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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for NR3C1

Z-value: 0.95

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Transcription factors associated with NR3C1

Gene Symbol Gene ID Gene Info
ENSG00000113580.15 NR3C1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR3C1hg38_v1_chr5_-_143403297_1434033290.545.0e-03Click!

Activity profile of NR3C1 motif

Sorted Z-values of NR3C1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of NR3C1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr15_+_88635626 2.50 ENST00000379224.10
interferon stimulated exonuclease gene 20
chr19_+_4229502 1.95 ENST00000221847.6
Epstein-Barr virus induced 3
chr6_+_127577168 1.61 ENST00000329722.8
chromosome 6 open reading frame 58
chr9_+_114155526 1.46 ENST00000356083.8
collagen type XXVII alpha 1 chain
chr2_-_224982420 1.39 ENST00000645028.1
dedicator of cytokinesis 10
chr2_-_168913277 1.39 ENST00000451987.5
SPC25 component of NDC80 kinetochore complex
chr4_-_687325 1.33 ENST00000503156.5
solute carrier family 49 member 3
chr3_-_128052166 1.28 ENST00000648300.1
monoglyceride lipase
chr3_-_127822835 1.28 ENST00000453507.6
monoglyceride lipase
chr1_-_1214146 1.16 ENST00000379236.4
TNF receptor superfamily member 4
chr2_-_224947030 1.15 ENST00000409592.7
dedicator of cytokinesis 10
chr18_-_46072244 1.14 ENST00000589328.5
ENST00000409746.5
proline-serine-threonine phosphatase interacting protein 2
chr1_-_173205543 1.12 ENST00000367718.5
TNF superfamily member 4
chr14_+_96204679 1.11 ENST00000542454.2
ENST00000539359.1
ENST00000554311.2
ENST00000553811.1
bradykinin receptor B2
novel protein
chr3_-_127822455 1.09 ENST00000265052.10
monoglyceride lipase
chr1_-_150765735 0.99 ENST00000679898.1
ENST00000448301.7
ENST00000680664.1
ENST00000679512.1
ENST00000368985.8
ENST00000679582.1
cathepsin S
chr6_-_32853813 0.98 ENST00000643049.2
transporter 1, ATP binding cassette subfamily B member
chr16_+_56682461 0.98 ENST00000562939.1
ENST00000394485.5
ENST00000567563.1
metallothionein 1X
novel transcript
chr5_+_96876480 0.94 ENST00000437043.8
ENST00000379904.8
endoplasmic reticulum aminopeptidase 2
chrX_+_50204753 0.90 ENST00000376042.6
cyclin B3
chr6_-_32853618 0.90 ENST00000354258.5
transporter 1, ATP binding cassette subfamily B member
chr1_+_165827574 0.89 ENST00000367879.9
uridine-cytidine kinase 2
chr6_+_32854179 0.89 ENST00000374859.3
proteasome 20S subunit beta 9
chr5_+_114056017 0.88 ENST00000512097.9
potassium calcium-activated channel subfamily N member 2
chr1_+_165827786 0.84 ENST00000642653.1
uridine-cytidine kinase 2
chr1_-_153549238 0.84 ENST00000368713.8
S100 calcium binding protein A3
chr4_-_73998669 0.84 ENST00000296027.5
C-X-C motif chemokine ligand 5
chr8_+_53880894 0.82 ENST00000276500.4
regulator of G protein signaling 20
chr8_+_53880867 0.81 ENST00000522225.5
regulator of G protein signaling 20
chr1_+_15345084 0.80 ENST00000529606.5
forkhead associated phosphopeptide binding domain 1
chr1_-_153549120 0.79 ENST00000368712.1
S100 calcium binding protein A3
chr7_-_16833411 0.78 ENST00000412973.1
anterior gradient 2, protein disulphide isomerase family member
chr12_-_11022620 0.78 ENST00000390673.2
taste 2 receptor member 19
chr16_+_4624811 0.77 ENST00000415496.5
ENST00000262370.12
ENST00000587747.5
ENST00000399577.9
ENST00000588994.5
ENST00000586183.5
mahogunin ring finger 1
chr20_+_64063481 0.76 ENST00000415602.5
transcription elongation factor A2
chr17_-_69150062 0.75 ENST00000522787.5
ENST00000521538.5
ATP binding cassette subfamily A member 10
chr16_+_56632651 0.74 ENST00000379818.4
ENST00000570233.1
metallothionein 1M
chr5_-_59216826 0.74 ENST00000638939.1
phosphodiesterase 4D
chr16_+_33827140 0.73 ENST00000562905.2
immunoglobulin heavy variable 3/OR16-13 (non-functional)
chr16_+_84176067 0.71 ENST00000564928.1
dynein axonemal assembly factor 1
chr6_-_32838727 0.71 ENST00000652259.1
ENST00000374897.4
ENST00000620123.4
ENST00000452392.2
transporter 2, ATP binding cassette subfamily B member
novel protein, TAP2-HLA-DOB readthrough
chr6_-_27867581 0.70 ENST00000331442.5
H1.5 linker histone, cluster member
chr11_-_60243103 0.68 ENST00000651255.1
membrane spanning 4-domains A4E
chr12_+_112978562 0.68 ENST00000680122.1
2'-5'-oligoadenylate synthetase 2
chr17_+_42798779 0.67 ENST00000585355.5
cyclin N-terminal domain containing 1
chr2_-_89213917 0.67 ENST00000498435.1
immunoglobulin kappa variable 1-27
chr11_+_5689780 0.66 ENST00000379965.8
ENST00000454828.5
tripartite motif containing 22
chr19_+_8052752 0.66 ENST00000315626.6
ENST00000253451.9
C-C motif chemokine ligand 25
chr19_+_14072754 0.64 ENST00000587086.2
MISP family member 3
chr6_-_159693228 0.64 ENST00000367054.6
ENST00000367055.8
ENST00000538183.7
ENST00000444946.6
ENST00000452684.2
superoxide dismutase 2
chr19_+_35139440 0.64 ENST00000455515.6
FXYD domain containing ion transport regulator 1
chr19_+_35139724 0.62 ENST00000588715.5
ENST00000588607.5
FXYD domain containing ion transport regulator 1
chr19_+_8053000 0.61 ENST00000390669.7
C-C motif chemokine ligand 25
chr16_+_56625775 0.60 ENST00000330439.7
ENST00000568293.1
metallothionein 1E
chr19_+_35140022 0.60 ENST00000588081.5
ENST00000589121.1
FXYD domain containing ion transport regulator 1
chr2_+_27496830 0.59 ENST00000264717.7
glucokinase regulator
chr6_+_32844108 0.59 ENST00000458296.2
ENST00000413039.6
ENST00000412095.1
ENST00000395330.5
PSMB8 antisense RNA 1 (head to head)
proteasome 20S subunit beta 9
chr3_-_112975018 0.59 ENST00000471858.5
ENST00000308611.8
ENST00000295863.4
CD200 receptor 1
chr6_-_3227643 0.58 ENST00000259818.8
tubulin beta 2B class IIb
chr1_-_183653307 0.58 ENST00000308641.6
apolipoprotein B mRNA editing enzyme catalytic polypeptide like 4
chr3_-_190449782 0.58 ENST00000354905.3
transmembrane protein 207
chr10_+_69088096 0.57 ENST00000242465.4
serglycin
chr3_+_119146184 0.57 ENST00000460150.1
testis expressed 55
chr1_-_27490045 0.57 ENST00000536657.1
WASP family member 2
chr9_-_34372832 0.57 ENST00000379142.3
myogenesis regulating glycosidase (putative)
chr1_-_173207322 0.56 ENST00000281834.4
TNF superfamily member 4
chr16_+_84175933 0.55 ENST00000569735.1
dynein axonemal assembly factor 1
chr8_-_10655137 0.55 ENST00000382483.4
RP1 like 1
chr16_+_30201057 0.55 ENST00000569485.5
sulfotransferase family 1A member 3
chr20_-_56525925 0.53 ENST00000243913.8
glucosaminyl (N-acetyl) transferase family member 7
chr17_+_76384601 0.53 ENST00000592299.6
ENST00000590959.5
ENST00000323374.8
sphingosine kinase 1
chr15_+_67125707 0.53 ENST00000540846.6
SMAD family member 3
chr8_+_11494367 0.52 ENST00000259089.9
ENST00000529894.1
BLK proto-oncogene, Src family tyrosine kinase
chr21_-_36480117 0.51 ENST00000399135.6
claudin 14
chr22_+_36913620 0.51 ENST00000403662.8
ENST00000262825.9
colony stimulating factor 2 receptor subunit beta
chr6_-_136792466 0.51 ENST00000359015.5
mitogen-activated protein kinase kinase kinase 5
chr21_-_36480060 0.51 ENST00000399137.5
claudin 14
chr10_+_5364955 0.51 ENST00000380433.5
urocortin 3
chr7_+_20615653 0.50 ENST00000404938.7
ATP binding cassette subfamily B member 5
chr16_+_56651885 0.50 ENST00000334346.3
ENST00000562399.1
metallothionein 1B
chr17_-_74868616 0.50 ENST00000579893.1
ENST00000544854.5
ferredoxin reductase
chr14_+_24147474 0.49 ENST00000324103.11
ENST00000559260.5
ring finger protein 31
chr3_-_58577367 0.49 ENST00000464064.5
ENST00000360997.7
family with sequence similarity 107 member A
chr7_-_135728177 0.49 ENST00000682651.1
ENST00000354042.8
solute carrier family 13 member 4
chr4_+_73481737 0.49 ENST00000226355.5
afamin
chr15_+_40351026 0.48 ENST00000448599.2
proline, histidine and glycine rich 1
chr1_+_78649818 0.47 ENST00000370747.9
ENST00000438486.1
interferon induced protein 44
chr3_-_58577648 0.47 ENST00000394481.5
family with sequence similarity 107 member A
chr7_-_103074816 0.46 ENST00000379305.7
ENST00000379308.7
F-box and leucine rich repeat protein 13
chr17_+_76385256 0.45 ENST00000392496.3
sphingosine kinase 1
chr1_+_169368175 0.45 ENST00000367808.8
ENST00000426663.1
basic leucine zipper nuclear factor 1
chr15_+_49621004 0.44 ENST00000403028.8
ENST00000558653.5
ENST00000559164.5
ENST00000560632.5
ENST00000559405.5
ENST00000251250.7
DTW domain containing 1
chr9_-_131709721 0.44 ENST00000372190.7
Rap guanine nucleotide exchange factor 1
chr7_-_138627444 0.43 ENST00000463557.1
SVOP like
chr22_-_16592810 0.43 ENST00000359963.4
chaperonin containing TCP1 subunit 8 like 2
chr8_+_36784324 0.43 ENST00000523973.5
ENST00000399881.8
potassium calcium-activated channel subfamily U member 1
chr15_+_75347727 0.43 ENST00000565051.5
ENST00000564257.1
ENST00000567005.1
nei like DNA glycosylase 1
chr11_-_3057386 0.43 ENST00000529772.5
ENST00000278224.13
ENST00000380525.9
cysteinyl-tRNA synthetase 1
chrX_+_120158600 0.42 ENST00000371388.5
Rhox homeobox family member 2
chr2_+_151409878 0.42 ENST00000453091.6
ENST00000428287.6
ENST00000444746.7
ENST00000243326.9
ENST00000414861.6
replication timing regulatory factor 1
chr3_-_71130963 0.41 ENST00000649695.2
forkhead box P1
chr2_-_2326378 0.41 ENST00000647618.1
myelin transcription factor 1 like
chr3_-_71130892 0.41 ENST00000491238.7
ENST00000674446.1
forkhead box P1
chr14_+_75632610 0.41 ENST00000555027.1
FLVCR heme transporter 2
chr16_+_50696999 0.41 ENST00000300589.6
nucleotide binding oligomerization domain containing 2
chr17_-_1829818 0.41 ENST00000305513.12
SET and MYND domain containing 4
chr5_-_59586393 0.41 ENST00000505453.1
ENST00000360047.9
phosphodiesterase 4D
chr11_-_111912871 0.40 ENST00000528628.5
crystallin alpha B
chr7_+_26152188 0.40 ENST00000056233.4
nuclear factor, erythroid 2 like 3
chr19_-_39934626 0.40 ENST00000616721.6
Fc fragment of IgG binding protein
chrX_+_9463272 0.40 ENST00000407597.7
ENST00000380961.5
ENST00000424279.6
transducin beta like 1 X-linked
chr14_+_72926377 0.40 ENST00000353777.7
ENST00000358377.7
ENST00000394234.6
ENST00000509153.5
ENST00000555042.5
DDB1 and CUL4 associated factor 4
chr10_+_88990736 0.40 ENST00000357339.6
ENST00000652046.1
ENST00000355279.2
Fas cell surface death receptor
chr15_-_78944985 0.40 ENST00000615999.5
ENST00000677789.1
ENST00000676880.1
ENST00000677936.1
ENST00000220166.10
ENST00000677810.1
ENST00000678644.1
ENST00000677534.1
ENST00000677316.1
cathepsin H
chr5_+_68292562 0.40 ENST00000523872.1
phosphoinositide-3-kinase regulatory subunit 1
chr4_+_80197493 0.39 ENST00000415738.3
PR/SET domain 8
chrX_+_3066833 0.39 ENST00000359361.2
arylsulfatase F
chr14_-_52791597 0.39 ENST00000216410.8
ENST00000557604.1
glucosamine-phosphate N-acetyltransferase 1
chrX_-_153446051 0.39 ENST00000370231.3
three prime repair exonuclease 2
chr19_-_52962837 0.39 ENST00000391786.6
ENST00000357666.8
ENST00000438970.6
ENST00000270457.8
ENST00000535506.5
ENST00000444460.7
ENST00000457013.6
zinc finger protein 816
chr12_+_104303726 0.38 ENST00000527879.2
EP300 interacting inhibitor of differentiation 3
chr8_-_22156789 0.38 ENST00000306317.7
leucine rich repeat LGI family member 3
chr11_-_34511710 0.38 ENST00000620316.4
ENST00000312319.6
E74 like ETS transcription factor 5
chr10_+_113679839 0.38 ENST00000369318.8
ENST00000369315.5
caspase 7
chr6_-_27312258 0.38 ENST00000444565.2
POM121 transmembrane nucleoporin like 2
chr8_-_22156741 0.37 ENST00000424267.6
leucine rich repeat LGI family member 3
chr16_+_56608577 0.37 ENST00000245185.6
ENST00000561491.1
metallothionein 2A
chr6_-_17987463 0.37 ENST00000378814.9
ENST00000636847.1
ENST00000378843.6
ENST00000378826.6
ENST00000502704.2
ENST00000259711.11
kinesin family member 13A
chr13_+_87671354 0.37 ENST00000683689.1
SLIT and NTRK like family member 5
chr18_+_34818436 0.37 ENST00000599844.5
ENST00000679731.1
dystrobrevin alpha
chr1_+_109539865 0.36 ENST00000618721.4
ENST00000527748.5
ENST00000616874.1
G protein-coupled receptor 61
chr2_+_197705353 0.36 ENST00000282276.8
methionyl-tRNA synthetase 2, mitochondrial
chrX_+_152914426 0.36 ENST00000318504.11
ENST00000449285.6
ENST00000539731.5
ENST00000535861.5
ENST00000370268.8
ENST00000370270.6
zinc finger protein 185 with LIM domain
chr2_+_85753984 0.36 ENST00000306279.4
atonal bHLH transcription factor 8
chr3_+_119146159 0.35 ENST00000295622.6
testis expressed 55
chr14_+_93333210 0.35 ENST00000256339.8
unc-79 homolog, NALCN channel complex subunit
chr2_-_89297785 0.35 ENST00000465170.1
immunoglobulin kappa variable 1-37 (non-functional)
chr6_-_154510675 0.35 ENST00000607772.6
CNKSR family member 3
chr2_-_2326210 0.34 ENST00000647755.1
myelin transcription factor 1 like
chr15_+_74788542 0.34 ENST00000567571.5
C-terminal Src kinase
chr13_+_76952467 0.34 ENST00000449753.2
aconitate decarboxylase 1
chr2_+_17878637 0.34 ENST00000304101.9
potassium voltage-gated channel modifier subfamily S member 3
chr3_+_130931893 0.34 ENST00000504612.5
ATPase secretory pathway Ca2+ transporting 1
chr16_+_3065380 0.34 ENST00000551122.5
ENST00000548807.5
ENST00000528163.6
interleukin 32
chr6_+_31670379 0.34 ENST00000409525.1
lymphocyte antigen 6 family member G5B
chr3_+_156674579 0.34 ENST00000295924.12
TCDD inducible poly(ADP-ribose) polymerase
chr4_-_78939352 0.33 ENST00000512733.5
progestin and adipoQ receptor family member 3
chr6_-_89217339 0.33 ENST00000454853.7
gamma-aminobutyric acid type A receptor subunit rho1
chr6_+_69866546 0.33 ENST00000620364.5
collagen type XIX alpha 1 chain
chr22_-_26479664 0.33 ENST00000402105.7
HPS4 biogenesis of lysosomal organelles complex 3 subunit 2
chr1_-_155300979 0.33 ENST00000392414.7
pyruvate kinase L/R
chr1_-_173824322 0.33 ENST00000356198.6
centromere protein L
chr3_-_69052309 0.32 ENST00000398559.7
ENST00000646708.1
ENST00000646304.1
TATA element modulatory factor 1
chr7_+_134646845 0.32 ENST00000344924.8
bisphosphoglycerate mutase
chr11_+_107591077 0.32 ENST00000531234.5
ENST00000265840.12
ELMO domain containing 1
chr18_+_24113341 0.32 ENST00000540918.2
tetratricopeptide repeat domain 39C
chr4_+_37891060 0.32 ENST00000261439.9
ENST00000508802.5
ENST00000402522.1
TBC1 domain family member 1
chr1_-_205850125 0.32 ENST00000367136.5
peptidase M20 domain containing 1
chr22_+_50738198 0.31 ENST00000216139.10
ENST00000529621.1
acrosin
chr22_+_24607638 0.31 ENST00000432867.5
gamma-glutamyltransferase 1
chr18_+_74499861 0.31 ENST00000324301.12
carnosine dipeptidase 2
chr7_+_134646798 0.31 ENST00000418040.5
ENST00000393132.2
bisphosphoglycerate mutase
chr11_-_9265078 0.31 ENST00000530044.5
ENST00000679568.1
ENST00000680294.1
ENST00000681203.1
DENN domain containing 5A
chr11_-_47352693 0.31 ENST00000256993.8
ENST00000399249.6
ENST00000545968.6
myosin binding protein C3
chr17_-_3063607 0.31 ENST00000575751.1
olfactory receptor family 1 subfamily D member 5
chr5_+_134114673 0.31 ENST00000342854.10
ENST00000395029.5
transcription factor 7
chr1_+_15617415 0.31 ENST00000480945.6
DNA damage inducible 1 homolog 2
chrX_-_23743201 0.30 ENST00000492081.1
ENST00000379303.10
ENST00000336430.11
acyl-CoA thioesterase 9
chr14_-_52069039 0.30 ENST00000216286.10
nidogen 2
chr12_-_6342020 0.30 ENST00000540022.5
ENST00000536194.1
TNF receptor superfamily member 1A
chr4_+_69280472 0.30 ENST00000335568.10
ENST00000511240.1
UDP glucuronosyltransferase family 2 member B28
chr17_+_75979211 0.30 ENST00000397640.6
ENST00000588202.5
ENST00000590676.1
ENST00000586891.1
TEN1 subunit of CST complex
chr1_-_146144804 0.30 ENST00000583866.9
ENST00000617010.2
NBPF member 10
chr3_+_9902619 0.30 ENST00000421412.5
interleukin 17 receptor E
chr13_-_33350619 0.30 ENST00000439831.1
ENST00000567873.1
StAR related lipid transfer domain containing 13
chr11_+_34642468 0.30 ENST00000527935.1
ETS homologous factor
chr3_-_11582330 0.30 ENST00000451674.6
vestigial like family member 4
chr9_+_122159886 0.30 ENST00000373764.8
ENST00000536616.5
MORN repeat containing 5
chr22_+_22357739 0.30 ENST00000390294.2
immunoglobulin lambda variable 1-47
chr10_+_113679523 0.29 ENST00000345633.8
ENST00000614447.4
ENST00000369321.6
caspase 7
chr2_+_90154073 0.29 ENST00000611391.1
immunoglobulin kappa variable 1D-13
chr11_+_308408 0.29 ENST00000399815.2
novel protein
chr1_-_222712428 0.29 ENST00000355727.3
ENST00000340020.11
axin interactor, dorsalization associated
chr12_+_100794769 0.29 ENST00000392977.8
ENST00000546991.1
ENST00000392979.7
anoctamin 4
chr1_-_160523204 0.29 ENST00000368055.1
ENST00000368057.8
ENST00000368059.7
SLAM family member 6
chr14_-_106235582 0.29 ENST00000390607.2
immunoglobulin heavy variable 3-21
chr2_+_89936859 0.29 ENST00000474213.1
immunoglobulin kappa variable 2D-30
chr4_-_155376797 0.29 ENST00000650955.1
ENST00000515654.5
microtubule associated protein 9
chr18_+_58341038 0.29 ENST00000679791.1
NEDD4 like E3 ubiquitin protein ligase
chr16_-_12803785 0.29 ENST00000433677.6
ENST00000261660.4
ENST00000381774.9
calcineurin like phosphoesterase domain containing 1
chr17_+_59155726 0.29 ENST00000578777.5
ENST00000577457.1
ENST00000582995.5
ENST00000262293.9
ENST00000614081.1
proline rich 11
chr15_-_72197772 0.29 ENST00000309731.12
GRAM domain containing 2A
chr14_-_106811131 0.29 ENST00000424969.2
immunoglobulin heavy variable 3-74
chr1_+_155613221 0.29 ENST00000462250.2
misato mitochondrial distribution and morphology regulator 1
chr14_-_106130061 0.29 ENST00000390602.3
immunoglobulin heavy variable 3-13
chr2_+_26034069 0.29 ENST00000264710.5
RAB10, member RAS oncogene family
chr4_+_146638890 0.29 ENST00000281321.3
POU class 4 homeobox 2
chr11_-_125778788 0.28 ENST00000436890.2
prostate and testis expressed 2
chr1_-_27366858 0.28 ENST00000374040.7
mitogen-activated protein kinase kinase kinase 6
chr12_-_6342066 0.28 ENST00000162749.7
ENST00000440083.6
TNF receptor superfamily member 1A

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:0046967 cytosol to ER transport(GO:0046967)
0.6 2.5 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.6 1.7 GO:2000523 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.4 1.7 GO:0046035 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.4 3.7 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.3 1.0 GO:0034769 basement membrane disassembly(GO:0034769)
0.3 1.0 GO:0046521 sphingoid catabolic process(GO:0046521)
0.3 1.9 GO:0010732 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.2 1.5 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.2 1.3 GO:0036018 cellular response to erythropoietin(GO:0036018)
0.2 0.6 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.2 0.3 GO:0060434 bronchus morphogenesis(GO:0060434)
0.2 0.5 GO:0038156 interleukin-5-mediated signaling pathway(GO:0038043) interleukin-3-mediated signaling pathway(GO:0038156)
0.2 0.5 GO:0048058 compound eye corneal lens development(GO:0048058)
0.2 1.3 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.2 0.8 GO:0060480 lung goblet cell differentiation(GO:0060480)
0.2 1.2 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.1 1.4 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1 1.1 GO:1902219 negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.1 0.6 GO:0003069 age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
0.1 0.6 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.1 2.1 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 0.5 GO:0030035 microspike assembly(GO:0030035)
0.1 0.6 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.1 1.8 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.1 0.6 GO:0002606 positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.1 0.4 GO:0003095 pressure natriuresis(GO:0003095)
0.1 0.4 GO:0060448 dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.1 0.5 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.1 0.3 GO:0045196 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200) establishment of protein localization to endoplasmic reticulum membrane(GO:0097051)
0.1 0.3 GO:0005989 lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989)
0.1 0.3 GO:0035281 pre-miRNA export from nucleus(GO:0035281)
0.1 0.5 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.1 0.3 GO:1900154 regulation of bone trabecula formation(GO:1900154) negative regulation of bone trabecula formation(GO:1900155)
0.1 0.5 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.1 0.3 GO:1901257 negative regulation of interleukin-3 production(GO:0032712) negative regulation of granulocyte colony-stimulating factor production(GO:0071656) negative regulation of macrophage colony-stimulating factor production(GO:1901257)
0.1 0.3 GO:0030961 peptidyl-arginine hydroxylation(GO:0030961)
0.1 0.3 GO:0007060 male meiosis chromosome segregation(GO:0007060)
0.1 0.7 GO:0072734 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.1 0.8 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.1 0.3 GO:0048073 regulation of eye pigmentation(GO:0048073)
0.1 0.5 GO:0006535 cysteine biosynthetic process from serine(GO:0006535)
0.1 0.4 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.1 0.7 GO:0036337 Fas signaling pathway(GO:0036337)
0.1 2.0 GO:0071294 cellular response to zinc ion(GO:0071294)
0.1 0.4 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.1 0.3 GO:0035936 testosterone secretion(GO:0035936) regulation of testosterone secretion(GO:2000843) positive regulation of testosterone secretion(GO:2000845)
0.1 0.3 GO:0043605 cellular amide catabolic process(GO:0043605)
0.1 0.2 GO:0017198 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.1 0.5 GO:0061589 calcium activated phosphatidylserine scrambling(GO:0061589)
0.1 1.1 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.1 0.2 GO:0046110 xanthine metabolic process(GO:0046110)
0.1 0.6 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1 1.2 GO:0051024 positive regulation of immunoglobulin secretion(GO:0051024)
0.1 0.1 GO:0072061 inner medullary collecting duct development(GO:0072061)
0.1 0.3 GO:1902869 regulation of amacrine cell differentiation(GO:1902869)
0.1 0.3 GO:0009213 pyrimidine nucleoside triphosphate catabolic process(GO:0009149) pyrimidine deoxyribonucleoside triphosphate catabolic process(GO:0009213)
0.1 0.2 GO:0072276 metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.1 0.6 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
0.1 0.2 GO:0043012 regulation of fusion of sperm to egg plasma membrane(GO:0043012)
0.1 0.3 GO:0007341 penetration of zona pellucida(GO:0007341)
0.1 0.9 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.1 0.4 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.1 0.5 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.1 0.2 GO:0042418 epinephrine biosynthetic process(GO:0042418)
0.1 0.4 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.1 0.7 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1 0.2 GO:1904692 positive regulation of type B pancreatic cell proliferation(GO:1904692)
0.1 0.3 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.1 0.2 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.1 0.6 GO:0019885 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.1 0.2 GO:1901876 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.1 0.7 GO:0018377 protein myristoylation(GO:0018377)
0.1 0.4 GO:0001712 ectoderm formation(GO:0001705) ectodermal cell fate commitment(GO:0001712)
0.1 0.4 GO:0019344 cysteine biosynthetic process(GO:0019344)
0.1 0.2 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.1 0.2 GO:0006408 snRNA export from nucleus(GO:0006408)
0.1 0.2 GO:0061358 negative regulation of Wnt protein secretion(GO:0061358)
0.0 0.3 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.0 0.3 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0 0.8 GO:0008272 sulfate transport(GO:0008272)
0.0 0.6 GO:1902669 positive regulation of axon guidance(GO:1902669)
0.0 0.8 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.1 GO:2000276 negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276) cell proliferation involved in heart valve development(GO:2000793)
0.0 0.1 GO:1990180 mitochondrial tRNA 3'-end processing(GO:1990180)
0.0 0.2 GO:0000023 maltose metabolic process(GO:0000023)
0.0 0.3 GO:0045425 positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425)
0.0 0.3 GO:0032971 regulation of muscle filament sliding(GO:0032971)
0.0 0.0 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.0 0.1 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.0 0.1 GO:2001303 regulation of engulfment of apoptotic cell(GO:1901074) lipoxin biosynthetic process(GO:2001301) lipoxin A4 metabolic process(GO:2001302) lipoxin A4 biosynthetic process(GO:2001303)
0.0 0.2 GO:1900533 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.0 0.6 GO:0071550 death-inducing signaling complex assembly(GO:0071550)
0.0 1.5 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.1 GO:0051365 cellular response to potassium ion starvation(GO:0051365)
0.0 0.1 GO:1902232 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535) regulation of positive thymic T cell selection(GO:1902232)
0.0 0.2 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 0.4 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.0 0.2 GO:1903826 arginine transmembrane transport(GO:1903826)
0.0 0.3 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 0.1 GO:0090301 regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.0 0.3 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.1 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
0.0 0.0 GO:1903015 regulation of exo-alpha-sialidase activity(GO:1903015)
0.0 0.1 GO:1905033 positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903762) positive regulation of ventricular cardiac muscle cell action potential(GO:1903947) positive regulation of membrane repolarization during ventricular cardiac muscle cell action potential(GO:1905026) positive regulation of membrane repolarization during cardiac muscle cell action potential(GO:1905033)
0.0 0.2 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.0 0.4 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.0 0.1 GO:0046351 disaccharide biosynthetic process(GO:0046351)
0.0 0.1 GO:0031064 negative regulation of histone deacetylation(GO:0031064)
0.0 0.1 GO:0035498 carnosine metabolic process(GO:0035498)
0.0 0.4 GO:0045836 positive regulation of meiotic nuclear division(GO:0045836)
0.0 0.4 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.0 0.2 GO:0035234 ectopic germ cell programmed cell death(GO:0035234) pyroptosis(GO:0070269)
0.0 0.1 GO:0018282 metal incorporation into metallo-sulfur cluster(GO:0018282) iron incorporation into metallo-sulfur cluster(GO:0018283)
0.0 0.8 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.0 1.0 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.0 0.2 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.2 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.1 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.0 0.1 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.0 0.1 GO:0072302 negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302)
0.0 0.1 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.0 0.1 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.3 GO:0097396 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.0 0.1 GO:0002316 follicular B cell differentiation(GO:0002316)
0.0 0.1 GO:1904100 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.0 1.2 GO:0048665 neuron fate specification(GO:0048665)
0.0 0.0 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.0 0.2 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0 0.5 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.0 0.4 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.1 GO:0019072 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.0 1.3 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.1 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.1 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.0 0.2 GO:2000402 negative regulation of lymphocyte migration(GO:2000402)
0.0 0.1 GO:0007538 primary sex determination(GO:0007538)
0.0 0.5 GO:0038180 nerve growth factor signaling pathway(GO:0038180)
0.0 0.1 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.0 0.1 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0 0.1 GO:0003408 optic cup formation involved in camera-type eye development(GO:0003408)
0.0 0.4 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.3 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.0 0.1 GO:0061570 dADP phosphorylation(GO:0006174) dGDP phosphorylation(GO:0006186) AMP phosphorylation(GO:0006756) CDP phosphorylation(GO:0061508) dAMP phosphorylation(GO:0061565) CMP phosphorylation(GO:0061566) dCMP phosphorylation(GO:0061567) GDP phosphorylation(GO:0061568) UDP phosphorylation(GO:0061569) dCDP phosphorylation(GO:0061570) TDP phosphorylation(GO:0061571)
0.0 0.5 GO:0045838 positive regulation of membrane potential(GO:0045838)
0.0 0.4 GO:0051531 NFAT protein import into nucleus(GO:0051531)
0.0 0.4 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.0 0.2 GO:1902459 positive regulation of stem cell population maintenance(GO:1902459)
0.0 0.1 GO:0044376 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.0 0.1 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
0.0 0.3 GO:0032740 positive regulation of interleukin-17 production(GO:0032740)
0.0 0.1 GO:1901420 negative regulation of response to alcohol(GO:1901420)
0.0 0.1 GO:0072656 maintenance of protein location in mitochondrion(GO:0072656)
0.0 0.4 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.7 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.0 0.5 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.1 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.2 GO:0061709 reticulophagy(GO:0061709)
0.0 0.3 GO:0021670 lateral ventricle development(GO:0021670)
0.0 0.1 GO:0007161 calcium-independent cell-matrix adhesion(GO:0007161)
0.0 0.5 GO:0051450 myoblast proliferation(GO:0051450)
0.0 0.5 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.0 0.1 GO:0001869 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.0 0.7 GO:0061641 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.9 GO:0035825 reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.0 0.1 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309) positive regulation of histone H3-K9 trimethylation(GO:1900114)
0.0 1.9 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.3 GO:0048262 determination of dorsal/ventral asymmetry(GO:0048262)
0.0 0.3 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.3 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
0.0 0.1 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.1 GO:0046520 sphingoid biosynthetic process(GO:0046520)
0.0 0.2 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.1 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.2 GO:0030916 otic vesicle formation(GO:0030916)
0.0 0.1 GO:0006726 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.0 0.1 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.0 0.4 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.1 GO:1903936 cellular response to sodium arsenite(GO:1903936)
0.0 0.0 GO:0036100 leukotriene catabolic process(GO:0036100) leukotriene B4 catabolic process(GO:0036101) leukotriene B4 metabolic process(GO:0036102) icosanoid catabolic process(GO:1901523) fatty acid derivative catabolic process(GO:1901569)
0.0 0.2 GO:0045651 positive regulation of macrophage differentiation(GO:0045651)
0.0 0.2 GO:0051382 kinetochore assembly(GO:0051382)
0.0 1.0 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.4 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.3 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.0 0.2 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.1 GO:0060029 convergent extension involved in organogenesis(GO:0060029)
0.0 0.0 GO:0052422 modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.0 0.0 GO:0050883 musculoskeletal movement, spinal reflex action(GO:0050883)
0.0 0.4 GO:0021756 striatum development(GO:0021756)
0.0 0.1 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.7 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.0 0.6 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 0.3 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.0 GO:0071422 succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422)
0.0 0.7 GO:0035036 sperm-egg recognition(GO:0035036)
0.0 0.6 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.1 GO:0046203 spermidine catabolic process(GO:0046203)
0.0 0.1 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.0 0.1 GO:1903301 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.0 0.1 GO:2000400 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.0 0.1 GO:0032907 transforming growth factor beta3 production(GO:0032907) regulation of transforming growth factor beta3 production(GO:0032910)
0.0 0.1 GO:0009443 pyridoxal 5'-phosphate salvage(GO:0009443)
0.0 0.2 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 0.1 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.0 0.2 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 0.1 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.2 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.3 GO:0015671 oxygen transport(GO:0015671)
0.0 0.1 GO:0015808 L-alanine transport(GO:0015808)
0.0 0.4 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 0.0 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.0 0.2 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.1 GO:0002860 positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0 0.0 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.0 0.0 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.0 0.2 GO:0035090 telencephalon regionalization(GO:0021978) maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0 0.2 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 0.1 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.3 GO:0048311 mitochondrion distribution(GO:0048311)
0.0 0.1 GO:0060026 convergent extension(GO:0060026)
0.0 0.1 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.0 0.2 GO:0060742 epithelial cell differentiation involved in prostate gland development(GO:0060742)
0.0 0.2 GO:0008089 anterograde axonal transport(GO:0008089)
0.0 0.1 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.1 GO:1903943 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.0 GO:1901053 sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053)
0.0 0.1 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.1 GO:0043606 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.0 0.3 GO:0032211 negative regulation of telomere maintenance via telomerase(GO:0032211)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.3 GO:0042825 TAP complex(GO:0042825)
0.2 1.4 GO:0031262 Ndc80 complex(GO:0031262)
0.2 1.7 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 0.4 GO:0000229 cytoplasmic chromosome(GO:0000229)
0.1 1.0 GO:0001939 female pronucleus(GO:0001939)
0.1 0.4 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.1 0.3 GO:0031085 BLOC-3 complex(GO:0031085)
0.1 0.3 GO:0043159 acrosomal matrix(GO:0043159)
0.1 1.5 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 0.5 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.1 0.4 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.1 0.7 GO:0036021 endolysosome lumen(GO:0036021)
0.1 2.0 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 0.3 GO:0042565 RNA nuclear export complex(GO:0042565)
0.1 0.6 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.1 0.3 GO:1990879 CST complex(GO:1990879)
0.1 0.5 GO:0071797 LUBAC complex(GO:0071797)
0.1 0.2 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.1 0.5 GO:0043196 varicosity(GO:0043196)
0.1 0.2 GO:0005745 m-AAA complex(GO:0005745)
0.1 0.5 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 0.3 GO:0043291 RAVE complex(GO:0043291)
0.1 0.8 GO:0031209 SCAR complex(GO:0031209)
0.1 0.2 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0 0.6 GO:0000235 astral microtubule(GO:0000235) aster(GO:0005818)
0.0 0.2 GO:0097454 Schwann cell microvillus(GO:0097454)
0.0 0.3 GO:0002081 outer acrosomal membrane(GO:0002081)
0.0 0.1 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.1 GO:0008623 CHRAC(GO:0008623)
0.0 0.4 GO:0036157 outer dynein arm(GO:0036157)
0.0 3.2 GO:0015030 Cajal body(GO:0015030)
0.0 0.4 GO:0097208 alveolar lamellar body(GO:0097208)
0.0 0.1 GO:0070701 mucus layer(GO:0070701)
0.0 0.2 GO:0097169 IPAF inflammasome complex(GO:0072557) AIM2 inflammasome complex(GO:0097169)
0.0 0.4 GO:0005638 lamin filament(GO:0005638)
0.0 0.2 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.0 0.8 GO:0042588 zymogen granule(GO:0042588)
0.0 0.2 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.0 0.2 GO:0031415 NatA complex(GO:0031415)
0.0 0.2 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 0.3 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.1 GO:0018444 translation release factor complex(GO:0018444)
0.0 0.8 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.4 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.2 GO:0097149 centralspindlin complex(GO:0097149)
0.0 0.1 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.0 0.2 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.1 GO:0005713 recombination nodule(GO:0005713)
0.0 0.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.9 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.3 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.2 GO:0033648 host intracellular organelle(GO:0033647) host intracellular membrane-bounded organelle(GO:0033648)
0.0 0.1 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.7 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.4 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.3 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.1 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.0 0.2 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.4 GO:0044615 nuclear pore central transport channel(GO:0044613) nuclear pore nuclear basket(GO:0044615)
0.0 0.2 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.0 0.1 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.4 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.2 GO:0045120 pronucleus(GO:0045120)
0.0 0.1 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.5 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.2 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 1.4 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.8 GO:0000791 euchromatin(GO:0000791)
0.0 0.1 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0 0.2 GO:0030914 STAGA complex(GO:0030914)
0.0 0.2 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.2 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.2 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.6 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.2 GO:0005883 neurofilament(GO:0005883)
0.0 1.2 GO:0005930 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 0.5 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.1 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.2 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.1 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.4 GO:0034706 sodium channel complex(GO:0034706)
0.0 2.4 GO:0043197 dendritic spine(GO:0043197)
0.0 0.1 GO:0070852 cell body fiber(GO:0070852)
0.0 0.3 GO:0030904 retromer complex(GO:0030904)
0.0 4.4 GO:0019898 extrinsic component of membrane(GO:0019898)
0.0 0.2 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.5 GO:0008859 exoribonuclease II activity(GO:0008859)
0.3 2.6 GO:0023029 MHC class Ib protein binding(GO:0023029)
0.2 1.3 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.2 3.8 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.2 0.5 GO:0004912 interleukin-3 receptor activity(GO:0004912) interleukin-5 receptor activity(GO:0004914)
0.2 1.0 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.2 0.5 GO:0008431 vitamin E binding(GO:0008431)
0.2 0.6 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.2 1.7 GO:0004849 uridine kinase activity(GO:0004849)
0.2 0.5 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1 1.0 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.1 0.5 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.1 0.5 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.1 0.6 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.1 0.3 GO:0004040 amidase activity(GO:0004040)
0.1 0.3 GO:0102008 cytosolic dipeptidase activity(GO:0102008)
0.1 0.3 GO:0090631 pre-miRNA transporter activity(GO:0090631)
0.1 0.9 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 0.5 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.1 0.3 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 0.5 GO:0004122 cystathionine beta-synthase activity(GO:0004122)
0.1 0.2 GO:1990190 peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.1 0.4 GO:0050051 leukotriene-B4 20-monooxygenase activity(GO:0050051)
0.1 0.4 GO:0008410 CoA-transferase activity(GO:0008410)
0.1 0.5 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.1 0.2 GO:0031862 prostanoid receptor binding(GO:0031862)
0.1 0.3 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.1 0.2 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.1 0.6 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.1 0.3 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.1 0.2 GO:0004339 glucan 1,4-alpha-glucosidase activity(GO:0004339)
0.1 0.8 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 0.2 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.1 1.6 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 0.4 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.1 0.4 GO:0001595 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.1 1.1 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.1 0.2 GO:0003963 RNA-3'-phosphate cyclase activity(GO:0003963)
0.1 0.2 GO:0038047 beta-endorphin receptor activity(GO:0004979) morphine receptor activity(GO:0038047)
0.1 0.2 GO:0033265 choline binding(GO:0033265)
0.0 0.7 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 2.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 1.4 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.1 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0 0.7 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.4 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.1 GO:0047977 hepoxilin-epoxide hydrolase activity(GO:0047977)
0.0 1.2 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 1.3 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.4 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 0.1 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.0 0.6 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.2 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.2 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.2 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0 0.3 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.2 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.5 GO:0016015 morphogen activity(GO:0016015)
0.0 2.9 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.1 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.0 0.2 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.0 1.0 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.5 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.0 0.7 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.3 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.8 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.3 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.3 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.5 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 1.3 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.1 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.0 0.6 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.9 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.7 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.4 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 1.5 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.3 GO:0032552 deoxyribonucleotide binding(GO:0032552)
0.0 0.2 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.2 GO:0070728 leucine binding(GO:0070728)
0.0 0.2 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.3 GO:0032190 acrosin binding(GO:0032190)
0.0 0.1 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.0 0.4 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.2 GO:0004966 galanin receptor activity(GO:0004966)
0.0 0.1 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.0 0.8 GO:0004812 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 0.2 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.0 0.8 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.4 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.6 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0019862 IgA binding(GO:0019862)
0.0 0.7 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.1 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0 0.1 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0 1.0 GO:0043236 laminin binding(GO:0043236)
0.0 0.2 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.1 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.0 0.1 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.7 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.2 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.1 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0 0.2 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.1 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 0.1 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.0 0.6 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.1 GO:0008158 hedgehog receptor activity(GO:0008158)
0.0 2.0 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.4 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.0 0.1 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
0.0 0.0 GO:0002134 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
0.0 0.2 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.0 0.7 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.1 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.1 GO:1990405 protein antigen binding(GO:1990405)
0.0 0.2 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.1 GO:0099589 serotonin receptor activity(GO:0099589)
0.0 0.1 GO:0001032 RNA polymerase III type 3 promoter DNA binding(GO:0001032)
0.0 0.2 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.1 GO:0016530 metallochaperone activity(GO:0016530)
0.0 0.4 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.6 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.1 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 0.2 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.1 GO:0070363 mitochondrial light strand promoter sense binding(GO:0070363)
0.0 0.1 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.2 GO:0043295 glutathione binding(GO:0043295)
0.0 0.3 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.1 GO:0045159 myosin II binding(GO:0045159)
0.0 0.2 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.4 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.5 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.1 GO:0004396 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.1 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.0 0.1 GO:0008478 pyridoxal kinase activity(GO:0008478)
0.0 0.4 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.1 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.0 0.2 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.2 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.1 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.2 GO:0019841 retinol binding(GO:0019841)
0.0 0.5 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.1 GO:0016749 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.0 0.0 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.0 0.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.4 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.1 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.0 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0 0.0 GO:0015141 succinate transmembrane transporter activity(GO:0015141)
0.0 0.0 GO:0008480 sarcosine dehydrogenase activity(GO:0008480)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.9 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.9 PID IL5 PATHWAY IL5-mediated signaling events
0.0 2.9 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 2.1 NABA COLLAGENS Genes encoding collagen proteins
0.0 2.2 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 1.5 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.6 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.9 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 1.2 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 1.2 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 3.9 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.7 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.4 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.5 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.3 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 0.3 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.1 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.5 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.9 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.2 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.4 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.0 0.3 PID BMP PATHWAY BMP receptor signaling
0.0 0.4 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.2 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.5 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 3.3 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 1.0 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 1.0 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 1.6 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 1.5 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 1.5 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 1.1 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.6 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.7 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 1.9 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.0 2.1 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 2.0 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 1.3 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.8 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.4 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.6 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.6 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.2 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.4 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.8 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.6 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.3 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.5 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.3 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.9 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 0.2 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.7 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 1.8 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.2 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.3 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 1.1 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 1.1 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.1 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.0 0.4 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.5 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 1.9 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.7 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.9 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0 0.2 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.1 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.2 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 0.3 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0 0.1 REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.0 0.5 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.9 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.8 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.2 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors