
forkhead box P1
chr4_-_151227881 0.07 ENST00000652233.1
ENST00000514152.5
SH3 domain containing 19
chr7_+_77840122 0.07 ENST00000450574.5
ENST00000248550.7
putative homeodomain transcription factor 2
chr4_-_86453075 0.06 ENST00000641384.1
ENST00000642009.1
ENST00000641274.1
ENST00000641629.1
ENST00000641718.1
ENST00000641782.1
ENST00000511328.5
ENST00000503911.5
ENST00000641862.1
ENST00000640445.1
ENST00000641675.1
ENST00000361569.8
ENST00000639989.2
ENST00000641120.1
ENST00000642023.1
ENST00000641902.1
ENST00000641016.1
ENST00000509464.7
ENST00000638946.2
ENST00000395160.9
ENST00000512017.7
ENST00000639972.2
mitogen-activated protein kinase 10
chr11_-_94973541 0.06 ENST00000279839.8
CWC15 spliceosome associated protein homolog
chrX_+_35919725 0.06 ENST00000297866.9
ENST00000378653.8
cilia and flagella associated protein 47
chr6_+_47698538 0.06 ENST00000327753.7
adhesion G protein-coupled receptor F4
chr2_-_216695540 0.06 ENST00000233813.5
insulin like growth factor binding protein 5
chr1_-_158554405 0.06 ENST00000641282.1
ENST00000641622.1
olfactory receptor family 6 subfamily Y member 1
chr6_+_47698574 0.06 ENST00000283303.3
adhesion G protein-coupled receptor F4
chr2_-_206159509 0.06 ENST00000423725.5
NADH:ubiquinone oxidoreductase core subunit S1
chr22_-_29555178 0.05 ENST00000418021.1
THO complex 5
chr17_-_42676980 0.05 ENST00000587627.1
ENST00000591022.6
ENST00000293349.10
pleckstrin homology, MyTH4 and FERM domain containing H3
chrX_-_49043345 0.05 ENST00000315869.8
transcription factor binding to IGHM enhancer 3
chr1_+_86547070 0.05 ENST00000370563.3
chloride channel accessory 4
chrX_-_135764444 0.05 ENST00000597510.6
cancer/testis antigen family 45 member A3
chrX_+_154304923 0.04 ENST00000426989.5
ENST00000426203.5
ENST00000369912.2
transketolase like 1
chr1_-_243163310 0.04 ENST00000492145.1
ENST00000490813.5
ENST00000464936.5
centrosomal protein 170
chr2_-_206159410 0.04 ENST00000457011.5
ENST00000440274.5
ENST00000432169.5
ENST00000233190.11
NADH:ubiquinone oxidoreductase core subunit S1
chr20_-_7940444 0.04 ENST00000378789.4
hydroxyacid oxidase 1
chr16_+_28553908 0.04 ENST00000317058.8
SAGA complex associated factor 29
chr19_-_51082883 0.04 ENST00000650543.2
kallikrein related peptidase 14
chr12_+_53954870 0.04 ENST00000243103.4
homeobox C12
chr1_+_180632001 0.04 ENST00000367590.9
ENST00000367589.3
xenotropic and polytropic retrovirus receptor 1
chr2_+_206159580 0.04 ENST00000236957.9
ENST00000392221.5
ENST00000445505.5
eukaryotic translation elongation factor 1 beta 2
chr5_+_69217798 0.03 ENST00000512880.5
ENST00000602380.1
mitochondrial ribosomal protein S36
chr5_+_69217721 0.03 ENST00000256441.5
mitochondrial ribosomal protein S36
chr11_-_13495984 0.03 ENST00000282091.6
parathyroid hormone
chr7_+_123848070 0.03 ENST00000476325.5
hyaluronidase 4
chr12_-_56741535 0.03 ENST00000647707.1
novel protein
chr6_+_3258914 0.03 ENST00000438998.7
ENST00000419065.6
ENST00000473000.2
ENST00000451246.2
ENST00000454610.2
proteasome assembly chaperone 4
chr15_-_89221558 0.03 ENST00000268125.10
retinaldehyde binding protein 1
chr8_+_75539862 0.02 ENST00000396423.4
hepatocyte nuclear factor 4 gamma
chr16_+_84768246 0.02 ENST00000569925.1
ENST00000567526.1
ubiquitin specific peptidase 10
chr8_+_75539893 0.02 ENST00000674002.1
hepatocyte nuclear factor 4 gamma
chr1_-_145957969 0.02 ENST00000604000.4
limb and CNS expressed 1 like
chr2_-_178108339 0.02 ENST00000358450.8
phosphodiesterase 11A
chr12_-_109021015 0.02 ENST00000546618.2
ENST00000610966.5
SV2 related protein
chr7_-_111392915 0.02 ENST00000450877.5
inner mitochondrial membrane peptidase subunit 2
chr1_-_190477854 0.02 ENST00000367462.5
BMP/retinoic acid inducible neural specific 3
chr4_-_184217854 0.02 ENST00000296741.7
ectonucleotide pyrophosphatase/phosphodiesterase 6
chr1_+_107139996 0.01 ENST00000370073.6
ENST00000370074.8
netrin G1
chr15_+_92900189 0.01 ENST00000626874.2
ENST00000627622.1
ENST00000629346.2
ENST00000628375.2
ENST00000420239.7
ENST00000394196.9
chromodomain helicase DNA binding protein 2
chrX_-_34132311 0.01 ENST00000346193.5
ENST00000613251.1
family with sequence similarity 47 member A
chr10_-_114144599 0.01 ENST00000428953.1
coiled-coil domain containing 186
chr5_-_56116946 0.01 ENST00000434982.2
ankyrin repeat domain 55
chr9_+_107306459 0.01 ENST00000457811.1
RAD23 homolog B, nucleotide excision repair protein
chr9_-_4666347 0.01 ENST00000381890.9
ENST00000682582.1
spermatogenesis associated 6 like
chr5_+_161848112 0.01 ENST00000393943.10
gamma-aminobutyric acid type A receptor subunit alpha1
chr1_+_160400543 0.01 ENST00000368061.3
VANGL planar cell polarity protein 2
chrX_-_135868069 0.01 ENST00000604569.1
cancer/testis antigen family 45 member A9
chr11_-_13496018 0.01 ENST00000529816.1
parathyroid hormone
chr8_-_108787563 0.01 ENST00000297459.4
transmembrane protein 74
chr1_-_150876697 0.00 ENST00000515192.5
aryl hydrocarbon receptor nuclear translocator
chr6_+_3258888 0.00 ENST00000380305.4
proteasome assembly chaperone 4
chr7_+_16661182 0.00 ENST00000446596.5
ENST00000452975.6
ENST00000438834.5
basic leucine zipper and W2 domains 2
chr5_+_161848314 0.00 ENST00000437025.6
gamma-aminobutyric acid type A receptor subunit alpha1
chrX_+_103585478 0.00 ENST00000468024.5
ENST00000415568.2
ENST00000472484.6
ENST00000613326.4
ENST00000490644.5
ENST00000459722.1
ENST00000472745.1
ENST00000494801.5
ENST00000434216.2
transcription elongation factor A like 4
chr11_+_112025968 0.00 ENST00000680411.1
dihydrolipoamide S-acetyltransferase
chr18_-_36798482 0.00 ENST00000590258.2
tubulin polyglutamylase complex subunit 2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0097211 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.2 1.0 GO:1903285 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.1 0.4 GO:1903925 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.1 0.8 GO:0008218 bioluminescence(GO:0008218)
0.1 1.1 GO:0019064 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.1 0.5 GO:0060023 soft palate development(GO:0060023)
0.1 0.8 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.1 0.3 GO:0052651 monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.1 0.4 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.1 1.7 GO:0006068 ethanol catabolic process(GO:0006068)
0.1 0.4 GO:0048669 microglia differentiation(GO:0014004) microglia development(GO:0014005) collateral sprouting in absence of injury(GO:0048669) smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563) cellular response to norepinephrine stimulus(GO:0071874)
0.1 2.8 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1 0.5 GO:0060355 positive regulation of cell adhesion molecule production(GO:0060355)
0.1 0.5 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.2 GO:0018032 protein amidation(GO:0018032)
0.0 0.2 GO:0046116 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.0 0.2 GO:0006574 valine catabolic process(GO:0006574)
0.0 0.7 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 2.5 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 0.3 GO:0070649 formin-nucleated actin cable assembly(GO:0070649)
0.0 0.1 GO:1901143 insulin catabolic process(GO:1901143)
0.0 0.2 GO:0003138 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.0 0.3 GO:0046549 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.5 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.1 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.2 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.5 GO:0071285 cellular response to lithium ion(GO:0071285)
0.0 0.4 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.1 GO:0032696 negative regulation of interleukin-13 production(GO:0032696)
0.0 0.1 GO:0032072 plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072)
0.0 0.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.7 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.2 GO:0008343 adult feeding behavior(GO:0008343)
0.0 0.1 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.1 GO:0035106 operant conditioning(GO:0035106)
0.0 0.1 GO:0033029 regulation of neutrophil apoptotic process(GO:0033029)
0.0 0.1 GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
0.0 0.4 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.0 0.2 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.2 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.0 0.2 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.2 GO:0019321 pentose metabolic process(GO:0019321)
0.0 0.1 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.0 0.2 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.0 GO:0034310 primary alcohol catabolic process(GO:0034310)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 0.2 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.4 GO:1990761 growth cone lamellipodium(GO:1990761)
0.0 0.2 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.0 0.4 GO:0036128 CatSper complex(GO:0036128)
0.0 0.3 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 1.0 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.4 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.7 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.2 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.2 GO:0060091 kinocilium(GO:0060091)
0.0 0.1 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.0 0.3 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 2.7 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.5 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.4 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.1 1.1 GO:0032027 myosin light chain binding(GO:0032027)
0.1 1.7 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.1 0.5 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.1 0.2 GO:0003860 3-hydroxyisobutyryl-CoA hydrolase activity(GO:0003860)
0.1 0.5 GO:0005534 galactose binding(GO:0005534)
0.1 1.3 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 0.3 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.2 GO:0004598 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.0 0.3 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.1 GO:0031626 beta-endorphin binding(GO:0031626)
0.0 0.4 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.2 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.7 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.2 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.1 GO:0016497 substance K receptor activity(GO:0016497)
0.0 0.1 GO:0032093 SAM domain binding(GO:0032093)
0.0 0.3 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.2 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 2.6 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.4 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.1 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.2 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.2 GO:0042731 PH domain binding(GO:0042731)
0.0 0.3 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.2 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.1 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.0 GO:0052854 (S)-2-hydroxy-acid oxidase activity(GO:0003973) very-long-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052852) long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity(GO:0052853) medium-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052854)
0.0 0.3 GO:0031432 titin binding(GO:0031432)
0.0 0.8 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.2 GO:0015250 water channel activity(GO:0015250)
0.0 0.1 GO:0001851 complement component C3b binding(GO:0001851)
0.0 0.1 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.4 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 2.8 PID E2F PATHWAY E2F transcription factor network
0.0 1.0 PID S1P S1P3 PATHWAY S1P3 pathway
0.0 0.9 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.8 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.1 1.7 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 1.4 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 2.5 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.4 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 1.5 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.8 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.5 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.6 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins