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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for NR2C1

Z-value: 0.97

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Transcription factors associated with NR2C1

Gene Symbol Gene ID Gene Info
NR2C1
ENSG00000120798.17 NR2C1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR2C1hg38_v1_chr12_-_95073490_950735740.611.4e-03Click!

Activity profile of NR2C1 motif

Sorted Z-values of NR2C1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of NR2C1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr6_-_159727324 6.44 ENST00000401980.3
ENST00000545162.5
SOD2
superoxide dismutase 2
chr6_-_159726871 6.05 ENST00000535561.5
SOD2
superoxide dismutase 2
chr2_+_109129199 3.11 ENST00000309415.8
SH3RF3
SH3 domain containing ring finger 3
chr2_+_218568865 2.75 ENST00000295701.9
CNOT9
CCR4-NOT transcription complex subunit 9
chr6_+_159727561 2.68 ENST00000631126.2
ENST00000337387.4
WTAP
WT1 associated protein
chr19_+_10086787 2.62 ENST00000590378.5
ENST00000397881.7
SHFL
shiftless antiviral inhibitor of ribosomal frameshifting
chr6_+_159726998 2.55 ENST00000614346.4
WTAP
WT1 associated protein
chr13_-_33185994 2.11 ENST00000255486.8
STARD13
StAR related lipid transfer domain containing 13
chr19_+_10086305 1.85 ENST00000253110.16
ENST00000591813.5
SHFL
shiftless antiviral inhibitor of ribosomal frameshifting
chr2_+_74529923 1.81 ENST00000258080.8
ENST00000352222.7
HTRA2
HtrA serine peptidase 2
chr3_+_155083523 1.75 ENST00000680057.1
MME
membrane metalloendopeptidase
chr2_+_74530018 1.69 ENST00000437202.1
HTRA2
HtrA serine peptidase 2
chr3_+_155083889 1.67 ENST00000680282.1
MME
membrane metalloendopeptidase
chr19_+_676385 1.46 ENST00000166139.9
FSTL3
follistatin like 3
chr2_+_218568558 1.37 ENST00000627282.2
ENST00000542068.5
CNOT9
CCR4-NOT transcription complex subunit 9
chr19_+_48325323 1.37 ENST00000596315.5
EMP3
epithelial membrane protein 3
chr19_+_48325522 1.36 ENST00000594198.1
ENST00000270221.11
ENST00000597279.5
ENST00000593437.1
EMP3
epithelial membrane protein 3
chr3_-_116444983 1.26 ENST00000333617.8
LSAMP
limbic system associated membrane protein
chr20_+_45857607 1.15 ENST00000255152.3
ZSWIM3
zinc finger SWIM-type containing 3
chr2_+_218568809 1.14 ENST00000273064.11
CNOT9
CCR4-NOT transcription complex subunit 9
chr19_+_50415799 1.12 ENST00000599632.1
ENSG00000142539.9
novel protein
chr11_-_65662931 1.02 ENST00000615805.4
ENST00000612991.4
RELA
RELA proto-oncogene, NF-kB subunit
chr3_-_58627596 1.02 ENST00000474531.5
ENST00000465970.1
FAM107A
family with sequence similarity 107 member A
chr10_+_24466487 1.00 ENST00000396446.5
ENST00000396445.5
ENST00000376451.4
KIAA1217
KIAA1217
chr17_-_37745018 0.96 ENST00000613727.4
ENST00000614313.4
ENST00000617811.5
ENST00000621123.4
HNF1B
HNF1 homeobox B
chr14_-_72894091 0.92 ENST00000556509.6
DPF3
double PHD fingers 3
chr12_+_131929259 0.91 ENST00000542167.2
ENST00000376649.8
ENST00000538037.5
ENST00000456665.6
PUS1
pseudouridine synthase 1
chr11_-_65663083 0.91 ENST00000308639.13
RELA
RELA proto-oncogene, NF-kB subunit
chr7_+_39623886 0.90 ENST00000436179.1
RALA
RAS like proto-oncogene A
chr3_-_58627567 0.88 ENST00000649301.1
FAM107A
family with sequence similarity 107 member A
chr19_+_39125769 0.87 ENST00000602004.1
ENST00000599470.5
ENST00000321944.8
ENST00000593480.5
ENST00000358301.7
ENST00000593690.5
ENST00000599386.5
PAK4
p21 (RAC1) activated kinase 4
chr10_+_26697653 0.85 ENST00000376215.10
PDSS1
decaprenyl diphosphate synthase subunit 1
chr19_-_48868454 0.82 ENST00000355496.9
PLEKHA4
pleckstrin homology domain containing A4
chr3_-_113746218 0.81 ENST00000497255.1
ENST00000240922.8
ENST00000478020.1
ENST00000493900.5
NAA50
N-alpha-acetyltransferase 50, NatE catalytic subunit
chr12_+_131929219 0.80 ENST00000322060.9
PUS1
pseudouridine synthase 1
chr11_-_45918014 0.78 ENST00000525192.5
PEX16
peroxisomal biogenesis factor 16
chr19_-_48868590 0.75 ENST00000263265.11
PLEKHA4
pleckstrin homology domain containing A4
chr1_+_78490966 0.75 ENST00000370757.8
ENST00000370756.3
PTGFR
prostaglandin F receptor
chr2_+_209771972 0.75 ENST00000439458.5
ENST00000272845.10
UNC80
unc-80 homolog, NALCN channel complex subunit
chr11_+_65530639 0.74 ENST00000279270.10
SCYL1
SCY1 like pseudokinase 1
chr3_-_50567646 0.72 ENST00000426034.5
ENST00000441239.5
C3orf18
chromosome 3 open reading frame 18
chr5_-_1801284 0.71 ENST00000505818.1
MRPL36
mitochondrial ribosomal protein L36
chr11_-_45917867 0.69 ENST00000378750.10
PEX16
peroxisomal biogenesis factor 16
chr6_+_43770202 0.68 ENST00000372067.8
ENST00000672860.2
VEGFA
vascular endothelial growth factor A
chr6_+_159727492 0.66 ENST00000621533.5
WTAP
WT1 associated protein
chr17_-_2025289 0.66 ENST00000331238.7
RTN4RL1
reticulon 4 receptor like 1
chr11_-_45917823 0.66 ENST00000533151.5
ENST00000241041.7
PEX16
peroxisomal biogenesis factor 16
chr3_+_184186023 0.65 ENST00000429586.6
ENST00000292808.5
ABCF3
ATP binding cassette subfamily F member 3
chr2_-_162242998 0.64 ENST00000627638.2
ENST00000447386.5
FAP
fibroblast activation protein alpha
chr15_-_82262660 0.64 ENST00000557844.1
ENST00000359445.7
ENST00000268206.12
EFL1
elongation factor like GTPase 1
chrX_+_22136552 0.62 ENST00000682888.1
ENST00000684356.1
PHEX
phosphate regulating endopeptidase homolog X-linked
chr3_-_116445458 0.61 ENST00000490035.7
LSAMP
limbic system associated membrane protein
chr6_+_31547560 0.61 ENST00000376148.9
ENST00000376145.8
NFKBIL1
NFKB inhibitor like 1
chr3_-_126517764 0.60 ENST00000290868.7
UROC1
urocanate hydratase 1
chrX_-_50470818 0.59 ENST00000611977.2
DGKK
diacylglycerol kinase kappa
chr1_-_229434086 0.58 ENST00000366684.7
ENST00000684723.1
ENST00000366683.4
ACTA1
actin alpha 1, skeletal muscle
chr21_+_44012296 0.57 ENST00000291574.9
ENST00000380221.7
TRAPPC10
trafficking protein particle complex 10
chr3_+_37243333 0.56 ENST00000431105.1
GOLGA4
golgin A4
chr3_+_42856021 0.56 ENST00000493193.1
ACKR2
atypical chemokine receptor 2
chr1_+_22052627 0.56 ENST00000400259.5
ENST00000344548.7
ENST00000315554.13
ENST00000656825.1
ENST00000651171.1
ENST00000652582.1
ENST00000667384.1
CDC42
cell division cycle 42
chr3_+_184337591 0.56 ENST00000383847.7
FAM131A
family with sequence similarity 131 member A
chr19_+_16661121 0.55 ENST00000187762.7
ENST00000599479.1
TMEM38A
transmembrane protein 38A
chr8_+_12951583 0.53 ENST00000528753.2
TRMT9B
tRNA methyltransferase 9B (putative)
chr16_-_11915991 0.52 ENST00000420576.6
GSPT1
G1 to S phase transition 1
chr16_+_30699155 0.52 ENST00000262518.9
SRCAP
Snf2 related CREBBP activator protein
chr11_-_67508091 0.51 ENST00000531506.1
CDK2AP2
cyclin dependent kinase 2 associated protein 2
chr2_-_218270099 0.51 ENST00000248450.9
ENST00000444053.5
AAMP
angio associated migratory cell protein
chr2_-_162243375 0.50 ENST00000188790.9
ENST00000443424.5
FAP
fibroblast activation protein alpha
chr21_-_14546351 0.50 ENST00000619120.4
SAMSN1
SAM domain, SH3 domain and nuclear localization signals 1
chr7_+_39623547 0.49 ENST00000005257.7
RALA
RAS like proto-oncogene A
chr21_-_14546297 0.49 ENST00000400566.6
ENST00000400564.5
SAMSN1
SAM domain, SH3 domain and nuclear localization signals 1
chr17_+_73193029 0.49 ENST00000299886.9
ENST00000438720.7
COG1
component of oligomeric golgi complex 1
chr11_-_67508152 0.48 ENST00000301488.8
CDK2AP2
cyclin dependent kinase 2 associated protein 2
chr19_+_6464229 0.47 ENST00000600229.6
ENST00000356762.7
CRB3
crumbs cell polarity complex component 3
chr12_-_48105808 0.46 ENST00000448372.5
SENP1
SUMO specific peptidase 1
chr11_-_134411854 0.45 ENST00000392580.5
B3GAT1
beta-1,3-glucuronyltransferase 1
chr16_-_11915878 0.45 ENST00000439887.6
ENST00000434724.7
GSPT1
G1 to S phase transition 1
chr11_-_116792386 0.44 ENST00000433069.2
ENST00000542499.5
APOA5
apolipoprotein A5
chr20_+_48921701 0.43 ENST00000371917.5
ARFGEF2
ADP ribosylation factor guanine nucleotide exchange factor 2
chr3_+_101827982 0.43 ENST00000461724.5
ENST00000483180.5
ENST00000394054.6
NFKBIZ
NFKB inhibitor zeta
chr12_-_42237727 0.43 ENST00000548917.1
YAF2
YY1 associated factor 2
chr12_-_48106042 0.42 ENST00000551798.1
ENST00000549518.6
SENP1
SUMO specific peptidase 1
chr14_-_21098570 0.42 ENST00000360947.8
ZNF219
zinc finger protein 219
chr2_+_119366924 0.41 ENST00000535757.5
ENST00000535617.5
ENST00000627093.2
ENST00000355857.8
ENST00000409094.5
ENST00000542275.5
ENST00000311521.8
DBI
diazepam binding inhibitor, acyl-CoA binding protein
chr2_-_88128049 0.41 ENST00000393750.3
ENST00000295834.8
FABP1
fatty acid binding protein 1
chrX_+_16786421 0.41 ENST00000398155.4
ENST00000380122.10
TXLNG
taxilin gamma
chr2_-_96035974 0.41 ENST00000434632.5
GPAT2
glycerol-3-phosphate acyltransferase 2, mitochondrial
chr2_-_201451446 0.40 ENST00000332624.8
ENST00000430254.1
TRAK2
trafficking kinesin protein 2
chr20_+_38962299 0.39 ENST00000373325.6
ENST00000373323.8
ENST00000252011.8
ENST00000615559.1
DHX35
ENSG00000277581.1
DEAH-box helicase 35
novel transcript, sense intronic to DHX35
chr8_+_12951325 0.39 ENST00000400069.7
TRMT9B
tRNA methyltransferase 9B (putative)
chr4_-_110623051 0.39 ENST00000557119.2
ENST00000644743.1
PITX2
paired like homeodomain 2
chr14_+_73569115 0.39 ENST00000622407.4
ENST00000238651.10
ACOT2
acyl-CoA thioesterase 2
chr3_-_50567711 0.39 ENST00000357203.8
C3orf18
chromosome 3 open reading frame 18
chr22_-_50527689 0.39 ENST00000652401.1
TYMP
thymidine phosphorylase
chr2_-_42493970 0.39 ENST00000394973.4
ENST00000306078.2
KCNG3
potassium voltage-gated channel modifier subfamily G member 3
chr12_-_42238203 0.38 ENST00000327791.8
ENST00000534854.7
YAF2
YY1 associated factor 2
chr2_+_119367669 0.37 ENST00000393103.2
DBI
diazepam binding inhibitor, acyl-CoA binding protein
chr3_+_37243177 0.36 ENST00000361924.6
ENST00000444882.5
ENST00000356847.8
ENST00000617480.4
ENST00000450863.6
ENST00000429018.5
GOLGA4
golgin A4
chr17_+_4950147 0.35 ENST00000522301.5
ENO3
enolase 3
chr22_-_31140494 0.34 ENST00000215885.4
PLA2G3
phospholipase A2 group III
chr2_-_218269619 0.33 ENST00000447885.1
ENST00000420660.5
AAMP
angio associated migratory cell protein
chr16_-_88686453 0.33 ENST00000332281.6
SNAI3
snail family transcriptional repressor 3
chr21_-_31558977 0.32 ENST00000286827.7
ENST00000541036.5
TIAM1
TIAM Rac1 associated GEF 1
chr4_-_75673112 0.32 ENST00000395719.7
ENST00000677489.1
G3BP2
G3BP stress granule assembly factor 2
chr15_+_90184912 0.30 ENST00000561085.1
ENST00000332496.10
SEMA4B
semaphorin 4B
chr1_-_166975407 0.30 ENST00000528703.5
ENST00000525740.5
ENST00000529387.5
ENST00000469934.6
ENST00000529071.5
ENST00000526687.1
ENST00000271417.8
ILDR2
immunoglobulin like domain containing receptor 2
chr3_-_150546403 0.29 ENST00000239944.7
ENST00000491660.1
ENST00000487153.1
SERP1
stress associated endoplasmic reticulum protein 1
chr10_+_125973373 0.29 ENST00000417114.5
ENST00000445510.5
ENST00000368691.5
FANK1
fibronectin type III and ankyrin repeat domains 1
chr11_-_64246190 0.29 ENST00000392210.6
PPP1R14B
protein phosphatase 1 regulatory inhibitor subunit 14B
chr14_-_21098848 0.28 ENST00000556174.5
ENST00000554478.5
ENST00000553980.1
ENST00000421093.6
ZNF219
zinc finger protein 219
chr11_+_7987314 0.28 ENST00000531572.2
ENST00000651655.1
EIF3F
eukaryotic translation initiation factor 3 subunit F
chr11_-_66438788 0.27 ENST00000329819.4
ENST00000310999.11
ENST00000430466.6
MRPL11
mitochondrial ribosomal protein L11
chr12_+_95858928 0.26 ENST00000266735.9
ENST00000553192.5
ENST00000552085.1
SNRPF
small nuclear ribonucleoprotein polypeptide F
chr7_+_121873152 0.26 ENST00000650826.1
ENST00000650728.1
ENST00000393386.7
ENST00000651390.1
ENST00000651842.1
ENST00000650681.1
PTPRZ1
protein tyrosine phosphatase receptor type Z1
chr19_-_4066892 0.25 ENST00000322357.9
ZBTB7A
zinc finger and BTB domain containing 7A
chr2_-_218568291 0.25 ENST00000418019.5
ENST00000454775.5
ENST00000338465.5
ENST00000415516.5
ENST00000258399.8
USP37
ubiquitin specific peptidase 37
chr2_+_201451711 0.25 ENST00000194530.8
ENST00000392249.6
STRADB
STE20 related adaptor beta
chr17_+_14069489 0.24 ENST00000429152.6
ENST00000261643.8
COX10
cytochrome c oxidase assembly factor heme A:farnesyltransferase COX10
chr16_+_2205708 0.24 ENST00000397124.5
ENST00000565250.1
MLST8
MTOR associated protein, LST8 homolog
chr4_-_75672868 0.23 ENST00000678123.1
ENST00000678578.1
ENST00000677876.1
ENST00000676839.1
ENST00000678265.1
G3BP2
G3BP stress granule assembly factor 2
chr11_+_94768331 0.23 ENST00000317829.12
ENST00000433060.3
AMOTL1
angiomotin like 1
chr14_+_73537135 0.23 ENST00000311148.9
ACOT1
acyl-CoA thioesterase 1
chr4_-_75673139 0.23 ENST00000677566.1
ENST00000503660.5
ENST00000677060.1
ENST00000678552.1
G3BP2
G3BP stress granule assembly factor 2
chr11_-_64245816 0.22 ENST00000542235.1
PPP1R14B
protein phosphatase 1 regulatory inhibitor subunit 14B
chr1_+_160127672 0.22 ENST00000447527.1
ATP1A2
ATPase Na+/K+ transporting subunit alpha 2
chr12_-_22334683 0.22 ENST00000404299.3
ENST00000396037.9
ST8SIA1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
chr9_-_35685462 0.22 ENST00000607559.1
TPM2
tropomyosin 2
chr3_-_113746059 0.21 ENST00000477813.5
NAA50
N-alpha-acetyltransferase 50, NatE catalytic subunit
chr10_+_62804710 0.21 ENST00000373783.3
ADO
2-aminoethanethiol dioxygenase
chr1_-_226186673 0.21 ENST00000366812.6
ACBD3
acyl-CoA binding domain containing 3
chr11_+_65615755 0.21 ENST00000355703.4
PCNX3
pecanex 3
chr7_+_121873089 0.20 ENST00000651065.1
PTPRZ1
protein tyrosine phosphatase receptor type Z1
chr3_-_113746185 0.20 ENST00000616174.1
NAA50
N-alpha-acetyltransferase 50, NatE catalytic subunit
chr3_+_113747022 0.20 ENST00000273398.8
ENST00000496747.5
ENST00000475322.1
ATP6V1A
ATPase H+ transporting V1 subunit A
chr14_+_21768482 0.20 ENST00000390428.3
TRAV6
T cell receptor alpha variable 6
chr2_-_213150236 0.20 ENST00000442445.1
ENST00000342002.6
IKZF2
IKAROS family zinc finger 2
chr4_+_26319636 0.20 ENST00000342295.6
ENST00000506956.5
ENST00000512671.6
ENST00000345843.8
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr9_-_34397800 0.18 ENST00000297623.7
C9orf24
chromosome 9 open reading frame 24
chr14_-_77320741 0.18 ENST00000682795.1
ENST00000682247.1
POMT2
protein O-mannosyltransferase 2
chr20_+_32358303 0.18 ENST00000651418.1
ENST00000375687.10
ENST00000542461.5
ENST00000613218.4
ENST00000646367.1
ENST00000620121.4
ASXL1
ASXL transcriptional regulator 1
chr6_+_33204645 0.18 ENST00000374662.4
HSD17B8
hydroxysteroid 17-beta dehydrogenase 8
chr11_-_123885627 0.17 ENST00000528595.1
ENST00000375026.7
TMEM225
transmembrane protein 225
chrX_-_153944621 0.17 ENST00000393700.8
RENBP
renin binding protein
chr1_+_44674688 0.17 ENST00000418644.5
ENST00000458657.6
ENST00000535358.6
ENST00000441519.5
ENST00000445071.5
ARMH1
armadillo like helical domain containing 1
chr15_+_82262781 0.16 ENST00000566205.1
ENST00000339465.5
ENST00000569120.1
ENST00000682753.1
ENST00000566861.5
ENST00000565432.1
SAXO2
stabilizer of axonemal microtubules 2
chr12_-_24562438 0.15 ENST00000646273.1
ENST00000659413.1
ENST00000446891.7
SOX5
SRY-box transcription factor 5
chr1_+_110034607 0.15 ENST00000369795.8
STRIP1
striatin interacting protein 1
chrX_+_38561530 0.14 ENST00000378482.7
ENST00000286824.6
TSPAN7
tetraspanin 7
chr2_-_74529670 0.14 ENST00000377526.4
AUP1
AUP1 lipid droplet regulating VLDL assembly factor
chr12_-_53335737 0.13 ENST00000303846.3
SP7
Sp7 transcription factor
chr13_+_21140774 0.13 ENST00000450573.5
ENST00000467636.1
SAP18
Sin3A associated protein 18
chr8_-_80030232 0.13 ENST00000518271.1
ENST00000276585.9
ENST00000521605.1
MRPS28
mitochondrial ribosomal protein S28
chr2_-_38076076 0.13 ENST00000614273.1
ENST00000610745.5
ENST00000490576.1
CYP1B1
cytochrome P450 family 1 subfamily B member 1
chr1_-_29181809 0.12 ENST00000466448.4
ENST00000373795.7
SRSF4
serine and arginine rich splicing factor 4
chr2_+_46698909 0.12 ENST00000650611.1
ENST00000306503.5
LINC01118
SOCS5
long intergenic non-protein coding RNA 1118
suppressor of cytokine signaling 5
chr5_-_88268801 0.12 ENST00000506536.5
ENST00000512429.5
ENST00000514135.5
ENST00000296595.11
ENST00000509387.5
TMEM161B
transmembrane protein 161B
chr11_-_26722051 0.10 ENST00000396005.8
SLC5A12
solute carrier family 5 member 12
chr19_+_11239602 0.10 ENST00000252453.12
ANGPTL8
angiopoietin like 8
chr10_-_121596117 0.10 ENST00000351936.11
FGFR2
fibroblast growth factor receptor 2
chr3_+_150546671 0.10 ENST00000487799.5
EIF2A
eukaryotic translation initiation factor 2A
chr1_-_155911340 0.10 ENST00000368323.8
RIT1
Ras like without CAAX 1
chr15_+_45129933 0.10 ENST00000321429.8
ENST00000389037.7
ENST00000558322.5
DUOX1
dual oxidase 1
chr1_+_40247926 0.09 ENST00000372766.4
TMCO2
transmembrane and coiled-coil domains 2
chr2_-_42361198 0.09 ENST00000234301.3
COX7A2L
cytochrome c oxidase subunit 7A2 like
chr22_+_41381923 0.08 ENST00000266304.9
TEF
TEF transcription factor, PAR bZIP family member
chr14_+_41608344 0.08 ENST00000554120.5
LRFN5
leucine rich repeat and fibronectin type III domain containing 5
chr1_-_982086 0.07 ENST00000341290.6
PERM1
PPARGC1 and ESRR induced regulator, muscle 1
chr1_-_113905020 0.07 ENST00000432415.5
ENST00000369571.2
ENST00000256658.8
ENST00000369564.5
AP4B1
adaptor related protein complex 4 subunit beta 1
chr5_+_79612410 0.07 ENST00000423041.6
ENST00000504233.5
ENST00000453514.6
ENST00000428308.6
TENT2
terminal nucleotidyltransferase 2
chr19_+_43596388 0.06 ENST00000391965.6
ENST00000525771.1
ZNF576
zinc finger protein 576
chr3_+_150546765 0.06 ENST00000406576.7
ENST00000460851.6
ENST00000482093.5
ENST00000273435.9
EIF2A
eukaryotic translation initiation factor 2A
chr1_-_19923617 0.06 ENST00000375116.3
PLA2G2E
phospholipase A2 group IIE
chr7_+_151048526 0.06 ENST00000349064.10
ASIC3
acid sensing ion channel subunit 3
chr5_+_171419635 0.06 ENST00000274625.6
FGF18
fibroblast growth factor 18
chr17_-_41586887 0.06 ENST00000167586.7
KRT14
keratin 14
chr19_-_43198079 0.05 ENST00000597374.5
ENST00000599371.1
PSG4
pregnancy specific beta-1-glycoprotein 4
chrX_-_40177213 0.05 ENST00000672922.2
ENST00000378455.8
ENST00000342274.8
BCOR
BCL6 corepressor
chr22_-_40862070 0.05 ENST00000307221.5
DNAJB7
DnaJ heat shock protein family (Hsp40) member B7
chr1_+_212624472 0.04 ENST00000294829.5
FAM71A
family with sequence similarity 71 member A
chr16_-_4242068 0.04 ENST00000399609.7
SRL
sarcalumenin
chr12_+_109139397 0.04 ENST00000377854.9
ENST00000377848.7
ACACB
acetyl-CoA carboxylase beta
chr1_-_30908681 0.03 ENST00000339394.7
SDC3
syndecan 3
chr14_-_21023954 0.03 ENST00000554094.5
NDRG2
NDRG family member 2
chr17_-_41047267 0.03 ENST00000542137.1
ENST00000391419.3
KRTAP2-1
keratin associated protein 2-1
chr3_+_46497970 0.03 ENST00000296142.4
RTP3
receptor transporter protein 3
chr6_+_10585748 0.03 ENST00000265012.5
GCNT2
glucosaminyl (N-acetyl) transferase 2 (I blood group)
chr6_+_54307856 0.02 ENST00000370869.7
TINAG
tubulointerstitial nephritis antigen
chr22_+_24423597 0.02 ENST00000424232.5
ENST00000611543.4
ENST00000486108.1
ADORA2A
adenosine A2a receptor
chr12_-_118372883 0.02 ENST00000542532.5
ENST00000392533.8
TAOK3
TAO kinase 3
chrX_-_43882411 0.02 ENST00000378069.5
MAOB
monoamine oxidase B
chr14_-_77320855 0.02 ENST00000556394.2
ENST00000261534.9
POMT2
protein O-mannosyltransferase 2
chr14_-_77320813 0.02 ENST00000682467.1
POMT2
protein O-mannosyltransferase 2
chr7_-_143647646 0.00 ENST00000636941.1
TCAF2C
TRPM8 channel associated factor 2C

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 12.5 GO:0001315 age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
1.1 5.3 GO:2000325 regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
0.9 3.5 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.7 5.9 GO:0080009 mRNA methylation(GO:0080009)
0.6 1.9 GO:0006117 acetaldehyde metabolic process(GO:0006117)
0.6 1.7 GO:0070902 mitochondrial tRNA pseudouridine synthesis(GO:0070902)
0.5 2.1 GO:0032581 ER-dependent peroxisome organization(GO:0032581)
0.4 1.2 GO:0071962 mitotic sister chromatid cohesion, centromeric(GO:0071962)
0.4 2.1 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.3 3.4 GO:0071492 cellular response to UV-A(GO:0071492)
0.3 1.0 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.3 1.0 GO:0035565 regulation of pronephros size(GO:0035565)
0.3 1.1 GO:0097325 melanocyte proliferation(GO:0097325)
0.2 0.7 GO:1903572 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.2 0.6 GO:0071338 submandibular salivary gland formation(GO:0060661) hair follicle cell proliferation(GO:0071335) regulation of hair follicle cell proliferation(GO:0071336) positive regulation of hair follicle cell proliferation(GO:0071338)
0.2 0.6 GO:1904383 response to sodium phosphate(GO:1904383)
0.1 1.0 GO:2000035 regulation of stem cell division(GO:2000035)
0.1 0.4 GO:0021763 subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) superior vena cava morphogenesis(GO:0060578)
0.1 0.6 GO:0019556 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.1 0.6 GO:0090131 mesenchyme migration(GO:0090131)
0.1 0.9 GO:0016926 protein desumoylation(GO:0016926)
0.1 0.4 GO:0010902 positive regulation of very-low-density lipoprotein particle remodeling(GO:0010902)
0.1 2.7 GO:0032060 bleb assembly(GO:0032060)
0.1 0.4 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.1 1.4 GO:0051665 membrane raft localization(GO:0051665)
0.1 1.5 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.1 0.3 GO:0036135 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.1 0.8 GO:0071798 response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.1 0.2 GO:1900920 regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920)
0.1 1.9 GO:0035641 locomotory exploration behavior(GO:0035641)
0.1 0.2 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.1 0.6 GO:0042256 mature ribosome assembly(GO:0042256)
0.0 0.4 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.0 0.8 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 0.1 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.0 0.4 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.7 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.0 1.2 GO:0036151 phosphatidylcholine acyl-chain remodeling(GO:0036151)
0.0 1.0 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 0.2 GO:1990928 response to amino acid starvation(GO:1990928)
0.0 0.6 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.9 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 0.6 GO:0042994 cytoplasmic sequestering of transcription factor(GO:0042994)
0.0 0.2 GO:1904098 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.0 0.1 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0 0.5 GO:0070445 oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.0 0.2 GO:0006051 mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
0.0 0.2 GO:1905068 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 0.2 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 0.1 GO:0042335 cuticle development(GO:0042335)
0.0 0.6 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 1.0 GO:0050869 negative regulation of B cell activation(GO:0050869)
0.0 0.2 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 0.1 GO:0035602 fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604) fibroblast growth factor receptor signaling pathway involved in mammary gland specification(GO:0060595) mammary gland bud formation(GO:0060615) branch elongation involved in salivary gland morphogenesis(GO:0060667) mesenchymal cell differentiation involved in lung development(GO:0060915)
0.0 0.3 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.0 0.4 GO:0008655 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0 0.3 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.0 0.2 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.0 0.5 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.4 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.6 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.0 0.1 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.0 0.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.1 GO:0050915 iron chelate transport(GO:0015688) siderophore transport(GO:0015891) sensory perception of sour taste(GO:0050915)
0.0 1.1 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 5.9 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.6 1.9 GO:0035525 NF-kappaB p50/p65 complex(GO:0035525)
0.4 5.3 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.3 1.0 GO:0018444 translation release factor complex(GO:0018444)
0.2 3.5 GO:0035631 CD40 receptor complex(GO:0035631)
0.2 1.2 GO:0031415 NatA complex(GO:0031415)
0.1 0.5 GO:0072534 perineuronal net(GO:0072534)
0.1 1.1 GO:0071438 invadopodium membrane(GO:0071438)
0.1 2.1 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1 1.0 GO:0017119 Golgi transport complex(GO:0017119)
0.1 0.4 GO:0032280 symmetric synapse(GO:0032280)
0.0 0.7 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.2 GO:0035517 PR-DUB complex(GO:0035517)
0.0 0.3 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.0 0.6 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.3 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.1 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.2 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.4 GO:0045179 apical cortex(GO:0045179)
0.0 0.3 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.8 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.9 GO:0071565 nBAF complex(GO:0071565)
0.0 0.2 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 14.3 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.2 GO:0031931 TORC1 complex(GO:0031931)
0.0 2.1 GO:0005811 lipid particle(GO:0005811)
0.0 3.2 GO:0005903 brush border(GO:0005903)
0.0 0.8 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.4 GO:0042627 chylomicron(GO:0042627)
0.0 0.2 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.7 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.3 GO:0044295 axonal growth cone(GO:0044295)
0.0 1.9 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.2 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 12.5 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.6 1.7 GO:0004730 pseudouridylate synthase activity(GO:0004730)
0.5 1.4 GO:0031755 endothelial differentiation G-protein coupled receptor binding(GO:0031753) Edg-2 lysophosphatidic acid receptor binding(GO:0031755)
0.4 1.2 GO:0052858 peptidyl-lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0052858)
0.3 0.8 GO:0030156 benzodiazepine receptor binding(GO:0030156)
0.3 0.8 GO:0004958 prostaglandin F receptor activity(GO:0004958)
0.2 1.9 GO:0071532 ankyrin repeat binding(GO:0071532)
0.2 0.9 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.2 0.6 GO:0032427 GBD domain binding(GO:0032427)
0.1 0.7 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 0.4 GO:0009032 thymidine phosphorylase activity(GO:0009032) pyrimidine-nucleoside phosphorylase activity(GO:0016154)
0.1 1.0 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1 0.5 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.1 5.4 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 0.4 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.1 0.7 GO:0004969 histamine receptor activity(GO:0004969)
0.1 1.4 GO:0048185 activin binding(GO:0048185)
0.1 0.4 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1 0.4 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.1 0.2 GO:0047025 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
0.1 0.7 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.6 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 1.1 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.3 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.5 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.8 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.2 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 1.6 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.6 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.9 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.3 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.2 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 4.0 GO:0008238 exopeptidase activity(GO:0008238)
0.0 4.3 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.2 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.0 0.6 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 1.0 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.2 GO:1990239 steroid hormone binding(GO:1990239)
0.0 0.8 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.5 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.1 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0 0.5 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.3 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.1 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 0.2 GO:0000150 recombinase activity(GO:0000150)
0.0 0.4 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.1 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 0.1 GO:1990825 sequence-specific mRNA binding(GO:1990825)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 13.9 PID FOXO PATHWAY FoxO family signaling
0.1 1.9 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.7 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.6 ST GAQ PATHWAY G alpha q Pathway
0.0 1.8 SIG CHEMOTAXIS Genes related to chemotaxis
0.0 0.9 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.9 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.3 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.6 PID RHOA PATHWAY RhoA signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.1 0.8 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.1 1.4 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.7 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.9 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.6 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.4 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.4 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.4 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.4 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.3 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 1.0 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.6 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.5 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.2 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.5 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions