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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for PGR

Z-value: 0.68

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Transcription factors associated with PGR

Gene Symbol Gene ID Gene Info
ENSG00000082175.15 PGR

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PGRhg38_v1_chr11_-_101129042_101129070,
hg38_v1_chr11_-_101129706_101129735
0.414.4e-02Click!

Activity profile of PGR motif

Sorted Z-values of PGR motif

Network of associatons between targets according to the STRING database.

First level regulatory network of PGR

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr3_-_149333407 1.84 ENST00000470080.5
transmembrane 4 L six family member 18
chr17_-_44199206 1.66 ENST00000589805.1
ataxin 7 like 3
chr12_+_78864768 1.62 ENST00000261205.9
ENST00000457153.6
synaptotagmin 1
chr9_-_104928139 1.45 ENST00000423487.6
ENST00000374733.1
ENST00000374736.8
ENST00000678995.1
ATP binding cassette subfamily A member 1
chr1_+_148748774 1.34 ENST00000322209.5
nudix hydrolase 4B
chr6_-_75493629 1.30 ENST00000393004.6
filamin A interacting protein 1
chr1_+_25616780 1.30 ENST00000374332.9
mannosidase alpha class 1C member 1
chr4_-_185775271 1.29 ENST00000430503.5
ENST00000319454.10
ENST00000450341.5
sorbin and SH3 domain containing 2
chr2_+_172821575 1.29 ENST00000397087.7
Rap guanine nucleotide exchange factor 4
chr2_-_187448244 1.20 ENST00000392370.8
ENST00000410068.5
ENST00000447403.5
ENST00000410102.5
calcitonin receptor like receptor
chr5_-_95081482 1.14 ENST00000312216.12
ENST00000512425.5
ENST00000505208.5
ENST00000429576.6
ENST00000508509.5
ENST00000510732.5
multiple C2 and transmembrane domain containing 1
chr4_-_185775890 1.12 ENST00000437304.6
sorbin and SH3 domain containing 2
chr6_-_75493773 1.08 ENST00000237172.12
filamin A interacting protein 1
chr3_-_149333619 1.07 ENST00000296059.7
transmembrane 4 L six family member 18
chr4_-_89838289 1.03 ENST00000336904.7
synuclein alpha
chr15_+_31366138 1.00 ENST00000558844.1
Kruppel like factor 13
chr12_+_78863962 0.99 ENST00000393240.7
synaptotagmin 1
chr18_+_44700796 0.98 ENST00000677130.1
SET binding protein 1
chr6_-_75206044 0.85 ENST00000322507.13
collagen type XII alpha 1 chain
chr22_-_28712136 0.82 ENST00000464581.6
checkpoint kinase 2
chr6_-_36839434 0.76 ENST00000244751.7
ENST00000633280.1
copine 5
chr5_-_88731827 0.72 ENST00000627170.2
myocyte enhancer factor 2C
chr11_+_6876625 0.71 ENST00000379829.2
olfactory receptor family 10 subfamily A member 4
chr16_-_10559135 0.70 ENST00000536829.1
epithelial membrane protein 2
chr9_+_2159672 0.69 ENST00000634343.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr12_+_7061206 0.67 ENST00000423384.5
ENST00000413211.5
complement C1s
chr20_+_36091409 0.62 ENST00000202028.9
erythrocyte membrane protein band 4.1 like 1
chr3_+_52420955 0.61 ENST00000465863.1
PHD finger protein 7
chr6_+_73695779 0.61 ENST00000422508.6
ENST00000437994.6
CD109 molecule
chr9_+_113463697 0.58 ENST00000317613.10
regulator of G protein signaling 3
chr14_-_34713759 0.58 ENST00000673315.1
cofilin 2
chr8_-_30083053 0.57 ENST00000256255.11
ENST00000523761.1
store-operated calcium entry associated regulatory factor
chr8_-_30083110 0.57 ENST00000545648.2
store-operated calcium entry associated regulatory factor
chr9_+_2159850 0.57 ENST00000416751.2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chrX_-_45200895 0.57 ENST00000377934.4
divergent protein kinase domain 2B
chrX_-_101386166 0.57 ENST00000308731.8
ENST00000372880.5
Bruton tyrosine kinase
chr1_-_85404494 0.56 ENST00000633113.1
dimethylarginine dimethylaminohydrolase 1
chrX_+_54807599 0.55 ENST00000375053.6
ENST00000627068.2
ENST00000375068.6
ENST00000347546.8
MAGE family member D2
chr2_-_182522703 0.55 ENST00000410103.1
phosphodiesterase 1A
chr18_-_55586092 0.55 ENST00000563888.6
ENST00000540999.5
ENST00000627685.2
transcription factor 4
chr2_-_215436061 0.55 ENST00000421182.5
ENST00000432072.6
ENST00000323926.10
ENST00000336916.8
ENST00000357867.8
ENST00000359671.5
ENST00000446046.5
ENST00000354785.11
ENST00000356005.8
ENST00000443816.5
ENST00000426059.1
fibronectin 1
chr20_-_23086316 0.55 ENST00000246006.5
CD93 molecule
chr7_+_130486171 0.53 ENST00000341441.9
ENST00000416162.7
mesoderm specific transcript
chr19_+_30372364 0.51 ENST00000355537.4
zinc finger protein 536
chr10_+_47322450 0.51 ENST00000581492.3
growth differentiation factor 2
chr20_-_25339731 0.49 ENST00000450393.5
ENST00000491682.5
abhydrolase domain containing 12, lysophospholipase
chr8_+_22589240 0.48 ENST00000450780.6
ENST00000430850.6
ENST00000447849.2
ENST00000614502.4
ENST00000443561.3
novel protein
PDZ and LIM domain 2
chr5_+_141417659 0.48 ENST00000398594.4
protocadherin gamma subfamily B, 7
chr9_-_15510954 0.48 ENST00000380733.9
PC4 and SFRS1 interacting protein 1
chr6_-_46954922 0.47 ENST00000265417.7
adhesion G protein-coupled receptor F5
chr12_-_71157992 0.45 ENST00000247829.8
tetraspanin 8
chr2_-_182242031 0.45 ENST00000358139.6
phosphodiesterase 1A
chr1_+_92168915 0.45 ENST00000637221.2
BTB domain containing 8
chr18_-_55351977 0.43 ENST00000643689.1
transcription factor 4
chr1_-_110391041 0.43 ENST00000369781.8
ENST00000437429.6
ENST00000541986.5
solute carrier family 16 member 4
chr12_-_6606427 0.43 ENST00000642879.1
chromodomain helicase DNA binding protein 4
chr12_-_71157872 0.42 ENST00000546561.2
tetraspanin 8
chrX_-_45200828 0.42 ENST00000398000.7
divergent protein kinase domain 2B
chrX_+_101488044 0.42 ENST00000423738.4
armadillo repeat containing X-linked 4
chr6_+_73696145 0.41 ENST00000287097.6
CD109 molecule
chr12_-_6606642 0.40 ENST00000545584.2
ENST00000545942.6
chromodomain helicase DNA binding protein 4
chr2_-_74440484 0.40 ENST00000305557.9
ENST00000233330.6
rhotekin
chr9_+_113536497 0.40 ENST00000462143.5
regulator of G protein signaling 3
chrX_-_112840815 0.39 ENST00000304758.5
ENST00000371959.9
angiomotin
chr19_+_51693327 0.38 ENST00000637797.2
sperm acrosome associated 6
chr12_-_6606320 0.38 ENST00000642594.1
ENST00000644289.1
ENST00000645095.1
chromodomain helicase DNA binding protein 4
chr13_-_99016034 0.38 ENST00000448493.7
dedicator of cytokinesis 9
chr7_+_143959927 0.37 ENST00000624504.1
olfactory receptor family 2 subfamily F member 1
chr19_+_13024917 0.37 ENST00000587260.1
nuclear factor I X
chr17_+_76001715 0.36 ENST00000586261.2
cyclin dependent kinase 3
chr3_-_114624193 0.36 ENST00000481632.5
zinc finger and BTB domain containing 20
chrX_+_15507302 0.35 ENST00000342014.6
BMX non-receptor tyrosine kinase
chr6_-_154510675 0.35 ENST00000607772.6
CNKSR family member 3
chr9_-_15510991 0.34 ENST00000380715.5
ENST00000380716.8
ENST00000380738.8
PC4 and SFRS1 interacting protein 1
chr17_-_7857139 0.34 ENST00000576384.1
N-alpha-acetyltransferase 38, NatC auxiliary subunit
chr17_-_44389594 0.34 ENST00000262407.6
integrin subunit alpha 2b
chr14_+_65411845 0.34 ENST00000556518.5
ENST00000557164.5
fucosyltransferase 8
chr16_-_28495519 0.33 ENST00000569430.7
CLN3 lysosomal/endosomal transmembrane protein, battenin
chr14_-_34713788 0.33 ENST00000341223.8
cofilin 2
chr17_-_73092657 0.33 ENST00000580557.5
ENST00000579732.5
ENST00000578620.1
ENST00000542342.6
ENST00000255559.7
ENST00000579018.5
solute carrier family 39 member 11
chr5_+_175871670 0.33 ENST00000514150.5
complexin 2
chr17_+_19282979 0.33 ENST00000395626.5
ENST00000571254.1
epsin 2
chr2_-_55334529 0.33 ENST00000645860.1
ENST00000642563.1
ENST00000647396.1
coiled-coil domain containing 88A
chr8_+_81732434 0.32 ENST00000297265.5
charged multivesicular body protein 4C
chr1_-_155991198 0.32 ENST00000673475.1
Rho/Rac guanine nucleotide exchange factor 2
chr2_+_190343561 0.32 ENST00000322522.8
ENST00000392329.7
ENST00000430311.5
inositol polyphosphate-1-phosphatase
chrX_+_151694967 0.32 ENST00000448726.5
ENST00000538575.5
proline rich and Gla domain 3
chr17_-_7857461 0.31 ENST00000575771.6
ENST00000575071.5
N-alpha-acetyltransferase 38, NatC auxiliary subunit
chr3_+_148865288 0.31 ENST00000296046.4
carboxypeptidase A3
chr6_+_31655888 0.31 ENST00000375916.4
apolipoprotein M
chr3_+_25428233 0.29 ENST00000437042.6
ENST00000330688.9
retinoic acid receptor beta
chr14_+_24171853 0.29 ENST00000620473.4
ENST00000557806.5
ENST00000611366.5
REC8 meiotic recombination protein
chr2_+_162318884 0.28 ENST00000446271.5
ENST00000429691.6
grancalcin
chr8_-_7430348 0.28 ENST00000318124.3
defensin beta 103B
chr7_-_93226449 0.28 ENST00000394468.7
ENST00000453812.2
HEPACAM family member 2
chr15_+_65550819 0.28 ENST00000569894.5
3-hydroxyacyl-CoA dehydratase 3
chr6_-_159045010 0.28 ENST00000338313.5
T cell activation RhoGTPase activating protein
chr8_+_132919403 0.28 ENST00000519178.5
thyroglobulin
chr1_-_205321737 0.28 ENST00000367157.6
NUAK family kinase 2
chr5_+_139293660 0.27 ENST00000512876.5
ENST00000513678.5
matrin 3
chr15_+_73683938 0.26 ENST00000567189.5
CD276 molecule
chr20_-_61998132 0.26 ENST00000474089.5
TATA-box binding protein associated factor 4
chr10_-_77140757 0.25 ENST00000637862.2
potassium calcium-activated channel subfamily M alpha 1
chr8_+_10095704 0.25 ENST00000382490.9
methionine sulfoxide reductase A
chr7_-_130441136 0.25 ENST00000675596.1
ENST00000676312.1
centrosomal protein 41
chr2_+_10420021 0.24 ENST00000422133.1
hippocalcin like 1
chr14_-_67488709 0.24 ENST00000554480.6
transmembrane protein 229B
chr14_-_21476874 0.24 ENST00000649801.1
ENST00000397762.6
RAB2B, member RAS oncogene family
chr14_+_22516273 0.24 ENST00000390510.1
T cell receptor alpha joining 27
chr19_+_48874318 0.24 ENST00000600406.1
protein phosphatase 1 regulatory subunit 15A
chr12_+_57455266 0.24 ENST00000266646.3
inhibin subunit beta E
chr11_-_73982830 0.24 ENST00000536983.5
ENST00000663595.2
ENST00000310473.9
uncoupling protein 2
chr5_+_102865805 0.23 ENST00000346918.7
peptidylglycine alpha-amidating monooxygenase
chr5_-_135034212 0.23 ENST00000265340.12
paired like homeodomain 1
chr11_+_6481473 0.23 ENST00000530751.1
ENST00000254616.11
translocase of inner mitochondrial membrane 10B
chr12_-_108731505 0.23 ENST00000261401.8
ENST00000552871.5
coronin 1C
chr11_-_5441514 0.22 ENST00000380211.1
olfactory receptor family 51 subfamily I member 1
chr3_-_114624921 0.22 ENST00000393785.6
zinc finger and BTB domain containing 20
chr17_+_47209338 0.22 ENST00000393450.5
myosin light chain 4
chr5_+_66828762 0.22 ENST00000490016.6
ENST00000403666.5
ENST00000450827.5
microtubule associated serine/threonine kinase family member 4
chr19_-_49361475 0.22 ENST00000598810.5
TEA domain transcription factor 2
chr6_-_32190170 0.22 ENST00000375050.6
PBX homeobox 2
chr3_-_185821092 0.22 ENST00000421047.3
insulin like growth factor 2 mRNA binding protein 2
chrX_+_154429092 0.22 ENST00000619046.5
ATPase H+ transporting accessory protein 1
chr11_-_113706330 0.21 ENST00000540540.5
ENST00000538955.5
ENST00000545579.6
transmembrane serine protease 5
chr17_+_47209035 0.21 ENST00000572316.5
ENST00000354968.5
ENST00000576874.5
ENST00000536623.6
myosin light chain 4
chr3_+_111542134 0.21 ENST00000438817.6
CD96 molecule
chr5_+_139293939 0.21 ENST00000508689.1
ENST00000514528.5
matrin 3
chr2_-_157874976 0.21 ENST00000682025.1
ENST00000683487.1
ENST00000682300.1
ENST00000683441.1
ENST00000684595.1
ENST00000683426.1
ENST00000683820.1
ENST00000263640.7
activin A receptor type 1
chr2_+_96326204 0.21 ENST00000420728.1
ENST00000361124.5
ITPRIP like 1
chr5_-_38557459 0.20 ENST00000511561.1
LIF receptor subunit alpha
chr18_+_63777773 0.20 ENST00000447428.5
ENST00000546027.5
serpin family B member 7
chr17_+_47209375 0.20 ENST00000572303.1
myosin light chain 4
chr2_-_27308445 0.20 ENST00000296099.2
urocortin
chr12_+_8914464 0.20 ENST00000544916.6
polyhomeotic homolog 1
chr5_+_179820895 0.20 ENST00000504627.1
ENST00000389805.9
ENST00000510187.5
sequestosome 1
chr10_-_70382589 0.20 ENST00000373224.5
ENST00000446961.4
ENST00000357631.6
ENST00000358141.6
ENST00000395010.5
leucine rich repeat containing 20
chr7_+_74093079 0.20 ENST00000538333.3
LIM domain kinase 1
chrX_+_65588368 0.20 ENST00000609672.5
moesin
chr5_-_64768619 0.20 ENST00000513458.9
SREK1 interacting protein 1
chr8_-_101790934 0.20 ENST00000523645.5
ENST00000520346.1
ENST00000220931.11
ENST00000522448.5
ENST00000522951.5
ENST00000522252.5
ENST00000519098.5
neurocalcin delta
chr3_+_42091316 0.20 ENST00000327628.10
trafficking kinesin protein 1
chr8_+_40153475 0.19 ENST00000315792.5
transcriptional and immune response regulator
chr1_+_152719522 0.19 ENST00000368775.3
chromosome 1 open reading frame 68
chr13_+_73058993 0.19 ENST00000377687.6
Kruppel like factor 5
chr7_+_74027770 0.19 ENST00000445912.5
ENST00000621115.4
elastin
chr10_+_122271292 0.19 ENST00000260723.6
BTB domain containing 16
chr1_-_183590876 0.19 ENST00000367536.5
neutrophil cytosolic factor 2
chr12_-_48788995 0.19 ENST00000550422.5
ENST00000357869.8
adenylate cyclase 6
chr2_+_225399684 0.19 ENST00000636099.1
neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2
chr4_-_151015713 0.19 ENST00000357115.9
LPS responsive beige-like anchor protein
chr6_+_20401864 0.19 ENST00000346618.8
ENST00000613242.4
E2F transcription factor 3
chr15_-_43584864 0.18 ENST00000381885.5
ENST00000396923.7
diphosphoinositol pentakisphosphate kinase 1
chr3_+_159273235 0.18 ENST00000638749.1
IQCJ-SCHIP1 readthrough
chr5_+_70025534 0.18 ENST00000515588.1
small EDRK-rich factor 1B
chr8_+_10095551 0.18 ENST00000522907.5
ENST00000528246.5
methionine sulfoxide reductase A
chr22_-_40856565 0.18 ENST00000620312.4
ENST00000216218.8
ST13 Hsp70 interacting protein
chr4_+_127880876 0.18 ENST00000270861.10
ENST00000515069.5
ENST00000513090.5
ENST00000507249.5
polo like kinase 4
chr17_-_4560564 0.18 ENST00000574584.1
ENST00000381550.8
ENST00000301395.7
gamma-glutamyltransferase 6
chr12_+_56267674 0.18 ENST00000546544.5
ENST00000553234.1
coenzyme Q10A
chr11_-_625168 0.18 ENST00000349570.11
cadherin related family member 5
chr7_+_74028127 0.18 ENST00000438880.5
ENST00000414324.5
ENST00000380562.8
ENST00000380575.8
ENST00000380584.8
ENST00000458204.5
ENST00000357036.9
ENST00000417091.5
ENST00000429192.5
ENST00000252034.12
ENST00000442310.5
ENST00000380553.8
ENST00000380576.9
ENST00000428787.5
ENST00000320399.10
elastin
chr14_-_21580076 0.18 ENST00000641040.1
ENST00000641185.1
olfactory receptor family 10 subfamily G member 3
chr17_+_48892761 0.18 ENST00000355938.9
ENST00000393366.7
ENST00000503641.5
ENST00000514808.5
ENST00000506855.1
ATP synthase membrane subunit c locus 1
chr11_-_113706292 0.17 ENST00000544634.5
ENST00000539732.5
ENST00000538770.1
ENST00000536856.5
ENST00000299882.11
ENST00000544476.1
transmembrane serine protease 5
chr7_+_23598144 0.17 ENST00000410069.1
coiled-coil domain containing 126
chr17_-_35943662 0.17 ENST00000618542.4
lysozyme like 6
chr17_+_35809474 0.17 ENST00000604879.5
ENST00000603427.5
ENST00000603777.5
ENST00000605844.6
ENST00000604841.5
TATA-box binding protein associated factor 15
chr7_+_22727147 0.17 ENST00000426291.5
ENST00000401651.5
ENST00000258743.10
ENST00000407492.5
ENST00000401630.7
ENST00000406575.1
interleukin 6
chr13_+_101452629 0.17 ENST00000622834.4
ENST00000545560.6
ENST00000376180.8
integrin subunit beta like 1
chr10_+_113125536 0.17 ENST00000349937.7
transcription factor 7 like 2
chr17_-_35943707 0.17 ENST00000615905.5
lysozyme like 6
chr3_-_114624979 0.17 ENST00000676079.1
zinc finger and BTB domain containing 20
chr1_-_32336224 0.17 ENST00000329421.8
MARCKS like 1
chr3_-_151384741 0.16 ENST00000302632.4
purinergic receptor P2Y12
chr4_-_57110373 0.16 ENST00000295666.6
ENST00000514062.2
insulin like growth factor binding protein 7
chrX_-_79367307 0.16 ENST00000373298.7
integral membrane protein 2A
chrX_+_16946862 0.15 ENST00000303843.7
RALBP1 associated Eps domain containing 2
chr1_-_26067622 0.15 ENST00000374272.4
tripartite motif containing 63
chr17_-_3433841 0.15 ENST00000248384.1
olfactory receptor family 1 subfamily E member 2
chr9_+_124853417 0.15 ENST00000613760.4
ENST00000618744.4
ENST00000373574.2
WD repeat domain 38
chr9_+_126326809 0.15 ENST00000361171.8
ENST00000489637.3
multivesicular body subunit 12B
chr18_+_58864866 0.14 ENST00000588456.5
ENST00000591808.6
ENST00000589481.1
ENST00000591049.1
zinc finger protein 532
chr4_-_138242325 0.14 ENST00000280612.9
solute carrier family 7 member 11
chr16_-_3256587 0.14 ENST00000536379.5
ENST00000541159.5
ENST00000339854.8
ENST00000219596.6
MEFV innate immuity regulator, pyrin
chr19_+_35282520 0.14 ENST00000222304.5
hepcidin antimicrobial peptide
chr19_-_55179390 0.14 ENST00000590851.5
synaptotagmin 5
chr2_+_48568981 0.13 ENST00000394754.5
STON1-GTF2A1L readthrough
chr6_+_39792298 0.13 ENST00000633794.1
ENST00000274867.9
dishevelled associated activator of morphogenesis 2
chrY_+_14522573 0.13 ENST00000643089.1
ENST00000382872.5
neuroligin 4 Y-linked
chrX_+_41447322 0.13 ENST00000378220.2
ENST00000342595.2
nyctalopin
chr10_+_62049211 0.13 ENST00000309334.5
AT-rich interaction domain 5B
chr6_-_43308797 0.13 ENST00000274990.4
ENST00000372569.8
cysteine rich protein 3
chr15_+_92904447 0.12 ENST00000626782.2
chromodomain helicase DNA binding protein 2
chr22_-_31292445 0.12 ENST00000402249.7
ENST00000215912.10
ENST00000443175.1
ENST00000441972.5
phosphoinositide-3-kinase interacting protein 1
chr10_-_73252601 0.12 ENST00000372945.8
ENST00000372940.3
mitochondrial ribosomal protein S16
chrX_+_57592011 0.12 ENST00000374888.3
zinc finger X-linked duplicated B
chr8_+_10672646 0.12 ENST00000521818.1
chromosome 8 open reading frame 74
chr19_+_51127030 0.12 ENST00000599948.1
sialic acid binding Ig like lectin 9
chr8_+_406808 0.12 ENST00000352684.2
F-box protein 25

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.5 1.5 GO:0015917 aminophospholipid transport(GO:0015917)
0.3 1.3 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.3 0.8 GO:1903925 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.2 1.0 GO:0072674 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.2 0.6 GO:0002339 positive regulation of type I hypersensitivity(GO:0001812) B cell selection(GO:0002339) B cell cytokine production(GO:0002368)
0.2 0.5 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.2 1.0 GO:0051621 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.1 0.5 GO:0046462 monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.1 0.3 GO:0036071 N-glycan fucosylation(GO:0036071)
0.1 0.3 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.1 1.2 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.1 0.8 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.1 0.7 GO:0003138 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.1 0.3 GO:0090675 intermicrovillar adhesion(GO:0090675)
0.1 1.0 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.1 0.4 GO:0032185 septin cytoskeleton organization(GO:0032185)
0.1 0.2 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.1 0.3 GO:0034445 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.1 0.2 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.1 1.1 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.1 0.7 GO:0070836 caveola assembly(GO:0070836)
0.1 0.2 GO:0060957 endocardial cell fate commitment(GO:0060957) endocardial cushion cell fate commitment(GO:0061445)
0.1 2.6 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 0.3 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.1 0.8 GO:0072553 terminal button organization(GO:0072553)
0.1 0.3 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.1 0.6 GO:0070294 renal sodium ion absorption(GO:0070294)
0.1 0.2 GO:0018032 protein amidation(GO:0018032)
0.1 0.3 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.1 0.9 GO:0030043 actin filament fragmentation(GO:0030043)
0.1 0.2 GO:0031064 negative regulation of histone deacetylation(GO:0031064)
0.0 0.2 GO:0098957 anterograde axonal transport of mitochondrion(GO:0098957)
0.0 1.1 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.2 GO:1904117 response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117)
0.0 0.2 GO:0046601 positive regulation of centriole replication(GO:0046601)
0.0 0.7 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.2 GO:1990637 hepatic immune response(GO:0002384) response to prolactin(GO:1990637)
0.0 0.2 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.0 1.6 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.3 GO:0015705 iodide transport(GO:0015705)
0.0 0.5 GO:0071073 surfactant homeostasis(GO:0043129) positive regulation of phospholipid biosynthetic process(GO:0071073)
0.0 0.5 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.1 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.0 0.2 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.0 0.2 GO:0061083 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.0 0.4 GO:0030091 protein repair(GO:0030091)
0.0 0.3 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0 0.2 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.0 0.1 GO:1904562 phosphatidylinositol 5-phosphate metabolic process(GO:1904562)
0.0 0.1 GO:0060448 dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.0 0.2 GO:0002317 plasma cell differentiation(GO:0002317)
0.0 0.1 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0 0.1 GO:0019075 virus maturation(GO:0019075)
0.0 0.2 GO:0022614 membrane to membrane docking(GO:0022614)
0.0 0.1 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.0 0.6 GO:0006527 arginine catabolic process(GO:0006527)
0.0 0.7 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.0 0.2 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.0 0.3 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.4 GO:0045023 G0 to G1 transition(GO:0045023)
0.0 0.1 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.0 0.2 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.0 0.4 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 0.3 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.4 GO:0042074 cell migration involved in gastrulation(GO:0042074)
0.0 0.2 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.0 0.2 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.1 GO:1903595 positive regulation of histamine secretion by mast cell(GO:1903595)
0.0 0.9 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.1 GO:0060133 somatotropin secreting cell development(GO:0060133)
0.0 0.1 GO:0048058 compound eye corneal lens development(GO:0048058)
0.0 0.2 GO:0051414 response to cortisol(GO:0051414)
0.0 0.3 GO:0034465 response to carbon monoxide(GO:0034465)
0.0 0.1 GO:0009732 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0 0.1 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.0 0.2 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.1 GO:0019072 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.0 0.2 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.2 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.5 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 0.3 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.2 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.0 0.7 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.6 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 0.3 GO:0002003 angiotensin maturation(GO:0002003)
0.0 0.3 GO:0072520 seminiferous tubule development(GO:0072520)
0.0 0.1 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 0.2 GO:0001865 NK T cell differentiation(GO:0001865)
0.0 0.2 GO:2000394 positive regulation of lamellipodium morphogenesis(GO:2000394)
0.0 0.8 GO:0030195 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.0 0.1 GO:0050747 sphingomyelin biosynthetic process(GO:0006686) positive regulation of lipoprotein metabolic process(GO:0050747)
0.0 0.2 GO:0030903 notochord development(GO:0030903)
0.0 0.2 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.1 GO:1990822 basic amino acid transmembrane transport(GO:1990822)
0.0 0.6 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.2 GO:0006020 inositol metabolic process(GO:0006020)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.6 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.2 0.8 GO:0005595 collagen type XII trimer(GO:0005595)
0.1 1.7 GO:0000124 SAGA complex(GO:0000124)
0.1 0.7 GO:0031417 NatC complex(GO:0031417)
0.1 0.3 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.1 0.2 GO:0044753 amphisome(GO:0044753)
0.1 0.4 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.1 0.3 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.1 2.3 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 0.2 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.1 0.6 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.4 GO:0071953 elastic fiber(GO:0071953)
0.0 0.3 GO:0044214 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.0 0.2 GO:0048179 activin receptor complex(GO:0048179)
0.0 1.3 GO:0071564 npBAF complex(GO:0071564)
0.0 1.2 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 1.5 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.2 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.8 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.3 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.1 GO:1990769 proximal neuron projection(GO:1990769)
0.0 0.2 GO:0098536 deuterosome(GO:0098536)
0.0 0.2 GO:0043196 varicosity(GO:0043196)
0.0 0.2 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.2 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 0.3 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 1.3 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.1 GO:0070435 Shc-EGFR complex(GO:0070435)
0.0 0.2 GO:0032010 phagolysosome(GO:0032010)
0.0 0.1 GO:0000811 GINS complex(GO:0000811)
0.0 0.3 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.1 GO:0031084 BLOC-2 complex(GO:0031084)
0.0 0.6 GO:0042629 mast cell granule(GO:0042629)
0.0 0.2 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.2 GO:0070578 RISC-loading complex(GO:0070578)
0.0 1.6 GO:0005901 caveola(GO:0005901)
0.0 0.5 GO:0030125 clathrin vesicle coat(GO:0030125)
0.0 0.2 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.2 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.6 GO:0030348 syntaxin-3 binding(GO:0030348)
0.4 1.5 GO:0030226 apolipoprotein receptor activity(GO:0030226)
0.3 1.2 GO:0004948 calcitonin receptor activity(GO:0004948)
0.2 1.1 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.2 1.0 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.1 1.3 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 0.3 GO:0008424 glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
0.1 0.6 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.1 0.4 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.1 2.4 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.6 GO:0016403 dimethylargininase activity(GO:0016403)
0.1 0.8 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.1 0.8 GO:0097100 supercoiled DNA binding(GO:0097100)
0.1 0.5 GO:0001849 complement component C1q binding(GO:0001849)
0.1 0.5 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 0.2 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.1 0.2 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.1 0.2 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 0.2 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923)
0.1 0.2 GO:0035033 histone deacetylase regulator activity(GO:0035033) corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.0 1.0 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.2 GO:0070051 fibrinogen binding(GO:0070051)
0.0 0.3 GO:0102345 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.0 0.7 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.2 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.1 GO:0004608 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.0 0.2 GO:0032564 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.0 0.3 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.0 0.1 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 1.2 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.1 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0 1.2 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.3 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 0.2 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.5 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.3 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.2 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.0 0.3 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.2 GO:0070883 pre-miRNA binding(GO:0070883)
0.0 0.2 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.2 GO:0004568 chitinase activity(GO:0004568)
0.0 0.2 GO:0048039 ubiquinone binding(GO:0048039)
0.0 0.3 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.1 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 0.3 GO:0043422 protein kinase B binding(GO:0043422)
0.0 1.1 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.2 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.4 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 1.1 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.2 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.1 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.0 0.1 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.1 GO:0004396 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.0 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.1 GO:0048408 epidermal growth factor binding(GO:0048408)
0.0 0.4 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.7 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.2 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.2 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 1.6 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.2 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 1.0 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.6 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 1.7 SIG CHEMOTAXIS Genes related to chemotaxis
0.0 0.7 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.8 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 1.3 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 1.2 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.8 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.2 ST STAT3 PATHWAY STAT3 Pathway
0.0 0.3 PID REELIN PATHWAY Reelin signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.6 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1 0.8 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1 1.5 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 0.7 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.8 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 2.2 REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING Genes involved in Integrin alphaIIb beta3 signaling
0.0 1.5 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 1.0 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 1.1 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 1.7 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.2 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.2 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.0 0.2 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.3 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.1 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome