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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for PTF1A

Z-value: 0.77

Motif logo

Transcription factors associated with PTF1A

Gene Symbol Gene ID Gene Info
ENSG00000168267.7 PTF1A

Activity profile of PTF1A motif

Sorted Z-values of PTF1A motif

Network of associatons between targets according to the STRING database.

First level regulatory network of PTF1A

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr11_+_71527267 3.44 ENST00000398536.6
keratin associated protein 5-7
chr20_+_43916142 2.11 ENST00000423191.6
ENST00000372999.5
TOX high mobility group box family member 2
chr21_-_44592505 2.01 ENST00000400368.1
keratin associated protein 10-6
chr4_-_122922442 1.71 ENST00000510735.1
ENST00000304430.10
nudix hydrolase 6
chr7_+_150991087 1.52 ENST00000461406.5
nitric oxide synthase 3
chr13_+_31945826 1.35 ENST00000647500.1
FRY microtubule binding protein
chr11_-_1608463 1.13 ENST00000399685.1
keratin associated protein 5-3
chr4_-_88823306 0.91 ENST00000395002.6
family with sequence similarity 13 member A
chr1_+_230979064 0.88 ENST00000366658.6
ENST00000310256.7
ENST00000450711.5
ENST00000435927.5
ARV1 homolog, fatty acid homeostasis modulator
chr19_-_10380454 0.88 ENST00000530829.1
ENST00000529370.5
tyrosine kinase 2
chr4_+_40196907 0.87 ENST00000622175.4
ENST00000619474.4
ENST00000615083.4
ENST00000610353.4
ENST00000614836.1
ras homolog family member H
chr4_+_155666827 0.82 ENST00000511507.5
ENST00000506455.6
guanylate cyclase 1 soluble subunit alpha 1
chr17_-_75896911 0.81 ENST00000540128.1
ENST00000269383.8
tripartite motif containing 65
chr4_+_40197023 0.77 ENST00000381799.10
ras homolog family member H
chr11_+_64340191 0.74 ENST00000356786.10
coiled-coil domain containing 88B
chr1_-_230978796 0.72 ENST00000522821.5
ENST00000366662.8
ENST00000366661.9
ENST00000522399.1
tetratricopeptide repeat domain 13
chr2_+_201257980 0.65 ENST00000447616.5
ENST00000358485.8
ENST00000392266.7
caspase 8
chr3_+_126524319 0.63 ENST00000615522.1
carbohydrate sulfotransferase 13
chr17_+_69502397 0.62 ENST00000613873.4
ENST00000589647.5
mitogen-activated protein kinase kinase 6
chr1_+_26529745 0.59 ENST00000374168.7
ENST00000374166.8
ribosomal protein S6 kinase A1
chr19_-_46023046 0.57 ENST00000008938.5
peptidoglycan recognition protein 1
chr8_-_109648825 0.56 ENST00000533895.5
ENST00000446070.6
ENST00000528331.5
ENST00000526302.5
ENST00000408908.6
ENST00000433638.1
ENST00000524720.5
syntabulin
chr4_-_143700675 0.55 ENST00000329798.5
FRAS1 related extracellular matrix 3
chr4_-_82798735 0.54 ENST00000273908.4
ENST00000319540.9
stearoyl-CoA desaturase 5
chr10_+_48684859 0.53 ENST00000360890.6
ENST00000325239.11
WDFY family member 4
chr6_-_149923077 0.53 ENST00000367360.7
ENST00000479265.1
retinoic acid early transcript 1G
chr1_-_9069797 0.51 ENST00000473209.1
solute carrier family 2 member 5
chr12_+_112906777 0.50 ENST00000452357.7
ENST00000445409.7
2'-5'-oligoadenylate synthetase 1
chr11_+_6863057 0.49 ENST00000641461.1
olfactory receptor family 10 subfamily A member 2
chr11_-_111923722 0.49 ENST00000527950.5
crystallin alpha B
chr12_+_93571664 0.47 ENST00000622746.4
ENST00000548537.1
suppressor of cytokine signaling 2
chr13_-_79405784 0.46 ENST00000267229.11
RNA binding motif protein 26
chr19_+_18340581 0.46 ENST00000604499.6
ENST00000269919.11
ENST00000595066.5
ENST00000252813.5
pyroglutamyl-peptidase I
chr12_+_112906949 0.46 ENST00000679971.1
ENST00000675868.2
ENST00000550883.2
ENST00000553152.2
ENST00000202917.10
ENST00000679467.1
ENST00000680659.1
ENST00000540589.3
ENST00000552526.2
ENST00000681228.1
ENST00000680934.1
ENST00000681700.1
ENST00000679987.1
2'-5'-oligoadenylate synthetase 1
chr1_+_150508099 0.45 ENST00000346569.6
ENST00000369047.9
extracellular matrix protein 1
chr1_+_150508074 0.44 ENST00000369049.8
extracellular matrix protein 1
chr19_-_39204254 0.43 ENST00000318438.7
syncollin
chr2_-_240682879 0.42 ENST00000407834.4
ENST00000621682.4
aquaporin 12B
chr3_-_169869833 0.42 ENST00000523069.1
ENST00000264676.9
ENST00000316428.10
leucine rich repeat containing 31
chr6_-_2962097 0.41 ENST00000380524.5
serpin family B member 6
chr9_-_113298865 0.41 ENST00000416588.2
ring finger protein 183
chr4_+_81030700 0.40 ENST00000282701.4
bone morphogenetic protein 3
chr1_-_75611109 0.40 ENST00000370859.7
solute carrier family 44 member 5
chr12_+_112907006 0.40 ENST00000680455.1
ENST00000551241.6
ENST00000550689.2
ENST00000679841.1
ENST00000679494.1
ENST00000553185.2
2'-5'-oligoadenylate synthetase 1
chr10_+_122980392 0.39 ENST00000406217.8
phosphoseryl-tRNA kinase
chr20_+_18145083 0.39 ENST00000489634.2
lysine acetyltransferase 14
chr12_+_50057548 0.39 ENST00000228468.8
ENST00000447966.7
acid sensing ion channel subunit 1
chr2_+_240691851 0.38 ENST00000429564.1
ENST00000337801.9
aquaporin 12A
chr5_-_163460067 0.38 ENST00000302764.9
NudC domain containing 2
chr5_-_75717368 0.38 ENST00000514838.6
ENST00000506164.5
ENST00000502826.5
ENST00000428202.7
ENST00000503835.5
POC5 centriolar protein
chr12_+_93571832 0.38 ENST00000549887.1
suppressor of cytokine signaling 2
chr2_+_171999937 0.38 ENST00000315796.5
methionyl aminopeptidase type 1D, mitochondrial
chr15_+_40807590 0.38 ENST00000299173.14
ENST00000566407.5
zinc finger FYVE-type containing 19
chr5_-_163460048 0.37 ENST00000517501.1
NudC domain containing 2
chr9_+_122519141 0.35 ENST00000340750.1
olfactory receptor family 1 subfamily J member 4
chr1_-_45491150 0.35 ENST00000372086.4
testis associated actin remodelling kinase 2
chr19_-_9219589 0.35 ENST00000641244.1
ENST00000641669.1
olfactory receptor family 7 subfamily D member 4
chr12_-_48004467 0.33 ENST00000380518.8
collagen type II alpha 1 chain
chr19_+_6464491 0.32 ENST00000308243.7
crumbs cell polarity complex component 3
chr10_-_27243019 0.32 ENST00000679293.1
acyl-CoA binding domain containing 5
chr14_-_106025628 0.32 ENST00000631943.1
immunoglobulin heavy variable 7-4-1
chr3_+_48990219 0.30 ENST00000383729.9
prolyl 4-hydroxylase, transmembrane
chr1_-_75611083 0.29 ENST00000370855.5
solute carrier family 44 member 5
chr8_-_98294195 0.29 ENST00000430223.7
NIPA like domain containing 2
chr18_-_55510753 0.28 ENST00000543082.5
transcription factor 4
chr20_+_56248732 0.28 ENST00000243911.2
melanocortin 3 receptor
chr14_+_76826372 0.28 ENST00000393774.7
ENST00000555189.1
leucine rich repeat containing 74A
chr22_-_17159220 0.28 ENST00000399852.3
ENST00000336737.8
haloacid dehalogenase like hydrolase domain containing 5
chr17_-_3557798 0.27 ENST00000301365.8
ENST00000572519.1
ENST00000576742.6
transient receptor potential cation channel subfamily V member 3
chr1_-_113905020 0.27 ENST00000432415.5
ENST00000369571.2
ENST00000256658.8
ENST00000369564.5
adaptor related protein complex 4 subunit beta 1
chr14_-_34630109 0.27 ENST00000396526.7
sorting nexin 6
chr3_+_126524131 0.26 ENST00000319340.7
carbohydrate sulfotransferase 13
chr11_-_1622093 0.25 ENST00000616115.1
ENST00000399682.1
keratin associated protein 5-4
chr4_-_88823165 0.25 ENST00000508369.5
family with sequence similarity 13 member A
chr1_-_9069608 0.24 ENST00000377424.9
solute carrier family 2 member 5
chr6_-_41747390 0.24 ENST00000356667.8
ENST00000373025.7
ENST00000425343.6
progastricsin
chr8_-_98294339 0.24 ENST00000341166.3
NIPA like domain containing 2
chr7_-_152676130 0.23 ENST00000359321.2
X-ray repair cross complementing 2
chr16_-_1954682 0.23 ENST00000268661.8
ribosomal protein L3 like
chr3_+_57060658 0.23 ENST00000334325.2
spermatogenesis associated 12
chr13_-_20525796 0.23 ENST00000298248.12
ENST00000382812.5
ENST00000644593.1
ENST00000643750.1
crystallin lambda 1
chr8_-_38269116 0.23 ENST00000529359.5
phospholipid phosphatase 5
chr3_+_48989876 0.23 ENST00000343546.8
prolyl 4-hydroxylase, transmembrane
chr6_+_57317602 0.23 ENST00000274891.10
ENST00000671770.1
ENST00000672107.1
ENST00000615550.5
DNA primase subunit 2
chr17_-_35986649 0.22 ENST00000622526.1
ENST00000620991.1
ENST00000618404.5
C-C motif chemokine ligand 14
chr2_-_135530561 0.22 ENST00000536680.5
ENST00000401392.5
zinc finger RANBP2-type containing 3
chr8_+_11494367 0.22 ENST00000259089.9
ENST00000529894.1
BLK proto-oncogene, Src family tyrosine kinase
chr14_-_34630124 0.22 ENST00000362031.10
ENST00000557265.6
ENST00000652385.1
sorting nexin 6
chr16_+_46884675 0.22 ENST00000562132.5
ENST00000440783.2
glutamic--pyruvic transaminase 2
chr5_+_56909586 0.21 ENST00000285947.5
SET domain containing 9
chr1_+_12125892 0.21 ENST00000413146.6
TNF receptor superfamily member 8
chr20_-_45631235 0.20 ENST00000326000.2
WAP four-disulfide core domain 9
chr20_+_46008900 0.20 ENST00000372330.3
matrix metallopeptidase 9
chrX_-_44542833 0.20 ENST00000378045.5
FUN14 domain containing 1
chr4_-_88823214 0.19 ENST00000513837.5
ENST00000503556.5
family with sequence similarity 13 member A
chr12_+_75391078 0.19 ENST00000550916.6
ENST00000378692.7
ENST00000320460.8
ENST00000547164.1
GLIPR1 like 2
chr13_-_31162341 0.19 ENST00000445273.6
ENST00000630972.2
heat shock protein family H (Hsp110) member 1
chr1_-_113904789 0.18 ENST00000369569.6
ENST00000369567.5
adaptor related protein complex 4 subunit beta 1
chr7_+_142111739 0.18 ENST00000550469.6
ENST00000477922.3
maltase-glucoamylase 2 (putative)
chr7_-_5513738 0.18 ENST00000453700.7
ENST00000382368.8
F-box and leucine rich repeat protein 18
chr1_+_200739542 0.18 ENST00000358823.6
calmodulin regulated spectrin associated protein family member 2
chr15_+_51341648 0.18 ENST00000335449.11
ENST00000560215.5
gliomedin
chr20_+_31368594 0.17 ENST00000253381.3
defensin beta 118
chr12_-_120446372 0.17 ENST00000546954.2
TP53 regulated inhibitor of apoptosis 1
chr15_+_79311137 0.17 ENST00000424155.6
ENST00000536821.5
transmembrane p24 trafficking protein 3
chr16_+_89630263 0.17 ENST00000261615.5
dipeptidase 1
chr16_+_71358713 0.17 ENST00000349553.9
ENST00000302628.9
ENST00000562305.5
calbindin 2
chr19_-_5867741 0.16 ENST00000252675.6
fucosyltransferase 5
chr14_-_49688201 0.16 ENST00000553805.2
ENST00000554396.5
ENST00000216367.10
DNA polymerase epsilon 2, accessory subunit
chr19_+_11559429 0.16 ENST00000585493.5
zinc finger protein 627
chr8_-_144416481 0.15 ENST00000276833.9
solute carrier family 39 member 4
chr3_+_35679690 0.15 ENST00000413378.5
ENST00000417925.5
cAMP regulated phosphoprotein 21
chr12_-_21941402 0.15 ENST00000326684.8
ENST00000682068.1
ENST00000621589.2
ENST00000261200.9
ENST00000683676.1
ATP binding cassette subfamily C member 9
chr7_+_142760398 0.15 ENST00000632998.1
serine protease 2
chr13_-_31161890 0.15 ENST00000320027.10
heat shock protein family H (Hsp110) member 1
chr12_+_53295506 0.15 ENST00000549759.2
ENST00000628881.2
ENST00000351500.7
ENST00000550846.5
ENST00000334478.9
ENST00000547130.6
ENST00000552742.6
prefoldin subunit 5
chr4_+_155666963 0.14 ENST00000455639.6
guanylate cyclase 1 soluble subunit alpha 1
chr4_+_155666718 0.14 ENST00000621234.4
ENST00000511108.5
guanylate cyclase 1 soluble subunit alpha 1
chrX_+_155071473 0.13 ENST00000369459.6
ENST00000369462.5
ENST00000330045.12
ENST00000411985.5
ENST00000399042.4
ENST00000620502.4
ENST00000630295.1
BRCA1/BRCA2-containing complex subunit 3
chr6_-_24877262 0.13 ENST00000378023.8
ENST00000540914.5
RHO family interacting cell polarization regulator 2
chr2_+_27211992 0.12 ENST00000380171.8
ENST00000611786.4
all-trans retinoic acid induced differentiation factor
chr3_+_89107613 0.12 ENST00000336596.7
EPH receptor A3
chr17_+_38297023 0.12 ENST00000619548.1
ENST00000613675.5
mitochondrial ribosomal protein L45
chr1_+_100038087 0.12 ENST00000370152.8
major facilitator superfamily domain containing 14A
chr2_+_119429889 0.11 ENST00000409826.1
ENST00000417645.1
transmembrane protein 37
chr19_+_9178979 0.11 ENST00000642043.1
ENST00000641288.2
olfactory receptor family 7 subfamily D member 2
chr7_-_88795732 0.11 ENST00000297203.3
testis expressed 47
chr10_+_75111595 0.11 ENST00000671800.1
ENST00000542569.6
ENST00000372687.4
sterile alpha motif domain containing 8
chr14_-_76826229 0.11 ENST00000557497.1
angel homolog 1
chr7_+_30284574 0.10 ENST00000323037.5
zinc and ring finger 2
chr5_-_118988504 0.10 ENST00000515439.7
ENST00000510708.6
DTW domain containing 2
chr2_+_218880844 0.10 ENST00000258411.8
Wnt family member 10A
chr22_+_24603147 0.10 ENST00000412658.5
ENST00000445029.5
ENST00000400382.6
ENST00000419133.5
ENST00000438643.6
ENST00000452551.5
ENST00000412898.5
ENST00000400380.5
ENST00000455483.5
ENST00000430289.5
gamma-glutamyltransferase 1
chr5_+_141213919 0.09 ENST00000341948.6
protocadherin beta 13
chr4_+_20700436 0.09 ENST00000444671.6
ENST00000510700.5
ENST00000506745.5
ENST00000514663.5
ENST00000509469.5
ENST00000515339.5
ENST00000513861.5
ENST00000502374.5
ENST00000503585.6
ENST00000511160.5
ENST00000504630.5
ENST00000513590.5
ENST00000514292.5
ENST00000502938.5
ENST00000509625.1
ENST00000505160.1
ENST00000507634.5
ENST00000513459.5
ENST00000511089.1
parkin coregulated like
chr10_-_73096974 0.09 ENST00000440381.5
ENST00000263556.3
prolyl 4-hydroxylase subunit alpha 1
chr3_+_35639515 0.09 ENST00000684406.1
cAMP regulated phosphoprotein 21
chr10_+_122980448 0.08 ENST00000405485.2
phosphoseryl-tRNA kinase
chr2_+_85695368 0.08 ENST00000526018.1
granulysin
chr20_-_3663399 0.08 ENST00000290417.7
ENST00000319242.8
GDNF family receptor alpha 4
chr20_-_50115935 0.08 ENST00000340309.7
ENST00000415862.6
ENST00000371677.7
ubiquitin conjugating enzyme E2 V1
chr3_-_122993232 0.08 ENST00000650207.1
ENST00000616742.4
ENST00000393583.6
semaphorin 5B
chr12_+_112013418 0.08 ENST00000261735.4
ENST00000552052.1
endoplasmic reticulum protein 29
chr20_-_63216102 0.07 ENST00000370339.8
ENST00000370334.4
YTH N6-methyladenosine RNA binding protein 1
chr7_+_142750657 0.07 ENST00000492062.1
serine protease 1
chr12_+_112013348 0.07 ENST00000455836.1
endoplasmic reticulum protein 29
chr12_+_56996151 0.06 ENST00000556850.1
G protein-coupled receptor 182
chr1_-_9069572 0.06 ENST00000377414.7
solute carrier family 2 member 5
chr12_+_1820255 0.06 ENST00000543818.5
leucine rich repeats and transmembrane domains 2
chr14_-_58427114 0.06 ENST00000556007.6
translocase of inner mitochondrial membrane 9
chr3_-_155293665 0.06 ENST00000489090.2
small transmembrane regulator of ion transport 1
chrX_+_155881306 0.06 ENST00000286448.12
ENST00000262640.11
ENST00000460621.6
vesicle associated membrane protein 7
chr2_+_183078736 0.05 ENST00000354221.5
dual specificity phosphatase 19
chr1_+_39738866 0.05 ENST00000324379.10
ENST00000356511.6
ENST00000497370.5
ENST00000470213.5
ENST00000372835.9
ENST00000372830.5
peptidylprolyl isomerase E
chr9_-_101383558 0.05 ENST00000674556.1
bile acid-CoA:amino acid N-acyltransferase
chr8_-_144416819 0.05 ENST00000526658.1
ENST00000301305.8
solute carrier family 39 member 4
chr14_-_106470788 0.05 ENST00000434710.1
immunoglobulin heavy variable 3-43
chr7_+_142749465 0.05 ENST00000486171.5
ENST00000619214.4
ENST00000311737.12
serine protease 1
chr3_+_40477107 0.04 ENST00000314686.9
ENST00000447116.6
ENST00000429348.6
ENST00000432264.4
ENST00000456778.5
zinc finger protein 619
chr10_-_73096850 0.04 ENST00000307116.6
ENST00000373008.6
ENST00000394890.7
prolyl 4-hydroxylase subunit alpha 1
chr12_+_1820558 0.04 ENST00000299194.6
leucine rich repeats and transmembrane domains 2
chr1_-_204685700 0.04 ENST00000367177.4
leucine rich repeat neuronal 2
chr2_-_70768175 0.04 ENST00000355733.7
ENST00000447731.6
ENST00000430656.5
ENST00000264436.9
ENST00000413157.6
adducin 2
chr17_+_55264952 0.04 ENST00000226067.10
HLF transcription factor, PAR bZIP family member
chr8_-_134712962 0.03 ENST00000523399.5
ENST00000377838.8
zinc finger and AT-hook domain containing
chr2_+_97646034 0.03 ENST00000258424.3
cytochrome c oxidase subunit 5B
chr1_+_9997220 0.03 ENST00000294435.8
retinol binding protein 7
chr17_+_29568591 0.03 ENST00000581411.6
ENST00000301057.8
tumor protein p53 inducible protein 13
chr14_-_58427134 0.03 ENST00000555930.6
translocase of inner mitochondrial membrane 9
chr12_+_51238724 0.03 ENST00000449723.7
ENST00000549555.5
ENST00000439799.6
ENST00000412716.8
ENST00000425012.6
DAZ associated protein 2
chr1_-_158330957 0.03 ENST00000451207.5
CD1b molecule
chr2_-_196068812 0.02 ENST00000410072.5
ENST00000312428.11
dynein axonemal heavy chain 7
chr3_-_12841527 0.02 ENST00000396953.6
ENST00000457131.1
ENST00000435983.5
ENST00000273223.10
ENST00000429711.7
ENST00000396957.5
ribosomal protein L32
chr11_+_8683201 0.02 ENST00000526562.5
ENST00000525981.1
ribosomal protein L27a
chr14_-_58427158 0.02 ENST00000555097.1
ENST00000556367.6
ENST00000555404.5
translocase of inner mitochondrial membrane 9
chr3_-_196211386 0.01 ENST00000296326.8
zinc finger DHHC-type palmitoyltransferase 19
chr14_-_106875069 0.01 ENST00000390639.2
immunoglobulin heavy variable 7-81 (non-functional)
chr16_+_2752622 0.01 ENST00000576924.5
ENST00000575009.5
ENST00000301740.13
ENST00000630499.2
ENST00000576415.5
ENST00000571378.5
serine/arginine repetitive matrix 2
chr3_-_52834901 0.01 ENST00000486659.5
musculoskeletal, embryonic nuclear protein 1
chr9_-_135961310 0.01 ENST00000371756.4
UBA domain containing 1
chr17_+_42844573 0.01 ENST00000253799.8
ENST00000452774.2
amine oxidase copper containing 2
chr22_+_24270776 0.01 ENST00000437398.5
ENST00000421374.5
ENST00000314328.14
ENST00000651059.1
ENST00000541492.1
sperm antigen with calponin homology and coiled-coil domains 1 like
chr11_-_624924 0.01 ENST00000358353.8
ENST00000397542.7
ENST00000526077.5
ENST00000534311.1
ENST00000531088.5
cadherin related family member 5
chr11_+_57181945 0.00 ENST00000497933.3
leucine rich repeat containing 55

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0014740 negative regulation of muscle hyperplasia(GO:0014740)
0.3 1.4 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.2 0.6 GO:0072709 cellular response to sorbitol(GO:0072709)
0.2 0.6 GO:0032827 natural killer cell differentiation involved in immune response(GO:0002325) negative regulation of natural killer cell differentiation(GO:0032824) regulation of natural killer cell differentiation involved in immune response(GO:0032826) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827) positive regulation of cytolysis in other organism(GO:0051714)
0.2 0.6 GO:0039513 modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
0.1 0.8 GO:0032445 fructose transport(GO:0015755) fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.1 0.9 GO:0032377 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.1 0.5 GO:0097056 selenocysteinyl-tRNA(Sec) biosynthetic process(GO:0097056)
0.1 0.6 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.1 0.4 GO:0050915 sensory perception of sour taste(GO:0050915)
0.1 0.2 GO:0036292 DNA rewinding(GO:0036292)
0.1 0.2 GO:0045553 TRAIL biosynthetic process(GO:0045553) regulation of TRAIL biosynthetic process(GO:0045554) positive regulation of TRAIL biosynthetic process(GO:0045556)
0.1 0.5 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.1 0.4 GO:0044878 mitotic cytokinesis checkpoint(GO:0044878)
0.1 0.2 GO:0016999 antibiotic metabolic process(GO:0016999)
0.1 0.2 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.0 0.3 GO:1903751 regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
0.0 0.3 GO:0042636 negative regulation of hair cycle(GO:0042636)
0.0 0.2 GO:0042851 L-alanine metabolic process(GO:0042851) L-alanine catabolic process(GO:0042853)
0.0 0.5 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.7 GO:0015871 choline transport(GO:0015871)
0.0 0.1 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.0 0.2 GO:0002803 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antibacterial peptide production(GO:0002803)
0.0 0.2 GO:0006064 glucuronate catabolic process(GO:0006064) glucuronate catabolic process to xylulose 5-phosphate(GO:0019640) xylulose 5-phosphate metabolic process(GO:0051167) xylulose 5-phosphate biosynthetic process(GO:1901159)
0.0 0.8 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.1 GO:0043335 protein unfolding(GO:0043335)
0.0 0.3 GO:0030242 pexophagy(GO:0030242)
0.0 0.2 GO:2001268 negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
0.0 0.2 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 0.9 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.0 0.2 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 0.5 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.1 GO:0002818 intracellular defense response(GO:0002818)
0.0 0.1 GO:1903904 negative regulation of establishment of T cell polarity(GO:1903904) negative regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001107)
0.0 0.2 GO:0051673 membrane disruption in other organism(GO:0051673)
0.0 4.6 GO:0031424 keratinization(GO:0031424)
0.0 0.4 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 1.6 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 0.9 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.3 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.2 GO:0060174 limb bud formation(GO:0060174)
0.0 0.1 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.0 1.4 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.2 GO:2001140 regulation of phospholipid transport(GO:2001138) positive regulation of phospholipid transport(GO:2001140)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.1 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.2 GO:0042355 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 0.2 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.1 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 1.1 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.7 GO:0031122 cytoplasmic microtubule organization(GO:0031122)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0097013 phagocytic vesicle lumen(GO:0097013)
0.1 0.9 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.1 0.5 GO:0030905 retromer, tubulation complex(GO:0030905)
0.1 4.6 GO:0045095 keratin filament(GO:0045095)
0.0 0.9 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.1 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.0 0.6 GO:0097433 dense body(GO:0097433)
0.0 0.2 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.2 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.5 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.6 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.1 GO:0035370 UBC13-UEV1A complex(GO:0035370)
0.0 0.2 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 1.6 GO:0001772 immunological synapse(GO:0001772)
0.0 0.1 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.4 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.2 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.3 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.0 0.1 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.0 0.1 GO:0060171 stereocilium membrane(GO:0060171)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.5 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.1 0.6 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.1 0.8 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.1 0.5 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.1 0.9 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 1.7 GO:0005131 growth hormone receptor binding(GO:0005131)
0.1 0.9 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.1 0.6 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.1 0.3 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.1 1.4 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 0.4 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.1 0.7 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.1 0.2 GO:0047635 L-alanine:2-oxoglutarate aminotransferase activity(GO:0004021) alanine-oxo-acid transaminase activity(GO:0047635)
0.1 0.2 GO:0004339 glucan 1,4-alpha-glucosidase activity(GO:0004339)
0.1 1.6 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.1 0.5 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.0 0.2 GO:0003896 DNA primase activity(GO:0003896)
0.0 0.2 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.2 GO:0070573 metallodipeptidase activity(GO:0070573)
0.0 0.4 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.4 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.1 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.2 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0 0.2 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.5 GO:0034452 dynactin binding(GO:0034452)
0.0 0.3 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.1 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.0 0.5 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.2 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.6 GO:0008242 omega peptidase activity(GO:0008242)
0.0 0.9 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.8 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 1.6 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.5 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.0 0.0 GO:0052816 medium-chain acyl-CoA hydrolase activity(GO:0052815) long-chain acyl-CoA hydrolase activity(GO:0052816)
0.0 0.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.2 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 0.6 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.2 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.2 GO:0000150 recombinase activity(GO:0000150)
0.0 0.2 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.3 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.3 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.1 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0 0.1 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.0 0.2 GO:0008195 phosphatidate phosphatase activity(GO:0008195)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.6 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 1.5 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 0.6 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.6 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.8 PID IL2 1PATHWAY IL2-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.8 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.8 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.6 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.2 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.6 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.9 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.8 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.7 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.6 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 1.4 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.5 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix