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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for NR4A2

Z-value: 0.59

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Transcription factors associated with NR4A2

Gene Symbol Gene ID Gene Info
ENSG00000153234.15 NR4A2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR4A2hg38_v1_chr2_-_156332694_1563327280.213.1e-01Click!

Activity profile of NR4A2 motif

Sorted Z-values of NR4A2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of NR4A2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr2_+_227813834 2.37 ENST00000358813.5
ENST00000409189.7
C-C motif chemokine ligand 20
chr4_+_41612892 0.94 ENST00000509454.5
ENST00000396595.7
ENST00000381753.8
LIM and calponin homology domains 1
chr7_+_48088596 0.89 ENST00000416681.5
ENST00000331803.8
ENST00000432131.5
uridine phosphorylase 1
chr1_+_212565334 0.77 ENST00000366981.8
ENST00000366987.6
activating transcription factor 3
chr19_+_1407731 0.76 ENST00000592453.2
DAZ associated protein 1
chr7_+_48089257 0.75 ENST00000436673.5
ENST00000395564.9
uridine phosphorylase 1
chr4_+_41612702 0.70 ENST00000509277.5
LIM and calponin homology domains 1
chr13_-_113864062 0.68 ENST00000327773.7
growth arrest specific 6
chr8_+_37796850 0.58 ENST00000412232.3
adhesion G protein-coupled receptor A2
chr8_+_22053543 0.51 ENST00000519850.5
ENST00000381470.7
dematin actin binding protein
chr8_+_144095054 0.47 ENST00000318911.5
cytochrome c1
chr10_+_79347491 0.47 ENST00000448165.1
peptidylprolyl isomerase F
chr16_-_87493013 0.46 ENST00000671377.2
zinc finger CCHC-type containing 14
chr17_-_29176752 0.44 ENST00000533112.5
myosin XVIIIA
chr5_+_66828762 0.43 ENST00000490016.6
ENST00000403666.5
ENST00000450827.5
microtubule associated serine/threonine kinase family member 4
chr4_-_138242325 0.43 ENST00000280612.9
solute carrier family 7 member 11
chr17_+_7630094 0.40 ENST00000441599.6
ENST00000380450.9
ENST00000416273.7
ENST00000575903.5
ENST00000571153.5
ENST00000575618.5
ENST00000576152.1
ENST00000576830.5
sex hormone binding globulin
chrX_+_151694967 0.38 ENST00000448726.5
ENST00000538575.5
proline rich and Gla domain 3
chr2_+_161160299 0.37 ENST00000440506.5
ENST00000429217.5
ENST00000406287.5
ENST00000402568.5
TRAF family member associated NFKB activator
chr15_-_55270383 0.34 ENST00000396307.6
RAB27A, member RAS oncogene family
chr22_-_37484505 0.34 ENST00000442496.1
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr19_+_2328663 0.34 ENST00000614794.4
ENST00000613503.5
ENST00000610743.4
ENST00000618220.4
signal peptide peptidase like 2B
chr6_-_75363003 0.33 ENST00000370020.1
filamin A interacting protein 1
chr17_+_28744034 0.33 ENST00000444415.7
ENST00000262396.10
TNF receptor associated factor 4
chr19_-_2783308 0.33 ENST00000677562.1
ENST00000677754.1
small glutamine rich tetratricopeptide repeat containing alpha
chr7_+_112450451 0.32 ENST00000429071.5
ENST00000403825.8
ENST00000675268.1
interferon related developmental regulator 1
novel protein
chr22_+_49960760 0.32 ENST00000360612.5
Pim-3 proto-oncogene, serine/threonine kinase
chr11_+_67240047 0.31 ENST00000530342.2
lysine demethylase 2A
chr12_-_81598332 0.31 ENST00000443686.7
PTPRF interacting protein alpha 2
chr12_+_93569814 0.31 ENST00000340600.6
suppressor of cytokine signaling 2
chr2_+_216633411 0.31 ENST00000233809.9
insulin like growth factor binding protein 2
chr15_-_55270280 0.29 ENST00000564609.5
RAB27A, member RAS oncogene family
chr8_+_133113483 0.28 ENST00000521107.1
thyroglobulin
chr12_-_6606320 0.28 ENST00000642594.1
ENST00000644289.1
ENST00000645095.1
chromodomain helicase DNA binding protein 4
chr2_+_11677587 0.27 ENST00000449576.6
lipin 1
chr17_-_64390852 0.26 ENST00000563924.6
platelet and endothelial cell adhesion molecule 1
chr16_-_66918876 0.26 ENST00000570262.5
ENST00000299752.9
ENST00000394055.7
cadherin 16
chr16_-_66918839 0.26 ENST00000565235.2
ENST00000568632.5
ENST00000565796.5
cadherin 16
chr19_-_2783241 0.26 ENST00000676943.1
ENST00000589251.5
ENST00000221566.7
ENST00000676984.1
small glutamine rich tetratricopeptide repeat containing alpha
chr9_-_133479075 0.26 ENST00000414172.1
ENST00000371897.8
ENST00000371899.9
solute carrier family 2 member 6
chr22_+_30396991 0.26 ENST00000617837.4
ENST00000615189.5
ENST00000405717.7
ENST00000402592.7
SEC14 like lipid binding 2
chrX_+_136148440 0.25 ENST00000627383.2
ENST00000630084.2
four and a half LIM domains 1
chr22_-_38844020 0.25 ENST00000333039.4
neuronal pentraxin receptor
chr2_+_161160420 0.25 ENST00000392749.7
ENST00000405852.5
TRAF family member associated NFKB activator
chr10_+_49942048 0.24 ENST00000651259.3
ENST00000652716.1
translocase of inner mitochondrial membrane 23 homolog B
chr6_-_39322540 0.24 ENST00000425054.6
ENST00000373227.8
ENST00000373229.9
potassium two pore domain channel subfamily K member 16
chr20_+_44715360 0.24 ENST00000190983.5
cellular communication network factor 5
chrX_-_150898592 0.24 ENST00000355149.8
ENST00000466436.5
ENST00000370377.8
CD99 molecule like 2
chr5_+_150190035 0.24 ENST00000230671.7
ENST00000524041.1
solute carrier family 6 member 7
chr20_+_38962299 0.23 ENST00000373325.6
ENST00000373323.8
ENST00000252011.8
ENST00000615559.1
DEAH-box helicase 35
novel transcript, sense intronic to DHX35
chr14_+_21030509 0.23 ENST00000481535.5
tubulin polymerization promoting protein family member 2
chr17_-_10373002 0.23 ENST00000252172.9
ENST00000418404.8
myosin heavy chain 13
chr16_-_49664225 0.23 ENST00000535559.5
zinc finger protein 423
chr7_+_129368123 0.22 ENST00000460109.5
ENST00000474594.5
adenosylhomocysteinase like 2
chr17_+_19378476 0.22 ENST00000395604.8
ENST00000482850.1
mitogen-activated protein kinase 7
chr12_-_95790755 0.22 ENST00000343702.9
ENST00000344911.8
netrin 4
chr14_+_23322019 0.21 ENST00000557702.5
poly(A) binding protein nuclear 1
chr11_-_47449129 0.21 ENST00000298854.7
ENST00000524487.5
ENST00000529341.1
ENST00000352508.7
receptor associated protein of the synapse
chr7_+_128758947 0.21 ENST00000493278.1
calumenin
chr17_+_75979211 0.21 ENST00000397640.6
ENST00000588202.5
ENST00000590676.1
ENST00000586891.1
TEN1 subunit of CST complex
chr11_-_707063 0.20 ENST00000683307.1
DEAF1 transcription factor
chr7_+_112423137 0.20 ENST00000005558.8
ENST00000621379.4
interferon related developmental regulator 1
chr3_+_129528632 0.20 ENST00000296271.4
rhodopsin
chr11_-_78341876 0.20 ENST00000340149.6
GRB2 associated binding protein 2
chr2_-_110115811 0.20 ENST00000272462.3
mal, T cell differentiation protein like
chr19_-_15125095 0.19 ENST00000600984.5
ilvB acetolactate synthase like
chr19_+_6739650 0.18 ENST00000313285.12
ENST00000313244.14
ENST00000596758.5
thyroid hormone receptor interactor 10
chr21_+_41167774 0.18 ENST00000328735.10
ENST00000347667.5
beta-secretase 2
chr1_-_1779976 0.18 ENST00000378625.5
NAD kinase
chr19_+_42320359 0.18 ENST00000601644.1
transmembrane protein 145
chr16_+_3654683 0.17 ENST00000246949.10
deoxyribonuclease 1
chr13_-_52011337 0.17 ENST00000400366.6
ENST00000400370.8
ENST00000634844.1
ENST00000673772.1
ENST00000418097.7
ENST00000242839.10
ENST00000344297.9
ENST00000448424.7
ATPase copper transporting beta
chr22_-_36506475 0.17 ENST00000397223.4
FAD dependent oxidoreductase domain containing 2
chr21_+_41168142 0.17 ENST00000330333.11
beta-secretase 2
chr4_-_151015713 0.16 ENST00000357115.9
LPS responsive beige-like anchor protein
chr16_+_85799668 0.16 ENST00000568794.5
ENST00000562336.5
ENST00000253452.8
ENST00000561569.5
ENST00000566405.5
cytochrome c oxidase subunit 4I1
chrX_-_150898779 0.16 ENST00000613030.4
ENST00000437787.6
CD99 molecule like 2
chr6_+_32038382 0.16 ENST00000478281.5
ENST00000471671.4
ENST00000435122.3
ENST00000644719.2
cytochrome P450 family 21 subfamily A member 2
chr3_-_113746059 0.15 ENST00000477813.5
N-alpha-acetyltransferase 50, NatE catalytic subunit
chr22_-_30564889 0.15 ENST00000401975.5
ENST00000428682.5
ENST00000423299.5
galactose-3-O-sulfotransferase 1
chr1_-_8817633 0.15 ENST00000400908.7
arginine-glutamic acid dipeptide repeats
chr19_-_55363243 0.15 ENST00000424985.3
family with sequence similarity 71 member E2
chr1_+_28812160 0.14 ENST00000234961.7
opioid receptor delta 1
chr14_-_60724300 0.14 ENST00000556952.3
ENST00000216513.5
SIX homeobox 4
chr2_+_237858874 0.14 ENST00000404910.6
receptor activity modifying protein 1
chr9_-_39239174 0.14 ENST00000358144.6
contactin associated protein family member 3
chr12_-_114406133 0.14 ENST00000405440.7
T-box transcription factor 5
chr1_-_166975407 0.14 ENST00000528703.5
ENST00000525740.5
ENST00000529387.5
ENST00000469934.6
ENST00000529071.5
ENST00000526687.1
ENST00000271417.8
immunoglobulin like domain containing receptor 2
chr8_+_135457442 0.14 ENST00000355849.10
KH RNA binding domain containing, signal transduction associated 3
chr1_-_157138474 0.14 ENST00000326786.4
ETS variant transcription factor 3
chr6_-_31660735 0.14 ENST00000375911.2
chromosome 6 open reading frame 47
chr19_+_4153616 0.14 ENST00000078445.7
ENST00000595923.5
ENST00000602257.5
ENST00000602147.1
cAMP responsive element binding protein 3 like 3
chr15_+_59438149 0.14 ENST00000288228.10
ENST00000559628.5
ENST00000557914.5
ENST00000560474.5
family with sequence similarity 81 member A
chr11_-_64226129 0.14 ENST00000545812.1
ENST00000394547.7
ENST00000317459.11
tRNA phosphotransferase 1
chrX_+_154429092 0.14 ENST00000619046.5
ATPase H+ transporting accessory protein 1
chr1_+_196652022 0.13 ENST00000367429.9
ENST00000630130.2
ENST00000359637.2
complement factor H
chr1_+_155613221 0.13 ENST00000462250.2
misato mitochondrial distribution and morphology regulator 1
chr19_-_56121223 0.13 ENST00000587279.1
ENST00000610935.2
zinc finger protein 787
chr3_-_151316795 0.13 ENST00000260843.5
G protein-coupled receptor 87
chr10_+_79347460 0.13 ENST00000225174.8
peptidylprolyl isomerase F
chr4_-_110198650 0.13 ENST00000394607.7
ELOVL fatty acid elongase 6
chr11_+_76860859 0.13 ENST00000679754.1
ENST00000534206.5
ENST00000680583.1
ENST00000532485.6
ENST00000526597.5
ENST00000533873.1
alkaline ceramidase 3
chr16_+_85908988 0.13 ENST00000566369.1
interferon regulatory factor 8
chr20_+_1895365 0.13 ENST00000358771.5
signal regulatory protein alpha
chr9_+_93234923 0.13 ENST00000411624.5
WNK lysine deficient protein kinase 2
chr16_+_6019585 0.13 ENST00000547372.5
RNA binding fox-1 homolog 1
chr9_-_128127711 0.12 ENST00000449878.1
ENST00000338961.11
ENST00000678174.1
prostaglandin E synthase 2
chr12_+_51424965 0.12 ENST00000514353.7
solute carrier family 4 member 8
chr4_-_110198579 0.12 ENST00000302274.8
ELOVL fatty acid elongase 6
chr16_+_4624811 0.12 ENST00000415496.5
ENST00000262370.12
ENST00000587747.5
ENST00000399577.9
ENST00000588994.5
ENST00000586183.5
mahogunin ring finger 1
chr8_-_143944737 0.12 ENST00000398774.6
plectin
chr19_+_46347063 0.12 ENST00000012443.9
ENST00000391919.1
protein phosphatase 5 catalytic subunit
chr6_+_30626842 0.12 ENST00000318999.11
ENST00000376485.8
ENST00000330083.6
ENST00000319027.9
ENST00000376483.8
ENST00000329992.12
alpha tubulin acetyltransferase 1
chr12_-_120116730 0.12 ENST00000538903.1
ENST00000229340.10
ENST00000534951.5
RAB35, member RAS oncogene family
chr2_+_209424039 0.12 ENST00000682079.1
ENST00000199940.10
microtubule associated protein 2
chr17_-_676348 0.12 ENST00000681510.1
ENST00000679680.1
VPS53 subunit of GARP complex
chr13_+_101489940 0.12 ENST00000376162.7
integrin subunit beta like 1
chr17_-_1649854 0.11 ENST00000301336.7
Rab interacting lysosomal protein
chr1_+_206684887 0.11 ENST00000367103.4
ENST00000294981.8
MAPK activated protein kinase 2
chr11_+_122838492 0.11 ENST00000227348.9
cytotoxic and regulatory T cell molecule
chr1_-_229434086 0.11 ENST00000366684.7
ENST00000684723.1
ENST00000366683.4
actin alpha 1, skeletal muscle
chr22_-_29388530 0.11 ENST00000357586.7
ENST00000432560.6
ENST00000405198.6
ENST00000317368.11
adaptor related protein complex 1 subunit beta 1
chr5_+_40679907 0.10 ENST00000302472.4
prostaglandin E receptor 4
chr3_+_51707059 0.10 ENST00000395052.8
glutamate metabotropic receptor 2
chr8_-_18083278 0.10 ENST00000636691.1
N-acylsphingosine amidohydrolase 1
chr1_+_32292067 0.10 ENST00000373548.8
ENST00000428704.1
histone deacetylase 1
chr11_+_130448633 0.10 ENST00000299164.4
ADAM metallopeptidase with thrombospondin type 1 motif 15
chr17_+_47896150 0.10 ENST00000642065.1
ENST00000613139.1
ENST00000637314.1
ENST00000637943.1
ENST00000376741.5
ENST00000635868.1
Sp2 transcription factor
chr19_+_3880647 0.10 ENST00000450849.7
ATCAY kinesin light chain interacting caytaxin
chr4_-_64409444 0.10 ENST00000381210.8
ENST00000507440.5
trans-2,3-enoyl-CoA reductase like
chr1_-_27490045 0.10 ENST00000536657.1
WASP family member 2
chr19_-_55157725 0.10 ENST00000344887.10
ENST00000665070.1
troponin I3, cardiac type
chr20_+_33168148 0.09 ENST00000354932.6
BPI fold containing family A member 2
chr19_-_35563653 0.09 ENST00000262623.4
ATPase H+/K+ transporting subunit alpha
chr16_+_69762309 0.09 ENST00000561780.5
ENST00000359154.7
ENST00000563659.5
WW domain containing E3 ubiquitin protein ligase 2
chr11_-_64744317 0.09 ENST00000419843.1
ENST00000394430.5
RAS guanyl releasing protein 2
chr10_-_75235917 0.09 ENST00000469299.1
ENST00000372538.8
catechol-O-methyltransferase domain containing 1
chr4_-_151015263 0.09 ENST00000510413.5
ENST00000507224.5
ENST00000651943.2
LPS responsive beige-like anchor protein
chr7_+_73830988 0.09 ENST00000340958.4
claudin 4
chr16_-_58294976 0.09 ENST00000543437.5
ENST00000569079.1
serine protease 54
chr11_-_64246907 0.09 ENST00000309318.8
protein phosphatase 1 regulatory inhibitor subunit 14B
chr3_+_159839847 0.09 ENST00000445224.6
schwannomin interacting protein 1
chr5_-_177554545 0.09 ENST00000514747.6
family with sequence similarity 193 member B
chr20_-_25623945 0.08 ENST00000304788.4
N-acetylneuraminic acid phosphatase
chr19_-_3062464 0.08 ENST00000327141.9
TLE family member 5, transcriptional modulator
chr20_-_35411963 0.08 ENST00000349714.9
ENST00000438533.5
ENST00000359226.6
ENST00000374384.6
ENST00000374385.10
ENST00000424405.5
ENST00000397554.5
ENST00000374380.6
ubiquinol-cytochrome c reductase complex assembly factor 1
chr16_-_58295019 0.08 ENST00000567164.6
ENST00000219301.8
ENST00000569727.1
serine protease 54
chr11_-_64226218 0.08 ENST00000394546.6
ENST00000541278.5
tRNA phosphotransferase 1
chr16_-_28925172 0.08 ENST00000544477.5
ENST00000357573.10
ENST00000358201.9
rabaptin, RAB GTPase binding effector protein 2
chr5_-_149379286 0.08 ENST00000261796.4
interleukin 17B
chr1_-_201171545 0.08 ENST00000367333.6
transmembrane protein 9
chr3_+_138621225 0.08 ENST00000479848.1
Fas apoptotic inhibitory molecule
chrX_-_63785510 0.08 ENST00000437457.6
ENST00000374878.5
ENST00000623517.3
Cdc42 guanine nucleotide exchange factor 9
chr16_+_6019071 0.08 ENST00000547605.5
ENST00000553186.5
RNA binding fox-1 homolog 1
chr20_+_62143729 0.07 ENST00000331758.8
ENST00000450482.5
SS18L1 subunit of BAF chromatin remodeling complex
chr19_-_4518465 0.07 ENST00000633942.1
perilipin 4
chr5_-_132011811 0.07 ENST00000379255.5
ENST00000430403.5
ENST00000357096.5
acyl-CoA synthetase long chain family member 6
chr11_-_790062 0.07 ENST00000330106.5
cell cycle exit and neuronal differentiation 1
chr8_+_144358974 0.07 ENST00000526891.2
solute carrier family 52 member 2
chr3_+_160225409 0.07 ENST00000326474.5
chromosome 3 open reading frame 80
chr1_-_225941383 0.07 ENST00000420304.6
left-right determination factor 2
chr7_-_140924699 0.07 ENST00000288602.11
ENST00000469930.2
ENST00000496384.7
B-Raf proto-oncogene, serine/threonine kinase
chr19_-_4517600 0.07 ENST00000301286.4
perilipin 4
chr10_-_70376779 0.07 ENST00000395011.5
leucine rich repeat containing 20
chr22_+_17638584 0.07 ENST00000337612.9
ENST00000418951.6
ENST00000538149.5
ENST00000543133.5
ENST00000611738.4
ENST00000616863.4
ENST00000618481.4
ENST00000317582.10
ENST00000493680.5
BCL2 like 13
chr9_-_114682172 0.07 ENST00000436752.3
testis expressed 48
chr1_-_225941212 0.07 ENST00000366820.10
left-right determination factor 2
chr1_+_159587817 0.07 ENST00000255040.3
amyloid P component, serum
chr20_+_3796288 0.07 ENST00000439880.6
ENST00000245960.10
cell division cycle 25B
chr7_+_118224654 0.07 ENST00000265224.9
ENST00000486422.1
ENST00000417525.5
ankyrin repeat domain 7
chr9_-_114682061 0.07 ENST00000612244.5
testis expressed 48
chr14_-_102509798 0.06 ENST00000560748.5
ankyrin repeat domain 9
chr12_+_10010627 0.06 ENST00000338896.11
ENST00000396502.5
C-type lectin domain family 12 member B
chr15_-_40828699 0.06 ENST00000299174.10
ENST00000427255.2
protein phosphatase 1 regulatory inhibitor subunit 14D
chr17_-_2711736 0.06 ENST00000651024.2
ENST00000576885.5
ENST00000574426.7
clustered mitochondria homolog
chr16_-_67393486 0.06 ENST00000562206.1
ENST00000393957.7
ENST00000290942.9
tubulin polymerization promoting protein family member 3
chr11_-_624924 0.06 ENST00000358353.8
ENST00000397542.7
ENST00000526077.5
ENST00000534311.1
ENST00000531088.5
cadherin related family member 5
chr3_-_113746185 0.06 ENST00000616174.1
N-alpha-acetyltransferase 50, NatE catalytic subunit
chr3_+_138621207 0.06 ENST00000464668.5
Fas apoptotic inhibitory molecule
chr22_-_50562903 0.06 ENST00000406915.4
synaptonemal complex central element protein 3
chr1_+_36224410 0.06 ENST00000469141.6
ENST00000648638.1
ENST00000354618.10
thyroid hormone receptor associated protein 3
chr11_-_64246190 0.06 ENST00000392210.6
protein phosphatase 1 regulatory inhibitor subunit 14B
chr17_-_2711633 0.06 ENST00000435359.5
clustered mitochondria homolog
chr1_+_201955496 0.06 ENST00000367287.5
translocase of inner mitochondrial membrane 17A
chr1_-_19799872 0.06 ENST00000294543.11
transmembrane and coiled-coil domains 4
chr17_-_58280928 0.06 ENST00000225275.4
myeloperoxidase
chr10_-_49762335 0.06 ENST00000419399.4
ENST00000432695.2
oxoglutarate dehydrogenase L
chr20_+_54475584 0.06 ENST00000262593.10
docking protein 5
chr11_+_68030896 0.06 ENST00000525628.1
NADH:ubiquinone oxidoreductase core subunit S8
chr7_-_151080787 0.06 ENST00000540185.5
ENST00000297532.11
Fas activated serine/threonine kinase
chr3_+_179604785 0.06 ENST00000611971.4
ENST00000493866.5
ENST00000259037.8
ENST00000472629.5
ENST00000482604.5
NADH:ubiquinone oxidoreductase subunit B5
chr1_-_17054015 0.05 ENST00000375499.8
succinate dehydrogenase complex iron sulfur subunit B
chr11_+_3855629 0.05 ENST00000526596.2
ENST00000300737.8
ENST00000616714.4
stromal interaction molecule 1
chr22_+_17638796 0.05 ENST00000355028.4
BCL2 like 13
chr6_-_87095059 0.05 ENST00000369582.6
ENST00000610310.3
ENST00000630630.2
ENST00000627148.3
ENST00000625577.1
glycoprotein hormones, alpha polypeptide
chr22_+_29307005 0.05 ENST00000406549.7
ENST00000610653.4
ENST00000621062.4
ENST00000611648.2
ENST00000618518.3
growth arrest specific 2 like 1
chr2_+_218270392 0.05 ENST00000248451.7
ENST00000273077.9
PNKD metallo-beta-lactamase domain containing
chr2_+_233712905 0.05 ENST00000373414.4
UDP glucuronosyltransferase family 1 member A5
chr7_-_151080833 0.05 ENST00000353841.6
ENST00000482571.2
Fas activated serine/threonine kinase
chr16_-_695946 0.05 ENST00000562563.1
F-box and leucine rich repeat protein 16

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 GO:0045362 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.5 1.6 GO:0046108 uridine metabolic process(GO:0046108)
0.3 0.8 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.2 0.7 GO:0097252 oligodendrocyte apoptotic process(GO:0097252)
0.2 0.6 GO:2000276 negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.2 0.5 GO:0007518 myoblast fate determination(GO:0007518)
0.1 0.4 GO:1903028 positive regulation of opsonization(GO:1903028)
0.1 0.6 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.1 0.6 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.1 0.6 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1 0.5 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.1 0.6 GO:0090210 regulation of establishment of blood-brain barrier(GO:0090210)
0.1 0.2 GO:0071962 mitotic sister chromatid cohesion, centromeric(GO:0071962)
0.1 0.5 GO:0070560 protein secretion by platelet(GO:0070560)
0.1 0.2 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.1 0.3 GO:0072011 diapedesis(GO:0050904) glomerular endothelium development(GO:0072011)
0.1 0.2 GO:0060003 copper ion export(GO:0060003)
0.1 0.2 GO:0030821 negative regulation of cyclic nucleotide catabolic process(GO:0030806) negative regulation of cAMP catabolic process(GO:0030821)
0.0 0.1 GO:0003218 cardiac left ventricle formation(GO:0003218)
0.0 0.2 GO:0021590 cerebellum maturation(GO:0021590) cerebellar cortex maturation(GO:0021699)
0.0 0.3 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.1 GO:0070676 intralumenal vesicle formation(GO:0070676)
0.0 0.1 GO:0061055 myotome development(GO:0061055)
0.0 0.3 GO:0015705 iodide transport(GO:0015705)
0.0 0.1 GO:2000417 negative regulation of eosinophil migration(GO:2000417)
0.0 0.2 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.3 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 0.1 GO:0006045 N-acetylglucosamine biosynthetic process(GO:0006045) glucosamine-containing compound biosynthetic process(GO:1901073)
0.0 0.1 GO:0045763 negative regulation of cellular amino acid metabolic process(GO:0045763)
0.0 0.9 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.3 GO:0072553 terminal button organization(GO:0072553)
0.0 0.3 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.3 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.1 GO:1903015 regulation of exo-alpha-sialidase activity(GO:1903015)
0.0 0.2 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.2 GO:0019236 response to pheromone(GO:0019236)
0.0 0.1 GO:0090131 mesenchyme migration(GO:0090131)
0.0 0.2 GO:0035524 proline transmembrane transport(GO:0035524)
0.0 0.1 GO:0002769 natural killer cell inhibitory signaling pathway(GO:0002769)
0.0 0.3 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.0 0.1 GO:0090675 intermicrovillar adhesion(GO:0090675)
0.0 0.3 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.3 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.0 0.4 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.1 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.3 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.0 GO:0051596 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0 0.2 GO:0060693 regulation of branching involved in salivary gland morphogenesis(GO:0060693)
0.0 0.1 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0 0.0 GO:1904017 cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.0 0.1 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.0 0.2 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.2 GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.0 0.5 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.3 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.3 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 0.4 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 0.1 GO:0061197 fungiform papilla morphogenesis(GO:0061197) fungiform papilla formation(GO:0061198)
0.0 0.1 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.1 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.3 GO:0048311 mitochondrion distribution(GO:0048311)
0.0 0.1 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551)
0.0 0.2 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.0 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 0.1 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.2 0.6 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753) proton-transporting ATP synthase complex(GO:0045259)
0.1 0.2 GO:0060342 photoreceptor inner segment membrane(GO:0060342)
0.1 0.3 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.1 0.2 GO:1990879 CST complex(GO:1990879)
0.0 0.6 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.5 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.2 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.2 GO:0031415 NatA complex(GO:0031415)
0.0 0.3 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.5 GO:0014731 spectrin-associated cytoskeleton(GO:0014731) platelet dense tubular network membrane(GO:0031095)
0.0 0.1 GO:1990584 cardiac Troponin complex(GO:1990584)
0.0 0.2 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.1 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.1 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.1 GO:1990745 EARP complex(GO:1990745)
0.0 0.1 GO:0071001 U4/U6 snRNP(GO:0071001)
0.0 0.2 GO:0099634 postsynaptic specialization membrane(GO:0099634)
0.0 0.1 GO:1903439 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.0 0.2 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.1 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.4 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.1 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.1 GO:0044214 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.5 1.6 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.1 0.6 GO:1904288 BAT3 complex binding(GO:1904288)
0.1 0.6 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 0.4 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.1 0.3 GO:0008431 vitamin E binding(GO:0008431)
0.1 0.3 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1 0.2 GO:0052858 peptidyl-lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0052858)
0.1 0.4 GO:0005497 androgen binding(GO:0005497)
0.1 0.2 GO:0004008 copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682)
0.1 0.2 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.0 0.1 GO:0008267 poly-glutamine tract binding(GO:0008267)
0.0 0.3 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.3 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.2 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.0 0.3 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.0 0.2 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.8 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.3 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.1 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.0 0.2 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.0 0.1 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.6 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.1 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.0 0.3 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.1 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.1 GO:0031716 calcitonin receptor activity(GO:0004948) calcitonin receptor binding(GO:0031716)
0.0 0.3 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.7 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.3 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.6 GO:0031489 myosin V binding(GO:0031489)
0.0 0.3 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.3 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.3 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.0 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 0.1 GO:0030172 troponin C binding(GO:0030172)
0.0 0.0 GO:0033142 progesterone receptor binding(GO:0033142)
0.0 0.2 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.1 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.1 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.1 GO:0051538 3 iron, 4 sulfur cluster binding(GO:0051538)
0.0 0.1 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.3 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.3 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.2 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.2 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.1 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.0 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 2.4 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.6 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.8 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.6 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.3 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.2 REACTOME OPSINS Genes involved in Opsins
0.0 0.6 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.2 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.3 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.1 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.3 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.2 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.3 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.3 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling