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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for PAX8

Z-value: 0.66

Motif logo

Transcription factors associated with PAX8

Gene Symbol Gene ID Gene Info
ENSG00000125618.18 PAX8

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PAX8hg38_v1_chr2_-_113241779_113241810-0.272.0e-01Click!

Activity profile of PAX8 motif

Sorted Z-values of PAX8 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of PAX8

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr1_-_169734064 4.24 ENST00000333360.12
selectin E
chr6_-_44265541 1.74 ENST00000619360.6
NFKB inhibitor epsilon
chr14_-_91244669 1.70 ENST00000650645.1
G protein-coupled receptor 68
chr15_+_67128103 1.49 ENST00000558894.5
SMAD family member 3
chr12_+_26195647 1.49 ENST00000535504.1
sarcospan
chr12_+_77830886 1.43 ENST00000397909.7
ENST00000549464.5
neuron navigator 3
chr14_-_91244508 1.43 ENST00000535815.5
ENST00000529102.1
G protein-coupled receptor 68
chr11_+_20022550 1.12 ENST00000533917.5
neuron navigator 2
chr6_-_81752671 1.04 ENST00000320172.11
ENST00000369754.7
ENST00000369756.3
terminal nucleotidyltransferase 5A
chr1_-_173207322 1.04 ENST00000281834.4
TNF superfamily member 4
chr1_+_159439722 1.03 ENST00000641630.1
ENST00000423932.6
olfactory receptor family 10 subfamily J member 1
chr19_-_55160668 0.92 ENST00000588076.1
dynein axonemal assembly factor 3
chr12_-_55842950 0.91 ENST00000548629.5
matrix metallopeptidase 19
chr10_+_89332484 0.82 ENST00000371811.4
ENST00000680037.1
ENST00000679583.1
ENST00000679897.1
interferon induced protein with tetratricopeptide repeats 3
chr10_+_113709261 0.73 ENST00000672138.1
ENST00000452490.3
caspase 7
chr17_+_58169401 0.69 ENST00000641866.1
olfactory receptor family 4 subfamily D member 2
chr4_+_8580387 0.68 ENST00000382487.5
G protein-coupled receptor 78
chr12_-_128823942 0.68 ENST00000266771.10
solute carrier family 15 member 4
chr2_-_223945322 0.67 ENST00000233055.9
WD repeat and FYVE domain containing 1
chr6_-_134318097 0.67 ENST00000367858.10
ENST00000533224.1
serum/glucocorticoid regulated kinase 1
chr2_-_174847525 0.65 ENST00000295497.12
ENST00000652036.1
ENST00000444394.6
ENST00000650731.1
chimerin 1
chr22_+_20774092 0.63 ENST00000215727.10
serpin family D member 1
chr2_-_174847765 0.62 ENST00000443238.6
chimerin 1
chr12_+_75480800 0.62 ENST00000456650.7
GLI pathogenesis related 1
chr6_-_138107412 0.62 ENST00000421351.4
p53 apoptosis effector related to PMP22
chr10_+_84173793 0.61 ENST00000372126.4
chromosome 10 open reading frame 99
chr1_+_86547070 0.55 ENST00000370563.3
chloride channel accessory 4
chrX_+_140091415 0.54 ENST00000453380.2
novel protein (LOC389895)
chr12_+_75480745 0.52 ENST00000266659.8
GLI pathogenesis related 1
chr2_-_24328113 0.48 ENST00000622089.4
intersectin 2
chr17_-_62806632 0.47 ENST00000583803.1
ENST00000456609.6
membrane associated ring-CH-type finger 10
chr17_+_7558712 0.47 ENST00000338784.9
ENST00000625791.2
TNF superfamily member 13
chr2_+_161136901 0.46 ENST00000259075.6
ENST00000432002.5
TRAF family member associated NFKB activator
chr7_-_97872394 0.45 ENST00000455086.5
ENST00000394308.8
ENST00000453600.5
asparagine synthetase (glutamine-hydrolyzing)
chr3_-_190122317 0.45 ENST00000427335.6
prolyl 3-hydroxylase 2
chr18_+_45825666 0.43 ENST00000389474.8
sialic acid binding Ig like lectin 15
chr8_+_119067239 0.43 ENST00000332843.3
collectin subfamily member 10
chr7_-_80919017 0.42 ENST00000265361.8
semaphorin 3C
chr17_+_7558774 0.42 ENST00000396545.4
TNF superfamily member 13
chr3_+_98168700 0.42 ENST00000383696.4
olfactory receptor family 5 subfamily H member 15
chr17_+_7558296 0.41 ENST00000438470.5
ENST00000436057.5
TNF superfamily member 13
chr7_+_20615653 0.41 ENST00000404938.7
ATP binding cassette subfamily B member 5
chr10_+_102152380 0.40 ENST00000605788.6
ENST00000488254.6
ENST00000461421.5
ENST00000476468.5
ENST00000370007.5
nucleolar and coiled-body phosphoprotein 1
chr10_+_69088096 0.40 ENST00000242465.4
serglycin
chr17_+_58166982 0.39 ENST00000545221.2
olfactory receptor family 4 subfamily D member 2
chr12_+_71664352 0.38 ENST00000547843.1
THAP domain containing 2
chr13_+_76952467 0.38 ENST00000449753.2
aconitate decarboxylase 1
chr9_-_132079856 0.37 ENST00000651555.1
ENST00000651950.1
ENST00000357028.6
ENST00000474263.1
ENST00000292035.10
mediator complex subunit 27
chr15_-_88467353 0.37 ENST00000312475.5
ENST00000558531.1
mitochondrial ribosomal protein L46
chr10_+_102152169 0.37 ENST00000405356.5
nucleolar and coiled-body phosphoprotein 1
chr7_-_76626127 0.37 ENST00000454397.1
POM121 and ZP3 fusion
chr20_+_4171709 0.36 ENST00000379460.6
spermine oxidase
chr9_-_115091018 0.36 ENST00000542877.5
ENST00000537320.5
ENST00000341037.8
tenascin C
chr17_+_7558465 0.36 ENST00000349228.8
TNF superfamily member 13
chr12_-_49900250 0.35 ENST00000552669.5
Fas apoptotic inhibitory molecule 2
chr7_-_138002017 0.34 ENST00000452463.5
ENST00000456390.5
ENST00000330387.11
cAMP responsive element binding protein 3 like 2
chr22_-_32255344 0.33 ENST00000266086.6
solute carrier family 5 member 4
chr17_+_7558258 0.33 ENST00000483039.5
ENST00000380535.8
ENST00000396542.5
TNF superfamily member 13
chr6_+_160121859 0.32 ENST00000324965.8
ENST00000457470.6
solute carrier family 22 member 1
chr21_-_7789509 0.32 ENST00000646133.1
small integral membrane protein 34B
chr3_-_71493500 0.31 ENST00000648380.1
ENST00000650295.1
forkhead box P1
chr2_+_218659749 0.30 ENST00000439945.5
ENST00000431802.5
BCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone
chr2_-_26641363 0.29 ENST00000288861.5
calcium and integrin binding family member 4
chr14_+_72926377 0.29 ENST00000353777.7
ENST00000358377.7
ENST00000394234.6
ENST00000509153.5
ENST00000555042.5
DDB1 and CUL4 associated factor 4
chr4_-_46909206 0.29 ENST00000396533.5
cytochrome c oxidase subunit 7B2
chr12_-_10420550 0.29 ENST00000381903.2
ENST00000396439.7
killer cell lectin like receptor C3
chr22_-_50085414 0.29 ENST00000311597.10
modulator of VRAC current 1
chr19_+_35140022 0.29 ENST00000588081.5
ENST00000589121.1
FXYD domain containing ion transport regulator 1
chr22_-_50085331 0.28 ENST00000395876.6
modulator of VRAC current 1
chr6_+_31158518 0.28 ENST00000376255.4
ENST00000376257.8
transcription factor 19
chr1_-_160282458 0.27 ENST00000485079.1
novel protein
chr5_+_70025247 0.27 ENST00000380751.9
ENST00000380750.8
ENST00000503931.5
ENST00000506542.1
small EDRK-rich factor 1B
chr6_+_160121809 0.26 ENST00000366963.9
solute carrier family 22 member 1
chr20_-_43726989 0.26 ENST00000373003.2
gametocyte specific factor 1 like
chr2_-_79086847 0.26 ENST00000454188.5
regenerating family member 1 beta
chr17_-_44066595 0.26 ENST00000585388.2
ENST00000293406.8
LSM12 homolog
chr6_-_32816910 0.26 ENST00000447394.1
ENST00000438763.7
major histocompatibility complex, class II, DO beta
chr12_-_10098940 0.25 ENST00000420265.2
C-type lectin domain family 1 member A
chr19_+_49665926 0.25 ENST00000246784.8
BCL2 like 12
chr17_-_82059973 0.25 ENST00000577574.5
dihydrouridine synthase 1 like
chr22_-_37007844 0.25 ENST00000381821.2
testis expressed 33
chr7_-_138001794 0.24 ENST00000616381.4
ENST00000620715.4
cAMP responsive element binding protein 3 like 2
chr7_+_130344810 0.24 ENST00000497503.5
ENST00000463587.5
ENST00000461828.5
ENST00000474905.6
ENST00000494311.1
ENST00000466363.6
carboxypeptidase A5
chr8_-_7056729 0.24 ENST00000330590.4
defensin alpha 5
chr22_-_37007798 0.24 ENST00000402860.7
testis expressed 33
chr22_-_37007818 0.24 ENST00000405091.6
testis expressed 33
chr3_+_319683 0.24 ENST00000620033.4
cell adhesion molecule L1 like
chr1_-_27626229 0.24 ENST00000399173.5
FGR proto-oncogene, Src family tyrosine kinase
chr12_-_10098977 0.24 ENST00000315330.8
ENST00000457018.6
C-type lectin domain family 1 member A
chr1_+_171314171 0.24 ENST00000367749.4
flavin containing dimethylaniline monoxygenase 4
chr5_+_70900669 0.23 ENST00000511162.1
ENST00000317633.14
ENST00000354833.7
ENST00000513436.6
ENST00000504458.1
small EDRK-rich factor 1A
chr2_+_218659656 0.23 ENST00000443791.5
ENST00000359273.8
ENST00000392111.7
ENST00000392109.5
ENST00000392110.6
ENST00000423377.5
ENST00000412366.5
BCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone
chr15_+_89088417 0.23 ENST00000569550.5
ENST00000565066.5
ENST00000565973.5
ENST00000352732.10
abhydrolase domain containing 2, acylglycerol lipase
chr7_+_128672275 0.23 ENST00000684498.1
ENST00000641605.1
ENST00000682356.1
ENST00000477515.3
family with sequence similarity 71 member F2
chr3_-_161372821 0.23 ENST00000617024.1
ENST00000359175.8
serine palmitoyltransferase small subunit B
chrX_-_23907887 0.23 ENST00000379226.9
apolipoprotein O
chr11_+_27055215 0.22 ENST00000525090.1
gamma-butyrobetaine hydroxylase 1
chr19_+_35448251 0.22 ENST00000599180.3
free fatty acid receptor 2
chr20_+_2814981 0.21 ENST00000603872.2
ENST00000380589.4
chromosome 20 open reading frame 141
chr9_-_127930777 0.21 ENST00000388747.9
phosphatidylinositol-4-phosphate 5-kinase like 1
chr12_-_55842927 0.21 ENST00000322569.9
ENST00000409200.7
matrix metallopeptidase 19
chr2_-_218659592 0.20 ENST00000411696.7
zinc finger protein 142
chr9_-_27529705 0.20 ENST00000262244.6
MOB kinase activator 3B
chr1_+_180196536 0.20 ENST00000443059.1
quiescin sulfhydryl oxidase 1
chr19_-_49665807 0.20 ENST00000593337.5
ENST00000598808.5
ENST00000600453.1
ENST00000593818.5
ENST00000377139.8
ENST00000597198.5
ENST00000601809.5
ENST00000377135.8
interferon regulatory factor 3
chr7_+_107891135 0.19 ENST00000639772.1
ENST00000440410.5
ENST00000437604.6
ENST00000205402.10
dihydrolipoamide dehydrogenase
chrX_-_57680260 0.19 ENST00000434992.1
NLR family pyrin domain containing 2B
chr1_+_27773189 0.19 ENST00000373943.9
ENST00000440806.2
syntaxin 12
chr19_+_7920313 0.19 ENST00000221573.11
ENST00000595637.1
small nuclear RNA activating complex polypeptide 2
chr1_+_239386556 0.19 ENST00000676153.1
cholinergic receptor muscarinic 3
chr10_+_24449426 0.19 ENST00000307544.10
KIAA1217
chr12_+_57434778 0.19 ENST00000309668.3
inhibin subunit beta C
chr1_-_10976215 0.19 ENST00000520253.1
chromosome 1 open reading frame 127
chr4_+_36281591 0.19 ENST00000639862.2
ENST00000357504.7
death domain containing 1
chr10_-_43397220 0.19 ENST00000477108.5
ENST00000544000.5
heterogeneous nuclear ribonucleoprotein F
chr2_+_79025696 0.19 ENST00000272324.10
regenerating family member 3 gamma
chr2_+_79025678 0.18 ENST00000393897.6
regenerating family member 3 gamma
chr4_+_74365136 0.18 ENST00000244869.3
epiregulin
chr8_+_39934955 0.18 ENST00000502986.2
indoleamine 2,3-dioxygenase 2
chr8_-_20183127 0.18 ENST00000276373.10
ENST00000519026.5
ENST00000440926.3
ENST00000437980.3
solute carrier family 18 member A1
chr15_-_74082550 0.18 ENST00000290438.3
golgin A6 family member A
chr22_+_20116099 0.17 ENST00000430524.6
RAN binding protein 1
chr3_+_157436842 0.17 ENST00000295927.4
pentraxin 3
chr1_+_100352451 0.17 ENST00000361544.11
ENST00000370124.8
ENST00000336454.5
cell division cycle 14A
chr3_-_8769602 0.17 ENST00000316793.8
ENST00000431493.1
oxytocin receptor
chr17_-_75271205 0.17 ENST00000649805.1
MIF4G domain containing
chr13_-_102759059 0.17 ENST00000322527.4
coiled-coil domain containing 168
chr15_+_34345865 0.17 ENST00000333756.4
NUT midline carcinoma family member 1
chr16_-_3717505 0.17 ENST00000538171.5
ENST00000246957.10
TNF receptor associated protein 1
chr2_+_42169332 0.17 ENST00000402711.6
ENST00000318522.10
EMAP like 4
chr11_-_58575846 0.17 ENST00000395074.7
leupaxin
chr6_+_131250375 0.17 ENST00000474850.2
A-kinase anchoring protein 7
chr12_-_6851245 0.16 ENST00000540683.1
ENST00000229265.10
ENST00000535406.5
ENST00000422785.7
ENST00000538862.7
cell division cycle associated 3
chr4_+_118888918 0.16 ENST00000434046.6
synaptopodin 2
chr11_+_61229583 0.16 ENST00000544899.1
pepsinogen A4
chr12_-_57479848 0.16 ENST00000393791.8
ENST00000552249.1
Rho GTPase activating protein 9
chr19_-_3500664 0.16 ENST00000427575.6
deoxyhypusine hydroxylase
chr6_+_36885848 0.16 ENST00000355190.7
ENST00000373685.1
chromosome 6 open reading frame 89
chr3_-_16605416 0.16 ENST00000399444.7
deleted in azoospermia like
chr2_+_42169434 0.16 ENST00000401738.3
EMAP like 4
chr12_-_52680398 0.15 ENST00000252244.3
keratin 1
chr1_+_110451132 0.15 ENST00000271331.4
prokineticin 1
chr19_-_51034727 0.15 ENST00000525263.5
kallikrein related peptidase 12
chr15_-_43493076 0.15 ENST00000413546.1
tumor protein p53 binding protein 1
chr22_-_43862480 0.14 ENST00000330884.9
sulfotransferase family 4A member 1
chr1_-_152580511 0.14 ENST00000368787.4
late cornified envelope 3D
chrX_-_101052054 0.14 ENST00000372939.5
ENST00000372935.5
tRNA methyltransferase 2 homolog B
chr19_+_15737985 0.14 ENST00000641646.1
olfactory receptor family 10 subfamily H member 3
chr14_+_20781139 0.14 ENST00000304677.3
ribonuclease A family member k6
chr6_+_41228339 0.14 ENST00000448827.6
ENST00000341495.7
triggering receptor expressed on myeloid cells like 4
chr19_+_18683656 0.14 ENST00000338797.10
ENST00000321949.13
CREB regulated transcription coactivator 1
chr1_+_155033824 0.13 ENST00000295542.6
ENST00000423025.6
ENST00000368419.2
DC-STAMP domain containing 1
chr18_-_27990256 0.12 ENST00000675173.1
cadherin 2
chr7_+_7566866 0.12 ENST00000405785.5
ENST00000340080.9
ENST00000433635.1
meiosis regulator for oocyte development
chr19_-_3500625 0.12 ENST00000672935.1
deoxyhypusine hydroxylase
chr1_-_153541765 0.12 ENST00000368718.5
S100 calcium binding protein A5
chr17_+_7014774 0.12 ENST00000439424.6
chromosome 17 open reading frame 49
chr10_+_133527355 0.12 ENST00000252945.8
ENST00000421586.5
ENST00000418356.1
cytochrome P450 family 2 subfamily E member 1
chr20_-_3781440 0.11 ENST00000379756.3
sperm flagellar 1
chr14_+_64113054 0.11 ENST00000673869.1
spectrin repeat containing nuclear envelope protein 2
chr6_+_29306626 0.11 ENST00000377160.4
olfactory receptor family 14 subfamily J member 1
chr12_-_86256299 0.11 ENST00000552808.6
ENST00000547225.5
MGAT4 family member C
chr1_+_203765168 0.11 ENST00000367217.5
ENST00000442561.7
lymphocyte transmembrane adaptor 1
chr1_-_24415035 0.11 ENST00000374409.5
sperm tail PG-rich repeat containing 1
chr12_-_86256267 0.11 ENST00000620241.4
MGAT4 family member C
chr5_-_177516933 0.11 ENST00000629036.2
ENST00000625286.1
ENST00000330503.12
DEAD-box helicase 41
chr6_-_48111132 0.11 ENST00000398738.3
ENST00000679966.1
ENST00000339488.9
patched domain containing 4
chr1_+_171257930 0.11 ENST00000354841.4
flavin containing dimethylaniline monoxygenase 1
chr19_+_49665958 0.10 ENST00000594157.5
ENST00000600947.5
ENST00000598306.2
BCL2 like 12
chr4_+_70226116 0.10 ENST00000317987.6
follicular dendritic cell secreted protein
chr6_+_30163188 0.10 ENST00000619857.4
tripartite motif containing 15
chr19_-_58554960 0.10 ENST00000596708.1
ENST00000601220.5
ENST00000597848.1
charged multivesicular body protein 2A
chr1_-_37692205 0.10 ENST00000477060.1
ENST00000491981.5
ENST00000488137.5
ENST00000619962.1
chromosome 1 open reading frame 109
chr2_-_178807415 0.10 ENST00000342992.10
ENST00000460472.6
ENST00000589042.5
ENST00000591111.5
ENST00000360870.10
titin
chr19_-_55280194 0.10 ENST00000588971.1
ENST00000255631.9
ENST00000587551.1
HSPA (Hsp70) binding protein 1
chr1_+_248030070 0.10 ENST00000642011.1
ENST00000641771.1
olfactory receptor family 2 subfamily L member 2
chr14_-_106154113 0.10 ENST00000390603.2
immunoglobulin heavy variable 3-15
chr18_+_63542365 0.10 ENST00000269491.6
ENST00000382768.2
serpin family B member 12
chr1_+_40450053 0.09 ENST00000484445.5
ENST00000411995.6
ZFP69 zinc finger protein B
chr3_-_48609625 0.09 ENST00000203407.6
ubiquinol-cytochrome c reductase core protein 1
chr1_-_186680411 0.09 ENST00000367468.10
prostaglandin-endoperoxide synthase 2
chr7_+_95485934 0.09 ENST00000325885.6
ankyrin repeat and SOCS box containing 4
chr3_+_190388120 0.09 ENST00000456423.2
ENST00000264734.3
claudin 16
chr1_-_184037695 0.09 ENST00000361927.9
ENST00000649786.1
collagen beta(1-O)galactosyltransferase 2
chrX_+_55623400 0.09 ENST00000339140.5
forkhead box R2
chr13_+_27270814 0.09 ENST00000241463.5
RAS like family 11 member A
chr17_-_75785486 0.08 ENST00000586607.5
H3.3 histone B
chr11_+_113314569 0.08 ENST00000429951.5
ENST00000442859.5
ENST00000531164.5
ENST00000529850.5
ENST00000529221.6
ENST00000525965.5
tetratricopeptide repeat domain 12
chr21_-_34511243 0.08 ENST00000399284.1
potassium voltage-gated channel subfamily E regulatory subunit 1
chr19_-_55280063 0.08 ENST00000593263.5
ENST00000433386.7
HSPA (Hsp70) binding protein 1
chr12_-_95996302 0.08 ENST00000261208.8
ENST00000538703.5
ENST00000541929.5
histidine ammonia-lyase
chr16_-_89418292 0.08 ENST00000683497.1
ENST00000642443.1
ENST00000644784.1
ENST00000647238.1
novel protein
ankyrin repeat domain 11
chr1_+_89524819 0.08 ENST00000439853.6
ENST00000330947.7
ENST00000449440.5
ENST00000640258.1
leucine rich repeat containing 8 VRAC subunit B
chr5_+_55851349 0.08 ENST00000652347.2
interleukin 31 receptor A
chr19_+_16185380 0.08 ENST00000589852.5
ENST00000263384.12
ENST00000588367.5
ENST00000587351.1
family with sequence similarity 32 member A
chr2_+_90209873 0.08 ENST00000468879.1
immunoglobulin kappa variable 1D-43
chr4_+_71339014 0.08 ENST00000340595.4
solute carrier family 4 member 4
chr17_-_63931354 0.08 ENST00000647774.1
novel protein
chr12_-_71663791 0.08 ENST00000548100.1
zinc finger C3H1-type containing
chr21_-_42395943 0.07 ENST00000398405.5
transmembrane serine protease 3

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.1 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.3 1.0 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.2 1.5 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.2 0.2 GO:1904220 regulation of serine C-palmitoyltransferase activity(GO:1904220)
0.2 1.1 GO:0003025 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025) vagus nerve development(GO:0021564)
0.2 4.5 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.1 0.4 GO:0044278 cell wall disruption in other organism(GO:0044278)
0.1 0.4 GO:0048058 compound eye corneal lens development(GO:0048058)
0.1 0.4 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.1 2.0 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.1 0.4 GO:0060739 mesenchymal-epithelial cell signaling involved in prostate gland development(GO:0060739)
0.1 0.4 GO:0070981 L-asparagine biosynthetic process(GO:0070981) L-asparagine metabolic process(GO:0070982)
0.1 1.1 GO:0001554 luteolysis(GO:0001554)
0.1 0.8 GO:0007000 nucleolus organization(GO:0007000)
0.1 1.7 GO:0032329 serine transport(GO:0032329)
0.1 0.6 GO:0008218 bioluminescence(GO:0008218)
0.1 0.7 GO:0072734 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.1 0.3 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.1 0.4 GO:0003350 pulmonary myocardium development(GO:0003350)
0.1 0.6 GO:0048241 epinephrine transport(GO:0048241)
0.1 0.5 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1 0.4 GO:0072573 propionate metabolic process(GO:0019541) cellular response to progesterone stimulus(GO:0071393) tolerance induction to lipopolysaccharide(GO:0072573)
0.1 0.7 GO:0070294 renal sodium ion absorption(GO:0070294)
0.1 0.4 GO:0046208 spermine catabolic process(GO:0046208)
0.1 0.2 GO:0009106 lipoate metabolic process(GO:0009106)
0.1 0.7 GO:0006857 oligopeptide transport(GO:0006857)
0.1 0.4 GO:0035803 egg coat formation(GO:0035803)
0.1 0.2 GO:1903015 regulation of exo-alpha-sialidase activity(GO:1903015)
0.1 0.7 GO:0034141 positive regulation of toll-like receptor 3 signaling pathway(GO:0034141)
0.1 0.2 GO:0009386 translational attenuation(GO:0009386)
0.1 0.8 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.1 0.2 GO:1901253 negative regulation of intracellular transport of viral material(GO:1901253)
0.1 0.6 GO:0002934 desmosome organization(GO:0002934)
0.0 0.5 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551)
0.0 0.3 GO:0010734 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.0 0.1 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.0 0.7 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.0 0.6 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.2 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.0 0.1 GO:1903722 regulation of centriole elongation(GO:1903722)
0.0 0.2 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.0 0.2 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.0 1.3 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.0 GO:0031990 mRNA export from nucleus in response to heat stress(GO:0031990)
0.0 0.2 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 0.3 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.0 0.4 GO:2001204 regulation of osteoclast development(GO:2001204)
0.0 0.9 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.1 GO:0010193 response to ozone(GO:0010193)
0.0 0.3 GO:0021702 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.2 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.4 GO:2000773 negative regulation of cellular senescence(GO:2000773)
0.0 0.2 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.0 0.1 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.0 0.9 GO:0050832 defense response to fungus(GO:0050832)
0.0 0.2 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.2 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.3 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.2 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.4 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.0 0.1 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.1 GO:0043606 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.0 0.3 GO:0042737 drug catabolic process(GO:0042737)
0.0 2.8 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.2 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.0 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.0 0.1 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.0 0.1 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.2 GO:0039530 MDA-5 signaling pathway(GO:0039530)
0.0 0.2 GO:0007135 meiosis II(GO:0007135)
0.0 0.0 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.0 0.2 GO:0033008 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.0 0.1 GO:0051563 microglia differentiation(GO:0014004) microglia development(GO:0014005) collateral sprouting in absence of injury(GO:0048669) smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563) cellular response to norepinephrine stimulus(GO:0071874)
0.0 0.1 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
0.0 0.2 GO:0051256 mitotic spindle midzone assembly(GO:0051256)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.5 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 0.2 GO:0043159 acrosomal matrix(GO:0043159)
0.0 0.6 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 1.0 GO:0005614 interstitial matrix(GO:0005614)
0.0 4.7 GO:0005901 caveola(GO:0005901)
0.0 1.6 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.2 GO:0061617 MICOS complex(GO:0061617)
0.0 1.1 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.2 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.3 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.2 GO:0070081 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0 0.3 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 0.4 GO:0042588 zymogen granule(GO:0042588)
0.0 0.1 GO:0032279 asymmetric synapse(GO:0032279)
0.0 0.2 GO:0060091 kinocilium(GO:0060091)
0.0 0.3 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 1.1 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.2 GO:0097486 multivesicular body lumen(GO:0097486)
0.0 0.4 GO:0030057 desmosome(GO:0030057)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 4.2 GO:0033691 sialic acid binding(GO:0033691)
0.2 1.5 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.1 0.6 GO:0005277 acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
0.1 0.4 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797)
0.1 0.7 GO:0022897 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.1 0.4 GO:0052901 polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
0.1 0.4 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
0.1 0.8 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.1 0.5 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 0.2 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.1 3.2 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 0.2 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.1 0.4 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.0 0.3 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.2 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.0 0.2 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.2 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.0 0.2 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.4 GO:0045545 syndecan binding(GO:0045545)
0.0 0.4 GO:0032190 acrosin binding(GO:0032190)
0.0 0.1 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 0.3 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.2 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.4 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.2 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 1.3 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.4 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.2 GO:0004738 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.0 0.2 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.6 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.1 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.0 0.2 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.2 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.7 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.5 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.5 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.4 GO:0005537 mannose binding(GO:0005537)
0.0 0.1 GO:0050473 prostaglandin-endoperoxide synthase activity(GO:0004666) arachidonate 15-lipoxygenase activity(GO:0050473)
0.0 0.1 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0 0.3 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 2.8 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.4 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.1 GO:0016841 ammonia-lyase activity(GO:0016841)
0.0 0.2 GO:0031433 telethonin binding(GO:0031433)
0.0 0.1 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.1 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.0 0.1 GO:0004370 glycerol kinase activity(GO:0004370)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 4.5 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 1.5 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 1.7 ST GAQ PATHWAY G alpha q Pathway
0.0 0.7 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 1.4 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.5 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.7 PID PI3KCI PATHWAY Class I PI3K signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.5 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.6 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.5 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 2.0 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0 0.4 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.6 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.4 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 1.7 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 2.5 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.2 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.2 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.2 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 3.0 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.0 0.2 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon