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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for RFX3_RFX2

Z-value: 1.42

Motif logo

Transcription factors associated with RFX3_RFX2

Gene Symbol Gene ID Gene Info
ENSG00000080298.16 RFX3
ENSG00000087903.13 RFX2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RFX2hg38_v1_chr19_-_6110463_61105410.203.5e-01Click!
RFX3hg38_v1_chr9_-_3525968_3526017-0.164.3e-01Click!

Activity profile of RFX3_RFX2 motif

Sorted Z-values of RFX3_RFX2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of RFX3_RFX2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr5_-_150289941 8.02 ENST00000682786.1
calcium/calmodulin dependent protein kinase II alpha
chr5_-_150290093 6.08 ENST00000672479.1
calcium/calmodulin dependent protein kinase II alpha
chr5_-_150289764 5.50 ENST00000671881.1
ENST00000672752.1
ENST00000510347.2
ENST00000672829.1
ENST00000348628.11
calcium/calmodulin dependent protein kinase II alpha
chr5_-_150289625 4.63 ENST00000683332.1
ENST00000398376.8
ENST00000672785.1
ENST00000672396.1
calcium/calmodulin dependent protein kinase II alpha
chr13_-_43786889 1.96 ENST00000261488.10
ecto-NOX disulfide-thiol exchanger 1
chr22_+_23145366 1.70 ENST00000341989.9
ENST00000263116.8
RAB36, member RAS oncogene family
chr1_-_159900112 1.67 ENST00000479940.2
ENST00000368099.9
cilia and flagella associated protein 45
chr16_-_75556214 1.56 ENST00000568377.5
ENST00000565067.5
ENST00000258173.11
transmembrane protein 231
chr8_+_13566854 1.47 ENST00000297324.5
chromosome 8 open reading frame 48
chr5_-_180353317 1.46 ENST00000253778.13
glutamine-fructose-6-phosphate transaminase 2
chr13_+_36432487 1.32 ENST00000255465.7
ENST00000625767.1
cyclin A1
chr22_-_50307598 1.28 ENST00000425954.1
ENST00000449103.5
ENST00000359337.9
plexin B2
chr13_+_36431898 1.26 ENST00000440264.5
cyclin A1
chr20_-_45912047 1.21 ENST00000477313.5
ENST00000354050.8
ENST00000372431.8
ENST00000420868.2
phospholipid transfer protein
chr10_+_12349533 1.20 ENST00000619168.5
calcium/calmodulin dependent protein kinase ID
chr15_+_90184912 1.19 ENST00000561085.1
ENST00000332496.10
semaphorin 4B
chr3_-_58577367 1.18 ENST00000464064.5
ENST00000360997.7
family with sequence similarity 107 member A
chr1_-_36450410 1.18 ENST00000356637.9
ENST00000354267.3
ENST00000235532.9
organic solute carrier partner 1
chr19_-_7488966 1.17 ENST00000593547.1
peroxisomal biogenesis factor 11 gamma
chr2_+_231198546 1.17 ENST00000349938.8
ENST00000682334.1
ENST00000682002.1
ENST00000683275.1
ENST00000611582.5
ENST00000436339.6
ENST00000683271.1
ENST00000440107.6
ENST00000684432.1
ENST00000682100.1
ENST00000682367.1
ENST00000683112.1
ENST00000682030.1
ENST00000684718.1
ENST00000683553.1
ENST00000683966.1
ENST00000683575.1
armadillo repeat containing 9
chr19_-_633500 1.15 ENST00000588649.7
RNA polymerase mitochondrial
chr6_-_112087451 1.14 ENST00000368662.10
tubulin epsilon 1
chr7_-_103074816 1.11 ENST00000379305.7
ENST00000379308.7
F-box and leucine rich repeat protein 13
chr5_-_14011743 1.09 ENST00000681290.1
dynein axonemal heavy chain 5
chr3_-_58577648 1.09 ENST00000394481.5
family with sequence similarity 107 member A
chr17_+_42798779 1.07 ENST00000585355.5
cyclin N-terminal domain containing 1
chr19_-_7489003 1.07 ENST00000221480.6
peroxisomal biogenesis factor 11 gamma
chr6_+_109440695 1.06 ENST00000258052.8
sphingomyelin phosphodiesterase 2
chr14_+_32329256 1.06 ENST00000280979.9
A-kinase anchoring protein 6
chr10_-_25016105 1.06 ENST00000376363.5
ENST00000331161.9
enkurin, TRPC channel interacting protein
chr4_-_176195563 1.05 ENST00000280191.7
spermatogenesis associated 4
chr21_+_42499600 1.02 ENST00000398341.7
solute carrier family 37 member 1
chr17_+_7717727 1.02 ENST00000570791.5
dynein axonemal heavy chain 2
chr17_-_62808339 1.01 ENST00000583600.5
membrane associated ring-CH-type finger 10
chr17_+_42980547 1.00 ENST00000361677.5
ENST00000589705.1
RUN domain containing 1
chr16_+_57639518 0.99 ENST00000540164.6
ENST00000568531.5
adhesion G protein-coupled receptor G1
chr1_-_37859583 0.98 ENST00000373036.5
metal regulatory transcription factor 1
chr17_-_62808299 0.98 ENST00000311269.10
membrane associated ring-CH-type finger 10
chr16_+_57372481 0.97 ENST00000006053.7
C-X3-C motif chemokine ligand 1
chr18_+_34818436 0.97 ENST00000599844.5
ENST00000679731.1
dystrobrevin alpha
chr12_+_78036248 0.96 ENST00000644176.1
neuron navigator 3
chr19_+_10106688 0.95 ENST00000430370.1
peter pan homolog
chr11_+_134331874 0.93 ENST00000339772.9
ENST00000535456.7
galactosidase beta 1 like 2
chr22_-_37844308 0.90 ENST00000411961.6
ENST00000434930.1
ENST00000215941.9
ankyrin repeat domain 54
chr9_+_94084458 0.90 ENST00000620992.5
ENST00000288976.3
protein tyrosine phosphatase domain containing 1
chr8_+_42152946 0.89 ENST00000518421.5
ENST00000174653.3
ENST00000396926.8
ENST00000521280.5
ENST00000522288.5
adaptor related protein complex 3 subunit mu 2
chr8_+_22604632 0.88 ENST00000308511.8
ENST00000523801.5
ENST00000521301.5
cell cycle and apoptosis regulator 2
chr19_+_10106592 0.87 ENST00000446223.5
peter pan homolog
chr8_+_22605018 0.85 ENST00000389279.7
cell cycle and apoptosis regulator 2
chr8_+_144477975 0.84 ENST00000435887.2
protein phosphatase 1 regulatory subunit 16A
chr15_+_70892443 0.82 ENST00000443425.6
ENST00000560369.5
leucine rich repeat containing 49
chr1_-_58784035 0.81 ENST00000371222.4
Jun proto-oncogene, AP-1 transcription factor subunit
chr19_-_50514624 0.81 ENST00000601207.5
ENST00000598657.1
ENST00000376916.7
aspartate dehydrogenase domain containing
chr20_+_3888915 0.81 ENST00000316562.9
ENST00000495692.5
pantothenate kinase 2
chr14_-_73950075 0.80 ENST00000286544.5
FAM161 centrosomal protein B
chr22_-_38656353 0.79 ENST00000535113.7
family with sequence similarity 227 member A
chr15_-_82262660 0.79 ENST00000557844.1
ENST00000359445.7
ENST00000268206.12
elongation factor like GTPase 1
chr1_+_155208727 0.78 ENST00000316721.8
metaxin 1
chr1_+_155208690 0.78 ENST00000368376.8
metaxin 1
chr16_+_30762289 0.78 ENST00000566811.5
ENST00000565995.5
ENST00000563683.5
ENST00000357890.9
ENST00000324685.11
ENST00000565931.1
ring finger protein 40
chr15_+_70892809 0.77 ENST00000260382.10
ENST00000560755.5
leucine rich repeat containing 49
chr2_-_26641363 0.76 ENST00000288861.5
calcium and integrin binding family member 4
chr18_+_34710307 0.75 ENST00000679796.1
dystrobrevin alpha
chr6_-_32178080 0.75 ENST00000336984.6
1-acylglycerol-3-phosphate O-acyltransferase 1
chr1_+_156150008 0.75 ENST00000355014.6
semaphorin 4A
chr7_-_140640776 0.75 ENST00000275884.10
ENST00000475837.1
ENST00000496613.6
DENN domain containing 2A
chr17_+_40219276 0.75 ENST00000583268.1
ENST00000323571.9
WAS/WASL interacting protein family member 2
chr22_+_37051787 0.74 ENST00000456470.1
potassium channel tetramerization domain containing 17
chr22_+_37051731 0.74 ENST00000610767.4
ENST00000402077.7
ENST00000403888.7
potassium channel tetramerization domain containing 17
chr14_-_76812804 0.73 ENST00000556298.1
ENST00000251089.8
angel homolog 1
chr8_+_38386303 0.73 ENST00000519476.6
leucine zipper and EF-hand containing transmembrane protein 2
chr8_+_119416427 0.71 ENST00000259526.4
cellular communication network factor 3
chr17_-_6640653 0.71 ENST00000571642.5
ENST00000361413.8
ENST00000572370.5
KIAA0753
chr11_-_65117639 0.70 ENST00000528598.1
ENST00000310597.6
zinc finger HIT-type containing 2
chr16_+_57628507 0.70 ENST00000456916.5
ENST00000567154.5
ENST00000388813.9
ENST00000562558.6
ENST00000566271.6
ENST00000563374.5
ENST00000673126.2
ENST00000562631.7
ENST00000568234.5
ENST00000565770.5
ENST00000566164.5
adhesion G protein-coupled receptor G1
chr1_+_161098320 0.69 ENST00000368011.9
ENST00000392192.6
kelch domain containing 9
chr6_+_52420107 0.68 ENST00000636489.1
ENST00000637089.1
ENST00000637353.1
ENST00000637263.1
EF-hand domain containing 1
chr1_-_52033772 0.68 ENST00000371614.2
KTI12 chromatin associated homolog
chr2_-_74421560 0.67 ENST00000612891.4
ENST00000640331.1
ENST00000684111.1
chromosome 2 open reading frame 81
chr1_-_231241090 0.67 ENST00000451322.1
chromosome 1 open reading frame 131
chr16_+_57639295 0.67 ENST00000564783.5
ENST00000564729.5
ENST00000565976.6
ENST00000566508.5
adhesion G protein-coupled receptor G1
chr2_+_202073282 0.66 ENST00000459709.5
KIAA2012
chr20_+_63272847 0.66 ENST00000518601.6
ENST00000353546.7
ADP ribosylation factor GTPase activating protein 1
chr20_+_63272785 0.66 ENST00000519273.6
ENST00000519604.5
ENST00000523114.5
ENST00000547204.5
ENST00000549047.5
ENST00000523460.5
ENST00000370283.9
ENST00000370275.8
ADP ribosylation factor GTPase activating protein 1
chr17_+_7355123 0.66 ENST00000389982.8
ENST00000576060.6
ENST00000330767.4
transmembrane protein 95
chr2_+_202073249 0.64 ENST00000498697.3
KIAA2012
chr11_-_8810635 0.64 ENST00000527510.5
ENST00000528527.5
ENST00000313726.11
ENST00000528523.5
DENN domain containing 2B
chr7_-_4883683 0.63 ENST00000399583.4
Rap associating with DIL domain
chr6_-_152563271 0.62 ENST00000535896.7
ENST00000672122.1
spectrin repeat containing nuclear envelope protein 1
chr16_+_57372465 0.62 ENST00000563383.1
C-X3-C motif chemokine ligand 1
chr7_+_100101632 0.62 ENST00000359593.9
adaptor related protein complex 4 subunit mu 1
chr1_-_222589898 0.62 ENST00000350027.8
ENST00000352967.9
TATA-box binding protein associated factor, RNA polymerase I subunit A
chr11_-_64778747 0.61 ENST00000227503.13
ENST00000377394.7
ENST00000334944.9
splicing factor 1
chr13_+_23979794 0.61 ENST00000424834.6
ENST00000439928.2
spermatogenesis associated 13
spermatogenesis associated 13
chr19_-_4535221 0.61 ENST00000381848.7
ENST00000586133.1
perilipin 5
chr3_-_27369355 0.61 ENST00000429845.6
ENST00000341435.9
ENST00000435750.1
NIMA related kinase 10
chr19_+_10106398 0.61 ENST00000393793.5
peter pan homolog
chr1_+_15409858 0.61 ENST00000375980.9
EF-hand domain family member D2
chr11_-_57322197 0.61 ENST00000532437.1
tankyrase 1 binding protein 1
chr3_+_48466222 0.61 ENST00000625293.3
ENST00000492235.2
ENST00000635452.2
ENST00000456089.1
three prime repair exonuclease 1
chr3_+_48465811 0.61 ENST00000433541.1
ENST00000444177.1
three prime repair exonuclease 1
chr1_-_222589759 0.60 ENST00000391883.2
ENST00000366890.5
TATA-box binding protein associated factor, RNA polymerase I subunit A
chr2_+_26848199 0.60 ENST00000401478.5
dihydropyrimidinase like 5
chr14_-_59465327 0.60 ENST00000395116.1
G protein-coupled receptor 135
chr12_+_6821797 0.60 ENST00000311268.8
ENST00000382315.7
G protein-coupled receptor 162
chr15_+_97960692 0.59 ENST00000268042.7
arrestin domain containing 4
chr1_+_203475798 0.59 ENST00000343110.3
proline and arginine rich end leucine rich repeat protein
chr19_-_46746421 0.59 ENST00000263280.11
striatin 4
chr12_-_25195074 0.58 ENST00000354189.9
ENST00000676236.1
ENST00000545133.5
ENST00000554347.1
ENST00000674567.1
ENST00000395987.8
ENST00000320267.13
ENST00000395990.6
cilia and flagella associated protein 94
chr16_+_84145256 0.58 ENST00000378553.10
dynein axonemal assembly factor 1
chr16_+_67806765 0.58 ENST00000415766.7
ENST00000561639.6
translin associated factor X interacting protein 1
chr16_+_57628684 0.58 ENST00000567397.5
ENST00000568979.5
ENST00000672974.1
adhesion G protein-coupled receptor G1
chr3_-_74521140 0.57 ENST00000263665.6
contactin 3
chr19_+_35139440 0.57 ENST00000455515.6
FXYD domain containing ion transport regulator 1
chr12_-_119804298 0.56 ENST00000678652.1
ENST00000678494.1
citron rho-interacting serine/threonine kinase
chr19_-_49867542 0.56 ENST00000600910.5
ENST00000322344.8
ENST00000600573.5
ENST00000596726.3
ENST00000638016.1
polynucleotide kinase 3'-phosphatase
chr22_+_38057200 0.55 ENST00000404072.7
ENST00000424694.5
protein interacting with PRKCA 1
chr5_+_122845488 0.55 ENST00000513881.5
sorting nexin 24
chr19_+_55339867 0.55 ENST00000255613.8
lysine methyltransferase 5C
chr6_-_5260883 0.53 ENST00000330636.9
LYR motif containing 4
chr19_-_49867251 0.53 ENST00000631020.2
ENST00000596014.5
ENST00000636994.1
polynucleotide kinase 3'-phosphatase
chr5_+_141051374 0.52 ENST00000306549.6
protocadherin beta 1
chr1_-_183653307 0.52 ENST00000308641.6
apolipoprotein B mRNA editing enzyme catalytic polypeptide like 4
chr10_+_125896549 0.52 ENST00000368693.6
fibronectin type III and ankyrin repeat domains 1
chr14_-_24188787 0.51 ENST00000625289.1
ENST00000354464.11
importin 4
chr22_-_18024513 0.51 ENST00000441493.7
microtubule associated monooxygenase, calponin and LIM domain containing 3
chr7_+_100101556 0.51 ENST00000438383.5
ENST00000429084.5
ENST00000439416.5
adaptor related protein complex 4 subunit mu 1
chr19_+_35139724 0.51 ENST00000588715.5
ENST00000588607.5
FXYD domain containing ion transport regulator 1
chr2_-_202871253 0.51 ENST00000435143.5
islet cell autoantigen 1 like
chr22_+_38057371 0.51 ENST00000437453.5
ENST00000356976.8
protein interacting with PRKCA 1
chr12_-_119804472 0.51 ENST00000678087.1
ENST00000677993.1
citron rho-interacting serine/threonine kinase
chr17_-_45317006 0.51 ENST00000344686.8
ENST00000617331.3
mitogen-activated protein kinase kinase kinase 14
chr19_-_55279690 0.51 ENST00000587959.1
ENST00000585927.1
ENST00000587922.5
ENST00000585698.1
HSPA (Hsp70) binding protein 1
chr1_-_74198132 0.51 ENST00000370911.7
ENST00000370909.6
ENST00000354431.9
leucine rich repeats and IQ motif containing 3
chr19_+_35138993 0.51 ENST00000612146.4
ENST00000589209.5
FXYD domain containing ion transport regulator 1
chr19_-_55280194 0.50 ENST00000588971.1
ENST00000255631.9
ENST00000587551.1
HSPA (Hsp70) binding protein 1
chr17_-_42980393 0.49 ENST00000409446.8
ENST00000409399.6
ENST00000421990.7
prostaglandin E synthase 3 like
PTGES3L-AARSD1 readthrough
chr8_+_38386433 0.49 ENST00000297720.9
ENST00000524874.5
ENST00000379957.9
ENST00000523983.6
leucine zipper and EF-hand containing transmembrane protein 2
chr14_+_32329341 0.49 ENST00000557354.5
ENST00000557102.1
ENST00000557272.1
A-kinase anchoring protein 6
chr8_-_143541425 0.49 ENST00000262577.6
zinc finger CCCH-type containing 3
chr14_-_70080180 0.49 ENST00000394330.6
ENST00000533541.1
ENST00000216568.11
solute carrier family 8 member A3
chr2_-_9630946 0.48 ENST00000446619.1
ENST00000238081.8
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
chr16_-_57802401 0.48 ENST00000569112.5
ENST00000445690.7
ENST00000562311.5
ENST00000379655.8
kinesin family member C3
chr11_-_112074239 0.48 ENST00000530641.5
PIH1 domain containing 2
chr8_+_144095054 0.48 ENST00000318911.5
cytochrome c1
chr16_+_67807082 0.48 ENST00000567852.5
ENST00000565148.5
ENST00000388833.7
ENST00000561654.5
ENST00000431934.2
translin associated factor X interacting protein 1
chr21_-_36060300 0.48 ENST00000442559.5
ENST00000399205.5
ENST00000429161.5
ENST00000424303.5
ENST00000399208.6
SET domain containing 4
chr6_-_39725335 0.48 ENST00000538893.5
kinesin family member 6
chr14_-_73950393 0.48 ENST00000651776.1
FAM161 centrosomal protein B
chr20_-_49915509 0.48 ENST00000289431.10
spermatogenesis associated 2
chr19_-_18397596 0.48 ENST00000595840.1
ENST00000339007.4
leucine rich repeat containing 25
chr8_-_97277890 0.48 ENST00000322128.5
TSPY like 5
chr5_+_122845584 0.47 ENST00000395451.8
ENST00000261369.9
ENST00000506996.5
sorting nexin 24
chr19_-_50513870 0.47 ENST00000389208.9
aspartate dehydrogenase domain containing
chr19_-_55280063 0.47 ENST00000593263.5
ENST00000433386.7
HSPA (Hsp70) binding protein 1
chr4_-_75630473 0.47 ENST00000307465.9
cyclin dependent kinase like 2
chr15_-_67254625 0.47 ENST00000261880.10
ENST00000561452.5
alpha and gamma adaptin binding protein
chr19_+_2785481 0.47 ENST00000307741.11
ENST00000585338.1
thimet oligopeptidase 1
chr10_+_25016596 0.46 ENST00000376356.5
ENST00000524413.5
threonine synthase like 1
chr19_+_58467045 0.46 ENST00000535298.5
ENST00000536459.6
ENST00000196482.4
zinc finger protein 324
chr4_+_122732652 0.46 ENST00000542236.5
ENST00000314218.8
Bardet-Biedl syndrome 12
chr11_-_75668434 0.46 ENST00000434603.2
microtubule associated protein 6
chr9_-_114348966 0.46 ENST00000374079.8
AT-hook transcription factor
chr19_+_35140022 0.45 ENST00000588081.5
ENST00000589121.1
FXYD domain containing ion transport regulator 1
chr17_-_42979993 0.45 ENST00000409103.5
ENST00000360221.8
ENST00000454303.1
ENST00000591916.7
ENST00000451885.3
PTGES3L-AARSD1 readthrough
prostaglandin E synthase 3 like
chr19_-_19618667 0.45 ENST00000251203.14
PBX homeobox 4
chr9_-_136118850 0.45 ENST00000418388.6
transmembrane protein 250
chr1_+_209686173 0.45 ENST00000615289.4
ENST00000367028.6
ENST00000261465.5
hydroxysteroid 11-beta dehydrogenase 1
chr19_+_10106223 0.45 ENST00000428358.5
PPAN-P2RY11 readthrough
chr19_-_50025327 0.44 ENST00000594092.5
ENST00000594948.5
ENST00000316763.8
ENST00000377011.6
ENST00000593919.5
ENST00000601324.1
ENST00000601341.5
ENST00000600259.5
VRK serine/threonine kinase 3
chr12_-_113471851 0.44 ENST00000261731.4
LIM homeobox 5
chr6_+_52420332 0.44 ENST00000636107.1
ENST00000371068.11
ENST00000636702.1
ENST00000635996.1
ENST00000636379.1
EF-hand domain containing 1
chr11_+_8019193 0.44 ENST00000534099.5
TUB bipartite transcription factor
chr2_-_10448318 0.44 ENST00000234111.9
ornithine decarboxylase 1
chr18_+_34710249 0.44 ENST00000680346.1
ENST00000348997.9
ENST00000681274.1
ENST00000680822.1
ENST00000680767.2
ENST00000597599.5
ENST00000444659.6
dystrobrevin alpha
chr19_+_10106320 0.44 ENST00000253107.12
ENST00000393796.4
peter pan homolog
PPAN-P2RY11 readthrough
chr2_+_48314637 0.44 ENST00000413569.5
ENST00000340553.8
forkhead box N2
chrX_-_107206426 0.43 ENST00000372466.8
ENST00000421752.1
nucleoporin 62 C-terminal like
chr7_-_44325490 0.43 ENST00000350811.7
calcium/calmodulin dependent protein kinase II beta
chr17_-_17281232 0.43 ENST00000417352.5
ENST00000268717.10
COP9 signalosome subunit 3
chr12_-_1594568 0.43 ENST00000339235.4
F-box and leucine rich repeat protein 14
chr3_-_14124816 0.43 ENST00000295767.9
ENST00000396914.4
coiled-coil-helix-coiled-coil-helix domain containing 4
chr11_+_31369834 0.43 ENST00000465995.6
DnaJ heat shock protein family (Hsp40) member C24
chr4_-_152779710 0.42 ENST00000304337.3
tigger transposable element derived 4
chr16_+_3500964 0.42 ENST00000574369.5
ENST00000576634.6
ENST00000341633.9
ENST00000571025.5
clusterin associated protein 1
chr3_-_119034810 0.41 ENST00000393775.7
immunoglobulin superfamily member 11
chr20_+_50510321 0.41 ENST00000541713.5
ENST00000371621.5
protein tyrosine phosphatase non-receptor type 1
chr7_+_100101657 0.41 ENST00000421755.5
adaptor related protein complex 4 subunit mu 1
chr17_+_44004604 0.41 ENST00000293404.8
ENST00000589767.1
N-acetylglutamate synthase
chr15_+_41774459 0.41 ENST00000457542.7
ENST00000456763.6
mitogen-activated protein kinase binding protein 1
chr19_-_48511793 0.40 ENST00000600059.6
lemur tyrosine kinase 3
chr19_+_38289138 0.40 ENST00000590738.1
ENST00000587519.4
ENST00000591889.2
serine peptidase inhibitor, Kunitz type 2
novel protein
chr15_-_84654270 0.40 ENST00000434634.7
WD repeat domain 73
chr15_+_55408479 0.40 ENST00000569691.2
chromosome 15 open reading frame 65
chr6_-_30672984 0.40 ENST00000415603.1
ENST00000376442.8
DEAH-box helicase 16
chr5_-_147782518 0.40 ENST00000507386.5
janus kinase and microtubule interacting protein 2
chr16_-_30010972 0.40 ENST00000565273.5
ENST00000567332.6
ENST00000350119.9
double C2 domain alpha
chr16_+_30053123 0.40 ENST00000395248.6
ENST00000575627.5
ENST00000566897.6
ENST00000568435.6
ENST00000338110.11
ENST00000562240.1
novel protein
chr21_-_36060242 0.39 ENST00000443703.1
ENST00000399207.5
ENST00000399215.5
SET domain containing 4
chr15_+_43510945 0.39 ENST00000382031.5
microtubule associated protein 1A

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 24.2 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.5 1.6 GO:0051040 regulation of calcium-independent cell-cell adhesion(GO:0051040)
0.4 1.3 GO:0019364 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.4 1.1 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.3 2.0 GO:0010731 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.3 0.8 GO:0035026 leading edge cell differentiation(GO:0035026) cellular response to potassium ion starvation(GO:0051365)
0.2 1.2 GO:0042360 vitamin E metabolic process(GO:0042360)
0.2 1.5 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.2 1.1 GO:0010836 negative regulation of protein ADP-ribosylation(GO:0010836)
0.2 0.6 GO:0031393 negative regulation of prostaglandin biosynthetic process(GO:0031393)
0.2 0.8 GO:2001168 regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.2 0.6 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.2 1.5 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.2 2.9 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.1 1.2 GO:0044375 regulation of peroxisome size(GO:0044375)
0.1 0.4 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.1 0.4 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
0.1 0.4 GO:2000646 positive regulation of receptor catabolic process(GO:2000646)
0.1 0.1 GO:0003352 regulation of cilium movement(GO:0003352) regulation of cilium beat frequency(GO:0003356)
0.1 1.2 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.1 1.1 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.1 0.5 GO:0007113 endomitotic cell cycle(GO:0007113)
0.1 1.0 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1 0.6 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.1 0.6 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.1 0.8 GO:1904100 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.1 0.3 GO:0018874 benzoate metabolic process(GO:0018874)
0.1 0.3 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.1 1.7 GO:1901978 positive regulation of cell cycle checkpoint(GO:1901978)
0.1 0.4 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.1 2.0 GO:0021670 lateral ventricle development(GO:0021670)
0.1 0.5 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.1 0.8 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.1 0.3 GO:0014740 negative regulation of muscle hyperplasia(GO:0014740)
0.1 0.3 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.1 0.4 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.1 1.1 GO:0015939 pantothenate metabolic process(GO:0015939)
0.1 0.3 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.1 1.5 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.1 0.3 GO:0000915 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.1 0.4 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.1 0.3 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.1 0.5 GO:0045218 zonula adherens maintenance(GO:0045218)
0.1 0.2 GO:0014016 proximal/distal axis specification(GO:0009946) neuroblast differentiation(GO:0014016)
0.1 0.4 GO:0030860 regulation of polarized epithelial cell differentiation(GO:0030860)
0.1 3.2 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.1 0.2 GO:0045014 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.1 0.2 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.1 0.4 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
0.1 0.2 GO:0036451 cap mRNA methylation(GO:0036451)
0.1 0.4 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.1 0.2 GO:0014028 notochord formation(GO:0014028)
0.1 2.6 GO:0007141 male meiosis I(GO:0007141)
0.1 0.5 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.1 0.2 GO:0090149 mitochondrial membrane fission(GO:0090149)
0.1 0.3 GO:1904637 response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
0.1 1.2 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.1 0.6 GO:2000210 positive regulation of anoikis(GO:2000210)
0.1 1.4 GO:0090154 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.1 0.4 GO:0021937 cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
0.1 0.3 GO:1904398 positive regulation of neuromuscular junction development(GO:1904398)
0.1 0.5 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.1 0.5 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 0.6 GO:0043578 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1 0.3 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.1 0.2 GO:1901355 response to rapamycin(GO:1901355)
0.1 0.5 GO:0032264 IMP salvage(GO:0032264)
0.1 0.3 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.1 0.6 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1 0.2 GO:1902490 regulation of sperm capacitation(GO:1902490)
0.0 0.4 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.0 0.5 GO:1990034 calcium ion export from cell(GO:1990034)
0.0 0.2 GO:0000432 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432)
0.0 0.2 GO:2000382 positive regulation of mesoderm development(GO:2000382)
0.0 0.4 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
0.0 0.1 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.0 0.4 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.1 GO:0031587 positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587)
0.0 2.4 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.2 GO:1901526 positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.0 0.4 GO:0006526 arginine biosynthetic process(GO:0006526)
0.0 0.2 GO:0080154 regulation of fertilization(GO:0080154)
0.0 1.2 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.0 0.2 GO:0030806 negative regulation of cyclic nucleotide catabolic process(GO:0030806) negative regulation of cAMP catabolic process(GO:0030821)
0.0 0.2 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 0.2 GO:0021513 spinal cord dorsal/ventral patterning(GO:0021513)
0.0 0.5 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.2 GO:0099542 trans-synaptic signaling by lipid(GO:0099541) trans-synaptic signaling by endocannabinoid(GO:0099542)
0.0 0.2 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.0 0.2 GO:0006591 ornithine metabolic process(GO:0006591)
0.0 0.1 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.0 1.0 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.4 GO:0042256 mature ribosome assembly(GO:0042256)
0.0 0.1 GO:1990262 regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
0.0 0.2 GO:0007000 nucleolus organization(GO:0007000)
0.0 2.2 GO:0042073 intraciliary transport(GO:0042073)
0.0 0.8 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 1.1 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.0 0.3 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.0 1.6 GO:0007131 reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.0 0.2 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.1 GO:0071955 recycling endosome to Golgi transport(GO:0071955)
0.0 0.2 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.0 0.2 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324)
0.0 0.8 GO:0060285 cilium-dependent cell motility(GO:0060285)
0.0 0.3 GO:0036371 protein localization to T-tubule(GO:0036371)
0.0 0.1 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.0 0.7 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0 0.8 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.1 GO:0035744 T-helper 1 cell cytokine production(GO:0035744)
0.0 0.1 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.1 GO:0070898 RNA polymerase III transcriptional preinitiation complex assembly(GO:0070898)
0.0 0.3 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 1.2 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.0 0.3 GO:0045657 positive regulation of monocyte differentiation(GO:0045657)
0.0 0.1 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.0 0.1 GO:0071043 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0 0.2 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.0 1.3 GO:0050919 negative chemotaxis(GO:0050919)
0.0 1.4 GO:0006298 mismatch repair(GO:0006298)
0.0 0.6 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.0 0.7 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 0.1 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.0 0.3 GO:0060681 branch elongation involved in ureteric bud branching(GO:0060681)
0.0 0.3 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.0 1.3 GO:2001222 regulation of neuron migration(GO:2001222)
0.0 0.1 GO:0030581 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0 0.3 GO:1900864 mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.0 0.2 GO:0061009 common bile duct development(GO:0061009)
0.0 0.1 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0 0.3 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.3 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.0 0.2 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.0 0.5 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
0.0 0.1 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.0 0.2 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 1.1 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.1 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.0 0.4 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.0 0.2 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.1 GO:0006864 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.0 0.6 GO:0014733 regulation of skeletal muscle adaptation(GO:0014733)
0.0 0.9 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.0 1.2 GO:0021795 cerebral cortex cell migration(GO:0021795)
0.0 0.4 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0 0.3 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.3 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.2 GO:0051014 actin filament severing(GO:0051014)
0.0 3.8 GO:0006626 protein targeting to mitochondrion(GO:0006626)
0.0 0.1 GO:0001757 somite specification(GO:0001757) floor plate development(GO:0033504)
0.0 0.3 GO:0035278 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.6 GO:0048665 neuron fate specification(GO:0048665)
0.0 0.3 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.1 GO:0001302 replicative cell aging(GO:0001302)
0.0 0.2 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 1.4 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.4 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
0.0 0.4 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0 0.1 GO:1902361 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.0 0.1 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 1.4 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.0 0.3 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.0 0.1 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.2 GO:0042407 cristae formation(GO:0042407)
0.0 0.8 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.1 GO:0031937 positive regulation of chromatin silencing(GO:0031937)
0.0 0.3 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.1 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.0 0.3 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 0.3 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 0.2 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.1 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.0 0.1 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.0 GO:0006532 aspartate biosynthetic process(GO:0006532)
0.0 0.5 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 0.1 GO:0072520 seminiferous tubule development(GO:0072520)
0.0 0.3 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 0.6 GO:0021762 substantia nigra development(GO:0021762)
0.0 0.1 GO:0000012 single strand break repair(GO:0000012)
0.0 1.3 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0 0.1 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.1 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 0.3 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.2 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.0 GO:0030573 bile acid catabolic process(GO:0030573)
0.0 0.1 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.2 GO:0043320 natural killer cell degranulation(GO:0043320)
0.0 0.2 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.4 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.0 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.0 0.4 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.6 GO:0006400 tRNA modification(GO:0006400)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.6 GO:0097123 cyclin A1-CDK2 complex(GO:0097123)
0.6 1.7 GO:0044609 DBIRD complex(GO:0044609)
0.4 3.0 GO:0097451 glial limiting end-foot(GO:0097451)
0.2 1.2 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.2 0.6 GO:1990716 axonemal central apparatus(GO:1990716)
0.2 1.5 GO:0000138 Golgi trans cisterna(GO:0000138)
0.2 0.2 GO:0097598 sperm cytoplasmic droplet(GO:0097598)
0.1 22.0 GO:0042734 presynaptic membrane(GO:0042734)
0.1 2.2 GO:0005858 axonemal dynein complex(GO:0005858)
0.1 1.5 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.1 4.1 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.1 2.6 GO:0036038 MKS complex(GO:0036038)
0.1 0.8 GO:0033503 HULC complex(GO:0033503)
0.1 0.8 GO:0035976 AP1 complex(GO:0035976)
0.1 1.9 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 0.3 GO:0016939 kinesin II complex(GO:0016939)
0.1 1.8 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 0.3 GO:0097149 centralspindlin complex(GO:0097149)
0.1 0.3 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.1 0.3 GO:0044214 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.0 0.2 GO:1990032 parallel fiber(GO:1990032)
0.0 0.4 GO:0097443 sorting endosome(GO:0097443)
0.0 0.3 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.0 0.7 GO:0035869 ciliary transition zone(GO:0035869)
0.0 0.3 GO:0034448 EGO complex(GO:0034448)
0.0 0.2 GO:0043291 RAVE complex(GO:0043291)
0.0 0.4 GO:0036128 CatSper complex(GO:0036128)
0.0 1.2 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.6 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.5 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.2 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.5 GO:0005915 zonula adherens(GO:0005915)
0.0 0.3 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.5 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.5 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.3 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.7 GO:0036020 endolysosome membrane(GO:0036020)
0.0 0.3 GO:0005638 lamin filament(GO:0005638)
0.0 1.6 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.2 GO:0061617 MICOS complex(GO:0061617)
0.0 1.0 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.6 GO:0000242 pericentriolar material(GO:0000242)
0.0 1.5 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.1 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.0 1.1 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.8 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.5 GO:0001741 XY body(GO:0001741)
0.0 0.1 GO:1990031 pinceau fiber(GO:1990031)
0.0 0.4 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.0 0.1 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.0 0.2 GO:0043196 varicosity(GO:0043196)
0.0 0.2 GO:0016589 NURF complex(GO:0016589)
0.0 1.8 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.2 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.3 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.3 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.2 GO:0030897 HOPS complex(GO:0030897)
0.0 0.6 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.2 GO:0016342 catenin complex(GO:0016342)
0.0 0.2 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.0 0.8 GO:0016235 aggresome(GO:0016235)
0.0 0.1 GO:1990769 proximal neuron projection(GO:1990769)
0.0 0.2 GO:0032059 bleb(GO:0032059)
0.0 0.0 GO:0097545 axonemal outer doublet(GO:0097545)
0.0 0.4 GO:0070822 Sin3-type complex(GO:0070822)
0.0 0.5 GO:0000791 euchromatin(GO:0000791)
0.0 0.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.2 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.2 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.3 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.2 GO:0005869 dynactin complex(GO:0005869)
0.0 3.3 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.2 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.6 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.1 GO:0005787 signal peptidase complex(GO:0005787)
0.0 1.1 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 1.5 GO:0005814 centriole(GO:0005814)
0.0 0.2 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.2 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.1 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.1 GO:0034709 methylosome(GO:0034709)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 24.3 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.4 1.3 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.4 1.5 GO:0004360 glutamine-fructose-6-phosphate transaminase (isomerizing) activity(GO:0004360)
0.3 1.1 GO:0051733 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.2 1.0 GO:0015526 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.2 0.6 GO:0031862 prostanoid receptor binding(GO:0031862)
0.2 1.2 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.2 1.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.2 0.6 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.1 0.4 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.1 0.5 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.1 0.8 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 1.4 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 0.6 GO:0070568 guanylyltransferase activity(GO:0070568)
0.1 0.5 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.1 2.3 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.1 0.9 GO:0004565 beta-galactosidase activity(GO:0004565)
0.1 0.6 GO:0035473 lipase binding(GO:0035473)
0.1 0.4 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.1 1.1 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 1.5 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 0.6 GO:0008158 hedgehog receptor activity(GO:0008158)
0.1 0.6 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 0.2 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.1 0.4 GO:0004370 glycerol kinase activity(GO:0004370)
0.1 0.2 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.1 0.3 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
0.1 0.2 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.1 1.5 GO:0097602 cullin family protein binding(GO:0097602)
0.1 1.0 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 0.5 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.5 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.1 0.5 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.1 0.5 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.1 1.3 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.4 GO:1904288 BAT3 complex binding(GO:1904288)
0.1 0.2 GO:0015489 polyamine transmembrane transporter activity(GO:0015203) putrescine transmembrane transporter activity(GO:0015489)
0.0 0.1 GO:0070984 SET domain binding(GO:0070984)
0.0 0.3 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0 1.8 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.3 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0 0.4 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.8 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.2 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.0 0.1 GO:0033699 DNA 5'-adenosine monophosphate hydrolase activity(GO:0033699)
0.0 1.2 GO:0071949 FAD binding(GO:0071949)
0.0 1.3 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.0 1.9 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.9 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.3 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 1.6 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.1 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.0 0.5 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.1 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.0 3.3 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.2 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.8 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.3 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.4 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.3 GO:0019826 oxygen sensor activity(GO:0019826)
0.0 0.1 GO:0030156 benzodiazepine receptor binding(GO:0030156)
0.0 0.1 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.0 2.3 GO:0043022 ribosome binding(GO:0043022)
0.0 0.3 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.0 0.6 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.2 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.1 GO:0050211 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823) procollagen galactosyltransferase activity(GO:0050211)
0.0 0.6 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.7 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 1.9 GO:0019843 rRNA binding(GO:0019843)
0.0 0.2 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.1 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.0 0.1 GO:0002046 opsin binding(GO:0002046)
0.0 0.1 GO:0032406 MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408)
0.0 0.8 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.2 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.0 0.8 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 1.0 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.4 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.1 GO:0052839 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.0 0.5 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.4 GO:0005522 profilin binding(GO:0005522)
0.0 0.6 GO:0005521 lamin binding(GO:0005521)
0.0 0.1 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.0 1.0 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.0 0.2 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 1.3 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 1.0 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.2 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.5 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 0.3 GO:0070513 death domain binding(GO:0070513)
0.0 0.7 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.6 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.0 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.0 0.3 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.4 GO:0008198 ferrous iron binding(GO:0008198)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.2 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.2 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.8 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.2 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.0 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.0 1.8 GO:0005254 chloride channel activity(GO:0005254)
0.0 0.1 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.0 0.3 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.4 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.2 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.1 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 0.3 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.5 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.2 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.4 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.1 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.3 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 2.1 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.1 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.0 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 0.3 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.1 GO:0004645 phosphorylase activity(GO:0004645)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 24.9 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 2.9 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 1.8 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 1.3 PID ARF 3PATHWAY Arf1 pathway
0.0 0.8 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 1.3 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.4 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.9 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 1.0 PID RHOA PATHWAY RhoA signaling pathway
0.0 1.1 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.7 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 1.1 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.2 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.4 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 25.1 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.1 1.8 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 1.2 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.1 2.6 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 1.1 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 1.8 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1 0.3 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.1 1.2 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 2.8 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.6 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 1.2 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 1.0 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.4 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS Genes involved in CREB phosphorylation through the activation of Ras
0.0 0.9 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.4 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 1.6 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.4 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.4 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.5 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 1.2 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.4 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.6 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.4 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 1.0 REACTOME RNA POL I RNA POL III AND MITOCHONDRIAL TRANSCRIPTION Genes involved in RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
0.0 0.7 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.3 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.3 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 0.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.5 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 0.3 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.0 0.4 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.3 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation