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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for POU3F3_POU3F4

Z-value: 0.99

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Transcription factors associated with POU3F3_POU3F4

Gene Symbol Gene ID Gene Info
ENSG00000198914.5 POU3F3
ENSG00000196767.9 POU3F4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
POU3F4hg38_v1_chrX_+_83508284_835083090.654.5e-04Click!
POU3F3hg38_v1_chr2_+_104853259_104853490-0.058.0e-01Click!

Activity profile of POU3F3_POU3F4 motif

Sorted Z-values of POU3F3_POU3F4 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of POU3F3_POU3F4

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr6_+_127577168 3.97 ENST00000329722.8
chromosome 6 open reading frame 58
chr1_-_169734064 3.87 ENST00000333360.12
selectin E
chr5_+_126423122 2.74 ENST00000515200.5
GRAM domain containing 2B
chr5_+_126423176 2.72 ENST00000542322.5
ENST00000544396.5
GRAM domain containing 2B
chr5_+_126423363 2.71 ENST00000285689.8
GRAM domain containing 2B
chr3_-_127736329 2.69 ENST00000398101.7
monoglyceride lipase
chr3_-_108058361 2.60 ENST00000398258.7
CD47 molecule
chr10_-_48604952 2.38 ENST00000417912.6
Rho GTPase activating protein 22
chr21_-_36542600 2.33 ENST00000399136.5
claudin 14
chr2_-_219399981 2.24 ENST00000519905.1
ENST00000523282.5
ENST00000434339.5
ENST00000457935.5
aspartyl aminopeptidase
chr11_-_57324907 2.14 ENST00000358252.8
tankyrase 1 binding protein 1
chr6_+_29100609 2.08 ENST00000377171.3
olfactory receptor family 2 subfamily J member 1
chr10_-_48605032 1.90 ENST00000249601.9
Rho GTPase activating protein 22
chr7_+_120273129 1.77 ENST00000331113.9
potassium voltage-gated channel subfamily D member 2
chr22_+_30080460 1.62 ENST00000336726.11
HORMA domain containing 2
chr19_-_48513161 1.62 ENST00000673139.1
lemur tyrosine kinase 3
chr2_-_24328113 1.59 ENST00000622089.4
intersectin 2
chr5_-_160852200 1.49 ENST00000327245.10
ATPase phospholipid transporting 10B (putative)
chr8_+_31639755 1.48 ENST00000520407.5
neuregulin 1
chr22_+_38705922 1.48 ENST00000216044.10
GTP binding protein 1
chr19_-_43670153 1.47 ENST00000601723.5
ENST00000339082.7
ENST00000340093.8
plasminogen activator, urokinase receptor
chr6_-_46491956 1.45 ENST00000306764.11
regulator of calcineurin 2
chr6_-_154430495 1.38 ENST00000424998.3
CNKSR family member 3
chr2_-_60553409 1.36 ENST00000358510.6
ENST00000643004.1
BAF chromatin remodeling complex subunit BCL11A
chr3_-_112846856 1.25 ENST00000488794.5
CD200 receptor 1 like
chr5_-_161546671 1.13 ENST00000517547.5
gamma-aminobutyric acid type A receptor subunit beta2
chr16_-_695946 1.13 ENST00000562563.1
F-box and leucine rich repeat protein 16
chr10_+_69801892 1.12 ENST00000398978.8
ENST00000645393.2
ENST00000354547.7
ENST00000674121.1
ENST00000673842.1
ENST00000520267.5
collagen type XIII alpha 1 chain
chr3_-_112845950 1.11 ENST00000398214.5
CD200 receptor 1 like
chr7_-_139777986 1.10 ENST00000406875.8
homeodomain interacting protein kinase 2
chr11_-_35420017 1.08 ENST00000643000.1
ENST00000646099.1
ENST00000647372.1
ENST00000642578.1
solute carrier family 1 member 2
chr5_-_161546970 1.08 ENST00000675303.1
gamma-aminobutyric acid type A receptor subunit beta2
chr15_+_70936487 1.04 ENST00000558456.5
ENST00000560158.6
ENST00000558808.5
ENST00000559806.5
ENST00000559069.1
leucine rich repeat containing 49
chr8_+_60678705 1.03 ENST00000423902.7
chromodomain helicase DNA binding protein 7
chr5_+_96876480 1.03 ENST00000437043.8
ENST00000379904.8
endoplasmic reticulum aminopeptidase 2
chr8_-_63026179 0.99 ENST00000677919.1
gamma-glutamyl hydrolase
chr3_-_58627596 0.98 ENST00000474531.5
ENST00000465970.1
family with sequence similarity 107 member A
chr4_-_121164314 0.96 ENST00000057513.8
TNFAIP3 interacting protein 3
chr11_-_102625332 0.95 ENST00000260228.3
matrix metallopeptidase 20
chr18_+_616672 0.95 ENST00000338387.11
clusterin like 1
chr6_+_36676455 0.94 ENST00000615513.4
cyclin dependent kinase inhibitor 1A
chr5_+_141382702 0.92 ENST00000617050.1
ENST00000518325.2
protocadherin gamma subfamily A, 7
chr22_-_30246739 0.92 ENST00000403987.3
ENST00000249075.4
LIF interleukin 6 family cytokine
chr1_+_53459391 0.91 ENST00000371445.3
DMRT like family B with proline rich C-terminal 1
chr3_+_112086364 0.91 ENST00000264848.10
chromosome 3 open reading frame 52
chr6_+_36676489 0.91 ENST00000448526.6
cyclin dependent kinase inhibitor 1A
chrX_+_47193796 0.90 ENST00000442035.5
ENST00000335972.11
ENST00000457753.5
ubiquitin like modifier activating enzyme 1
chr2_+_161136901 0.88 ENST00000259075.6
ENST00000432002.5
TRAF family member associated NFKB activator
chr4_-_25030922 0.87 ENST00000382114.9
leucine rich repeat LGI family member 2
chr3_+_112086335 0.85 ENST00000431717.6
ENST00000480282.5
chromosome 3 open reading frame 52
chr11_+_54706832 0.85 ENST00000319760.8
olfactory receptor family 4 subfamily A member 5
chr7_+_123601815 0.85 ENST00000451215.6
ankyrin repeat and SOCS box containing 15
chr2_-_174846405 0.84 ENST00000409597.5
ENST00000413882.6
chimerin 1
chr16_-_70801131 0.82 ENST00000261776.10
VAC14 component of PIKFYVE complex
chr1_+_167329044 0.79 ENST00000367862.9
POU class 2 homeobox 1
chrM_+_5824 0.75 ENST00000361624.2
mitochondrially encoded cytochrome c oxidase I
chr3_-_186109067 0.75 ENST00000306376.10
ETS variant transcription factor 5
chr11_-_26572130 0.75 ENST00000527569.1
mucin 15, cell surface associated
chr13_+_108629605 0.74 ENST00000457511.7
myosin XVI
chr8_+_66126896 0.74 ENST00000353317.9
tripartite motif containing 55
chr10_+_69801874 0.74 ENST00000357811.8
collagen type XIII alpha 1 chain
chr12_-_84892120 0.73 ENST00000680379.1
solute carrier family 6 member 15
chr5_-_161546708 0.70 ENST00000393959.6
gamma-aminobutyric acid type A receptor subunit beta2
chr1_+_248030070 0.70 ENST00000642011.1
ENST00000641771.1
olfactory receptor family 2 subfamily L member 2
chr11_-_35419899 0.69 ENST00000646847.1
ENST00000449068.2
ENST00000643401.1
ENST00000645966.1
ENST00000647104.1
solute carrier family 1 member 2
chr6_-_11778781 0.68 ENST00000414691.8
ENST00000229583.9
androgen dependent TFPI regulating protein
chr1_+_244352627 0.68 ENST00000366537.5
ENST00000308105.5
chromosome 1 open reading frame 100
chr5_+_141373878 0.65 ENST00000517434.3
ENST00000610583.1
protocadherin gamma subfamily A, 6
chr1_-_247758680 0.65 ENST00000408896.4
olfactory receptor family 1 subfamily C member 1
chr3_+_35680994 0.65 ENST00000441454.5
cAMP regulated phosphoprotein 21
chr18_+_616711 0.64 ENST00000579494.1
clusterin like 1
chr1_+_212432891 0.64 ENST00000366988.5
neudesin neurotrophic factor
chr4_-_167234579 0.64 ENST00000502330.5
ENST00000357154.7
ENST00000421836.6
SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3
chr12_+_18262730 0.63 ENST00000675017.1
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma
chr17_-_10549612 0.63 ENST00000532183.6
ENST00000397183.6
ENST00000420805.1
myosin heavy chain 2
chrX_+_1591590 0.62 ENST00000313871.9
ENST00000381261.8
A-kinase anchoring protein 17A
chrX_+_41688967 0.62 ENST00000378142.9
G protein-coupled receptor 34
chr8_-_118621901 0.61 ENST00000409003.5
ENST00000524796.6
ENST00000314727.9
sterile alpha motif domain containing 12
chr17_-_42388467 0.60 ENST00000678792.1
ENST00000679166.1
ENST00000677442.1
ENST00000677723.1
ENST00000678905.1
ENST00000677479.1
ENST00000678043.1
ENST00000677152.1
ENST00000677603.1
ENST00000588969.5
ENST00000678535.1
ENST00000679185.1
ENST00000677030.1
ENST00000679014.1
ENST00000678044.1
ENST00000678827.1
signal transducer and activator of transcription 3
chr4_-_167234552 0.59 ENST00000512648.5
SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3
chr12_-_42237727 0.59 ENST00000548917.1
YY1 associated factor 2
chr4_-_167234426 0.59 ENST00000541354.5
ENST00000509854.5
ENST00000512681.5
ENST00000357545.9
ENST00000510741.5
ENST00000510403.5
SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3
chr7_-_108240049 0.59 ENST00000379022.8
neuronal cell adhesion molecule
chr6_-_26108125 0.57 ENST00000338379.6
H1.6 linker histone, cluster member
chr9_-_34458533 0.57 ENST00000379089.5
ENST00000379087.5
ENST00000379084.5
ENST00000379081.5
ENST00000379080.5
ENST00000422409.5
ENST00000379078.1
ENST00000651358.1
ENST00000445726.5
ENST00000297620.8
family with sequence similarity 219 member A
chr20_+_49936371 0.57 ENST00000244061.6
ENST00000625177.3
ENST00000622920.1
ring finger protein 114
chr11_-_40293102 0.56 ENST00000527150.5
leucine rich repeat containing 4C
chr15_+_64387828 0.56 ENST00000261884.8
thyroid hormone receptor interactor 4
chr5_+_150601060 0.56 ENST00000394243.5
synaptopodin
chr7_-_14841267 0.56 ENST00000406247.7
ENST00000399322.7
diacylglycerol kinase beta
chr21_-_41926680 0.55 ENST00000329623.11
C2 calcium dependent domain containing 2
chr17_-_42388360 0.54 ENST00000678960.1
ENST00000404395.3
ENST00000389272.7
ENST00000677421.1
ENST00000585517.5
ENST00000264657.10
ENST00000678048.1
ENST00000678674.1
ENST00000678913.1
ENST00000678572.1
ENST00000678906.1
signal transducer and activator of transcription 3
chr17_-_51046868 0.52 ENST00000510283.5
ENST00000510855.1
sperm associated antigen 9
chr14_+_20781139 0.52 ENST00000304677.3
ribonuclease A family member k6
chr6_-_76072654 0.51 ENST00000369950.8
ENST00000611179.4
ENST00000369963.5
interphotoreceptor matrix proteoglycan 1
chr12_-_39340963 0.51 ENST00000552961.5
kinesin family member 21A
chr19_+_38647614 0.50 ENST00000252699.7
ENST00000424234.7
ENST00000440400.2
actinin alpha 4
chr11_-_26572102 0.50 ENST00000455601.6
mucin 15, cell surface associated
chr10_+_71396905 0.49 ENST00000224721.12
ENST00000398809.9
ENST00000461841.7
ENST00000299366.11
ENST00000644511.1
ENST00000616684.4
cadherin related 23
chr4_-_48080172 0.49 ENST00000507351.1
TXK tyrosine kinase
chr5_+_129748091 0.48 ENST00000564719.2
membrane integral NOTCH2 associated receptor 2
chr3_+_130850585 0.47 ENST00000505330.5
ENST00000504381.5
ENST00000507488.6
ATPase secretory pathway Ca2+ transporting 1
chr2_-_227379297 0.47 ENST00000304568.4
transmembrane 4 L six family member 20
chr16_+_56936654 0.47 ENST00000563911.5
homocysteine inducible ER protein with ubiquitin like domain 1
chr19_+_38647679 0.47 ENST00000390009.7
ENST00000589528.1
actinin alpha 4
chr4_+_87832917 0.47 ENST00000395102.8
ENST00000497649.6
ENST00000540395.1
ENST00000560249.5
ENST00000511670.5
ENST00000361056.3
matrix extracellular phosphoglycoprotein
chr4_-_174522791 0.45 ENST00000541923.5
ENST00000542498.5
15-hydroxyprostaglandin dehydrogenase
chr17_-_43661915 0.45 ENST00000318579.9
ENST00000393661.2
mesenchyme homeobox 1
chr3_+_155080307 0.45 ENST00000360490.7
membrane metalloendopeptidase
chr17_+_62370218 0.45 ENST00000450662.7
EF-hand calcium binding domain 3
chrX_+_41689006 0.44 ENST00000378138.5
ENST00000620846.1
ENST00000649219.1
G protein-coupled receptor 34
chr10_-_92243246 0.43 ENST00000412050.8
ENST00000614585.4
cytoplasmic polyadenylation element binding protein 3
chr3_-_62373538 0.42 ENST00000283268.8
FEZ family zinc finger 2
chr12_+_53954870 0.42 ENST00000243103.4
homeobox C12
chr17_-_8119047 0.41 ENST00000318227.4
arachidonate lipoxygenase 3
chr1_-_46551647 0.41 ENST00000481882.7
kinocilin
chr3_-_196515315 0.41 ENST00000397537.3
single-pass membrane protein with coiled-coil domains 1
chr4_+_67558719 0.41 ENST00000265404.7
ENST00000396225.1
signal transducing adaptor family member 1
chr9_-_92482350 0.40 ENST00000375543.2
asporin
chr4_+_158315309 0.40 ENST00000460056.6
relaxin family peptide receptor 1
chr17_-_66220630 0.40 ENST00000585162.1
apolipoprotein H
chr17_-_40665121 0.39 ENST00000394052.5
keratin 222
chr14_+_35278618 0.39 ENST00000540871.5
proteasome 20S subunit alpha 6
chr10_+_24449426 0.39 ENST00000307544.10
KIAA1217
chr3_+_98353854 0.38 ENST00000354924.2
olfactory receptor family 5 subfamily K member 4
chr3_-_62374293 0.38 ENST00000486811.5
FEZ family zinc finger 2
chr6_-_24877262 0.37 ENST00000378023.8
ENST00000540914.5
RHO family interacting cell polarization regulator 2
chr10_-_126670686 0.37 ENST00000488181.3
chromosome 10 open reading frame 90
chr19_-_43619591 0.37 ENST00000598676.1
ENST00000300811.8
zinc finger protein 428
chr1_+_103750406 0.37 ENST00000370079.3
amylase alpha 1C
chr17_-_10549652 0.36 ENST00000245503.10
myosin heavy chain 2
chr13_-_46142834 0.36 ENST00000674665.1
lymphocyte cytosolic protein 1
chr10_+_112950586 0.35 ENST00000355717.9
ENST00000352065.10
ENST00000369395.6
ENST00000545257.6
transcription factor 7 like 2
chr5_-_134174765 0.35 ENST00000520417.1
S-phase kinase associated protein 1
chr10_+_84173793 0.34 ENST00000372126.4
chromosome 10 open reading frame 99
chr3_+_173398438 0.34 ENST00000457714.5
neuroligin 1
chr14_+_34993240 0.34 ENST00000677647.1
signal recognition particle 54
chr17_-_40822604 0.34 ENST00000269576.6
ENST00000635956.2
keratin 10
chr7_+_123601836 0.34 ENST00000434204.5
ankyrin repeat and SOCS box containing 15
chr22_-_40636664 0.34 ENST00000651595.2
ENST00000396617.7
ENST00000463769.7
myocardin related transcription factor A
chr22_-_40636689 0.34 ENST00000402042.7
ENST00000355630.10
myocardin related transcription factor A
chr2_+_167187364 0.34 ENST00000672671.1
xin actin binding repeat containing 2
chr11_+_33258304 0.33 ENST00000531504.5
ENST00000456517.2
homeodomain interacting protein kinase 3
chr1_+_27773189 0.33 ENST00000373943.9
ENST00000440806.2
syntaxin 12
chr2_+_167187283 0.32 ENST00000409605.1
ENST00000409273.6
xin actin binding repeat containing 2
chr17_-_52158678 0.32 ENST00000451037.7
carbonic anhydrase 10
chr17_+_7627963 0.31 ENST00000575729.5
ENST00000340624.9
sex hormone binding globulin
chrX_-_120311533 0.31 ENST00000440464.5
ENST00000519908.1
transmembrane protein 255A
chr1_-_2526585 0.31 ENST00000378466.9
ENST00000435556.8
pantothenate kinase 4 (inactive)
chr20_+_31968141 0.30 ENST00000562532.3
XK related 7
chr5_+_141121793 0.30 ENST00000194152.4
protocadherin beta 4
chr7_-_13986439 0.30 ENST00000443608.5
ENST00000438956.5
ETS variant transcription factor 1
chr6_-_136525961 0.30 ENST00000438100.6
microtubule associated protein 7
chr17_-_40937445 0.30 ENST00000436344.7
ENST00000485751.1
keratin 23
chr1_+_6045914 0.30 ENST00000378083.7
potassium voltage-gated channel subfamily A regulatory beta subunit 2
chr1_+_100538131 0.30 ENST00000315033.5
G protein-coupled receptor 88
chr5_-_79514127 0.29 ENST00000334082.11
homer scaffold protein 1
chr15_-_76012390 0.28 ENST00000394907.8
neuregulin 4
chr4_+_145482761 0.28 ENST00000507367.1
ENST00000394092.6
ENST00000515385.1
SMAD family member 1
chr16_+_1678271 0.28 ENST00000562684.5
ENST00000561516.5
ENST00000248098.8
ENST00000382711.9
ENST00000566742.5
Jupiter microtubule associated homolog 2
chr12_-_51217671 0.28 ENST00000333640.11
ENST00000550824.6
POU class 6 homeobox 1
chr2_+_90021567 0.28 ENST00000436451.2
immunoglobulin kappa variable 6D-21 (non-functional)
chr13_+_108596152 0.27 ENST00000356711.7
ENST00000251041.10
myosin XVI
chr8_-_25424260 0.27 ENST00000421054.7
gonadotropin releasing hormone 1
chr16_+_7332744 0.27 ENST00000436368.6
ENST00000311745.9
ENST00000340209.8
ENST00000620507.4
RNA binding fox-1 homolog 1
chr4_+_61202142 0.27 ENST00000514591.5
adhesion G protein-coupled receptor L3
chrX_+_15507302 0.27 ENST00000342014.6
BMX non-receptor tyrosine kinase
chr6_-_32407123 0.27 ENST00000374993.4
ENST00000544175.2
ENST00000454136.7
ENST00000446536.2
butyrophilin like 2
chr1_+_167220870 0.26 ENST00000367866.7
ENST00000429375.6
ENST00000541643.7
POU class 2 homeobox 1
chr8_-_66178455 0.26 ENST00000276571.5
corticotropin releasing hormone
chr17_+_7484357 0.26 ENST00000674977.2
RNA polymerase II subunit A
chrX_-_124963768 0.26 ENST00000371130.7
ENST00000422452.2
teneurin transmembrane protein 1
chr1_+_50108856 0.26 ENST00000650764.1
ENST00000494555.2
ENST00000371824.7
ENST00000371823.8
ENST00000652693.1
ELAV like RNA binding protein 4
chr12_-_100092890 0.26 ENST00000550544.5
ENST00000551980.1
ENST00000548045.5
ENST00000545232.6
ENST00000551973.5
UHRF1 binding protein 1 like
chr3_+_160225409 0.26 ENST00000326474.5
chromosome 3 open reading frame 80
chr14_-_64942783 0.25 ENST00000612794.1
glutathione peroxidase 2
chr2_-_73779968 0.25 ENST00000452812.1
ENST00000443070.5
ENST00000272444.7
dual specificity phosphatase 11
chr8_-_90082871 0.25 ENST00000265431.7
calbindin 1
chr20_-_7940444 0.25 ENST00000378789.4
hydroxyacid oxidase 1
chr16_+_74999003 0.25 ENST00000335325.9
ENST00000320619.10
zinc and ring finger 1
chr19_-_8308287 0.25 ENST00000537716.6
ENST00000301458.10
CD320 molecule
chr4_+_154563003 0.25 ENST00000302068.9
ENST00000509493.1
fibrinogen beta chain
chrX_+_15500800 0.24 ENST00000348343.11
BMX non-receptor tyrosine kinase
chr19_-_18522051 0.24 ENST00000262809.9
elongation factor for RNA polymerase II
chr9_-_92482499 0.24 ENST00000375544.7
asporin
chr14_-_64942720 0.24 ENST00000557049.1
ENST00000389614.6
glutathione peroxidase 2
chr5_+_141402764 0.24 ENST00000573521.2
ENST00000616887.1
protocadherin gamma subfamily A, 9
chr20_+_45361936 0.24 ENST00000372727.5
ENST00000414310.5
SYS1 golgi trafficking protein
chr9_-_91423819 0.24 ENST00000297689.4
nuclear factor, interleukin 3 regulated
chr17_+_29941605 0.24 ENST00000394835.7
EF-hand calcium binding domain 5
chr2_+_184598520 0.24 ENST00000302277.7
zinc finger protein 804A
chr10_-_30629741 0.23 ENST00000647634.2
ENST00000375318.4
lysozyme like 2
chr20_+_59604527 0.23 ENST00000371015.6
phosphatase and actin regulator 3
chr16_-_21303036 0.23 ENST00000219599.8
ENST00000576703.5
crystallin mu
chrX_+_78747705 0.23 ENST00000614823.5
ENST00000435339.3
ENST00000514744.5
lysophosphatidic acid receptor 4
chr13_-_102759059 0.23 ENST00000322527.4
coiled-coil domain containing 168
chr10_-_88952763 0.23 ENST00000224784.10
actin alpha 2, smooth muscle
chr6_+_30163188 0.23 ENST00000619857.4
tripartite motif containing 15
chr2_-_223838022 0.23 ENST00000444408.1
adaptor related protein complex 1 subunit sigma 3
chr6_+_26272923 0.23 ENST00000377733.4
H2B clustered histone 10

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.4 1.1 GO:1902728 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730) positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
0.3 1.0 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.3 1.4 GO:1903860 negative regulation of dendrite extension(GO:1903860) regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800) negative regulation of branching morphogenesis of a nerve(GO:2000173)
0.3 2.7 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.2 1.0 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.2 0.9 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.2 1.8 GO:0060574 intestinal epithelial cell maturation(GO:0060574)
0.2 1.6 GO:0051177 meiotic sister chromatid cohesion(GO:0051177)
0.1 0.9 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1 3.9 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.1 0.4 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.1 0.6 GO:0098886 modification of dendritic spine(GO:0098886)
0.1 1.0 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417) positive regulation of pinocytosis(GO:0048549)
0.1 0.4 GO:1903973 negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973)
0.1 2.6 GO:0008228 opsonization(GO:0008228)
0.1 0.6 GO:0010841 positive regulation of circadian sleep/wake cycle, wakefulness(GO:0010841)
0.1 1.8 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.1 1.5 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.1 2.9 GO:0071420 cellular response to histamine(GO:0071420)
0.1 0.8 GO:0098728 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.1 1.5 GO:0070170 regulation of tooth mineralization(GO:0070170)
0.1 1.8 GO:0045475 locomotor rhythm(GO:0045475)
0.1 1.1 GO:0060235 voluntary musculoskeletal movement(GO:0050882) lens induction in camera-type eye(GO:0060235)
0.1 0.8 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 0.1 GO:2000439 positive regulation of monocyte extravasation(GO:2000439)
0.1 0.5 GO:0001757 somite specification(GO:0001757)
0.1 0.3 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.1 1.8 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 0.3 GO:0098507 polynucleotide 5' dephosphorylation(GO:0098507)
0.1 0.5 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.1 0.5 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.1 0.2 GO:1901253 mesodermal cell fate determination(GO:0007500) negative regulation of intracellular transport of viral material(GO:1901253)
0.1 0.2 GO:0097252 oligodendrocyte apoptotic process(GO:0097252)
0.1 0.5 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.1 0.4 GO:2001107 negative regulation of establishment of T cell polarity(GO:1903904) negative regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001107)
0.1 0.3 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.1 1.0 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.1 2.3 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 1.2 GO:0001778 plasma membrane repair(GO:0001778)
0.1 0.7 GO:0035524 proline transmembrane transport(GO:0035524)
0.1 0.2 GO:0072095 regulation of branch elongation involved in ureteric bud branching(GO:0072095)
0.1 0.2 GO:0072144 glomerular mesangial cell development(GO:0072144)
0.1 0.5 GO:0001865 NK T cell differentiation(GO:0001865)
0.1 0.2 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.1 0.3 GO:2000354 regulation of ovarian follicle development(GO:2000354)
0.1 2.1 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.0 0.3 GO:0061743 motor learning(GO:0061743)
0.0 0.5 GO:0050957 equilibrioception(GO:0050957)
0.0 0.4 GO:0051121 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.5 GO:2001300 lipoxin metabolic process(GO:2001300)
0.0 0.4 GO:0071492 cellular response to UV-A(GO:0071492)
0.0 1.5 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.2 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0 0.6 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.3 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.6 GO:0032096 negative regulation of response to food(GO:0032096) negative regulation of appetite(GO:0032099)
0.0 0.3 GO:0070995 NADPH oxidation(GO:0070995)
0.0 1.6 GO:1903859 regulation of dendrite extension(GO:1903859) positive regulation of dendrite extension(GO:1903861)
0.0 0.2 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.1 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.0 0.4 GO:0051918 negative regulation of fibrinolysis(GO:0051918)
0.0 0.1 GO:0034085 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0 1.9 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.3 GO:0035502 metanephric part of ureteric bud development(GO:0035502)
0.0 0.3 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 1.5 GO:0061014 positive regulation of mRNA catabolic process(GO:0061014)
0.0 0.2 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.2 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 0.5 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.0 0.6 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 4.5 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.1 GO:0090467 L-arginine import(GO:0043091) arginine import(GO:0090467)
0.0 0.1 GO:1901420 negative regulation of response to alcohol(GO:1901420)
0.0 0.5 GO:0070168 negative regulation of biomineral tissue development(GO:0070168)
0.0 0.2 GO:0070857 regulation of bile acid biosynthetic process(GO:0070857)
0.0 0.3 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.0 0.3 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.0 0.5 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.1 GO:0034343 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344) positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0 0.2 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.4 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.2 GO:1903546 receptor localization to nonmotile primary cilium(GO:0097500) protein localization to photoreceptor outer segment(GO:1903546)
0.0 0.1 GO:0033184 positive regulation of histone ubiquitination(GO:0033184)
0.0 0.2 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 1.0 GO:0034142 toll-like receptor 4 signaling pathway(GO:0034142)
0.0 0.7 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 0.8 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.8 GO:0039703 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.0 0.3 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.0 0.2 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.1 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.0 0.2 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.2 GO:0030656 cobalamin transport(GO:0015889) regulation of vitamin metabolic process(GO:0030656)
0.0 0.2 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 1.2 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.3 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.5 GO:0019731 antibacterial humoral response(GO:0019731)
0.0 0.4 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 0.2 GO:0042359 vitamin D metabolic process(GO:0042359)
0.0 1.6 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.2 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.0 0.1 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.6 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.8 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.0 0.2 GO:0006069 ethanol oxidation(GO:0006069)
0.0 0.3 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.2 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.3 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.1 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.0 0.2 GO:0046838 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.0 1.1 GO:0070373 negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.0 0.2 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.3 GO:0050832 defense response to fungus(GO:0050832)
0.0 0.2 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.6 GO:1901998 toxin transport(GO:1901998)
0.0 0.2 GO:0051601 exocyst localization(GO:0051601)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0005600 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.4 1.9 GO:0070557 PCNA-p21 complex(GO:0070557)
0.2 0.6 GO:0097444 spine apparatus(GO:0097444)
0.2 1.2 GO:0005826 actomyosin contractile ring(GO:0005826)
0.1 0.8 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.1 1.5 GO:0071438 invadopodium membrane(GO:0071438)
0.1 8.1 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 2.6 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 0.3 GO:1990423 RZZ complex(GO:1990423)
0.1 0.4 GO:0032437 cuticular plate(GO:0032437)
0.1 1.5 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.1 2.9 GO:1902711 GABA-A receptor complex(GO:1902711)
0.1 0.5 GO:1990037 Lewy body core(GO:1990037)
0.1 3.3 GO:0030673 axolemma(GO:0030673)
0.1 0.3 GO:1990031 pinceau fiber(GO:1990031)
0.1 0.8 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.3 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.0 0.2 GO:0035363 histone locus body(GO:0035363)
0.0 1.8 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.2 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.7 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 1.2 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.3 GO:0048500 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0 0.4 GO:0060171 stereocilium membrane(GO:0060171)
0.0 0.3 GO:0043196 varicosity(GO:0043196)
0.0 0.9 GO:0031143 pseudopodium(GO:0031143)
0.0 0.4 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.2 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 1.6 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.1 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 2.8 GO:0005901 caveola(GO:0005901)
0.0 0.1 GO:0008278 cohesin complex(GO:0008278)
0.0 0.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.0 2.1 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 0.3 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.4 GO:0042627 chylomicron(GO:0042627)
0.0 0.3 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.3 GO:0071141 SMAD protein complex(GO:0071141)
0.0 1.1 GO:0035580 specific granule lumen(GO:0035580)
0.0 0.5 GO:0032420 stereocilium(GO:0032420)
0.0 0.7 GO:0031941 filamentous actin(GO:0031941)
0.0 1.5 GO:0016605 PML body(GO:0016605)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.9 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.3 3.9 GO:0033691 sialic acid binding(GO:0033691)
0.3 2.9 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.3 2.1 GO:0071532 ankyrin repeat binding(GO:0071532)
0.3 1.8 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.2 1.4 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.2 0.9 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 0.9 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 2.7 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 1.8 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 1.1 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.1 1.5 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.1 0.7 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.1 3.1 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 0.5 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 0.5 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.1 0.3 GO:0004651 polynucleotide 5'-phosphatase activity(GO:0004651)
0.1 0.3 GO:0052854 (S)-2-hydroxy-acid oxidase activity(GO:0003973) very-long-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052852) long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity(GO:0052853) medium-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052854)
0.1 0.4 GO:0051120 hepoxilin A3 synthase activity(GO:0051120)
0.1 1.5 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 1.1 GO:0046790 virion binding(GO:0046790)
0.1 1.8 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.7 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 0.4 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.1 0.3 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.1 0.7 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 0.4 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.1 0.2 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.0 1.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.3 GO:0005497 androgen binding(GO:0005497)
0.0 0.2 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 0.3 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.3 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.2 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.5 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.2 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.3 GO:0005499 vitamin D binding(GO:0005499)
0.0 1.0 GO:0008242 omega peptidase activity(GO:0008242)
0.0 0.1 GO:0032427 GBD domain binding(GO:0032427)
0.0 0.6 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.2 GO:0015235 cobalamin transporter activity(GO:0015235)
0.0 0.1 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.0 0.6 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 1.2 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.6 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.3 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 4.5 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.2 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 0.1 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.0 0.1 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.0 0.2 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 1.0 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.1 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.0 0.2 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0 0.2 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.6 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.3 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.4 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.3 GO:0070878 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618) primary miRNA binding(GO:0070878)
0.0 1.0 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.0 0.8 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.8 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.2 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.0 0.2 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.0 1.0 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 0.3 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.1 GO:0031208 POZ domain binding(GO:0031208)
0.0 0.2 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.3 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 0.5 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.5 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.5 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.1 GO:0030345 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0 0.3 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.4 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 1.0 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.5 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.2 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.5 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 1.2 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.3 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.2 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.2 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 4.3 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.1 1.1 ST STAT3 PATHWAY STAT3 Pathway
0.1 3.0 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 5.1 PID ATF2 PATHWAY ATF-2 transcription factor network
0.1 2.0 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.3 NABA COLLAGENS Genes encoding collagen proteins
0.0 1.2 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.9 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.6 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 1.0 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 1.3 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.8 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.3 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.8 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.8 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 0.4 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.3 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.2 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.3 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.6 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 1.9 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.1 2.9 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 3.2 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 1.8 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.1 2.1 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 2.3 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 1.5 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 1.2 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 2.0 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 1.1 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 2.1 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 1.0 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 2.4 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.8 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 1.0 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.3 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.5 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.3 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.3 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 4.2 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.2 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.0 0.4 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.7 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.2 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 1.3 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.2 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.4 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 1.9 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.5 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.3 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.2 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression