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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for PAX3

Z-value: 0.62

Motif logo

Transcription factors associated with PAX3

Gene Symbol Gene ID Gene Info
ENSG00000135903.20 PAX3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PAX3hg38_v1_chr2_-_222298808_2222988950.135.4e-01Click!

Activity profile of PAX3 motif

Sorted Z-values of PAX3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of PAX3

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr1_+_100719734 3.94 ENST00000370119.8
ENST00000294728.7
ENST00000347652.6
ENST00000370115.1
vascular cell adhesion molecule 1
chr2_+_151357583 2.92 ENST00000243347.5
TNF alpha induced protein 6
chr10_+_113709261 1.86 ENST00000672138.1
ENST00000452490.3
caspase 7
chr10_+_89327977 1.66 ENST00000681277.1
interferon induced protein with tetratricopeptide repeats 3
chr10_+_89327989 1.65 ENST00000679923.1
ENST00000680085.1
ENST00000371818.9
ENST00000680779.1
interferon induced protein with tetratricopeptide repeats 3
chr15_-_79971164 1.63 ENST00000335661.6
ENST00000267953.4
ENST00000677151.1
BCL2 related protein A1
chr18_+_26226417 1.36 ENST00000269142.10
TATA-box binding protein associated factor 4b
chr6_+_14117764 1.24 ENST00000379153.4
CD83 molecule
chr6_-_37258110 1.18 ENST00000357219.4
ENST00000652386.1
ENST00000652639.1
transmembrane protein 217
chr15_-_43330537 0.83 ENST00000305641.7
ENST00000567039.1
leucine carboxyl methyltransferase 2
chr18_+_26226472 0.82 ENST00000578121.5
TATA-box binding protein associated factor 4b
chr5_-_35938572 0.78 ENST00000651391.1
ENST00000397366.5
ENST00000513623.5
ENST00000514524.2
ENST00000397367.6
calcyphosine like
chr18_+_58362467 0.76 ENST00000675101.1
NEDD4 like E3 ubiquitin protein ligase
chr3_+_133573637 0.72 ENST00000264993.8
CDV3 homolog
chr12_+_112125531 0.70 ENST00000549358.5
ENST00000257604.9
ENST00000548092.5
ENST00000412615.7
ENST00000552896.1
TRAF-type zinc finger domain containing 1
chr22_+_30425743 0.70 ENST00000266263.10
ENST00000355143.8
ENST00000407550.3
mitochondrial fission process 1
chr18_+_61333424 0.67 ENST00000262717.9
cadherin 20
chr4_+_8580387 0.61 ENST00000382487.5
G protein-coupled receptor 78
chr17_-_69150062 0.59 ENST00000522787.5
ENST00000521538.5
ATP binding cassette subfamily A member 10
chr11_+_71999927 0.58 ENST00000393707.4
interleukin 18 binding protein
chrX_+_30247139 0.55 ENST00000397548.4
MAGE family member B1
chr19_+_55339867 0.55 ENST00000255613.8
lysine methyltransferase 5C
chr1_-_153958576 0.53 ENST00000368630.7
ENST00000368633.2
CREB regulated transcription coactivator 2
chr4_-_140568958 0.51 ENST00000262999.4
uncoupling protein 1
chr19_+_52190006 0.50 ENST00000454220.6
ENST00000322088.11
ENST00000477989.1
ENST00000628959.1
protein phosphatase 2 scaffold subunit Aalpha
chr19_+_37594830 0.50 ENST00000589117.5
zinc finger protein 540
chr2_-_113756604 0.49 ENST00000409342.1
solute carrier family 35 member F5
chr4_+_155758990 0.49 ENST00000505154.5
ENST00000652626.1
ENST00000502959.5
ENST00000264424.13
ENST00000505764.5
ENST00000507146.5
ENST00000503520.5
guanylate cyclase 1 soluble subunit beta 1
chr10_+_116545907 0.48 ENST00000369221.2
pancreatic lipase
chr15_-_82952683 0.47 ENST00000450735.7
ENST00000304231.12
homer scaffold protein 2
chr22_-_43862480 0.44 ENST00000330884.9
sulfotransferase family 4A member 1
chr3_+_14675128 0.43 ENST00000435614.5
ENST00000253697.8
ENST00000412910.1
chromosome 3 open reading frame 20
chr9_-_70414657 0.42 ENST00000377126.4
Kruppel like factor 9
chr19_+_54497879 0.42 ENST00000412608.5
ENST00000610651.1
leukocyte associated immunoglobulin like receptor 2
chrX_+_38561530 0.41 ENST00000378482.7
ENST00000286824.6
tetraspanin 7
chr19_-_2783308 0.41 ENST00000677562.1
ENST00000677754.1
small glutamine rich tetratricopeptide repeat containing alpha
chr19_-_47545261 0.39 ENST00000595558.1
ENST00000263351.9
zinc finger protein 541
chr4_-_170003738 0.38 ENST00000502832.1
ENST00000393704.3
microfibril associated protein 3 like
chr1_+_171314171 0.36 ENST00000367749.4
flavin containing dimethylaniline monoxygenase 4
chrX_+_37990773 0.36 ENST00000341016.5
H2A.P histone
chr10_+_102245371 0.35 ENST00000676513.1
ENST00000676939.1
ENST00000677947.1
ENST00000677247.1
ENST00000369983.4
ENST00000678351.1
ENST00000679238.1
ENST00000677439.1
ENST00000677240.1
ENST00000677618.1
ENST00000673650.1
ENST00000674034.1
ENST00000676993.1
golgi brefeldin A resistant guanine nucleotide exchange factor 1
chr5_+_50665899 0.35 ENST00000505697.6
poly(ADP-ribose) polymerase family member 8
chr2_+_42169332 0.35 ENST00000402711.6
ENST00000318522.10
EMAP like 4
chr19_+_11541125 0.34 ENST00000587087.5
calponin 1
chr19_-_2783241 0.34 ENST00000676943.1
ENST00000589251.5
ENST00000221566.7
ENST00000676984.1
small glutamine rich tetratricopeptide repeat containing alpha
chr9_-_21368962 0.34 ENST00000610660.1
interferon alpha 13
chr21_-_36079382 0.34 ENST00000399201.5
SET domain containing 4
chr11_-_615921 0.33 ENST00000348655.11
ENST00000525445.6
ENST00000330243.9
interferon regulatory factor 7
chrX_+_154542194 0.32 ENST00000618670.4
inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
chr14_-_64338096 0.32 ENST00000554572.5
ENST00000358599.9
estrogen receptor 2
chr9_-_111759508 0.31 ENST00000394777.8
ENST00000394779.7
shortage in chiasmata 1
chr1_-_205211669 0.31 ENST00000367162.8
dual serine/threonine and tyrosine protein kinase
chr5_+_141370236 0.30 ENST00000576222.2
ENST00000618934.1
protocadherin gamma subfamily B, 3
chr8_+_103414703 0.30 ENST00000616836.4
ENST00000297579.9
DDB1 and CUL4 associated factor 13
chr7_-_103989516 0.29 ENST00000343529.9
ENST00000424685.3
reelin
chr21_-_37267511 0.29 ENST00000398998.1
VPS26 endosomal protein sorting factor C
chr2_+_42169434 0.28 ENST00000401738.3
EMAP like 4
chr8_+_144104512 0.28 ENST00000534585.5
MAF1 homolog, negative regulator of RNA polymerase III
chr8_+_144104454 0.28 ENST00000322428.10
MAF1 homolog, negative regulator of RNA polymerase III
chr8_-_30912998 0.28 ENST00000643185.2
testis expressed 15, meiosis and synapsis associated
chr1_-_205211535 0.27 ENST00000367161.7
dual serine/threonine and tyrosine protein kinase
chr11_-_120138104 0.27 ENST00000341846.10
tripartite motif containing 29
chr7_+_142399860 0.25 ENST00000390364.3
T cell receptor beta variable 10-1
chr4_-_167234579 0.25 ENST00000502330.5
ENST00000357154.7
ENST00000421836.6
SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3
chr7_+_142598016 0.25 ENST00000620773.1
T cell receptor beta variable 16
chr14_-_59465327 0.25 ENST00000395116.1
G protein-coupled receptor 135
chr11_+_313391 0.24 ENST00000680802.1
ENST00000528780.5
ENST00000681761.1
ENST00000681821.1
ENST00000328221.5
interferon induced transmembrane protein 1
chr9_-_97922487 0.24 ENST00000455506.1
ENST00000375117.8
ENST00000375119.8
ENST00000611338.4
tRNA methyltransferase O
chr3_-_119660580 0.24 ENST00000493094.6
ENST00000264231.7
ENST00000468801.1
popeye domain containing 2
chr6_+_31971831 0.24 ENST00000375331.7
ENST00000375333.3
serine/threonine kinase 19
chr1_+_203475798 0.24 ENST00000343110.3
proline and arginine rich end leucine rich repeat protein
chr12_+_10307950 0.23 ENST00000543420.5
ENST00000543777.5
killer cell lectin like receptor D1
chr6_+_163414637 0.23 ENST00000453779.6
ENST00000275262.11
ENST00000392127.6
QKI, KH domain containing RNA binding
chr8_-_10655137 0.23 ENST00000382483.4
RP1 like 1
chr11_+_31369834 0.22 ENST00000465995.6
DnaJ heat shock protein family (Hsp40) member C24
chrX_+_47218232 0.22 ENST00000457458.6
ENST00000522883.1
cyclin dependent kinase 16
chr11_+_65354745 0.22 ENST00000309880.6
tigger transposable element derived 3
chr4_-_167234266 0.22 ENST00000511269.5
ENST00000506697.5
ENST00000512042.1
SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3
chr10_+_94402486 0.22 ENST00000225235.5
TBC1 domain family member 12
chr4_-_167234552 0.22 ENST00000512648.5
SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3
chr7_-_142962206 0.22 ENST00000460479.2
ENST00000476829.5
ENST00000355265.7
Kell metallo-endopeptidase (Kell blood group)
chr7_+_29479712 0.22 ENST00000412711.6
chimerin 2
chr4_-_167234426 0.21 ENST00000541354.5
ENST00000509854.5
ENST00000512681.5
ENST00000357545.9
ENST00000510741.5
ENST00000510403.5
SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3
chr20_-_23826721 0.21 ENST00000304725.3
cystatin SA
chr17_-_62806632 0.21 ENST00000583803.1
ENST00000456609.6
membrane associated ring-CH-type finger 10
chr22_+_20117734 0.21 ENST00000416427.5
ENST00000421656.5
ENST00000423859.5
ENST00000418705.2
RAN binding protein 1
chr11_+_73647549 0.20 ENST00000227214.10
ENST00000398494.8
ENST00000543085.5
pleckstrin homology domain containing B1
chr17_+_4951758 0.20 ENST00000518175.1
enolase 3
chr14_+_20469399 0.20 ENST00000361505.10
ENST00000553591.1
purine nucleoside phosphorylase
chr19_+_51225059 0.20 ENST00000436584.6
ENST00000421133.6
ENST00000262262.5
ENST00000391796.7
CD33 molecule
chr6_+_29111560 0.20 ENST00000377169.2
olfactory receptor family 2 subfamily J member 3
chr1_-_13198130 0.19 ENST00000638454.1
PRAME family member 13
chr22_+_38705922 0.19 ENST00000216044.10
GTP binding protein 1
chr6_-_5260883 0.19 ENST00000330636.9
LYR motif containing 4
chr3_+_128051610 0.19 ENST00000464451.5
SEC61 translocon subunit alpha 1
chr17_-_41382298 0.19 ENST00000394001.3
keratin 34
chr10_-_124450027 0.17 ENST00000451024.5
NK1 homeobox 2
chr8_+_116938180 0.17 ENST00000378279.4
alanine and arginine rich domain containing protein
chr2_+_218659656 0.17 ENST00000443791.5
ENST00000359273.8
ENST00000392111.7
ENST00000392109.5
ENST00000392110.6
ENST00000423377.5
ENST00000412366.5
BCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone
chr19_-_35228699 0.17 ENST00000324675.3
family with sequence similarity 187 member B
chr9_+_128787243 0.17 ENST00000372648.10
TBC1 domain family member 13
chr2_-_218659468 0.17 ENST00000450560.1
ENST00000449707.5
ENST00000440934.2
zinc finger protein 142
chr19_-_45076465 0.16 ENST00000303809.7
zinc finger protein 296
chr9_+_33795551 0.16 ENST00000379405.4
serine protease 3
chr1_+_145719483 0.16 ENST00000369288.7
CD160 molecule
chr1_-_183418364 0.16 ENST00000287713.7
nicotinamide nucleotide adenylyltransferase 2
chr5_+_141100466 0.16 ENST00000231130.3
protocadherin beta 3
chr2_+_167868948 0.16 ENST00000392690.3
beta-1,3-galactosyltransferase 1
chr2_-_157327699 0.15 ENST00000397283.6
ermin
chrX_+_71144818 0.15 ENST00000536169.5
ENST00000358741.4
ENST00000395855.6
ENST00000374051.7
neuroligin 3
chr2_-_218659592 0.15 ENST00000411696.7
zinc finger protein 142
chr7_+_100219236 0.14 ENST00000317271.2
PVR related immunoglobulin domain containing
chr11_+_9461003 0.14 ENST00000438144.6
ENST00000396602.7
ENST00000526657.5
ENST00000299606.6
ENST00000534265.5
ENST00000412390.6
zinc finger protein 143
chr6_+_163414701 0.14 ENST00000361752.8
QKI, KH domain containing RNA binding
chr12_+_10307818 0.14 ENST00000350274.9
ENST00000336164.9
killer cell lectin like receptor D1
chr7_+_142384328 0.14 ENST00000390361.3
T cell receptor beta variable 7-3
chr19_+_37594867 0.14 ENST00000316433.9
ENST00000590588.5
ENST00000586134.5
ENST00000586792.5
zinc finger protein 540
chr1_-_26890237 0.13 ENST00000431781.2
ENST00000374135.9
GPN-loop GTPase 2
chr15_+_45430579 0.13 ENST00000558435.5
ENST00000344300.3
ENST00000396650.7
chromosome 15 open reading frame 48
chr2_+_183117509 0.13 ENST00000442895.6
ENST00000446612.5
ENST00000409798.5
nucleoporin 35
chr14_+_73612517 0.13 ENST00000645972.2
acyl-CoA thioesterase 6
chr2_-_24972032 0.13 ENST00000534855.5
DnaJ heat shock protein family (Hsp40) member C27
chr11_+_123902167 0.13 ENST00000641687.1
olfactory receptor family 8 subfamily D member 4
chrX_-_49073989 0.12 ENST00000376386.3
ENST00000553851.3
PRA1 domain family member 2
chr1_+_50048014 0.12 ENST00000448907.7
ELAV like RNA binding protein 4
chr15_+_51681483 0.12 ENST00000542355.6
ENST00000220478.8
ENST00000558709.1
secretogranin III
chr19_-_7021431 0.12 ENST00000636986.2
ENST00000637800.1
methyl-CpG binding domain protein 3 like 2B
chr19_+_15010720 0.12 ENST00000292574.4
coiled-coil domain containing 105
chr6_+_29173303 0.11 ENST00000377167.3
olfactory receptor family 2 subfamily J member 2
chr2_-_24971900 0.11 ENST00000264711.7
DnaJ heat shock protein family (Hsp40) member C27
chr18_-_57803307 0.10 ENST00000648908.2
ATPase phospholipid transporting 8B1
chr1_+_6034980 0.10 ENST00000378092.6
ENST00000472700.7
potassium voltage-gated channel subfamily A regulatory beta subunit 2
chr1_-_205121986 0.10 ENST00000367164.1
RB binding protein 5, histone lysine methyltransferase complex subunit
chr11_+_67606894 0.10 ENST00000532303.5
ENST00000532244.5
ENST00000528328.1
ENST00000322776.11
ENST00000529927.5
ENST00000532343.5
ENST00000415352.6
ENST00000533075.5
ENST00000529867.5
ENST00000530638.1
NADH:ubiquinone oxidoreductase core subunit V1
chr17_-_75154503 0.10 ENST00000409753.8
ENST00000581874.1
Jupiter microtubule associated homolog 1
chr19_-_34677157 0.10 ENST00000601241.6
secretoglobin family 2B member 2
chr16_+_27203480 0.10 ENST00000286096.9
lysine demethylase 8
chr2_+_120013111 0.10 ENST00000331393.8
ENST00000443124.5
erythrocyte membrane protein band 4.1 like 5
chr9_+_128787331 0.10 ENST00000223865.8
TBC1 domain family member 13
chr13_-_60013178 0.09 ENST00000498416.2
ENST00000465066.5
diaphanous related formin 3
chr1_+_40040219 0.09 ENST00000372797.7
ENST00000372802.5
ENST00000449311.5
cyclase associated actin cytoskeleton regulatory protein 1
chr11_-_14643617 0.09 ENST00000418988.2
proteasome 20S subunit alpha 1
chr15_-_78077657 0.09 ENST00000300584.8
ENST00000409931.7
TBC1 domain family member 2B
chr7_+_142492121 0.09 ENST00000390374.3
T cell receptor beta variable 7-6
chr9_+_101398841 0.09 ENST00000339664.7
ENST00000374861.7
ENST00000259395.4
ENST00000615466.1
zinc finger protein 189
chr1_-_205121964 0.08 ENST00000264515.11
RB binding protein 5, histone lysine methyltransferase complex subunit
chr1_+_35930712 0.08 ENST00000324350.9
argonaute RISC catalytic component 3
chr21_-_37267300 0.08 ENST00000309117.11
ENST00000476950.5
ENST00000399001.5
VPS26 endosomal protein sorting factor C
chr16_-_18375069 0.07 ENST00000545114.5
nuclear pore complex interacting protein family, member A9
chr11_-_31369728 0.07 ENST00000684477.1
ENST00000452803.1
doublecortin domain containing 1
chr5_-_180071708 0.07 ENST00000522208.6
ENST00000521389.6
ring finger protein 130
chr8_-_70071226 0.07 ENST00000276594.3
PR/SET domain 14
chr16_-_71489276 0.06 ENST00000564230.5
ENST00000565637.5
ENST00000288177.10
zinc finger protein 19
chr1_+_145719468 0.06 ENST00000616463.1
CD160 molecule
chr13_+_31739520 0.06 ENST00000298386.7
relaxin family peptide receptor 2
chr12_+_10010627 0.06 ENST00000338896.11
ENST00000396502.5
C-type lectin domain family 12 member B
chr7_-_30026617 0.06 ENST00000222803.10
FKBP prolyl isomerase 14
chr2_-_68252482 0.06 ENST00000234310.8
protein phosphatase 3 regulatory subunit B, alpha
chr16_+_16350098 0.06 ENST00000331436.6
novel member of the nuclear pore complex interacting protein NPIP gene family
chr17_+_7932101 0.05 ENST00000576538.5
ENST00000380262.7
ENST00000563694.6
ENST00000570782.1
centrobin, centriole duplication and spindle assembly protein
chr1_-_153150884 0.05 ENST00000368748.5
small proline rich protein 2G
chr21_-_28992947 0.05 ENST00000389194.7
ENST00000389195.7
ENST00000614971.4
listerin E3 ubiquitin protein ligase 1
chr19_-_41959266 0.05 ENST00000600292.5
ENST00000601078.5
ENST00000601891.5
ENST00000222008.11
Rab acceptor 1
chr11_+_61392576 0.05 ENST00000515837.7
transmembrane protein 216
chr6_+_108295037 0.05 ENST00000368977.9
ENST00000421954.5
AFG1 like ATPase
chr16_-_18358582 0.05 ENST00000327792.6
nuclear pore complex interacting protein family, member A9
chr19_-_36916268 0.05 ENST00000391711.8
zinc finger protein 829
chr12_-_10409757 0.04 ENST00000309384.2
killer cell lectin like receptor C4
chr21_-_28992815 0.04 ENST00000361371.10
listerin E3 ubiquitin protein ligase 1
chr19_-_50333504 0.04 ENST00000474951.1
potassium voltage-gated channel subfamily C member 3
chr6_+_133241566 0.04 ENST00000531901.5
EYA transcriptional coactivator and phosphatase 4
chr1_-_203351115 0.04 ENST00000354955.5
fibromodulin
chr3_+_49199477 0.03 ENST00000452691.7
ENST00000366429.2
interactor of HORMAD1 1
chr2_-_217842154 0.03 ENST00000446688.5
tensin 1
chr1_+_99264275 0.03 ENST00000457765.6
phospholipid phosphatase related 4
chr14_-_24114913 0.03 ENST00000561028.6
ENST00000558280.1
neural retina leucine zipper
chr14_+_21749163 0.03 ENST00000390427.3
T cell receptor alpha variable 5
chr10_-_100529854 0.03 ENST00000370320.4
ENST00000299166.9
ENST00000370322.5
NADH:ubiquinone oxidoreductase subunit B8
chr2_-_216860042 0.03 ENST00000236979.2
transition protein 1
chr19_+_9247344 0.02 ENST00000641946.1
olfactory receptor family 7 subfamily E member 24
chr15_-_42491105 0.02 ENST00000565380.5
ENST00000564754.7
zinc finger protein 106
chr1_+_247507058 0.02 ENST00000527084.5
ENST00000536561.5
ENST00000527541.5
ENST00000366491.6
ENST00000366489.5
ENST00000526896.5
germinal center associated signaling and motility like
chr11_-_33717409 0.02 ENST00000651485.1
CD59 molecule (CD59 blood group)
chr16_-_74985070 0.01 ENST00000616369.4
ENST00000262144.11
WD repeat domain 59
chr15_+_43330646 0.01 ENST00000562188.7
ENST00000428046.7
ENST00000389651.8
adenosine deaminase like
chr3_-_54967088 0.01 ENST00000493075.1
leucine rich repeats and transmembrane domains 1
chr6_-_31972123 0.01 ENST00000337523.10
decapping exoribonuclease
chr19_-_55063170 0.01 ENST00000610356.4
retinol dehydrogenase 13
chr7_+_142749465 0.01 ENST00000486171.5
ENST00000619214.4
ENST00000311737.12
serine protease 1
chr17_+_39200334 0.00 ENST00000579260.5
ENST00000582193.5
ribosomal protein L19
chr7_+_128758947 0.00 ENST00000493278.1
calumenin
chr1_+_206897435 0.00 ENST00000391929.7
ENST00000294984.7
ENST00000611909.4
ENST00000367093.3
interleukin 24
chr2_+_170178136 0.00 ENST00000409044.7
ENST00000408978.9
myosin IIIB
chr4_+_15374541 0.00 ENST00000382383.7
ENST00000429690.5
C1q and TNF related 7

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.9 GO:0022614 membrane to membrane docking(GO:0022614)
0.2 1.9 GO:0072733 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.2 3.3 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.2 0.7 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.2 0.5 GO:1903537 meiotic spindle elongation(GO:0051232) meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
0.1 1.2 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.1 0.6 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.1 0.3 GO:0097477 lateral motor column neuron migration(GO:0097477)
0.1 0.3 GO:0048200 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.1 2.9 GO:0030728 ovulation(GO:0030728)
0.1 0.5 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.1 0.8 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1 0.3 GO:0034124 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
0.1 0.4 GO:0051414 response to cortisol(GO:0051414)
0.0 0.2 GO:0045204 MAPK export from nucleus(GO:0045204)
0.0 0.1 GO:0044376 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.0 0.6 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 0.9 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.5 GO:0002024 diet induced thermogenesis(GO:0002024)
0.0 0.2 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.0 2.2 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 1.6 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.1 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.0 0.9 GO:1900116 extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0 0.5 GO:0048875 chemical homeostasis within a tissue(GO:0048875)
0.0 0.2 GO:0039019 pronephric nephron development(GO:0039019)
0.0 0.2 GO:0031133 regulation of axon diameter(GO:0031133)
0.0 0.2 GO:0046102 inosine metabolic process(GO:0046102)
0.0 0.5 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 0.8 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.7 GO:0014850 response to muscle activity(GO:0014850)
0.0 0.5 GO:0061365 positive regulation of triglyceride lipase activity(GO:0061365)
0.0 0.2 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.1 GO:0001827 inner cell mass cell fate commitment(GO:0001827) germ-line stem cell population maintenance(GO:0030718)
0.0 0.4 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.0 0.1 GO:0002769 natural killer cell inhibitory signaling pathway(GO:0002769)
0.0 0.4 GO:0042737 drug catabolic process(GO:0042737)
0.0 0.1 GO:0048319 apical constriction(GO:0003383) mesodermal cell migration(GO:0008078) axial mesoderm morphogenesis(GO:0048319)
0.0 0.3 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.2 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.3 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.3 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.0 0.2 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551)
0.0 0.1 GO:0021650 vestibulocochlear nerve formation(GO:0021650)
0.0 0.1 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.4 GO:0050427 purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0 0.7 GO:0045824 negative regulation of innate immune response(GO:0045824)
0.0 0.2 GO:0035455 response to interferon-alpha(GO:0035455)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.9 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.0 2.2 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.6 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.5 GO:0032426 stereocilium tip(GO:0032426)
0.0 2.2 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.3 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.1 GO:1990031 pinceau fiber(GO:1990031)
0.0 0.2 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.5 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.2 GO:0033269 internode region of axon(GO:0033269)
0.0 0.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.2 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.7 GO:0008131 primary amine oxidase activity(GO:0008131)
0.2 0.6 GO:0042007 interleukin-18 binding(GO:0042007)
0.2 0.6 GO:0000994 RNA polymerase III core binding(GO:0000994)
0.1 2.2 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.1 0.7 GO:1904288 BAT3 complex binding(GO:1904288)
0.1 0.4 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.1 1.6 GO:0051400 BH domain binding(GO:0051400)
0.1 0.4 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.1 2.9 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 1.9 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1 0.3 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.1 0.5 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.1 0.5 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 0.3 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.1 0.4 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.2 GO:0002060 purine nucleobase binding(GO:0002060)
0.0 0.2 GO:0016426 tRNA (adenine) methyltransferase activity(GO:0016426)
0.0 0.2 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309)
0.0 0.9 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.8 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.5 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.8 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.0 0.3 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.4 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.2 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.6 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.5 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.2 GO:0032393 MHC class I receptor activity(GO:0032393)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.9 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.9 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 1.2 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 2.2 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.3 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 4.7 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.3 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 2.2 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.5 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.3 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.3 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.6 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.3 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.4 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 1.5 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.5 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.2 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism