ISMARA results: NKX6-3

Project

Inflammatory response time course, HUVEC (Wada, 2009)

Navigation

Downloads

Results for NKX6-3

Z-value: 0.18

Motif logo

Transcription factors associated with NKX6-3

Gene Symbol	Gene ID	Gene Info
NKX6-3 Ensembl NCBI GeneCards UniProt	ENSG00000165066.13	NKX6-3

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
NKX6-3	hg38_v1_chr8_-_41650808_41650822	-0.18	3.8e-01	Click!

Activity profile of NKX6-3 motif

Sorted Z-values of NKX6-3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of NKX6-3

View svg image
View png image

Top targets:

Promoter	Score	Transcript	Gene	Gene Info
chr3_-_191282383 Show fit	0.18	ENST00000427544.6	UTS2B Ensembl NCBI GeneCards UniProt Show fit	urotensin 2B
chr4_-_122621011 Show fit	0.15	ENST00000611104.2 ENST00000648588.1	IL21 Ensembl NCBI GeneCards UniProt Show fit	interleukin 21
chr9_+_122370523 Show fit	0.14	ENST00000643810.1 ENST00000540753.6	PTGS1 Ensembl NCBI GeneCards UniProt Show fit	prostaglandin-endoperoxide synthase 1
chr3_-_142029108 Show fit	0.13	ENST00000497579.5	TFDP2 Ensembl NCBI GeneCards UniProt Show fit	transcription factor Dp-2
chr5_-_58999885 Show fit	0.13	ENST00000317118.12	PDE4D Ensembl NCBI GeneCards UniProt Show fit	phosphodiesterase 4D
chr5_-_140346596 Show fit	0.09	ENST00000230990.7	HBEGF Ensembl NCBI GeneCards UniProt Show fit	heparin binding EGF like growth factor
chr20_-_31390483 Show fit	0.09	ENST00000376315.2	DEFB119 Ensembl NCBI GeneCards UniProt Show fit	defensin beta 119
chr3_-_132684685 Show fit	0.08	ENST00000512094.5 ENST00000632629.1	NPHP3 Ensembl NCBI GeneCards UniProt Show fit NPHP3-ACAD11 Ensembl NCBI GeneCards UniProt Show fit	nephrocystin 3 NPHP3-ACAD11 readthrough (NMD candidate)
chr4_+_75556048 Show fit	0.08	ENST00000616557.1 ENST00000435974.2 ENST00000311623.9	ODAPH Ensembl NCBI GeneCards UniProt Show fit	odontogenesis associated phosphoprotein
chr7_+_130344810 Show fit	0.07	ENST00000497503.5 ENST00000463587.5 ENST00000461828.5 ENST00000474905.6 ENST00000494311.1 ENST00000466363.6	CPA5 Ensembl NCBI GeneCards UniProt Show fit	carboxypeptidase A5
chr14_+_88385643 Show fit	0.07	ENST00000393545.9 ENST00000356583.9 ENST00000555401.5 ENST00000553885.5	SPATA7 Ensembl NCBI GeneCards UniProt Show fit	spermatogenesis associated 7
chr19_-_3557563 Show fit	0.06	ENST00000389395.7 ENST00000355415.7	MFSD12 Ensembl NCBI GeneCards UniProt Show fit	major facilitator superfamily domain containing 12
chr14_+_88385714 Show fit	0.06	ENST00000045347.11	SPATA7 Ensembl NCBI GeneCards UniProt Show fit	spermatogenesis associated 7
chr9_+_122371036 Show fit	0.06	ENST00000619306.5 ENST00000426608.6 ENST00000223423.8	PTGS1 Ensembl NCBI GeneCards UniProt Show fit	prostaglandin-endoperoxide synthase 1
chr19_-_14979848 Show fit	0.06	ENST00000594383.2	SLC1A6 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 1 member 6
chr1_+_160400543 Show fit	0.06	ENST00000368061.3	VANGL2 Ensembl NCBI GeneCards UniProt Show fit	VANGL planar cell polarity protein 2
chr3_+_138621225 Show fit	0.05	ENST00000479848.1	FAIM Ensembl NCBI GeneCards UniProt Show fit	Fas apoptotic inhibitory molecule
chr9_+_121567057 Show fit	0.05	ENST00000394340.7 ENST00000436835.5 ENST00000259371.6	DAB2IP Ensembl NCBI GeneCards UniProt Show fit	DAB2 interacting protein
chr18_+_58341038 Show fit	0.04	ENST00000679791.1	NEDD4L Ensembl NCBI GeneCards UniProt Show fit	NEDD4 like E3 ubiquitin protein ligase
chr17_+_7407838 Show fit	0.04	ENST00000302926.7	NLGN2 Ensembl NCBI GeneCards UniProt Show fit	neuroligin 2
chr6_+_113857333 Show fit	0.04	ENST00000612661.2	MARCKS Ensembl NCBI GeneCards UniProt Show fit	myristoylated alanine rich protein kinase C substrate
chr7_+_138460238 Show fit	0.04	ENST00000343526.9	TRIM24 Ensembl NCBI GeneCards UniProt Show fit	tripartite motif containing 24
chr17_-_10469558 Show fit	0.03	ENST00000255381.2	MYH4 Ensembl NCBI GeneCards UniProt Show fit	myosin heavy chain 4
chr5_+_141150012 Show fit	0.03	ENST00000231136.4 ENST00000622991.1	PCDHB6 Ensembl NCBI GeneCards UniProt Show fit	protocadherin beta 6
chr2_-_99255107 Show fit	0.03	ENST00000333017.6 ENST00000626374.2 ENST00000409679.5 ENST00000423306.1	LYG2 Ensembl NCBI GeneCards UniProt Show fit	lysozyme g2
chr9_+_122371014 Show fit	0.03	ENST00000362012.7	PTGS1 Ensembl NCBI GeneCards UniProt Show fit	prostaglandin-endoperoxide synthase 1
chr18_+_34978244 Show fit	0.03	ENST00000436190.6	MAPRE2 Ensembl NCBI GeneCards UniProt Show fit	microtubule associated protein RP/EB family member 2
chr11_-_13496018 Show fit	0.03	ENST00000529816.1	PTH Ensembl NCBI GeneCards UniProt Show fit	parathyroid hormone
chr19_+_4402615 Show fit	0.02	ENST00000301280.10	CHAF1A Ensembl NCBI GeneCards UniProt Show fit	chromatin assembly factor 1 subunit A
chr12_-_52367478 Show fit	0.02	ENST00000257901.7	KRT85 Ensembl NCBI GeneCards UniProt Show fit	keratin 85
chr17_-_66229380 Show fit	0.02	ENST00000205948.11	APOH Ensembl NCBI GeneCards UniProt Show fit	apolipoprotein H
chrX_+_43656289 Show fit	0.02	ENST00000338702.4	MAOA Ensembl NCBI GeneCards UniProt Show fit	monoamine oxidase A
chr1_-_113871665 Show fit	0.02	ENST00000528414.5 ENST00000460620.5 ENST00000359785.10 ENST00000420377.6 ENST00000525799.1 ENST00000538253.5	PTPN22 Ensembl NCBI GeneCards UniProt Show fit	protein tyrosine phosphatase non-receptor type 22
chr16_-_67483541 Show fit	0.02	ENST00000290953.3	AGRP Ensembl NCBI GeneCards UniProt Show fit	agouti related neuropeptide
chr16_+_86566821 Show fit	0.02	ENST00000649859.1	FOXC2 Ensembl NCBI GeneCards UniProt Show fit	forkhead box C2
chr3_-_165078480 Show fit	0.01	ENST00000264382.8	SI Ensembl NCBI GeneCards UniProt Show fit	sucrase-isomaltase
chr15_+_48191648 Show fit	0.01	ENST00000646012.1 ENST00000561127.5 ENST00000647546.1 ENST00000559641.5 ENST00000417307.3	SLC12A1 Ensembl NCBI GeneCards UniProt Show fit CTXN2 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 12 member 1 cortexin 2
chr20_-_7940444 Show fit	0.01	ENST00000378789.4	HAO1 Ensembl NCBI GeneCards UniProt Show fit	hydroxyacid oxidase 1
chr6_+_130018565 Show fit	0.01	ENST00000361794.7 ENST00000526087.5 ENST00000533560.5	L3MBTL3 Ensembl NCBI GeneCards UniProt Show fit	L3MBTL histone methyl-lysine binding protein 3
chr1_-_151459471 Show fit	0.01	ENST00000271715.7	POGZ Ensembl NCBI GeneCards UniProt Show fit	pogo transposable element derived with ZNF domain
chrX_+_47836877 Show fit	0.01	ENST00000338637.13 ENST00000376954.6	ZNF81 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 81
chr8_+_91249307 Show fit	0.01	ENST00000309536.6 ENST00000276609.8	SLC26A7 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 26 member 7
chr11_-_13495984 Show fit	0.01	ENST00000282091.6	PTH Ensembl NCBI GeneCards UniProt Show fit	parathyroid hormone
chr5_-_143400716 Show fit	0.01	ENST00000424646.6 ENST00000652686.1	NR3C1 Ensembl NCBI GeneCards UniProt Show fit	nuclear receptor subfamily 3 group C member 1
chr13_+_53028806 Show fit	0.01	ENST00000219022.3	OLFM4 Ensembl NCBI GeneCards UniProt Show fit	olfactomedin 4
chr8_+_76681208 Show fit	0.01	ENST00000651372.2	ZFHX4 Ensembl NCBI GeneCards UniProt Show fit	zinc finger homeobox 4
chr10_+_18260715 Show fit	0.01	ENST00000615785.4 ENST00000617363.4 ENST00000396576.6	CACNB2 Ensembl NCBI GeneCards UniProt Show fit	calcium voltage-gated channel auxiliary subunit beta 2
chr3_+_138621207 Show fit	0.00	ENST00000464668.5	FAIM Ensembl NCBI GeneCards UniProt Show fit	Fas apoptotic inhibitory molecule
chr1_-_151459169 Show fit	0.00	ENST00000368863.6 ENST00000409503.5 ENST00000491586.5 ENST00000533351.5	POGZ Ensembl NCBI GeneCards UniProt Show fit	pogo transposable element derived with ZNF domain

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Total log-likelihood	Term	Description
0.1	GO:0061346	non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
0.1	GO:0048496	maintenance of organ identity(GO:0048496)
0.0	GO:1904862	inhibitory synapse assembly(GO:1904862)
0.1	GO:0086024	adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1	GO:1903546	protein localization to photoreceptor outer segment(GO:1903546)
0.1	GO:0051541	elastin metabolic process(GO:0051541)
0.2	GO:0019371	cyclooxygenase pathway(GO:0019371)

Gene overrepresentation in cellular component category:

Total log-likelihood	Term	Description
0.1	GO:0097543	ciliary inversin compartment(GO:0097543)
0.1	GO:0060187	cell pole(GO:0060187)
0.0	GO:0001674	female germ cell nucleus(GO:0001674)
0.0	GO:1990032	parallel fiber(GO:1990032)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.2	GO:0004666	prostaglandin-endoperoxide synthase activity(GO:0004666)
0.0	0.1	GO:0005134	interleukin-2 receptor binding(GO:0005134)

Results for NKX6-3

Z-value: 0.18

Motif logo

Transcription factors associated with NKX6-3

Activity-expression correlation:

Activity profile of NKX6-3 motif

Sorted Z-values of NKX6-3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of NKX6-3

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.

Top targets:

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category: