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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for PRDM14

Z-value: 0.25

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Transcription factors associated with PRDM14

Gene Symbol Gene ID Gene Info
ENSG00000147596.4 PRDM14

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PRDM14hg38_v1_chr8_-_70071226_700712580.038.9e-01Click!

Activity profile of PRDM14 motif

Sorted Z-values of PRDM14 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of PRDM14

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr19_-_50513870 0.27 ENST00000389208.9
aspartate dehydrogenase domain containing
chr5_-_160685379 0.25 ENST00000642502.1
ATPase phospholipid transporting 10B (putative)
chrX_+_120158600 0.20 ENST00000371388.5
Rhox homeobox family member 2
chrX_-_120077690 0.20 ENST00000371402.5
Rhox homeobox family member 2B
chr5_-_16936231 0.18 ENST00000507288.1
ENST00000274203.13
ENST00000513610.6
myosin X
chr1_-_155033778 0.18 ENST00000368424.4
DC-STAMP domain containing 2
chr12_+_121210160 0.17 ENST00000542067.5
purinergic receptor P2X 4
chr12_+_121210065 0.17 ENST00000359949.11
ENST00000337233.9
ENST00000538701.5
purinergic receptor P2X 4
chr18_+_59899988 0.17 ENST00000316660.7
ENST00000269518.9
phorbol-12-myristate-13-acetate-induced protein 1
chr17_-_19748285 0.16 ENST00000570414.1
ENST00000225740.11
aldehyde dehydrogenase 3 family member A1
chr17_-_19748341 0.15 ENST00000395555.7
aldehyde dehydrogenase 3 family member A1
chr17_-_19748355 0.14 ENST00000494157.6
aldehyde dehydrogenase 3 family member A1
chr12_+_64497968 0.12 ENST00000676593.1
ENST00000677093.1
TANK binding kinase 1
novel transcript
chr12_+_3491189 0.12 ENST00000382622.4
protein arginine methyltransferase 8
chr11_+_62707668 0.12 ENST00000294117.6
G protein subunit gamma 3
chr17_+_38717424 0.11 ENST00000615858.1
MLLT6, PHD finger containing
chr6_+_31946086 0.11 ENST00000425368.7
complement factor B
chr10_+_88664439 0.10 ENST00000394375.7
ENST00000608620.5
ENST00000238983.9
ENST00000355843.2
lipase F, gastric type
chr9_+_84668485 0.10 ENST00000359847.4
ENST00000395882.6
ENST00000376208.6
ENST00000376213.6
neurotrophic receptor tyrosine kinase 2
chr5_-_24644968 0.10 ENST00000264463.8
cadherin 10
chr1_-_182672882 0.09 ENST00000367557.8
ENST00000258302.8
regulator of G protein signaling 8
chr11_-_106022209 0.09 ENST00000301919.9
ENST00000534458.1
ENST00000530108.1
ENST00000530788.1
Myb/SANT DNA binding domain containing 4 with coiled-coils
chr3_-_71132099 0.09 ENST00000650188.1
ENST00000648121.1
ENST00000648794.1
ENST00000649592.1
forkhead box P1
chr2_-_68871382 0.09 ENST00000295379.2
bone morphogenetic protein 10
chr1_+_36155930 0.08 ENST00000316156.8
MAP7 domain containing 1
chr4_-_10457385 0.08 ENST00000507515.1
ENST00000326756.4
zinc finger protein 518B
chr12_+_54008961 0.08 ENST00000040584.6
homeobox C8
chr1_+_155033824 0.08 ENST00000295542.6
ENST00000423025.6
ENST00000368419.2
DC-STAMP domain containing 1
chr4_+_80266639 0.08 ENST00000456523.3
ENST00000312465.12
fibroblast growth factor 5
chr5_-_136193143 0.08 ENST00000607574.2
small integral membrane protein 32
chr13_+_108629605 0.07 ENST00000457511.7
myosin XVI
chr7_-_44541318 0.07 ENST00000381160.8
NPC1 like intracellular cholesterol transporter 1
chr1_+_21570303 0.07 ENST00000374830.2
alkaline phosphatase, biomineralization associated
chr10_+_12129637 0.07 ENST00000379051.5
ENST00000379033.7
ENST00000441368.5
ENST00000298428.14
ENST00000304267.12
ENST00000379020.8
ENST00000379017.7
SEC61 translocon subunit alpha 2
chr12_-_48957445 0.07 ENST00000541959.5
ENST00000447318.6
ENST00000256682.9
ADP ribosylation factor 3
chr5_+_32711313 0.07 ENST00000265074.13
natriuretic peptide receptor 3
chr1_-_167914089 0.07 ENST00000476818.2
ENST00000367848.1
ENST00000367851.9
ENST00000545172.5
adenylate cyclase 10
chr14_-_21023954 0.07 ENST00000554094.5
NDRG family member 2
chr14_-_21024092 0.06 ENST00000554398.5
NDRG family member 2
chr15_+_74788542 0.06 ENST00000567571.5
C-terminal Src kinase
chr1_-_41918858 0.06 ENST00000372583.6
HIVEP zinc finger 3
chr16_-_53703883 0.06 ENST00000262135.9
ENST00000564374.5
ENST00000566096.5
RPGRIP1 like
chr3_-_155676363 0.06 ENST00000494598.5
phospholipase C eta 1
chr1_-_41918666 0.05 ENST00000372584.5
HIVEP zinc finger 3
chr16_-_53703810 0.05 ENST00000569716.1
ENST00000562588.5
ENST00000621565.5
ENST00000562230.5
ENST00000563746.5
ENST00000568653.7
ENST00000647211.2
RPGRIP1 like
chr12_-_48957365 0.05 ENST00000398092.4
ENST00000539611.1
novel protein
ADP ribosylation factor 3
chr1_-_153113507 0.05 ENST00000468739.2
small proline rich protein 2F
chr2_-_227379297 0.05 ENST00000304568.4
transmembrane 4 L six family member 20
chr1_-_6261053 0.05 ENST00000377893.3
G protein-coupled receptor 153
chr3_+_156120572 0.05 ENST00000389636.9
ENST00000490337.6
potassium voltage-gated channel subfamily A member regulatory beta subunit 1
chr11_-_65856944 0.04 ENST00000524553.5
cofilin 1
chr17_+_49575828 0.04 ENST00000328741.6
neurexophilin 3
chr11_-_65857007 0.04 ENST00000527344.5
cofilin 1
chr1_+_50105666 0.04 ENST00000651347.1
ELAV like RNA binding protein 4
chr11_+_15114912 0.04 ENST00000379556.8
INSC spindle orientation adaptor protein
chr19_+_42284483 0.04 ENST00000575354.6
capicua transcriptional repressor
chr20_-_50153637 0.04 ENST00000341698.2
ENST00000371652.9
ENST00000371650.9
PEDS1-UBE2V1 readthrough
plasmanylethanolamine desaturase 1
chr7_-_30026617 0.04 ENST00000222803.10
FKBP prolyl isomerase 14
chr7_+_39950013 0.03 ENST00000340829.10
cyclin dependent kinase 13
chr17_-_17582417 0.03 ENST00000395783.5
phosphatidylethanolamine N-methyltransferase
chr7_-_124765753 0.03 ENST00000303921.3
G protein-coupled receptor 37
chr1_+_27342014 0.03 ENST00000618673.4
ENST00000318074.9
ENST00000616558.5
synaptotagmin like 1
chr1_+_50106265 0.03 ENST00000357083.8
ELAV like RNA binding protein 4
chr1_-_113887375 0.03 ENST00000471267.1
ENST00000393320.3
BCL2 like 15
chr7_-_44541262 0.03 ENST00000289547.8
ENST00000546276.5
ENST00000423141.1
NPC1 like intracellular cholesterol transporter 1
chr17_-_48615261 0.03 ENST00000239144.5
homeobox B8
chr6_-_46080332 0.02 ENST00000185206.12
chloride intracellular channel 5
chr11_+_86245050 0.02 ENST00000673233.2
ENST00000327320.8
ENST00000351625.10
ENST00000534595.1
embryonic ectoderm development
chr5_-_168883333 0.02 ENST00000404867.7
slit guidance ligand 3
chr2_-_144520315 0.02 ENST00000465070.5
ENST00000465308.5
ENST00000636471.1
ENST00000629520.2
ENST00000675069.1
ENST00000636026.2
ENST00000444559.5
zinc finger E-box binding homeobox 2
chr7_+_39950187 0.02 ENST00000181839.10
cyclin dependent kinase 13
chrX_+_15507302 0.02 ENST00000342014.6
BMX non-receptor tyrosine kinase
chr17_+_77453993 0.02 ENST00000592951.5
septin 9
chr17_+_41837817 0.01 ENST00000438813.1
ENST00000293303.5
kelch like family member 10
chrX_+_51893533 0.01 ENST00000375722.5
ENST00000326587.12
ENST00000375695.2
MAGE family member D1
chr5_+_32710630 0.01 ENST00000326958.5
natriuretic peptide receptor 3
chr11_-_46593948 0.00 ENST00000533727.5
ENST00000534300.5
ENST00000683756.1
ENST00000528950.1
ENST00000526606.1
autophagy and beclin 1 regulator 1
chrX_+_41334154 0.00 ENST00000441189.4
ENST00000644513.1
ENST00000644109.1
ENST00000646122.1
ENST00000644074.1
ENST00000644876.2
ENST00000399959.7
ENST00000646319.1
DEAD-box helicase 3 X-linked

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0019364 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.0 0.1 GO:0099540 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
0.0 0.3 GO:0032308 regulation of prostaglandin secretion(GO:0032306) positive regulation of prostaglandin secretion(GO:0032308)
0.0 0.1 GO:0071529 cementum mineralization(GO:0071529)
0.0 0.1 GO:0044565 dendritic cell proliferation(GO:0044565)
0.0 0.1 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
0.0 0.1 GO:0071964 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814)
0.0 0.1 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0 0.2 GO:0010917 negative regulation of mitochondrial membrane potential(GO:0010917)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.1 GO:0002945 cyclin K-CDK13 complex(GO:0002945)
0.0 0.1 GO:0005879 axonemal microtubule(GO:0005879)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0 0.1 GO:0031862 prostanoid receptor binding(GO:0031862)
0.0 0.1 GO:0060175 brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.0 0.3 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.1 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0 0.2 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 0.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.0 GO:0004608 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.0 0.1 GO:0004035 alkaline phosphatase activity(GO:0004035)