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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for OLIG1

Z-value: 0.78

Motif logo

Transcription factors associated with OLIG1

Gene Symbol Gene ID Gene Info
ENSG00000184221.13 OLIG1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
OLIG1hg38_v1_chr21_+_33070133_330701490.272.0e-01Click!

Activity profile of OLIG1 motif

Sorted Z-values of OLIG1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of OLIG1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr2_+_230759918 3.73 ENST00000614925.1
calcium binding protein 39
chr8_+_85209213 3.33 ENST00000520225.1
E2F transcription factor 5
chr15_+_67067780 2.67 ENST00000679624.1
SMAD family member 3
chr2_+_108377947 2.53 ENST00000272452.7
sulfotransferase family 1C member 4
chr7_-_22193728 2.51 ENST00000620335.4
Rap guanine nucleotide exchange factor 5
chr15_+_88635626 2.39 ENST00000379224.10
interferon stimulated exonuclease gene 20
chr2_+_201129318 2.26 ENST00000417748.1
CASP8 and FADD like apoptosis regulator
chr2_+_151357583 2.23 ENST00000243347.5
TNF alpha induced protein 6
chr5_-_151080978 1.62 ENST00000520931.5
ENST00000521591.6
ENST00000520695.5
ENST00000610535.5
ENST00000518977.5
ENST00000389378.6
ENST00000610874.4
TNFAIP3 interacting protein 1
chr2_+_201129483 1.61 ENST00000440180.5
CASP8 and FADD like apoptosis regulator
chr4_-_112285892 1.57 ENST00000361717.4
TRAF interacting protein with forkhead associated domain
chr1_+_153778178 1.57 ENST00000532853.5
solute carrier family 27 member 3
chr2_+_108378176 1.52 ENST00000409309.3
sulfotransferase family 1C member 4
chr2_+_201129826 1.41 ENST00000457277.5
CASP8 and FADD like apoptosis regulator
chr1_-_7940825 1.38 ENST00000377507.8
TNF receptor superfamily member 9
chr4_+_143433491 1.31 ENST00000512843.1
GRB2 associated binding protein 1
chr3_-_108058361 1.30 ENST00000398258.7
CD47 molecule
chr11_+_60396435 1.30 ENST00000395005.6
membrane spanning 4-domains A14
chr12_+_25973748 1.28 ENST00000542865.5
Ras association domain family member 8
chr1_+_169795022 1.17 ENST00000359326.9
ENST00000496973.5
chromosome 1 open reading frame 112
chr1_+_100345018 1.16 ENST00000635056.2
ENST00000647005.1
cell division cycle 14A
chr6_+_30571393 1.15 ENST00000376545.7
ENST00000441867.6
ENST00000468958.1
ENST00000326195.13
ATP binding cassette subfamily F member 1
chr6_-_56542802 1.02 ENST00000524186.1
dystonin
chr12_+_133080875 1.02 ENST00000412146.6
ENST00000544426.5
ENST00000355557.7
ENST00000319849.7
ENST00000440550.6
zinc finger protein 140
chr19_-_1021114 0.98 ENST00000333175.9
ENST00000356663.8
transmembrane protein 259
chr17_-_75878542 0.96 ENST00000254816.6
tripartite motif containing 47
chr11_+_60396451 0.95 ENST00000300187.11
ENST00000526375.5
ENST00000531783.5
membrane spanning 4-domains A14
chr1_+_159439722 0.92 ENST00000641630.1
ENST00000423932.6
olfactory receptor family 10 subfamily J member 1
chr17_-_181640 0.91 ENST00000613549.3
double C2 domain beta
chr18_+_24155938 0.86 ENST00000582229.1
calcium binding tyrosine phosphorylation regulated
chr4_+_8229170 0.85 ENST00000511002.6
SH3 domain and tetratricopeptide repeats 1
chr1_-_23980345 0.81 ENST00000484146.6
serine and arginine rich splicing factor 10
chr6_+_135181361 0.77 ENST00000527615.5
ENST00000420123.6
ENST00000525369.5
ENST00000528774.5
ENST00000533624.5
ENST00000534044.5
ENST00000534121.5
MYB proto-oncogene, transcription factor
chr18_-_31760864 0.76 ENST00000269205.7
ENST00000672005.1
solute carrier family 25 member 52
chr1_+_50103903 0.74 ENST00000371827.5
ELAV like RNA binding protein 4
chr9_+_107306459 0.67 ENST00000457811.1
RAD23 homolog B, nucleotide excision repair protein
chr5_+_136160986 0.67 ENST00000507637.1
SMAD family member 5
chr12_-_95548213 0.67 ENST00000537435.2
ubiquitin specific peptidase 44
chr1_+_206635573 0.66 ENST00000367108.7
dual specificity tyrosine phosphorylation regulated kinase 3
chr5_-_11588842 0.65 ENST00000503622.5
catenin delta 2
chr11_-_57427078 0.61 ENST00000528187.5
ENST00000524863.5
ENST00000533051.5
ENST00000529494.5
ENST00000395124.6
ENST00000533524.5
ENST00000533245.5
ENST00000530316.5
solute carrier family 43 member 3
chr15_-_58014097 0.60 ENST00000559517.5
aldehyde dehydrogenase 1 family member A2
chr6_+_69232406 0.59 ENST00000238918.12
adhesion G protein-coupled receptor B3
chr5_-_172006567 0.58 ENST00000517395.6
ENST00000265094.9
ENST00000393802.6
F-box and WD repeat domain containing 11
chrX_-_155334580 0.54 ENST00000369449.7
ENST00000321926.4
chloride intracellular channel 2
chr16_+_71808439 0.53 ENST00000683775.1
ataxin 1 like
chr3_-_195583931 0.52 ENST00000343267.8
ENST00000421243.5
ENST00000453131.1
apolipoprotein D
chr9_-_21368962 0.50 ENST00000610660.1
interferon alpha 13
chr1_+_148748774 0.50 ENST00000322209.5
nudix hydrolase 4B
chr1_-_186375671 0.50 ENST00000451586.1
translocated promoter region, nuclear basket protein
chr3_+_75664327 0.49 ENST00000308062.8
ENST00000464571.1
FSHD region gene 2 family member C
chr22_+_25742141 0.49 ENST00000536101.5
ENST00000335473.12
ENST00000407587.6
myosin XVIIIB
chr5_-_172006817 0.47 ENST00000296933.10
F-box and WD repeat domain containing 11
chr20_+_33217325 0.47 ENST00000375452.3
ENST00000375454.8
BPI fold containing family A member 3
chr5_+_141373878 0.45 ENST00000517434.3
ENST00000610583.1
protocadherin gamma subfamily A, 6
chr13_+_38349822 0.44 ENST00000379649.5
ENST00000239878.9
ubiquitin fold modifier 1
chr12_-_14938508 0.43 ENST00000266397.7
endoplasmic reticulum protein 27
chr6_+_31586124 0.43 ENST00000418507.6
ENST00000376096.5
ENST00000376099.5
ENST00000376110.7
leukocyte specific transcript 1
chr5_-_35938572 0.43 ENST00000651391.1
ENST00000397366.5
ENST00000513623.5
ENST00000514524.2
ENST00000397367.6
calcyphosine like
chr7_+_4682252 0.43 ENST00000328914.5
forkhead box K1
chr16_-_69351778 0.42 ENST00000288025.4
transmembrane p24 trafficking protein 6
chr10_-_59753388 0.42 ENST00000430431.5
myoregulin
chr3_-_49429252 0.41 ENST00000615713.4
nicolin 1
chr3_+_12557050 0.41 ENST00000411987.5
ENST00000170447.12
ENST00000448482.1
ENST00000677142.1
makorin ring finger protein 2
chr17_-_676348 0.41 ENST00000681510.1
ENST00000679680.1
VPS53 subunit of GARP complex
chr2_+_197453423 0.41 ENST00000263960.6
coenzyme Q10B
chr5_-_11589019 0.39 ENST00000511377.5
catenin delta 2
chr18_-_58629084 0.38 ENST00000361673.4
alpha kinase 2
chr11_+_55883297 0.37 ENST00000449290.6
tripartite motif-containing 51
chr1_-_23980278 0.37 ENST00000374453.7
ENST00000453840.7
serine and arginine rich splicing factor 10
chr4_-_75990919 0.36 ENST00000395711.8
ENST00000356260.10
SDA1 domain containing 1
chr22_+_43923755 0.36 ENST00000423180.2
ENST00000216180.8
patatin like phospholipase domain containing 3
chr11_-_72112068 0.36 ENST00000537644.5
ENST00000538919.5
ENST00000539395.1
ENST00000542531.5
anaphase promoting complex subunit 15
chr6_+_10528326 0.35 ENST00000379597.7
glucosaminyl (N-acetyl) transferase 2 (I blood group)
chr1_+_110339462 0.35 ENST00000617047.1
RNA binding motif protein 15
chr1_+_206635521 0.35 ENST00000367109.8
dual specificity tyrosine phosphorylation regulated kinase 3
chr7_+_107891135 0.35 ENST00000639772.1
ENST00000440410.5
ENST00000437604.6
ENST00000205402.10
dihydrolipoamide dehydrogenase
chr19_+_57584156 0.34 ENST00000307468.4
ENST00000599456.1
zinc finger protein interacting with K protein 1
chr6_+_31586269 0.33 ENST00000438075.7
leukocyte specific transcript 1
chr1_+_152908538 0.33 ENST00000368764.4
involucrin
chr3_-_49429304 0.33 ENST00000636166.1
ENST00000273598.8
ENST00000436744.2
novel protein
nicolin 1
chr17_-_17582417 0.33 ENST00000395783.5
phosphatidylethanolamine N-methyltransferase
chr8_-_23457677 0.32 ENST00000356206.10
ENST00000417069.6
ectonucleoside triphosphate diphosphohydrolase 4
chr18_+_13277351 0.32 ENST00000679091.1
low density lipoprotein receptor class A domain containing 4
chr2_+_89947508 0.32 ENST00000491977.1
immunoglobulin kappa variable 2D-29
chr11_-_48983826 0.32 ENST00000649162.1
tripartite motif-containing 51G, pseudogene
chr5_+_141359970 0.31 ENST00000522605.2
ENST00000622527.1
protocadherin gamma subfamily B, 2
chr5_+_168291599 0.31 ENST00000265293.9
WW and C2 domain containing 1
chr16_-_71809049 0.31 ENST00000569748.5
ENST00000570017.1
ENST00000393512.7
adaptor related protein complex 1 subunit gamma 1
chr12_-_130839230 0.31 ENST00000392373.7
ENST00000261653.10
syntaxin 2
chr16_-_30894264 0.31 ENST00000380317.8
BAF chromatin remodeling complex subunit BCL7C
chr19_+_39971155 0.30 ENST00000157812.7
ENST00000455878.2
proteasome 26S subunit, ATPase 4
chr2_+_158968608 0.30 ENST00000263635.8
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
chr3_-_53882142 0.30 ENST00000335754.8
actin related protein 8
chr6_-_26271815 0.30 ENST00000614378.1
H3 clustered histone 8
chr6_+_12716801 0.29 ENST00000674595.1
phosphatase and actin regulator 1
chr12_+_54000096 0.29 ENST00000303450.5
homeobox C9
chr10_+_27504328 0.29 ENST00000375802.7
RAB18, member RAS oncogene family
chr14_-_60165293 0.29 ENST00000554101.5
ENST00000557137.1
dehydrogenase/reductase 7
chr14_+_88005128 0.29 ENST00000267549.5
G protein-coupled receptor 65
chr14_-_106875069 0.28 ENST00000390639.2
immunoglobulin heavy variable 7-81 (non-functional)
chr10_+_27532521 0.28 ENST00000683924.1
RAB18, member RAS oncogene family
chr1_-_19484635 0.28 ENST00000433834.5
capping actin protein of muscle Z-line subunit beta
chr7_+_111091119 0.27 ENST00000308478.10
leucine rich repeat neuronal 3
chr15_+_51377247 0.27 ENST00000396399.6
gliomedin
chr9_-_129642094 0.27 ENST00000277459.8
ENST00000277458.5
ENST00000450050.6
ankyrin repeat and SOCS box containing 6
chr11_+_65833944 0.27 ENST00000308342.7
sorting nexin 32
chr12_+_21131187 0.26 ENST00000256958.3
solute carrier organic anion transporter family member 1B1
chr1_-_52366124 0.26 ENST00000371586.6
ENST00000284376.8
coiled-coil and C2 domain containing 1B
chr8_+_22057857 0.26 ENST00000517305.4
ENST00000265800.9
ENST00000517418.5
dematin actin binding protein
chr10_-_72354895 0.26 ENST00000444643.8
ENST00000338820.7
ENST00000394903.6
DnaJ heat shock protein family (Hsp40) member B12
chr6_+_11093753 0.25 ENST00000416247.4
small integral membrane protein 13
chr9_-_115118145 0.25 ENST00000350763.9
tenascin C
chr6_-_31958852 0.25 ENST00000375425.9
ENST00000426722.5
negative elongation factor complex member E
chr17_-_41382298 0.25 ENST00000394001.3
keratin 34
chr1_+_110339323 0.25 ENST00000602849.1
ENST00000487146.8
ENST00000618772.4
ENST00000369784.9
ENST00000650953.2
ENST00000652342.2
ENST00000654015.1
RNA binding motif protein 15
chr12_+_9971402 0.25 ENST00000304361.9
ENST00000396507.7
ENST00000434319.6
C-type lectin domain family 12 member A
chr9_+_5450503 0.25 ENST00000381573.8
ENST00000381577.4
CD274 molecule
chr7_+_111091006 0.25 ENST00000451085.5
ENST00000422987.3
ENST00000421101.1
leucine rich repeat neuronal 3
chr12_-_10849464 0.25 ENST00000544994.5
ENST00000228811.8
ENST00000540107.2
proline rich 4
chr4_+_73853290 0.25 ENST00000226524.4
platelet factor 4 variant 1
chr6_-_31958935 0.25 ENST00000441998.5
ENST00000444811.6
ENST00000375429.8
negative elongation factor complex member E
chr20_+_49812697 0.25 ENST00000417961.5
solute carrier family 9 member A8
chr5_+_147878703 0.24 ENST00000296694.5
secretoglobin family 3A member 2
chr12_+_6789508 0.24 ENST00000011653.9
ENST00000541982.5
ENST00000539492.1
CD4 molecule
chr4_-_41214602 0.24 ENST00000508676.5
ENST00000506352.5
ENST00000295974.12
amyloid beta precursor protein binding family B member 2
chr16_+_31108294 0.24 ENST00000287507.7
ENST00000394950.7
ENST00000219794.11
ENST00000561755.1
branched chain keto acid dehydrogenase kinase
chr11_-_33722403 0.24 ENST00000534312.5
novel protein
chr15_+_74173693 0.24 ENST00000249842.8
immunoglobulin superfamily containing leucine rich repeat
chr22_-_30557586 0.24 ENST00000338911.6
ENST00000453479.1
galactose-3-O-sulfotransferase 1
chr6_-_46954922 0.24 ENST00000265417.7
adhesion G protein-coupled receptor F5
chr10_-_67838173 0.24 ENST00000225171.7
DnaJ heat shock protein family (Hsp40) member C12
chr16_+_21704963 0.23 ENST00000388957.3
otoancorin
chr11_+_120236635 0.23 ENST00000260264.8
POU class 2 homeobox 3
chr4_-_158173042 0.23 ENST00000592057.1
ENST00000393807.9
golgi associated kinase 1B
chr3_+_9797651 0.23 ENST00000453882.1
ARPC4-TTLL3 readthrough
chr7_-_93226449 0.23 ENST00000394468.7
ENST00000453812.2
HEPACAM family member 2
chr19_+_38899680 0.22 ENST00000576510.5
ENST00000392079.7
NFKB inhibitor beta
chr15_-_48963912 0.22 ENST00000332408.9
SHC adaptor protein 4
chr11_-_59845496 0.22 ENST00000257248.3
cobalamin binding intrinsic factor
chr6_-_28923932 0.21 ENST00000377199.4
ENST00000377194.7
tripartite motif containing 27
chr2_+_135741814 0.21 ENST00000272638.14
UBX domain protein 4
chr19_+_57363469 0.21 ENST00000282282.4
ENST00000543226.2
ENST00000596755.1
ENST00000597658.1
zinc finger protein 547
trafficking protein particle complex 2B
novel protein
chr14_+_24070837 0.21 ENST00000537691.5
ENST00000397016.6
ENST00000560356.5
ENST00000558450.5
copine 6
chr8_+_69466617 0.21 ENST00000525061.5
ENST00000260128.8
ENST00000458141.6
sulfatase 1
chr14_+_69398683 0.21 ENST00000556605.5
ENST00000031146.8
ENST00000336643.10
solute carrier family 39 member 9
chr2_-_97094882 0.20 ENST00000414820.6
ENST00000272610.3
fumarylacetoacetate hydrolase domain containing 2B
chr16_-_20352707 0.20 ENST00000396134.6
ENST00000573567.5
ENST00000570757.5
ENST00000396138.9
ENST00000571174.5
ENST00000576688.2
uromodulin
chr7_-_36985060 0.20 ENST00000396040.6
engulfment and cell motility 1
chr16_-_71808803 0.19 ENST00000563104.5
ENST00000569975.5
ENST00000565412.5
ENST00000567583.1
ENST00000299980.9
adaptor related protein complex 1 subunit gamma 1
chr4_+_69931066 0.19 ENST00000246891.9
casein alpha s1
chr10_-_92497727 0.19 ENST00000496903.5
ENST00000678824.1
ENST00000371581.9
insulin degrading enzyme
chr1_-_23980308 0.19 ENST00000374452.9
ENST00000492112.3
ENST00000343255.9
ENST00000344989.10
serine and arginine rich splicing factor 10
chr7_+_114922854 0.19 ENST00000423503.1
ENST00000427207.5
MyoD family inhibitor domain containing
chr15_-_89211803 0.19 ENST00000563254.1
retinaldehyde binding protein 1
chr16_+_11965193 0.19 ENST00000053243.6
ENST00000396495.3
TNF receptor superfamily member 17
chr3_-_197184131 0.18 ENST00000452595.5
discs large MAGUK scaffold protein 1
chr12_-_108320635 0.18 ENST00000412676.5
ENST00000550573.5
chemerin chemokine-like receptor 1
chr3_-_197183849 0.17 ENST00000443183.5
discs large MAGUK scaffold protein 1
chr14_+_37622065 0.17 ENST00000553443.5
tetratricopeptide repeat domain 6
chr10_+_26438317 0.17 ENST00000376236.9
amyloid beta precursor protein binding family B member 1 interacting protein
chr14_-_69398276 0.17 ENST00000557016.6
ENST00000555373.1
ERH mRNA splicing and mitosis factor
chr5_+_141408032 0.17 ENST00000520790.1
protocadherin gamma subfamily B, 6
chr1_+_156212982 0.17 ENST00000490491.5
ENST00000368276.8
ENST00000567140.3
ENST00000320139.5
ENST00000368279.7
ENST00000368273.8
ENST00000368277.3
PMF1-BGLAP readthrough
polyamine modulated factor 1
chr2_-_162152239 0.16 ENST00000418842.7
glucagon
chr9_+_105662457 0.16 ENST00000334077.6
TAL bHLH transcription factor 2
chr12_-_16608073 0.16 ENST00000441439.6
LIM domain only 3
chr4_-_110641920 0.15 ENST00000354925.6
ENST00000511990.1
ENST00000613094.4
ENST00000614423.4
ENST00000616641.4
ENST00000511837.5
paired like homeodomain 2
chr12_-_16608183 0.15 ENST00000354662.5
ENST00000538051.5
LIM domain only 3
chr1_+_147242654 0.15 ENST00000652587.1
ENST00000361293.10
ENST00000369258.8
ENST00000369259.4
ENST00000650714.1
ENST00000639534.1
chromodomain helicase DNA binding protein 1 like
chr17_+_47253817 0.15 ENST00000559488.7
ENST00000571680.1
integrin subunit beta 3
chr1_+_180928133 0.15 ENST00000367587.1
KIAA1614
chrX_+_65667645 0.15 ENST00000360270.7
moesin
chr14_-_105242605 0.15 ENST00000549655.5
BRF1 RNA polymerase III transcription initiation factor subunit
chr2_+_10368645 0.14 ENST00000613496.4
hippocalcin like 1
chr12_-_91179517 0.14 ENST00000551354.1
decorin
chr19_+_44259903 0.14 ENST00000588489.5
ENST00000391958.6
zinc finger protein 233
chr1_+_103750406 0.14 ENST00000370079.3
amylase alpha 1C
chr16_-_4846196 0.14 ENST00000589389.5
glyoxylate reductase 1 homolog
chr7_+_140696665 0.14 ENST00000476279.5
ENST00000461457.1
ENST00000465506.5
NADH:ubiquinone oxidoreductase subunit B2
chr5_+_108924585 0.14 ENST00000618353.1
FER tyrosine kinase
chrX_+_55623400 0.13 ENST00000339140.5
forkhead box R2
chr11_+_18599782 0.13 ENST00000634992.1
ENST00000635674.1
ENST00000511927.2
SPTY2D1 opposite strand
chr10_-_67838019 0.13 ENST00000483798.6
DnaJ heat shock protein family (Hsp40) member C12
chr13_+_49628489 0.13 ENST00000282026.2
ADP ribosylation factor like GTPase 11
chrX_-_13319952 0.13 ENST00000622204.1
ENST00000380622.5
ataxin 3 like
chr16_+_1966820 0.13 ENST00000569210.6
ENST00000569714.6
ring finger protein 151
chr1_+_186375813 0.12 ENST00000419367.8
ENST00000287859.11
ENST00000367470.8
odr-4 GPCR localization factor homolog
chr16_-_370338 0.12 ENST00000450882.1
ENST00000441883.5
ENST00000447696.5
ENST00000389675.6
mitochondrial ribosomal protein L28
chr2_-_79086847 0.12 ENST00000454188.5
regenerating family member 1 beta
chr11_+_65638085 0.12 ENST00000534313.6
ENST00000533361.1
ENST00000526137.1
signal-induced proliferation-associated 1
chr7_-_2815226 0.12 ENST00000447791.1
ENST00000407904.7
G protein subunit alpha 12
chr17_+_41689862 0.12 ENST00000586699.1
eukaryotic translation initiation factor 1
chr9_-_127937800 0.12 ENST00000373110.4
ENST00000314392.13
dolichyl-phosphate mannosyltransferase subunit 2, regulatory
chr17_+_68035636 0.12 ENST00000676857.1
ENST00000676594.1
ENST00000678388.1
karyopherin subunit alpha 2
chr11_+_124183219 0.12 ENST00000641351.2
olfactory receptor family 10 subfamily D member 3
chr6_+_12716760 0.11 ENST00000332995.12
phosphatase and actin regulator 1
chr4_+_145481845 0.11 ENST00000302085.9
ENST00000512019.1
SMAD family member 1
chr3_-_121660892 0.11 ENST00000428394.6
ENST00000314583.8
hematopoietic cell-specific Lyn substrate 1
chr3_+_119579577 0.11 ENST00000478927.5
ADP-ribosylarginine hydrolase

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.7 GO:2000687 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.6 2.4 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.5 1.6 GO:0085032 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.5 5.3 GO:1903943 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.4 2.7 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.3 1.3 GO:0034334 adherens junction maintenance(GO:0034334)
0.3 0.8 GO:1990922 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.2 1.4 GO:2001180 negative regulation of interleukin-10 secretion(GO:2001180)
0.2 0.5 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.2 0.5 GO:0043321 regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
0.2 1.0 GO:0035617 stress granule disassembly(GO:0035617)
0.2 0.5 GO:0031453 regulation of heterochromatin assembly(GO:0031445) positive regulation of heterochromatin assembly(GO:0031453)
0.2 4.1 GO:0006068 ethanol catabolic process(GO:0006068)
0.1 0.6 GO:0099558 maintenance of synapse structure(GO:0099558)
0.1 0.3 GO:0009106 lipoate metabolic process(GO:0009106)
0.1 0.7 GO:0001880 Mullerian duct regression(GO:0001880)
0.1 1.4 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.1 0.3 GO:0060739 mesenchymal-epithelial cell signaling involved in prostate gland development(GO:0060739)
0.1 0.9 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.1 0.3 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.1 0.4 GO:1902081 regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
0.1 0.3 GO:1903575 cornified envelope assembly(GO:1903575)
0.1 0.2 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 0.6 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.1 0.2 GO:0072233 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.1 2.2 GO:0030728 ovulation(GO:0030728)
0.1 0.4 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.1 1.1 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.1 0.1 GO:0071569 protein ufmylation(GO:0071569)
0.1 1.3 GO:0008228 opsonization(GO:0008228)
0.1 1.0 GO:0008090 retrograde axonal transport(GO:0008090)
0.1 1.0 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.1 0.2 GO:0060578 subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) superior vena cava morphogenesis(GO:0060578)
0.1 0.4 GO:0036438 maintenance of lens transparency(GO:0036438)
0.1 0.2 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0 0.5 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.0 0.2 GO:1901143 insulin catabolic process(GO:1901143)
0.0 0.2 GO:0018094 protein polyglycylation(GO:0018094)
0.0 0.3 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 0.6 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.2 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.0 0.2 GO:0035723 interleukin-15-mediated signaling pathway(GO:0035723) cellular response to interleukin-15(GO:0071350)
0.0 0.3 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.0 1.3 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.0 1.0 GO:1904294 positive regulation of ERAD pathway(GO:1904294)
0.0 0.3 GO:0070560 protein secretion by platelet(GO:0070560)
0.0 1.1 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.0 0.3 GO:0006686 sphingomyelin biosynthetic process(GO:0006686) positive regulation of lipoprotein metabolic process(GO:0050747)
0.0 0.9 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.2 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.0 0.1 GO:0018874 benzoate metabolic process(GO:0018874)
0.0 0.1 GO:0036215 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109) diapedesis(GO:0050904)
0.0 0.5 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.0 0.2 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.0 0.2 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.0 0.4 GO:0043622 cortical microtubule organization(GO:0043622) establishment of centrosome localization(GO:0051660)
0.0 0.1 GO:0042631 cellular response to water deprivation(GO:0042631)
0.0 0.1 GO:0022614 membrane to membrane docking(GO:0022614)
0.0 0.5 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.0 0.9 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.4 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.0 0.1 GO:0097325 melanocyte proliferation(GO:0097325)
0.0 0.2 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.3 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.3 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
0.0 0.1 GO:1990918 double-strand break repair involved in meiotic recombination(GO:1990918)
0.0 0.1 GO:1903755 regulation of SUMO transferase activity(GO:1903182) positive regulation of SUMO transferase activity(GO:1903755)
0.0 0.1 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.0 0.3 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.8 GO:0000717 nucleotide-excision repair, DNA duplex unwinding(GO:0000717)
0.0 0.2 GO:0071073 surfactant homeostasis(GO:0043129) positive regulation of phospholipid biosynthetic process(GO:0071073)
0.0 0.1 GO:0019348 dolichol metabolic process(GO:0019348)
0.0 0.3 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.3 GO:0010990 regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.3 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.1 GO:0042732 D-xylose metabolic process(GO:0042732)
0.0 0.1 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.2 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.2 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.4 GO:1901663 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.2 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.1 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.1 GO:0009304 transcription initiation from RNA polymerase III promoter(GO:0006384) tRNA transcription(GO:0009304)
0.0 0.1 GO:0046462 monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.0 0.2 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 0.1 GO:0009048 dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.2 GO:0016540 protein autoprocessing(GO:0016540)
0.0 0.2 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747) negative regulation of cellular response to vascular endothelial growth factor stimulus(GO:1902548)
0.0 0.1 GO:0060005 vestibular reflex(GO:0060005)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.7 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.2 5.3 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.2 0.9 GO:0097229 sperm end piece(GO:0097229)
0.2 1.0 GO:0031673 H zone(GO:0031673)
0.1 0.7 GO:0071942 XPC complex(GO:0071942)
0.1 0.3 GO:0043159 acrosomal matrix(GO:0043159)
0.1 1.2 GO:0060091 kinocilium(GO:0060091)
0.1 0.5 GO:0032021 NELF complex(GO:0032021)
0.1 0.2 GO:0097637 intrinsic component of autophagosome membrane(GO:0097636) integral component of autophagosome membrane(GO:0097637)
0.1 0.8 GO:0071141 SMAD protein complex(GO:0071141)
0.1 0.4 GO:1990745 EARP complex(GO:1990745)
0.1 0.2 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.6 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.1 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0 0.1 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.0 0.2 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.2 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.0 2.4 GO:0015030 Cajal body(GO:0015030)
0.0 0.3 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.2 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 0.6 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 5.9 GO:0101002 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.0 0.1 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.5 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.1 GO:1990356 sumoylated E2 ligase complex(GO:1990356)
0.0 0.4 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.3 GO:0071203 WASH complex(GO:0071203)
0.0 3.5 GO:0001650 fibrillar center(GO:0001650)
0.0 0.6 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 1.2 GO:0031201 SNARE complex(GO:0031201)
0.0 0.3 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 1.1 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.2 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.2 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 1.0 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.2 GO:0034709 methylosome(GO:0034709)
0.0 0.3 GO:0014731 spectrin-associated cytoskeleton(GO:0014731) platelet dense tubular network membrane(GO:0031095)
0.0 0.2 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 GO:0008859 exoribonuclease II activity(GO:0008859)
0.4 2.7 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.2 4.1 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.2 1.4 GO:0050733 RS domain binding(GO:0050733)
0.2 5.3 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.2 2.4 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 0.3 GO:0004608 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.1 1.3 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.1 0.8 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.1 3.7 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 1.6 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1 0.2 GO:0031626 beta-endorphin binding(GO:0031626)
0.1 0.8 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 2.2 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.4 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.1 0.4 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.2 GO:0070735 protein-glycine ligase activity(GO:0070735)
0.0 2.2 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.3 GO:0004738 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.0 0.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.4 GO:0048039 ubiquinone binding(GO:0048039)
0.0 1.4 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.1 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0 0.6 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 0.2 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 0.1 GO:0001026 TFIIIB-type transcription factor activity(GO:0001026)
0.0 0.2 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.3 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.3 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.3 GO:0045545 syndecan binding(GO:0045545)
0.0 0.2 GO:0045134 uridine-diphosphatase activity(GO:0045134)
0.0 0.4 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.2 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.1 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
0.0 0.1 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
0.0 0.2 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.1 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.0 1.4 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.0 0.7 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.2 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.5 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.1 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.5 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.0 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.0 0.3 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 1.0 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.2 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.2 GO:0019864 IgG binding(GO:0019864)
0.0 0.1 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.2 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.8 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.1 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.9 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 1.3 GO:0008135 translation factor activity, RNA binding(GO:0008135)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.3 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 2.2 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.8 PID ALK2 PATHWAY ALK2 signaling events
0.0 3.2 PID LKB1 PATHWAY LKB1 signaling events
0.0 1.8 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 3.3 PID E2F PATHWAY E2F transcription factor network
0.0 1.7 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 1.1 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.8 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.3 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.2 4.1 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 3.7 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.1 6.0 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 1.3 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 1.3 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.2 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 1.2 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.5 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.4 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 2.2 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.3 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.7 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.8 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 1.5 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 0.3 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.4 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.5 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.3 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins