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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for NR1H4

Z-value: 0.51

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Transcription factors associated with NR1H4

Gene Symbol Gene ID Gene Info
ENSG00000012504.15 NR1H4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR1H4hg38_v1_chr12_+_100473916_1004739270.222.8e-01Click!

Activity profile of NR1H4 motif

Sorted Z-values of NR1H4 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of NR1H4

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr1_+_61082398 1.53 ENST00000664149.1
nuclear factor I A
chr14_+_76761453 1.36 ENST00000167106.9
vasohibin 1
chr1_+_61082702 1.22 ENST00000485903.6
ENST00000371185.6
ENST00000371184.6
nuclear factor I A
chr1_+_61082553 1.21 ENST00000403491.8
ENST00000371187.7
nuclear factor I A
chr1_+_162381703 0.99 ENST00000458626.4
chromosome 1 open reading frame 226
chr11_-_89491320 0.82 ENST00000534731.5
ENST00000527626.5
ENST00000525196.5
ENST00000263317.9
NADPH oxidase 4
chr1_+_31576485 0.81 ENST00000457433.6
ENST00000271064.12
tubulointerstitial nephritis antigen like 1
chr12_-_56333893 0.73 ENST00000547572.1
ENST00000257931.9
ENST00000610546.4
ENST00000440411.7
poly(A) specific ribonuclease subunit PAN2
chr19_+_35031263 0.66 ENST00000640135.1
ENST00000596348.2
sodium voltage-gated channel beta subunit 1
chr12_-_56333693 0.65 ENST00000425394.7
ENST00000548043.5
poly(A) specific ribonuclease subunit PAN2
chr9_+_71911468 0.61 ENST00000377031.7
chromosome 9 open reading frame 85
chr3_-_28348805 0.61 ENST00000457172.5
ENST00000479665.6
5-azacytidine induced 2
chr17_-_38563986 0.60 ENST00000622519.4
SRC kinase signaling inhibitor 1
chr11_-_89491131 0.57 ENST00000343727.9
ENST00000531342.5
ENST00000375979.7
NADPH oxidase 4
chr10_-_93601228 0.56 ENST00000371464.8
retinol binding protein 4
chr17_-_55732074 0.54 ENST00000575734.5
transmembrane protein 100
chr6_-_109094819 0.51 ENST00000436639.6
sestrin 1
chr5_+_141199555 0.50 ENST00000624887.1
ENST00000354757.5
protocadherin beta 11
chr3_+_52794768 0.48 ENST00000621946.4
ENST00000416872.6
ENST00000449956.2
inter-alpha-trypsin inhibitor heavy chain 3
chr3_+_124384950 0.48 ENST00000683146.1
kalirin RhoGEF kinase
chr7_+_94509793 0.46 ENST00000297273.9
CAS1 domain containing 1
chr22_+_29307005 0.46 ENST00000406549.7
ENST00000610653.4
ENST00000621062.4
ENST00000611648.2
ENST00000618518.3
growth arrest specific 2 like 1
chr3_-_160399207 0.44 ENST00000465537.5
ENST00000486856.5
ENST00000468218.5
ENST00000478370.5
ENST00000326448.12
intraflagellar transport 80
chrX_+_70234655 0.44 ENST00000374521.4
acyl-CoA wax alcohol acyltransferase 1
chr10_-_73874568 0.44 ENST00000322635.7
ENST00000322680.7
ENST00000394762.7
ENST00000680035.1
calcium/calmodulin dependent protein kinase II gamma
chrX_-_21758097 0.43 ENST00000379494.4
small muscle protein X-linked
chr22_+_30694851 0.42 ENST00000332585.11
oxysterol binding protein 2
chr1_-_6497096 0.41 ENST00000537245.6
pleckstrin homology and RhoGEF domain containing G5
chr6_+_95577465 0.41 ENST00000369293.6
ENST00000683151.1
ENST00000358812.9
mannosidase endo-alpha
chr1_+_26543106 0.40 ENST00000530003.5
ribosomal protein S6 kinase A1
chr6_+_107028188 0.40 ENST00000311381.8
ENST00000405204.6
mitochondrial transcription rescue factor 1
chr3_+_124384513 0.39 ENST00000682540.1
ENST00000522553.6
ENST00000682695.1
ENST00000682674.1
ENST00000684382.1
kalirin RhoGEF kinase
chr17_-_75979117 0.39 ENST00000301608.8
ENST00000293217.10
ENST00000588176.5
acyl-CoA oxidase 1
chr4_+_25914171 0.39 ENST00000506197.2
small integral membrane protein 20
chr2_+_32946944 0.39 ENST00000404816.7
latent transforming growth factor beta binding protein 1
chr4_+_25914275 0.39 ENST00000514384.1
small integral membrane protein 20
chr12_-_15882261 0.38 ENST00000646918.1
ENST00000647087.1
ENST00000535752.5
epidermal growth factor receptor pathway substrate 8
chr11_-_6320494 0.38 ENST00000303927.4
ENST00000530979.1
caveolae associated protein 3
chr1_-_225428813 0.38 ENST00000338179.6
ENST00000425080.1
lamin B receptor
chr3_+_28348695 0.37 ENST00000383768.7
zinc finger CW-type and PWWP domain containing 2
chr1_+_85580751 0.36 ENST00000451137.7
cellular communication network factor 1
chr19_-_14090963 0.34 ENST00000269724.5
sterile alpha motif domain containing 1
chr11_+_7251886 0.34 ENST00000318881.11
synaptotagmin 9
chr14_+_85533167 0.34 ENST00000682132.1
fibronectin leucine rich transmembrane protein 2
chr14_-_24634160 0.33 ENST00000616551.1
ENST00000382542.5
ENST00000216341.9
ENST00000526004.1
ENST00000415355.7
granzyme B
chr3_-_28348924 0.32 ENST00000414162.5
ENST00000420543.6
5-azacytidine induced 2
chr14_-_24634266 0.32 ENST00000382540.5
granzyme B
chr10_-_73874502 0.32 ENST00000372765.5
ENST00000351293.7
ENST00000441192.2
ENST00000423381.6
calcium/calmodulin dependent protein kinase II gamma
chr19_-_48363914 0.31 ENST00000377431.6
ENST00000293261.8
transmembrane protein 143
chrX_+_7219431 0.30 ENST00000674499.1
ENST00000217961.5
steroid sulfatase
chr21_+_46001300 0.29 ENST00000612273.2
ENST00000682634.1
collagen type VI alpha 1 chain
chr6_+_127266832 0.29 ENST00000356799.6
ENST00000368314.6
ring finger protein 146
chr1_-_53945567 0.28 ENST00000371378.6
heat shock protein family B (small) member 11
chr1_-_53945584 0.28 ENST00000371377.3
heat shock protein family B (small) member 11
chr14_-_54441325 0.28 ENST00000556113.1
ENST00000553660.5
ENST00000216416.9
ENST00000395573.8
ENST00000557690.5
cornichon family AMPA receptor auxiliary protein 1
chr3_+_184155310 0.27 ENST00000313143.9
dishevelled segment polarity protein 3
chr14_-_34462223 0.27 ENST00000298130.5
serine palmitoyltransferase small subunit A
chr19_-_48364034 0.27 ENST00000435956.7
transmembrane protein 143
chr3_-_28348629 0.26 ENST00000334100.10
5-azacytidine induced 2
chr14_-_21024092 0.26 ENST00000554398.5
NDRG family member 2
chr6_+_127266875 0.26 ENST00000610162.5
ENST00000608991.5
ENST00000610153.1
ring finger protein 146
chr17_-_45490696 0.25 ENST00000430334.8
ENST00000584420.1
ENST00000589780.5
pleckstrin homology and RUN domain containing M1
chr1_+_12063357 0.25 ENST00000417814.3
TNF receptor superfamily member 8
chr19_-_49808639 0.25 ENST00000529634.2
fuzzy planar cell polarity protein
chr1_+_12063285 0.25 ENST00000263932.7
TNF receptor superfamily member 8
chr7_-_150341615 0.25 ENST00000223271.8
ENST00000466675.5
ENST00000482669.1
ENST00000467793.5
retinoic acid receptor responder 2
chr17_+_35809474 0.24 ENST00000604879.5
ENST00000603427.5
ENST00000603777.5
ENST00000605844.6
ENST00000604841.5
TATA-box binding protein associated factor 15
chr6_+_44158807 0.24 ENST00000532171.5
ENST00000398776.2
calpain 11
chr5_+_141208697 0.24 ENST00000624949.1
ENST00000622978.1
ENST00000239450.4
protocadherin beta 12
chr2_-_74147868 0.24 ENST00000295326.4
ENST00000327428.10
bolA family member 3
chr3_-_57079287 0.23 ENST00000338458.8
ENST00000468727.5
Rho guanine nucleotide exchange factor 3
chr19_-_44356664 0.23 ENST00000354340.9
ENST00000337401.8
ENST00000587909.1
zinc finger protein 112
chr7_-_29990113 0.23 ENST00000426154.5
ENST00000421434.5
ENST00000434476.6
secernin 1
chr14_-_21023954 0.22 ENST00000554094.5
NDRG family member 2
chr3_+_160399630 0.22 ENST00000465903.5
ENST00000485645.5
ENST00000472991.5
ENST00000467468.5
ENST00000469762.5
ENST00000357388.8
ENST00000489573.5
ENST00000462787.5
ENST00000490207.5
ENST00000485867.5
structural maintenance of chromosomes 4
chrX_+_153072454 0.21 ENST00000421798.5
PNMA family member 6A
chr2_+_237692290 0.21 ENST00000420665.5
ENST00000392000.4
LRR binding FLII interacting protein 1
chr10_-_118046574 0.21 ENST00000369199.5
RAB11 family interacting protein 2
chr3_-_160399512 0.21 ENST00000498409.5
ENST00000475677.5
ENST00000478536.1
intraflagellar transport 80
chr2_+_176151543 0.20 ENST00000306324.4
homeobox D4
chr3_-_49021045 0.20 ENST00000440857.5
DALR anticodon binding domain containing 3
chr1_+_25272479 0.20 ENST00000622561.4
Rh blood group D antigen
chr2_-_74553049 0.19 ENST00000409549.5
lysyl oxidase like 3
chr1_-_109041986 0.19 ENST00000400794.7
ENST00000528747.1
ENST00000361054.7
WD repeat domain 47
chr19_-_35812838 0.19 ENST00000653904.2
proline dehydrogenase 2
chr10_-_118046922 0.19 ENST00000355624.8
RAB11 family interacting protein 2
chr1_+_25272502 0.19 ENST00000328664.9
Rh blood group D antigen
chr1_-_109042093 0.19 ENST00000369962.8
ENST00000357672.7
ENST00000531337.1
ENST00000529074.1
ENST00000369965.8
WD repeat domain 47
chr3_+_124384757 0.19 ENST00000684374.1
kalirin RhoGEF kinase
chr20_-_3663399 0.18 ENST00000290417.7
ENST00000319242.8
GDNF family receptor alpha 4
chr1_+_26234157 0.18 ENST00000640292.2
ENST00000451429.8
ENST00000252992.8
centrosomal protein 85
chr3_-_47443092 0.18 ENST00000545718.2
ENST00000495603.2
SREBF chaperone
chr11_-_62612725 0.18 ENST00000419857.1
ENST00000394773.7
EMAP like 3
chr1_-_23825402 0.17 ENST00000235958.4
ENST00000436439.6
ENST00000374490.8
3-hydroxy-3-methylglutaryl-CoA lyase
chr19_-_11578937 0.17 ENST00000592659.1
ENST00000592828.6
ENST00000218758.9
ENST00000412435.6
acid phosphatase 5, tartrate resistant
chr3_+_190388120 0.17 ENST00000456423.2
ENST00000264734.3
claudin 16
chr22_+_29767351 0.17 ENST00000330029.6
ENST00000401406.3
ubiquinol-cytochrome c reductase, complex III subunit X
chr19_+_50203607 0.17 ENST00000642316.2
ENST00000425460.6
ENST00000440075.6
ENST00000376970.6
ENST00000599920.5
myosin heavy chain 14
chr5_-_177996242 0.17 ENST00000308304.2
PROP paired-like homeobox 1
chr5_+_139293728 0.17 ENST00000510056.5
ENST00000511249.5
ENST00000394805.8
ENST00000503811.5
ENST00000618441.5
matrin 3
chr19_+_40611863 0.17 ENST00000601032.5
latent transforming growth factor beta binding protein 4
chr17_-_28711660 0.17 ENST00000439862.7
ENST00000581289.1
ENST00000301039.6
ENST00000682792.1
protein interacting with cyclin A1
chr17_-_61863327 0.16 ENST00000584322.2
ENST00000682369.1
ENST00000683039.1
ENST00000683381.1
BRCA1 interacting protein C-terminal helicase 1
chr16_+_66961242 0.16 ENST00000394037.5
ENST00000303334.9
carboxylesterase 3
chr13_-_32538819 0.16 ENST00000674452.1
ENST00000674422.1
ENST00000674349.1
ENST00000674465.1
ENST00000674327.1
ENST00000505213.5
ENST00000357505.10
ENST00000399396.7
NEDD4 binding protein 2 like 2
chr12_-_70609788 0.16 ENST00000547715.1
ENST00000538708.5
ENST00000550857.5
ENST00000261266.9
protein tyrosine phosphatase receptor type B
chr19_+_1071194 0.16 ENST00000543365.5
Rho GTPase activating protein 45
chr1_+_103525690 0.15 ENST00000524631.5
ENST00000531883.5
ENST00000533099.5
ENST00000423855.7
ENST00000527062.5
RNA binding region (RNP1, RRM) containing 3
chr11_+_62613236 0.15 ENST00000278833.4
retinal outer segment membrane protein 1
chr17_-_61863452 0.15 ENST00000683672.1
ENST00000682989.1
ENST00000682453.1
ENST00000259008.7
ENST00000577913.2
BRCA1 interacting protein C-terminal helicase 1
chr1_+_156054761 0.15 ENST00000368305.9
ENST00000368304.9
ENST00000368302.3
late endosomal/lysosomal adaptor, MAPK and MTOR activator 2
chr22_+_20967212 0.15 ENST00000434714.6
apoptosis inducing factor mitochondria associated 3
chr18_+_3448456 0.15 ENST00000549780.5
TGFB induced factor homeobox 1
chr1_+_25272492 0.14 ENST00000454452.6
Rh blood group D antigen
chr18_+_56651335 0.14 ENST00000589935.1
ENST00000254442.8
ENST00000357574.7
WD repeat domain 7
chr5_+_139293700 0.14 ENST00000504045.5
ENST00000504311.5
ENST00000502499.5
matrin 3
chr3_-_50345665 0.14 ENST00000442887.1
ENST00000231749.8
ENST00000360165.7
zinc finger MYND-type containing 10
chr3_-_197749688 0.14 ENST00000273582.9
rubicon autophagy regulator
chr11_-_10858046 0.14 ENST00000413761.7
ENST00000528289.5
ENST00000432999.6
zinc finger BED-type containing 5
chr11_-_58578096 0.14 ENST00000528954.5
ENST00000528489.1
leupaxin
chr4_-_169757873 0.14 ENST00000393381.3
histone PARylation factor 1
chr7_+_49773632 0.14 ENST00000340652.5
von Willebrand factor C domain containing 2
chr9_-_134917872 0.14 ENST00000616356.4
ENST00000371806.4
ficolin 1
chr12_-_57520480 0.13 ENST00000642841.1
ENST00000547303.5
ENST00000552740.5
ENST00000547526.1
ENST00000346473.8
ENST00000551116.5
novel protein
DNA damage inducible transcript 3
chr14_-_24084625 0.13 ENST00000397002.6
neural retina leucine zipper
chr3_+_119147375 0.13 ENST00000490594.2
novel chromosome 3 open reading frame 30 (C3orf30) and uroplakin 1B (UPK1B)
chr4_+_122152308 0.13 ENST00000679879.1
ENST00000264501.8
KIAA1109
chr2_+_70900546 0.13 ENST00000234392.3
ventral anterior homeobox 2
chr17_-_76027296 0.13 ENST00000301607.8
envoplakin
chr5_-_16508812 0.13 ENST00000683414.1
reticulophagy regulator 1
chr3_+_54123452 0.13 ENST00000620722.4
ENST00000490478.5
calcium voltage-gated channel auxiliary subunit alpha2delta 3
chr17_+_17681449 0.12 ENST00000353383.6
retinoic acid induced 1
chr1_-_50023875 0.12 ENST00000371836.1
ENST00000371838.5
ATP/GTP binding protein like 4
chr1_+_25272527 0.12 ENST00000342055.9
ENST00000357542.8
ENST00000417538.6
ENST00000423810.6
ENST00000568195.5
Rh blood group D antigen
chr5_+_32710630 0.12 ENST00000326958.5
natriuretic peptide receptor 3
chr11_+_67483019 0.12 ENST00000279146.8
ENST00000528641.7
ENST00000682324.1
ENST00000684006.1
ENST00000683237.1
ENST00000684657.1
aryl hydrocarbon receptor interacting protein
chr22_+_30694886 0.11 ENST00000446658.6
oxysterol binding protein 2
chr3_+_184155451 0.11 ENST00000431765.6
dishevelled segment polarity protein 3
chr19_+_35138778 0.11 ENST00000351325.9
ENST00000586871.5
ENST00000592174.1
FXYD domain containing ion transport regulator 1
novel transcript
chr19_+_10452891 0.11 ENST00000344979.7
phosphodiesterase 4A
chrX_+_118727575 0.11 ENST00000371642.1
ENST00000371666.8
interleukin 13 receptor subunit alpha 1
chr20_-_56525925 0.11 ENST00000243913.8
glucosaminyl (N-acetyl) transferase family member 7
chr6_-_49713521 0.11 ENST00000339139.5
cysteine rich secretory protein 2
chr17_-_64230727 0.10 ENST00000583097.5
ENST00000615733.4
testis expressed 2
chr6_-_24719146 0.10 ENST00000378119.9
chromosome 6 open reading frame 62
chr7_-_151024423 0.10 ENST00000469530.4
ENST00000639579.1
autophagy related 9B
chr3_-_49120785 0.10 ENST00000417901.5
ENST00000306026.5
ENST00000434032.6
ubiquitin specific peptidase 19
chr6_+_30626842 0.10 ENST00000318999.11
ENST00000376485.8
ENST00000330083.6
ENST00000319027.9
ENST00000376483.8
ENST00000329992.12
alpha tubulin acetyltransferase 1
chr17_-_28552549 0.10 ENST00000581945.1
ENST00000444148.1
ENST00000335765.9
ENST00000301032.8
unc-119 lipid binding chaperone
chr5_+_139293939 0.10 ENST00000508689.1
ENST00000514528.5
matrin 3
chr3_-_49120887 0.09 ENST00000453664.5
ENST00000398888.6
ubiquitin specific peptidase 19
chr5_-_16508858 0.09 ENST00000684456.1
reticulophagy regulator 1
chr5_-_16508951 0.09 ENST00000682628.1
reticulophagy regulator 1
chr4_-_174263080 0.09 ENST00000615392.4
F-box protein 8
chr5_+_80319997 0.09 ENST00000296739.6
spermatogenic leucine zipper 1
chr22_-_29838227 0.09 ENST00000307790.8
ENST00000397771.6
ENST00000542393.5
activating signal cointegrator 1 complex subunit 2
chr5_-_73448769 0.09 ENST00000615637.3
forkhead box D1
chr2_-_46915745 0.09 ENST00000649435.1
ENST00000409105.5
ENST00000319466.9
ENST00000409973.5
ENST00000409913.5
multiple coagulation factor deficiency 2, ER cargo receptor complex subunit
chr19_-_18274411 0.09 ENST00000595654.6
ENST00000593659.5
ENST00000599528.1
ENST00000392413.5
ENST00000608950.1
ENST00000600328.7
ENST00000600359.7
ENST00000612316.4
IQ motif containing N
chr2_-_46916020 0.08 ENST00000409800.5
ENST00000409218.5
multiple coagulation factor deficiency 2, ER cargo receptor complex subunit
chr6_+_151690492 0.08 ENST00000404742.5
ENST00000440973.5
estrogen receptor 1
chr9_+_81928428 0.08 ENST00000419782.5
SPATA31 subfamily D member 4
chr1_+_32765667 0.08 ENST00000373480.1
KIAA1522
chrX_-_119693150 0.08 ENST00000394610.7
septin 6
chr1_+_178513103 0.08 ENST00000319416.7
ENST00000367643.7
ENST00000367642.3
ENST00000367641.7
ENST00000367639.1
testis expressed 35
chr17_-_42745025 0.08 ENST00000592492.5
ENST00000585893.5
ENST00000593214.5
ENST00000590078.5
ENST00000428826.7
ENST00000586382.5
ENST00000415827.6
ENST00000592743.5
ENST00000586089.5
enhancer of zeste 1 polycomb repressive complex 2 subunit
chr12_+_108880085 0.07 ENST00000228476.8
ENST00000547768.5
D-amino acid oxidase
chr17_+_61452378 0.07 ENST00000589003.5
ENST00000644296.1
T-box transcription factor 4
chr12_+_51912329 0.07 ENST00000547400.5
ENST00000550683.5
ENST00000419526.6
activin A receptor like type 1
chr10_+_62804710 0.07 ENST00000373783.3
2-aminoethanethiol dioxygenase
chr20_+_32052192 0.07 ENST00000375862.7
ENST00000629881.2
ENST00000375852.5
ENST00000520553.5
ENST00000518730.5
HCK proto-oncogene, Src family tyrosine kinase
chr5_+_139293660 0.07 ENST00000512876.5
ENST00000513678.5
matrin 3
chr7_-_78771265 0.07 ENST00000630991.2
ENST00000629359.2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr5_+_138084015 0.07 ENST00000504809.5
ENST00000506684.6
ENST00000398754.1
Wnt family member 8A
chr2_-_218568291 0.07 ENST00000418019.5
ENST00000454775.5
ENST00000338465.5
ENST00000415516.5
ENST00000258399.8
ubiquitin specific peptidase 37
chr17_+_47209035 0.06 ENST00000572316.5
ENST00000354968.5
ENST00000576874.5
ENST00000536623.6
myosin light chain 4
chr17_-_76027212 0.06 ENST00000586740.1
envoplakin
chr17_-_28854972 0.06 ENST00000583953.6
family with sequence similarity 222 member B
chr17_-_46818680 0.06 ENST00000225512.6
Wnt family member 3
chr9_-_89178810 0.06 ENST00000375835.9
SHC adaptor protein 3
chr8_-_130016622 0.05 ENST00000518283.5
ENST00000519110.5
CYFIP related Rac1 interactor B
chr19_-_3063101 0.05 ENST00000221561.12
TLE family member 5, transcriptional modulator
chr19_-_10503186 0.05 ENST00000592055.2
ENST00000171111.10
kelch like ECH associated protein 1
chr3_+_50569470 0.05 ENST00000455834.5
ENST00000232854.9
HemK methyltransferase family member 1
chr11_+_67483119 0.05 ENST00000682659.1
ENST00000525341.2
aryl hydrocarbon receptor interacting protein
chr6_+_31655888 0.05 ENST00000375916.4
apolipoprotein M
chr22_+_31753867 0.05 ENST00000535622.6
ENST00000645693.1
ENST00000642974.1
ENST00000645711.1
ENST00000644331.1
ENST00000645560.1
ENST00000437411.6
ENST00000433147.2
ENST00000646755.1
ENST00000382112.8
ENST00000647438.1
ENST00000400248.7
ENST00000456178.6
ENST00000646969.1
ENST00000642696.1
ENST00000647343.1
ENST00000400242.8
ENST00000651528.2
ENST00000645015.1
ENST00000645564.1
ENST00000646465.1
ENST00000400249.7
DEP domain containing 5, GATOR1 subcomplex subunit
chr1_+_22563460 0.05 ENST00000166244.8
ENST00000374644.8
EPH receptor A8
chr15_+_65869974 0.05 ENST00000567671.1
RAB11A, member RAS oncogene family
chr16_-_67666692 0.05 ENST00000602644.5
ENST00000243878.9
enkurin domain containing 1
chr2_+_108288869 0.04 ENST00000251481.11
ENST00000438339.5
ENST00000409880.5
ENST00000437390.6
sulfotransferase family 1C member 2
chr17_-_64130125 0.04 ENST00000680433.1
ENST00000433197.4
endoplasmic reticulum to nucleus signaling 1
chr9_-_68540879 0.04 ENST00000377311.4
transmembrane protein 252
chr13_+_30617902 0.04 ENST00000255304.9
ENST00000614860.1
ubiquitin specific peptidase like 1
chr19_-_35135180 0.04 ENST00000392225.7
leucine rich repeat LGI family member 4
chr8_-_56446572 0.04 ENST00000518974.5
ENST00000451791.7
ENST00000523051.5
ENST00000518770.1
proenkephalin
chr17_-_75261586 0.04 ENST00000580799.2
ENST00000538886.5
ENST00000537686.6
golgi associated, gamma adaptin ear containing, ARF binding protein 3
chr20_-_45667177 0.04 ENST00000618797.4
WAP four-disulfide core domain 11
chr7_+_2632029 0.04 ENST00000407643.5
tweety family member 3
chr8_-_130016414 0.04 ENST00000401979.6
ENST00000517654.5
ENST00000522361.1
ENST00000518167.5
CYFIP related Rac1 interactor B

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.2 1.2 GO:0044565 dendritic cell proliferation(GO:0044565)
0.2 0.5 GO:0045556 TRAIL biosynthetic process(GO:0045553) regulation of TRAIL biosynthetic process(GO:0045554) positive regulation of TRAIL biosynthetic process(GO:0045556)
0.1 0.4 GO:0043465 fermentation(GO:0006113) regulation of fermentation(GO:0043465)
0.1 4.0 GO:0072189 ureter development(GO:0072189)
0.1 0.7 GO:0021966 corticospinal neuron axon guidance(GO:0021966)
0.1 1.1 GO:0060125 habituation(GO:0046959) negative regulation of growth hormone secretion(GO:0060125)
0.1 0.6 GO:0048807 female genitalia morphogenesis(GO:0048807)
0.1 0.2 GO:0048850 hypophysis morphogenesis(GO:0048850)
0.1 0.7 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.1 0.3 GO:0000706 meiotic DNA double-strand break processing(GO:0000706) double-strand break repair involved in meiotic recombination(GO:1990918)
0.1 0.4 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 0.4 GO:0010166 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.1 0.3 GO:0006562 proline catabolic process(GO:0006562)
0.1 0.2 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.1 0.3 GO:0090299 regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.1 0.4 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.0 0.2 GO:0061760 antifungal innate immune response(GO:0061760)
0.0 0.4 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.0 0.4 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.0 0.1 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
0.0 0.1 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.0 1.4 GO:0050667 homocysteine metabolic process(GO:0050667)
0.0 0.2 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.8 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617)
0.0 0.5 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.0 0.3 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.0 0.2 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.2 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.0 0.1 GO:0061317 canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:0061317)
0.0 0.1 GO:2001287 negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.0 0.8 GO:1901897 regulation of relaxation of cardiac muscle(GO:1901897)
0.0 0.1 GO:0072268 pattern specification involved in metanephros development(GO:0072268)
0.0 0.5 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 0.6 GO:0070986 left/right axis specification(GO:0070986)
0.0 0.1 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
0.0 0.1 GO:0044805 late nucleophagy(GO:0044805)
0.0 0.2 GO:0090206 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.5 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 1.4 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.0 0.1 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.0 0.1 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.0 0.4 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.2 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551)
0.0 0.2 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0 0.1 GO:0010734 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.0 0.2 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.0 0.1 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.0 0.6 GO:0015695 organic cation transport(GO:0015695)
0.0 0.2 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.2 GO:0051344 negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.0 0.5 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.1 GO:0060061 Spemann organizer formation(GO:0060061)
0.0 0.1 GO:0060750 epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750)
0.0 0.1 GO:0034444 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.0 0.5 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.7 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.1 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.0 0.3 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 0.0 GO:0030576 Cajal body organization(GO:0030576)
0.0 0.1 GO:0035912 dorsal aorta morphogenesis(GO:0035912)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0031251 PAN complex(GO:0031251)
0.1 0.4 GO:0005927 muscle tendon junction(GO:0005927)
0.1 1.4 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.1 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.0 1.2 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.7 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.2 GO:0097513 myosin II filament(GO:0097513)
0.0 0.3 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.5 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.2 GO:0000796 condensin complex(GO:0000796)
0.0 0.7 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.3 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.2 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.5 GO:0097440 apical dendrite(GO:0097440)
0.0 0.1 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.1 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.4 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.4 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.3 GO:0031045 dense core granule(GO:0031045)
0.0 0.1 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.0 0.2 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 GO:0019826 oxygen sensor activity(GO:0019826)
0.1 0.7 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.1 0.4 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.1 0.4 GO:0050436 microfibril binding(GO:0050436)
0.1 0.3 GO:0004773 steryl-sulfatase activity(GO:0004773)
0.1 0.5 GO:0070728 leucine binding(GO:0070728)
0.1 1.4 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 0.8 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.1 0.3 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.2 GO:0004419 hydroxymethylglutaryl-CoA lyase activity(GO:0004419)
0.0 0.4 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.0 0.2 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.5 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.0 0.5 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.2 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.8 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.4 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 0.2 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0 0.5 GO:0019841 retinol binding(GO:0019841)
0.0 1.1 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.2 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.3 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.3 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.5 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.3 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.6 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.0 0.2 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.0 0.1 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.0 0.1 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 0.2 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.1 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.2 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.5 GO:0005109 frizzled binding(GO:0005109)
0.0 0.2 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.0 0.1 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.0 0.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 4.0 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.1 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.8 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.8 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.4 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.5 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.5 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 0.1 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.4 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.3 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.6 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.3 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks