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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for NR6A1

Z-value: 0.79

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Transcription factors associated with NR6A1

Gene Symbol Gene ID Gene Info
ENSG00000148200.17 NR6A1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR6A1hg38_v1_chr9_-_124771238_1247712970.242.5e-01Click!

Activity profile of NR6A1 motif

Sorted Z-values of NR6A1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of NR6A1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr9_+_72577939 2.26 ENST00000645773.1
transmembrane channel like 1
chr1_+_78045956 1.58 ENST00000370759.4
GIPC PDZ domain containing family member 2
chr14_+_75605462 1.42 ENST00000539311.5
FLVCR heme transporter 2
chr1_+_61082398 1.36 ENST00000664149.1
nuclear factor I A
chr9_-_14313642 1.28 ENST00000637742.1
nuclear factor I B
chr9_-_14314067 1.27 ENST00000397575.7
nuclear factor I B
chr1_+_61082553 1.18 ENST00000403491.8
ENST00000371187.7
nuclear factor I A
chr6_+_84033717 1.15 ENST00000257776.5
melanocortin 2 receptor accessory protein 2
chr3_+_183253795 1.06 ENST00000460419.1
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
chr9_-_14314519 1.00 ENST00000397581.6
nuclear factor I B
chr9_-_14314132 0.96 ENST00000380953.6
nuclear factor I B
chr3_+_39809602 0.74 ENST00000302541.11
ENST00000396217.7
myosin VIIA and Rab interacting protein
chr4_-_158173042 0.67 ENST00000592057.1
ENST00000393807.9
golgi associated kinase 1B
chr19_+_41193198 0.67 ENST00000597754.1
ENST00000310054.9
cytochrome P450 family 2 subfamily S member 1
chr12_+_18242955 0.66 ENST00000676171.1
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma
chr22_+_22594528 0.65 ENST00000390303.3
immunoglobulin lambda variable 3-32 (non-functional)
chr4_-_185810894 0.64 ENST00000448662.6
ENST00000439049.5
ENST00000420158.5
ENST00000319471.13
sorbin and SH3 domain containing 2
chr8_-_17697654 0.63 ENST00000297488.10
microtubule associated scaffold protein 1
chr2_+_69013170 0.63 ENST00000303714.9
ANTXR cell adhesion molecule 1
chr2_+_172860038 0.62 ENST00000538974.5
ENST00000540783.5
Rap guanine nucleotide exchange factor 4
chr12_+_59664677 0.62 ENST00000548610.5
solute carrier family 16 member 7
chr5_+_141370236 0.61 ENST00000576222.2
ENST00000618934.1
protocadherin gamma subfamily B, 3
chr1_+_61082702 0.60 ENST00000485903.6
ENST00000371185.6
ENST00000371184.6
nuclear factor I A
chr2_+_236569817 0.60 ENST00000272928.4
atypical chemokine receptor 3
chr9_-_14313843 0.55 ENST00000636063.1
ENST00000380921.3
ENST00000622520.1
ENST00000380959.7
nuclear factor I B
chr3_-_149086488 0.54 ENST00000392912.6
ENST00000465259.5
ENST00000310053.10
ENST00000494055.5
helicase like transcription factor
chr1_-_161132577 0.53 ENST00000464113.1
death effector domain containing
chr14_-_75981986 0.52 ENST00000238682.8
transforming growth factor beta 3
chr11_+_111918900 0.51 ENST00000278601.6
chromosome 11 open reading frame 52
chr19_+_17406099 0.51 ENST00000634942.2
ENST00000634568.1
ENST00000600514.5
BST2 interferon stimulated positive regulator
multivesicular body subunit 12A
chr1_+_212565334 0.51 ENST00000366981.8
ENST00000366987.6
activating transcription factor 3
chr19_-_18941184 0.50 ENST00000594794.5
ENST00000392351.8
ENST00000596482.5
homer scaffold protein 3
chr6_+_30888672 0.50 ENST00000446312.5
discoidin domain receptor tyrosine kinase 1
chr19_+_7507082 0.50 ENST00000599312.1
novel transcript
chr7_-_108528155 0.50 ENST00000453085.1
patatin like phospholipase domain containing 8
chr9_+_72577788 0.49 ENST00000645208.2
transmembrane channel like 1
chr4_-_158173004 0.49 ENST00000585682.6
golgi associated kinase 1B
chr19_-_22215746 0.48 ENST00000650058.1
zinc finger protein 676
chr8_-_3409528 0.47 ENST00000335551.11
CUB and Sushi multiple domains 1
chr17_+_48723179 0.46 ENST00000422730.4
PRAC2 small nuclear protein
chr8_-_27614681 0.44 ENST00000519472.5
ENST00000523589.5
ENST00000522413.5
ENST00000523396.1
ENST00000316403.15
clusterin
chr1_+_225810057 0.44 ENST00000272167.10
ENST00000448202.5
epoxide hydrolase 1
chr1_-_161132659 0.43 ENST00000368006.8
ENST00000490843.6
ENST00000545495.5
death effector domain containing
chr17_+_68512878 0.43 ENST00000585981.5
ENST00000589480.5
ENST00000585815.5
protein kinase cAMP-dependent type I regulatory subunit alpha
chr6_-_56542802 0.43 ENST00000524186.1
dystonin
chr9_+_128455180 0.43 ENST00000497812.6
ENST00000393533.6
outer dense fiber of sperm tails 2
chr16_-_370338 0.43 ENST00000450882.1
ENST00000441883.5
ENST00000447696.5
ENST00000389675.6
mitochondrial ribosomal protein L28
chr7_+_72879349 0.42 ENST00000395270.5
POM121 transmembrane nucleoporin
chr4_+_6277309 0.42 ENST00000684087.1
ENST00000674051.1
ENST00000682059.1
ENST00000684054.1
ENST00000684700.1
ENST00000683395.1
wolframin ER transmembrane glycoprotein
chr9_-_38069220 0.40 ENST00000377707.4
SH2 domain containing adaptor protein B
chr21_+_33205279 0.40 ENST00000683941.1
interferon alpha and beta receptor subunit 2
chr9_+_72521608 0.39 ENST00000297784.10
transmembrane channel like 1
chr3_+_183253230 0.39 ENST00000326505.4
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
chr11_+_34622053 0.39 ENST00000530286.5
ENST00000533754.5
ETS homologous factor
chr6_-_31730198 0.39 ENST00000375787.6
dimethylarginine dimethylaminohydrolase 2
chr10_+_115093404 0.38 ENST00000527407.5
attractin like 1
chr12_+_12891554 0.38 ENST00000014914.6
G protein-coupled receptor class C group 5 member A
chr5_-_41213505 0.38 ENST00000337836.10
ENST00000433294.1
complement C6
chr17_-_29176752 0.38 ENST00000533112.5
myosin XVIIIA
chr16_-_75464364 0.38 ENST00000569540.5
ENST00000566594.1
transmembrane protein 170A
novel TMEM170A-CFDP1 readthrough protein
chr16_+_77722502 0.37 ENST00000564085.5
ENST00000268533.9
ENST00000568787.5
ENST00000437314.3
ENST00000563839.1
nudix hydrolase 7
chr19_-_58353482 0.37 ENST00000263100.8
alpha-1-B glycoprotein
chr11_-_35265696 0.36 ENST00000464522.2
solute carrier family 1 member 2
chr22_-_28711931 0.36 ENST00000434810.5
ENST00000456369.5
checkpoint kinase 2
chr17_-_48722510 0.36 ENST00000290294.5
PRAC1 small nuclear protein
chr1_-_154956086 0.35 ENST00000368463.8
ENST00000368460.7
ENST00000368465.5
PBX homeobox interacting protein 1
chr16_-_75464655 0.35 ENST00000569276.1
ENST00000357613.8
ENST00000561878.2
ENST00000566980.1
ENST00000567194.5
transmembrane protein 170A
novel TMEM170A-CFDP1 readthrough protein
chr19_-_14517425 0.35 ENST00000676577.1
ENST00000677204.1
ENST00000598235.2
DnaJ heat shock protein family (Hsp40) member B1
chr19_-_14518383 0.34 ENST00000254322.3
ENST00000595139.2
DnaJ heat shock protein family (Hsp40) member B1
chr8_-_129786617 0.34 ENST00000276708.9
gasdermin C
chr12_-_108826161 0.34 ENST00000546697.1
slingshot protein phosphatase 1
chr12_-_7109176 0.33 ENST00000545280.5
ENST00000543933.5
ENST00000545337.1
ENST00000266542.9
ENST00000544702.5
complement C1r subcomponent like
chr17_+_59707636 0.32 ENST00000262291.9
ENST00000587945.1
ENST00000589823.6
ENST00000592106.5
ENST00000591315.5
vacuole membrane protein 1
chr1_-_161238085 0.32 ENST00000512372.5
ENST00000437437.6
ENST00000412844.6
ENST00000428574.6
ENST00000442691.6
ENST00000505005.5
ENST00000508740.5
ENST00000367981.7
ENST00000502985.5
ENST00000504010.5
ENST00000508387.5
ENST00000511676.5
ENST00000511748.5
ENST00000511944.5
ENST00000515621.5
ENST00000367984.8
ENST00000367985.7
nuclear receptor subfamily 1 group I member 3
chr5_-_14871757 0.32 ENST00000284268.8
ANKH inorganic pyrophosphate transport regulator
chr2_-_86563470 0.30 ENST00000409225.2
charged multivesicular body protein 3
chr11_-_78341876 0.30 ENST00000340149.6
GRB2 associated binding protein 2
chr8_-_27611424 0.30 ENST00000405140.7
clusterin
chr19_-_14529193 0.30 ENST00000596853.6
ENST00000676515.1
ENST00000678338.1
ENST00000595992.6
ENST00000677848.1
ENST00000677762.1
ENST00000678009.1
ENST00000596075.2
ENST00000601533.6
ENST00000396969.8
ENST00000598692.2
ENST00000678098.1
DnaJ heat shock protein family (Hsp40) member B1
chr22_-_28712136 0.30 ENST00000464581.6
checkpoint kinase 2
chr7_+_102363874 0.30 ENST00000496391.5
PRKR interacting protein 1
chr19_-_14979848 0.30 ENST00000594383.2
solute carrier family 1 member 6
chr1_-_91404735 0.30 ENST00000455133.1
ENST00000370425.8
ENST00000427444.1
ENST00000448819.5
helicase for meiosis 1
chr7_+_37920602 0.29 ENST00000199448.9
ENST00000423717.1
ependymin related 1
chr10_-_75235917 0.29 ENST00000469299.1
ENST00000372538.8
catechol-O-methyltransferase domain containing 1
chr4_+_39182497 0.29 ENST00000509560.5
ENST00000512112.5
ENST00000399820.8
ENST00000506503.1
WD repeat domain 19
chr12_+_10213417 0.29 ENST00000546017.5
ENST00000535576.5
ENST00000539170.5
GABA type A receptor associated protein like 1
chr16_-_370514 0.28 ENST00000199706.13
mitochondrial ribosomal protein L28
chr15_+_40765620 0.28 ENST00000558467.1
GTP cyclohydrolase I feedback regulator
chr5_-_113294895 0.28 ENST00000514701.5
ENST00000302475.8
MCC regulator of WNT signaling pathway
chr2_-_25341886 0.28 ENST00000321117.10
DNA methyltransferase 3 alpha
chr19_-_42917837 0.28 ENST00000292125.6
ENST00000402603.8
ENST00000594375.1
ENST00000187910.7
pregnancy specific beta-1-glycoprotein 6
chr7_+_150824603 0.28 ENST00000493429.5
amine oxidase copper containing 1
chr15_+_76336755 0.27 ENST00000290759.9
ISL LIM homeobox 2
chr6_-_42722590 0.27 ENST00000230381.7
peripherin 2
chr19_+_40611863 0.27 ENST00000601032.5
latent transforming growth factor beta binding protein 4
chr9_-_21166660 0.26 ENST00000380225.1
interferon alpha 21
chr18_+_26133843 0.25 ENST00000415576.7
ENST00000343848.10
ENST00000308268.10
proteasome 20S subunit alpha 8
chr2_-_86563349 0.25 ENST00000409727.5
charged multivesicular body protein 3
chr5_-_94111627 0.25 ENST00000505869.5
ENST00000395965.8
ENST00000509163.5
family with sequence similarity 172 member A
chr8_-_27611325 0.24 ENST00000523500.5
clusterin
chr19_-_54947492 0.24 ENST00000592784.5
ENST00000340844.6
NLR family pyrin domain containing 7
chr12_-_91180365 0.24 ENST00000547937.5
decorin
chr1_-_202710428 0.24 ENST00000367268.5
synaptotagmin 2
chr19_-_15934521 0.24 ENST00000402119.9
cytochrome P450 family 4 subfamily F member 11
chr1_-_161238163 0.24 ENST00000367982.8
nuclear receptor subfamily 1 group I member 3
chr10_+_1056362 0.24 ENST00000263150.9
ENST00000620998.4
ENST00000381329.5
WD repeat domain 37
chr17_+_50165990 0.24 ENST00000262018.8
ENST00000344627.10
ENST00000682109.1
ENST00000504073.2
sarcoglycan alpha
chr3_-_167407837 0.23 ENST00000455345.7
zinc finger B-box domain containing
chr10_-_14572123 0.22 ENST00000378465.7
ENST00000452706.6
ENST00000622567.4
ENST00000378458.6
family with sequence similarity 107 member B
chr16_+_31355165 0.22 ENST00000562918.5
ENST00000268296.9
integrin subunit alpha X
chr10_+_122271292 0.22 ENST00000260723.6
BTB domain containing 16
chr9_-_21228222 0.22 ENST00000413767.2
interferon alpha 17
chr2_+_190343561 0.21 ENST00000322522.8
ENST00000392329.7
ENST00000430311.5
inositol polyphosphate-1-phosphatase
chr3_+_114294020 0.21 ENST00000383671.8
T cell immunoreceptor with Ig and ITIM domains
chr1_-_161238196 0.21 ENST00000367983.9
ENST00000506209.5
ENST00000367980.6
ENST00000628566.2
nuclear receptor subfamily 1 group I member 3
chrX_+_136648138 0.21 ENST00000370629.7
CD40 ligand
chr14_-_89619118 0.21 ENST00000345097.8
ENST00000555855.5
ENST00000555353.5
forkhead box N3
chr19_-_50476725 0.20 ENST00000595790.5
family with sequence similarity 71 member E1
chr19_-_8308287 0.20 ENST00000537716.6
ENST00000301458.10
CD320 molecule
chr1_-_158686700 0.20 ENST00000643759.2
spectrin alpha, erythrocytic 1
chr17_-_19042485 0.20 ENST00000395635.5
GRB2 related adaptor protein
chr17_+_34285734 0.20 ENST00000305869.4
C-C motif chemokine ligand 11
chr2_+_233388146 0.20 ENST00000409813.7
diacylglycerol kinase delta
chr19_-_42937201 0.20 ENST00000406070.7
pregnancy specific beta-1-glycoprotein 7
chr18_-_49813512 0.19 ENST00000285093.15
acetyl-CoA acyltransferase 2
chr5_-_177409535 0.19 ENST00000253496.4
coagulation factor XII
chr1_+_44746401 0.19 ENST00000372217.5
kinesin family member 2C
chr17_-_7627803 0.19 ENST00000573566.1
ENST00000269298.10
spermidine/spermine N1-acetyltransferase family member 2
chr17_-_39152571 0.19 ENST00000415163.5
ENST00000441877.5
ENST00000444911.6
plexin domain containing 1
chr6_+_28141830 0.19 ENST00000330236.7
zinc finger with KRAB and SCAN domains 8
chr19_+_8842593 0.19 ENST00000305625.2
methyl-CpG binding domain protein 3 like 1
chr19_+_49453211 0.19 ENST00000540132.5
ENST00000293350.9
ENST00000455361.6
aldehyde dehydrogenase 16 family member A1
chr11_+_113314811 0.19 ENST00000393020.5
tetratricopeptide repeat domain 12
chr14_-_19434341 0.19 ENST00000547848.5
POTE ankyrin domain family member G
chr22_+_38213530 0.19 ENST00000407965.1
MAF bZIP transcription factor F
chr7_-_75486286 0.18 ENST00000615331.5
POM121 transmembrane nucleoporin C
chr16_-_47143934 0.18 ENST00000562435.6
neuropilin and tolloid like 2
chr2_-_26244597 0.18 ENST00000492433.2
ENST00000645274.1
ENST00000380649.8
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha
chr5_+_55851378 0.18 ENST00000396836.6
ENST00000359040.10
interleukin 31 receptor A
chr2_+_134120169 0.18 ENST00000409645.5
alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase
chrX_-_119693370 0.18 ENST00000360156.11
ENST00000354228.8
ENST00000489216.5
ENST00000354416.7
ENST00000343984.5
septin 6
chr9_-_39239174 0.18 ENST00000358144.6
contactin associated protein family member 3
chr6_+_31652414 0.18 ENST00000375918.6
ENST00000375920.8
apolipoprotein M
chr22_+_41976760 0.18 ENST00000396426.7
ENST00000406029.5
septin 3
chr2_+_68774921 0.18 ENST00000497079.5
Rho GTPase activating protein 25
chr5_+_140647802 0.18 ENST00000417647.7
ENST00000507593.5
ENST00000508301.5
IK cytokine
chr4_-_98143416 0.18 ENST00000295268.4
sperm tail PG-rich repeat containing 2
chr5_+_55851349 0.17 ENST00000652347.2
interleukin 31 receptor A
chr8_-_92095627 0.17 ENST00000517919.5
ENST00000617740.4
ENST00000613302.4
ENST00000436581.6
ENST00000614812.4
ENST00000519847.5
RUNX1 partner transcriptional co-repressor 1
chr11_+_65639860 0.17 ENST00000527525.5
signal-induced proliferation-associated 1
chr19_-_22010904 0.17 ENST00000597040.1
zinc finger protein 208
chr19_-_50476838 0.17 ENST00000600100.6
family with sequence similarity 71 member E1
chrX_-_129523436 0.17 ENST00000371123.5
ENST00000371121.5
ENST00000371122.8
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
chr22_+_39994926 0.17 ENST00000333407.11
family with sequence similarity 83 member F
chr17_+_7627963 0.17 ENST00000575729.5
ENST00000340624.9
sex hormone binding globulin
chr14_-_80941687 0.17 ENST00000216517.10
centrosomal protein 128
chr1_+_107139996 0.17 ENST00000370073.6
ENST00000370074.8
netrin G1
chr9_+_121207774 0.16 ENST00000373823.7
gelsolin
chr1_+_15341744 0.16 ENST00000444385.5
forkhead associated phosphopeptide binding domain 1
chr1_+_28887072 0.16 ENST00000647103.1
ENST00000642937.2
ENST00000646189.1
ENST00000644342.1
ENST00000373800.7
ENST00000649717.1
erythrocyte membrane protein band 4.1
chr18_+_11751467 0.15 ENST00000535121.5
G protein subunit alpha L
chr22_+_45284941 0.15 ENST00000216211.9
ENST00000396082.2
uroplakin 3A
chr3_-_48717166 0.15 ENST00000413654.5
ENST00000454335.5
ENST00000440424.5
ENST00000449610.5
ENST00000443964.1
ENST00000417896.1
ENST00000413298.5
ENST00000449563.5
ENST00000443853.5
ENST00000437427.5
ENST00000446860.5
ENST00000412850.5
ENST00000424035.1
ENST00000340879.8
ENST00000431721.6
ENST00000434860.1
ENST00000328631.10
ENST00000432678.6
inositol hexakisphosphate kinase 2
chr7_+_142399860 0.15 ENST00000390364.3
T cell receptor beta variable 10-1
chr1_+_108560031 0.15 ENST00000405454.1
ENST00000370035.8
family with sequence similarity 102 member B
chr19_+_11345223 0.15 ENST00000588790.5
coiled-coil domain containing 159
chr17_+_50426242 0.15 ENST00000502667.5
acyl-CoA synthetase family member 2
chr11_-_33722403 0.15 ENST00000534312.5
novel protein
chr20_+_56412249 0.15 ENST00000679887.1
ENST00000434344.2
Cas scaffold protein family member 4
chr18_+_11751494 0.14 ENST00000269162.9
G protein subunit alpha L
chr2_-_86563382 0.14 ENST00000263856.9
charged multivesicular body protein 3
chr12_-_1918639 0.14 ENST00000382722.10
calcium voltage-gated channel auxiliary subunit alpha2delta 4
chr20_+_3071618 0.14 ENST00000217386.2
oxytocin/neurophysin I prepropeptide
chr10_+_79347491 0.14 ENST00000448165.1
peptidylprolyl isomerase F
chr13_+_111114550 0.14 ENST00000317133.9
Rho guanine nucleotide exchange factor 7
chr17_+_75093287 0.14 ENST00000538213.6
ENST00000584118.1
solute carrier family 16 member 5
chr8_-_16186270 0.14 ENST00000445506.6
macrophage scavenger receptor 1
chr11_-_128905697 0.14 ENST00000310799.9
chromosome 11 open reading frame 45
chr2_+_219597838 0.13 ENST00000456909.6
serine/threonine kinase 11 interacting protein
chr2_+_28630559 0.13 ENST00000436775.1
phospholipase B1
chr1_-_13116854 0.13 ENST00000621994.3
heterogeneous nuclear ribonucleoprotein C like 2
chr19_-_43026448 0.13 ENST00000598133.1
ENST00000403486.5
ENST00000320078.12
ENST00000306322.7
pregnancy specific beta-1-glycoprotein 11
chr10_-_49762335 0.13 ENST00000419399.4
ENST00000432695.2
oxoglutarate dehydrogenase L
chr11_-_74009077 0.13 ENST00000314032.9
ENST00000426995.2
uncoupling protein 3
chr2_+_237692290 0.13 ENST00000420665.5
ENST00000392000.4
LRR binding FLII interacting protein 1
chr7_+_6615576 0.12 ENST00000457543.4
zinc finger protein 853
chr19_+_53258292 0.12 ENST00000341702.3
vomeronasal 1 receptor 2
chr1_+_240123148 0.12 ENST00000681824.1
formin 2
chr3_-_139678011 0.12 ENST00000646611.1
ENST00000645290.1
ENST00000647257.1
nicotinamide nucleotide adenylyltransferase 3
chr7_+_94907584 0.12 ENST00000433360.6
ENST00000340694.8
ENST00000424654.5
protein phosphatase 1 regulatory subunit 9A
chr9_-_21217311 0.12 ENST00000380216.1
interferon alpha 16
chr7_-_6009072 0.12 ENST00000642456.1
ENST00000642292.1
ENST00000441476.6
PMS1 homolog 2, mismatch repair system component
chr19_-_42937098 0.12 ENST00000623675.3
ENST00000446844.3
pregnancy specific beta-1-glycoprotein 7
chr6_-_132589686 0.12 ENST00000258034.3
trace amine associated receptor 5
chr16_-_3256587 0.12 ENST00000536379.5
ENST00000541159.5
ENST00000339854.8
ENST00000219596.6
MEFV innate immuity regulator, pyrin
chr18_+_616711 0.12 ENST00000579494.1
clusterin like 1
chr16_+_30748241 0.12 ENST00000565924.5
ENST00000424889.7
phosphorylase kinase catalytic subunit gamma 2
chr3_-_139677718 0.12 ENST00000514703.5
ENST00000511444.5
ENST00000642987.1
ENST00000296202.11
ENST00000509291.5
ENST00000413939.6
ENST00000643695.2
ENST00000339837.9
ENST00000512391.5
ENST00000645507.1
nicotinamide nucleotide adenylyltransferase 3
chr19_-_15934853 0.12 ENST00000620614.4
ENST00000248041.12
cytochrome P450 family 4 subfamily F member 11

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 5.0 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.3 3.1 GO:0060005 vestibular reflex(GO:0060005)
0.2 0.7 GO:1903925 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.2 1.0 GO:1902847 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.2 0.7 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.2 0.5 GO:0003032 detection of oxygen(GO:0003032)
0.2 0.5 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.2 0.5 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.1 0.7 GO:1901202 negative regulation of extracellular matrix assembly(GO:1901202)
0.1 0.4 GO:1903892 negative regulation of ATF6-mediated unfolded protein response(GO:1903892)
0.1 0.4 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.1 0.4 GO:1903028 positive regulation of opsonization(GO:1903028)
0.1 0.4 GO:0034034 coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034)
0.1 1.5 GO:0015886 heme transport(GO:0015886)
0.1 0.3 GO:1904719 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.1 0.3 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.1 0.5 GO:0019075 virus maturation(GO:0019075)
0.1 0.4 GO:0042377 menaquinone catabolic process(GO:0042361) vitamin K catabolic process(GO:0042377)
0.1 0.3 GO:0061055 myotome development(GO:0061055)
0.1 0.3 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.1 0.6 GO:0006848 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.1 2.4 GO:0072189 ureter development(GO:0072189)
0.1 0.2 GO:0034628 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.1 1.0 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.1 0.2 GO:0042631 cellular response to water deprivation(GO:0042631)
0.1 0.2 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.1 0.5 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 0.7 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.0 0.2 GO:0051919 activation of plasma proteins involved in acute inflammatory response(GO:0002541) positive regulation of fibrinolysis(GO:0051919)
0.0 0.2 GO:0009447 putrescine catabolic process(GO:0009447)
0.0 0.1 GO:0002125 maternal aggressive behavior(GO:0002125)
0.0 0.3 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.0 0.1 GO:2000276 negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.0 0.3 GO:0071504 cellular response to heparin(GO:0071504)
0.0 0.2 GO:0034444 negative regulation of lipoprotein oxidation(GO:0034443) regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.0 0.2 GO:0031296 B cell costimulation(GO:0031296)
0.0 0.1 GO:1904049 negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.0 0.2 GO:0070778 L-aspartate transport(GO:0070778) L-aspartate transmembrane transport(GO:0089712)
0.0 0.2 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 0.2 GO:0044856 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.0 0.1 GO:1904379 tail-anchored membrane protein insertion into ER membrane(GO:0071816) protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.0 0.7 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 0.7 GO:0051292 nuclear pore complex assembly(GO:0051292) endoplasmic reticulum tubular network organization(GO:0071786)
0.0 0.1 GO:0035962 response to interleukin-13(GO:0035962)
0.0 0.4 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.4 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.2 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.0 0.4 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.1 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.0 0.5 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.2 GO:0060157 urinary bladder development(GO:0060157)
0.0 0.2 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.0 0.1 GO:0035627 ceramide transport(GO:0035627)
0.0 0.4 GO:0035745 T-helper 2 cell cytokine production(GO:0035745)
0.0 0.2 GO:0019236 response to pheromone(GO:0019236)
0.0 0.1 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.0 0.1 GO:1904862 inhibitory synapse assembly(GO:1904862)
0.0 0.3 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.1 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.0 0.1 GO:0006480 N-terminal protein amino acid methylation(GO:0006480) N-terminal peptidyl-alanine methylation(GO:0018011) N-terminal peptidyl-alanine trimethylation(GO:0018012) N-terminal peptidyl-glycine methylation(GO:0018013) N-terminal peptidyl-proline dimethylation(GO:0018016) peptidyl-alanine modification(GO:0018194) N-terminal peptidyl-proline methylation(GO:0035568) N-terminal peptidyl-serine methylation(GO:0035570) N-terminal peptidyl-serine dimethylation(GO:0035572) N-terminal peptidyl-serine trimethylation(GO:0035573)
0.0 0.4 GO:0006527 arginine catabolic process(GO:0006527)
0.0 0.4 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.1 GO:1905033 positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903762) positive regulation of ventricular cardiac muscle cell action potential(GO:1903947) positive regulation of membrane repolarization during ventricular cardiac muscle cell action potential(GO:1905026) positive regulation of membrane repolarization during cardiac muscle cell action potential(GO:1905033)
0.0 0.5 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.1 GO:0018879 biphenyl metabolic process(GO:0018879)
0.0 1.4 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.3 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 0.0 GO:0097534 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
0.0 1.1 GO:0097009 energy homeostasis(GO:0097009)
0.0 0.7 GO:0039694 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.0 0.6 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.6 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0 0.3 GO:0033008 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.0 0.2 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 0.1 GO:0001971 negative regulation of activation of membrane attack complex(GO:0001971)
0.0 0.0 GO:0030187 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0 0.2 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 0.1 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.0 0.1 GO:0097327 response to antineoplastic agent(GO:0097327)
0.0 0.1 GO:0001554 luteolysis(GO:0001554) ectopic germ cell programmed cell death(GO:0035234)
0.0 0.4 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.2 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 0.4 GO:0032733 positive regulation of interleukin-10 production(GO:0032733)
0.0 0.0 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.0 0.4 GO:0030252 growth hormone secretion(GO:0030252)
0.0 0.1 GO:0015747 urate transport(GO:0015747)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.0 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.2 3.1 GO:0032426 stereocilium tip(GO:0032426)
0.2 0.5 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.1 1.2 GO:0042583 chromaffin granule(GO:0042583)
0.1 0.4 GO:0031673 H zone(GO:0031673)
0.0 0.4 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.1 GO:0045259 mitochondrial proton-transporting ATP synthase complex(GO:0005753) proton-transporting ATP synthase complex(GO:0045259)
0.0 0.2 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.0 0.7 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.2 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.7 GO:0031045 dense core granule(GO:0031045)
0.0 0.5 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.3 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.1 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.1 GO:0044326 dendritic spine neck(GO:0044326)
0.0 0.5 GO:0001520 outer dense fiber(GO:0001520)
0.0 0.6 GO:0044615 nuclear pore central transport channel(GO:0044613) nuclear pore nuclear basket(GO:0044615)
0.0 0.2 GO:0032437 cuticular plate(GO:0032437)
0.0 0.3 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.1 GO:0070876 SOSS complex(GO:0070876)
0.0 0.1 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.1 GO:0097224 sperm connecting piece(GO:0097224)
0.0 0.4 GO:0031588 cAMP-dependent protein kinase complex(GO:0005952) nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.2 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.7 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.5 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.2 GO:0016589 NURF complex(GO:0016589)
0.0 0.7 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.1 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.1 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.3 GO:0001741 XY body(GO:0001741)
0.0 0.1 GO:0000322 storage vacuole(GO:0000322)
0.0 0.0 GO:0000939 condensed chromosome inner kinetochore(GO:0000939)
0.0 0.2 GO:0030478 actin cap(GO:0030478)
0.0 0.1 GO:1902937 inward rectifier potassium channel complex(GO:1902937)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.3 1.0 GO:0031783 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
0.2 3.1 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.2 0.7 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.2 0.6 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.2 0.8 GO:0004882 androgen receptor activity(GO:0004882)
0.1 1.5 GO:0015232 heme transporter activity(GO:0015232)
0.1 0.5 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 0.5 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 0.4 GO:0004905 type I interferon receptor activity(GO:0004905)
0.1 0.4 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.1 0.4 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.1 0.2 GO:0005174 CD40 receptor binding(GO:0005174)
0.1 0.7 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 0.2 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309)
0.1 1.3 GO:0051787 misfolded protein binding(GO:0051787)
0.1 0.2 GO:0016503 pheromone receptor activity(GO:0016503)
0.1 0.6 GO:0019958 C-X-C chemokine binding(GO:0019958)
0.1 0.3 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.5 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.4 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 0.3 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.2 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.0 0.2 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.2 GO:0052839 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.0 0.1 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.1 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.0 0.1 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.0 0.1 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.5 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.2 GO:0005497 androgen binding(GO:0005497)
0.0 0.1 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 1.0 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.5 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.1 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.0 0.2 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.4 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.2 GO:0015235 cobalamin transporter activity(GO:0015235)
0.0 0.1 GO:0032440 2-alkenal reductase [NAD(P)] activity(GO:0032440)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.2 GO:0019237 centromeric DNA binding(GO:0019237)
0.0 0.2 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.1 GO:0003883 CTP synthase activity(GO:0003883)
0.0 0.1 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.0 0.1 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0 0.4 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.2 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.0 0.1 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.6 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.5 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.6 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.1 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
0.0 0.2 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.0 0.1 GO:0098808 mRNA cap binding(GO:0098808)
0.0 0.1 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.0 0.3 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.1 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 8.7 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.4 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.2 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.3 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.1 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
0.0 0.1 GO:0032138 single base insertion or deletion binding(GO:0032138)
0.0 0.2 GO:0045159 myosin II binding(GO:0045159)
0.0 0.3 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 8.2 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.7 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.7 PID ATM PATHWAY ATM pathway
0.0 0.5 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.4 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.3 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 1.0 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.8 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.7 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.0 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.6 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.6 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.4 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.9 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.7 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.7 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.8 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 1.4 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.3 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.5 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.5 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 1.1 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.3 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.2 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.4 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 1.6 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+