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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for OVOL1

Z-value: 0.22

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Transcription factors associated with OVOL1

Gene Symbol Gene ID Gene Info
OVOL1
ENSG00000172818.10 OVOL1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
OVOL1hg38_v1_chr11_+_65787056_657870750.203.3e-01Click!

Activity profile of OVOL1 motif

Sorted Z-values of OVOL1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of OVOL1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr6_-_83709382 0.54 ENST00000520302.5
ENST00000520213.5
ENST00000439399.6
SNAP91
synaptosome associated protein 91
chrX_-_117973717 0.52 ENST00000262820.7
KLHL13
kelch like family member 13
chrX_-_117973579 0.48 ENST00000371878.5
KLHL13
kelch like family member 13
chr3_-_165837412 0.38 ENST00000479451.5
ENST00000488954.1
ENST00000264381.8
BCHE
butyrylcholinesterase
chr11_+_123430259 0.35 ENST00000533341.3
ENST00000635736.2
GRAMD1B
GRAM domain containing 1B
chr2_-_182522703 0.25 ENST00000410103.1
PDE1A
phosphodiesterase 1A
chr4_+_75556048 0.18 ENST00000616557.1
ENST00000435974.2
ENST00000311623.9
ODAPH
odontogenesis associated phosphoprotein
chr5_+_161850597 0.16 ENST00000634335.1
ENST00000635880.1
GABRA1
gamma-aminobutyric acid type A receptor subunit alpha1
chr15_-_64093746 0.14 ENST00000557835.5
ENST00000380290.7
ENST00000300030.8
ENST00000559950.1
CIAO2A
cytosolic iron-sulfur assembly component 2A
chr10_+_47322450 0.14 ENST00000581492.3
GDF2
growth differentiation factor 2
chr12_-_56741535 0.14 ENST00000647707.1
ENSG00000285625.1
novel protein
chr15_+_75843438 0.13 ENST00000267938.9
UBE2Q2
ubiquitin conjugating enzyme E2 Q2
chr15_+_75843307 0.12 ENST00000569423.5
UBE2Q2
ubiquitin conjugating enzyme E2 Q2
chr19_+_6772699 0.12 ENST00000602142.6
ENST00000304076.6
ENST00000596764.5
VAV1
vav guanine nucleotide exchange factor 1
chr15_+_75043263 0.11 ENST00000563393.1
PPCDC
phosphopantothenoylcysteine decarboxylase
chr2_-_182522556 0.10 ENST00000435564.5
PDE1A
phosphodiesterase 1A
chr5_-_16508812 0.09 ENST00000683414.1
RETREG1
reticulophagy regulator 1
chr20_+_56248732 0.08 ENST00000243911.2
MC3R
melanocortin 3 receptor
chr18_+_54269493 0.08 ENST00000579534.6
ENST00000406285.7
ENST00000577612.5
ENST00000579434.5
ENST00000583136.5
POLI
DNA polymerase iota
chr5_-_16508858 0.07 ENST00000684456.1
RETREG1
reticulophagy regulator 1
chr5_-_16508951 0.07 ENST00000682628.1
RETREG1
reticulophagy regulator 1
chr5_+_141359970 0.06 ENST00000522605.2
ENST00000622527.1
PCDHGB2
protocadherin gamma subfamily B, 2
chr17_-_7242156 0.05 ENST00000571129.5
ENST00000571253.1
ENST00000573928.1
ENST00000302386.10
GABARAP
GABA type A receptor-associated protein
chr5_-_16508990 0.04 ENST00000399793.6
RETREG1
reticulophagy regulator 1
chr4_-_67754335 0.03 ENST00000420975.2
ENST00000226413.5
GNRHR
gonadotropin releasing hormone receptor
chr19_+_37371152 0.03 ENST00000483919.5
ENST00000588911.5
ENST00000587349.1
ZNF527
zinc finger protein 527
chr5_-_16508788 0.02 ENST00000682142.1
RETREG1
reticulophagy regulator 1
chr3_+_57890011 0.02 ENST00000494088.6
ENST00000438794.5
SLMAP
sarcolemma associated protein
chr5_+_140882116 0.01 ENST00000289272.3
ENST00000409494.5
ENST00000617769.1
PCDHA13
protocadherin alpha 13

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0014016 neuroblast differentiation(GO:0014016)
0.0 0.3 GO:0061709 reticulophagy(GO:0061709)
0.0 0.5 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.3 GO:0046069 cGMP catabolic process(GO:0046069)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 1.0 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0003990 acetylcholinesterase activity(GO:0003990) choline binding(GO:0033265)
0.1 0.3 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.1 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0 0.2 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.5 GO:0005545 1-phosphatidylinositol binding(GO:0005545)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 PID AURORA B PATHWAY Aurora B signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin