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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for PDX1

Z-value: 0.48

Motif logo

Transcription factors associated with PDX1

Gene Symbol Gene ID Gene Info
ENSG00000139515.6 PDX1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PDX1hg38_v1_chr13_+_27919993_27920031-0.404.6e-02Click!

Activity profile of PDX1 motif

Sorted Z-values of PDX1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of PDX1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr15_+_74788542 0.82 ENST00000567571.5
C-terminal Src kinase
chr9_-_16728165 0.69 ENST00000603713.5
ENST00000603313.5
basonuclin 2
chr1_+_160190567 0.64 ENST00000368078.8
calsequestrin 1
chr4_+_85604146 0.63 ENST00000512201.5
Rho GTPase activating protein 24
chr15_-_55270280 0.62 ENST00000564609.5
RAB27A, member RAS oncogene family
chr12_-_16608183 0.61 ENST00000354662.5
ENST00000538051.5
LIM domain only 3
chr7_-_24980148 0.61 ENST00000313367.7
oxysterol binding protein like 3
chr12_-_16608073 0.60 ENST00000441439.6
LIM domain only 3
chr17_-_79950828 0.60 ENST00000572862.5
ENST00000573782.5
ENST00000574427.1
ENST00000570373.5
ENST00000340848.11
ENST00000576768.5
TBC1 domain family member 16
chr15_-_55270874 0.55 ENST00000567380.5
ENST00000565972.5
ENST00000569493.5
RAB27A, member RAS oncogene family
chr1_+_28259473 0.52 ENST00000253063.4
sestrin 2
chr15_-_55270383 0.52 ENST00000396307.6
RAB27A, member RAS oncogene family
chr20_-_51802433 0.51 ENST00000395997.3
spalt like transcription factor 4
chr8_+_32721823 0.51 ENST00000539990.3
ENST00000519240.5
neuregulin 1
chr8_-_10655137 0.49 ENST00000382483.4
RP1 like 1
chr18_+_58221535 0.49 ENST00000431212.6
ENST00000586268.5
ENST00000587190.5
NEDD4 like E3 ubiquitin protein ligase
chr5_-_143400716 0.48 ENST00000424646.6
ENST00000652686.1
nuclear receptor subfamily 3 group C member 1
chr8_+_49911604 0.47 ENST00000642164.1
ENST00000644093.1
ENST00000643999.1
ENST00000647073.1
ENST00000646880.1
syntrophin gamma 1
chr11_-_36598221 0.46 ENST00000311485.8
ENST00000527033.5
ENST00000532616.1
ENST00000618712.4
recombination activating 2
chr10_+_24208774 0.45 ENST00000376456.8
ENST00000458595.5
ENST00000376452.7
ENST00000430453.6
KIAA1217
chr18_+_59899988 0.45 ENST00000316660.7
ENST00000269518.9
phorbol-12-myristate-13-acetate-induced protein 1
chr4_+_94974984 0.43 ENST00000672698.1
bone morphogenetic protein receptor type 1B
chr8_+_49911801 0.43 ENST00000643809.1
syntrophin gamma 1
chr6_-_25042003 0.41 ENST00000510784.8
RHO family interacting cell polarization regulator 2
chr18_+_61333424 0.39 ENST00000262717.9
cadherin 20
chr4_-_138242325 0.37 ENST00000280612.9
solute carrier family 7 member 11
chr3_+_111998739 0.36 ENST00000393917.6
ENST00000273368.8
transgelin 3
chr18_-_36129305 0.35 ENST00000269187.10
ENST00000590986.5
ENST00000440549.6
solute carrier family 39 member 6
chr6_+_158017048 0.35 ENST00000638626.1
synaptojanin 2
chr3_+_111999189 0.35 ENST00000455401.6
transgelin 3
chr7_-_116030735 0.35 ENST00000393485.5
transcription factor EC
chr18_+_34593312 0.34 ENST00000591816.6
ENST00000588125.5
ENST00000684610.1
ENST00000683705.1
ENST00000598334.5
ENST00000588684.5
ENST00000554864.7
ENST00000399121.9
ENST00000595022.5
dystrobrevin alpha
chr19_-_14979848 0.34 ENST00000594383.2
solute carrier family 1 member 6
chr5_+_98773651 0.34 ENST00000513185.3
repulsive guidance molecule BMP co-receptor b
chr5_+_67004618 0.33 ENST00000261569.11
ENST00000436277.5
microtubule associated serine/threonine kinase family member 4
chr3_+_111998915 0.33 ENST00000478951.6
transgelin 3
chr12_-_21775581 0.31 ENST00000537950.1
ENST00000665145.1
potassium inwardly rectifying channel subfamily J member 8
chr7_-_81770122 0.31 ENST00000423064.7
hepatocyte growth factor
chr19_-_3557563 0.30 ENST00000389395.7
ENST00000355415.7
major facilitator superfamily domain containing 12
chr4_-_122456725 0.29 ENST00000226730.5
interleukin 2
chr18_+_58341038 0.29 ENST00000679791.1
NEDD4 like E3 ubiquitin protein ligase
chr16_-_18868218 0.28 ENST00000566328.2
SMG1 nonsense mediated mRNA decay associated PI3K related kinase
chr10_-_13707536 0.28 ENST00000632570.1
ENST00000477221.2
FERM domain containing 4A
chr6_-_87095059 0.27 ENST00000369582.6
ENST00000610310.3
ENST00000630630.2
ENST00000627148.3
ENST00000625577.1
glycoprotein hormones, alpha polypeptide
chr7_-_116030750 0.27 ENST00000265440.12
ENST00000320239.11
transcription factor EC
chr12_+_107318395 0.27 ENST00000420571.6
ENST00000280758.10
BTB domain containing 11
chr17_-_41009124 0.27 ENST00000391588.3
keratin associated protein 3-1
chr11_-_102625332 0.26 ENST00000260228.3
matrix metallopeptidase 20
chr5_+_136058849 0.26 ENST00000508076.5
transforming growth factor beta induced
chr1_-_182672232 0.25 ENST00000508450.5
regulator of G protein signaling 8
chr6_+_63521738 0.25 ENST00000648894.1
ENST00000639568.2
protein tyrosine phosphatase 4A1
chr12_+_26195313 0.25 ENST00000422622.3
sarcospan
chr12_-_53336342 0.25 ENST00000537210.2
ENST00000536324.4
Sp7 transcription factor
chr11_-_85719111 0.25 ENST00000529581.5
ENST00000533577.1
synaptotagmin like 2
chr14_+_100019375 0.25 ENST00000544450.6
Enah/Vasp-like
chr7_-_73624492 0.24 ENST00000414749.6
ENST00000429400.6
ENST00000434326.5
ENST00000313375.8
ENST00000354613.5
ENST00000453275.1
MLX interacting protein like
chr5_-_36301883 0.24 ENST00000502994.5
ENST00000515759.5
ENST00000296604.8
RAN binding protein 3 like
chr11_-_85719160 0.24 ENST00000389958.7
ENST00000527794.5
synaptotagmin like 2
chr8_+_49911396 0.24 ENST00000642720.2
syntrophin gamma 1
chr21_-_30881572 0.24 ENST00000332378.6
keratin associated protein 11-1
chr11_-_85719045 0.23 ENST00000533057.6
ENST00000533892.5
synaptotagmin like 2
chr16_+_6483379 0.23 ENST00000552089.5
RNA binding fox-1 homolog 1
chr1_+_27935022 0.23 ENST00000411604.5
ENST00000373888.8
sphingomyelin phosphodiesterase acid like 3B
chr2_+_90021567 0.23 ENST00000436451.2
immunoglobulin kappa variable 6D-21 (non-functional)
chr12_-_86256267 0.22 ENST00000620241.4
MGAT4 family member C
chr18_+_78979811 0.22 ENST00000537592.7
spalt like transcription factor 3
chr15_+_58987652 0.22 ENST00000348370.9
ENST00000559160.1
ring finger protein 111
chr12_+_26195543 0.22 ENST00000242729.7
sarcospan
chr7_+_129375643 0.22 ENST00000490911.5
adenosylhomocysteinase like 2
chr14_-_77423517 0.22 ENST00000555603.1
NADP dependent oxidoreductase domain containing 1
chr7_-_22194709 0.22 ENST00000458533.5
Rap guanine nucleotide exchange factor 5
chr2_-_89160329 0.21 ENST00000390256.2
immunoglobulin kappa variable 6-21 (non-functional)
chr2_-_179562576 0.21 ENST00000336917.9
zinc finger protein 385B
chr1_-_152414256 0.21 ENST00000271835.3
cornulin
chr17_+_44957907 0.20 ENST00000678938.1
N-myristoyltransferase 1
chr5_+_141484997 0.20 ENST00000617094.1
ENST00000306593.2
ENST00000610539.1
ENST00000618371.4
protocadherin gamma subfamily C, 4
chr6_+_131250375 0.20 ENST00000474850.2
A-kinase anchoring protein 7
chr12_+_80716906 0.20 ENST00000228644.4
myogenic factor 5
chr12_-_53335737 0.20 ENST00000303846.3
Sp7 transcription factor
chr20_+_44910045 0.20 ENST00000255136.8
ENST00000217073.7
poly(A) binding protein cytoplasmic 1 like
chr9_-_14722725 0.20 ENST00000380911.4
cerberus 1, DAN family BMP antagonist
chr4_-_52659238 0.20 ENST00000451218.6
ENST00000441222.8
ubiquitin specific peptidase 46
chr13_-_83882390 0.19 ENST00000377084.3
SLIT and NTRK like family member 1
chr18_+_34978244 0.19 ENST00000436190.6
microtubule associated protein RP/EB family member 2
chr15_+_62561361 0.19 ENST00000561311.5
talin 2
chr15_+_28885955 0.19 ENST00000558402.5
ENST00000683413.1
ENST00000558330.5
amyloid beta precursor protein binding family A member 2
chr18_+_34593392 0.19 ENST00000684377.1
dystrobrevin alpha
chr1_+_67685170 0.19 ENST00000370985.4
ENST00000370986.9
ENST00000650283.1
ENST00000648742.1
growth arrest and DNA damage inducible alpha
chr14_-_60649449 0.19 ENST00000645694.3
SIX homeobox 1
chr16_+_6483728 0.18 ENST00000675459.1
ENST00000551752.5
RNA binding fox-1 homolog 1
chr1_+_36155930 0.18 ENST00000316156.8
MAP7 domain containing 1
chr18_-_34224871 0.18 ENST00000261592.10
nucleolar protein 4
chr4_+_168092530 0.18 ENST00000359299.8
annexin A10
chr1_-_182671902 0.18 ENST00000483095.6
regulator of G protein signaling 8
chr12_+_53954870 0.18 ENST00000243103.4
homeobox C12
chr9_+_122370523 0.18 ENST00000643810.1
ENST00000540753.6
prostaglandin-endoperoxide synthase 1
chr1_-_182671853 0.18 ENST00000367556.5
regulator of G protein signaling 8
chr16_+_6483813 0.18 ENST00000675653.1
RNA binding fox-1 homolog 1
chr4_-_69653223 0.17 ENST00000286604.8
ENST00000505512.1
ENST00000514019.1
UDP glucuronosyltransferase family 2 member A1 complex locus
chrX_-_100874209 0.17 ENST00000372964.5
ENST00000217885.5
NADPH oxidase 1
chr8_+_76681208 0.17 ENST00000651372.2
zinc finger homeobox 4
chr11_-_26572254 0.17 ENST00000529533.6
mucin 15, cell surface associated
chr20_-_51802509 0.17 ENST00000371539.7
ENST00000217086.9
spalt like transcription factor 4
chr5_-_141619049 0.17 ENST00000647433.1
ENST00000253811.10
ENST00000389057.9
ENST00000398557.8
diaphanous related formin 1
chr18_+_34709356 0.16 ENST00000585446.1
ENST00000681241.1
dystrobrevin alpha
chr5_-_141618957 0.16 ENST00000389054.8
diaphanous related formin 1
chr15_+_33968484 0.16 ENST00000383263.7
cholinergic receptor muscarinic 5
chr6_-_166627244 0.16 ENST00000265678.9
ribosomal protein S6 kinase A2
chr14_-_68794597 0.16 ENST00000336440.3
ZFP36 ring finger protein like 1
chr1_+_100538131 0.16 ENST00000315033.5
G protein-coupled receptor 88
chr5_-_141618914 0.16 ENST00000518047.5
diaphanous related formin 1
chr8_+_10095704 0.15 ENST00000382490.9
methionine sulfoxide reductase A
chr13_-_46142834 0.15 ENST00000674665.1
lymphocyte cytosolic protein 1
chr11_-_26572102 0.15 ENST00000455601.6
mucin 15, cell surface associated
chr5_-_124746630 0.14 ENST00000513986.2
zinc finger protein 608
chr8_+_10095551 0.14 ENST00000522907.5
ENST00000528246.5
methionine sulfoxide reductase A
chr1_+_50108856 0.14 ENST00000650764.1
ENST00000494555.2
ENST00000371824.7
ENST00000371823.8
ENST00000652693.1
ELAV like RNA binding protein 4
chr2_-_190062721 0.14 ENST00000260950.5
myostatin
chr15_-_100341899 0.13 ENST00000568565.2
ENST00000268070.9
ADAM metallopeptidase with thrombospondin type 1 motif 17
chr8_-_42377227 0.13 ENST00000220812.3
dickkopf WNT signaling pathway inhibitor 4
chr7_-_100119840 0.13 ENST00000437822.6
TATA-box binding protein associated factor 6
chr3_-_101320558 0.13 ENST00000193391.8
interphotoreceptor matrix proteoglycan 2
chr4_-_115113614 0.12 ENST00000264363.7
N-deacetylase and N-sulfotransferase 4
chr21_-_30166782 0.12 ENST00000286808.5
claudin 17
chr14_-_94770102 0.12 ENST00000238558.5
goosecoid homeobox
chr15_+_41621492 0.12 ENST00000570161.6
MAX dimerization protein MGA
chr1_+_107141022 0.12 ENST00000370067.5
ENST00000370068.6
netrin G1
chr19_+_15082211 0.12 ENST00000641398.1
olfactory receptor family 1 subfamily I member 1
chr17_-_7080275 0.12 ENST00000571664.1
ENST00000254868.8
C-type lectin domain containing 10A
chr7_-_151519891 0.12 ENST00000262187.10
Ras homolog, mTORC1 binding
chr6_-_119149124 0.12 ENST00000368475.8
family with sequence similarity 184 member A
chr12_-_121016345 0.12 ENST00000535367.1
ENST00000538296.5
ENST00000288757.7
ENST00000539736.5
ENST00000537817.5
chromosome 12 open reading frame 43
chr4_-_39977836 0.12 ENST00000303538.13
ENST00000503396.5
PDS5 cohesin associated factor A
chr17_-_7080231 0.12 ENST00000576617.5
ENST00000416562.7
C-type lectin domain containing 10A
chr3_-_167474026 0.11 ENST00000466903.1
ENST00000264677.8
serpin family I member 2
chr13_-_83882456 0.11 ENST00000674365.1
SLIT and NTRK like family member 1
chr2_+_157257687 0.11 ENST00000259056.5
polypeptide N-acetylgalactosaminyltransferase 5
chr20_+_61599755 0.11 ENST00000543233.2
cadherin 4
chr7_-_101217569 0.11 ENST00000223127.8
procollagen-lysine,2-oxoglutarate 5-dioxygenase 3
chr16_-_29899245 0.11 ENST00000537485.5
seizure related 6 homolog like 2
chr11_+_124183219 0.11 ENST00000641351.2
olfactory receptor family 10 subfamily D member 3
chr7_+_114414997 0.11 ENST00000462331.5
ENST00000393491.7
ENST00000403559.8
ENST00000408937.7
ENST00000393498.6
ENST00000393495.7
ENST00000378237.7
forkhead box P2
chr12_-_86256299 0.11 ENST00000552808.6
ENST00000547225.5
MGAT4 family member C
chr4_+_118888918 0.10 ENST00000434046.6
synaptopodin 2
chr4_+_150582119 0.10 ENST00000317605.6
mab-21 like 2
chr12_+_41437680 0.10 ENST00000649474.1
ENST00000539469.6
ENST00000298919.7
PDZ domain containing ring finger 4
chr11_+_13962676 0.10 ENST00000576479.4
spondin 1
chr4_-_115113822 0.10 ENST00000613194.4
N-deacetylase and N-sulfotransferase 4
chr20_+_44355692 0.10 ENST00000316673.8
ENST00000609795.5
ENST00000457232.5
ENST00000609262.5
hepatocyte nuclear factor 4 alpha
chr3_-_38029604 0.10 ENST00000334661.5
phospholipase C delta 1
chr13_+_101452569 0.10 ENST00000618057.4
integrin subunit beta like 1
chr3_+_122055355 0.10 ENST00000330540.7
ENST00000469710.5
ENST00000493101.5
CD86 molecule
chr6_-_27912396 0.10 ENST00000303324.4
olfactory receptor family 2 subfamily B member 2
chr4_-_41748713 0.10 ENST00000226382.4
paired like homeobox 2B
chr19_-_55599493 0.09 ENST00000221665.5
ENST00000592585.1
FLT3 interacting zinc finger 1
chr14_-_56805648 0.09 ENST00000554788.5
ENST00000554845.1
ENST00000408990.8
orthodenticle homeobox 2
chrX_+_134796758 0.09 ENST00000414371.6
PABIR family member 3
chr11_+_31816266 0.09 ENST00000644607.1
ENST00000646221.1
ENST00000643671.1
ENST00000643931.1
ENST00000642614.1
ENST00000642818.1
ENST00000645848.1
ENST00000506388.2
ENST00000645824.1
ENST00000532942.5
PAX6 upstream antisense RNA
novel protein
chr11_+_15114912 0.09 ENST00000379556.8
INSC spindle orientation adaptor protein
chr15_+_41621134 0.09 ENST00000566718.6
MAX dimerization protein MGA
chr17_-_66229380 0.09 ENST00000205948.11
apolipoprotein H
chr15_-_65115185 0.09 ENST00000559089.6
ubiquitin associated protein 1 like
chr6_-_116060859 0.09 ENST00000606080.2
fyn related Src family tyrosine kinase
chr1_+_158461574 0.09 ENST00000641432.1
ENST00000641460.1
ENST00000641535.1
ENST00000641971.1
olfactory receptor family 10 subfamily K member 1
chr3_-_57199938 0.09 ENST00000473921.2
ENST00000295934.8
HESX homeobox 1
chrX_-_13817027 0.09 ENST00000493677.5
ENST00000355135.6
ENST00000316715.9
glycoprotein M6B
chr12_+_80707625 0.08 ENST00000228641.4
myogenic factor 6
chr12_+_49227874 0.08 ENST00000541364.5
tubulin alpha 1c
chr4_+_56907876 0.08 ENST00000640168.2
ENST00000309042.12
RE1 silencing transcription factor
chr15_-_72271244 0.08 ENST00000287196.13
poly(ADP-ribose) polymerase family member 6
chr5_+_172641241 0.08 ENST00000369800.6
ENST00000520919.5
ENST00000522853.5
neuralized E3 ubiquitin protein ligase 1B
chr9_-_5339874 0.08 ENST00000223862.2
relaxin 1
chr3_+_108822778 0.08 ENST00000295756.11
T cell receptor associated transmembrane adaptor 1
chr8_+_91249307 0.08 ENST00000309536.6
ENST00000276609.8
solute carrier family 26 member 7
chr4_+_1289870 0.08 ENST00000505177.6
ENST00000503653.5
ENST00000264750.10
ENST00000303400.9
ENST00000502558.5
ENST00000514708.5
macrophage erythroblast attacher, E3 ubiquitin ligase
chr7_+_114414809 0.08 ENST00000350908.9
forkhead box P2
chr11_-_115504389 0.08 ENST00000545380.5
ENST00000452722.7
ENST00000331581.11
ENST00000537058.5
ENST00000536727.5
ENST00000542447.6
cell adhesion molecule 1
chr7_+_70596078 0.08 ENST00000644506.1
activator of transcription and developmental regulator AUTS2
chr3_-_74521140 0.08 ENST00000263665.6
contactin 3
chr15_+_51377247 0.08 ENST00000396399.6
gliomedin
chr3_+_108822759 0.08 ENST00000426646.1
T cell receptor associated transmembrane adaptor 1
chr10_+_116324440 0.08 ENST00000333254.4
coiled-coil domain containing 172
chr7_-_81770039 0.07 ENST00000222390.11
ENST00000453411.6
ENST00000457544.7
ENST00000444829.7
hepatocyte growth factor
chr3_-_179604628 0.07 ENST00000476781.6
ENST00000259038.6
mitochondrial ribosomal protein L47
chr12_-_108827384 0.07 ENST00000326470.9
slingshot protein phosphatase 1
chr3_+_35680994 0.07 ENST00000441454.5
cAMP regulated phosphoprotein 21
chr3_-_179604648 0.07 ENST00000392659.2
mitochondrial ribosomal protein L47
chr4_-_154612635 0.07 ENST00000407946.5
ENST00000405164.5
ENST00000336098.8
ENST00000393846.6
ENST00000404648.7
ENST00000443553.5
fibrinogen gamma chain
chr17_-_10026265 0.07 ENST00000437099.6
ENST00000396115.6
growth arrest specific 7
chr6_+_167122742 0.06 ENST00000341935.9
ENST00000349984.6
C-C motif chemokine receptor 6
chr6_-_41734160 0.06 ENST00000424495.2
ENST00000420312.6
transcription factor EB
chr4_-_8871817 0.06 ENST00000400677.5
H6 family homeobox 1
chr19_-_49423441 0.06 ENST00000270631.2
parathyroid hormone 2
chr3_+_115623502 0.06 ENST00000305124.11
ENST00000393780.3
growth associated protein 43
chr7_-_151520080 0.06 ENST00000496004.5
Ras homolog, mTORC1 binding
chr10_+_73785571 0.06 ENST00000604729.6
ENST00000603114.5
ENST00000398706.6
ENST00000604524.5
ENST00000605216.5
zinc finger SWIM-type containing 8
chr1_-_149886652 0.06 ENST00000369155.3
H2B clustered histone 21
chr15_+_92900189 0.06 ENST00000626874.2
ENST00000627622.1
ENST00000629346.2
ENST00000628375.2
ENST00000420239.7
ENST00000394196.9
chromodomain helicase DNA binding protein 2
chr2_+_48314637 0.06 ENST00000413569.5
ENST00000340553.8
forkhead box N2
chr12_+_55549602 0.06 ENST00000641569.1
ENST00000641851.1
olfactory receptor family 6 subfamily C member 4

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.7 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.2 1.2 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.2 0.5 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.1 0.8 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.1 0.5 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.1 0.4 GO:1903904 negative regulation of establishment of T cell polarity(GO:1903904) negative regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001107)
0.1 0.8 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1 0.2 GO:0021758 caudate nucleus development(GO:0021757) putamen development(GO:0021758)
0.1 0.4 GO:1902731 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) negative regulation of chondrocyte proliferation(GO:1902731)
0.1 0.2 GO:2000729 positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.1 0.5 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.1 0.2 GO:1990451 cellular stress response to acidic pH(GO:1990451)
0.1 0.3 GO:0070778 L-aspartate transport(GO:0070778) L-aspartate transmembrane transport(GO:0089712)
0.1 0.4 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1 0.2 GO:1904580 regulation of intracellular mRNA localization(GO:1904580) positive regulation of intracellular mRNA localization(GO:1904582)
0.1 0.7 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.1 0.2 GO:0018008 N-terminal peptidyl-glycine N-myristoylation(GO:0018008)
0.0 0.2 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.0 0.6 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.7 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.1 GO:0014034 neural crest cell fate commitment(GO:0014034)
0.0 0.5 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.0 0.3 GO:2000320 negative regulation of T-helper 17 type immune response(GO:2000317) negative regulation of T-helper 17 cell differentiation(GO:2000320)
0.0 0.1 GO:0032761 negative regulation of T cell tolerance induction(GO:0002665) negative regulation of T cell anergy(GO:0002668) negative regulation of lymphocyte anergy(GO:0002912) regulation of lymphotoxin A production(GO:0032681) positive regulation of lymphotoxin A production(GO:0032761) regulation of lymphotoxin A biosynthetic process(GO:0043016) positive regulation of lymphotoxin A biosynthetic process(GO:0043017)
0.0 0.5 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.1 GO:0003358 noradrenergic neuron development(GO:0003358)
0.0 0.2 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.2 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.6 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.1 GO:2000797 amniotic stem cell differentiation(GO:0097086) negative regulation of dense core granule biogenesis(GO:2000706) negative regulation of mesenchymal stem cell differentiation(GO:2000740) regulation of amniotic stem cell differentiation(GO:2000797) negative regulation of amniotic stem cell differentiation(GO:2000798)
0.0 0.2 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.4 GO:0010917 negative regulation of mitochondrial membrane potential(GO:0010917)
0.0 0.1 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631) negative regulation of satellite cell differentiation(GO:1902725)
0.0 0.1 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.0 0.1 GO:0051799 negative regulation of hair follicle development(GO:0051799)
0.0 0.2 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.2 GO:0061743 motor learning(GO:0061743)
0.0 0.3 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.0 0.1 GO:0014016 proximal/distal axis specification(GO:0009946) neuroblast differentiation(GO:0014016)
0.0 0.3 GO:0030091 protein repair(GO:0030091)
0.0 0.2 GO:0006561 proline biosynthetic process(GO:0006561)
0.0 0.1 GO:1904717 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.0 0.3 GO:0070166 enamel mineralization(GO:0070166)
0.0 0.3 GO:0060013 righting reflex(GO:0060013)
0.0 0.4 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.3 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.2 GO:0090324 negative regulation of oxidative phosphorylation(GO:0090324)
0.0 0.7 GO:0043586 tongue development(GO:0043586)
0.0 0.2 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.2 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.2 GO:0030210 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0 0.2 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
0.0 0.2 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.1 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.0 0.0 GO:0051885 regulation of anagen(GO:0051884) positive regulation of anagen(GO:0051885)
0.0 0.6 GO:0001919 regulation of receptor recycling(GO:0001919)
0.0 0.1 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.4 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 0.2 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.0 0.1 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.0 0.7 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.1 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.6 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.0 0.2 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.2 GO:0033033 negative regulation of myeloid cell apoptotic process(GO:0033033)
0.0 0.0 GO:0019082 viral protein processing(GO:0019082) negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.0 0.0 GO:0002554 response to molecule of fungal origin(GO:0002238) serotonin production involved in inflammatory response(GO:0002351) serotonin secretion involved in inflammatory response(GO:0002442) serotonin secretion by platelet(GO:0002554) positive regulation of interleukin-3 production(GO:0032752) interleukin-3 biosynthetic process(GO:0042223) beta selection(GO:0043366) regulation of interleukin-3 biosynthetic process(GO:0045399) positive regulation of interleukin-3 biosynthetic process(GO:0045401) cellular response to molecule of fungal origin(GO:0071226)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0014802 terminal cisterna(GO:0014802)
0.1 1.4 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 1.1 GO:0016013 syntrophin complex(GO:0016013)
0.1 0.5 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.4 GO:0060171 stereocilium membrane(GO:0060171)
0.0 0.3 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.4 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.6 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.1 GO:0034657 GID complex(GO:0034657)
0.0 0.1 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.0 0.5 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.5 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.6 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.2 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.5 GO:0030673 axolemma(GO:0030673)
0.0 0.0 GO:0005592 collagen type XI trimer(GO:0005592)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0038051 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.1 0.4 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.1 0.5 GO:0070728 leucine binding(GO:0070728)
0.1 0.3 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.1 1.7 GO:0031489 myosin V binding(GO:0031489)
0.1 0.3 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.1 0.3 GO:0017098 sulfonylurea receptor binding(GO:0017098)
0.1 0.2 GO:0004379 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
0.0 0.3 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 0.3 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.2 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.2 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.4 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.2 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.0 0.4 GO:0043813 phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813)
0.0 0.8 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.2 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.2 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.7 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.8 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.5 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.1 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823) procollagen galactosyltransferase activity(GO:0050211)
0.0 0.4 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.0 0.2 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.1 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.0 0.2 GO:0016015 morphogen activity(GO:0016015)
0.0 0.2 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.1 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.0 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.0 0.7 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.6 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.2 GO:0005522 profilin binding(GO:0005522)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 PID BMP PATHWAY BMP receptor signaling
0.0 0.5 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.9 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.8 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.3 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.4 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.4 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.4 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.5 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.6 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.3 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.3 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle