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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for NR2E1

Z-value: 0.74

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Transcription factors associated with NR2E1

Gene Symbol Gene ID Gene Info
NR2E1
ENSG00000112333.12 NR2E1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR2E1hg38_v1_chr6_+_108166015_1081660340.321.2e-01Click!

Activity profile of NR2E1 motif

Sorted Z-values of NR2E1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of NR2E1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr1_-_169734064 3.01 ENST00000333360.12
SELE
selectin E
chr3_-_64687613 1.95 ENST00000295903.8
ADAMTS9
ADAM metallopeptidase with thrombospondin type 1 motif 9
chr3_-_64687992 1.83 ENST00000498707.5
ADAMTS9
ADAM metallopeptidase with thrombospondin type 1 motif 9
chr9_-_16728165 1.76 ENST00000603713.5
ENST00000603313.5
BNC2
basonuclin 2
chr16_+_57620077 1.57 ENST00000567835.5
ENST00000569372.5
ENST00000563548.5
ENST00000562003.5
ADGRG1
adhesion G protein-coupled receptor G1
chr11_-_8810635 1.49 ENST00000527510.5
ENST00000528527.5
ENST00000313726.11
ENST00000528523.5
DENND2B
DENN domain containing 2B
chr15_+_67067780 1.34 ENST00000679624.1
SMAD3
SMAD family member 3
chr17_-_43546323 1.21 ENST00000545954.5
ENST00000319349.10
ETV4
ETS variant transcription factor 4
chr8_+_103372388 1.19 ENST00000520337.1
CTHRC1
collagen triple helix repeat containing 1
chr4_-_121164314 1.19 ENST00000057513.8
TNIP3
TNFAIP3 interacting protein 3
chr12_+_55681647 1.03 ENST00000614691.1
METTL7B
methyltransferase like 7B
chr12_+_55681711 1.01 ENST00000394252.4
METTL7B
methyltransferase like 7B
chr4_+_95091462 1.00 ENST00000264568.8
BMPR1B
bone morphogenetic protein receptor type 1B
chr1_+_212565334 1.00 ENST00000366981.8
ENST00000366987.6
ATF3
activating transcription factor 3
chr11_+_35176611 0.99 ENST00000279452.10
CD44
CD44 molecule (Indian blood group)
chr12_+_63844758 0.98 ENST00000631006.2
SRGAP1
SLIT-ROBO Rho GTPase activating protein 1
chr11_+_35176696 0.94 ENST00000528455.5
CD44
CD44 molecule (Indian blood group)
chr20_+_54475647 0.93 ENST00000395939.5
DOK5
docking protein 5
chr11_+_35176639 0.91 ENST00000527889.6
CD44
CD44 molecule (Indian blood group)
chr2_+_230759918 0.90 ENST00000614925.1
CAB39
calcium binding protein 39
chr11_-_128587551 0.90 ENST00000392668.8
ETS1
ETS proto-oncogene 1, transcription factor
chr11_+_35176575 0.89 ENST00000526000.6
CD44
CD44 molecule (Indian blood group)
chr6_+_31948956 0.89 ENST00000483004.1
CFB
complement factor B
chr1_+_165895564 0.77 ENST00000469256.6
UCK2
uridine-cytidine kinase 2
chr20_+_63738270 0.76 ENST00000467211.1
ENSG00000273047.1
novel transcript, LIME1-SLC2A4RG readthrough
chr8_-_118111806 0.75 ENST00000378204.7
EXT1
exostosin glycosyltransferase 1
chr12_+_63844663 0.74 ENST00000355086.8
SRGAP1
SLIT-ROBO Rho GTPase activating protein 1
chr2_-_207165923 0.72 ENST00000309446.11
KLF7
Kruppel like factor 7
chr19_+_13023958 0.70 ENST00000587760.5
ENST00000585575.5
NFIX
nuclear factor I X
chr9_-_96302142 0.69 ENST00000648799.1
HSD17B3
hydroxysteroid 17-beta dehydrogenase 3
chr2_-_231125032 0.68 ENST00000258400.4
HTR2B
5-hydroxytryptamine receptor 2B
chr5_-_59216826 0.66 ENST00000638939.1
PDE4D
phosphodiesterase 4D
chr7_-_13986439 0.66 ENST00000443608.5
ENST00000438956.5
ETV1
ETS variant transcription factor 1
chr1_+_158461574 0.62 ENST00000641432.1
ENST00000641460.1
ENST00000641535.1
ENST00000641971.1
OR10K1
olfactory receptor family 10 subfamily K member 1
chr7_-_108240049 0.61 ENST00000379022.8
NRCAM
neuronal cell adhesion molecule
chr17_-_42681840 0.58 ENST00000332438.4
CCR10
C-C motif chemokine receptor 10
chr3_-_71132099 0.57 ENST00000650188.1
ENST00000648121.1
ENST00000648794.1
ENST00000649592.1
FOXP1
forkhead box P1
chr17_-_3691887 0.56 ENST00000552050.5
P2RX5
purinergic receptor P2X 5
chr18_+_80109236 0.56 ENST00000262198.9
ENST00000560752.5
ADNP2
ADNP homeobox 2
chr16_-_66918839 0.55 ENST00000565235.2
ENST00000568632.5
ENST00000565796.5
CDH16
cadherin 16
chr12_+_111034136 0.54 ENST00000261726.11
CUX2
cut like homeobox 2
chr16_-_66918876 0.54 ENST00000570262.5
ENST00000299752.9
ENST00000394055.7
CDH16
cadherin 16
chr12_-_55842950 0.54 ENST00000548629.5
MMP19
matrix metallopeptidase 19
chr3_+_101827982 0.53 ENST00000461724.5
ENST00000483180.5
ENST00000394054.6
NFKBIZ
NFKB inhibitor zeta
chr5_-_161546671 0.52 ENST00000517547.5
GABRB2
gamma-aminobutyric acid type A receptor subunit beta2
chr19_-_46717076 0.52 ENST00000601806.5
ENST00000593363.1
ENST00000291281.9
ENST00000598633.1
ENST00000595515.5
ENST00000433867.5
PRKD2
protein kinase D2
chr14_-_34874887 0.52 ENST00000382422.6
BAZ1A
bromodomain adjacent to zinc finger domain 1A
chr4_-_156970903 0.52 ENST00000422544.2
PDGFC
platelet derived growth factor C
chr1_+_147902789 0.51 ENST00000369235.2
GJA8
gap junction protein alpha 8
chr6_+_131199979 0.51 ENST00000537868.5
AKAP7
A-kinase anchoring protein 7
chr12_+_26195313 0.51 ENST00000422622.3
SSPN
sarcospan
chr6_+_158649997 0.51 ENST00000360448.8
ENST00000367081.7
ENST00000611299.5
SYTL3
synaptotagmin like 3
chr5_-_161546970 0.50 ENST00000675303.1
GABRB2
gamma-aminobutyric acid type A receptor subunit beta2
chr19_+_13024573 0.50 ENST00000358552.7
ENST00000360105.8
ENST00000588228.5
ENST00000676441.1
ENST00000591028.1
NFIX
nuclear factor I X
chr1_+_170664121 0.50 ENST00000239461.11
PRRX1
paired related homeobox 1
chr21_-_34888683 0.49 ENST00000344691.8
ENST00000358356.9
RUNX1
RUNX family transcription factor 1
chr5_-_160852200 0.49 ENST00000327245.10
ATP10B
ATPase phospholipid transporting 10B (putative)
chr11_-_63671909 0.47 ENST00000538786.1
ENST00000540699.1
ATL3
atlastin GTPase 3
chr5_-_33891941 0.47 ENST00000352040.7
ENST00000504830.6
ADAMTS12
ADAM metallopeptidase with thrombospondin type 1 motif 12
chr1_-_158426237 0.47 ENST00000641042.1
OR10K2
olfactory receptor family 10 subfamily K member 2
chr20_-_31722533 0.46 ENST00000677194.1
ENST00000434194.2
ENST00000376062.6
BCL2L1
BCL2 like 1
chrX_-_66040072 0.46 ENST00000374737.9
VSIG4
V-set and immunoglobulin domain containing 4
chr1_+_89821003 0.45 ENST00000525774.5
ENST00000337338.9
LRRC8D
leucine rich repeat containing 8 VRAC subunit D
chr20_+_44531817 0.45 ENST00000372889.5
ENST00000372887.5
PKIG
cAMP-dependent protein kinase inhibitor gamma
chr17_+_75979211 0.45 ENST00000397640.6
ENST00000588202.5
ENST00000590676.1
ENST00000586891.1
TEN1
TEN1 subunit of CST complex
chr11_+_31812307 0.45 ENST00000643436.1
ENST00000646959.1
ENST00000645942.1
ENST00000530348.5
PAUPAR
ENSG00000285283.1
PAX6 upstream antisense RNA
novel protein
chr5_-_179620933 0.44 ENST00000521173.5
HNRNPH1
heterogeneous nuclear ribonucleoprotein H1
chrX_-_66040057 0.44 ENST00000412866.2
VSIG4
V-set and immunoglobulin domain containing 4
chr5_-_143400716 0.43 ENST00000424646.6
ENST00000652686.1
NR3C1
nuclear receptor subfamily 3 group C member 1
chr19_-_633500 0.43 ENST00000588649.7
POLRMT
RNA polymerase mitochondrial
chr17_-_8087709 0.42 ENST00000647874.1
ALOX12B
arachidonate 12-lipoxygenase, 12R type
chrX_-_49184789 0.42 ENST00000453382.5
ENST00000432913.5
PRICKLE3
prickle planar cell polarity protein 3
chr7_-_106285898 0.42 ENST00000424768.2
ENST00000681255.1
NAMPT
nicotinamide phosphoribosyltransferase
chrX_-_66040107 0.42 ENST00000455586.6
VSIG4
V-set and immunoglobulin domain containing 4
chr7_+_116526277 0.42 ENST00000393468.1
ENST00000393467.1
CAV1
caveolin 1
chr3_+_122055355 0.41 ENST00000330540.7
ENST00000469710.5
ENST00000493101.5
CD86
CD86 molecule
chr4_-_122621011 0.41 ENST00000611104.2
ENST00000648588.1
IL21
interleukin 21
chr10_+_5692792 0.41 ENST00000645567.1
TASOR2
transcription activation suppressor family member 2
chr4_-_47981535 0.41 ENST00000402813.9
CNGA1
cyclic nucleotide gated channel subunit alpha 1
chr14_+_51489112 0.41 ENST00000356218.8
FRMD6
FERM domain containing 6
chr12_+_26195647 0.40 ENST00000535504.1
SSPN
sarcospan
chr14_-_34875348 0.40 ENST00000360310.6
BAZ1A
bromodomain adjacent to zinc finger domain 1A
chr16_-_69754913 0.40 ENST00000268802.10
NOB1
NIN1 (RPN12) binding protein 1 homolog
chr12_-_99154867 0.39 ENST00000549025.6
ANKS1B
ankyrin repeat and sterile alpha motif domain containing 1B
chr6_-_160664270 0.39 ENST00000316300.10
LPA
lipoprotein(a)
chr12_-_81758641 0.39 ENST00000552948.5
ENST00000548586.5
PPFIA2
PTPRF interacting protein alpha 2
chr4_+_80266639 0.39 ENST00000456523.3
ENST00000312465.12
FGF5
fibroblast growth factor 5
chr6_+_106098933 0.39 ENST00000369089.3
PRDM1
PR/SET domain 1
chr19_+_9087061 0.39 ENST00000641627.1
OR1M1
olfactory receptor family 1 subfamily M member 1
chr8_-_121641424 0.39 ENST00000303924.5
HAS2
hyaluronan synthase 2
chr10_+_84230660 0.39 ENST00000652073.1
RGR
retinal G protein coupled receptor
chr3_+_128052390 0.38 ENST00000481210.5
ENST00000243253.8
SEC61A1
SEC61 translocon subunit alpha 1
chrX_+_137566119 0.38 ENST00000287538.10
ZIC3
Zic family member 3
chr12_+_26195543 0.38 ENST00000242729.7
SSPN
sarcospan
chr6_-_42722590 0.38 ENST00000230381.7
PRPH2
peripherin 2
chr1_+_39955112 0.37 ENST00000420632.6
ENST00000372811.10
ENST00000434861.5
ENST00000372809.5
MFSD2A
major facilitator superfamily domain containing 2A
chr20_-_31722854 0.37 ENST00000307677.5
BCL2L1
BCL2 like 1
chrX_-_115018973 0.37 ENST00000371936.5
IL13RA2
interleukin 13 receptor subunit alpha 2
chr5_-_9546066 0.36 ENST00000382496.10
ENST00000652226.1
SEMA5A
semaphorin 5A
chr1_+_150257247 0.35 ENST00000647854.1
CA14
carbonic anhydrase 14
chr17_+_17179527 0.35 ENST00000579361.1
MPRIP
myosin phosphatase Rho interacting protein
chr1_+_150257764 0.35 ENST00000369111.9
CA14
carbonic anhydrase 14
chr12_+_53268289 0.35 ENST00000257934.9
ESPL1
extra spindle pole bodies like 1, separase
chr3_-_157503574 0.35 ENST00000494677.5
ENST00000468233.5
VEPH1
ventricular zone expressed PH domain containing 1
chr3_-_71583683 0.34 ENST00000649631.1
ENST00000648718.1
FOXP1
forkhead box P1
chr5_-_161546708 0.34 ENST00000393959.6
GABRB2
gamma-aminobutyric acid type A receptor subunit beta2
chr1_+_67685342 0.33 ENST00000617962.2
GADD45A
growth arrest and DNA damage inducible alpha
chr3_-_116445458 0.33 ENST00000490035.7
LSAMP
limbic system associated membrane protein
chr5_-_16936231 0.33 ENST00000507288.1
ENST00000274203.13
ENST00000513610.6
MYO10
myosin X
chr6_+_45422564 0.32 ENST00000625924.1
RUNX2
RUNX family transcription factor 2
chrX_-_53684119 0.32 ENST00000342160.7
ENST00000446750.1
HUWE1
HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1
chr3_+_12351493 0.32 ENST00000683699.1
PPARG
peroxisome proliferator activated receptor gamma
chr9_-_21994345 0.31 ENST00000579755.2
ENST00000530628.2
CDKN2A
cyclin dependent kinase inhibitor 2A
chr16_+_7304219 0.31 ENST00000675562.1
RBFOX1
RNA binding fox-1 homolog 1
chr12_-_99154492 0.31 ENST00000546568.5
ENST00000546960.5
ANKS1B
ankyrin repeat and sterile alpha motif domain containing 1B
chr14_-_56810448 0.30 ENST00000339475.10
ENST00000555006.5
ENST00000672264.2
ENST00000554559.5
ENST00000555804.1
OTX2
orthodenticle homeobox 2
chr17_-_8295342 0.30 ENST00000579192.5
ENST00000577745.2
SLC25A35
solute carrier family 25 member 35
chr17_-_31297231 0.30 ENST00000247271.5
OMG
oligodendrocyte myelin glycoprotein
chr14_+_36661852 0.30 ENST00000361487.7
PAX9
paired box 9
chr12_-_55842927 0.30 ENST00000322569.9
ENST00000409200.7
MMP19
matrix metallopeptidase 19
chr6_+_42564060 0.30 ENST00000372903.6
UBR2
ubiquitin protein ligase E3 component n-recognin 2
chr12_-_99154746 0.30 ENST00000549558.6
ENST00000550693.6
ENST00000549493.6
ANKS1B
ankyrin repeat and sterile alpha motif domain containing 1B
chr1_+_170663917 0.29 ENST00000497230.2
PRRX1
paired related homeobox 1
chr6_+_13013513 0.29 ENST00000675203.1
PHACTR1
phosphatase and actin regulator 1
chr18_+_74597850 0.29 ENST00000582337.5
ENST00000299687.10
ZNF407
zinc finger protein 407
chr5_+_177600104 0.29 ENST00000029410.10
ENST00000510761.1
ENST00000505468.1
B4GALT7
beta-1,4-galactosyltransferase 7
chr6_+_45422485 0.28 ENST00000359524.7
RUNX2
RUNX family transcription factor 2
chr17_-_75262344 0.28 ENST00000579743.2
ENST00000578348.5
ENST00000582486.5
ENST00000582717.5
GGA3
golgi associated, gamma adaptin ear containing, ARF binding protein 3
chr7_-_51316754 0.28 ENST00000632460.1
ENST00000441453.5
ENST00000648294.1
ENST00000265136.12
ENST00000395542.6
ENST00000395540.6
COBL
cordon-bleu WH2 repeat protein
chr1_-_94927079 0.28 ENST00000370206.9
ENST00000394202.8
CNN3
calponin 3
chr9_-_111330224 0.28 ENST00000302681.3
OR2K2
olfactory receptor family 2 subfamily K member 2
chr4_+_87650277 0.28 ENST00000339673.11
ENST00000282479.8
DMP1
dentin matrix acidic phosphoprotein 1
chr9_-_92482350 0.27 ENST00000375543.2
ASPN
asporin
chr5_+_32711723 0.27 ENST00000415167.2
NPR3
natriuretic peptide receptor 3
chr20_+_18813777 0.27 ENST00000377428.4
SCP2D1
SCP2 sterol binding domain containing 1
chr17_-_75393656 0.27 ENST00000392563.5
GRB2
growth factor receptor bound protein 2
chr1_+_110873135 0.27 ENST00000271324.6
CD53
CD53 molecule
chr14_+_22508602 0.26 ENST00000390504.1
TRAJ33
T cell receptor alpha joining 33
chr17_-_676348 0.26 ENST00000681510.1
ENST00000679680.1
VPS53
VPS53 subunit of GARP complex
chr11_-_5269933 0.26 ENST00000396895.3
HBE1
hemoglobin subunit epsilon 1
chr17_+_2056073 0.26 ENST00000576444.1
ENST00000322941.3
HIC1
HIC ZBTB transcriptional repressor 1
chr3_-_71583592 0.26 ENST00000650156.1
ENST00000649596.1
FOXP1
forkhead box P1
chr5_+_119629552 0.26 ENST00000613773.4
ENST00000620555.4
ENST00000515256.5
ENST00000509264.1
FAM170A
family with sequence similarity 170 member A
chr3_-_116444983 0.26 ENST00000333617.8
LSAMP
limbic system associated membrane protein
chr8_+_85209213 0.25 ENST00000520225.1
E2F5
E2F transcription factor 5
chr20_-_31722949 0.25 ENST00000376055.9
BCL2L1
BCL2 like 1
chr16_-_3018170 0.25 ENST00000572154.1
ENST00000328796.5
CLDN6
claudin 6
chr19_+_58544045 0.25 ENST00000253024.10
ENST00000593582.5
TRIM28
tripartite motif containing 28
chr1_-_243850216 0.24 ENST00000673466.1
AKT3
AKT serine/threonine kinase 3
chr17_-_75393741 0.24 ENST00000578961.5
ENST00000392564.5
GRB2
growth factor receptor bound protein 2
chr1_+_213989691 0.24 ENST00000607425.1
PROX1
prospero homeobox 1
chr1_+_152878312 0.24 ENST00000368765.4
SMCP
sperm mitochondria associated cysteine rich protein
chr18_+_34710307 0.23 ENST00000679796.1
DTNA
dystrobrevin alpha
chr17_+_42609641 0.23 ENST00000681413.1
ENST00000251413.8
ENST00000591509.5
TUBG1
tubulin gamma 1
chr16_+_30664334 0.23 ENST00000287468.5
FBRS
fibrosin
chr5_+_137867852 0.23 ENST00000421631.6
ENST00000239926.9
MYOT
myotilin
chr17_-_28368012 0.23 ENST00000555059.2
ENSG00000273171.1
novel protein, readthrough between VTN and SEBOX
chr1_-_115768702 0.23 ENST00000261448.6
CASQ2
calsequestrin 2
chr4_-_108168950 0.23 ENST00000379951.6
LEF1
lymphoid enhancer binding factor 1
chr8_-_673547 0.23 ENST00000522893.1
ERICH1
glutamate rich 1
chr4_-_40630588 0.23 ENST00000514014.1
RBM47
RNA binding motif protein 47
chr4_-_108168919 0.23 ENST00000265165.6
LEF1
lymphoid enhancer binding factor 1
chrX_+_47218670 0.23 ENST00000357227.9
ENST00000519758.5
ENST00000520893.5
ENST00000622098.4
ENST00000517426.5
CDK16
cyclin dependent kinase 16
chr7_+_123601815 0.23 ENST00000451215.6
ASB15
ankyrin repeat and SOCS box containing 15
chr17_+_7630094 0.22 ENST00000441599.6
ENST00000380450.9
ENST00000416273.7
ENST00000575903.5
ENST00000571153.5
ENST00000575618.5
ENST00000576152.1
ENST00000576830.5
SHBG
sex hormone binding globulin
chr5_-_102296260 0.22 ENST00000310954.7
SLCO4C1
solute carrier organic anion transporter family member 4C1
chr22_-_30299482 0.22 ENST00000434291.5
ENSG00000248751.6
novel protein
chr5_+_32711313 0.22 ENST00000265074.13
NPR3
natriuretic peptide receptor 3
chrX_+_47218232 0.22 ENST00000457458.6
ENST00000522883.1
CDK16
cyclin dependent kinase 16
chr12_-_119803383 0.21 ENST00000392520.2
ENST00000678677.1
ENST00000679249.1
ENST00000676849.1
CIT
citron rho-interacting serine/threonine kinase
chrX_+_136532205 0.21 ENST00000370634.8
VGLL1
vestigial like family member 1
chr7_+_123601836 0.21 ENST00000434204.5
ASB15
ankyrin repeat and SOCS box containing 15
chr6_-_138499487 0.21 ENST00000343505.9
NHSL1
NHS like 1
chr7_+_114414997 0.21 ENST00000462331.5
ENST00000393491.7
ENST00000403559.8
ENST00000408937.7
ENST00000393498.6
ENST00000393495.7
ENST00000378237.7
FOXP2
forkhead box P2
chr3_+_138621225 0.21 ENST00000479848.1
FAIM
Fas apoptotic inhibitory molecule
chr16_+_21678514 0.21 ENST00000286149.8
ENST00000388958.8
OTOA
otoancorin
chr6_-_130222813 0.20 ENST00000437477.6
ENST00000439090.7
SAMD3
sterile alpha motif domain containing 3
chr11_-_31807617 0.20 ENST00000639920.1
ENST00000640460.1
PAX6
paired box 6
chr14_+_22168387 0.20 ENST00000557168.1
TRAV30
T cell receptor alpha variable 30
chr3_+_189631373 0.20 ENST00000264731.8
ENST00000418709.6
ENST00000320472.9
ENST00000392460.7
ENST00000440651.6
TP63
tumor protein p63
chr14_-_56810380 0.20 ENST00000672125.1
ENST00000673481.1
OTX2
orthodenticle homeobox 2
chr16_+_30075967 0.20 ENST00000279387.12
ENST00000562664.5
ENST00000627746.2
ENST00000562222.5
PPP4C
protein phosphatase 4 catalytic subunit
chr3_-_51499950 0.19 ENST00000423656.5
ENST00000504652.5
ENST00000684031.1
DCAF1
DDB1 and CUL4 associated factor 1
chr6_-_87702221 0.19 ENST00000257787.6
AKIRIN2
akirin 2
chr10_-_59753444 0.19 ENST00000594536.5
ENST00000414264.6
MRLN
myoregulin
chr7_-_107803215 0.19 ENST00000340010.10
ENST00000453332.1
SLC26A3
solute carrier family 26 member 3
chr8_-_115492221 0.19 ENST00000518018.1
TRPS1
transcriptional repressor GATA binding 1
chr17_+_45061296 0.19 ENST00000590310.2
ENST00000677949.1
ENST00000258960.7
NMT1
N-myristoyltransferase 1
chr6_+_31547560 0.19 ENST00000376148.9
ENST00000376145.8
NFKBIL1
NFKB inhibitor like 1
chrX_-_153971169 0.19 ENST00000369984.4
HCFC1
host cell factor C1
chr22_-_41446777 0.19 ENST00000434408.1
ENST00000327492.4
TOB2
transducer of ERBB2, 2
chr10_-_24721866 0.18 ENST00000416305.1
ENST00000320481.10
ARHGAP21
Rho GTPase activating protein 21
chr3_-_197183806 0.18 ENST00000671246.1
ENST00000660553.1
DLG1
discs large MAGUK scaffold protein 1
chr8_+_79611036 0.18 ENST00000220876.12
ENST00000518111.5
STMN2
stathmin 2
chr8_+_76681208 0.18 ENST00000651372.2
ZFHX4
zinc finger homeobox 4
chrX_-_124963768 0.18 ENST00000371130.7
ENST00000422452.2
TENM1
teneurin transmembrane protein 1
chr10_-_72088972 0.18 ENST00000317376.8
ENST00000412663.5
SPOCK2
SPARC (osteonectin), cwcv and kazal like domains proteoglycan 2
chr11_-_70717994 0.18 ENST00000659264.1
SHANK2
SH3 and multiple ankyrin repeat domains 2
chr10_+_84173793 0.18 ENST00000372126.4
C10orf99
chromosome 10 open reading frame 99
chr12_+_80716906 0.18 ENST00000228644.4
MYF5
myogenic factor 5

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.3 4.1 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.2 3.8 GO:0045636 positive regulation of melanocyte differentiation(GO:0045636)
0.2 0.9 GO:2000681 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.2 1.3 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.2 0.8 GO:0046035 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.2 1.2 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.2 1.0 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.1 1.0 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) negative regulation of chondrocyte proliferation(GO:1902731)
0.1 0.4 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.1 0.4 GO:0002665 negative regulation of T cell tolerance induction(GO:0002665) negative regulation of T cell anergy(GO:0002668) negative regulation of lymphocyte anergy(GO:0002912) regulation of lymphotoxin A production(GO:0032681) positive regulation of lymphotoxin A production(GO:0032761) regulation of lymphotoxin A biosynthetic process(GO:0043016) positive regulation of lymphotoxin A biosynthetic process(GO:0043017)
0.1 1.1 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.1 0.7 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.1 0.4 GO:1990654 regulation of extrathymic T cell differentiation(GO:0033082) sebum secreting cell proliferation(GO:1990654)
0.1 2.3 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 0.4 GO:1900085 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.1 3.9 GO:0061756 leukocyte adhesion to vascular endothelial cell(GO:0061756)
0.1 1.6 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.1 0.5 GO:1902202 proteoglycan catabolic process(GO:0030167) regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.1 0.8 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 0.5 GO:0061152 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.1 0.4 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.1 0.8 GO:0001554 luteolysis(GO:0001554)
0.1 0.4 GO:0003383 apical constriction(GO:0003383)
0.1 0.2 GO:0043049 hepatocyte cell migration(GO:0002194) otic placode formation(GO:0043049) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.1 0.3 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.1 0.3 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 0.2 GO:0021757 caudate nucleus development(GO:0021757) putamen development(GO:0021758)
0.1 0.3 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.1 0.6 GO:0002051 osteoblast fate commitment(GO:0002051)
0.1 0.7 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1 0.4 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.1 0.2 GO:1990164 histone H2A phosphorylation(GO:1990164)
0.1 0.4 GO:0039019 pronephric nephron development(GO:0039019)
0.1 0.3 GO:1902080 regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
0.1 0.2 GO:0019046 release from viral latency(GO:0019046)
0.1 1.1 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.1 0.2 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
0.1 0.5 GO:0089700 protein kinase D signaling(GO:0089700)
0.1 0.2 GO:0001897 cytolysis by symbiont of host cells(GO:0001897)
0.1 1.0 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.1 0.8 GO:0048664 neuron fate determination(GO:0048664)
0.1 0.3 GO:0001757 somite specification(GO:0001757)
0.1 0.1 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.1 0.4 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.1 1.4 GO:0071420 cellular response to histamine(GO:0071420)
0.1 0.2 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.0 0.2 GO:1901536 positive regulation of methylation-dependent chromatin silencing(GO:0090309) regulation of DNA demethylation(GO:1901535) negative regulation of DNA demethylation(GO:1901536) regulation of genetic imprinting(GO:2000653)
0.0 0.2 GO:0018008 N-terminal peptidyl-glycine N-myristoylation(GO:0018008)
0.0 0.4 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.0 0.4 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 1.5 GO:0043586 tongue development(GO:0043586)
0.0 0.1 GO:1903033 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.0 0.4 GO:0048842 positive regulation of axon extension involved in axon guidance(GO:0048842)
0.0 0.5 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.6 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.2 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 0.3 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.2 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 0.2 GO:0007341 penetration of zona pellucida(GO:0007341)
0.0 0.3 GO:2000230 negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.0 0.5 GO:0002158 osteoclast proliferation(GO:0002158)
0.0 0.1 GO:2000863 negative regulation of macrophage chemotaxis(GO:0010760) positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.0 0.4 GO:0043305 negative regulation of mast cell degranulation(GO:0043305)
0.0 0.1 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.0 0.1 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.2 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.3 GO:0070170 regulation of tooth mineralization(GO:0070170)
0.0 0.3 GO:0035986 senescence-associated heterochromatin focus assembly(GO:0035986)
0.0 0.5 GO:2000543 positive regulation of gastrulation(GO:2000543)
0.0 0.2 GO:0086029 Purkinje myocyte to ventricular cardiac muscle cell signaling(GO:0086029) Purkinje myocyte to ventricular cardiac muscle cell communication(GO:0086068)
0.0 0.1 GO:0061055 myotome development(GO:0061055)
0.0 0.3 GO:0035989 tendon development(GO:0035989)
0.0 0.1 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634) negative regulation of endothelial cell chemotaxis(GO:2001027)
0.0 0.1 GO:0072268 pattern specification involved in metanephros development(GO:0072268)
0.0 0.6 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0 0.1 GO:0035054 atrial septum secundum morphogenesis(GO:0003290) embryonic heart tube anterior/posterior pattern specification(GO:0035054)
0.0 0.1 GO:0021847 ventricular zone neuroblast division(GO:0021847)
0.0 0.1 GO:1904732 regulation of electron carrier activity(GO:1904732)
0.0 0.2 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 1.1 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.2 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.1 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.4 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.5 GO:0007614 short-term memory(GO:0007614)
0.0 0.2 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.0 0.1 GO:0040030 regulation of molecular function, epigenetic(GO:0040030) positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.0 0.1 GO:0032416 negative regulation of sodium:proton antiporter activity(GO:0032416) musculoskeletal movement, spinal reflex action(GO:0050883)
0.0 0.2 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.0 0.4 GO:0023019 signal transduction involved in regulation of gene expression(GO:0023019)
0.0 0.4 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.4 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.1 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 0.3 GO:0042481 regulation of odontogenesis(GO:0042481)
0.0 0.1 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.0 0.1 GO:0046116 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.0 0.1 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.0 0.4 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.0 0.1 GO:0001807 type IV hypersensitivity(GO:0001806) regulation of type IV hypersensitivity(GO:0001807) negative regulation of type IV hypersensitivity(GO:0001808)
0.0 0.5 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0 0.2 GO:0045852 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.0 0.5 GO:0035641 locomotory exploration behavior(GO:0035641)
0.0 0.4 GO:0060856 establishment of blood-brain barrier(GO:0060856)
0.0 0.1 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.0 0.1 GO:0007060 male meiosis chromosome segregation(GO:0007060)
0.0 0.6 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.0 0.3 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.5 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.4 GO:0000469 cleavage involved in rRNA processing(GO:0000469)
0.0 0.3 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.1 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.3 GO:0034374 low-density lipoprotein particle remodeling(GO:0034374)
0.0 0.1 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 0.2 GO:0000212 meiotic spindle organization(GO:0000212)
0.0 0.2 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0 0.1 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.0 0.2 GO:0003322 pancreatic A cell development(GO:0003322)
0.0 0.1 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.1 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.0 0.1 GO:0071350 interleukin-15-mediated signaling pathway(GO:0035723) cellular response to interleukin-15(GO:0071350)
0.0 0.3 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.4 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0 0.5 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.6 GO:0034142 toll-like receptor 4 signaling pathway(GO:0034142)
0.0 0.3 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.0 0.2 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.3 GO:0015671 oxygen transport(GO:0015671)
0.0 0.2 GO:1903764 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760) regulation of potassium ion export across plasma membrane(GO:1903764)
0.0 0.1 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.4 GO:0032211 negative regulation of telomere maintenance via telomerase(GO:0032211)
0.0 0.7 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.3 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.0 0.1 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.1 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.2 GO:1900103 positive regulation of endoplasmic reticulum unfolded protein response(GO:1900103)
0.0 0.1 GO:2000402 negative regulation of lymphocyte migration(GO:2000402)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.7 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.3 1.0 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.3 0.9 GO:0008623 CHRAC(GO:0008623)
0.2 1.6 GO:0097451 glial limiting end-foot(GO:0097451)
0.1 1.3 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 0.4 GO:1990879 CST complex(GO:1990879)
0.1 0.3 GO:0005592 collagen type XI trimer(GO:0005592)
0.1 1.1 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 0.5 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.1 1.0 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.2 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.0 0.2 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.0 0.4 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.3 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.3 GO:1990745 EARP complex(GO:1990745)
0.0 1.4 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.3 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.2 GO:0005827 polar microtubule(GO:0005827)
0.0 0.1 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.0 0.5 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 3.3 GO:0005901 caveola(GO:0005901)
0.0 0.1 GO:0002139 stereocilia coupling link(GO:0002139) periciliary membrane compartment(GO:1990075)
0.0 0.2 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.6 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.5 GO:0005922 connexon complex(GO:0005922)
0.0 0.1 GO:0005927 muscle tendon junction(GO:0005927)
0.0 0.4 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.3 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.3 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.6 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.3 GO:0032433 filopodium tip(GO:0032433)
0.0 0.5 GO:0043194 axon initial segment(GO:0043194)
0.0 0.1 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.2 GO:0097512 cardiac myofibril(GO:0097512)
0.0 1.0 GO:0015030 Cajal body(GO:0015030)
0.0 0.1 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.1 GO:0035061 perichromatin fibrils(GO:0005726) interchromatin granule(GO:0035061)
0.0 0.2 GO:0005883 neurofilament(GO:0005883)
0.0 0.2 GO:0046581 intercellular canaliculus(GO:0046581)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.0 GO:0033691 sialic acid binding(GO:0033691)
0.3 0.8 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.2 1.3 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.1 1.4 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.1 0.4 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.1 0.5 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.1 3.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.4 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.1 0.4 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.1 0.4 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.1 0.4 GO:0047280 nicotinamide phosphoribosyltransferase activity(GO:0047280)
0.1 1.1 GO:0051434 BH3 domain binding(GO:0051434)
0.1 1.0 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 0.4 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 0.3 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309)
0.1 0.8 GO:0004849 uridine kinase activity(GO:0004849)
0.1 0.4 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 0.2 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.1 0.7 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.1 0.7 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.1 0.6 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.2 GO:0019107 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
0.0 0.5 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.3 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.7 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.3 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 0.5 GO:0030284 estrogen receptor activity(GO:0030284)
0.0 0.4 GO:0005221 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.6 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.3 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.1 GO:0002046 opsin binding(GO:0002046)
0.0 4.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.6 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.5 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.4 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.7 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 1.2 GO:0005109 frizzled binding(GO:0005109)
0.0 0.1 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.2 GO:0035184 histone threonine kinase activity(GO:0035184)
0.0 0.9 GO:0001848 complement binding(GO:0001848)
0.0 0.2 GO:0070728 leucine binding(GO:0070728)
0.0 0.5 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.1 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.0 0.7 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.2 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.1 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.0 1.8 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.2 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.5 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.2 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 0.4 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 0.9 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.7 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.4 GO:0005243 gap junction channel activity(GO:0005243)
0.0 1.5 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.8 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.1 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.2 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.3 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 1.0 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 1.2 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.4 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.1 GO:0016531 copper chaperone activity(GO:0016531)
0.0 0.2 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 0.2 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.3 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.2 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.1 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.3 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.2 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.5 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 1.3 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.1 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.1 GO:0001595 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0 0.1 GO:0031781 melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0 0.5 GO:0070888 E-box binding(GO:0070888)
0.0 0.1 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.8 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.9 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.1 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0 0.4 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.4 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.1 GO:0042015 interleukin-20 binding(GO:0042015)
0.0 0.4 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.1 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.6 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.3 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.2 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.5 GO:0043425 bHLH transcription factor binding(GO:0043425)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.7 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 5.5 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 1.2 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.2 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 1.1 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.4 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 2.1 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.4 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.9 ST GA12 PATHWAY G alpha 12 Pathway
0.0 1.1 PID BMP PATHWAY BMP receptor signaling
0.0 0.3 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.9 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 1.9 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.9 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 5.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.4 PID ARF 3PATHWAY Arf1 pathway
0.0 0.7 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.4 PID RHODOPSIN PATHWAY Visual signal transduction: Rods

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.7 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 0.4 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.7 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.9 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.7 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.9 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 1.3 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 1.1 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 1.4 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.9 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.4 REACTOME OPSINS Genes involved in Opsins
0.0 0.5 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 1.0 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 1.0 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 1.2 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.5 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.8 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.7 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.2 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.4 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.6 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.2 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.1 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.2 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.7 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.4 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.7 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines