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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for PRRX1_ALX4_PHOX2A

Z-value: 0.43

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Transcription factors associated with PRRX1_ALX4_PHOX2A

Gene Symbol Gene ID Gene Info
PRRX1
ENSG00000116132.12 PRRX1
ALX4
ENSG00000052850.8 ALX4
PHOX2A
ENSG00000165462.5 PHOX2A

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PRRX1hg38_v1_chr1_+_170664121_170664144-0.358.3e-02Click!
ALX4hg38_v1_chr11_-_44310126_443101520.301.5e-01Click!
PHOX2Ahg38_v1_chr11_-_72241192_72241275,
hg38_v1_chr11_-_72244166_72244184		-0.067.9e-01Click!

Activity profile of PRRX1_ALX4_PHOX2A motif

Sorted Z-values of PRRX1_ALX4_PHOX2A motif

Network of associatons between targets according to the STRING database.

First level regulatory network of PRRX1_ALX4_PHOX2A

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr1_-_91906280 1.83 ENST00000370399.6
TGFBR3
transforming growth factor beta receptor 3
chr1_+_84181630 1.23 ENST00000610457.1
PRKACB
protein kinase cAMP-activated catalytic subunit beta
chr2_+_178320228 0.82 ENST00000315022.2
OSBPL6
oxysterol binding protein like 6
chr6_-_75363003 0.78 ENST00000370020.1
FILIP1
filamin A interacting protein 1
chr3_-_27722699 0.68 ENST00000461503.2
EOMES
eomesodermin
chr9_-_123184233 0.60 ENST00000447404.6
STRBP
spermatid perinuclear RNA binding protein
chr3_-_125055987 0.52 ENST00000311127.9
HEG1
heart development protein with EGF like domains 1
chr18_+_616711 0.51 ENST00000579494.1
CLUL1
clusterin like 1
chr18_+_616672 0.50 ENST00000338387.11
CLUL1
clusterin like 1
chr10_+_68106109 0.47 ENST00000540630.5
ENST00000354393.6
MYPN
myopalladin
chr3_-_27722316 0.47 ENST00000449599.4
EOMES
eomesodermin
chr1_+_84164962 0.47 ENST00000614872.4
ENST00000394839.6
PRKACB
protein kinase cAMP-activated catalytic subunit beta
chr5_-_111976925 0.46 ENST00000395634.7
NREP
neuronal regeneration related protein
chr3_-_18438767 0.45 ENST00000454909.6
SATB1
SATB homeobox 1
chr5_-_111758061 0.45 ENST00000509979.5
ENST00000513100.5
ENST00000508161.5
ENST00000455559.6
NREP
neuronal regeneration related protein
chr2_-_218010202 0.44 ENST00000646520.1
TNS1
tensin 1
chr1_-_93681829 0.43 ENST00000260502.11
BCAR3
BCAR3 adaptor protein, NSP family member
chr8_-_92095215 0.42 ENST00000360348.6
ENST00000520428.5
ENST00000518992.5
ENST00000520556.5
ENST00000518317.5
ENST00000521319.5
ENST00000521375.5
ENST00000518449.5
ENST00000613886.4
RUNX1T1
RUNX1 partner transcriptional co-repressor 1
chr3_-_142029108 0.41 ENST00000497579.5
TFDP2
transcription factor Dp-2
chr10_+_35175586 0.40 ENST00000494479.5
ENST00000463314.5
ENST00000342105.7
ENST00000495301.1
CREM
cAMP responsive element modulator
chr6_-_132659178 0.39 ENST00000275216.3
TAAR1
trace amine associated receptor 1
chr2_-_55334529 0.39 ENST00000645860.1
ENST00000642563.1
ENST00000647396.1
CCDC88A
coiled-coil domain containing 88A
chr6_+_116369837 0.38 ENST00000645988.1
DSE
dermatan sulfate epimerase
chr17_-_40994159 0.34 ENST00000391586.3
KRTAP3-3
keratin associated protein 3-3
chr9_+_133636355 0.34 ENST00000393056.8
DBH
dopamine beta-hydroxylase
chr2_-_55269038 0.29 ENST00000417363.5
ENST00000412530.1
ENST00000366137.6
ENST00000420637.5
MTIF2
mitochondrial translational initiation factor 2
chr12_+_19205294 0.29 ENST00000424268.5
PLEKHA5
pleckstrin homology domain containing A5
chr1_-_21050952 0.28 ENST00000264211.12
EIF4G3
eukaryotic translation initiation factor 4 gamma 3
chr3_+_98149326 0.27 ENST00000437310.1
OR5H14
olfactory receptor family 5 subfamily H member 14
chr6_+_30914205 0.26 ENST00000672801.1
ENST00000321897.9
ENST00000625423.2
ENST00000676266.1
ENST00000428017.5
VARS2
valyl-tRNA synthetase 2, mitochondrial
chr18_+_44700796 0.26 ENST00000677130.1
SETBP1
SET binding protein 1
chr6_+_30914329 0.25 ENST00000541562.6
VARS2
valyl-tRNA synthetase 2, mitochondrial
chr9_+_128566741 0.25 ENST00000630866.1
SPTAN1
spectrin alpha, non-erythrocytic 1
chr2_-_182427014 0.24 ENST00000409365.5
ENST00000351439.9
PDE1A
phosphodiesterase 1A
chr12_-_7503744 0.24 ENST00000396620.7
ENST00000432237.3
CD163
CD163 molecule
chr12_-_91153149 0.24 ENST00000550758.1
DCN
decorin
chr20_+_36091409 0.23 ENST00000202028.9
EPB41L1
erythrocyte membrane protein band 4.1 like 1
chr3_-_151316795 0.23 ENST00000260843.5
GPR87
G protein-coupled receptor 87
chr14_+_22516273 0.23 ENST00000390510.1
TRAJ27
T cell receptor alpha joining 27
chr2_-_201739205 0.22 ENST00000681558.1
ENST00000681495.1
ALS2
alsin Rho guanine nucleotide exchange factor ALS2
chr6_+_121437378 0.21 ENST00000650427.1
ENST00000647564.1
GJA1
gap junction protein alpha 1
chr5_-_67196791 0.21 ENST00000256447.5
CD180
CD180 molecule
chr2_+_189857393 0.21 ENST00000452382.1
PMS1
PMS1 homolog 1, mismatch repair system component
chr5_+_36606355 0.21 ENST00000681909.1
ENST00000513903.5
ENST00000681795.1
ENST00000680125.1
ENST00000612708.5
ENST00000680232.1
ENST00000681776.1
ENST00000681926.1
ENST00000679958.1
ENST00000265113.9
ENST00000504121.5
ENST00000512374.1
ENST00000613445.5
ENST00000679983.1
SLC1A3
solute carrier family 1 member 3
chr9_-_14314519 0.21 ENST00000397581.6
NFIB
nuclear factor I B
chrX_+_77910656 0.21 ENST00000343533.9
ENST00000341514.11
ENST00000645454.1
ENST00000642651.1
ENST00000644362.1
ATP7A
PGK1
ATPase copper transporting alpha
phosphoglycerate kinase 1
chr21_-_34526815 0.20 ENST00000492600.1
RCAN1
regulator of calcineurin 1
chr9_-_14314567 0.20 ENST00000397579.6
NFIB
nuclear factor I B
chr12_-_106987068 0.20 ENST00000548101.1
ENST00000550496.1
ENST00000552029.1
MTERF2
mitochondrial transcription termination factor 2
chr5_-_55173173 0.20 ENST00000296733.5
ENST00000322374.10
ENST00000381375.7
CDC20B
cell division cycle 20B
chr4_-_142305826 0.19 ENST00000514525.1
INPP4B
inositol polyphosphate-4-phosphatase type II B
chr12_-_7503841 0.18 ENST00000359156.8
CD163
CD163 molecule
chr12_+_20815672 0.18 ENST00000261196.6
ENST00000381541.7
ENST00000540229.1
SLCO1B3
SLCO1B3-SLCO1B7
solute carrier organic anion transporter family member 1B3
SLCO1B3-SLCO1B7 readthrough
chr14_-_37595224 0.18 ENST00000250448.5
FOXA1
forkhead box A1
chr20_+_33235987 0.18 ENST00000375422.6
ENST00000375413.8
ENST00000354297.9
BPIFA1
BPI fold containing family A member 1
chr11_+_66509079 0.18 ENST00000419755.3
ENSG00000256349.1
novel protein
chr9_+_2159672 0.18 ENST00000634343.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr11_-_40294089 0.17 ENST00000278198.2
LRRC4C
leucine rich repeat containing 4C
chr15_+_57219411 0.17 ENST00000543579.5
ENST00000537840.5
ENST00000343827.7
TCF12
transcription factor 12
chr12_-_106987131 0.17 ENST00000240050.9
ENST00000392830.6
MTERF2
mitochondrial transcription termination factor 2
chr7_+_148590760 0.17 ENST00000307003.3
C7orf33
chromosome 7 open reading frame 33
chr12_-_91179472 0.17 ENST00000550099.5
ENST00000546391.5
DCN
decorin
chr6_-_41071825 0.17 ENST00000468811.5
OARD1
O-acyl-ADP-ribose deacylase 1
chr15_+_75336018 0.17 ENST00000567195.5
COMMD4
COMM domain containing 4
chr16_+_68085344 0.16 ENST00000575270.5
ENST00000346183.8
NFATC3
nuclear factor of activated T cells 3
chr21_-_34526850 0.16 ENST00000481448.5
ENST00000381132.6
RCAN1
regulator of calcineurin 1
chr6_+_27824084 0.16 ENST00000355057.3
H4C11
H4 clustered histone 11
chr4_-_99435396 0.16 ENST00000209665.8
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr11_+_108116688 0.15 ENST00000672284.1
ACAT1
acetyl-CoA acetyltransferase 1
chr1_-_165445220 0.15 ENST00000619224.1
RXRG
retinoid X receptor gamma
chr13_+_53028806 0.15 ENST00000219022.3
OLFM4
olfactomedin 4
chr18_-_55321986 0.14 ENST00000570287.6
TCF4
transcription factor 4
chr2_-_58241259 0.14 ENST00000481670.2
ENST00000403676.5
ENST00000427708.6
ENST00000403295.7
ENST00000233741.9
ENST00000446381.5
ENST00000417361.1
ENST00000402135.7
ENST00000449070.5
FANCL
FA complementation group L
chr8_-_6563409 0.14 ENST00000325203.9
ANGPT2
angiopoietin 2
chr16_+_68085420 0.14 ENST00000349223.9
NFATC3
nuclear factor of activated T cells 3
chr1_-_68232514 0.14 ENST00000262348.9
ENST00000370973.2
ENST00000370971.1
WLS
Wnt ligand secretion mediator
chr19_-_7021431 0.14 ENST00000636986.2
ENST00000637800.1
MBD3L2B
methyl-CpG binding domain protein 3 like 2B
chrX_-_19799751 0.14 ENST00000379698.8
SH3KBP1
SH3 domain containing kinase binding protein 1
chr1_-_165445088 0.14 ENST00000359842.10
RXRG
retinoid X receptor gamma
chr9_+_2159850 0.14 ENST00000416751.2
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr12_-_23584600 0.14 ENST00000396007.6
SOX5
SRY-box transcription factor 5
chr6_+_26087417 0.14 ENST00000357618.10
ENST00000309234.10
HFE
homeostatic iron regulator
chr20_+_16748358 0.13 ENST00000246081.3
OTOR
otoraplin
chr13_+_57140918 0.13 ENST00000377931.1
ENST00000614894.4
PRR20A
PRR20C
proline rich 20A
proline rich 20C
chr18_-_55322215 0.13 ENST00000457482.7
TCF4
transcription factor 4
chr15_-_52678560 0.13 ENST00000562351.2
ENST00000261844.11
ENST00000399202.8
ENST00000562135.5
FAM214A
family with sequence similarity 214 member A
chr19_-_11346228 0.13 ENST00000588560.5
ENST00000592952.5
TMEM205
transmembrane protein 205
chr22_-_28306645 0.13 ENST00000612946.4
TTC28
tetratricopeptide repeat domain 28
chr8_-_85341659 0.13 ENST00000522389.5
CA1
carbonic anhydrase 1
chr4_+_185204237 0.12 ENST00000618785.4
ENST00000504273.5
SNX25
sorting nexin 25
chr16_+_68085552 0.12 ENST00000329524.8
NFATC3
nuclear factor of activated T cells 3
chr6_+_132552693 0.12 ENST00000275200.1
TAAR8
trace amine associated receptor 8
chr19_-_11346259 0.12 ENST00000590788.1
ENST00000354882.10
ENST00000586590.5
ENST00000589555.5
ENST00000586956.5
ENST00000593256.6
ENST00000447337.5
ENST00000591677.5
ENST00000586701.1
ENST00000589655.1
TMEM205
RAB3D
transmembrane protein 205
RAB3D, member RAS oncogene family
chr17_-_48613468 0.12 ENST00000498634.2
HOXB8
homeobox B8
chr1_-_68232539 0.12 ENST00000370976.7
ENST00000354777.6
WLS
Wnt ligand secretion mediator
chr19_+_49513353 0.12 ENST00000596975.5
FCGRT
Fc fragment of IgG receptor and transporter
chrX_+_37780049 0.12 ENST00000378588.5
CYBB
cytochrome b-245 beta chain
chr16_-_67483541 0.11 ENST00000290953.3
AGRP
agouti related neuropeptide
chr16_-_71577082 0.11 ENST00000355962.5
TAT
tyrosine aminotransferase
chr1_+_15341744 0.11 ENST00000444385.5
FHAD1
forkhead associated phosphopeptide binding domain 1
chr7_+_107583919 0.11 ENST00000491150.5
BCAP29
B cell receptor associated protein 29
chr5_-_175961324 0.11 ENST00000432305.6
ENST00000505969.1
THOC3
THO complex 3
chr2_-_208129824 0.11 ENST00000282141.4
CRYGC
crystallin gamma C
chr7_-_111392915 0.11 ENST00000450877.5
IMMP2L
inner mitochondrial membrane peptidase subunit 2
chr17_-_9791586 0.11 ENST00000571134.2
DHRS7C
dehydrogenase/reductase 7C
chr14_-_21098848 0.10 ENST00000556174.5
ENST00000554478.5
ENST00000553980.1
ENST00000421093.6
ZNF219
zinc finger protein 219
chr9_-_92536031 0.10 ENST00000344604.9
ENST00000375540.5
ECM2
extracellular matrix protein 2
chr13_-_52406160 0.10 ENST00000258613.5
THSD1
thrombospondin type 1 domain containing 1
chr4_-_142305935 0.10 ENST00000511838.5
INPP4B
inositol polyphosphate-4-phosphatase type II B
chr4_-_99435336 0.10 ENST00000437033.7
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr8_+_26293112 0.10 ENST00000523925.5
ENST00000315985.7
PPP2R2A
protein phosphatase 2 regulatory subunit Balpha
chr5_+_141192330 0.10 ENST00000239446.6
PCDHB10
protocadherin beta 10
chr12_-_81598332 0.10 ENST00000443686.7
PPFIA2
PTPRF interacting protein alpha 2
chr9_+_72577369 0.10 ENST00000651183.1
TMC1
transmembrane channel like 1
chr10_+_48684859 0.10 ENST00000360890.6
ENST00000325239.11
WDFY4
WDFY family member 4
chr12_+_12725897 0.09 ENST00000326765.10
APOLD1
apolipoprotein L domain containing 1
chr3_-_149576203 0.09 ENST00000472417.1
WWTR1
WW domain containing transcription regulator 1
chr15_+_51377247 0.09 ENST00000396399.6
GLDN
gliomedin
chr1_+_180632001 0.09 ENST00000367590.9
ENST00000367589.3
XPR1
xenotropic and polytropic retrovirus receptor 1
chr2_+_162318884 0.09 ENST00000446271.5
ENST00000429691.6
GCA
grancalcin
chr2_+_176129680 0.09 ENST00000429017.2
ENST00000313173.6
HOXD8
homeobox D8
chr5_+_36151989 0.09 ENST00000274254.9
SKP2
S-phase kinase associated protein 2
chr12_+_133181409 0.09 ENST00000416488.5
ENST00000228289.9
ENST00000541211.6
ENST00000536435.7
ENST00000500625.7
ENST00000539248.6
ENST00000542711.6
ENST00000536899.6
ENST00000542986.6
ENST00000611984.4
ENST00000541975.2
ZNF268
zinc finger protein 268
chr6_+_42929127 0.09 ENST00000394142.7
CNPY3
canopy FGF signaling regulator 3
chr15_+_75336053 0.09 ENST00000564815.5
ENST00000338995.10
ENST00000267935.13
COMMD4
COMM domain containing 4
chr7_+_23299306 0.08 ENST00000466681.2
MALSU1
mitochondrial assembly of ribosomal large subunit 1
chr12_-_10802627 0.08 ENST00000240687.2
TAS2R7
taste 2 receptor member 7
chr9_+_34652167 0.08 ENST00000441545.7
ENST00000553620.5
IL11RA
interleukin 11 receptor subunit alpha
chr17_+_3197519 0.08 ENST00000381951.1
OR1A2
olfactory receptor family 1 subfamily A member 2
chr21_+_46635595 0.08 ENST00000451211.6
ENST00000458387.6
ENST00000397638.6
ENST00000291705.11
ENST00000397637.5
ENST00000334494.8
ENST00000397628.5
ENST00000355680.8
ENST00000440086.5
PRMT2
protein arginine methyltransferase 2
chr7_+_90709530 0.08 ENST00000406263.5
CDK14
cyclin dependent kinase 14
chr3_-_157160751 0.08 ENST00000461804.5
CCNL1
cyclin L1
chr17_+_46511511 0.08 ENST00000576629.5
LRRC37A2
leucine rich repeat containing 37 member A2
chr1_+_244051275 0.08 ENST00000358704.4
ZBTB18
zinc finger and BTB domain containing 18
chr15_+_75336078 0.08 ENST00000567377.5
ENST00000562789.5
ENST00000568301.1
COMMD4
COMM domain containing 4
chr5_-_9630351 0.08 ENST00000382492.4
TAS2R1
taste 2 receptor member 1
chr2_+_165294031 0.08 ENST00000283256.10
SCN2A
sodium voltage-gated channel alpha subunit 2
chr16_+_21233672 0.08 ENST00000311620.7
ANKS4B
ankyrin repeat and sterile alpha motif domain containing 4B
chr12_+_57610150 0.08 ENST00000333972.11
ARHGEF25
Rho guanine nucleotide exchange factor 25
chr12_-_89352395 0.08 ENST00000308385.6
DUSP6
dual specificity phosphatase 6
chr12_-_68225806 0.07 ENST00000229134.5
IL26
interleukin 26
chr12_-_91004965 0.07 ENST00000261172.8
EPYC
epiphycan
chr19_-_57974527 0.07 ENST00000314391.3
C19orf18
chromosome 19 open reading frame 18
chr15_-_23687290 0.07 ENST00000649030.2
NDN
necdin, MAGE family member
chr8_-_17895403 0.07 ENST00000381840.5
ENST00000398054.5
FGL1
fibrinogen like 1
chr1_-_151175966 0.07 ENST00000441701.1
ENST00000295314.9
TMOD4
tropomodulin 4
chr8_-_17895487 0.07 ENST00000427924.5
ENST00000381841.4
FGL1
fibrinogen like 1
chr16_+_86566821 0.07 ENST00000649859.1
FOXC2
forkhead box C2
chr1_+_67166448 0.07 ENST00000347310.10
IL23R
interleukin 23 receptor
chr18_-_24311495 0.07 ENST00000357041.8
OSBPL1A
oxysterol binding protein like 1A
chr12_+_20810698 0.07 ENST00000540853.5
ENST00000381545.8
SLCO1B3
solute carrier organic anion transporter family member 1B3
chr5_+_141392616 0.07 ENST00000398604.3
PCDHGA8
protocadherin gamma subfamily A, 8
chr5_+_36152077 0.06 ENST00000546211.6
ENST00000620197.5
ENST00000678270.1
ENST00000679015.1
ENST00000678580.1
ENST00000274255.11
ENST00000508514.5
SKP2
S-phase kinase associated protein 2
chrX_+_35919725 0.06 ENST00000297866.9
ENST00000378653.8
CFAP47
cilia and flagella associated protein 47
chr5_+_42548043 0.06 ENST00000618088.4
ENST00000612382.4
GHR
growth hormone receptor
chr1_+_24556087 0.06 ENST00000374392.3
NCMAP
non-compact myelin associated protein
chr12_+_53461015 0.06 ENST00000553064.6
ENST00000547859.2
PCBP2
poly(rC) binding protein 2
chr11_-_95232514 0.06 ENST00000634898.1
ENST00000542176.1
ENST00000278499.6
SESN3
sestrin 3
chr5_+_141135199 0.06 ENST00000231134.8
ENST00000623915.1
PCDHB5
protocadherin beta 5
chr1_+_158845798 0.06 ENST00000438394.1
MNDA
myeloid cell nuclear differentiation antigen
chr21_-_42395943 0.06 ENST00000398405.5
TMPRSS3
transmembrane serine protease 3
chr12_-_89352487 0.06 ENST00000548755.1
ENST00000279488.8
DUSP6
dual specificity phosphatase 6
chr12_+_59689337 0.06 ENST00000261187.8
SLC16A7
solute carrier family 16 member 7
chr10_-_29634964 0.06 ENST00000375398.6
ENST00000355867.8
SVIL
supervillin
chr11_-_82997394 0.06 ENST00000525117.5
ENST00000532548.5
RAB30
RAB30, member RAS oncogene family
chr19_+_7030578 0.06 ENST00000329753.5
MBD3L5
methyl-CpG binding domain protein 3 like 5
chr19_+_55769118 0.06 ENST00000341750.5
RFPL4AL1
ret finger protein like 4A like 1
chr12_-_9999176 0.06 ENST00000298527.10
ENST00000348658.4
CLEC1B
C-type lectin domain family 1 member B
chr3_+_69936629 0.06 ENST00000394348.2
ENST00000531774.1
MITF
melanocyte inducing transcription factor
chr3_-_197573323 0.06 ENST00000358186.6
ENST00000431056.5
BDH1
3-hydroxybutyrate dehydrogenase 1
chr19_-_6393205 0.05 ENST00000595047.5
GTF2F1
general transcription factor IIF subunit 1
chr12_-_124567464 0.05 ENST00000458234.5
NCOR2
nuclear receptor corepressor 2
chr19_+_13731744 0.05 ENST00000586600.5
CCDC130
coiled-coil domain containing 130
chr12_-_118190510 0.05 ENST00000540561.5
ENST00000537952.1
ENST00000537822.1
TAOK3
TAO kinase 3
chr6_+_44219595 0.05 ENST00000393844.7
ENST00000652680.1
ENST00000643028.2
ENST00000371713.6
SLC29A1
solute carrier family 29 member 1 (Augustine blood group)
chr7_+_136868622 0.05 ENST00000680005.1
ENST00000445907.6
CHRM2
cholinergic receptor muscarinic 2
chr15_+_45252228 0.05 ENST00000560438.5
ENST00000347644.8
SLC28A2
solute carrier family 28 member 2
chr7_+_90709231 0.05 ENST00000446790.5
ENST00000265741.7
CDK14
cyclin dependent kinase 14
chr15_-_65115185 0.05 ENST00000559089.6
UBAP1L
ubiquitin associated protein 1 like
chr6_+_44219527 0.05 ENST00000651428.1
SLC29A1
solute carrier family 29 member 1 (Augustine blood group)
chr10_-_103351074 0.05 ENST00000337211.8
PCGF6
polycomb group ring finger 6
chr3_+_138621225 0.05 ENST00000479848.1
FAIM
Fas apoptotic inhibitory molecule
chr19_-_11346196 0.05 ENST00000586218.5
TMEM205
transmembrane protein 205
chr7_-_93890744 0.05 ENST00000650573.1
ENST00000222543.11
ENST00000649913.1
ENST00000647793.1
TFPI2
tissue factor pathway inhibitor 2
chr6_+_31927486 0.05 ENST00000442278.6
C2
complement C2
chr10_-_103351133 0.05 ENST00000369847.4
PCGF6
polycomb group ring finger 6
chr12_-_10807286 0.04 ENST00000240615.3
TAS2R8
taste 2 receptor member 8
chr19_-_51417581 0.04 ENST00000442846.7
ENST00000530476.1
SIGLEC10
sialic acid binding Ig like lectin 10
chr1_-_248277976 0.04 ENST00000641220.1
OR2T33
olfactory receptor family 2 subfamily T member 33
chr1_+_151766655 0.04 ENST00000400999.7
OAZ3
ornithine decarboxylase antizyme 3
chr5_+_141382702 0.04 ENST00000617050.1
ENST00000518325.2
PCDHGA7
protocadherin gamma subfamily A, 7
chr13_-_94479671 0.04 ENST00000377028.10
ENST00000446125.1
DCT
dopachrome tautomerase
chr5_+_90640718 0.04 ENST00000640403.1
ADGRV1
adhesion G protein-coupled receptor V1
chr7_+_142384328 0.04 ENST00000390361.3
TRBV7-3
T cell receptor beta variable 7-3
chr16_+_51553436 0.04 ENST00000565308.2
HNRNPA1P48
heterogeneous nuclear ribonucleoprotein A1 pseudogene 48
chr15_+_48191648 0.04 ENST00000646012.1
ENST00000561127.5
ENST00000647546.1
ENST00000559641.5
ENST00000417307.3
SLC12A1
CTXN2
solute carrier family 12 member 1
cortexin 2
chr15_-_37101205 0.04 ENST00000338564.9
ENST00000558313.5
ENST00000340545.9
MEIS2
Meis homeobox 2
chr17_-_10373002 0.04 ENST00000252172.9
ENST00000418404.8
MYH13
myosin heavy chain 13
chr5_-_135399863 0.04 ENST00000510038.1
ENST00000304332.8
MACROH2A1
macroH2A.1 histone
chr17_+_76467597 0.04 ENST00000392492.8
AANAT
aralkylamine N-acetyltransferase

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.8 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.4 1.2 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
0.2 1.7 GO:0097338 response to clozapine(GO:0097338)
0.2 0.5 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.1 0.4 GO:0006393 termination of mitochondrial transcription(GO:0006393)
0.1 0.3 GO:0070124 mitochondrial translational initiation(GO:0070124)
0.1 0.2 GO:0071284 copper ion export(GO:0060003) cellular response to lead ion(GO:0071284)
0.1 0.3 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.1 0.4 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.1 0.2 GO:0060738 epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738)
0.1 0.2 GO:0010645 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
0.1 0.2 GO:0072019 proximal convoluted tubule development(GO:0072019) metanephric proximal convoluted tubule development(GO:0072229)
0.0 0.3 GO:0042421 norepinephrine biosynthetic process(GO:0042421)
0.0 0.1 GO:0050928 negative regulation of positive chemotaxis(GO:0050928)
0.0 0.2 GO:0042710 biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229)
0.0 0.1 GO:1904432 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590) regulation of T cell antigen processing and presentation(GO:0002625) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440) response to iron ion starvation(GO:1990641)
0.0 0.2 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.0 0.1 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.0 0.1 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.0 0.4 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.1 GO:0061300 cerebellum vasculature development(GO:0061300)
0.0 0.1 GO:0045897 positive regulation of transcription during mitosis(GO:0045897)
0.0 0.5 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.1 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 0.4 GO:1902894 negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.0 0.2 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.0 0.5 GO:0006450 regulation of translational fidelity(GO:0006450)
0.0 0.1 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.0 0.7 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.2 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.0 0.5 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.1 GO:0035470 positive regulation of vascular wound healing(GO:0035470)
0.0 0.1 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.0 0.2 GO:0009449 glutamate biosynthetic process(GO:0006537) gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.0 0.1 GO:0015862 uridine transport(GO:0015862)
0.0 0.1 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.1 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.0 0.1 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 0.1 GO:0038155 interleukin-23-mediated signaling pathway(GO:0038155)
0.0 0.9 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.0 0.1 GO:0032290 peripheral nervous system myelin formation(GO:0032290)
0.0 0.6 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.0 GO:0015847 putrescine transport(GO:0015847)
0.0 0.1 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.1 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.0 0.0 GO:0030186 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0 0.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.1 GO:2000389 regulation of neutrophil extravasation(GO:2000389)
0.0 0.1 GO:1904970 brush border assembly(GO:1904970)
0.0 0.0 GO:0006570 tyrosine metabolic process(GO:0006570)
0.0 0.1 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.0 GO:0034414 tRNA 3'-trailer cleavage, endonucleolytic(GO:0034414) tRNA 3'-trailer cleavage(GO:0042779) mitochondrial tRNA 3'-end processing(GO:1990180)
0.0 0.2 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.2 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.0 GO:1903259 exon-exon junction complex disassembly(GO:1903259)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.8 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.1 1.7 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.8 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.3 GO:0042584 chromaffin granule membrane(GO:0042584)
0.0 0.1 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.1 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.3 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.2 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.1 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.0 0.1 GO:1990357 terminal web(GO:1990357)
0.0 0.2 GO:0032389 MutLalpha complex(GO:0032389)
0.0 0.1 GO:0070195 growth hormone receptor complex(GO:0070195)
0.0 0.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.1 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.0 0.4 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.2 GO:0005577 fibrinogen complex(GO:0005577)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.8 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.1 1.7 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 0.4 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.1 0.5 GO:0001594 trace-amine receptor activity(GO:0001594)
0.1 0.3 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.1 0.2 GO:0004008 copper-exporting ATPase activity(GO:0004008) phosphoglycerate kinase activity(GO:0004618) copper-transporting ATPase activity(GO:0043682)
0.1 0.5 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.1 0.3 GO:0052828 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.0 0.3 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 0.4 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.2 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.2 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.0 0.1 GO:0080130 L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.0 0.1 GO:0070052 collagen V binding(GO:0070052)
0.0 0.1 GO:0019770 IgG receptor activity(GO:0019770)
0.0 0.1 GO:0033142 progesterone receptor binding(GO:0033142)
0.0 0.2 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.0 0.1 GO:1990763 arrestin family protein binding(GO:1990763)
0.0 0.4 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.0 0.2 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.0 0.1 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 0.1 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.0 0.3 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.1 GO:0042019 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.0 0.3 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.4 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.3 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.5 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.0 GO:0015489 polyamine transmembrane transporter activity(GO:0015203) putrescine transmembrane transporter activity(GO:0015489)
0.0 1.1 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.7 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.0 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.0 0.1 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.0 0.1 GO:0005415 nucleoside:sodium symporter activity(GO:0005415)
0.0 0.3 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.0 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.0 0.1 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.3 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.1 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.0 GO:0042781 3'-tRNA processing endoribonuclease activity(GO:0042781)
0.0 0.2 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.1 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.0 GO:1902271 D3 vitamins binding(GO:1902271)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.7 PID IL3 PATHWAY IL3-mediated signaling events
0.0 1.2 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 1.2 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 1.4 PID TGFBR PATHWAY TGF-beta receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.7 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.5 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.4 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.2 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.3 REACTOME CA DEPENDENT EVENTS Genes involved in Ca-dependent events
0.0 0.3 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.4 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.2 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation