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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for RAD21_SMC3

Z-value: 0.75

Motif logo

Transcription factors associated with RAD21_SMC3

Gene Symbol Gene ID Gene Info
ENSG00000164754.15 RAD21
ENSG00000108055.10 SMC3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SMC3hg38_v1_chr10_+_110567666_1105677650.174.1e-01Click!
RAD21hg38_v1_chr8_-_116874746_1168748280.086.9e-01Click!

Activity profile of RAD21_SMC3 motif

Sorted Z-values of RAD21_SMC3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of RAD21_SMC3

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr16_-_30021288 3.46 ENST00000574405.5
double C2 domain alpha
chr7_-_27180230 2.02 ENST00000396344.4
homeobox A10
chr12_+_82358496 1.93 ENST00000248306.8
ENST00000548200.5
methyltransferase like 25
chr8_+_142727186 1.77 ENST00000336138.4
thioesterase superfamily member 6
chr2_+_6917404 1.43 ENST00000320892.11
ring finger protein 144A
chr7_+_90154442 1.42 ENST00000297205.7
STEAP family member 1
chr1_+_37474572 1.36 ENST00000373087.7
zinc finger CCCH-type containing 12A
chr9_+_136665745 1.35 ENST00000371698.3
EGF like domain multiple 7
chr3_-_128493173 1.26 ENST00000498200.1
ENST00000341105.7
GATA binding protein 2
chr8_-_77000194 1.24 ENST00000522527.5
peroxisomal biogenesis factor 2
chr3_+_134795248 1.23 ENST00000398015.8
EPH receptor B1
chr12_-_120265719 1.21 ENST00000637617.2
ENST00000267257.11
ENST00000228307.11
ENST00000424649.6
paxillin
chr3_+_39809602 1.16 ENST00000302541.11
ENST00000396217.7
myosin VIIA and Rab interacting protein
chr22_+_19718390 1.15 ENST00000383045.7
ENST00000438754.6
septin 5
chr2_+_20667136 1.12 ENST00000272224.5
growth differentiation factor 7
chr2_+_69013170 1.11 ENST00000303714.9
ANTXR cell adhesion molecule 1
chr12_+_53046969 1.11 ENST00000379902.7
tensin 2
chr14_-_91060113 1.11 ENST00000536315.6
ribosomal protein S6 kinase A5
chr13_-_52450590 1.02 ENST00000378060.9
vacuolar protein sorting 36 homolog
chr12_+_50504970 0.99 ENST00000301180.10
disco interacting protein 2 homolog B
chr12_+_13044371 0.98 ENST00000197268.13
family with sequence similarity 234 member B
chr8_-_77000070 0.96 ENST00000357039.9
peroxisomal biogenesis factor 2
chr3_+_49171590 0.92 ENST00000332780.4
kelch domain containing 8B
chr5_+_54517706 0.90 ENST00000326277.5
ENST00000381410.5
ENST00000343017.11
sorting nexin 18
chr5_+_175872741 0.89 ENST00000502265.5
complexin 2
chr9_+_124853417 0.88 ENST00000613760.4
ENST00000618744.4
ENST00000373574.2
WD repeat domain 38
chr19_-_38256339 0.88 ENST00000591291.5
ENST00000301242.9
protein phosphatase 1 regulatory inhibitor subunit 14A
chr10_-_75235917 0.88 ENST00000469299.1
ENST00000372538.8
catechol-O-methyltransferase domain containing 1
chr12_-_56189459 0.86 ENST00000550164.6
SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2
chr7_-_100827504 0.86 ENST00000616502.4
ENST00000358173.8
EPH receptor B4
chr19_-_38256513 0.86 ENST00000347262.8
ENST00000591585.1
protein phosphatase 1 regulatory inhibitor subunit 14A
chr12_-_51269949 0.85 ENST00000603864.5
ENST00000605426.5
small cell adhesion glycoprotein
chr12_+_6924449 0.84 ENST00000356654.8
atrophin 1
chr1_+_212035717 0.83 ENST00000366991.5
denticleless E3 ubiquitin protein ligase homolog
chr3_+_49803212 0.79 ENST00000333323.6
inka box actin regulator 1
chr6_+_25279359 0.77 ENST00000329474.7
capping protein regulator and myosin 1 linker 1
chr8_-_73746830 0.76 ENST00000524300.6
ENST00000523558.5
ENST00000521210.5
ENST00000355780.9
ENST00000524104.5
ENST00000521736.5
ENST00000521447.5
ENST00000517542.5
ENST00000521451.5
ENST00000521419.5
ENST00000518502.5
staufen double-stranded RNA binding protein 2
chr14_+_22040576 0.76 ENST00000390448.3
T cell receptor alpha variable 20
chr1_+_92029971 0.76 ENST00000370383.5
epoxide hydrolase 4
chr15_+_65611336 0.76 ENST00000537259.5
solute carrier family 24 member 1
chr3_-_184017863 0.75 ENST00000427120.6
ENST00000334444.11
ENST00000392579.6
ENST00000382494.6
ENST00000265586.10
ENST00000446941.2
ATP binding cassette subfamily C member 5
chr19_+_47713412 0.74 ENST00000538399.1
ENST00000263277.8
EH domain containing 2
chr10_-_100009860 0.74 ENST00000324109.9
dynamin binding protein
chr3_+_20040437 0.74 ENST00000263754.5
lysine acetyltransferase 2B
chr3_+_134795277 0.71 ENST00000647596.1
EPH receptor B1
chr11_-_119340544 0.67 ENST00000530681.2
C1q and TNF related 5
chr11_+_925809 0.67 ENST00000332231.9
adaptor related protein complex 2 subunit alpha 2
chr19_+_10416773 0.66 ENST00000592685.5
phosphodiesterase 4A
chr6_+_136038195 0.65 ENST00000615259.4
phosphodiesterase 7B
chr17_+_45135640 0.65 ENST00000586346.5
ENST00000321854.13
ENST00000398322.7
ENST00000592162.5
ENST00000376955.8
acyl-CoA binding domain containing 4
chr15_-_44195210 0.65 ENST00000402883.5
ENST00000417257.6
FERM domain containing 5
chr17_+_63484840 0.65 ENST00000290863.10
ENST00000413513.7
angiotensin I converting enzyme
chr3_-_47475811 0.65 ENST00000265565.10
ENST00000428413.5
SREBF chaperone
chr12_-_51270175 0.64 ENST00000604188.1
ENST00000398453.7
small cell adhesion glycoprotein
chr8_-_100559702 0.64 ENST00000520311.5
ENST00000520552.5
ENST00000521345.1
ENST00000523000.5
ENST00000335659.7
ENST00000358990.3
ENST00000519597.5
ankyrin repeat domain 46
chr19_-_18941184 0.62 ENST00000594794.5
ENST00000392351.8
ENST00000596482.5
homer scaffold protein 3
chr16_+_29816084 0.62 ENST00000320330.8
PAXIP1 associated glutamate rich protein 1
chr6_+_34514853 0.61 ENST00000538621.2
protein kinase C and casein kinase substrate in neurons 1
chr11_-_118565992 0.60 ENST00000264020.6
intraflagellar transport 46
chr8_+_28622729 0.60 ENST00000523149.5
exostosin like glycosyltransferase 3
chr2_+_102473219 0.59 ENST00000295269.5
solute carrier family 9 member A4
chr1_-_39901996 0.59 ENST00000397332.2
MYCL proto-oncogene, bHLH transcription factor
chr11_-_119196769 0.58 ENST00000415318.2
coiled-coil domain containing 153
chr11_-_118565810 0.58 ENST00000672656.2
ENST00000530872.5
ENST00000264021.8
intraflagellar transport 46
chr12_-_56189548 0.56 ENST00000347471.8
ENST00000267064.8
ENST00000394023.7
SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2
chr8_-_42501224 0.56 ENST00000520262.6
ENST00000517366.1
solute carrier family 20 member 2
chr1_-_145910031 0.56 ENST00000369304.8
integrin subunit alpha 10
chr19_+_41354145 0.56 ENST00000604123.5
transmembrane protein 91
chr11_+_117232725 0.56 ENST00000531287.5
ENST00000531452.5
ring finger protein 214
chr1_+_185734362 0.56 ENST00000271588.9
hemicentin 1
chr19_+_18007182 0.56 ENST00000595712.6
arrestin domain containing 2
chr5_+_157743703 0.55 ENST00000286307.6
LSM11, U7 small nuclear RNA associated
chr8_-_144787275 0.55 ENST00000343459.8
ENST00000429371.7
ENST00000534445.1
zinc finger protein 34
chr12_-_95116967 0.55 ENST00000551521.5
FYVE, RhoGEF and PH domain containing 6
chr6_+_35342535 0.54 ENST00000360694.8
ENST00000418635.6
ENST00000448077.6
peroxisome proliferator activated receptor delta
chr14_+_99793329 0.54 ENST00000334192.8
EMAP like 1
chr17_-_63446260 0.54 ENST00000448884.6
ENST00000582297.5
ENST00000360793.8
ENST00000582034.5
ENST00000578072.1
cytochrome b561
chr1_-_212035513 0.54 ENST00000366992.7
ENST00000366993.7
ENST00000440600.6
ENST00000366994.8
integrator complex subunit 7
chr1_-_145910066 0.53 ENST00000539363.2
integrin subunit alpha 10
chr19_-_18941117 0.53 ENST00000600077.5
homer scaffold protein 3
chr11_-_63768762 0.52 ENST00000433688.2
chromosome 11 open reading frame 95
chr17_+_65137344 0.52 ENST00000262406.10
regulator of G protein signaling 9
chr12_+_118376539 0.52 ENST00000543473.2
SDS3 homolog, SIN3A corepressor complex component
chr17_+_65137408 0.51 ENST00000443584.7
ENST00000449996.7
regulator of G protein signaling 9
chr2_-_231530427 0.50 ENST00000305141.5
neuromedin U receptor 1
chr22_+_31082860 0.50 ENST00000619644.4
smoothelin
chr11_-_67356970 0.50 ENST00000532830.5
DNA polymerase delta 4, accessory subunit
chr19_-_33302524 0.50 ENST00000498907.3
CCAAT enhancer binding protein alpha
chr14_+_21978440 0.49 ENST00000390443.3
T cell receptor alpha variable 8-6
chr19_-_35510384 0.49 ENST00000602679.5
ENST00000492341.6
ENST00000472252.6
ENST00000602781.5
ENST00000402589.6
ENST00000458071.5
ENST00000436012.5
ENST00000443640.5
ENST00000450261.1
ENST00000467637.5
ENST00000480502.5
ENST00000474928.5
ENST00000414866.6
ENST00000392206.6
ENST00000488892.5
dermokine
chr17_-_81869934 0.48 ENST00000580685.5
Rho GDP dissociation inhibitor alpha
chr5_-_123423436 0.48 ENST00000328236.10
ENST00000306481.11
centrosomal protein 120
chr10_+_35127162 0.48 ENST00000354759.7
cAMP responsive element modulator
chr13_+_32586443 0.48 ENST00000315596.15
PDS5 cohesin associated factor B
chr11_-_17389323 0.47 ENST00000528731.1
potassium inwardly rectifying channel subfamily J member 11
chr10_+_35126791 0.47 ENST00000474362.5
ENST00000374721.7
cAMP responsive element modulator
chr11_+_117232625 0.47 ENST00000534428.5
ENST00000300650.9
ring finger protein 214
chr1_-_156705742 0.46 ENST00000368221.1
cellular retinoic acid binding protein 2
chr16_+_53054973 0.46 ENST00000447540.6
ENST00000615216.4
ENST00000566029.5
chromodomain helicase DNA binding protein 9
chr17_+_2055094 0.46 ENST00000399849.4
ENST00000619757.5
HIC ZBTB transcriptional repressor 1
chr16_-_90008988 0.46 ENST00000568662.2
dysbindin domain containing 1
chr2_+_90069662 0.46 ENST00000390271.2
immunoglobulin kappa variable 6D-41 (non-functional)
chr9_-_137028271 0.45 ENST00000265662.9
ENST00000371605.7
ATP binding cassette subfamily A member 2
chr3_+_113838772 0.45 ENST00000358160.9
GRAM domain containing 1C
chr12_-_123533705 0.45 ENST00000636882.1
ENST00000376874.9
Rab interacting lysosomal protein like 1
chr14_+_99793375 0.45 ENST00000262233.11
ENST00000556714.5
EMAP like 1
chr5_-_123423337 0.45 ENST00000306467.10
ENST00000675330.1
ENST00000674684.1
centrosomal protein 120
chr19_-_4400418 0.45 ENST00000598564.5
ENST00000417295.6
ENST00000269886.7
SH3 domain containing GRB2 like 1, endophilin A2
chrX_+_77910656 0.44 ENST00000343533.9
ENST00000341514.11
ENST00000645454.1
ENST00000642651.1
ENST00000644362.1
ATPase copper transporting alpha
phosphoglycerate kinase 1
chr15_-_65611236 0.44 ENST00000420799.7
ENST00000313182.6
ENST00000431261.6
ENST00000652388.1
ENST00000442903.3
integrator complex subunit 14
chr19_+_38403105 0.44 ENST00000588262.5
ENST00000252530.9
ENST00000343358.11
family with sequence similarity 98 member C
chr19_-_41353904 0.44 ENST00000221930.6
transforming growth factor beta 1
chr6_+_127266832 0.44 ENST00000356799.6
ENST00000368314.6
ring finger protein 146
chr14_-_91060578 0.44 ENST00000418736.6
ENST00000614987.5
ribosomal protein S6 kinase A5
chr22_+_22594528 0.43 ENST00000390303.3
immunoglobulin lambda variable 3-32 (non-functional)
chr7_-_100573865 0.43 ENST00000622764.3
Sin3A associated protein 25
chr6_+_11537738 0.43 ENST00000379426.2
transmembrane protein 170B
chr6_+_127266875 0.42 ENST00000610162.5
ENST00000608991.5
ENST00000610153.1
ring finger protein 146
chr2_-_153478753 0.41 ENST00000325926.4
reprimo, TP53 dependent G2 arrest mediator homolog
chr9_-_137028223 0.41 ENST00000341511.11
ATP binding cassette subfamily A member 2
chrX_-_55161098 0.41 ENST00000489298.1
ENST00000477847.6
family with sequence similarity 104 member B
chr1_-_156705764 0.40 ENST00000621784.4
ENST00000368220.1
cellular retinoic acid binding protein 2
chr10_+_100999287 0.40 ENST00000370220.1
leucine zipper tumor suppressor 2
chr10_+_35127023 0.40 ENST00000429130.7
ENST00000469949.6
ENST00000460270.5
cAMP responsive element modulator
chr17_+_76000906 0.40 ENST00000448471.2
cyclin dependent kinase 3
chr7_-_122886706 0.38 ENST00000313070.11
ENST00000334010.11
ENST00000615869.4
calcium dependent secretion activator 2
chr3_+_50273119 0.38 ENST00000456560.6
ENST00000418576.3
semaphorin 3B
chr5_-_140346596 0.38 ENST00000230990.7
heparin binding EGF like growth factor
chrX_+_153764178 0.37 ENST00000538966.5
plexin B3
chr17_+_76868396 0.37 ENST00000569840.7
alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B
chr12_+_51424802 0.37 ENST00000453097.7
solute carrier family 4 member 8
chr16_-_11256192 0.37 ENST00000644787.1
ENST00000332029.4
suppressor of cytokine signaling 1
chrX_+_153764233 0.37 ENST00000361971.10
plexin B3
chr15_-_34210011 0.37 ENST00000557877.5
katanin regulatory subunit B1 like 1
chr4_+_74933095 0.37 ENST00000513238.5
prostate androgen-regulated mucin-like protein 1
chr4_+_74933108 0.36 ENST00000307428.7
prostate androgen-regulated mucin-like protein 1
chr6_+_124962420 0.36 ENST00000521654.7
ENST00000560949.5
ring finger protein 217
chr8_-_144326842 0.36 ENST00000528718.6
diacylglycerol O-acyltransferase 1
chrX_+_149881141 0.35 ENST00000535454.5
ENST00000542674.5
ENST00000286482.6
MAGE family member A8
chr16_-_2329687 0.35 ENST00000567910.1
ATP binding cassette subfamily A member 3
chr6_-_44257279 0.35 ENST00000619636.4
solute carrier family 35 member B2
chr12_+_109900518 0.35 ENST00000312777.9
ENST00000536408.2
trichoplein keratin filament binding
chr1_+_145845608 0.35 ENST00000334513.6
nudix hydrolase 17
chr7_+_73667824 0.34 ENST00000324941.5
ENST00000451519.1
VPS37D subunit of ESCRT-I
chr6_-_44257494 0.34 ENST00000393812.4
ENST00000393810.5
ENST00000538577.5
ENST00000537814.2
solute carrier family 35 member B2
chr1_-_36149450 0.34 ENST00000373163.5
trafficking protein particle complex 3
chr13_+_31199959 0.34 ENST00000343307.5
beta 3-glucosyltransferase
chr8_-_144326908 0.34 ENST00000332324.5
diacylglycerol O-acyltransferase 1
chr17_-_7177482 0.33 ENST00000572879.5
asialoglycoprotein receptor 1
chr12_+_109900258 0.33 ENST00000405876.9
trichoplein keratin filament binding
chr7_-_38354517 0.33 ENST00000390345.2
T cell receptor gamma variable 4
chr14_-_20609773 0.33 ENST00000555283.1
ENST00000413502.1
novel protein
ribonuclease A family member 11 (inactive)
chr11_+_925840 0.33 ENST00000448903.7
ENST00000525796.5
ENST00000534328.5
adaptor related protein complex 2 subunit alpha 2
chr4_+_70704713 0.33 ENST00000417478.6
RUN and FYVE domain containing 3
chr17_-_37359076 0.33 ENST00000621960.1
ENST00000614428.4
ENST00000614789.4
acetyl-CoA carboxylase alpha
chr19_+_1266653 0.33 ENST00000586472.5
ENST00000589266.5
cold inducible RNA binding protein
chrX_-_55161156 0.33 ENST00000472571.2
ENST00000332132.8
ENST00000425133.2
ENST00000358460.8
family with sequence similarity 104 member B
chr7_-_100081701 0.32 ENST00000292393.9
ENST00000299667.9
ENST00000413658.6
ENST00000441298.5
ENST00000449785.5
ENST00000412947.6
zinc finger protein 3
chr1_+_151070740 0.32 ENST00000368918.8
GA binding protein transcription factor subunit beta 2
chr11_-_128905697 0.32 ENST00000310799.9
chromosome 11 open reading frame 45
chr1_-_36149464 0.32 ENST00000373166.8
ENST00000373159.1
ENST00000373162.5
ENST00000616074.4
ENST00000616395.4
trafficking protein particle complex 3
chr14_-_54441325 0.32 ENST00000556113.1
ENST00000553660.5
ENST00000216416.9
ENST00000395573.8
ENST00000557690.5
cornichon family AMPA receptor auxiliary protein 1
chr19_-_41353044 0.32 ENST00000600196.2
ENST00000677934.1
transforming growth factor beta 1
chr16_-_31202733 0.32 ENST00000350605.4
ENST00000247470.10
PYD and CARD domain containing
chr19_-_6279921 0.31 ENST00000252674.9
MLLT1 super elongation complex subunit
chr2_-_127642131 0.31 ENST00000426981.5
LIM zinc finger domain containing 2
chr5_+_138352674 0.31 ENST00000314358.10
lysine demethylase 3B
chr5_+_55160161 0.31 ENST00000296734.6
ENST00000515370.1
ENST00000503787.6
glutathione peroxidase 8 (putative)
chr11_+_7088991 0.31 ENST00000306904.7
RBMX like 2
chr15_+_31978056 0.31 ENST00000637183.1
cholinergic receptor nicotinic alpha 7 subunit
chr12_+_56224318 0.30 ENST00000267023.9
ENST00000380198.6
ENST00000341463.5
nucleic acid binding protein 2
chr7_-_38363476 0.30 ENST00000426402.2
T cell receptor gamma variable 2
chrX_+_24693879 0.30 ENST00000379068.8
ENST00000677890.1
ENST00000379059.7
DNA polymerase alpha 1, catalytic subunit
chr22_-_22559229 0.29 ENST00000405655.8
ENST00000406503.1
ENST00000439106.5
ENST00000402697.5
ENST00000543184.5
ENST00000398743.6
PRAME nuclear receptor transcriptional regulator
chr11_-_117232033 0.29 ENST00000524507.6
ENST00000320934.8
ENST00000532301.5
ENST00000676339.1
ENST00000540028.5
proprotein convertase subtilisin/kexin type 7
chr19_+_8413270 0.29 ENST00000381035.8
ENST00000595142.5
ENST00000601724.5
ENST00000601283.5
ENST00000215555.7
ENST00000595213.1
membrane associated ring-CH-type finger 2
chr1_-_39901861 0.29 ENST00000372816.3
ENST00000372815.1
MYCL proto-oncogene, bHLH transcription factor
chr17_-_45132505 0.28 ENST00000619929.5
phospholipase C delta 3
chr12_-_949519 0.28 ENST00000397230.6
ENST00000542785.5
ENST00000544742.5
ENST00000536177.5
ENST00000541619.1
RAD52 homolog, DNA repair protein
chr3_+_50155024 0.28 ENST00000414301.5
ENST00000450338.5
ENST00000413852.5
semaphorin 3F
chr1_-_109112733 0.28 ENST00000369948.8
ENST00000369945.7
chromosome 1 open reading frame 194
chr7_-_122886439 0.28 ENST00000412584.6
ENST00000449022.7
calcium dependent secretion activator 2
chr5_-_179623098 0.28 ENST00000630639.1
ENST00000329433.10
ENST00000510411.5
heterogeneous nuclear ribonucleoprotein H1
chr16_-_740934 0.28 ENST00000540986.5
cytosolic iron-sulfur assembly component 3
chr19_-_6481769 0.27 ENST00000381480.7
ENST00000543576.5
ENST00000590173.5
DENN domain containing 1C
chr2_-_166128004 0.27 ENST00000303395.9
ENST00000674923.1
ENST00000637988.1
ENST00000635776.1
sodium voltage-gated channel alpha subunit 1
chr11_+_64251483 0.27 ENST00000279230.12
ENST00000540288.5
ENST00000325234.5
phospholipase C beta 3
chr16_-_740980 0.27 ENST00000251588.7
cytosolic iron-sulfur assembly component 3
chr7_-_38359120 0.27 ENST00000390346.2
T cell receptor gamma variable 3
chr16_+_23557714 0.27 ENST00000567212.5
ENST00000567264.1
ENST00000395878.8
ubiquitin family domain containing 1
chr16_-_15856994 0.27 ENST00000576790.7
ENST00000396324.7
ENST00000300036.6
ENST00000452625.7
myosin heavy chain 11
chr12_+_51048318 0.27 ENST00000550929.5
ENST00000550442.5
ENST00000549340.5
ENST00000548209.5
ENST00000548251.5
ENST00000550814.5
ENST00000547660.5
ENST00000262055.9
ENST00000548401.1
ENST00000418425.6
ENST00000547008.5
ENST00000552739.5
LETM1 domain containing 1
chr2_+_90021567 0.26 ENST00000436451.2
immunoglobulin kappa variable 6D-21 (non-functional)
chr11_-_8263858 0.26 ENST00000534484.1
ENST00000335790.8
LIM domain only 1
chr19_-_1513003 0.26 ENST00000330475.9
ENST00000586272.5
ENST00000590562.5
ADAMTS like 5
chr12_+_47963557 0.26 ENST00000256686.10
ENST00000549288.5
ENST00000429772.7
ENST00000552561.5
ENST00000546749.5
ENST00000552546.5
ENST00000550552.5
transmembrane protein 106C
chr8_+_73294594 0.26 ENST00000240285.10
retinol dehydrogenase 10
chr22_-_22559073 0.26 ENST00000420709.5
ENST00000398741.5
PRAME nuclear receptor transcriptional regulator
chr16_-_90019414 0.26 ENST00000002501.11
dysbindin domain containing 1
chr1_+_156860857 0.25 ENST00000524377.7
neurotrophic receptor tyrosine kinase 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0099557 trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission(GO:0099557)
0.3 1.3 GO:0010725 regulation of primitive erythrocyte differentiation(GO:0010725) eosinophil fate commitment(GO:0035854)
0.3 1.5 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.3 1.4 GO:0044828 miRNA catabolic process(GO:0010587) negative regulation by host of viral genome replication(GO:0044828) response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
0.3 0.8 GO:0051695 actin filament uncapping(GO:0051695)
0.2 1.1 GO:0035990 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.2 1.0 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.2 0.8 GO:0052553 induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) modulation by symbiont of host defense response(GO:0052031) induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) modulation by virus of host immune response(GO:0075528)
0.2 0.6 GO:2000170 positive regulation of peptidyl-cysteine S-nitrosylation(GO:2000170)
0.2 0.5 GO:0071344 diphosphate metabolic process(GO:0071344)
0.2 0.8 GO:1901202 negative regulation of extracellular matrix assembly(GO:1901202)
0.1 0.4 GO:0060003 copper ion export(GO:0060003)
0.1 0.7 GO:0035948 N-terminal peptidyl-lysine acetylation(GO:0018076) positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.1 0.7 GO:0046963 3'-phosphoadenosine 5'-phosphosulfate transport(GO:0046963) 3'-phospho-5'-adenylyl sulfate transmembrane transport(GO:1902559)
0.1 0.8 GO:0021553 olfactory nerve development(GO:0021553)
0.1 0.9 GO:0032377 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.1 0.5 GO:1903575 cornified envelope assembly(GO:1903575)
0.1 0.4 GO:1903445 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.1 0.9 GO:2000980 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.1 0.7 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.1 0.3 GO:0002585 positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) positive regulation of antigen processing and presentation of peptide antigen(GO:0002585) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588)
0.1 0.9 GO:0010825 positive regulation of centrosome duplication(GO:0010825) interkinetic nuclear migration(GO:0022027)
0.1 0.3 GO:1903028 positive regulation of opsonization(GO:1903028)
0.1 2.2 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.1 0.6 GO:0090206 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.1 0.5 GO:0019348 polyprenol catabolic process(GO:0016095) dolichol metabolic process(GO:0019348)
0.1 0.3 GO:0034147 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429)
0.1 0.2 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.1 1.2 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.1 0.6 GO:0097461 copper ion import(GO:0015677) ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.1 0.2 GO:0031959 mineralocorticoid receptor signaling pathway(GO:0031959) regulation of cardiac vascular smooth muscle cell differentiation(GO:2000722) positive regulation of cardiac vascular smooth muscle cell differentiation(GO:2000724)
0.1 0.3 GO:0031455 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.1 0.8 GO:0006776 vitamin A metabolic process(GO:0006776)
0.1 0.9 GO:0036089 cleavage furrow formation(GO:0036089)
0.1 0.3 GO:0006272 leading strand elongation(GO:0006272)
0.1 1.1 GO:0002138 retinoic acid biosynthetic process(GO:0002138)
0.1 0.6 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1 0.3 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.1 0.3 GO:0034628 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.1 0.4 GO:2000819 regulation of nucleotide-excision repair(GO:2000819)
0.1 0.2 GO:0061445 endocardial cell fate commitment(GO:0060957) endocardial cushion cell fate commitment(GO:0061445)
0.1 0.3 GO:1990167 protein K6-linked deubiquitination(GO:0044313) protein K27-linked deubiquitination(GO:1990167)
0.1 0.7 GO:0010593 negative regulation of lamellipodium assembly(GO:0010593)
0.1 0.7 GO:1990504 dense core granule exocytosis(GO:1990504)
0.1 0.5 GO:0071316 cellular response to nicotine(GO:0071316)
0.1 1.2 GO:0007172 signal complex assembly(GO:0007172)
0.1 0.9 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.1 0.8 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.1 0.4 GO:0051541 elastin metabolic process(GO:0051541)
0.1 0.2 GO:1904808 regulation of protein oxidation(GO:1904806) positive regulation of protein oxidation(GO:1904808)
0.1 0.7 GO:0036155 acylglycerol acyl-chain remodeling(GO:0036155)
0.1 2.0 GO:0060065 uterus development(GO:0060065)
0.1 0.3 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.1 0.2 GO:1900082 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.1 0.2 GO:0036233 glycine import(GO:0036233)
0.1 0.2 GO:1990637 response to prolactin(GO:1990637)
0.1 0.3 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.1 0.2 GO:0018008 N-terminal peptidyl-glycine N-myristoylation(GO:0018008)
0.1 0.3 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.1 3.6 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 0.1 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.0 0.2 GO:1990502 dense core granule maturation(GO:1990502)
0.0 0.6 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.2 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
0.0 0.3 GO:0050893 sensory processing(GO:0050893)
0.0 0.1 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.0 0.7 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 1.4 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.2 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.0 1.0 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.0 0.0 GO:0060382 regulation of DNA strand elongation(GO:0060382)
0.0 0.4 GO:0010533 regulation of activation of Janus kinase activity(GO:0010533)
0.0 0.1 GO:0019483 uracil catabolic process(GO:0006212) beta-alanine biosynthetic process(GO:0019483)
0.0 0.3 GO:0036486 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486)
0.0 0.7 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.0 0.2 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.4 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.8 GO:0009642 response to light intensity(GO:0009642)
0.0 0.5 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.2 GO:0050917 sensory perception of umami taste(GO:0050917)
0.0 1.0 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 1.5 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.5 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.1 GO:0071529 cementum mineralization(GO:0071529)
0.0 1.1 GO:0014850 response to muscle activity(GO:0014850)
0.0 0.2 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.0 0.6 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0 0.2 GO:0035754 B cell chemotaxis(GO:0035754)
0.0 0.5 GO:0071285 cellular response to lithium ion(GO:0071285)
0.0 0.5 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.4 GO:0045023 G0 to G1 transition(GO:0045023)
0.0 0.2 GO:0035865 cellular response to potassium ion(GO:0035865)
0.0 0.4 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.0 0.2 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.1 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 0.5 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.1 GO:0098971 anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
0.0 0.3 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.1 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.0 0.2 GO:1904100 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.0 0.2 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 1.2 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.2 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.3 GO:0072718 response to cisplatin(GO:0072718)
0.0 0.2 GO:0090649 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.0 0.1 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 0.1 GO:0036337 Fas signaling pathway(GO:0036337) regulation of Fas signaling pathway(GO:1902044) positive regulation of blood vessel remodeling(GO:2000504)
0.0 0.3 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.0 0.6 GO:0097320 membrane tubulation(GO:0097320)
0.0 0.2 GO:0090063 microtubule anchoring at centrosome(GO:0034454) positive regulation of microtubule nucleation(GO:0090063)
0.0 0.1 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.1 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.0 2.4 GO:0035690 cellular response to drug(GO:0035690)
0.0 1.3 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 0.3 GO:0035878 nail development(GO:0035878)
0.0 0.1 GO:0042732 D-xylose metabolic process(GO:0042732)
0.0 0.2 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 0.2 GO:0003057 regulation of the force of heart contraction by chemical signal(GO:0003057)
0.0 0.1 GO:0021759 globus pallidus development(GO:0021759)
0.0 0.3 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.0 0.2 GO:0090625 mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.0 0.5 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 1.4 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.2 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.1 GO:2000721 positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.0 0.9 GO:0002042 cell migration involved in sprouting angiogenesis(GO:0002042)
0.0 0.1 GO:0071504 cellular response to heparin(GO:0071504)
0.0 0.1 GO:0048318 axial mesoderm development(GO:0048318)
0.0 1.1 GO:0051972 regulation of telomerase activity(GO:0051972)
0.0 0.3 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.2 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.3 GO:0036109 alpha-linolenic acid metabolic process(GO:0036109)
0.0 0.2 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.1 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 0.0 GO:2000813 negative regulation of barbed-end actin filament capping(GO:2000813)
0.0 0.1 GO:1904021 negative regulation of G-protein coupled receptor internalization(GO:1904021)
0.0 0.7 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.5 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.0 1.8 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0 0.1 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 0.1 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.0 0.2 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 0.7 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.1 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 0.8 GO:0007405 neuroblast proliferation(GO:0007405)
0.0 0.8 GO:0050771 negative regulation of axonogenesis(GO:0050771)
0.0 1.1 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 0.2 GO:0015671 oxygen transport(GO:0015671)
0.0 0.3 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.0 0.4 GO:0015012 heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.0 0.0 GO:2000984 regulation of ATP citrate synthase activity(GO:2000983) negative regulation of ATP citrate synthase activity(GO:2000984)
0.0 0.1 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.0 1.0 GO:0048207 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.0 0.2 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.3 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 0.3 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.2 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 0.1 GO:0030238 male sex determination(GO:0030238)
0.0 0.1 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.0 0.0 GO:0006924 activation-induced cell death of T cells(GO:0006924)
0.0 0.2 GO:2000105 positive regulation of DNA-dependent DNA replication(GO:2000105)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0000814 ESCRT II complex(GO:0000814)
0.2 1.1 GO:0034680 integrin alpha10-beta1 complex(GO:0034680)
0.2 2.0 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.2 1.4 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1 0.9 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.1 0.5 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.1 0.9 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.1 0.7 GO:0000125 PCAF complex(GO:0000125)
0.1 1.0 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.1 0.6 GO:0005683 U7 snRNP(GO:0005683)
0.1 0.8 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 0.3 GO:0070876 SOSS complex(GO:0070876)
0.1 0.3 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.1 0.2 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 0.4 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.1 0.2 GO:0097135 X chromosome(GO:0000805) cyclin E2-CDK2 complex(GO:0097135)
0.1 0.5 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.1 0.9 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 1.2 GO:0031045 dense core granule(GO:0031045)
0.0 0.6 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.3 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.7 GO:0030008 TRAPP complex(GO:0030008)
0.0 1.0 GO:0036020 endolysosome membrane(GO:0036020)
0.0 1.4 GO:0071564 npBAF complex(GO:0071564)
0.0 0.5 GO:0045179 apical cortex(GO:0045179)
0.0 1.2 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.2 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.5 GO:0032039 integrator complex(GO:0032039)
0.0 4.0 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 1.0 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.2 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.3 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.1 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.0 0.1 GO:0097233 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.0 0.2 GO:0070847 core mediator complex(GO:0070847)
0.0 0.1 GO:0036117 hyaluranon cable(GO:0036117)
0.0 0.5 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.2 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.2 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.3 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.2 GO:0031298 replication fork protection complex(GO:0031298)
0.0 0.8 GO:0031527 filopodium membrane(GO:0031527)
0.0 3.6 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.1 GO:0034678 integrin alpha8-beta1 complex(GO:0034678)
0.0 0.2 GO:0000322 storage vacuole(GO:0000322)
0.0 1.1 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.6 GO:0030137 COPI-coated vesicle(GO:0030137)
0.0 0.1 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.2 GO:0005869 dynactin complex(GO:0005869)
0.0 0.2 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.1 GO:0001739 sex chromatin(GO:0001739)
0.0 2.0 GO:0042641 actomyosin(GO:0042641)
0.0 0.4 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.0 1.0 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.9 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.1 GO:1990909 Wnt signalosome(GO:1990909)
0.0 0.2 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.2 GO:0005858 axonemal dynein complex(GO:0005858)
0.0 1.8 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.2 GO:0016600 flotillin complex(GO:0016600)
0.0 1.2 GO:0045178 basal part of cell(GO:0045178)
0.0 0.0 GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 0.1 GO:0089701 U2AF(GO:0089701)
0.0 0.4 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.1 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.0 0.3 GO:0032982 myosin filament(GO:0032982)
0.0 1.0 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.5 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.3 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 5.2 GO:0005667 transcription factor complex(GO:0005667)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.9 GO:0008046 axon guidance receptor activity(GO:0008046)
0.2 0.6 GO:0071209 U7 snRNA binding(GO:0071209)
0.2 0.7 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.1 0.4 GO:0004618 copper-exporting ATPase activity(GO:0004008) phosphoglycerate kinase activity(GO:0004618) copper-transporting ATPase activity(GO:0043682)
0.1 0.7 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.1 1.1 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.1 0.5 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.1 0.6 GO:0031711 tripeptidyl-peptidase activity(GO:0008240) peptidyl-dipeptidase activity(GO:0008241) bradykinin receptor binding(GO:0031711) metallodipeptidase activity(GO:0070573)
0.1 0.8 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 0.8 GO:0010465 neurotrophin p75 receptor binding(GO:0005166) nerve growth factor receptor activity(GO:0010465)
0.1 0.8 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.1 0.6 GO:0001888 glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888)
0.1 0.5 GO:0047751 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) cholestenone 5-alpha-reductase activity(GO:0047751)
0.1 0.6 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.1 0.3 GO:0032090 Pyrin domain binding(GO:0032090)
0.1 0.7 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.1 0.6 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1 0.7 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.1 0.5 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.1 0.2 GO:0000248 C-5 sterol desaturase activity(GO:0000248) sterol desaturase activity(GO:0070704)
0.1 0.2 GO:0004577 N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity(GO:0004577)
0.1 1.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.2 GO:0031755 endothelial differentiation G-protein coupled receptor binding(GO:0031753) Edg-2 lysophosphatidic acid receptor binding(GO:0031755)
0.1 0.5 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.1 1.4 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 0.3 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.1 1.2 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.1 0.3 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309)
0.1 0.2 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.1 0.7 GO:0022821 potassium:proton antiporter activity(GO:0015386) potassium ion antiporter activity(GO:0022821)
0.1 0.2 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.1 0.2 GO:0019107 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
0.1 0.2 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.0 0.2 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.5 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.3 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.1 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.0 0.5 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.1 GO:0098918 structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.0 0.8 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 1.0 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.4 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 1.0 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.1 GO:0047325 inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol-1,3,4-trisphosphate 6-kinase activity(GO:0052725) inositol-1,3,4-trisphosphate 5-kinase activity(GO:0052726) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) inositol-3,4,6-trisphosphate 1-kinase activity(GO:0052835)
0.0 0.9 GO:0019841 retinol binding(GO:0019841)
0.0 3.6 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.3 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 1.4 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 1.4 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.1 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 1.0 GO:0017166 vinculin binding(GO:0017166)
0.0 0.1 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.2 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.2 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.0 0.3 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.7 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.2 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.3 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.2 GO:0043426 MRF binding(GO:0043426)
0.0 0.2 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.2 GO:0030284 estrogen receptor activity(GO:0030284)
0.0 1.3 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.6 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 1.9 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.9 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.8 GO:0036041 long-chain fatty acid binding(GO:0036041)
0.0 1.1 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.9 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.3 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.6 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 1.2 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.8 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.1 GO:0070404 NADH binding(GO:0070404)
0.0 0.2 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0 0.1 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 0.2 GO:0019826 oxygen sensor activity(GO:0019826)
0.0 0.3 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.3 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 1.1 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.7 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.1 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 2.5 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.7 GO:0030332 cyclin binding(GO:0030332)
0.0 0.2 GO:0019966 interleukin-1 binding(GO:0019966)
0.0 0.9 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.6 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.2 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.6 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 0.3 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.1 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.1 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.1 GO:0046935 phosphatidylinositol 3-kinase regulator activity(GO:0035014) 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.2 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.2 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.3 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.2 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.0 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.0 0.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.4 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.5 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.0 0.2 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.2 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 0.0 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.8 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.3 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.8 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 1.5 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 0.4 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 1.8 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 1.4 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 2.9 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.8 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.8 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 1.3 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 1.4 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 1.7 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.4 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 1.4 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.8 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.7 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.2 ST STAT3 PATHWAY STAT3 Pathway
0.0 0.2 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.7 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.1 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.2 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.2 PID ALK2 PATHWAY ALK2 signaling events
0.0 1.0 PID REG GR PATHWAY Glucocorticoid receptor regulatory network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR Genes involved in Downstream signaling of activated FGFR
0.0 0.8 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.0 0.8 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.9 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.6 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.8 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.6 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.9 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 2.7 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.0 0.7 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.5 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.8 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.7 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.3 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.3 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.4 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.3 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.3 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.5 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.3 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.4 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 2.6 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 1.0 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.0 0.2 REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0 0.3 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0 0.4 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex