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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for NR0B1

Z-value: 0.53

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Transcription factors associated with NR0B1

Gene Symbol Gene ID Gene Info
ENSG00000169297.8 NR0B1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR0B1hg38_v1_chrX_-_30308333_30308488-0.135.4e-01Click!

Activity profile of NR0B1 motif

Sorted Z-values of NR0B1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of NR0B1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr2_-_225042433 1.83 ENST00000258390.12
dedicator of cytokinesis 10
chr7_-_108456378 1.00 ENST00000613830.4
ENST00000413765.6
ENST00000379028.8
neuronal cell adhesion molecule
chr9_+_70043840 0.88 ENST00000377182.5
MAM domain containing 2
chr7_-_108456321 0.85 ENST00000379024.8
ENST00000351718.8
neuronal cell adhesion molecule
chr4_-_176792913 0.82 ENST00000618562.2
vascular endothelial growth factor C
chr17_+_79024243 0.67 ENST00000311661.4
C1q and TNF related 1
chr8_-_141000937 0.64 ENST00000520892.5
protein tyrosine kinase 2
chr13_-_33285682 0.53 ENST00000336934.10
StAR related lipid transfer domain containing 13
chr5_+_68215738 0.52 ENST00000521381.6
ENST00000521657.5
phosphoinositide-3-kinase regulatory subunit 1
chr20_-_37178966 0.47 ENST00000422138.1
maestro heat like repeat family member 8
chr2_+_30231524 0.45 ENST00000395323.9
ENST00000406087.5
ENST00000404397.5
LBH regulator of WNT signaling pathway
chr4_-_2756288 0.43 ENST00000510267.5
ENST00000315423.12
ENST00000503235.1
TNFAIP3 interacting protein 2
chr1_-_223364059 0.43 ENST00000343846.7
ENST00000484758.6
ENST00000344029.6
ENST00000366878.9
ENST00000494793.6
ENST00000681285.1
ENST00000680429.1
ENST00000681669.1
ENST00000681305.1
sushi domain containing 4
chr20_-_18057841 0.42 ENST00000278780.7
ovo like zinc finger 2
chr12_-_27780236 0.41 ENST00000381273.4
MANSC domain containing 4
chr10_-_13707536 0.38 ENST00000632570.1
ENST00000477221.2
FERM domain containing 4A
chr6_-_29633171 0.38 ENST00000377034.9
gamma-aminobutyric acid type B receptor subunit 1
chr16_+_1153202 0.37 ENST00000358590.8
ENST00000638323.1
calcium voltage-gated channel subunit alpha1 H
chr6_-_29633056 0.37 ENST00000377016.8
gamma-aminobutyric acid type B receptor subunit 1
chr1_+_18107763 0.36 ENST00000251296.4
immunoglobin superfamily member 21
chr4_-_119628007 0.36 ENST00000420633.1
ENST00000394439.5
phosphodiesterase 5A
chr2_+_85753984 0.35 ENST00000306279.4
atonal bHLH transcription factor 8
chr16_-_11586903 0.33 ENST00000571459.5
ENST00000570798.5
ENST00000622633.5
ENST00000572255.5
ENST00000574763.5
ENST00000574703.5
ENST00000571277.1
lipopolysaccharide induced TNF factor
chr19_+_41845018 0.33 ENST00000596827.5
DMRT like family C2
chr3_-_122993232 0.33 ENST00000650207.1
ENST00000616742.4
ENST00000393583.6
semaphorin 5B
chr12_+_56080126 0.32 ENST00000411731.6
erb-b2 receptor tyrosine kinase 3
chr2_-_152099023 0.32 ENST00000201943.10
ENST00000427385.6
ENST00000539935.7
calcium voltage-gated channel auxiliary subunit beta 4
chr14_-_91253925 0.32 ENST00000531499.2
G protein-coupled receptor 68
chr12_+_54561442 0.32 ENST00000550620.1
phosphodiesterase 1B
chrX_-_69165430 0.32 ENST00000374584.3
ENST00000590146.1
ENST00000374571.5
praja ring finger ubiquitin ligase 1
chr2_-_152099155 0.32 ENST00000637309.1
calcium voltage-gated channel auxiliary subunit beta 4
chrX_-_69165509 0.31 ENST00000361478.1
praja ring finger ubiquitin ligase 1
chr1_+_11664191 0.30 ENST00000376753.9
F-box protein 6
chr2_+_219627650 0.29 ENST00000317151.7
solute carrier family 4 member 3
chr6_+_7541612 0.29 ENST00000418664.2
desmoplakin
chr1_-_154627576 0.29 ENST00000648311.1
adenosine deaminase RNA specific
chr1_-_154627945 0.29 ENST00000681683.1
ENST00000368471.8
ENST00000649042.1
ENST00000680270.1
ENST00000649022.2
ENST00000681056.1
ENST00000649724.1
adenosine deaminase RNA specific
chr1_-_40665435 0.29 ENST00000372683.1
regulating synaptic membrane exocytosis 3
chr13_-_37869723 0.28 ENST00000426868.6
ENST00000379705.8
ENST00000338947.9
ENST00000355779.6
ENST00000358477.6
ENST00000379673.2
transient receptor potential cation channel subfamily C member 4
chr6_+_7541662 0.28 ENST00000379802.8
desmoplakin
chr17_-_7393404 0.28 ENST00000575434.4
phospholipid scramblase 3
chr17_-_7252054 0.28 ENST00000575783.5
ENST00000573600.5
CTD nuclear envelope phosphatase 1
chr2_+_184598520 0.27 ENST00000302277.7
zinc finger protein 804A
chr9_-_130939205 0.27 ENST00000372338.9
fibrinogen C domain containing 1
chr20_-_4015518 0.26 ENST00000545616.2
ENST00000358395.11
ring finger protein 24
chr1_-_223363337 0.26 ENST00000608996.5
sushi domain containing 4
chr16_-_67247460 0.25 ENST00000258201.9
formin homology 2 domain containing 1
chr17_-_1486124 0.25 ENST00000575158.5
myosin IC
chr2_+_219627565 0.24 ENST00000273063.10
solute carrier family 4 member 3
chr1_-_196608359 0.24 ENST00000609185.5
ENST00000451324.6
ENST00000367433.9
ENST00000294725.14
potassium sodium-activated channel subfamily T member 2
chr19_-_40348510 0.24 ENST00000582006.5
ENST00000582783.5
chromosome 19 open reading frame 47
chr2_+_219627622 0.23 ENST00000358055.8
solute carrier family 4 member 3
chr19_+_41845029 0.23 ENST00000269945.8
ENST00000596258.5
DMRT like family C2
chrX_+_9465011 0.23 ENST00000645353.2
transducin beta like 1 X-linked
chr6_+_31158518 0.23 ENST00000376255.4
ENST00000376257.8
transcription factor 19
chr17_-_7251955 0.23 ENST00000318988.10
CTD nuclear envelope phosphatase 1
chr19_+_1205761 0.22 ENST00000326873.12
ENST00000586243.5
serine/threonine kinase 11
chr12_+_106774630 0.22 ENST00000392839.6
ENST00000548914.5
ENST00000355478.6
ENST00000552619.1
ENST00000549643.5
ENST00000392837.9
RIC8 guanine nucleotide exchange factor B
chr12_-_116276759 0.22 ENST00000548743.2
mediator complex subunit 13L
chr20_-_4015389 0.22 ENST00000336095.10
ring finger protein 24
chr1_-_183635776 0.22 ENST00000359856.11
actin related protein 2/3 complex subunit 5
chr1_+_2556361 0.22 ENST00000355716.5
TNF receptor superfamily member 14
chr16_+_1153098 0.22 ENST00000348261.11
calcium voltage-gated channel subunit alpha1 H
chr10_+_69451456 0.22 ENST00000373290.7
tetraspanin 15
chr1_-_34929574 0.21 ENST00000373347.6
DLG associated protein 3
chr19_-_40348375 0.21 ENST00000392035.6
ENST00000683109.1
chromosome 19 open reading frame 47
chr2_+_26034069 0.21 ENST00000264710.5
RAB10, member RAS oncogene family
chr19_-_14979848 0.21 ENST00000594383.2
solute carrier family 1 member 6
chr11_+_64035925 0.21 ENST00000682287.1
fibronectin leucine rich transmembrane protein 1
chr1_+_15617415 0.20 ENST00000480945.6
DNA damage inducible 1 homolog 2
chr10_-_17454582 0.20 ENST00000377602.5
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6
chr12_-_1594568 0.20 ENST00000339235.4
F-box and leucine rich repeat protein 14
chr7_+_149715003 0.20 ENST00000496259.5
ENST00000319551.12
KRAB-A domain containing 1
chr12_-_132761814 0.20 ENST00000357997.10
ankyrin repeat and LEM domain containing 2
chr20_+_58891704 0.20 ENST00000371081.5
ENST00000338783.7
GNAS complex locus
chr1_+_31413806 0.20 ENST00000536384.2
serine incorporator 2
chr2_+_219627394 0.19 ENST00000373760.6
solute carrier family 4 member 3
chr1_-_147773341 0.19 ENST00000430508.1
ENST00000621517.1
gap junction protein alpha 5
chr11_-_111912871 0.19 ENST00000528628.5
crystallin alpha B
chr2_-_175005357 0.19 ENST00000409156.7
ENST00000444573.2
ENST00000409900.9
chimerin 1
chr17_+_31094969 0.19 ENST00000431387.8
ENST00000358273.9
neurofibromin 1
chr22_-_49824804 0.19 ENST00000216267.12
ENST00000457780.3
bromodomain containing 1
chr1_-_197201262 0.19 ENST00000367405.5
zinc finger and BTB domain containing 41
chr7_-_151632330 0.19 ENST00000418337.6
protein kinase AMP-activated non-catalytic subunit gamma 2
chr22_-_41589794 0.19 ENST00000216259.8
phosphomannomutase 1
chr3_+_152835122 0.19 ENST00000305097.6
purinergic receptor P2Y1
chr17_+_48107743 0.18 ENST00000359238.7
ENST00000582104.5
ENST00000584335.5
sorting nexin 11
chr19_-_38229654 0.18 ENST00000412732.5
ENST00000456296.5
double PHD fingers 1
chr17_+_48107549 0.18 ENST00000580219.5
ENST00000452859.6
ENST00000393405.6
sorting nexin 11
chr8_-_141001217 0.18 ENST00000522684.5
ENST00000524357.5
ENST00000521332.5
ENST00000524040.5
ENST00000519881.5
ENST00000520045.5
protein tyrosine kinase 2
chr22_+_17369420 0.18 ENST00000262608.13
ENST00000342247.10
CECR2 histone acetyl-lysine reader
chr16_-_3443446 0.18 ENST00000301744.7
zinc finger protein 597
chr2_-_173964180 0.18 ENST00000418194.7
Sp3 transcription factor
chr17_+_31094880 0.17 ENST00000487476.5
ENST00000356175.7
neurofibromin 1
chr6_-_100464912 0.17 ENST00000369208.8
SIM bHLH transcription factor 1
chr22_-_31140494 0.17 ENST00000215885.4
phospholipase A2 group III
chr8_+_26291758 0.17 ENST00000522535.5
ENST00000665949.1
protein phosphatase 2 regulatory subunit Balpha
chr21_+_42653734 0.17 ENST00000335512.8
ENST00000328862.10
ENST00000335440.10
ENST00000380328.6
ENST00000398225.7
ENST00000398227.7
ENST00000398229.7
ENST00000398232.7
ENST00000398234.7
ENST00000398236.7
ENST00000349112.7
ENST00000398224.3
phosphodiesterase 9A
chr19_+_35351552 0.17 ENST00000246553.3
free fatty acid receptor 1
chr15_+_74130551 0.17 ENST00000453268.3
immunoglobulin superfamily containing leucine rich repeat 2
chr20_+_44885679 0.17 ENST00000353703.9
ENST00000372839.7
ENST00000428262.1
ENST00000445830.1
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta
chrX_+_148500883 0.17 ENST00000370458.5
ENST00000370457.9
AF4/FMR2 family member 2
chr17_-_55421818 0.16 ENST00000262065.8
ENST00000649377.1
monocyte to macrophage differentiation associated
chr20_+_45833843 0.16 ENST00000342644.9
ENST00000372542.5
sorting nexin family member 21
chr3_-_182980531 0.16 ENST00000292782.9
ENST00000632685.1
defective in cullin neddylation 1 domain containing 1
chr15_-_50765656 0.16 ENST00000261854.10
signal peptide peptidase like 2A
chr11_+_117232625 0.16 ENST00000534428.5
ENST00000300650.9
ring finger protein 214
chr19_-_38229714 0.16 ENST00000416611.5
double PHD fingers 1
chr1_+_113905290 0.16 ENST00000650450.2
DNA cross-link repair 1B
chr16_-_70680025 0.16 ENST00000576338.1
MTSS I-BAR domain containing 2
chr3_-_11582330 0.16 ENST00000451674.6
vestigial like family member 4
chr16_+_19168207 0.16 ENST00000355377.7
ENST00000568115.5
synaptotagmin 17
chr1_-_40665654 0.16 ENST00000372684.8
regulating synaptic membrane exocytosis 3
chr3_-_100401028 0.16 ENST00000284320.6
translocase of outer mitochondrial membrane 70
chr1_+_155277414 0.15 ENST00000368358.4
hyperpolarization activated cyclic nucleotide gated potassium channel 3
chr17_-_65560296 0.15 ENST00000585045.1
ENST00000611991.1
axin 2
chr17_-_39197652 0.15 ENST00000394303.8
calcium voltage-gated channel auxiliary subunit beta 1
chr9_-_128204218 0.15 ENST00000634901.1
ENST00000372948.7
CDKN1A interacting zinc finger protein 1
chrX_-_130268883 0.15 ENST00000447817.1
ENST00000370978.9
zinc finger protein 280C
chr10_+_122112957 0.15 ENST00000369001.5
transforming acidic coiled-coil containing protein 2
chr16_-_48610150 0.15 ENST00000262384.4
NEDD4 binding protein 1
chr2_+_48314637 0.15 ENST00000413569.5
ENST00000340553.8
forkhead box N2
chr5_+_139274093 0.15 ENST00000448190.6
ENST00000648842.1
ENST00000507692.5
ENST00000506188.5
ENST00000513259.5
ENST00000507197.5
ENST00000508735.5
ENST00000514110.5
ENST00000505522.6
ENST00000361059.7
ENST00000514694.5
ENST00000504203.5
ENST00000502929.5
ENST00000394800.6
ENST00000509644.5
ENST00000505016.2
small nucleolar RNA host gene 4
matrin 3
chr9_+_37800761 0.14 ENST00000377724.8
DDB1 and CUL4 associated factor 10
chr19_+_55600277 0.14 ENST00000301073.4
zinc finger protein 524
chr19_+_55339867 0.14 ENST00000255613.8
lysine methyltransferase 5C
chr7_+_101020073 0.14 ENST00000306151.9
mucin 17, cell surface associated
chr15_+_74130243 0.14 ENST00000561740.5
ENST00000435464.5
immunoglobulin superfamily containing leucine rich repeat 2
chr15_+_40844018 0.14 ENST00000344051.8
ENST00000562057.6
serine peptidase inhibitor, Kunitz type 1
chr15_+_90872162 0.14 ENST00000680053.1
furin, paired basic amino acid cleaving enzyme
chr2_-_152098810 0.14 ENST00000636442.1
ENST00000638005.1
calcium voltage-gated channel auxiliary subunit beta 4
chr5_-_58999885 0.14 ENST00000317118.12
phosphodiesterase 4D
chr14_+_73490926 0.14 ENST00000304061.8
ribosomal oxygenase 1
chr3_+_72996786 0.14 ENST00000356692.10
ENST00000488810.5
protein phosphatase 4 regulatory subunit 2
chr16_-_788329 0.14 ENST00000563560.1
ENST00000569601.5
ENST00000565809.5
ENST00000007264.7
ENST00000565377.1
ENST00000567114.5
RNA pseudouridine synthase domain containing 1
chr1_-_121183911 0.14 ENST00000355228.8
family with sequence similarity 72 member B
chr1_+_11691688 0.14 ENST00000294485.6
dorsal inhibitory axon guidance protein
chr11_+_35662739 0.13 ENST00000299413.7
tripartite motif containing 44
chr2_+_231708511 0.13 ENST00000341369.11
ENST00000409115.8
ENST00000409683.5
prothymosin alpha
chr17_-_79797030 0.13 ENST00000269385.9
chromobox 8
chr17_-_44123590 0.13 ENST00000336057.9
histone deacetylase 5
chr4_-_108168950 0.13 ENST00000379951.6
lymphoid enhancer binding factor 1
chr3_-_127590707 0.13 ENST00000296210.11
ENST00000355552.8
transmembrane protein adipocyte associated 1
chr8_-_143568854 0.13 ENST00000524906.5
ENST00000532862.1
ENST00000534459.5
maestro heat like repeat family member 6
chr19_+_8364146 0.13 ENST00000301455.7
ENST00000393962.6
angiopoietin like 4
chr20_+_36306325 0.13 ENST00000373913.7
ENST00000339266.10
DLG associated protein 4
chr12_-_6375556 0.13 ENST00000228916.7
sodium channel epithelial 1 subunit alpha
chr11_+_117232725 0.12 ENST00000531287.5
ENST00000531452.5
ring finger protein 214
chr2_-_157628852 0.12 ENST00000243349.13
activin A receptor type 1C
chr2_+_218399838 0.12 ENST00000273062.7
CTD small phosphatase 1
chr15_+_33310946 0.12 ENST00000415757.7
ENST00000634891.2
ENST00000389232.9
ENST00000622037.1
ryanodine receptor 3
chr10_+_96832252 0.12 ENST00000676187.1
ENST00000675687.1
ENST00000676123.1
ENST00000675471.1
ENST00000371103.8
ENST00000421806.4
ENST00000675250.1
ENST00000540664.6
ENST00000676414.1
ligand dependent nuclear receptor corepressor
chr3_+_178536407 0.12 ENST00000452583.6
potassium calcium-activated channel subfamily M regulatory beta subunit 2
chr15_+_57592003 0.12 ENST00000587652.5
ENST00000649429.1
ENST00000380568.7
ENST00000380565.8
GRINL1A complex locus 1
myocardial zonula adherens protein
chr4_-_119627631 0.12 ENST00000264805.9
phosphodiesterase 5A
chr2_-_43995999 0.12 ENST00000683213.1
ENST00000409946.6
leucine rich pentatricopeptide repeat containing
chr3_-_48685835 0.12 ENST00000439518.5
ENST00000416649.6
ENST00000294129.7
NCK interacting protein with SH3 domain
chr10_+_84194621 0.12 ENST00000332904.7
cadherin related family member 1
chr8_+_22275309 0.12 ENST00000356766.11
ENST00000521356.5
piwi like RNA-mediated gene silencing 2
chr17_-_7929793 0.12 ENST00000303790.3
potassium voltage-gated channel subfamily A regulatory beta subunit 3
chr3_-_184261547 0.11 ENST00000296238.4
calcium/calmodulin dependent protein kinase II inhibitor 2
chr20_+_56629296 0.11 ENST00000201031.3
transcription factor AP-2 gamma
chr4_-_108168919 0.11 ENST00000265165.6
lymphoid enhancer binding factor 1
chr12_+_27780224 0.11 ENST00000381271.7
kelch like family member 42
chr20_+_47501929 0.11 ENST00000371997.3
nuclear receptor coactivator 3
chr16_-_68236069 0.11 ENST00000473183.7
ENST00000565858.5
epithelial splicing regulatory protein 2
chr2_-_43995950 0.11 ENST00000683590.1
ENST00000683623.1
ENST00000682779.1
ENST00000682546.1
ENST00000683220.1
ENST00000683125.1
ENST00000683833.1
ENST00000683989.1
ENST00000682480.1
ENST00000260665.12
ENST00000682308.1
ENST00000682885.1
ENST00000409659.6
ENST00000447246.2
leucine rich pentatricopeptide repeat containing
chr3_-_116445458 0.11 ENST00000490035.7
limbic system associated membrane protein
chr19_-_50568426 0.11 ENST00000652263.1
leucine rich repeat containing 4B
chr14_+_58637934 0.11 ENST00000395153.8
dishevelled binding antagonist of beta catenin 1
chr12_+_12611839 0.11 ENST00000228865.3
cAMP responsive element binding protein like 2
chr3_+_181711915 0.11 ENST00000325404.3
SRY-box transcription factor 2
chr6_-_11044275 0.11 ENST00000354666.4
ELOVL fatty acid elongase 2
chr2_-_68252482 0.10 ENST00000234310.8
protein phosphatase 3 regulatory subunit B, alpha
chr19_+_58033999 0.10 ENST00000282326.6
ENST00000391700.5
zinc finger and SCAN domain containing 1
chr12_-_124567464 0.10 ENST00000458234.5
nuclear receptor corepressor 2
chr4_-_36244438 0.10 ENST00000303965.9
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr17_-_3668640 0.10 ENST00000611779.4
Tax1 binding protein 3
chr9_-_34458533 0.10 ENST00000379089.5
ENST00000379087.5
ENST00000379084.5
ENST00000379081.5
ENST00000379080.5
ENST00000422409.5
ENST00000379078.1
ENST00000651358.1
ENST00000445726.5
ENST00000297620.8
family with sequence similarity 219 member A
chrX_-_19122457 0.10 ENST00000357991.7
ENST00000356606.8
ENST00000379869.8
adhesion G protein-coupled receptor G2
chr8_-_123241336 0.10 ENST00000276704.6
chromosome 8 open reading frame 76
chr20_+_47501875 0.10 ENST00000371998.8
ENST00000372004.7
nuclear receptor coactivator 3
chr7_-_8262668 0.10 ENST00000446305.1
islet cell autoantigen 1
chrX_+_106920393 0.10 ENST00000336803.2
claudin 2
chr1_-_11691471 0.10 ENST00000376672.5
mitotic arrest deficient 2 like 2
chr6_+_391743 0.10 ENST00000380956.9
interferon regulatory factor 4
chr17_-_42609356 0.10 ENST00000309428.10
reticulophagy regulator family member 3
chr14_-_88554898 0.10 ENST00000556564.6
protein tyrosine phosphatase non-receptor type 21
chr12_-_53220377 0.10 ENST00000543726.1
retinoic acid receptor gamma
chr10_-_77637558 0.09 ENST00000372421.10
ENST00000639370.1
ENST00000640773.1
ENST00000638895.1
potassium calcium-activated channel subfamily M alpha 1
chr1_-_153986329 0.09 ENST00000368575.5
RAB13, member RAS oncogene family
chr15_-_78620964 0.09 ENST00000326828.6
cholinergic receptor nicotinic alpha 3 subunit
chrX_+_19343893 0.09 ENST00000540249.5
ENST00000545074.5
ENST00000379806.9
ENST00000423505.5
ENST00000422285.7
ENST00000417819.5
ENST00000355808.9
ENST00000379805.3
pyruvate dehydrogenase E1 subunit alpha 1
chr21_-_14383125 0.09 ENST00000285667.4
heat shock protein family A (Hsp70) member 13
chr1_-_94927079 0.09 ENST00000370206.9
ENST00000394202.8
calponin 3
chr2_-_65432591 0.09 ENST00000356388.9
sprouty related EVH1 domain containing 2
chr12_-_42238203 0.09 ENST00000327791.8
ENST00000534854.7
YY1 associated factor 2
chr19_-_18606779 0.09 ENST00000684169.1
ENST00000392386.8
cytokine receptor like factor 1
chr5_+_93583212 0.08 ENST00000327111.8
nuclear receptor subfamily 2 group F member 1
chr17_+_78169127 0.08 ENST00000590201.1
synaptogyrin 2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
0.2 0.6 GO:1900111 positive regulation of histone H3-K9 dimethylation(GO:1900111)
0.1 0.4 GO:0021897 forebrain astrocyte differentiation(GO:0021896) forebrain astrocyte development(GO:0021897)
0.1 1.9 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 1.8 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 0.1 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.1 0.6 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.1 0.7 GO:2000860 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.1 0.4 GO:1904674 positive regulation of somatic stem cell population maintenance(GO:1904674)
0.1 0.5 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.1 0.6 GO:0071896 protein localization to adherens junction(GO:0071896)
0.1 0.2 GO:0045196 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200) establishment of protein localization to endoplasmic reticulum membrane(GO:0097051)
0.1 0.4 GO:0060214 endocardium formation(GO:0060214)
0.1 0.5 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.1 0.2 GO:0098905 pulmonary valve formation(GO:0003193) foramen ovale closure(GO:0035922) regulation of bundle of His cell action potential(GO:0098905)
0.1 0.6 GO:0035865 cellular response to potassium ion(GO:0035865)
0.1 0.2 GO:0000961 negative regulation of mitochondrial RNA catabolic process(GO:0000961)
0.0 0.2 GO:0061152 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.0 0.2 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.0 0.2 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0 0.3 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.0 0.2 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
0.0 0.2 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0 0.2 GO:0070778 L-aspartate transport(GO:0070778) L-aspartate transmembrane transport(GO:0089712)
0.0 0.2 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.0 0.1 GO:0060903 germ-line stem cell population maintenance(GO:0030718) positive regulation of meiosis I(GO:0060903)
0.0 0.3 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.0 0.2 GO:0035624 receptor transactivation(GO:0035624)
0.0 0.1 GO:0032904 viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.0 0.2 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.1 GO:0030961 peptidyl-arginine hydroxylation(GO:0030961)
0.0 0.1 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.0 0.4 GO:0023035 CD40 signaling pathway(GO:0023035)
0.0 0.1 GO:0006447 regulation of translational initiation by iron(GO:0006447)
0.0 0.2 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 0.1 GO:1901382 chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382)
0.0 0.5 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.0 0.3 GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.0 0.6 GO:0010867 positive regulation of triglyceride biosynthetic process(GO:0010867)
0.0 0.5 GO:0051531 NFAT protein import into nucleus(GO:0051531)
0.0 0.2 GO:0061181 regulation of chondrocyte development(GO:0061181)
0.0 0.1 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.0 0.1 GO:1902463 protein localization to cell leading edge(GO:1902463)
0.0 0.2 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.0 0.1 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.0 0.1 GO:0048619 embryonic hindgut morphogenesis(GO:0048619)
0.0 0.1 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.0 0.1 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.0 0.2 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.0 0.1 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.1 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.0 0.2 GO:0021769 orbitofrontal cortex development(GO:0021769)
0.0 0.1 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.0 0.1 GO:1903984 rhythmic synaptic transmission(GO:0060024) negative regulation of ribosome biogenesis(GO:0090071) positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.0 0.4 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.3 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.1 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
0.0 0.7 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.0 0.1 GO:1900147 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.0 0.1 GO:0001866 NK T cell proliferation(GO:0001866)
0.0 0.3 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.2 GO:0072718 response to cisplatin(GO:0072718)
0.0 0.1 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.3 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 1.0 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.9 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.3 GO:0051660 establishment of centrosome localization(GO:0051660)
0.0 0.3 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.1 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.0 0.1 GO:0015808 L-alanine transport(GO:0015808)
0.0 0.1 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.1 GO:0031119 rRNA pseudouridine synthesis(GO:0031118) tRNA pseudouridine synthesis(GO:0031119)
0.0 0.2 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 0.0 GO:0090096 regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
0.0 0.3 GO:0051450 myoblast proliferation(GO:0051450)
0.0 0.2 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.3 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.0 GO:0033693 neurofilament bundle assembly(GO:0033693)
0.0 0.0 GO:0001579 medium-chain fatty acid transport(GO:0001579)
0.0 0.2 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.1 GO:0071286 cellular response to magnesium ion(GO:0071286)
0.0 0.2 GO:2000615 regulation of histone H3-K9 acetylation(GO:2000615)
0.0 0.4 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.1 GO:0001714 endodermal cell fate specification(GO:0001714)
0.0 0.1 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0 0.0 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.1 0.5 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.1 0.6 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.1 0.6 GO:0044530 supraspliceosomal complex(GO:0044530)
0.1 1.9 GO:0043194 axon initial segment(GO:0043194)
0.0 0.2 GO:0045160 myosin I complex(GO:0045160)
0.0 0.2 GO:0036398 TCR signalosome(GO:0036398)
0.0 0.3 GO:0098560 cytoplasmic side of early endosome membrane(GO:0098559) cytoplasmic side of late endosome membrane(GO:0098560)
0.0 0.1 GO:0010370 perinucleolar chromocenter(GO:0010370)
0.0 0.2 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.1 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.0 0.1 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.0 0.2 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.0 0.3 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.1 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.6 GO:0001741 XY body(GO:0001741)
0.0 0.2 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.6 GO:0005916 fascia adherens(GO:0005916)
0.0 1.7 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.2 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.3 GO:0032059 bleb(GO:0032059)
0.0 0.4 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.1 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.2 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.3 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.2 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.2 GO:0031010 ISWI-type complex(GO:0031010)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 2.4 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1 0.6 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.1 0.6 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1 0.3 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.2 GO:0086020 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020)
0.0 0.8 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 1.0 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.2 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.5 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.0 0.1 GO:0034584 piRNA binding(GO:0034584)
0.0 0.3 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.1 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.0 1.1 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.7 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.1 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.0 0.2 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.0 0.2 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.1 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0 0.1 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
0.0 0.3 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.6 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.4 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.1 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.1 GO:0051717 inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity(GO:0051717) phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.2 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.2 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609) adenosine receptor binding(GO:0031685)
0.0 0.1 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.2 GO:0030284 estrogen receptor activity(GO:0030284)
0.0 0.3 GO:0008061 chitin binding(GO:0008061)
0.0 0.1 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.2 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.1 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.1 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.0 0.0 GO:0003941 L-serine ammonia-lyase activity(GO:0003941)
0.0 0.1 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.2 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.2 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.2 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0 0.3 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.3 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.2 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.0 0.1 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.1 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.3 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.1 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.0 0.1 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 1.0 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 1.0 PID CDC42 REG PATHWAY Regulation of CDC42 activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.7 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 1.1 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.3 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 1.1 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 1.7 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.6 REACTOME NCAM SIGNALING FOR NEURITE OUT GROWTH Genes involved in NCAM signaling for neurite out-growth
0.0 0.5 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.4 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.4 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.2 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.1 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network