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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for POU2F2_POU3F1

Z-value: 0.68

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Transcription factors associated with POU2F2_POU3F1

Gene Symbol Gene ID Gene Info
ENSG00000028277.21 POU2F2
ENSG00000185668.8 POU3F1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
POU2F2hg38_v1_chr19_-_42132465_421324800.563.5e-03Click!
POU3F1hg38_v1_chr1_-_38046785_380468020.232.7e-01Click!

Activity profile of POU2F2_POU3F1 motif

Sorted Z-values of POU2F2_POU3F1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of POU2F2_POU3F1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr15_+_67166019 1.89 ENST00000537194.6
SMAD family member 3
chr6_+_37170133 1.89 ENST00000373509.6
Pim-1 proto-oncogene, serine/threonine kinase
chr6_-_142945028 1.32 ENST00000012134.7
HIVEP zinc finger 2
chr6_-_142945160 1.31 ENST00000367603.8
HIVEP zinc finger 2
chr6_-_10415043 1.31 ENST00000379613.10
transcription factor AP-2 alpha
chr6_+_31620701 1.22 ENST00000376033.3
ENST00000376007.8
proline rich coiled-coil 2A
chr7_+_18496162 1.15 ENST00000406072.5
histone deacetylase 9
chr2_+_151357583 1.07 ENST00000243347.5
TNF alpha induced protein 6
chr6_-_81752671 1.00 ENST00000320172.11
ENST00000369754.7
ENST00000369756.3
terminal nucleotidyltransferase 5A
chr14_+_64540734 0.97 ENST00000247207.7
heat shock protein family A (Hsp70) member 2
chr2_-_224947030 0.96 ENST00000409592.7
dedicator of cytokinesis 10
chr2_+_102355750 0.86 ENST00000233957.7
interleukin 18 receptor 1
chr1_-_149842736 0.84 ENST00000369159.2
H2A clustered histone 18
chr1_+_149851053 0.83 ENST00000607355.2
H2A clustered histone 19
chr17_+_20156045 0.79 ENST00000679801.1
ENST00000679740.1
ENST00000395522.6
ENST00000395525.7
sperm antigen with calponin homology and coiled-coil domains 1
chr14_-_106235582 0.78 ENST00000390607.2
immunoglobulin heavy variable 3-21
chr1_-_173050931 0.78 ENST00000404377.5
TNF superfamily member 18
chr1_+_67685170 0.78 ENST00000370985.4
ENST00000370986.9
ENST00000650283.1
ENST00000648742.1
growth arrest and DNA damage inducible alpha
chr14_-_106154113 0.76 ENST00000390603.2
immunoglobulin heavy variable 3-15
chr1_-_7940825 0.75 ENST00000377507.8
TNF receptor superfamily member 9
chr20_+_34704336 0.71 ENST00000374809.6
ENST00000374810.8
ENST00000451665.5
tumor protein p53 inducible nuclear protein 2
chr19_-_43619591 0.70 ENST00000598676.1
ENST00000300811.8
zinc finger protein 428
chr1_+_167329044 0.70 ENST00000367862.9
POU class 2 homeobox 1
chr11_-_62601818 0.68 ENST00000278823.7
metastasis associated 1 family member 2
chr17_-_7929793 0.63 ENST00000303790.3
potassium voltage-gated channel subfamily A regulatory beta subunit 3
chr10_+_24239181 0.60 ENST00000438429.5
KIAA1217
chr7_+_143222037 0.60 ENST00000408947.4
taste 2 receptor member 40
chr17_+_20155989 0.59 ENST00000395530.6
ENST00000581399.6
ENST00000679819.1
sperm antigen with calponin homology and coiled-coil domains 1
chr20_-_62407274 0.58 ENST00000279101.9
Cdk5 and Abl enzyme substrate 2
chr1_+_67685342 0.58 ENST00000617962.2
growth arrest and DNA damage inducible alpha
chr16_+_33827140 0.57 ENST00000562905.2
immunoglobulin heavy variable 3/OR16-13 (non-functional)
chr2_-_89297785 0.57 ENST00000465170.1
immunoglobulin kappa variable 1-37 (non-functional)
chr18_+_80109236 0.55 ENST00000262198.9
ENST00000560752.5
ADNP homeobox 2
chr11_-_133845495 0.54 ENST00000299140.8
ENST00000532889.1
spermatogenesis associated 19
chr14_-_106557465 0.54 ENST00000390625.3
immunoglobulin heavy variable 3-49
chr12_+_112906777 0.54 ENST00000452357.7
ENST00000445409.7
2'-5'-oligoadenylate synthetase 1
chr6_+_27147094 0.54 ENST00000377459.3
H2A clustered histone 12
chr12_+_112906949 0.53 ENST00000679971.1
ENST00000675868.2
ENST00000550883.2
ENST00000553152.2
ENST00000202917.10
ENST00000679467.1
ENST00000680659.1
ENST00000540589.3
ENST00000552526.2
ENST00000681228.1
ENST00000680934.1
ENST00000681700.1
ENST00000679987.1
2'-5'-oligoadenylate synthetase 1
chr2_+_89884740 0.53 ENST00000509129.1
immunoglobulin kappa variable 1D-37 (non-functional)
chr15_-_55249029 0.53 ENST00000566877.5
RAB27A, member RAS oncogene family
chr19_+_39412650 0.52 ENST00000425673.6
pleckstrin homology and RhoGEF domain containing G2
chr8_-_133102874 0.52 ENST00000395352.7
Src like adaptor
chr17_+_40015428 0.52 ENST00000394149.8
ENST00000225474.6
ENST00000331769.6
ENST00000394148.7
ENST00000577675.1
colony stimulating factor 3
chr12_+_112907006 0.52 ENST00000680455.1
ENST00000551241.6
ENST00000550689.2
ENST00000679841.1
ENST00000679494.1
ENST00000553185.2
2'-5'-oligoadenylate synthetase 1
chr6_+_29100609 0.51 ENST00000377171.3
olfactory receptor family 2 subfamily J member 1
chr6_-_10414985 0.51 ENST00000466073.5
ENST00000498450.3
transcription factor AP-2 alpha
chr6_-_26123910 0.51 ENST00000314332.5
ENST00000396984.1
H2B clustered histone 4
chr3_-_71583713 0.50 ENST00000649528.3
ENST00000471386.3
ENST00000493089.7
forkhead box P1
chr7_+_18495723 0.49 ENST00000681950.1
ENST00000622668.4
ENST00000405010.7
ENST00000406451.8
ENST00000441542.7
ENST00000428307.6
ENST00000681273.1
histone deacetylase 9
chr2_-_206218024 0.48 ENST00000407325.6
ENST00000612892.4
ENST00000411719.1
G protein-coupled receptor 1
chr2_+_89913982 0.48 ENST00000390265.2
immunoglobulin kappa variable 1D-33
chr1_-_2526585 0.47 ENST00000378466.9
ENST00000435556.8
pantothenate kinase 4 (inactive)
chr6_-_33711717 0.46 ENST00000374214.3
ubiquinol-cytochrome c reductase complex assembly factor 2
chr6_-_138499487 0.44 ENST00000343505.9
NHS like 1
chr2_+_219279330 0.42 ENST00000425450.5
ENST00000392086.8
ENST00000421532.5
ENST00000336576.10
DnaJ heat shock protein family (Hsp40) member B2
chr6_-_27132750 0.42 ENST00000607124.1
ENST00000339812.3
H2B clustered histone 11
chr2_+_85429448 0.41 ENST00000651736.1
SH2 domain containing 6
chr2_-_89268506 0.40 ENST00000473726.1
immunoglobulin kappa variable 1-33
chr6_+_26251607 0.40 ENST00000619466.2
H2B clustered histone 9
chr3_-_71130557 0.40 ENST00000497355.7
forkhead box P1
chr3_-_108058361 0.40 ENST00000398258.7
CD47 molecule
chr11_-_3642273 0.39 ENST00000359918.8
ADP-ribosyltransferase 5
chr19_-_45584810 0.39 ENST00000323060.3
outer mitochondrial membrane lipid metabolism regulator OPA3
chr6_+_10585748 0.39 ENST00000265012.5
glucosaminyl (N-acetyl) transferase 2 (I blood group)
chr11_+_69641146 0.38 ENST00000227507.3
ENST00000536559.1
cyclin D1
chr19_+_11355386 0.38 ENST00000251473.9
ENST00000591329.5
ENST00000586380.5
phospholipid phosphatase related 2
chr16_+_33009175 0.37 ENST00000565407.2
immunoglobulin heavy variable 3/OR16-8 (non-functional)
chr6_+_27893411 0.37 ENST00000616182.2
H2B clustered histone 17
chr7_-_100586119 0.37 ENST00000310300.11
leucine rich repeats and calponin homology domain containing 4
chr1_+_149886906 0.37 ENST00000331380.4
H2A clustered histone 20
chr3_-_71130892 0.36 ENST00000491238.7
ENST00000674446.1
forkhead box P1
chr6_-_27893175 0.36 ENST00000359611.4
H2A clustered histone 17
chr8_-_26045360 0.36 ENST00000520164.6
EBF transcription factor 2
chr19_+_11355491 0.36 ENST00000591608.1
phospholipid phosphatase related 2
chr19_-_1132208 0.36 ENST00000438103.6
strawberry notch homolog 2
chr6_-_53148822 0.36 ENST00000259803.8
glial cells missing transcription factor 1
chr3_-_123884290 0.36 ENST00000346322.9
ENST00000360772.7
ENST00000360304.8
myosin light chain kinase
chr6_-_33711684 0.36 ENST00000374231.8
ENST00000607484.6
ubiquinol-cytochrome c reductase complex assembly factor 2
chr3_-_71130963 0.36 ENST00000649695.2
forkhead box P1
chr6_-_26216673 0.35 ENST00000541790.3
H2B clustered histone 8
chr1_-_10964201 0.34 ENST00000418570.6
chromosome 1 open reading frame 127
chr2_+_90154073 0.34 ENST00000611391.1
immunoglobulin kappa variable 1D-13
chr19_-_17405554 0.34 ENST00000252593.7
bone marrow stromal cell antigen 2
chr9_+_89605004 0.34 ENST00000252506.11
ENST00000375769.1
growth arrest and DNA damage inducible gamma
chr14_+_103107516 0.34 ENST00000560304.1
exocyst complex component 3 like 4
chr19_-_14884761 0.34 ENST00000642123.1
olfactory receptor family 7 subfamily A member 17
chr2_+_54558348 0.34 ENST00000333896.5
spectrin beta, non-erythrocytic 1
chr16_+_56935371 0.31 ENST00000568358.1
homocysteine inducible ER protein with ubiquitin like domain 1
chr2_+_173354820 0.31 ENST00000347703.7
ENST00000410101.7
ENST00000410019.3
ENST00000306721.8
cell division cycle associated 7
chr2_-_171894227 0.31 ENST00000422440.7
solute carrier family 25 member 12
chr19_-_893172 0.31 ENST00000325464.6
ENST00000312090.10
mediator complex subunit 16
chr1_+_59310071 0.31 ENST00000371212.5
FGGY carbohydrate kinase domain containing
chr16_-_33845229 0.30 ENST00000569103.2
immunoglobulin heavy variable 3/OR16-17 (non-functional)
chr14_-_106211453 0.30 ENST00000390606.3
immunoglobulin heavy variable 3-20
chr22_+_22811737 0.30 ENST00000390315.3
immunoglobulin lambda variable 3-10
chr19_-_893200 0.29 ENST00000269814.8
ENST00000395808.7
mediator complex subunit 16
chr21_-_30829755 0.29 ENST00000621162.1
keratin associated protein 7-1
chr17_+_3207539 0.29 ENST00000641322.1
ENST00000641732.2
olfactory receptor family 1 subfamily A member 1
chr14_-_106791226 0.29 ENST00000433072.2
immunoglobulin heavy variable 3-72
chr1_-_183653307 0.28 ENST00000308641.6
apolipoprotein B mRNA editing enzyme catalytic polypeptide like 4
chr22_+_22030934 0.28 ENST00000390282.2
immunoglobulin lambda variable 4-69
chr19_-_18397596 0.27 ENST00000595840.1
ENST00000339007.4
leucine rich repeat containing 25
chr8_-_33513077 0.27 ENST00000360742.9
ENST00000523305.1
ENST00000431156.7
ENST00000613904.1
TELO2 interacting protein 2
chr5_-_67196791 0.27 ENST00000256447.5
CD180 molecule
chr8_-_133102477 0.26 ENST00000522119.5
ENST00000523610.5
ENST00000338087.10
ENST00000521302.5
ENST00000519558.5
ENST00000519747.5
ENST00000517648.5
Src like adaptor
chr1_-_201115372 0.26 ENST00000458416.2
achaete-scute family bHLH transcription factor 5
chr17_-_37745018 0.26 ENST00000613727.4
ENST00000614313.4
ENST00000617811.5
ENST00000621123.4
HNF1 homeobox B
chr6_+_155216637 0.26 ENST00000275246.11
TIAM Rac1 associated GEF 2
chr17_-_75131729 0.26 ENST00000245552.7
ENST00000582170.1
5', 3'-nucleotidase, cytosolic
chr17_+_7650916 0.26 ENST00000250111.9
ATPase Na+/K+ transporting subunit beta 2
chr5_+_126423122 0.26 ENST00000515200.5
GRAM domain containing 2B
chr15_-_58065703 0.25 ENST00000249750.9
aldehyde dehydrogenase 1 family member A2
chr14_-_24146314 0.25 ENST00000559056.5
proteasome activator subunit 2
chr7_+_128672275 0.25 ENST00000684498.1
ENST00000641605.1
ENST00000682356.1
ENST00000477515.3
family with sequence similarity 71 member F2
chr8_-_25458389 0.25 ENST00000221200.9
potassium channel tetramerization domain containing 9
chr20_+_836052 0.25 ENST00000246100.3
family with sequence similarity 110 member A
chr5_+_126423176 0.25 ENST00000542322.5
ENST00000544396.5
GRAM domain containing 2B
chr14_-_106130061 0.25 ENST00000390602.3
immunoglobulin heavy variable 3-13
chr18_-_77127935 0.25 ENST00000581878.5
myelin basic protein
chr5_-_159099909 0.25 ENST00000313708.11
EBF transcription factor 1
chr5_+_76819022 0.25 ENST00000296677.5
F2R like trypsin receptor 1
chr5_+_126423363 0.25 ENST00000285689.8
GRAM domain containing 2B
chr19_+_42284020 0.25 ENST00000160740.7
capicua transcriptional repressor
chr4_-_47981535 0.25 ENST00000402813.9
cyclic nucleotide gated channel subunit alpha 1
chr21_-_34526850 0.25 ENST00000481448.5
ENST00000381132.6
regulator of calcineurin 1
chrX_+_38801451 0.25 ENST00000378474.3
ENST00000336949.7
MID1 interacting protein 1
chr15_-_58065734 0.24 ENST00000347587.7
aldehyde dehydrogenase 1 family member A2
chr10_+_96000091 0.24 ENST00000424464.5
ENST00000410012.6
ENST00000344386.3
coiled-coil and C2 domain containing 2B
chr5_+_80960694 0.24 ENST00000638442.1
Ras protein specific guanine nucleotide releasing factor 2
chr1_+_166839425 0.24 ENST00000449930.5
ENST00000367876.9
pogo transposable element derived with KRAB domain
chr19_+_19033575 0.24 ENST00000392335.6
ENST00000537263.5
ENST00000540707.5
ENST00000535612.6
ENST00000541725.5
ENST00000269932.10
ENST00000546344.5
ENST00000540792.5
ENST00000536098.5
ENST00000541898.5
armadillo repeat containing 6
chr12_-_10998304 0.23 ENST00000538986.2
taste 2 receptor member 20
chr10_+_104353820 0.23 ENST00000369704.8
cilia and flagella associated protein 58
chr12_-_16606795 0.23 ENST00000447609.5
LIM domain only 3
chr11_+_64318091 0.23 ENST00000265462.9
ENST00000352435.8
ENST00000347941.4
peroxiredoxin 5
chr19_-_19170248 0.23 ENST00000410050.5
ENST00000424583.7
ENST00000409224.5
ENST00000409447.2
myocyte enhancer factor 2B
chr11_+_27055215 0.23 ENST00000525090.1
gamma-butyrobetaine hydroxylase 1
chr12_-_7092422 0.23 ENST00000543835.5
ENST00000647956.2
ENST00000535233.6
complement C1r
chr19_-_45584769 0.22 ENST00000263275.5
outer mitochondrial membrane lipid metabolism regulator OPA3
chr17_-_48817217 0.22 ENST00000393382.8
tubulin tyrosine ligase like 6
chrX_+_38801417 0.22 ENST00000614558.2
ENST00000457894.5
MID1 interacting protein 1
chr3_+_63443306 0.22 ENST00000472899.5
ENST00000479198.5
ENST00000460711.5
ENST00000465156.1
synaptoporin
chr18_-_63644250 0.22 ENST00000341074.10
ENST00000436264.1
serpin family B member 4
chr5_-_36301883 0.22 ENST00000502994.5
ENST00000515759.5
ENST00000296604.8
RAN binding protein 3 like
chr19_+_40799155 0.22 ENST00000303961.9
egl-9 family hypoxia inducible factor 2
chr4_-_109302643 0.21 ENST00000399126.1
ENST00000505591.1
ENST00000399132.6
collagen type XXV alpha 1 chain
chr20_+_56629296 0.21 ENST00000201031.3
transcription factor AP-2 gamma
chr15_-_58065870 0.21 ENST00000537372.5
aldehyde dehydrogenase 1 family member A2
chr3_+_63443076 0.21 ENST00000295894.9
synaptoporin
chr6_+_29301701 0.21 ENST00000641895.1
olfactory receptor family 14 subfamily J member 1
chr2_+_90172802 0.20 ENST00000390277.3
immunoglobulin kappa variable 3D-11
chr19_+_35358460 0.20 ENST00000327809.5
free fatty acid receptor 3
chr15_+_80441229 0.20 ENST00000533983.5
ENST00000527771.5
ENST00000525103.1
aryl hydrocarbon receptor nuclear translocator 2
chr21_-_34888683 0.20 ENST00000344691.8
ENST00000358356.9
RUNX family transcription factor 1
chr10_+_122163426 0.20 ENST00000360561.7
transforming acidic coiled-coil containing protein 2
chr3_-_71583683 0.20 ENST00000649631.1
ENST00000648718.1
forkhead box P1
chr17_-_3063607 0.20 ENST00000575751.1
olfactory receptor family 1 subfamily D member 5
chr1_-_196608359 0.19 ENST00000609185.5
ENST00000451324.6
ENST00000367433.9
ENST00000294725.14
potassium sodium-activated channel subfamily T member 2
chr10_+_122163590 0.19 ENST00000368999.5
transforming acidic coiled-coil containing protein 2
chr2_+_113406368 0.19 ENST00000453673.3
immunoglobulin kappa variable 1/OR2-108 (non-functional)
chr10_+_122163672 0.19 ENST00000369004.7
ENST00000260733.7
transforming acidic coiled-coil containing protein 2
chr19_-_46788586 0.19 ENST00000542575.6
solute carrier family 1 member 5
chr11_+_27041313 0.19 ENST00000528583.5
gamma-butyrobetaine hydroxylase 1
chr6_+_26183750 0.19 ENST00000614097.3
H2B clustered histone 6
chr3_-_71583592 0.19 ENST00000650156.1
ENST00000649596.1
forkhead box P1
chr2_-_89117844 0.19 ENST00000490686.1
immunoglobulin kappa variable 1-17
chr2_-_88966767 0.19 ENST00000464162.1
immunoglobulin kappa variable 1-6
chr15_-_66356672 0.19 ENST00000261881.9
TIMELESS interacting protein
chr7_+_123601815 0.19 ENST00000451215.6
ankyrin repeat and SOCS box containing 15
chr1_-_165445088 0.19 ENST00000359842.10
retinoid X receptor gamma
chr12_+_107318395 0.18 ENST00000420571.6
ENST00000280758.10
BTB domain containing 11
chr1_+_156150008 0.18 ENST00000355014.6
semaphorin 4A
chr6_-_127900958 0.18 ENST00000434358.3
ENST00000630369.2
ENST00000368248.4
thymocyte selection associated
chr17_-_75131683 0.18 ENST00000578407.5
5', 3'-nucleotidase, cytosolic
chr1_+_207496268 0.18 ENST00000529814.1
complement C3b/C4b receptor 1 (Knops blood group)
chr1_+_27773189 0.18 ENST00000373943.9
ENST00000440806.2
syntaxin 12
chr10_+_110005804 0.18 ENST00000360162.7
adducin 3
chr11_-_18236795 0.18 ENST00000278222.7
serum amyloid A4, constitutive
chr1_+_32200587 0.18 ENST00000373602.10
ENST00000421922.6
ENST00000681230.1
coiled-coil domain containing 28B
chr7_+_123601836 0.18 ENST00000434204.5
ankyrin repeat and SOCS box containing 15
chr7_-_113087720 0.18 ENST00000297146.7
G protein-coupled receptor 85
chr2_-_157325808 0.18 ENST00000410096.6
ENST00000420719.6
ENST00000409216.5
ENST00000419116.2
ermin
chr6_-_43687774 0.18 ENST00000372133.8
ENST00000372116.5
ENST00000427312.1
mitochondrial ribosomal protein S18A
chr6_+_41042462 0.17 ENST00000373161.6
translocator protein 2
chr11_-_34357994 0.17 ENST00000435224.3
ankyrin repeat and BTB domain containing 2
chr2_-_89100352 0.17 ENST00000479981.1
immunoglobulin kappa variable 1-16
chr17_-_10804092 0.17 ENST00000581851.1
transmembrane protein 238 like
chr14_-_50830479 0.17 ENST00000382043.8
ninein
chr11_+_27040725 0.17 ENST00000529202.5
ENST00000263182.8
gamma-butyrobetaine hydroxylase 1
chr15_-_55917080 0.17 ENST00000506154.1
NEDD4 E3 ubiquitin protein ligase
chr11_-_6030758 0.16 ENST00000641900.1
olfactory receptor family 56 subfamily A member 1
chr10_-_62236112 0.16 ENST00000315289.6
rhotekin 2
chr2_+_90234809 0.16 ENST00000443397.5
immunoglobulin kappa variable 3D-7
chr22_-_23754376 0.16 ENST00000398465.3
ENST00000248948.4
V-set pre-B cell surrogate light chain 3
chr22_+_22734577 0.16 ENST00000390310.3
immunoglobulin lambda variable 2-18
chr12_-_10909562 0.15 ENST00000390677.2
taste 2 receptor member 13
chr2_+_200308943 0.15 ENST00000619961.4
spermatogenesis associated serine rich 2 like
chr16_-_8975320 0.15 ENST00000673704.1
ubiquitin specific peptidase 7
chr19_-_3971051 0.15 ENST00000545797.7
ENST00000596311.5
death associated protein kinase 3
chr3_+_119597874 0.15 ENST00000488919.5
ENST00000273371.9
ENST00000495992.5
phospholipase A1 member A

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.8 GO:0003409 optic cup structural organization(GO:0003409)
0.3 1.9 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.2 0.8 GO:2000329 negative regulation of T-helper 17 cell lineage commitment(GO:2000329)
0.2 1.9 GO:0070561 vitamin D receptor signaling pathway(GO:0070561)
0.1 0.4 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.1 2.0 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.1 1.6 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1 0.3 GO:0045957 regulation of complement activation, alternative pathway(GO:0030451) negative regulation of complement activation, alternative pathway(GO:0045957)
0.1 0.3 GO:1901253 negative regulation of intracellular transport of viral material(GO:1901253)
0.1 0.7 GO:2001180 negative regulation of interleukin-10 secretion(GO:2001180)
0.1 0.9 GO:0035655 interleukin-18-mediated signaling pathway(GO:0035655)
0.1 0.3 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.1 0.3 GO:0044007 negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage(GO:0010768) transmission of virus(GO:0019089) dissemination or transmission of symbiont from host(GO:0044007) dissemination or transmission of organism from other organism involved in symbiotic interaction(GO:0051821)
0.1 0.4 GO:0060018 astrocyte fate commitment(GO:0060018)
0.1 0.3 GO:0090222 centrosome-templated microtubule nucleation(GO:0090222)
0.1 0.3 GO:0035565 regulation of pronephros size(GO:0035565)
0.1 0.5 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.1 0.3 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.1 0.7 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.1 0.8 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551)
0.1 0.3 GO:0002879 positive regulation of acute inflammatory response to non-antigenic stimulus(GO:0002879)
0.1 0.2 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.1 0.5 GO:0035926 chemokine (C-C motif) ligand 2 secretion(GO:0035926)
0.1 0.2 GO:1990009 cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473) retinal cell apoptotic process(GO:1990009)
0.1 1.5 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.1 0.3 GO:1903288 positive regulation of potassium ion import(GO:1903288)
0.1 0.4 GO:0071105 response to interleukin-11(GO:0071105)
0.1 1.0 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 0.4 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.1 0.6 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.1 0.4 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.4 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.2 GO:0036229 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.0 0.1 GO:0003363 lamellipodium assembly involved in ameboidal cell migration(GO:0003363)
0.0 0.2 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0 0.3 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.0 0.4 GO:0097475 motor neuron migration(GO:0097475)
0.0 1.0 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.5 GO:0030223 neutrophil differentiation(GO:0030223)
0.0 0.1 GO:1900222 positive regulation of transcription via serum response element binding(GO:0010735) negative regulation of beta-amyloid clearance(GO:1900222)
0.0 0.1 GO:0060031 mediolateral intercalation(GO:0060031) planar cell polarity pathway involved in gastrula mediolateral intercalation(GO:0060775)
0.0 0.3 GO:0060844 arterial endothelial cell fate commitment(GO:0060844) blood vessel endothelial cell fate commitment(GO:0060846) endothelial cell fate specification(GO:0060847) blood vessel endothelial cell fate specification(GO:0097101) positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 0.1 GO:0031296 B cell costimulation(GO:0031296)
0.0 0.1 GO:2000317 negative regulation of T-helper 17 type immune response(GO:2000317) negative regulation of T-helper 17 cell differentiation(GO:2000320)
0.0 2.4 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.2 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 0.1 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.0 0.4 GO:0070141 response to UV-A(GO:0070141)
0.0 0.2 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.1 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.0 0.1 GO:2000583 regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
0.0 0.1 GO:0060940 epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940)
0.0 0.8 GO:0030728 ovulation(GO:0030728)
0.0 0.2 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.1 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0 0.1 GO:0060157 urinary bladder development(GO:0060157)
0.0 0.1 GO:0042668 auditory receptor cell fate determination(GO:0042668)
0.0 0.2 GO:0051013 microtubule severing(GO:0051013)
0.0 0.3 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.5 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.0 GO:0030185 nitric oxide transport(GO:0030185)
0.0 0.3 GO:0051601 exocyst localization(GO:0051601)
0.0 0.2 GO:0048478 replication fork protection(GO:0048478)
0.0 0.2 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.0 0.5 GO:0006853 carnitine shuttle(GO:0006853)
0.0 0.1 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.0 0.1 GO:0072086 specification of loop of Henle identity(GO:0072086)
0.0 0.5 GO:0009223 pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.0 0.1 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.0 0.4 GO:0045199 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0 0.4 GO:0008228 opsonization(GO:0008228)
0.0 0.3 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.0 0.1 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.0 0.1 GO:0071676 negative regulation of mononuclear cell migration(GO:0071676)
0.0 0.4 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.0 0.1 GO:0001978 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) baroreceptor response to increased systemic arterial blood pressure(GO:0001983) positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.0 0.6 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.0 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.0 0.2 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 1.6 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.2 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.1 GO:0048733 sebaceous gland development(GO:0048733)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.7 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 0.1 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.0 0.1 GO:1902219 negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.0 0.1 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.0 GO:0000023 maltose metabolic process(GO:0000023)
0.0 0.1 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.0 0.0 GO:0036135 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.0 0.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.7 GO:0010762 regulation of fibroblast migration(GO:0010762)
0.0 0.0 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.0 0.1 GO:0070166 enamel mineralization(GO:0070166)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.9 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 1.0 GO:0072687 CatSper complex(GO:0036128) meiotic spindle(GO:0072687)
0.1 0.3 GO:0008537 proteasome activator complex(GO:0008537)
0.1 2.5 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.3 GO:0032437 cuticular plate(GO:0032437)
0.0 0.4 GO:0033269 internode region of axon(GO:0033269)
0.0 0.3 GO:1990037 Lewy body core(GO:1990037)
0.0 0.5 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.3 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.2 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.0 0.3 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.1 GO:0031673 H zone(GO:0031673)
0.0 2.4 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.1 GO:1990031 pinceau fiber(GO:1990031)
0.0 0.4 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.3 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.8 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.1 GO:0044327 dendritic spine head(GO:0044327)
0.0 1.1 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.6 GO:0016592 mediator complex(GO:0016592)
0.0 0.3 GO:0000145 exocyst(GO:0000145)
0.0 0.1 GO:0005638 lamin filament(GO:0005638)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.9 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.3 0.9 GO:0042008 interleukin-18 receptor activity(GO:0042008)
0.2 0.6 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.1 0.6 GO:0010861 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.1 0.3 GO:0001861 complement component C4b receptor activity(GO:0001861) complement component C3b receptor activity(GO:0004877)
0.1 1.6 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 0.3 GO:0019150 D-ribulokinase activity(GO:0019150)
0.1 1.9 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.1 0.4 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.1 1.6 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 0.5 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 0.3 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.1 1.0 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.1 0.4 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1 0.3 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.1 0.2 GO:0052739 phosphatidylserine 1-acylhydrolase activity(GO:0052739)
0.0 2.5 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.7 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.4 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.4 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.5 GO:0019103 pyrimidine nucleotide binding(GO:0019103)
0.0 0.2 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.2 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.3 GO:0050816 phosphoserine binding(GO:0050815) phosphothreonine binding(GO:0050816)
0.0 0.1 GO:0008893 guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity(GO:0008893) diphosphoric monoester hydrolase activity(GO:0016794)
0.0 0.3 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.2 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.2 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 1.1 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.2 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.1 GO:0052854 (S)-2-hydroxy-acid oxidase activity(GO:0003973) very-long-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052852) long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity(GO:0052853) medium-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052854)
0.0 0.2 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.1 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.4 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.7 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.1 GO:0070878 primary miRNA binding(GO:0070878)
0.0 0.2 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.1 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 1.9 GO:0050681 androgen receptor binding(GO:0050681)
0.0 2.3 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.1 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.7 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.5 GO:0031489 myosin V binding(GO:0031489)
0.0 0.2 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.1 GO:0015235 cobalamin transporter activity(GO:0015235)
0.0 0.1 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.5 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.3 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.7 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.0 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.0 0.4 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.0 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.0 0.0 GO:0032450 maltose alpha-glucosidase activity(GO:0032450)
0.0 0.3 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.9 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 1.1 PID IL5 PATHWAY IL5-mediated signaling events
0.0 1.7 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.4 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 1.8 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 1.2 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.9 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.6 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.5 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.5 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.7 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 1.1 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.5 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 1.7 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.2 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.4 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.3 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.3 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 1.0 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.2 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis