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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for RELB

Z-value: 1.14

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Transcription factors associated with RELB

Gene Symbol Gene ID Gene Info
ENSG00000104856.14 RELB

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RELBhg38_v1_chr19_+_45001430_450015250.892.9e-09Click!

Activity profile of RELB motif

Sorted Z-values of RELB motif

Network of associatons between targets according to the STRING database.

First level regulatory network of RELB

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr6_-_29559724 10.99 ENST00000377050.5
ubiquitin D
chr9_-_120926752 7.64 ENST00000373887.8
TNF receptor associated factor 1
chr1_-_173050931 7.06 ENST00000404377.5
TNF superfamily member 18
chr4_+_73836667 6.72 ENST00000226317.10
C-X-C motif chemokine ligand 6
chr1_-_7940825 6.51 ENST00000377507.8
TNF receptor superfamily member 9
chr11_+_102317492 5.08 ENST00000673846.1
baculoviral IAP repeat containing 3
chr1_+_109910485 4.97 ENST00000525659.5
colony stimulating factor 1
chr14_+_103123452 4.91 ENST00000558056.1
ENST00000560869.6
TNF alpha induced protein 2
chr6_+_14117764 4.82 ENST00000379153.4
CD83 molecule
chr12_+_77830886 4.66 ENST00000397909.7
ENST00000549464.5
neuron navigator 3
chr19_+_45001430 4.62 ENST00000625761.2
ENST00000505236.1
ENST00000221452.13
RELB proto-oncogene, NF-kB subunit
chr4_-_73998669 4.54 ENST00000296027.5
C-X-C motif chemokine ligand 5
chr4_+_102501885 4.28 ENST00000505458.5
nuclear factor kappa B subunit 1
chr5_-_151080978 4.00 ENST00000520931.5
ENST00000521591.6
ENST00000520695.5
ENST00000610535.5
ENST00000518977.5
ENST00000389378.6
ENST00000610874.4
TNFAIP3 interacting protein 1
chr5_+_10564064 3.91 ENST00000296657.7
ankyrin repeat domain 33B
chr1_+_109910840 3.88 ENST00000329608.11
ENST00000488198.5
colony stimulating factor 1
chr6_+_32854179 3.75 ENST00000374859.3
proteasome 20S subunit beta 9
chr11_+_102317542 3.70 ENST00000532808.5
baculoviral IAP repeat containing 3
chr11_+_102317450 3.64 ENST00000615299.4
ENST00000527309.2
ENST00000526421.6
ENST00000263464.9
baculoviral IAP repeat containing 3
chr10_+_102394488 3.54 ENST00000369966.8
nuclear factor kappa B subunit 2
chr12_-_48865863 3.53 ENST00000309739.6
Rho family GTPase 1
chr6_-_142946312 3.36 ENST00000367604.6
HIVEP zinc finger 2
chr2_-_162318475 3.26 ENST00000648433.1
interferon induced with helicase C domain 1
chr6_+_137867241 3.23 ENST00000612899.5
ENST00000420009.5
TNF alpha induced protein 3
chr6_+_137867414 3.22 ENST00000237289.8
ENST00000433680.1
TNF alpha induced protein 3
chr9_-_133479075 3.18 ENST00000414172.1
ENST00000371897.8
ENST00000371899.9
solute carrier family 2 member 6
chr12_-_57110284 2.97 ENST00000543873.6
ENST00000554663.5
ENST00000557635.5
signal transducer and activator of transcription 6
chr5_-_147453888 2.82 ENST00000398514.7
dihydropyrimidinase like 3
chr17_+_42288464 2.45 ENST00000590726.7
ENST00000678903.1
ENST00000590949.6
ENST00000676585.1
ENST00000588868.5
signal transducer and activator of transcription 5A
chr22_-_19525369 2.28 ENST00000403084.1
ENST00000413119.2
claudin 5
chr17_+_42288429 2.21 ENST00000676631.1
ENST00000677893.1
signal transducer and activator of transcription 5A
chr18_+_58149314 2.20 ENST00000435432.6
ENST00000357895.9
ENST00000586263.5
NEDD4 like E3 ubiquitin protein ligase
chr16_+_50696999 2.11 ENST00000300589.6
nucleotide binding oligomerization domain containing 2
chr4_-_184474518 2.10 ENST00000393593.8
interferon regulatory factor 2
chr8_+_53880867 2.09 ENST00000522225.5
regulator of G protein signaling 20
chr6_+_29723340 2.08 ENST00000334668.8
major histocompatibility complex, class I, F
chr8_+_53880894 2.02 ENST00000276500.4
regulator of G protein signaling 20
chr6_+_29723421 1.91 ENST00000259951.12
ENST00000434407.6
major histocompatibility complex, class I, F
chr21_+_33403466 1.85 ENST00000405436.5
interferon gamma receptor 2
chr19_-_4338786 1.80 ENST00000601482.1
ENST00000600324.5
ENST00000594605.6
signal transducing adaptor family member 2
chr2_-_203535253 1.80 ENST00000457812.5
ENST00000319170.10
ENST00000630330.2
ENST00000308091.8
ENST00000453034.5
ENST00000420371.2
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
chr2_+_68467544 1.78 ENST00000303795.9
aprataxin and PNKP like factor
chr2_-_162318613 1.77 ENST00000649979.2
ENST00000421365.2
interferon induced with helicase C domain 1
chr10_+_13100075 1.76 ENST00000378747.8
ENST00000378757.6
ENST00000378752.7
ENST00000378748.7
optineurin
chr10_+_13099585 1.72 ENST00000378764.6
optineurin
chr2_+_32628026 1.71 ENST00000448773.5
ENST00000317907.9
tetratricopeptide repeat domain 27
chr10_+_12349533 1.70 ENST00000619168.5
calcium/calmodulin dependent protein kinase ID
chr2_+_26346086 1.68 ENST00000613142.4
ENST00000260585.12
ENST00000447170.1
selenoprotein I
chr4_+_73869385 1.57 ENST00000395761.4
C-X-C motif chemokine ligand 1
chr9_-_32526185 1.47 ENST00000379883.3
ENST00000379868.6
ENST00000679859.1
DExD/H-box helicase 58
chr6_+_29942523 1.45 ENST00000376809.10
ENST00000376802.2
ENST00000638375.1
major histocompatibility complex, class I, A
chr1_+_159204860 1.41 ENST00000368122.4
ENST00000368121.6
atypical chemokine receptor 1 (Duffy blood group)
chr10_+_94545852 1.39 ENST00000394036.5
ENST00000394045.5
helicase, lymphoid specific
chr5_-_59893718 1.39 ENST00000340635.11
phosphodiesterase 4D
chr2_-_96505345 1.38 ENST00000310865.7
ENST00000451794.6
neuralized E3 ubiquitin protein ligase 3
chr1_-_64966488 1.36 ENST00000342505.5
ENST00000673254.1
Janus kinase 1
chr21_+_33403391 1.35 ENST00000290219.11
ENST00000381995.5
interferon gamma receptor 2
chr3_-_39153512 1.28 ENST00000273153.10
cysteine and serine rich nuclear protein 1
chr8_+_144095054 1.23 ENST00000318911.5
cytochrome c1
chr10_-_73414027 1.21 ENST00000372921.10
ENST00000372919.8
annexin A7
chr3_+_183253230 1.21 ENST00000326505.4
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
chr10_+_94545777 1.19 ENST00000348459.10
ENST00000419900.5
ENST00000630929.2
helicase, lymphoid specific
chr6_-_11779606 1.11 ENST00000506810.1
androgen dependent TFPI regulating protein
chr2_-_100104530 1.10 ENST00000432037.5
ENST00000673232.1
ENST00000423966.6
ENST00000409236.6
AF4/FMR2 family member 3
chr12_-_54588516 1.09 ENST00000547431.5
protein phosphatase 1 regulatory inhibitor subunit 1A
chr19_-_17847962 1.06 ENST00000458235.7
ENST00000534444.1
Janus kinase 3
chr7_+_116524984 1.05 ENST00000614113.5
ENST00000393470.1
caveolin 1
chr17_-_79009778 1.03 ENST00000591773.5
ENST00000588611.5
ENST00000586916.6
ENST00000592033.5
ENST00000588075.5
ENST00000302345.6
ENST00000591811.1
calcium activated nucleotidase 1
chr12_-_12562851 1.03 ENST00000298573.9
dual specificity phosphatase 16
chrX_-_11665908 1.01 ENST00000337414.9
Rho GTPase activating protein 6
chr7_+_116525524 0.99 ENST00000405348.6
caveolin 1
chr2_-_199955464 0.95 ENST00000354611.9
tRNA-yW synthesizing protein 5
chr11_-_5154757 0.94 ENST00000380367.3
olfactory receptor family 52 subfamily A member 1
chr1_-_247078804 0.93 ENST00000366503.3
zinc finger protein 670
chr6_-_136525961 0.91 ENST00000438100.6
microtubule associated protein 7
chr1_-_160343235 0.91 ENST00000368069.7
ENST00000241704.8
ENST00000647683.1
ENST00000649787.1
COPI coat complex subunit alpha
chr2_+_207529731 0.89 ENST00000430624.5
cAMP responsive element binding protein 1
chrX_+_73447042 0.89 ENST00000373514.3
caudal type homeobox 4
chr6_-_36387566 0.89 ENST00000339796.9
ENST00000627426.2
ETS variant transcription factor 7
chr10_+_87659839 0.88 ENST00000456849.2
3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr5_+_68288346 0.87 ENST00000320694.12
phosphoinositide-3-kinase regulatory subunit 1
chr17_-_7687427 0.87 ENST00000514944.5
ENST00000503591.1
ENST00000610292.4
ENST00000420246.6
ENST00000455263.6
ENST00000610538.4
ENST00000622645.4
ENST00000445888.6
ENST00000619485.4
ENST00000509690.5
ENST00000604348.5
ENST00000269305.9
ENST00000620739.4
tumor protein p53
chr8_-_12755457 0.86 ENST00000398246.8
LON peptidase N-terminal domain and ring finger 1
chr17_-_79009731 0.86 ENST00000392446.10
ENST00000590370.5
ENST00000591625.5
calcium activated nucleotidase 1
chr10_-_72215903 0.86 ENST00000526751.5
ENST00000672774.1
ENST00000394919.5
ENST00000394915.7
activating signal cointegrator 1 complex subunit 1
chr15_-_101277287 0.84 ENST00000528346.1
ENST00000531964.5
ENST00000398226.7
ENST00000526049.6
selenoprotein S
chr14_-_72894091 0.83 ENST00000556509.6
double PHD fingers 3
chr1_+_100538131 0.82 ENST00000315033.5
G protein-coupled receptor 88
chr10_-_72216267 0.78 ENST00000342444.8
ENST00000533958.1
ENST00000672957.1
ENST00000527593.5
ENST00000672940.1
ENST00000530461.5
ENST00000317168.11
ENST00000524829.5
activating signal cointegrator 1 complex subunit 1
chr12_+_2053545 0.78 ENST00000682336.1
ENST00000344100.7
ENST00000399591.5
ENST00000399595.5
ENST00000399597.5
ENST00000399601.5
ENST00000399606.5
ENST00000399621.5
ENST00000399629.5
ENST00000399637.5
ENST00000399638.5
ENST00000399644.5
ENST00000399649.5
ENST00000402845.7
ENST00000682686.1
calcium voltage-gated channel subunit alpha1 C
chr1_-_153540694 0.76 ENST00000368717.2
S100 calcium binding protein A5
chr19_+_38899946 0.76 ENST00000572515.5
ENST00000313582.6
ENST00000575359.5
NFKB inhibitor beta
chr20_-_18497218 0.75 ENST00000337227.9
RB binding protein 9, serine hydrolase
chr19_+_38899680 0.75 ENST00000576510.5
ENST00000392079.7
NFKB inhibitor beta
chr1_-_204411804 0.75 ENST00000367188.5
protein phosphatase 1 regulatory subunit 15B
chr16_-_2009797 0.75 ENST00000563630.6
ENST00000562103.2
zinc finger protein 598, E3 ubiquitin ligase
chr1_-_196608359 0.74 ENST00000609185.5
ENST00000451324.6
ENST00000367433.9
ENST00000294725.14
potassium sodium-activated channel subfamily T member 2
chr2_-_27495185 0.74 ENST00000264703.4
fibronectin type III domain containing 4
chr4_+_39044995 0.74 ENST00000261425.7
ENST00000508137.6
kelch like family member 5
chr16_+_57358775 0.73 ENST00000219235.5
C-C motif chemokine ligand 22
chr10_+_94762673 0.72 ENST00000480405.2
ENST00000371321.9
cytochrome P450 family 2 subfamily C member 19
chr15_-_78944985 0.70 ENST00000615999.5
ENST00000677789.1
ENST00000676880.1
ENST00000677936.1
ENST00000220166.10
ENST00000677810.1
ENST00000678644.1
ENST00000677534.1
ENST00000677316.1
cathepsin H
chr1_+_25338294 0.70 ENST00000374358.5
transmembrane protein 50A
chr22_-_37244417 0.69 ENST00000405484.5
ENST00000441619.5
ENST00000406508.5
Rac family small GTPase 2
chr14_+_102777461 0.68 ENST00000560371.5
ENST00000347662.8
TNF receptor associated factor 3
chr6_-_36387736 0.68 ENST00000373737.8
ENST00000373738.4
ENST00000538992.3
ENST00000615781.4
ENST00000620358.4
ETS variant transcription factor 7
chr4_+_4859658 0.68 ENST00000382723.5
msh homeobox 1
chr3_-_108222383 0.68 ENST00000264538.4
intraflagellar transport 57
chr7_-_22500152 0.67 ENST00000406890.6
ENST00000678116.1
ENST00000424363.5
STEAP family member 1B
chr14_+_102777555 0.65 ENST00000539721.5
ENST00000560463.5
TNF receptor associated factor 3
chr11_+_72114840 0.65 ENST00000622388.4
folate receptor gamma
chr6_-_136526472 0.64 ENST00000454590.5
ENST00000432797.6
microtubule associated protein 7
chr6_-_36387654 0.64 ENST00000340181.9
ETS variant transcription factor 7
chrX_+_15500800 0.63 ENST00000348343.11
BMX non-receptor tyrosine kinase
chr9_-_133348022 0.63 ENST00000446777.5
ENST00000610888.4
ENST00000371999.5
ENST00000494177.6
ENST00000343730.10
ENST00000457204.2
mediator complex subunit 22
chr7_+_116525028 0.62 ENST00000341049.7
caveolin 1
chr12_-_124989053 0.61 ENST00000308736.7
DEAH-box helicase 37
chr4_+_77605807 0.60 ENST00000682537.1
C-X-C motif chemokine ligand 13
chr2_+_64454506 0.60 ENST00000409537.2
galectin like
chr16_-_57284654 0.60 ENST00000613167.4
ENST00000219207.10
ENST00000569059.5
plasmolipin
chr4_-_74099187 0.60 ENST00000508487.3
C-X-C motif chemokine ligand 2
chr2_+_64453969 0.59 ENST00000464281.5
galectin like
chr11_+_64284794 0.59 ENST00000539851.5
G protein-coupled receptor 137
chr6_-_35688907 0.59 ENST00000539068.5
ENST00000357266.9
FKBP prolyl isomerase 5
chr1_+_109910892 0.59 ENST00000369802.7
ENST00000420111.6
colony stimulating factor 1
chr19_-_40218339 0.59 ENST00000311308.6
tetratricopeptide repeat domain 9B
chr8_-_100950549 0.58 ENST00000395951.7
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta
chr14_-_100568475 0.58 ENST00000553553.6
brain enriched guanylate kinase associated
chr15_-_30991415 0.58 ENST00000563714.5
myotubularin related protein 10
chr10_+_84328625 0.56 ENST00000224756.12
coiled-coil serine rich protein 2
chr14_+_102777433 0.56 ENST00000392745.8
TNF receptor associated factor 3
chr12_+_6199715 0.56 ENST00000382518.6
ENST00000642746.1
ENST00000538834.6
CD9 molecule
chr8_+_49911604 0.55 ENST00000642164.1
ENST00000644093.1
ENST00000643999.1
ENST00000647073.1
ENST00000646880.1
syntrophin gamma 1
chr15_-_43302255 0.55 ENST00000452443.3
transglutaminase 7
chr11_+_64285219 0.55 ENST00000377702.8
G protein-coupled receptor 137
chr2_+_124025280 0.55 ENST00000431078.1
ENST00000682447.1
contactin associated protein family member 5
chr20_-_44651683 0.54 ENST00000537820.1
ENST00000372874.9
adenosine deaminase
chr10_-_102837406 0.54 ENST00000369887.4
ENST00000638272.1
ENST00000639393.1
ENST00000638971.1
ENST00000638190.1
cytochrome P450 family 17 subfamily A member 1
chrX_-_66033664 0.54 ENST00000427538.5
V-set and immunoglobulin domain containing 4
chr6_+_132570322 0.54 ENST00000275198.1
trace amine associated receptor 6
chr6_+_101393699 0.54 ENST00000369134.9
ENST00000684068.1
ENST00000683903.1
ENST00000681975.1
glutamate ionotropic receptor kainate type subunit 2
chr3_-_155854375 0.54 ENST00000643144.2
ENST00000359479.7
ENST00000646424.1
solute carrier family 33 member 1
chr7_+_104328603 0.52 ENST00000401970.3
ENST00000424859.7
LHFPL tetraspan subfamily member 3
chr16_-_66925526 0.52 ENST00000299759.11
ENST00000420652.5
RRAD, Ras related glycolysis inhibitor and calcium channel regulator
chr1_+_180196536 0.52 ENST00000443059.1
quiescin sulfhydryl oxidase 1
chr2_+_218880844 0.51 ENST00000258411.8
Wnt family member 10A
chr3_+_161221280 0.50 ENST00000472947.5
ENST00000351193.7
ENST00000463518.5
NMD3 ribosome export adaptor
chr7_-_138001794 0.50 ENST00000616381.4
ENST00000620715.4
cAMP responsive element binding protein 3 like 2
chr11_+_75717811 0.49 ENST00000198801.10
monoacylglycerol O-acyltransferase 2
chr3_+_184314525 0.49 ENST00000392537.6
ENST00000444134.5
ENST00000450424.5
ENST00000421110.5
ENST00000435046.7
ENST00000382330.7
ENST00000426123.5
ENST00000346169.7
ENST00000350481.9
ENST00000455679.5
ENST00000440448.5
eukaryotic translation initiation factor 4 gamma 1
chr8_+_49911396 0.48 ENST00000642720.2
syntrophin gamma 1
chr11_+_64284982 0.48 ENST00000539833.5
G protein-coupled receptor 137
chr2_+_207711631 0.47 ENST00000295414.8
ENST00000420822.1
ENST00000339882.9
cyclin Y like 1
chr6_-_136526177 0.47 ENST00000617204.4
microtubule associated protein 7
chr4_+_61200318 0.47 ENST00000683033.1
adhesion G protein-coupled receptor L3
chr17_-_42676980 0.46 ENST00000587627.1
ENST00000591022.6
ENST00000293349.10
pleckstrin homology, MyTH4 and FERM domain containing H3
chr1_+_23791203 0.46 ENST00000374503.7
ENST00000374502.7
lysophospholipase 2
chr2_-_89100352 0.46 ENST00000479981.1
immunoglobulin kappa variable 1-16
chr1_-_74673786 0.45 ENST00000326665.10
glutamate rich 3
chr12_-_8662619 0.45 ENST00000544889.1
ENST00000543369.5
microfibril associated protein 5
chr11_+_64284822 0.45 ENST00000536667.5
G protein-coupled receptor 137
chr3_+_113947901 0.45 ENST00000330212.7
ENST00000498275.5
zinc finger DHHC-type palmitoyltransferase 23
chr12_-_14567714 0.45 ENST00000240617.10
phospholipase B domain containing 1
chr11_+_61792878 0.44 ENST00000305885.3
ENST00000535723.1
flap structure-specific endonuclease 1
chr3_+_133805789 0.44 ENST00000678299.1
SRP receptor subunit beta
chr8_+_100158576 0.44 ENST00000388798.7
sperm associated antigen 1
chr2_+_153871909 0.43 ENST00000392825.8
ENST00000434213.1
polypeptide N-acetylgalactosaminyltransferase 13
chr20_-_2470749 0.43 ENST00000381342.7
ENST00000438552.6
small nuclear ribonucleoprotein polypeptides B and B1
chr21_+_44455471 0.43 ENST00000291592.6
leucine rich repeat containing 3
chr1_-_53738024 0.42 ENST00000628545.1
GLIS family zinc finger 1
chr19_-_4540028 0.42 ENST00000306390.7
leucine rich alpha-2-glycoprotein 1
chr2_+_158968608 0.41 ENST00000263635.8
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
chr20_-_34303345 0.41 ENST00000217426.7
adenosylhomocysteinase
chr21_-_41953997 0.41 ENST00000380486.4
C2 calcium dependent domain containing 2
chr6_+_36196710 0.41 ENST00000357641.10
bromodomain and PHD finger containing 3
chr1_-_202159977 0.41 ENST00000367279.8
protein tyrosine phosphatase non-receptor type 7
chr1_-_99005003 0.41 ENST00000672681.1
ENST00000370188.7
phospholipid phosphatase related 5
chr19_-_41363930 0.41 ENST00000675972.1
B9 domain containing 2
chr8_+_54616078 0.40 ENST00000220676.2
RP1 axonemal microtubule associated
chr1_-_202161575 0.40 ENST00000309017.7
ENST00000477554.5
ENST00000492451.1
protein tyrosine phosphatase non-receptor type 7
chr17_-_7238171 0.40 ENST00000574236.5
ENST00000572789.5
PHD finger protein 23
chr20_+_59300703 0.40 ENST00000395654.3
endothelin 3
chr1_+_37474572 0.40 ENST00000373087.7
zinc finger CCCH-type containing 12A
chr16_+_280448 0.40 ENST00000447871.5
Rho GDP dissociation inhibitor gamma
chr2_+_231781669 0.40 ENST00000410024.5
ENST00000611614.4
ENST00000409295.5
ENST00000409091.5
COP9 signalosome subunit 7B
chr6_+_138161932 0.39 ENST00000251691.5
ARFGEF family member 3
chr8_-_33567118 0.39 ENST00000256257.2
ring finger protein 122
chr8_+_22165358 0.39 ENST00000306349.13
ENST00000306385.10
bone morphogenetic protein 1
chr9_-_127930777 0.39 ENST00000388747.9
phosphatidylinositol-4-phosphate 5-kinase like 1
chr18_+_36297661 0.39 ENST00000257209.8
ENST00000590592.5
ENST00000359247.8
formin homology 2 domain containing 3
chr7_+_86643902 0.38 ENST00000361669.7
glutamate metabotropic receptor 3
chr10_+_68901258 0.38 ENST00000373585.8
DExD-box helicase 50
chr17_+_7380534 0.38 ENST00000570896.5
tyrosine kinase non receptor 1
chrX_+_103776493 0.38 ENST00000433491.5
ENST00000612423.4
ENST00000443502.5
proteolipid protein 1
chr3_+_184314495 0.37 ENST00000352767.7
ENST00000414031.5
eukaryotic translation initiation factor 4 gamma 1
chr17_-_42388360 0.37 ENST00000678960.1
ENST00000404395.3
ENST00000389272.7
ENST00000677421.1
ENST00000585517.5
ENST00000264657.10
ENST00000678048.1
ENST00000678674.1
ENST00000678913.1
ENST00000678572.1
ENST00000678906.1
signal transducer and activator of transcription 3
chr17_+_67377413 0.37 ENST00000580974.5
phosphatidylinositol transfer protein cytoplasmic 1
chr11_+_75240761 0.37 ENST00000562197.3
trophoblast glycoprotein like
chr20_-_4815100 0.36 ENST00000379376.2
Ras association domain family member 2
chr1_-_6261053 0.36 ENST00000377893.3
G protein-coupled receptor 153

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 9.4 GO:0042488 positive regulation of odontogenesis of dentin-containing tooth(GO:0042488) mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) positive regulation of microglial cell migration(GO:1904141)
2.2 6.5 GO:0034147 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429)
1.8 7.1 GO:2000329 negative regulation of T-helper 17 cell lineage commitment(GO:2000329)
1.4 11.0 GO:0070842 aggresome assembly(GO:0070842)
1.3 4.0 GO:0052250 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
1.3 6.5 GO:0034344 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
1.1 6.5 GO:2001180 negative regulation of interleukin-10 secretion(GO:2001180)
1.1 2.1 GO:1902523 positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.9 12.4 GO:0070424 regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
0.9 3.5 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.9 2.6 GO:0031508 pericentric heterochromatin assembly(GO:0031508)
0.9 4.3 GO:1900127 positive regulation of hyaluronan biosynthetic process(GO:1900127)
0.7 3.0 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.7 4.7 GO:0000255 allantoin metabolic process(GO:0000255)
0.7 2.7 GO:1900085 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.5 5.4 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.5 4.8 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.5 1.1 GO:0002730 regulation of dendritic cell cytokine production(GO:0002730)
0.5 3.4 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.4 0.9 GO:0097252 oligodendrocyte apoptotic process(GO:0097252)
0.4 14.8 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.3 0.3 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.3 4.9 GO:0051601 exocyst localization(GO:0051601)
0.3 1.8 GO:0051106 positive regulation of DNA ligation(GO:0051106)
0.3 0.9 GO:0000103 sulfate assimilation(GO:0000103)
0.3 0.8 GO:0061743 motor learning(GO:0061743)
0.3 1.3 GO:0045204 MAPK export from nucleus(GO:0045204)
0.3 2.3 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.2 0.7 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.2 1.2 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.2 0.7 GO:1902724 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730) positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
0.2 3.5 GO:0016322 neuron remodeling(GO:0016322)
0.2 4.6 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.2 1.9 GO:0008063 Toll signaling pathway(GO:0008063)
0.2 2.2 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.2 0.5 GO:0002314 germinal center B cell differentiation(GO:0002314) mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906) negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) xanthine metabolic process(GO:0046110) negative regulation of mucus secretion(GO:0070256)
0.2 0.7 GO:0060448 dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.2 0.7 GO:0035880 embryonic nail plate morphogenesis(GO:0035880) activation of meiosis(GO:0090427)
0.2 0.8 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.2 0.6 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634) negative regulation of endothelial cell chemotaxis(GO:2001027)
0.2 1.4 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.1 0.4 GO:0030451 regulation of complement activation, alternative pathway(GO:0030451) negative regulation of complement activation, alternative pathway(GO:0045957)
0.1 1.4 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1 0.5 GO:1904550 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.1 0.5 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 1.5 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.1 0.3 GO:1901053 sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053)
0.1 0.9 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.1 0.6 GO:0051182 coenzyme transport(GO:0051182)
0.1 0.4 GO:0002439 chronic inflammatory response to antigenic stimulus(GO:0002439)
0.1 0.7 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.1 0.5 GO:1904751 positive regulation of protein localization to nucleolus(GO:1904751)
0.1 0.3 GO:1904899 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.1 0.4 GO:1990868 negative regulation by host of viral genome replication(GO:0044828) response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869)
0.1 3.2 GO:0060334 regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.1 0.4 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.1 0.3 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.1 0.7 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.1 7.9 GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.1 3.2 GO:0035428 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.1 0.7 GO:1903898 negative regulation of PERK-mediated unfolded protein response(GO:1903898) negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912)
0.1 0.9 GO:0035585 calcium-mediated signaling using extracellular calcium source(GO:0035585)
0.1 2.3 GO:0051764 actin crosslink formation(GO:0051764)
0.1 0.3 GO:0097325 melanocyte proliferation(GO:0097325)
0.1 0.4 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.1 0.2 GO:0016999 antibiotic metabolic process(GO:0016999) cellular amide catabolic process(GO:0043605)
0.1 0.9 GO:0030157 pancreatic juice secretion(GO:0030157)
0.1 0.5 GO:0061709 reticulophagy(GO:0061709)
0.1 0.4 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.1 0.5 GO:0002084 protein depalmitoylation(GO:0002084)
0.1 0.6 GO:0001865 NK T cell differentiation(GO:0001865)
0.1 0.3 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.1 0.5 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.0 GO:1903719 regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
0.0 0.2 GO:2000360 positive regulation of female gonad development(GO:2000196) negative regulation of binding of sperm to zona pellucida(GO:2000360)
0.0 0.1 GO:0089709 histidine transport(GO:0015817) cellular response to potassium ion starvation(GO:0051365) L-histidine transmembrane transport(GO:0089709) L-histidine transport(GO:1902024)
0.0 0.2 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.0 0.9 GO:0051531 NFAT protein import into nucleus(GO:0051531)
0.0 4.3 GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent(GO:0002479)
0.0 0.6 GO:0009414 response to water deprivation(GO:0009414)
0.0 0.3 GO:2001184 positive regulation of interleukin-12 secretion(GO:2001184)
0.0 0.6 GO:0015884 folic acid transport(GO:0015884)
0.0 0.5 GO:0048733 sebaceous gland development(GO:0048733)
0.0 0.5 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.3 GO:2000490 negative regulation of hepatic stellate cell activation(GO:2000490)
0.0 0.2 GO:1903232 melanosome assembly(GO:1903232)
0.0 1.2 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.4 GO:0072656 maintenance of protein location in mitochondrion(GO:0072656)
0.0 0.4 GO:0046549 photoreceptor cell outer segment organization(GO:0035845) retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 1.0 GO:0051895 negative regulation of focal adhesion assembly(GO:0051895)
0.0 0.2 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
0.0 1.3 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.5 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.0 0.5 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.2 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.0 0.5 GO:0042448 progesterone metabolic process(GO:0042448)
0.0 0.3 GO:0097084 vascular smooth muscle cell development(GO:0097084)
0.0 0.4 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.4 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.0 0.3 GO:0044130 negative regulation of growth of symbiont in host(GO:0044130)
0.0 0.4 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.7 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.1 GO:0051935 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.0 0.4 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.0 0.4 GO:0001502 cartilage condensation(GO:0001502)
0.0 0.2 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.0 2.1 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 1.2 GO:0035116 embryonic hindlimb morphogenesis(GO:0035116)
0.0 0.4 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.0 0.7 GO:0060972 left/right pattern formation(GO:0060972)
0.0 0.1 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
0.0 0.8 GO:0018345 protein palmitoylation(GO:0018345)
0.0 1.6 GO:0016266 O-glycan processing(GO:0016266)
0.0 2.1 GO:0030166 proteoglycan biosynthetic process(GO:0030166)
0.0 0.3 GO:1903012 positive regulation of bone development(GO:1903012)
0.0 0.5 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.0 0.4 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.3 GO:0010529 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
0.0 0.1 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.0 0.2 GO:1902856 negative regulation of nonmotile primary cilium assembly(GO:1902856)
0.0 1.8 GO:0006970 response to osmotic stress(GO:0006970)
0.0 0.3 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.9 GO:0009948 anterior/posterior axis specification(GO:0009948)
0.0 0.7 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.0 0.4 GO:0097062 dendritic spine maintenance(GO:0097062)
0.0 0.6 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.3 GO:0015671 oxygen transport(GO:0015671)
0.0 0.2 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.4 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.0 0.7 GO:0051204 protein insertion into mitochondrial membrane(GO:0051204)
0.0 0.2 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.6 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.1 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 0.4 GO:0050873 brown fat cell differentiation(GO:0050873)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 9.4 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.9 3.5 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.7 6.3 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.5 5.4 GO:0042612 MHC class I protein complex(GO:0042612)
0.5 3.7 GO:1990111 spermatoproteasome complex(GO:1990111)
0.2 0.9 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.2 2.7 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.2 4.9 GO:0000145 exocyst(GO:0000145)
0.2 0.8 GO:0036502 Derlin-1-VIMP complex(GO:0036502)
0.2 10.9 GO:0016235 aggresome(GO:0016235)
0.1 1.2 GO:0042584 chromaffin granule membrane(GO:0042584)
0.1 0.5 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.1 1.9 GO:0035631 CD40 receptor complex(GO:0035631)
0.1 2.6 GO:0005721 pericentric heterochromatin(GO:0005721)
0.1 1.2 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.1 3.4 GO:0005640 nuclear outer membrane(GO:0005640)
0.1 0.3 GO:0008537 proteasome activator complex(GO:0008537)
0.1 0.2 GO:0031085 BLOC-3 complex(GO:0031085)
0.1 1.0 GO:0016013 syntrophin complex(GO:0016013)
0.1 0.2 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.1 2.3 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.7 GO:0097208 alveolar lamellar body(GO:0097208)
0.1 0.9 GO:0030126 COPI vesicle coat(GO:0030126)
0.1 0.4 GO:0005683 U7 snRNP(GO:0005683)
0.0 0.4 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 1.1 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.7 GO:0044292 dendrite terminus(GO:0044292)
0.0 0.9 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.4 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 1.8 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.3 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 2.9 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.3 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.1 GO:0016938 kinesin I complex(GO:0016938)
0.0 0.2 GO:0002081 outer acrosomal membrane(GO:0002081)
0.0 2.1 GO:0031941 filamentous actin(GO:0031941)
0.0 2.6 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.2 GO:0032010 phagolysosome(GO:0032010)
0.0 0.4 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 1.5 GO:0005771 multivesicular body(GO:0005771)
0.0 1.5 GO:0008180 COP9 signalosome(GO:0008180)
0.0 1.1 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 8.2 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 1.4 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 10.6 GO:0045121 membrane raft(GO:0045121)
0.0 0.1 GO:1990075 periciliary membrane compartment(GO:1990075)
0.0 0.2 GO:0070552 BRISC complex(GO:0070552)
0.0 0.3 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.4 GO:0036038 MKS complex(GO:0036038)
0.0 0.1 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.9 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 1.8 GO:0030175 filopodium(GO:0030175)
0.0 0.2 GO:0030897 HOPS complex(GO:0030897)
0.0 0.4 GO:0005652 nuclear lamina(GO:0005652)
0.0 0.4 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.4 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.2 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 1.5 GO:0005884 actin filament(GO:0005884)
0.0 0.2 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.0 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.2 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.1 GO:0060091 kinocilium(GO:0060091)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 9.4 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.9 14.0 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.8 3.2 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.7 2.7 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.6 1.9 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.5 9.5 GO:0031996 thioesterase binding(GO:0031996)
0.5 4.0 GO:0046979 TAP2 binding(GO:0046979)
0.4 1.7 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.4 11.0 GO:0070628 proteasome binding(GO:0070628)
0.4 1.2 GO:0008457 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.4 6.5 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.2 2.8 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.2 2.1 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.2 11.7 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.2 3.2 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.2 6.6 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.2 0.6 GO:0051185 coenzyme transporter activity(GO:0051185)
0.1 0.4 GO:0004877 complement component C4b receptor activity(GO:0001861) complement component C3b receptor activity(GO:0004877)
0.1 3.7 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 0.4 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.1 2.1 GO:0050700 CARD domain binding(GO:0050700)
0.1 2.2 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.1 0.3 GO:0008480 sarcosine dehydrogenase activity(GO:0008480)
0.1 0.5 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.1 1.4 GO:0019957 C-C chemokine binding(GO:0019957)
0.1 0.5 GO:1990763 arrestin family protein binding(GO:1990763)
0.1 6.0 GO:0031593 polyubiquitin binding(GO:0031593)
0.1 1.3 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 0.9 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 1.5 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 0.4 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
0.1 1.8 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.1 1.4 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.1 0.9 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.1 0.4 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.1 1.1 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.1 0.5 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.1 0.4 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 0.3 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.1 0.4 GO:0031708 endothelin B receptor binding(GO:0031708)
0.1 0.3 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 0.6 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 1.0 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 0.5 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 4.3 GO:0032813 tumor necrosis factor receptor superfamily binding(GO:0032813)
0.1 0.4 GO:0005047 signal recognition particle binding(GO:0005047)
0.1 0.3 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
0.1 0.2 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.1 0.7 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 0.5 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.1 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.0 3.8 GO:0042805 actinin binding(GO:0042805)
0.0 1.4 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.4 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 6.5 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.2 GO:0001602 pancreatic polypeptide receptor activity(GO:0001602)
0.0 1.5 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.3 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.2 GO:0004127 cytidylate kinase activity(GO:0004127)
0.0 0.9 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.5 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.4 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.4 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.4 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.7 GO:0008391 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.1 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.0 0.1 GO:0031862 prostanoid receptor binding(GO:0031862)
0.0 0.7 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.7 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.0 0.6 GO:0005542 folic acid binding(GO:0005542)
0.0 1.1 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.5 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.3 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 4.7 GO:0000149 SNARE binding(GO:0000149)
0.0 0.9 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 0.5 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.4 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 2.1 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.8 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.7 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.9 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.1 GO:0015180 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858) azole transmembrane transporter activity(GO:1901474)
0.0 0.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.2 GO:0032190 manganese ion transmembrane transporter activity(GO:0005384) acrosin binding(GO:0032190)
0.0 1.1 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 3.9 GO:0004713 protein tyrosine kinase activity(GO:0004713)
0.0 0.2 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.3 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.2 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.0 0.2 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 2.5 GO:0019903 protein phosphatase binding(GO:0019903)
0.0 0.1 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.8 GO:0043022 ribosome binding(GO:0043022)
0.0 0.4 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 1.1 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.0 0.4 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.2 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.0 0.1 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.3 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.2 GO:0102391 decanoate--CoA ligase activity(GO:0102391)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 39.0 PID CD40 PATHWAY CD40/CD40L signaling
0.2 9.4 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.2 5.9 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.1 7.3 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.1 9.8 PID IL12 2PATHWAY IL12-mediated signaling events
0.1 4.0 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.1 4.1 ST G ALPHA I PATHWAY G alpha i Pathway
0.1 1.8 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 2.1 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.1 1.1 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 3.6 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.9 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.9 PID ARF 3PATHWAY Arf1 pathway
0.0 1.3 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 12.8 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 2.2 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.8 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 0.4 PID ENDOTHELIN PATHWAY Endothelins
0.0 0.3 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.5 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.3 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.2 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.7 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.6 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 6.5 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.5 5.4 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.4 21.2 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.4 8.0 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.2 5.5 REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.2 14.8 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.2 2.8 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.2 3.5 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 3.2 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 1.9 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.1 2.1 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.1 2.0 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.1 0.9 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.1 2.7 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 4.6 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.1 2.3 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.7 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.9 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.7 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 3.1 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.5 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 1.4 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 3.7 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 0.9 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.4 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.4 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.6 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 1.6 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.4 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.0 0.5 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 1.2 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.4 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.1 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.4 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.4 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism