Inflammatory response time course, HUVEC (Wada, 2009)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Download the whole report

Gene Symbol	Gene ID	Gene Info
RELA Links Ensembl NCBI GeneCards UniProt	ENSG00000173039.19	RELA

Gene	Promoter	Pearson corr. coef.	P-value	Plot
RELA	hg38_v1_chr11_-_65662780_65662928	0.93	2.0e-11	Click!

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Promoter	Score	Transcript	Gene	Gene Info
chr4_-_76023489 Show fit	78.16	ENST00000306602.3	CXCL10 Links Ensembl NCBI GeneCards UniProt Show fit	C-X-C motif chemokine ligand 10
chr6_-_31582415 Show fit	58.00	ENST00000429299.3 ENST00000446745.2	LTB Links Ensembl NCBI GeneCards UniProt Show fit	lymphotoxin beta
chr11_+_102317492 Show fit	54.56	ENST00000673846.1	BIRC3 Links Ensembl NCBI GeneCards UniProt Show fit	baculoviral IAP repeat containing 3
chr6_-_29559724 Show fit	46.65	ENST00000377050.5	UBD Links Ensembl NCBI GeneCards UniProt Show fit	ubiquitin D
chr6_+_137867241 Show fit	45.59	ENST00000612899.5 ENST00000420009.5	TNFAIP3 Links Ensembl NCBI GeneCards UniProt Show fit	TNF alpha induced protein 3
chr6_+_137867414 Show fit	44.98	ENST00000237289.8 ENST00000433680.1	TNFAIP3 Links Ensembl NCBI GeneCards UniProt Show fit	TNF alpha induced protein 3
chr19_+_45001430 Show fit	44.20	ENST00000625761.2 ENST00000505236.1 ENST00000221452.13	RELB Links Ensembl NCBI GeneCards UniProt Show fit	RELB proto-oncogene, NF-kB subunit
chr11_+_102317542 Show fit	40.40	ENST00000532808.5	BIRC3 Links Ensembl NCBI GeneCards UniProt Show fit	baculoviral IAP repeat containing 3
chr10_+_102394488 Show fit	39.71	ENST00000369966.8	NFKB2 Links Ensembl NCBI GeneCards UniProt Show fit	nuclear factor kappa B subunit 2
chr6_-_142946312 Show fit	39.64	ENST00000367604.6	HIVEP2 Links Ensembl NCBI GeneCards UniProt Show fit	HIVEP zinc finger 2
chr4_+_73836667 Show fit	39.46	ENST00000226317.10	CXCL6 Links Ensembl NCBI GeneCards UniProt Show fit	C-X-C motif chemokine ligand 6
chr11_+_102317450 Show fit	38.52	ENST00000615299.4 ENST00000527309.2 ENST00000526421.6 ENST00000263464.9	BIRC3 Links Ensembl NCBI GeneCards UniProt Show fit	baculoviral IAP repeat containing 3
chr2_+_227813834 Show fit	37.14	ENST00000358813.5 ENST00000409189.7	CCL20 Links Ensembl NCBI GeneCards UniProt Show fit	C-C motif chemokine ligand 20
chr19_+_4229502 Show fit	36.06	ENST00000221847.6	EBI3 Links Ensembl NCBI GeneCards UniProt Show fit	Epstein-Barr virus induced 3
chr4_+_102501298 Show fit	34.96	ENST00000394820.8 ENST00000226574.9 ENST00000511926.5 ENST00000507079.5	NFKB1 Links Ensembl NCBI GeneCards UniProt Show fit	nuclear factor kappa B subunit 1
chr19_+_10271093 Show fit	32.04	ENST00000423829.2 ENST00000588645.1 ENST00000264832.8	ICAM1 Links Ensembl NCBI GeneCards UniProt Show fit	intercellular adhesion molecule 1
chr1_+_100719734 Show fit	30.96	ENST00000370119.8 ENST00000294728.7 ENST00000347652.6 ENST00000370115.1	VCAM1 Links Ensembl NCBI GeneCards UniProt Show fit	vascular cell adhesion molecule 1
chr4_-_76036060 Show fit	28.64	ENST00000306621.8	CXCL11 Links Ensembl NCBI GeneCards UniProt Show fit	C-X-C motif chemokine ligand 11
chr1_+_109910485 Show fit	27.37	ENST00000525659.5	CSF1 Links Ensembl NCBI GeneCards UniProt Show fit	colony stimulating factor 1
chr17_+_42288429 Show fit	26.92	ENST00000676631.1 ENST00000677893.1	STAT5A Links Ensembl NCBI GeneCards UniProt Show fit	signal transducer and activator of transcription 5A
chr17_+_42288464 Show fit	26.63	ENST00000590726.7 ENST00000678903.1 ENST00000590949.6 ENST00000676585.1 ENST00000588868.5	STAT5A Links Ensembl NCBI GeneCards UniProt Show fit	signal transducer and activator of transcription 5A
chr4_+_73869385 Show fit	26.39	ENST00000395761.4	CXCL1 Links Ensembl NCBI GeneCards UniProt Show fit	C-X-C motif chemokine ligand 1
chr4_-_73998669 Show fit	25.19	ENST00000296027.5	CXCL5 Links Ensembl NCBI GeneCards UniProt Show fit	C-X-C motif chemokine ligand 5
chr14_+_103123452 Show fit	24.63	ENST00000558056.1 ENST00000560869.6	TNFAIP2 Links Ensembl NCBI GeneCards UniProt Show fit	TNF alpha induced protein 2
chr1_+_109910840 Show fit	24.51	ENST00000329608.11 ENST00000488198.5	CSF1 Links Ensembl NCBI GeneCards UniProt Show fit	colony stimulating factor 1
chr12_-_48865863 Show fit	23.94	ENST00000309739.6	RND1 Links Ensembl NCBI GeneCards UniProt Show fit	Rho family GTPase 1
chr4_-_74038681 Show fit	23.93	ENST00000296026.4	CXCL3 Links Ensembl NCBI GeneCards UniProt Show fit	C-X-C motif chemokine ligand 3
chr5_-_151080978 Show fit	23.57	ENST00000520931.5 ENST00000521591.6 ENST00000520695.5 ENST00000610535.5 ENST00000518977.5 ENST00000389378.6 ENST00000610874.4	TNIP1 Links Ensembl NCBI GeneCards UniProt Show fit	TNFAIP3 interacting protein 1
chr15_+_67138001 Show fit	22.82	ENST00000439724.7	SMAD3 Links Ensembl NCBI GeneCards UniProt Show fit	SMAD family member 3
chr12_-_9760893 Show fit	22.57	ENST00000228434.7 ENST00000536709.1	CD69 Links Ensembl NCBI GeneCards UniProt Show fit	CD69 molecule
chr5_-_151087131 Show fit	21.35	ENST00000315050.11 ENST00000523338.5 ENST00000522100.5	TNIP1 Links Ensembl NCBI GeneCards UniProt Show fit	TNFAIP3 interacting protein 1
chr12_-_57110284 Show fit	21.27	ENST00000543873.6 ENST00000554663.5 ENST00000557635.5	STAT6 Links Ensembl NCBI GeneCards UniProt Show fit	signal transducer and activator of transcription 6
chr6_+_144150492 Show fit	21.07	ENST00000367568.5	STX11 Links Ensembl NCBI GeneCards UniProt Show fit	syntaxin 11
chr2_+_236569817 Show fit	20.91	ENST00000272928.4	ACKR3 Links Ensembl NCBI GeneCards UniProt Show fit	atypical chemokine receptor 3
chr1_-_7940825 Show fit	20.88	ENST00000377507.8	TNFRSF9 Links Ensembl NCBI GeneCards UniProt Show fit	TNF receptor superfamily member 9
chr10_+_102395693 Show fit	20.52	ENST00000652277.1 ENST00000189444.11 ENST00000661543.1	NFKB2 Links Ensembl NCBI GeneCards UniProt Show fit	nuclear factor kappa B subunit 2
chr5_+_10564064 Show fit	20.24	ENST00000296657.7	ANKRD33B Links Ensembl NCBI GeneCards UniProt Show fit	ankyrin repeat domain 33B
chr4_-_74099187 Show fit	19.54	ENST00000508487.3	CXCL2 Links Ensembl NCBI GeneCards UniProt Show fit	C-X-C motif chemokine ligand 2
chr16_+_50742110 Show fit	19.29	ENST00000566679.6 ENST00000564634.5 ENST00000398568.6	CYLD Links Ensembl NCBI GeneCards UniProt Show fit	CYLD lysine 63 deubiquitinase
chr16_+_50742037 Show fit	19.27	ENST00000569418.5	CYLD Links Ensembl NCBI GeneCards UniProt Show fit	CYLD lysine 63 deubiquitinase
chr6_-_32853618 Show fit	19.09	ENST00000354258.5	TAP1 Links Ensembl NCBI GeneCards UniProt Show fit	transporter 1, ATP binding cassette subfamily B member
chr6_-_32853813 Show fit	18.86	ENST00000643049.2	TAP1 Links Ensembl NCBI GeneCards UniProt Show fit	transporter 1, ATP binding cassette subfamily B member
chr14_-_35404650 Show fit	18.77	ENST00000553342.1 ENST00000557140.5 ENST00000216797.10	NFKBIA Links Ensembl NCBI GeneCards UniProt Show fit	NFKB inhibitor alpha
chr11_-_128522264 Show fit	18.71	ENST00000531611.5	ETS1 Links Ensembl NCBI GeneCards UniProt Show fit	ETS proto-oncogene 1, transcription factor
chr11_-_128522189 Show fit	18.14	ENST00000526145.6	ETS1 Links Ensembl NCBI GeneCards UniProt Show fit	ETS proto-oncogene 1, transcription factor
chr3_+_53161120 Show fit	17.84	ENST00000394729.6 ENST00000330452.8 ENST00000652449.1	PRKCD Links Ensembl NCBI GeneCards UniProt Show fit	protein kinase C delta
chr3_+_53161241 Show fit	17.34	ENST00000477794.2 ENST00000650739.1	PRKCD Links Ensembl NCBI GeneCards UniProt Show fit	protein kinase C delta
chr12_+_77830886 Show fit	15.99	ENST00000397909.7 ENST00000549464.5	NAV3 Links Ensembl NCBI GeneCards UniProt Show fit	neuron navigator 3
chr1_-_94541746 Show fit	15.66	ENST00000334047.12	F3 Links Ensembl NCBI GeneCards UniProt Show fit	coagulation factor III, tissue factor
chr1_-_94541636 Show fit	15.65	ENST00000370207.4	F3 Links Ensembl NCBI GeneCards UniProt Show fit	coagulation factor III, tissue factor
chr16_+_50742059 Show fit	15.51	ENST00000311559.13 ENST00000564326.5 ENST00000566206.5 ENST00000427738.8	CYLD Links Ensembl NCBI GeneCards UniProt Show fit	CYLD lysine 63 deubiquitinase
chr2_-_162318475 Show fit	14.69	ENST00000648433.1	IFIH1 Links Ensembl NCBI GeneCards UniProt Show fit	interferon induced with helicase C domain 1
chr4_-_119628791 Show fit	14.60	ENST00000354960.8	PDE5A Links Ensembl NCBI GeneCards UniProt Show fit	phosphodiesterase 5A
chr11_+_122655712 Show fit	14.43	ENST00000284273.6	UBASH3B Links Ensembl NCBI GeneCards UniProt Show fit	ubiquitin associated and SH3 domain containing B
chr11_-_8810635 Show fit	14.39	ENST00000527510.5 ENST00000528527.5 ENST00000313726.11 ENST00000528523.5	DENND2B Links Ensembl NCBI GeneCards UniProt Show fit	DENN domain containing 2B
chr9_-_133479075 Show fit	13.60	ENST00000414172.1 ENST00000371897.8 ENST00000371899.9	SLC2A6 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 2 member 6
chr11_-_128522285 Show fit	13.25	ENST00000319397.6 ENST00000535549.5	ETS1 Links Ensembl NCBI GeneCards UniProt Show fit	ETS proto-oncogene 1, transcription factor
chr19_-_4338786 Show fit	13.11	ENST00000601482.1 ENST00000600324.5 ENST00000594605.6	STAP2 Links Ensembl NCBI GeneCards UniProt Show fit	signal transducing adaptor family member 2
chr4_-_119628007 Show fit	13.03	ENST00000420633.1 ENST00000394439.5	PDE5A Links Ensembl NCBI GeneCards UniProt Show fit	phosphodiesterase 5A
chr19_-_47231191 Show fit	12.90	ENST00000439096.3	BBC3 Links Ensembl NCBI GeneCards UniProt Show fit	BCL2 binding component 3
chr7_-_22356914 Show fit	12.83	ENST00000344041.10	RAPGEF5 Links Ensembl NCBI GeneCards UniProt Show fit	Rap guanine nucleotide exchange factor 5
chr8_+_85245451 Show fit	12.03	ENST00000321764.4	CA13 Links Ensembl NCBI GeneCards UniProt Show fit	carbonic anhydrase 13
chr10_+_30434176 Show fit	11.92	ENST00000263056.6 ENST00000375322.2	MAP3K8 Links Ensembl NCBI GeneCards UniProt Show fit	mitogen-activated protein kinase kinase kinase 8
chr10_+_30434021 Show fit	11.49	ENST00000542547.5	MAP3K8 Links Ensembl NCBI GeneCards UniProt Show fit	mitogen-activated protein kinase kinase kinase 8
chr11_-_72781858 Show fit	11.40	ENST00000537947.5	STARD10 Links Ensembl NCBI GeneCards UniProt Show fit	StAR related lipid transfer domain containing 10
chr21_+_33403466 Show fit	11.33	ENST00000405436.5	IFNGR2 Links Ensembl NCBI GeneCards UniProt Show fit	interferon gamma receptor 2
chr21_+_33403391 Show fit	11.16	ENST00000290219.11 ENST00000381995.5	IFNGR2 Links Ensembl NCBI GeneCards UniProt Show fit	interferon gamma receptor 2
chr2_+_161136901 Show fit	10.81	ENST00000259075.6 ENST00000432002.5	TANK Links Ensembl NCBI GeneCards UniProt Show fit	TRAF family member associated NFKB activator
chr3_+_101827982 Show fit	10.54	ENST00000461724.5 ENST00000483180.5 ENST00000394054.6	NFKBIZ Links Ensembl NCBI GeneCards UniProt Show fit	NFKB inhibitor zeta
chr1_-_209652329 Show fit	10.28	ENST00000367030.7 ENST00000356082.9	LAMB3 Links Ensembl NCBI GeneCards UniProt Show fit	laminin subunit beta 3
chr17_-_63699730 Show fit	10.26	ENST00000578061.5	LIMD2 Links Ensembl NCBI GeneCards UniProt Show fit	LIM domain containing 2
chr5_+_31639104 Show fit	10.23	ENST00000438447.2	PDZD2 Links Ensembl NCBI GeneCards UniProt Show fit	PDZ domain containing 2
chr22_-_19525369 Show fit	10.04	ENST00000403084.1 ENST00000413119.2	CLDN5 Links Ensembl NCBI GeneCards UniProt Show fit	claudin 5
chr6_+_29723340 Show fit	9.77	ENST00000334668.8	HLA-F Links Ensembl NCBI GeneCards UniProt Show fit	major histocompatibility complex, class I, F
chr7_-_99144053 Show fit	9.40	ENST00000361125.1 ENST00000361368.7	SMURF1 Links Ensembl NCBI GeneCards UniProt Show fit	SMAD specific E3 ubiquitin protein ligase 1
chr14_+_73237493 Show fit	9.31	ENST00000340738.9 ENST00000644200.2	PAPLN Links Ensembl NCBI GeneCards UniProt Show fit	papilin, proteoglycan like sulfated glycoprotein
chr9_-_114806031 Show fit	9.30	ENST00000374045.5	TNFSF15 Links Ensembl NCBI GeneCards UniProt Show fit	TNF superfamily member 15
chr11_-_72781833 Show fit	9.22	ENST00000535054.1 ENST00000545082.5	STARD10 Links Ensembl NCBI GeneCards UniProt Show fit	StAR related lipid transfer domain containing 10
chr17_-_35880350 Show fit	9.21	ENST00000605140.6 ENST00000651122.1 ENST00000603197.6	CCL5 Links Ensembl NCBI GeneCards UniProt Show fit	C-C motif chemokine ligand 5
chr4_-_184474518 Show fit	9.16	ENST00000393593.8	IRF2 Links Ensembl NCBI GeneCards UniProt Show fit	interferon regulatory factor 2
chr17_+_21288029 Show fit	8.99	ENST00000526076.6 ENST00000361818.9 ENST00000316920.10	MAP2K3 Links Ensembl NCBI GeneCards UniProt Show fit	mitogen-activated protein kinase kinase 3
chr6_+_29723421 Show fit	8.96	ENST00000259951.12 ENST00000434407.6	HLA-F Links Ensembl NCBI GeneCards UniProt Show fit	major histocompatibility complex, class I, F
chr16_+_50696999 Show fit	8.85	ENST00000300589.6	NOD2 Links Ensembl NCBI GeneCards UniProt Show fit	nucleotide binding oligomerization domain containing 2
chr2_-_162318613 Show fit	8.77	ENST00000649979.2 ENST00000421365.2	IFIH1 Links Ensembl NCBI GeneCards UniProt Show fit	interferon induced with helicase C domain 1
chr20_-_45348414 Show fit	8.76	ENST00000372733.3	SDC4 Links Ensembl NCBI GeneCards UniProt Show fit	syndecan 4
chr14_+_102777461 Show fit	8.48	ENST00000560371.5 ENST00000347662.8	TRAF3 Links Ensembl NCBI GeneCards UniProt Show fit	TNF receptor associated factor 3
chr13_+_97222296 Show fit	8.32	ENST00000343600.8 ENST00000376673.7 ENST00000679496.1 ENST00000345429.10	MBNL2 Links Ensembl NCBI GeneCards UniProt Show fit	muscleblind like splicing regulator 2
chr2_+_68467544 Show fit	8.11	ENST00000303795.9	APLF Links Ensembl NCBI GeneCards UniProt Show fit	aprataxin and PNKP like factor
chr14_+_102777555 Show fit	8.01	ENST00000539721.5 ENST00000560463.5	TRAF3 Links Ensembl NCBI GeneCards UniProt Show fit	TNF receptor associated factor 3
chr10_+_13100075 Show fit	7.95	ENST00000378747.8 ENST00000378757.6 ENST00000378752.7 ENST00000378748.7	OPTN Links Ensembl NCBI GeneCards UniProt Show fit	optineurin
chr4_-_121164314 Show fit	7.84	ENST00000057513.8	TNIP3 Links Ensembl NCBI GeneCards UniProt Show fit	TNFAIP3 interacting protein 3
chr1_+_206470463 Show fit	7.84	ENST00000581977.7 ENST00000578328.6 ENST00000584998.5 ENST00000579827.6	IKBKE Links Ensembl NCBI GeneCards UniProt Show fit	inhibitor of nuclear factor kappa B kinase subunit epsilon
chr10_+_13099585 Show fit	7.81	ENST00000378764.6	OPTN Links Ensembl NCBI GeneCards UniProt Show fit	optineurin
chr20_+_46118300 Show fit	7.66	ENST00000372285.8 ENST00000372276.7	CD40 Links Ensembl NCBI GeneCards UniProt Show fit	CD40 molecule
chr11_-_75351686 Show fit	7.62	ENST00000360025.7	ARRB1 Links Ensembl NCBI GeneCards UniProt Show fit	arrestin beta 1
chr14_+_102777433 Show fit	7.57	ENST00000392745.8	TRAF3 Links Ensembl NCBI GeneCards UniProt Show fit	TNF receptor associated factor 3
chr2_-_96505345 Show fit	7.50	ENST00000310865.7 ENST00000451794.6	NEURL3 Links Ensembl NCBI GeneCards UniProt Show fit	neuralized E3 ubiquitin protein ligase 3
chr1_-_64966284 Show fit	7.38	ENST00000671929.1 ENST00000673046.1 ENST00000672247.1	JAK1 Links Ensembl NCBI GeneCards UniProt Show fit	Janus kinase 1
chr14_+_22515623 Show fit	7.37	ENST00000390509.1	TRAJ28 Links Ensembl NCBI GeneCards UniProt Show fit	T cell receptor alpha joining 28
chr11_-_57426745 Show fit	7.22	ENST00000529554.5	SLC43A3 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 43 member 3
chr4_+_4859658 Show fit	7.18	ENST00000382723.5	MSX1 Links Ensembl NCBI GeneCards UniProt Show fit	msh homeobox 1
chr19_-_17847962 Show fit	7.06	ENST00000458235.7 ENST00000534444.1	JAK3 Links Ensembl NCBI GeneCards UniProt Show fit	Janus kinase 3
chr2_+_161160420 Show fit	6.92	ENST00000392749.7 ENST00000405852.5	TANK Links Ensembl NCBI GeneCards UniProt Show fit	TRAF family member associated NFKB activator
chr20_+_46118277 Show fit	6.91	ENST00000620709.4	CD40 Links Ensembl NCBI GeneCards UniProt Show fit	CD40 molecule
chr9_+_100429511 Show fit	6.84	ENST00000613183.1	MSANTD3 Links Ensembl NCBI GeneCards UniProt Show fit	Myb/SANT DNA binding domain containing 3
chr14_+_93430927 Show fit	6.78	ENST00000393151.6	UNC79 Links Ensembl NCBI GeneCards UniProt Show fit	unc-79 homolog, NALCN channel complex subunit
chr1_-_209651291 Show fit	6.77	ENST00000391911.5 ENST00000415782.1	LAMB3 Links Ensembl NCBI GeneCards UniProt Show fit	laminin subunit beta 3
chr2_+_96537254 Show fit	6.49	ENST00000454558.2	ARID5A Links Ensembl NCBI GeneCards UniProt Show fit	AT-rich interaction domain 5A
chr1_+_100352451 Show fit	6.26	ENST00000361544.11 ENST00000370124.8 ENST00000336454.5	CDC14A Links Ensembl NCBI GeneCards UniProt Show fit	cell division cycle 14A
chr2_+_96536743 Show fit	6.25	ENST00000673792.1 ENST00000357485.8	ARID5A Links Ensembl NCBI GeneCards UniProt Show fit	AT-rich interaction domain 5A
chr7_+_143381561 Show fit	6.19	ENST00000354434.8	ZYX Links Ensembl NCBI GeneCards UniProt Show fit	zyxin
chr1_-_64966488 Show fit	6.14	ENST00000342505.5 ENST00000673254.1	JAK1 Links Ensembl NCBI GeneCards UniProt Show fit	Janus kinase 1
chr19_+_38899680 Show fit	6.02	ENST00000576510.5 ENST00000392079.7	NFKBIB Links Ensembl NCBI GeneCards UniProt Show fit	NFKB inhibitor beta
chr7_+_143381286 Show fit	5.87	ENST00000449630.5 ENST00000322764.10 ENST00000457235.5	ZYX Links Ensembl NCBI GeneCards UniProt Show fit	zyxin
chr6_+_106086316 Show fit	5.82	ENST00000369091.6 ENST00000369096.9	PRDM1 Links Ensembl NCBI GeneCards UniProt Show fit	PR/SET domain 1
chr17_+_7351889 Show fit	5.56	ENST00000576980.2	KCTD11 Links Ensembl NCBI GeneCards UniProt Show fit	potassium channel tetramerization domain containing 11
chr15_+_52019206 Show fit	5.47	ENST00000681888.1 ENST00000261845.7 ENST00000680066.1 ENST00000680777.1 ENST00000680652.1	MAPK6 Links Ensembl NCBI GeneCards UniProt Show fit	mitogen-activated protein kinase 6
chr17_+_7352142 Show fit	5.37	ENST00000333751.8	KCTD11 Links Ensembl NCBI GeneCards UniProt Show fit	potassium channel tetramerization domain containing 11
chr6_+_135181323 Show fit	5.30	ENST00000367814.8	MYB Links Ensembl NCBI GeneCards UniProt Show fit	MYB proto-oncogene, transcription factor
chr1_+_109910892 Show fit	5.28	ENST00000369802.7 ENST00000420111.6	CSF1 Links Ensembl NCBI GeneCards UniProt Show fit	colony stimulating factor 1
chr19_+_38899946 Show fit	5.25	ENST00000572515.5 ENST00000313582.6 ENST00000575359.5	NFKBIB Links Ensembl NCBI GeneCards UniProt Show fit	NFKB inhibitor beta
chr16_-_57284654 Show fit	5.22	ENST00000613167.4 ENST00000219207.10 ENST00000569059.5	PLLP Links Ensembl NCBI GeneCards UniProt Show fit	plasmolipin
chr15_-_75451543 Show fit	5.16	ENST00000394949.8	SIN3A Links Ensembl NCBI GeneCards UniProt Show fit	SIN3 transcription regulator family member A
chr9_-_32526185 Show fit	4.98	ENST00000379883.3 ENST00000379868.6 ENST00000679859.1	DDX58 Links Ensembl NCBI GeneCards UniProt Show fit	DExD/H-box helicase 58
chr2_+_64454506 Show fit	4.93	ENST00000409537.2	LGALSL Links Ensembl NCBI GeneCards UniProt Show fit	galectin like
chr11_-_75351609 Show fit	4.92	ENST00000420843.7	ARRB1 Links Ensembl NCBI GeneCards UniProt Show fit	arrestin beta 1
chr14_+_93430853 Show fit	4.79	ENST00000553484.5	UNC79 Links Ensembl NCBI GeneCards UniProt Show fit	unc-79 homolog, NALCN channel complex subunit
chr11_+_118607598 Show fit	4.70	ENST00000600882.6 ENST00000356063.9	PHLDB1 Links Ensembl NCBI GeneCards UniProt Show fit	pleckstrin homology like domain family B member 1
chr15_-_75451650 Show fit	4.64	ENST00000567289.5 ENST00000394947.8 ENST00000565264.1	SIN3A Links Ensembl NCBI GeneCards UniProt Show fit	SIN3 transcription regulator family member A
chr11_-_3840942 Show fit	4.49	ENST00000351018.5	RHOG Links Ensembl NCBI GeneCards UniProt Show fit	ras homolog family member G
chr6_+_135181268 Show fit	4.46	ENST00000341911.10 ENST00000442647.7 ENST00000618728.4 ENST00000316528.12 ENST00000616088.4	MYB Links Ensembl NCBI GeneCards UniProt Show fit	MYB proto-oncogene, transcription factor
chr8_-_12755457 Show fit	4.45	ENST00000398246.8	LONRF1 Links Ensembl NCBI GeneCards UniProt Show fit	LON peptidase N-terminal domain and ring finger 1
chr1_+_100352925 Show fit	4.40	ENST00000644813.1	CDC14A Links Ensembl NCBI GeneCards UniProt Show fit	cell division cycle 14A
chr1_-_159925496 Show fit	4.35	ENST00000368097.9	TAGLN2 Links Ensembl NCBI GeneCards UniProt Show fit	transgelin 2
chr15_+_44427793 Show fit	4.32	ENST00000558966.5 ENST00000559793.5 ENST00000558968.1	CTDSPL2 Links Ensembl NCBI GeneCards UniProt Show fit	CTD small phosphatase like 2
chr4_-_102828048 Show fit	4.28	ENST00000508249.1	UBE2D3 Links Ensembl NCBI GeneCards UniProt Show fit	ubiquitin conjugating enzyme E2 D3
chr1_+_44405164 Show fit	4.25	ENST00000355387.6	RNF220 Links Ensembl NCBI GeneCards UniProt Show fit	ring finger protein 220
chr5_+_134648772 Show fit	4.23	ENST00000398844.7 ENST00000322887.8	SEC24A Links Ensembl NCBI GeneCards UniProt Show fit	SEC24 homolog A, COPII coat complex component
chr5_-_132777344 Show fit	4.12	ENST00000378706.5	SEPTIN8 Links Ensembl NCBI GeneCards UniProt Show fit	septin 8
chr2_-_208163588 Show fit	4.08	ENST00000304502.5	CRYGA Links Ensembl NCBI GeneCards UniProt Show fit	crystallin gamma A
chr2_-_135985568 Show fit	4.00	ENST00000264161.9	DARS1 Links Ensembl NCBI GeneCards UniProt Show fit	aspartyl-tRNA synthetase 1
chr12_+_49367364 Show fit	3.89	ENST00000549298.5	SPATS2 Links Ensembl NCBI GeneCards UniProt Show fit	spermatogenesis associated serine rich 2
chr19_+_41219235 Show fit	3.88	ENST00000359092.7	AXL Links Ensembl NCBI GeneCards UniProt Show fit	AXL receptor tyrosine kinase
chr3_+_157436842 Show fit	3.86	ENST00000295927.4	PTX3 Links Ensembl NCBI GeneCards UniProt Show fit	pentraxin 3
chr11_+_65525413 Show fit	3.81	ENST00000527009.5	SCYL1 Links Ensembl NCBI GeneCards UniProt Show fit	SCY1 like pseudokinase 1
chr2_+_207529731 Show fit	3.74	ENST00000430624.5	CREB1 Links Ensembl NCBI GeneCards UniProt Show fit	cAMP responsive element binding protein 1
chr16_-_66925526 Show fit	3.74	ENST00000299759.11 ENST00000420652.5	RRAD Links Ensembl NCBI GeneCards UniProt Show fit	RRAD, Ras related glycolysis inhibitor and calcium channel regulator
chr1_+_44405247 Show fit	3.68	ENST00000361799.7 ENST00000372247.6	RNF220 Links Ensembl NCBI GeneCards UniProt Show fit	ring finger protein 220
chr17_-_7687427 Show fit	3.66	ENST00000514944.5 ENST00000503591.1 ENST00000610292.4 ENST00000420246.6 ENST00000455263.6 ENST00000610538.4 ENST00000622645.4 ENST00000445888.6 ENST00000619485.4 ENST00000509690.5 ENST00000604348.5 ENST00000269305.9 ENST00000620739.4	TP53 Links Ensembl NCBI GeneCards UniProt Show fit	tumor protein p53
chr20_+_18507884 Show fit	3.57	ENST00000643747.1 ENST00000474619.1 ENST00000645851.1 ENST00000650089.1 ENST00000377465.6	SEC23B Links Ensembl NCBI GeneCards UniProt Show fit	SEC23 homolog B, COPII coat complex component
chr20_-_4815100 Show fit	3.42	ENST00000379376.2	RASSF2 Links Ensembl NCBI GeneCards UniProt Show fit	Ras association domain family member 2
chr5_-_132777215 Show fit	3.40	ENST00000458488.2	SEPTIN8 Links Ensembl NCBI GeneCards UniProt Show fit	septin 8
chrX_-_49043345 Show fit	3.33	ENST00000315869.8	TFE3 Links Ensembl NCBI GeneCards UniProt Show fit	transcription factor binding to IGHM enhancer 3
chr5_-_132777371 Show fit	3.29	ENST00000620483.4	SEPTIN8 Links Ensembl NCBI GeneCards UniProt Show fit	septin 8
chr15_+_41774459 Show fit	3.26	ENST00000457542.7 ENST00000456763.6	MAPKBP1 Links Ensembl NCBI GeneCards UniProt Show fit	mitogen-activated protein kinase binding protein 1
chr20_+_18507520 Show fit	3.23	ENST00000336714.8 ENST00000646240.1 ENST00000450074.6 ENST00000262544.6	SEC23B Links Ensembl NCBI GeneCards UniProt Show fit	SEC23 homolog B, COPII coat complex component
chr10_+_84328625 Show fit	3.16	ENST00000224756.12	CCSER2 Links Ensembl NCBI GeneCards UniProt Show fit	coiled-coil serine rich protein 2
chr17_+_17782108 Show fit	3.15	ENST00000395774.1	RAI1 Links Ensembl NCBI GeneCards UniProt Show fit	retinoic acid induced 1
chr12_+_53268289 Show fit	3.13	ENST00000257934.9	ESPL1 Links Ensembl NCBI GeneCards UniProt Show fit	extra spindle pole bodies like 1, separase
chr18_+_34710307 Show fit	3.13	ENST00000679796.1	DTNA Links Ensembl NCBI GeneCards UniProt Show fit	dystrobrevin alpha
chr18_-_12884151 Show fit	3.12	ENST00000591115.5 ENST00000309660.10 ENST00000353319.8 ENST00000327283.7	PTPN2 Links Ensembl NCBI GeneCards UniProt Show fit	protein tyrosine phosphatase non-receptor type 2
chr5_-_132777404 Show fit	3.12	ENST00000296873.11	SEPTIN8 Links Ensembl NCBI GeneCards UniProt Show fit	septin 8
chr14_-_88554898 Show fit	3.08	ENST00000556564.6	PTPN21 Links Ensembl NCBI GeneCards UniProt Show fit	protein tyrosine phosphatase non-receptor type 21
chr3_-_138834752 Show fit	3.07	ENST00000477593.5 ENST00000483968.5	PIK3CB Links Ensembl NCBI GeneCards UniProt Show fit	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
chr12_+_49367440 Show fit	3.06	ENST00000552918.6 ENST00000553127.5 ENST00000321898.10	SPATS2 Links Ensembl NCBI GeneCards UniProt Show fit	spermatogenesis associated serine rich 2
chr11_+_65525067 Show fit	3.03	ENST00000525364.5 ENST00000270176.10 ENST00000420247.6 ENST00000533862.5 ENST00000524944.5	SCYL1 Links Ensembl NCBI GeneCards UniProt Show fit	SCY1 like pseudokinase 1
chr4_-_102827723 Show fit	2.90	ENST00000349311.12	UBE2D3 Links Ensembl NCBI GeneCards UniProt Show fit	ubiquitin conjugating enzyme E2 D3
chr22_-_37984534 Show fit	2.89	ENST00000396884.8	SOX10 Links Ensembl NCBI GeneCards UniProt Show fit	SRY-box transcription factor 10
chr20_+_35772003 Show fit	2.88	ENST00000374012.8 ENST00000339089.10 ENST00000374000.8	PHF20 Links Ensembl NCBI GeneCards UniProt Show fit	PHD finger protein 20
chr21_-_41953997 Show fit	2.87	ENST00000380486.4	C2CD2 Links Ensembl NCBI GeneCards UniProt Show fit	C2 calcium dependent domain containing 2
chr14_-_50831046 Show fit	2.81	ENST00000476352.5 ENST00000324330.13 ENST00000382041.7 ENST00000453401.6 ENST00000530997.7	NIN Links Ensembl NCBI GeneCards UniProt Show fit	ninein
chr3_-_58577367 Show fit	2.79	ENST00000464064.5 ENST00000360997.7	FAM107A Links Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 107 member A
chr10_+_12349533 Show fit	2.77	ENST00000619168.5	CAMK1D Links Ensembl NCBI GeneCards UniProt Show fit	calcium/calmodulin dependent protein kinase ID
chr17_+_16415553 Show fit	2.77	ENST00000338560.12	TRPV2 Links Ensembl NCBI GeneCards UniProt Show fit	transient receptor potential cation channel subfamily V member 2
chr12_-_48105808 Show fit	2.70	ENST00000448372.5	SENP1 Links Ensembl NCBI GeneCards UniProt Show fit	SUMO specific peptidase 1
chr22_-_27919199 Show fit	2.70	ENST00000634017.1 ENST00000436663.1 ENST00000320996.14 ENST00000335272.10 ENST00000455418.7	PITPNB Links Ensembl NCBI GeneCards UniProt Show fit	phosphatidylinositol transfer protein beta
chr10_-_43408787 Show fit	2.68	ENST00000356053.7	HNRNPF Links Ensembl NCBI GeneCards UniProt Show fit	heterogeneous nuclear ribonucleoprotein F
chr15_+_44427591 Show fit	2.66	ENST00000558791.5 ENST00000260327.9	CTDSPL2 Links Ensembl NCBI GeneCards UniProt Show fit	CTD small phosphatase like 2
chr1_+_151198536 Show fit	2.64	ENST00000349792.9 ENST00000409426.5 ENST00000368888.9 ENST00000441902.6 ENST00000368890.8 ENST00000424999.1	PIP5K1A Links Ensembl NCBI GeneCards UniProt Show fit	phosphatidylinositol-4-phosphate 5-kinase type 1 alpha
chr14_-_50830479 Show fit	2.62	ENST00000382043.8	NIN Links Ensembl NCBI GeneCards UniProt Show fit	ninein
chr1_-_1891056 Show fit	2.59	ENST00000378609.9 ENST00000610897.4 ENST00000615252.4	GNB1 Links Ensembl NCBI GeneCards UniProt Show fit	G protein subunit beta 1
chr1_-_155978144 Show fit	2.58	ENST00000313695.11 ENST00000497907.5	ARHGEF2 Links Ensembl NCBI GeneCards UniProt Show fit	Rho/Rac guanine nucleotide exchange factor 2
chr4_-_76007501 Show fit	2.54	ENST00000264888.6	CXCL9 Links Ensembl NCBI GeneCards UniProt Show fit	C-X-C motif chemokine ligand 9
chr17_+_78168565 Show fit	2.52	ENST00000225777.8 ENST00000585591.5 ENST00000589711.1 ENST00000588282.5 ENST00000589168.1	SYNGR2 Links Ensembl NCBI GeneCards UniProt Show fit	synaptogyrin 2
chr5_-_59356962 Show fit	2.50	ENST00000405755.6	PDE4D Links Ensembl NCBI GeneCards UniProt Show fit	phosphodiesterase 4D
chr19_+_51225059 Show fit	2.48	ENST00000436584.6 ENST00000421133.6 ENST00000262262.5 ENST00000391796.7	CD33 Links Ensembl NCBI GeneCards UniProt Show fit	CD33 molecule
chr5_-_159099909 Show fit	2.43	ENST00000313708.11	EBF1 Links Ensembl NCBI GeneCards UniProt Show fit	EBF transcription factor 1
chr6_-_136525961 Show fit	2.42	ENST00000438100.6	MAP7 Links Ensembl NCBI GeneCards UniProt Show fit	microtubule associated protein 7
chr13_-_37869723 Show fit	2.39	ENST00000426868.6 ENST00000379705.8 ENST00000338947.9 ENST00000355779.6 ENST00000358477.6 ENST00000379673.2	TRPC4 Links Ensembl NCBI GeneCards UniProt Show fit	transient receptor potential cation channel subfamily C member 4
chr22_-_37244417 Show fit	2.39	ENST00000405484.5 ENST00000441619.5 ENST00000406508.5	RAC2 Links Ensembl NCBI GeneCards UniProt Show fit	Rac family small GTPase 2
chr10_+_120457197 Show fit	2.38	ENST00000398250.6	PLPP4 Links Ensembl NCBI GeneCards UniProt Show fit	phospholipid phosphatase 4
chr11_+_75240761 Show fit	2.34	ENST00000562197.3	TPBGL Links Ensembl NCBI GeneCards UniProt Show fit	trophoblast glycoprotein like
chr12_+_57216779 Show fit	2.33	ENST00000349394.6	NXPH4 Links Ensembl NCBI GeneCards UniProt Show fit	neurexophilin 4
chr11_-_57530714 Show fit	2.32	ENST00000525158.1 ENST00000257245.9 ENST00000525587.1	TIMM10 Links Ensembl NCBI GeneCards UniProt Show fit	translocase of inner mitochondrial membrane 10
chr4_+_139301478 Show fit	2.29	ENST00000296543.10 ENST00000398947.1	NAA15 Links Ensembl NCBI GeneCards UniProt Show fit	N-alpha-acetyltransferase 15, NatA auxiliary subunit
chr12_-_48106042 Show fit	2.24	ENST00000551798.1 ENST00000549518.6	SENP1 Links Ensembl NCBI GeneCards UniProt Show fit	SUMO specific peptidase 1
chr11_+_94768331 Show fit	2.23	ENST00000317829.12 ENST00000433060.3	AMOTL1 Links Ensembl NCBI GeneCards UniProt Show fit	angiomotin like 1
chr1_-_46198402 Show fit	2.21	ENST00000371984.8	POMGNT1 Links Ensembl NCBI GeneCards UniProt Show fit	protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)
chr12_-_6607397 Show fit	2.21	ENST00000645005.1 ENST00000646806.1	CHD4 Links Ensembl NCBI GeneCards UniProt Show fit	chromodomain helicase DNA binding protein 4
chr3_-_138834867 Show fit	2.19	ENST00000674063.1	PIK3CB Links Ensembl NCBI GeneCards UniProt Show fit	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
30.2	90.6	GO:0034147	regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429)
15.1	60.2	GO:0002268	follicular dendritic cell differentiation(GO:0002268)
15.0	44.9	GO:0044501	modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
14.3	57.2	GO:1902228	positive regulation of odontogenesis of dentin-containing tooth(GO:0042488) mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) positive regulation of microglial cell migration(GO:1904141)
13.5	54.1	GO:1990108	protein linear deubiquitination(GO:1990108)
12.6	37.9	GO:0046967	cytosol to ER transport(GO:0046967)
12.4	37.1	GO:0045362	regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
11.7	35.2	GO:2000752	regulation of phospholipid scramblase activity(GO:1900161) positive regulation of phospholipid scramblase activity(GO:1900163) regulation of glucosylceramide catabolic process(GO:2000752) positive regulation of glucosylceramide catabolic process(GO:2000753) regulation of sphingomyelin catabolic process(GO:2000754) positive regulation of sphingomyelin catabolic process(GO:2000755)
9.8	108.0	GO:0043950	positive regulation of cAMP-mediated signaling(GO:0043950)
9.5	133.5	GO:0070424	regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
9.4	18.8	GO:0070427	nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
9.0	63.0	GO:0022614	membrane to membrane docking(GO:0022614)
8.5	93.0	GO:0042090	interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
7.8	31.3	GO:0002541	activation of plasma proteins involved in acute inflammatory response(GO:0002541)
7.7	53.6	GO:0000255	allantoin metabolic process(GO:0000255)
5.8	46.6	GO:0070842	aggresome assembly(GO:0070842)
5.7	28.4	GO:0034343	type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
5.3	21.3	GO:0002296	T-helper 1 cell lineage commitment(GO:0002296)
5.0	50.1	GO:1904996	positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
4.4	17.7	GO:2000158	positive regulation of ubiquitin-specific protease activity(GO:2000158)
4.4	8.8	GO:1902523	positive regulation of protein K63-linked ubiquitination(GO:1902523)
3.9	132.9	GO:0090023	positive regulation of neutrophil chemotaxis(GO:0090023)
3.8	22.8	GO:0061767	negative regulation of lung blood pressure(GO:0061767)
3.6	14.6	GO:0033590	response to cobalamin(GO:0033590)
3.5	7.1	GO:0002730	regulation of dendritic cell cytokine production(GO:0002730)
3.5	24.6	GO:0060282	positive regulation of oocyte development(GO:0060282)
3.5	20.9	GO:2001180	negative regulation of interleukin-10 secretion(GO:2001180)
3.3	9.8	GO:1901675	negative regulation of histone H3-K27 acetylation(GO:1901675)
3.3	9.8	GO:1904899	regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
3.1	25.2	GO:0061734	parkin-mediated mitophagy in response to mitochondrial depolarization(GO:0061734)
2.3	23.3	GO:0008063	Toll signaling pathway(GO:0008063)
2.3	9.2	GO:0033634	positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
2.3	34.1	GO:0032688	negative regulation of interferon-beta production(GO:0032688)
2.3	36.1	GO:0045078	positive regulation of interferon-gamma biosynthetic process(GO:0045078)
2.1	6.3	GO:0090222	centrosome-templated microtubule nucleation(GO:0090222)
1.9	5.8	GO:0033082	regulation of extrathymic T cell differentiation(GO:0033082) sebum secreting cell proliferation(GO:1990654)
1.9	18.7	GO:0002480	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
1.8	3.7	GO:0097252	oligodendrocyte apoptotic process(GO:0097252)
1.8	7.2	GO:0035880	embryonic nail plate morphogenesis(GO:0035880) activation of meiosis(GO:0090427)
1.6	20.6	GO:0032782	bile acid secretion(GO:0032782)
1.6	12.5	GO:0042699	follicle-stimulating hormone signaling pathway(GO:0042699)
1.6	10.9	GO:0007406	negative regulation of neuroblast proliferation(GO:0007406)
1.5	24.6	GO:0051601	exocyst localization(GO:0051601)
1.5	3.0	GO:2000669	negative regulation of dendritic cell apoptotic process(GO:2000669)
1.5	8.8	GO:1903553	positive regulation of extracellular exosome assembly(GO:1903553)
1.4	12.3	GO:0038110	interleukin-2-mediated signaling pathway(GO:0038110)
1.3	23.9	GO:0016322	neuron remodeling(GO:0016322)
1.3	2.6	GO:0002876	positive regulation of chronic inflammatory response to antigenic stimulus(GO:0002876)
1.3	3.9	GO:1903015	regulation of exo-alpha-sialidase activity(GO:1903015)
1.1	10.0	GO:1903142	positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
1.1	5.3	GO:0033031	positive regulation of neutrophil apoptotic process(GO:0033031)
1.0	9.0	GO:0035897	proteolysis in other organism(GO:0035897)
0.9	3.7	GO:1901842	negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.8	8.1	GO:0051106	positive regulation of DNA ligation(GO:0051106)
0.8	3.2	GO:0034670	chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.8	2.4	GO:1900169	regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.8	21.1	GO:0031629	synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.7	3.7	GO:0071802	negative regulation of podosome assembly(GO:0071802)
0.7	4.4	GO:1900425	negative regulation of defense response to bacterium(GO:1900425)
0.6	11.6	GO:0048149	behavioral response to ethanol(GO:0048149)
0.6	3.1	GO:0045875	negative regulation of sister chromatid cohesion(GO:0045875)
0.6	4.9	GO:0016926	protein desumoylation(GO:0016926)
0.6	17.1	GO:0031581	hemidesmosome assembly(GO:0031581)
0.6	14.4	GO:0090331	negative regulation of platelet aggregation(GO:0090331)
0.6	2.9	GO:0071393	cellular response to progesterone stimulus(GO:0071393)
0.6	9.4	GO:0051256	mitotic spindle midzone assembly(GO:0051256)
0.5	1.6	GO:0045357	interferon-beta biosynthetic process(GO:0045350) regulation of interferon-beta biosynthetic process(GO:0045357) positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.5	1.5	GO:1904616	regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616)
0.5	26.9	GO:0002756	MyD88-independent toll-like receptor signaling pathway(GO:0002756)
0.5	15.2	GO:0060334	regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.4	9.3	GO:0007250	activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.4	4.2	GO:2000189	positive regulation of cholesterol homeostasis(GO:2000189)
0.4	5.2	GO:0001766	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.4	22.4	GO:1902230	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.4	4.2	GO:0072553	terminal button organization(GO:0072553)
0.4	13.6	GO:0035428	hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.4	1.4	GO:0060671	epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.3	1.7	GO:0097039	protein linear polyubiquitination(GO:0097039)
0.3	12.9	GO:0090200	positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.3	3.5	GO:0002191	cap-dependent translational initiation(GO:0002191)
0.3	3.4	GO:1901223	negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.3	0.9	GO:0016340	calcium-dependent cell-matrix adhesion(GO:0016340)
0.3	0.9	GO:0031938	cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245) regulation of chromatin silencing at telomere(GO:0031938)
0.3	5.0	GO:0006782	protoporphyrinogen IX biosynthetic process(GO:0006782)
0.3	2.3	GO:0045039	protein import into mitochondrial inner membrane(GO:0045039)
0.3	2.3	GO:0017196	N-terminal peptidyl-methionine acetylation(GO:0017196)
0.3	2.5	GO:0086024	adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.2	2.4	GO:0014051	gamma-aminobutyric acid secretion(GO:0014051)
0.2	1.1	GO:1902766	skeletal muscle satellite cell migration(GO:1902766)
0.2	0.6	GO:0071109	superior temporal gyrus development(GO:0071109)
0.2	7.0	GO:0046827	positive regulation of protein export from nucleus(GO:0046827)
0.2	1.4	GO:0032971	regulation of muscle filament sliding(GO:0032971)
0.2	12.0	GO:0006730	one-carbon metabolic process(GO:0006730)
0.2	3.7	GO:0003334	keratinocyte development(GO:0003334)
0.2	3.1	GO:0032486	Rap protein signal transduction(GO:0032486)
0.2	3.0	GO:1904259	regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.2	17.9	GO:0035690	cellular response to drug(GO:0035690)
0.2	0.7	GO:0048200	COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.2	0.3	GO:0038158	granulocyte colony-stimulating factor signaling pathway(GO:0038158)
0.1	1.2	GO:2000074	regulation of type B pancreatic cell development(GO:2000074) negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.1	2.6	GO:0070208	protein heterotrimerization(GO:0070208)
0.1	7.5	GO:0097178	ruffle assembly(GO:0097178)
0.1	8.0	GO:0071391	cellular response to estrogen stimulus(GO:0071391)
0.1	6.4	GO:0007274	neuromuscular synaptic transmission(GO:0007274)
0.1	1.3	GO:0060681	branch elongation involved in ureteric bud branching(GO:0060681)
0.1	0.9	GO:0070278	extracellular matrix constituent secretion(GO:0070278)
0.1	0.5	GO:0038018	Wnt receptor catabolic process(GO:0038018)
0.1	2.9	GO:0043981	histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.1	1.3	GO:0042487	regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.1	0.3	GO:0010536	positive regulation of activation of Janus kinase activity(GO:0010536)
0.1	1.3	GO:0030091	protein repair(GO:0030091)
0.1	1.1	GO:0046959	habituation(GO:0046959)
0.1	0.7	GO:1902261	positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.1	1.3	GO:0060088	auditory receptor cell stereocilium organization(GO:0060088)
0.1	10.8	GO:0000380	alternative mRNA splicing, via spliceosome(GO:0000380)
0.1	1.9	GO:0051683	establishment of Golgi localization(GO:0051683)
0.1	0.6	GO:0051182	coenzyme transport(GO:0051182)
0.1	10.2	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.1	6.5	GO:0051865	protein autoubiquitination(GO:0051865)
0.1	12.1	GO:0043149	contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.1	1.9	GO:0030150	protein import into mitochondrial matrix(GO:0030150)
0.1	0.3	GO:0035552	oxidative single-stranded DNA demethylation(GO:0035552)
0.1	1.3	GO:2000543	positive regulation of gastrulation(GO:2000543)
0.1	5.3	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.1	1.2	GO:0019227	neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1	1.0	GO:2000311	regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.1	5.5	GO:0060999	positive regulation of dendritic spine development(GO:0060999)
0.1	1.3	GO:0050901	leukocyte tethering or rolling(GO:0050901)
0.1	2.4	GO:0071577	zinc II ion transmembrane transport(GO:0071577)
0.1	3.2	GO:0045773	positive regulation of axon extension(GO:0045773)
0.1	1.2	GO:0021692	cerebellar Purkinje cell layer morphogenesis(GO:0021692)
0.1	2.1	GO:0008334	histone mRNA metabolic process(GO:0008334)
0.0	2.1	GO:0032008	positive regulation of TOR signaling(GO:0032008)
0.0	2.2	GO:0001954	positive regulation of cell-matrix adhesion(GO:0001954)
0.0	8.1	GO:0071222	cellular response to lipopolysaccharide(GO:0071222)
0.0	2.4	GO:0046839	phospholipid dephosphorylation(GO:0046839)
0.0	2.7	GO:0035722	interleukin-12-mediated signaling pathway(GO:0035722) response to interleukin-12(GO:0070671) cellular response to interleukin-12(GO:0071349)
0.0	2.2	GO:0035329	hippo signaling(GO:0035329)
0.0	0.7	GO:0032625	interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0	0.4	GO:0060371	regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371)
0.0	4.3	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0	4.1	GO:0007218	neuropeptide signaling pathway(GO:0007218)
0.0	4.2	GO:0006970	response to osmotic stress(GO:0006970)
0.0	0.1	GO:0060480	lung goblet cell differentiation(GO:0060480)
0.0	0.7	GO:0007342	fusion of sperm to egg plasma membrane(GO:0007342)
0.0	2.5	GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent(GO:0002479)
0.0	0.5	GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0	3.2	GO:0001578	microtubule bundle formation(GO:0001578)
0.0	0.1	GO:0032929	negative regulation of superoxide anion generation(GO:0032929)
0.0	0.9	GO:0043252	sodium-independent organic anion transport(GO:0043252)
0.0	4.0	GO:0002576	platelet degranulation(GO:0002576)
0.0	0.4	GO:1904776	regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0	1.0	GO:0007214	gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0	1.5	GO:0032418	lysosome localization(GO:0032418)
0.0	0.2	GO:0038171	cannabinoid signaling pathway(GO:0038171)
0.0	0.2	GO:0060605	tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0	1.4	GO:0046854	phosphatidylinositol phosphorylation(GO:0046854)
0.0	0.2	GO:0010603	regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0	0.6	GO:0006654	phosphatidic acid biosynthetic process(GO:0006654)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
15.1	60.2	GO:0033257	Bcl3/NF-kappaB2 complex(GO:0033257)
10.3	31.0	GO:0071065	alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
9.9	89.3	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
9.5	57.2	GO:1990682	CSF1-CSF1R complex(GO:1990682)
5.4	37.9	GO:0042825	TAP complex(GO:0042825)
2.5	22.8	GO:0071144	SMAD2-SMAD3 protein complex(GO:0071144)
2.4	17.1	GO:0005610	laminin-5 complex(GO:0005610)
2.2	39.0	GO:0035631	CD40 receptor complex(GO:0035631)
1.7	18.7	GO:0042612	MHC class I protein complex(GO:0042612)
1.4	20.6	GO:0046581	intercellular canaliculus(GO:0046581)
1.0	11.9	GO:0060091	kinocilium(GO:0060091)
0.9	2.8	GO:0032584	growth cone membrane(GO:0032584)
0.9	54.1	GO:0097542	ciliary tip(GO:0097542)
0.8	24.6	GO:0000145	exocyst(GO:0000145)
0.8	31.3	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.7	46.6	GO:0016235	aggresome(GO:0016235)
0.6	3.2	GO:1990589	ATF4-CREB1 transcription factor complex(GO:1990589)
0.6	11.0	GO:0030127	COPII vesicle coat(GO:0030127)
0.6	6.7	GO:0036449	microtubule minus-end(GO:0036449)
0.5	3.3	GO:0016013	syntrophin complex(GO:0016013)
0.5	6.8	GO:0030126	COPI vesicle coat(GO:0030126)
0.5	32.0	GO:0001772	immunological synapse(GO:0001772)
0.4	12.8	GO:0031143	pseudopodium(GO:0031143)
0.4	9.8	GO:0016580	Sin3 complex(GO:0016580)
0.4	15.8	GO:0005640	nuclear outer membrane(GO:0005640)
0.3	161.6	GO:0045121	membrane raft(GO:0045121)
0.3	109.3	GO:0009897	external side of plasma membrane(GO:0009897)
0.3	10.0	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.3	4.2	GO:0005744	mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.3	1.8	GO:0071598	neuronal ribonucleoprotein granule(GO:0071598)
0.3	2.3	GO:0031415	NatA complex(GO:0031415)
0.3	2.1	GO:0005683	U7 snRNP(GO:0005683)
0.3	48.6	GO:0016363	nuclear matrix(GO:0016363)
0.2	16.1	GO:0055038	recycling endosome membrane(GO:0055038)
0.2	0.9	GO:0031933	telomeric heterochromatin(GO:0031933)
0.2	18.2	GO:1904724	tertiary granule lumen(GO:1904724)
0.2	3.5	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.2	2.3	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
0.2	5.3	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.2	12.7	GO:0031201	SNARE complex(GO:0031201)
0.2	0.5	GO:0016938	kinesin I complex(GO:0016938)
0.2	20.6	GO:0005905	clathrin-coated pit(GO:0005905)
0.2	4.4	GO:0005682	U5 snRNP(GO:0005682)
0.2	3.0	GO:0045180	basal cortex(GO:0045180)
0.2	0.3	GO:0072536	interleukin-23 receptor complex(GO:0072536)
0.1	2.6	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1	6.2	GO:0008180	COP9 signalosome(GO:0008180)
0.1	6.0	GO:0035861	site of double-strand break(GO:0035861)
0.1	12.1	GO:0097517	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1	2.1	GO:0061700	GATOR2 complex(GO:0061700)
0.1	2.6	GO:0042622	photoreceptor outer segment membrane(GO:0042622)
0.1	1.6	GO:0097136	Bcl-2 family protein complex(GO:0097136)
0.1	5.8	GO:0002102	podosome(GO:0002102)
0.1	223.9	GO:0005615	extracellular space(GO:0005615)
0.1	0.9	GO:0030478	actin cap(GO:0030478)
0.1	74.8	GO:0005764	lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.1	3.5	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.1	4.5	GO:0030864	cortical actin cytoskeleton(GO:0030864)
0.1	2.8	GO:0005839	proteasome core complex(GO:0005839)
0.1	4.3	GO:0031594	neuromuscular junction(GO:0031594)
0.1	2.9	GO:0031312	extrinsic component of organelle membrane(GO:0031312)
0.1	1.2	GO:0033391	chromatoid body(GO:0033391)
0.1	1.1	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.1	20.8	GO:0010008	endosome membrane(GO:0010008)
0.1	0.6	GO:0033010	paranodal junction(GO:0033010)
0.1	43.7	GO:0005912	adherens junction(GO:0005912)
0.1	2.9	GO:0044665	MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.1	30.1	GO:0005667	transcription factor complex(GO:0005667)
0.1	1.1	GO:0031011	Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.1	0.4	GO:0071439	clathrin complex(GO:0071439)
0.1	0.7	GO:0030140	trans-Golgi network transport vesicle(GO:0030140)
0.0	5.8	GO:0042383	sarcolemma(GO:0042383)
0.0	6.9	GO:0043209	myelin sheath(GO:0043209)
0.0	0.1	GO:0005828	kinetochore microtubule(GO:0005828)
0.0	3.5	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.0	9.0	GO:0005911	cell-cell junction(GO:0005911)
0.0	3.1	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0	17.8	GO:0012506	vesicle membrane(GO:0012506)
0.0	3.4	GO:0000777	condensed chromosome kinetochore(GO:0000777)
0.0	1.0	GO:0005763	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0	1.8	GO:0072686	mitotic spindle(GO:0072686)
0.0	2.7	GO:0071013	catalytic step 2 spliceosome(GO:0071013)
0.0	1.5	GO:0030496	midbody(GO:0030496)
0.0	1.1	GO:0032420	stereocilium(GO:0032420)
0.0	83.5	GO:0005654	nucleoplasm(GO:0005654)
0.0	2.5	GO:0005875	microtubule associated complex(GO:0005875)
0.0	1.0	GO:0034707	chloride channel complex(GO:0034707)
0.0	1.3	GO:0030426	growth cone(GO:0030426)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
21.9	109.3	GO:0048248	CXCR3 chemokine receptor binding(GO:0048248)
13.5	134.5	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
12.4	37.1	GO:0031731	CCR6 chemokine receptor binding(GO:0031731)
8.2	57.2	GO:0005157	macrophage colony-stimulating factor receptor binding(GO:0005157)
7.6	144.3	GO:0061578	Lys63-specific deubiquitinase activity(GO:0061578)
7.1	56.7	GO:0046979	TAP2 binding(GO:0046979)
5.9	35.2	GO:0004699	calcium-independent protein kinase C activity(GO:0004699)
5.6	22.5	GO:0004906	interferon-gamma receptor activity(GO:0004906)
4.2	12.5	GO:0031896	V2 vasopressin receptor binding(GO:0031896)
3.8	22.8	GO:0031962	mineralocorticoid receptor binding(GO:0031962)
3.1	31.0	GO:0008131	primary amine oxidase activity(GO:0008131)
3.0	17.7	GO:0035800	deubiquitinase activator activity(GO:0035800)
2.7	127.9	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
2.5	22.7	GO:0031730	CCR5 chemokine receptor binding(GO:0031730)
2.2	6.5	GO:0008384	IkappaB kinase activity(GO:0008384)
2.1	49.5	GO:0070628	proteasome binding(GO:0070628)
1.9	20.9	GO:0019958	C-X-C chemokine binding(GO:0019958)
1.5	72.4	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
1.2	4.9	GO:0070139	ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
1.0	35.5	GO:0005035	tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
1.0	66.5	GO:0031593	polyubiquitin binding(GO:0031593)
1.0	5.0	GO:0003870	5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.9	12.8	GO:0017034	Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.9	13.6	GO:0055056	D-glucose transmembrane transporter activity(GO:0055056)
0.9	53.9	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.9	2.6	GO:0052810	1-phosphatidylinositol-5-kinase activity(GO:0052810)
0.8	9.8	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.8	27.6	GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.8	3.1	GO:0097677	STAT family protein binding(GO:0097677)
0.7	2.2	GO:0047223	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity(GO:0047223)
0.7	8.8	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.6	2.6	GO:0047391	alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.6	12.0	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.6	23.4	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.5	5.3	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.5	8.8	GO:0050700	CARD domain binding(GO:0050700)
0.5	1.5	GO:0001601	peptide YY receptor activity(GO:0001601)
0.5	18.8	GO:0051059	NF-kappaB binding(GO:0051059)
0.4	9.4	GO:0070411	activin binding(GO:0048185) I-SMAD binding(GO:0070411)
0.4	26.4	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.4	3.9	GO:0001849	complement component C1q binding(GO:0001849)
0.4	1.3	GO:0098640	integrin binding involved in cell-matrix adhesion(GO:0098640)
0.4	2.1	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
0.4	21.1	GO:0005484	SNAP receptor activity(GO:0005484)
0.4	12.7	GO:0046965	retinoid X receptor binding(GO:0046965)
0.4	8.1	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.4	5.5	GO:0004707	MAP kinase activity(GO:0004707)
0.3	56.1	GO:0004896	cytokine receptor activity(GO:0004896)
0.3	5.2	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.3	2.9	GO:0046972	histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.3	35.0	GO:0001618	virus receptor activity(GO:0001618)
0.3	1.9	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.3	14.0	GO:0001103	RNA polymerase II repressing transcription factor binding(GO:0001103)
0.3	21.3	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.2	8.7	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.2	12.6	GO:0061631	ubiquitin conjugating enzyme activity(GO:0061631)
0.2	9.0	GO:0004708	MAP kinase kinase activity(GO:0004708)
0.2	6.1	GO:0070742	C2H2 zinc finger domain binding(GO:0070742)
0.2	4.8	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.2	31.1	GO:0003727	single-stranded RNA binding(GO:0003727)
0.2	2.4	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.2	29.1	GO:0001047	core promoter binding(GO:0001047)
0.2	64.7	GO:0003713	transcription coactivator activity(GO:0003713)
0.2	1.4	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.2	0.6	GO:0051185	coenzyme transporter activity(GO:0051185)
0.1	2.4	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.1	2.4	GO:0008195	phosphatidate phosphatase activity(GO:0008195)
0.1	1.3	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.1	0.6	GO:0005111	type 2 fibroblast growth factor receptor binding(GO:0005111)
0.1	0.8	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.1	4.1	GO:0005212	structural constituent of eye lens(GO:0005212)
0.1	2.3	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1	37.8	GO:0004713	protein tyrosine kinase activity(GO:0004713)
0.1	0.9	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.1	16.9	GO:0000149	SNARE binding(GO:0000149)
0.1	4.6	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624)
0.1	3.2	GO:0005523	tropomyosin binding(GO:0005523)
0.1	18.8	GO:0004725	protein tyrosine phosphatase activity(GO:0004725)
0.1	7.0	GO:0002039	p53 binding(GO:0002039)
0.1	3.7	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1	0.9	GO:0035497	cAMP response element binding(GO:0035497)
0.1	0.3	GO:0035514	DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.1	2.5	GO:0031698	beta-2 adrenergic receptor binding(GO:0031698)
0.1	0.6	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1	7.2	GO:0051117	ATPase binding(GO:0051117)
0.1	2.2	GO:0001968	fibronectin binding(GO:0001968)
0.1	2.4	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.1	27.1	GO:0003924	GTPase activity(GO:0003924)
0.1	1.5	GO:0031005	filamin binding(GO:0031005)
0.1	0.2	GO:0004949	cannabinoid receptor activity(GO:0004949)
0.1	8.6	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.1	1.1	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.0	0.5	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.0	1.9	GO:0071889	14-3-3 protein binding(GO:0071889)
0.0	18.1	GO:0030246	carbohydrate binding(GO:0030246)
0.0	1.2	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
0.0	0.7	GO:0008179	adenylate cyclase binding(GO:0008179)
0.0	9.2	GO:0061630	ubiquitin protein ligase activity(GO:0061630)
0.0	0.4	GO:0042731	PH domain binding(GO:0042731)
0.0	4.7	GO:0005262	calcium channel activity(GO:0005262)
0.0	0.7	GO:0050681	androgen receptor binding(GO:0050681)
0.0	1.7	GO:0043130	ubiquitin binding(GO:0043130)
0.0	24.6	GO:0005198	structural molecule activity(GO:0005198)
0.0	0.9	GO:0015347	sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0	1.0	GO:0004890	GABA-A receptor activity(GO:0004890)
0.0	0.3	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
0.0	0.2	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.0	0.1	GO:0002162	dystroglycan binding(GO:0002162)
0.0	0.4	GO:0005248	voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0	0.3	GO:0030506	ankyrin binding(GO:0030506)
0.0	0.5	GO:0031491	nucleosome binding(GO:0031491)
0.0	0.1	GO:0019237	centromeric DNA binding(GO:0019237)
0.0	0.1	GO:0004666	prostaglandin-endoperoxide synthase activity(GO:0004666) arachidonate 15-lipoxygenase activity(GO:0050473)
0.0	0.5	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
5.6	349.3	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
2.2	88.0	PID IL27 PATHWAY	IL27-mediated signaling events
2.1	23.6	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
2.0	74.2	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
1.8	57.2	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
1.7	31.0	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
1.6	135.3	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
1.2	26.7	PID IL23 PATHWAY	IL23-mediated signaling events
1.1	47.3	PID CD40 PATHWAY	CD40/CD40L signaling
1.0	49.6	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.9	79.2	PID IL4 2PATHWAY	IL4-mediated signaling events
0.9	17.1	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.8	17.0	PID IL12 2PATHWAY	IL12-mediated signaling events
0.8	32.0	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.8	22.8	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.6	22.0	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.4	178.7	NABA SECRETED FACTORS	Genes encoding secreted soluble factors
0.3	1.0	PID TRAIL PATHWAY	TRAIL signaling pathway
0.3	16.5	PID CD8 TCR DOWNSTREAM PATHWAY	Downstream signaling in naïve CD8+ T cells
0.3	8.1	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.2	3.1	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.2	21.2	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
0.2	43.9	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
0.2	9.1	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.2	3.9	ST ADRENERGIC	Adrenergic Pathway
0.2	4.2	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.1	3.1	PID TCPTP PATHWAY	Signaling events mediated by TCPTP
0.1	2.6	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.1	6.7	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.1	5.0	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.1	1.7	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.1	2.9	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.1	1.3	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1	3.7	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.1	1.2	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.1	4.5	PID ILK PATHWAY	Integrin-linked kinase signaling
0.0	2.9	PID E2F PATHWAY	E2F transcription factor network
0.0	0.7	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.0	1.4	ST INTEGRIN SIGNALING PATHWAY	Integrin Signaling Pathway
0.0	1.1	PID P75 NTR PATHWAY	p75(NTR)-mediated signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
5.7	285.6	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
4.2	288.6	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
4.1	90.4	REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX	Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
3.5	74.1	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
3.2	28.4	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
2.0	56.7	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
1.8	9.0	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
1.7	26.9	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
1.4	26.9	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
1.2	23.9	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
1.0	100.7	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.8	21.1	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.7	12.0	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.7	32.2	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.7	31.3	REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.7	23.4	REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	Genes involved in CD28 dependent PI3K/Akt signaling
0.6	13.6	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.6	27.6	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.6	14.5	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.4	12.5	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.4	13.3	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.3	12.4	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.3	10.7	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.3	8.8	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.2	2.8	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.2	3.5	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.2	1.6	REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON	Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.2	24.0	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.2	5.0	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.2	18.4	REACTOME DOWNSTREAM SIGNAL TRANSDUCTION	Genes involved in Downstream signal transduction
0.2	14.6	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1	1.2	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.1	19.6	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.1	2.1	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.1	1.5	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.1	1.9	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.1	2.4	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.1	2.5	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.1	6.1	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.1	1.6	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
0.1	2.2	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.1	3.2	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.1	4.2	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.1	1.1	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	2.7	REACTOME PI METABOLISM	Genes involved in PI Metabolism
0.0	2.5	REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C	Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.0	7.8	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0	0.5	REACTOME ELONGATION ARREST AND RECOVERY	Genes involved in Elongation arrest and recovery
0.0	1.1	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	1.0	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.0	1.0	REACTOME TRAFFICKING OF AMPA RECEPTORS	Genes involved in Trafficking of AMPA receptors
0.0	2.7	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.0	0.6	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.0	0.6	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules