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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for RBPJ

Z-value: 1.22

Motif logo

Transcription factors associated with RBPJ

Gene Symbol Gene ID Gene Info
ENSG00000168214.21 RBPJ

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RBPJhg38_v1_chr4_+_26320975_26321030-0.628.6e-04Click!

Activity profile of RBPJ motif

Sorted Z-values of RBPJ motif

Network of associatons between targets according to the STRING database.

First level regulatory network of RBPJ

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr4_+_155667654 16.83 ENST00000513574.1
guanylate cyclase 1 soluble subunit alpha 1
chr4_+_155667198 11.41 ENST00000296518.11
guanylate cyclase 1 soluble subunit alpha 1
chr4_+_155667096 8.41 ENST00000393832.7
guanylate cyclase 1 soluble subunit alpha 1
chr7_+_94394886 4.27 ENST00000297268.11
ENST00000620463.1
collagen type I alpha 2 chain
chr6_-_75493629 3.71 ENST00000393004.6
filamin A interacting protein 1
chr1_+_61404076 3.49 ENST00000357977.5
nuclear factor I A
chr12_-_48865863 3.25 ENST00000309739.6
Rho family GTPase 1
chr6_-_75493773 3.00 ENST00000237172.12
filamin A interacting protein 1
chr8_+_67952028 2.70 ENST00000288368.5
phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2
chr3_-_142029108 2.58 ENST00000497579.5
transcription factor Dp-2
chr8_-_79767843 2.34 ENST00000337919.9
hes related family bHLH transcription factor with YRPW motif 1
chr8_-_79767462 2.26 ENST00000674295.1
ENST00000518733.1
ENST00000674418.1
ENST00000674358.1
ENST00000354724.8
hes related family bHLH transcription factor with YRPW motif 1
chr13_-_19782923 1.93 ENST00000338910.9
paraspeckle component 1
chr7_+_102912983 1.85 ENST00000339431.9
ENST00000249377.4
leucine rich repeat containing 17
chr10_-_33334898 1.83 ENST00000395995.5
neuropilin 1
chr6_+_30884063 1.80 ENST00000511510.5
ENST00000376569.7
ENST00000376570.8
ENST00000504927.5
discoidin domain receptor tyrosine kinase 1
chr13_-_19782970 1.80 ENST00000427943.1
ENST00000619300.4
paraspeckle component 1
chr3_+_46407558 1.73 ENST00000357392.4
ENST00000400880.3
ENST00000433848.1
C-C motif chemokine receptor like 2
chr12_-_7695752 1.71 ENST00000329913.4
growth differentiation factor 3
chr10_-_33334625 1.70 ENST00000374875.5
ENST00000374822.8
ENST00000374867.7
neuropilin 1
chr6_+_30884353 1.68 ENST00000428153.6
ENST00000376568.8
ENST00000452441.5
ENST00000515219.5
discoidin domain receptor tyrosine kinase 1
chr9_+_99821876 1.63 ENST00000395097.7
nuclear receptor subfamily 4 group A member 3
chr7_-_22220226 1.52 ENST00000420196.5
Rap guanine nucleotide exchange factor 5
chr3_+_194136138 1.49 ENST00000232424.4
hes family bHLH transcription factor 1
chr6_-_32224060 1.47 ENST00000375023.3
notch receptor 4
chr1_-_1000088 1.46 ENST00000304952.11
hes family bHLH transcription factor 4
chr7_-_120858066 1.46 ENST00000222747.8
tetraspanin 12
chr5_-_88823763 1.41 ENST00000635898.1
ENST00000626391.2
ENST00000628656.2
myocyte enhancer factor 2C
chr10_-_33335074 1.40 ENST00000432372.6
neuropilin 1
chr1_-_1000139 1.33 ENST00000428771.6
hes family bHLH transcription factor 4
chr8_-_126557691 1.23 ENST00000652209.1
LRAT domain containing 2
chr9_+_99821846 1.21 ENST00000338488.8
ENST00000618101.4
nuclear receptor subfamily 4 group A member 3
chr3_+_37975773 1.20 ENST00000436654.1
CTD small phosphatase like
chr5_-_88877967 1.18 ENST00000508610.5
ENST00000636294.1
myocyte enhancer factor 2C
chr1_-_85404494 1.17 ENST00000633113.1
dimethylarginine dimethylaminohydrolase 1
chr1_-_999981 1.16 ENST00000484667.2
hes family bHLH transcription factor 4
chr15_-_70097874 1.14 ENST00000557997.5
ENST00000317509.12
ENST00000451782.7
ENST00000627388.2
TLE family member 3, transcriptional corepressor
chr8_+_122781621 1.13 ENST00000314393.6
zinc fingers and homeoboxes 2
chr11_-_119340816 1.12 ENST00000528368.3
C1q and TNF related 5
chr8_-_100336184 1.11 ENST00000519527.5
ENST00000522369.5
ring finger protein 19A, RBR E3 ubiquitin protein ligase
chr3_-_100993507 1.07 ENST00000284322.10
ABI family member 3 binding protein
chr3_-_100993409 1.06 ENST00000471714.6
ABI family member 3 binding protein
chr11_-_119340544 1.06 ENST00000530681.2
C1q and TNF related 5
chr15_-_70097852 1.03 ENST00000559191.5
TLE family member 3, transcriptional corepressor
chr17_+_2796404 1.00 ENST00000366401.8
ENST00000254695.13
ENST00000542807.1
RAP1 GTPase activating protein 2
chr2_-_110473041 0.96 ENST00000632897.1
ENST00000413601.3
LIM zinc finger domain containing 4
chr13_-_74133892 0.94 ENST00000377669.7
Kruppel like factor 12
chr2_+_109898685 0.92 ENST00000480744.2
LIM zinc finger domain containing 3
chr3_-_184017863 0.92 ENST00000427120.6
ENST00000334444.11
ENST00000392579.6
ENST00000382494.6
ENST00000265586.10
ENST00000446941.2
ATP binding cassette subfamily C member 5
chr10_+_111077021 0.82 ENST00000280155.4
adrenoceptor alpha 2A
chr12_+_6828377 0.82 ENST00000290510.10
prolyl 3-hydroxylase 3
chr5_-_140564245 0.81 ENST00000412920.7
ENST00000511201.2
ENST00000354402.9
ENST00000356738.6
amyloid beta precursor protein binding family B member 3
chr7_-_120857124 0.78 ENST00000441017.5
ENST00000424710.5
ENST00000433758.5
tetraspanin 12
chr2_+_218270392 0.69 ENST00000248451.7
ENST00000273077.9
PNKD metallo-beta-lactamase domain containing
chr16_+_58025745 0.66 ENST00000219271.4
matrix metallopeptidase 15
chr7_-_120858303 0.65 ENST00000415871.5
ENST00000430985.1
tetraspanin 12
chr14_+_24232422 0.65 ENST00000620807.4
ENST00000355299.8
ENST00000559836.5
guanosine monophosphate reductase 2
chr17_-_58529277 0.64 ENST00000579371.5
septin 4
chr1_+_36224410 0.63 ENST00000469141.6
ENST00000648638.1
ENST00000354618.10
thyroid hormone receptor associated protein 3
chr13_+_39038347 0.62 ENST00000379599.6
ENST00000379600.8
NHL repeat containing 3
chr13_+_39038292 0.62 ENST00000470258.5
NHL repeat containing 3
chr10_+_122560639 0.60 ENST00000344338.7
ENST00000330163.8
ENST00000652446.2
ENST00000666315.1
ENST00000368955.7
ENST00000368909.7
ENST00000368956.6
ENST00000619379.1
deleted in malignant brain tumors 1
chr17_-_58529344 0.59 ENST00000317268.7
septin 4
chr17_-_58529303 0.59 ENST00000580844.5
septin 4
chr21_+_37420299 0.58 ENST00000455097.6
ENST00000643854.1
ENST00000645424.1
ENST00000642309.1
ENST00000645774.1
ENST00000398956.2
dual specificity tyrosine phosphorylation regulated kinase 1A
chr10_+_122560751 0.58 ENST00000338354.10
ENST00000664692.1
ENST00000653442.1
ENST00000664974.1
deleted in malignant brain tumors 1
chr10_-_48251757 0.58 ENST00000305531.3
FERM and PDZ domain containing 2
chr16_+_85611401 0.57 ENST00000405402.6
Gse1 coiled-coil protein
chr10_+_122560679 0.56 ENST00000657942.1
deleted in malignant brain tumors 1
chr10_-_73168052 0.55 ENST00000430082.6
ENST00000454759.6
ENST00000413026.1
ENST00000453402.5
ecdysoneless cell cycle regulator
chr11_+_66616606 0.54 ENST00000393979.3
ENST00000409372.1
ENST00000310137.5
ENST00000443702.1
ENST00000409738.4
ENST00000412278.2
ENST00000500635.2
RNA binding motif protein 14
RBM14-RBM4 readthrough
chr5_+_42423433 0.53 ENST00000230882.9
growth hormone receptor
chr10_-_73167961 0.53 ENST00000372979.9
ecdysoneless cell cycle regulator
chr11_-_64879709 0.53 ENST00000621096.4
EH domain containing 1
chr5_-_137735997 0.52 ENST00000505853.1
kelch like family member 3
chr11_-_64879675 0.52 ENST00000359393.6
ENST00000433803.1
ENST00000411683.1
EH domain containing 1
chrX_+_123961696 0.51 ENST00000371145.8
ENST00000371157.7
ENST00000371144.7
stromal antigen 2
chr11_+_66744618 0.50 ENST00000524551.5
ENST00000525908.6
ENST00000540737.7
ENST00000527634.5
chromosome 11 open reading frame 80
chr15_-_52529050 0.49 ENST00000399231.7
myosin VA
chr2_+_169733811 0.49 ENST00000392647.7
kelch like family member 23
chr17_-_16215520 0.49 ENST00000582357.5
ENST00000436828.5
ENST00000268712.8
ENST00000411510.5
ENST00000395857.7
nuclear receptor corepressor 1
chr11_-_67523396 0.48 ENST00000353903.9
ENST00000294288.5
calcium binding protein 2
chr7_+_30771388 0.47 ENST00000265299.6
MINDY lysine 48 deubiquitinase 4
chr1_-_204166334 0.46 ENST00000272190.9
renin
chr9_-_101594918 0.46 ENST00000374806.2
protein phosphatase 3 regulatory subunit B, beta
chr3_+_159852933 0.43 ENST00000482804.1
schwannomin interacting protein 1
chr2_-_24328113 0.42 ENST00000622089.4
intersectin 2
chr19_+_50203607 0.42 ENST00000642316.2
ENST00000425460.6
ENST00000440075.6
ENST00000376970.6
ENST00000599920.5
myosin heavy chain 14
chr9_-_101594995 0.42 ENST00000636434.1
protein phosphatase 3 regulatory subunit B, beta
chr14_-_24232332 0.41 ENST00000534348.5
ENST00000524927.1
ENST00000250495.10
NEDD8-MDP1 readthrough
NEDD8 ubiquitin like modifier
chr11_+_66744831 0.40 ENST00000642265.1
ENST00000532565.6
chromosome 11 open reading frame 80
chrX_+_123960519 0.38 ENST00000455404.5
ENST00000218089.13
stromal antigen 2
chr14_-_52950992 0.38 ENST00000343279.8
ENST00000399304.7
ENST00000395631.6
ENST00000341590.8
fermitin family member 2
chr10_+_73168111 0.37 ENST00000242505.11
family with sequence similarity 149 member B1
chr11_+_111918900 0.36 ENST00000278601.6
chromosome 11 open reading frame 52
chr11_-_64744993 0.35 ENST00000377485.5
RAS guanyl releasing protein 2
chr19_-_55179390 0.33 ENST00000590851.5
synaptotagmin 5
chr17_-_28726186 0.33 ENST00000292090.8
TLC domain containing 1
chr8_+_66432475 0.33 ENST00000415254.5
ENST00000396623.8
alcohol dehydrogenase iron containing 1
chr14_+_73136418 0.32 ENST00000557356.5
ENST00000556864.5
ENST00000556533.5
ENST00000556951.5
ENST00000557293.5
ENST00000553719.5
ENST00000553599.5
ENST00000556011.5
ENST00000394157.7
ENST00000357710.8
ENST00000560005.6
ENST00000555254.5
ENST00000554131.5
ENST00000324501.10
ENST00000557037.5
presenilin 1
chr5_+_138179145 0.32 ENST00000508792.5
ENST00000504621.1
kinesin family member 20A
chr16_+_75148478 0.31 ENST00000568079.5
ENST00000570010.6
ENST00000464850.5
ENST00000332307.4
ENST00000393430.6
ZFP1 zinc finger protein
chr22_+_39901075 0.31 ENST00000344138.9
GRB2 related adaptor protein 2
chr5_+_86617967 0.31 ENST00000515763.1
cytochrome c oxidase subunit 7C
chr10_-_107164692 0.29 ENST00000263054.11
sortilin related VPS10 domain containing receptor 1
chr6_+_33208488 0.29 ENST00000374656.5
ring finger protein 1
chr1_-_151008365 0.28 ENST00000361936.9
ENST00000361738.11
MINDY lysine 48 deubiquitinase 1
chr19_+_39997031 0.27 ENST00000599504.5
ENST00000596894.5
ENST00000601138.5
ENST00000347077.9
ENST00000600094.5
zinc finger protein 546
chr10_+_113679523 0.26 ENST00000345633.8
ENST00000614447.4
ENST00000369321.6
caspase 7
chr10_+_113679839 0.26 ENST00000369318.8
ENST00000369315.5
caspase 7
chr20_+_33662310 0.26 ENST00000375222.4
chromosome 20 open reading frame 144
chr17_+_50274447 0.25 ENST00000507382.2
transmembrane protein 92
chr2_+_48568981 0.25 ENST00000394754.5
STON1-GTF2A1L readthrough
chr5_+_138179093 0.24 ENST00000394894.8
kinesin family member 20A
chr10_+_31319125 0.24 ENST00000320985.14
ENST00000560721.6
ENST00000558440.5
ENST00000424869.6
ENST00000542815.7
zinc finger E-box binding homeobox 1
chr6_-_26056460 0.24 ENST00000343677.4
H1.2 linker histone, cluster member
chr5_+_141412979 0.23 ENST00000612503.1
ENST00000398610.3
protocadherin gamma subfamily A, 10
chr12_-_31792290 0.23 ENST00000340398.5
H3.5 histone
chr14_-_92748570 0.22 ENST00000553918.1
ENST00000555699.5
ENST00000334869.9
ENST00000553802.5
ENST00000554397.5
ENST00000554919.5
ENST00000554080.5
ENST00000553371.1
ENST00000557434.5
ENST00000393218.6
legumain
chr16_+_53703963 0.22 ENST00000636218.1
ENST00000637001.1
ENST00000471389.6
ENST00000637969.1
ENST00000640179.1
FTO alpha-ketoglutarate dependent dioxygenase
chr5_+_86617919 0.22 ENST00000247655.4
ENST00000509578.1
cytochrome c oxidase subunit 7C
chr1_-_39639626 0.22 ENST00000372852.4
hes related family bHLH transcription factor with YRPW motif like
chr8_-_67062120 0.21 ENST00000357849.9
COP9 signalosome subunit 5
chr10_-_43648845 0.20 ENST00000374433.7
zinc finger protein 32
chr15_-_77696142 0.19 ENST00000561030.5
leucine rich repeat and Ig domain containing 1
chr20_+_44582549 0.19 ENST00000372886.6
cAMP-dependent protein kinase inhibitor gamma
chr10_-_43648704 0.17 ENST00000395797.1
zinc finger protein 32
chr12_+_56230043 0.17 ENST00000424625.5
ENST00000419753.5
ENST00000454355.7
ENST00000417965.5
ENST00000436633.5
solute carrier family 39 member 5
chr17_+_44349050 0.17 ENST00000639447.1
granulin precursor
chr20_+_31475278 0.17 ENST00000201979.3
RRAD and GEM like GTPase 1
chr11_-_2270584 0.17 ENST00000331289.5
achaete-scute family bHLH transcription factor 2
chr3_+_107523026 0.16 ENST00000416476.6
BBX high mobility group box domain containing
chr15_+_67125707 0.16 ENST00000540846.6
SMAD family member 3
chr12_+_4809176 0.14 ENST00000280684.3
potassium voltage-gated channel subfamily A member 6
chr16_-_1611985 0.14 ENST00000426508.7
intraflagellar transport 140
chr10_+_58385395 0.13 ENST00000487519.6
ENST00000373895.7
transcription factor A, mitochondrial
chr1_+_15847698 0.13 ENST00000375759.8
spen family transcriptional repressor
chr19_-_55597753 0.13 ENST00000587678.1
FLT3 interacting zinc finger 1
chr6_-_134052594 0.13 ENST00000275230.6
solute carrier family 2 member 12
chr16_+_21953341 0.12 ENST00000268379.9
ENST00000561553.5
ENST00000565331.5
ubiquinol-cytochrome c reductase core protein 2
chr1_+_156767526 0.12 ENST00000271526.9
proline rich mitotic checkpoint control factor
chr1_+_43389889 0.12 ENST00000562955.2
ENST00000634258.3
SZT2 subunit of KICSTOR complex
chr19_-_36379185 0.12 ENST00000270001.12
ZFP14 zinc finger protein
chr21_-_6499202 0.12 ENST00000619610.2
ENST00000610664.5
ENST00000639996.1
U2 small nuclear RNA auxiliary factor 1 like 5
chr2_+_218959635 0.11 ENST00000302625.6
cyclin dependent kinase 5 regulatory subunit 2
chr2_-_218270099 0.11 ENST00000248450.9
ENST00000444053.5
angio associated migratory cell protein
chr1_-_91021996 0.10 ENST00000337393.10
zinc finger protein 644
chr12_-_4649043 0.10 ENST00000545990.6
ENST00000228850.6
A-kinase anchoring protein 3
chr1_+_7961894 0.10 ENST00000377491.5
ENST00000377488.5
Parkinsonism associated deglycase
chr12_+_65278919 0.10 ENST00000538045.5
ENST00000642411.1
ENST00000535239.5
ENST00000614640.4
methionine sulfoxide reductase B3
chr18_+_13218195 0.10 ENST00000679167.1
low density lipoprotein receptor class A domain containing 4
chr20_+_31637905 0.09 ENST00000376075.4
cytochrome c oxidase subunit 4I2
chr19_-_38899800 0.08 ENST00000414941.5
ENST00000358931.9
ENST00000392081.6
sirtuin 2
chr2_-_40430257 0.08 ENST00000408028.6
ENST00000332839.8
ENST00000406391.2
ENST00000405901.7
solute carrier family 8 member A1
chr17_-_35930727 0.08 ENST00000616596.4
ENST00000612980.4
ENST00000613308.4
ENST00000619876.4
RAD52 motif containing 1
chr11_+_64285533 0.08 ENST00000538032.5
G protein-coupled receptor 137
chr10_-_33334382 0.08 ENST00000374823.9
ENST00000374821.9
ENST00000374816.7
neuropilin 1
chr2_+_37950432 0.07 ENST00000407257.5
ENST00000417700.6
ENST00000234195.7
ENST00000442857.5
regulator of microtubule dynamics 2
chrX_+_38006551 0.07 ENST00000297875.7
synaptotagmin like 5
chrX_-_21658324 0.07 ENST00000379499.3
kelch like family member 34
chr2_-_79087986 0.06 ENST00000305089.8
regenerating family member 1 beta
chr11_+_7576975 0.05 ENST00000684215.1
ENST00000650027.1
PPFIA binding protein 2
chr1_-_180502536 0.05 ENST00000367595.4
acyl-CoA binding domain containing 6
chr5_+_38445539 0.05 ENST00000397210.7
ENST00000506135.5
ENST00000508131.5
EGF like, fibronectin type III and laminin G domains
chr6_-_31542339 0.05 ENST00000458640.5
DExD-box helicase 39B
chr7_+_128862841 0.04 ENST00000249289.5
ENST00000492758.1
ATPase H+ transporting V1 subunit F
chr19_+_36687579 0.03 ENST00000682579.1
ENST00000536254.6
zinc finger protein 567
chr19_-_38899529 0.03 ENST00000249396.12
ENST00000437828.5
sirtuin 2
chr1_+_113390495 0.03 ENST00000307546.14
membrane associated guanylate kinase, WW and PDZ domain containing 3
chr16_-_57798008 0.03 ENST00000421376.6
kinesin family member C3
chrX_-_153830527 0.03 ENST00000393758.7
ENST00000544474.5
PDZ domain containing 4
chr11_-_101583985 0.02 ENST00000344327.8
transient receptor potential cation channel subfamily C member 6
chr17_-_41481140 0.02 ENST00000246639.6
ENST00000393989.1
keratin 35
chr8_-_86230360 0.02 ENST00000419776.2
ENST00000297524.8
solute carrier family 7 member 13
chr15_-_43879835 0.01 ENST00000636859.1
FERM domain containing 5
chr19_-_42242526 0.01 ENST00000222330.8
ENST00000676537.1
glycogen synthase kinase 3 alpha
chr15_+_40405787 0.01 ENST00000610693.5
ENST00000479013.7
ENST00000487418.8
isovaleryl-CoA dehydrogenase
chr1_+_151008412 0.01 ENST00000271620.8
ENST00000650332.1
ENST00000450884.5
ENST00000368937.5
ENST00000431193.5
ENST00000368936.5
prune exopolyphosphatase 1
chr19_+_7595830 0.01 ENST00000160298.9
ENST00000446248.4
calmodulin regulated spectrin associated protein family member 3
chr10_-_95441015 0.00 ENST00000371241.5
ENST00000354106.7
ENST00000371239.5
ENST00000361941.7
ENST00000277982.9
ENST00000371245.7
sorbin and SH3 domain containing 1
chr19_+_43596480 0.00 ENST00000533118.5
zinc finger protein 576
chr19_-_39204254 0.00 ENST00000318438.7
syncollin
chr12_+_65279092 0.00 ENST00000646299.1
methionine sulfoxide reductase B3
chr5_-_138178599 0.00 ENST00000454473.5
ENST00000418329.5
ENST00000254900.10
ENST00000230901.9
ENST00000402931.5
ENST00000411594.6
ENST00000430331.1
bromodomain containing 8

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.2 GO:0061027 umbilical cord morphogenesis(GO:0036304) umbilical cord development(GO:0061027)
1.3 5.0 GO:1904835 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.7 2.8 GO:0032765 positive regulation of mast cell cytokine production(GO:0032765)
0.5 1.5 GO:0060164 trochlear nerve development(GO:0021558) negative regulation of auditory receptor cell differentiation(GO:0045608) regulation of timing of neuron differentiation(GO:0060164)
0.4 3.5 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.3 2.6 GO:0003172 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.3 4.6 GO:0043589 skin morphogenesis(GO:0043589)
0.3 1.7 GO:0048859 formation of anatomical boundary(GO:0048859)
0.2 0.7 GO:0061727 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.2 0.8 GO:0032811 negative regulation of epinephrine secretion(GO:0032811) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625)
0.2 1.8 GO:0048539 bone marrow development(GO:0048539)
0.2 1.7 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.2 3.3 GO:0016322 neuron remodeling(GO:0016322)
0.2 1.7 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 1.0 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.1 0.5 GO:0072156 distal tubule morphogenesis(GO:0072156)
0.1 3.5 GO:0072189 ureter development(GO:0072189)
0.1 0.3 GO:0015993 molecular hydrogen transport(GO:0015993)
0.1 0.5 GO:0051643 endoplasmic reticulum localization(GO:0051643)
0.1 0.5 GO:0072367 regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.1 0.5 GO:0000255 allantoin metabolic process(GO:0000255)
0.1 0.9 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.1 0.2 GO:0035552 oxidative single-stranded DNA demethylation(GO:0035552)
0.1 2.9 GO:0010842 retina layer formation(GO:0010842)
0.1 0.5 GO:0072734 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.1 1.2 GO:1900038 negative regulation of cellular response to hypoxia(GO:1900038)
0.1 0.5 GO:0002018 renin-angiotensin regulation of aldosterone production(GO:0002018)
0.1 0.9 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.1 2.4 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.1 GO:1902958 neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036482) positive regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902958) regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903383) negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903384)
0.0 0.5 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.0 0.1 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.2 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.0 0.2 GO:0072014 proximal tubule development(GO:0072014)
0.0 0.2 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.0 0.2 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.1 GO:1900195 positive regulation of oocyte maturation(GO:1900195) positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia(GO:2000777)
0.0 0.1 GO:0021722 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.0 0.8 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.0 2.0 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 2.2 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 0.6 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.0 0.6 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.6 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.0 0.6 GO:0043101 purine-containing compound salvage(GO:0043101)
0.0 0.6 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.0 2.7 GO:0042752 regulation of circadian rhythm(GO:0042752)
0.0 0.1 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.4 GO:0033622 integrin activation(GO:0033622)
0.0 1.6 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 0.2 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.1 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.2 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.2 GO:0042359 vitamin D metabolic process(GO:0042359)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 5.0 GO:0097443 sorting endosome(GO:0097443)
0.3 3.7 GO:0042382 paraspeckles(GO:0042382)
0.3 4.3 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.2 0.5 GO:0070195 growth hormone receptor complex(GO:0070195)
0.2 1.0 GO:0020016 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.1 0.6 GO:1902560 GMP reductase complex(GO:1902560)
0.1 1.1 GO:0097255 R2TP complex(GO:0097255)
0.1 1.7 GO:0042589 zymogen granule membrane(GO:0042589)
0.1 0.4 GO:0097513 myosin II filament(GO:0097513)
0.1 2.0 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.3 GO:1990769 proximal neuron projection(GO:1990769)
0.1 2.2 GO:0042629 mast cell granule(GO:0042629)
0.0 0.7 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.5 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.3 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.2 GO:0036021 endolysosome lumen(GO:0036021)
0.0 0.1 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 2.2 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.6 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.1 GO:0089701 U2AF(GO:0089701)
0.0 0.1 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.1 GO:0043219 lateral loop(GO:0043219)
0.0 1.1 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 9.7 GO:0015629 actin cytoskeleton(GO:0015629)
0.0 2.4 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 4.4 GO:0035939 microsatellite binding(GO:0035939)
0.6 5.0 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.6 3.5 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.6 1.7 GO:0035375 zymogen binding(GO:0035375)
0.4 4.3 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.3 0.8 GO:0031696 alpha2-adrenergic receptor activity(GO:0004938) alpha-2C adrenergic receptor binding(GO:0031696)
0.2 0.7 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.2 0.8 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797)
0.1 1.2 GO:0016403 dimethylargininase activity(GO:0016403)
0.1 2.5 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.1 2.6 GO:0003680 AT DNA binding(GO:0003680)
0.1 0.6 GO:0003920 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.1 1.5 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 2.9 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.2 GO:0035514 DNA demethylase activity(GO:0035514)
0.1 2.3 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 0.9 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.3 GO:0070004 cysteine-type carboxypeptidase activity(GO:0016807) cysteine-type exopeptidase activity(GO:0070004)
0.0 0.3 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 1.7 GO:0004950 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950) CCR chemokine receptor binding(GO:0048020)
0.0 0.1 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.0 0.1 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.0 0.1 GO:0070363 mitochondrial light strand promoter sense binding(GO:0070363)
0.0 0.6 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.3 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0 0.7 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 1.1 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.2 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.3 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 0.6 GO:0048156 tau protein binding(GO:0048156)
0.0 0.9 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.1 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532) cupric ion binding(GO:1903135)
0.0 0.6 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.5 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.5 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.5 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.6 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.5 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.9 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 1.0 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.1 GO:0050733 RS domain binding(GO:0050733)
0.0 1.9 GO:0005518 collagen binding(GO:0005518)
0.0 1.4 GO:0051087 chaperone binding(GO:0051087)
0.0 0.8 GO:0001540 beta-amyloid binding(GO:0001540)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 5.0 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.1 4.3 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.1 5.5 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.1 2.8 ST GA12 PATHWAY G alpha 12 Pathway
0.0 2.6 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 3.5 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.2 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 2.3 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 2.8 PID E2F PATHWAY E2F transcription factor network
0.0 1.4 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.3 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.4 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 1.2 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.4 PID CDC42 REG PATHWAY Regulation of CDC42 activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 8.3 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.3 4.3 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 1.8 REACTOME SIGNALING BY NOTCH4 Genes involved in Signaling by NOTCH4
0.1 5.3 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 2.6 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 1.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.9 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 1.1 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.6 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.5 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 2.4 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.8 REACTOME PLATELET AGGREGATION PLUG FORMATION Genes involved in Platelet Aggregation (Plug Formation)
0.0 0.6 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.6 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.5 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.6 REACTOME KINESINS Genes involved in Kinesins
0.0 0.5 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.9 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.2 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.4 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse