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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for RORA

Z-value: 0.75

Motif logo

Transcription factors associated with RORA

Gene Symbol Gene ID Gene Info
ENSG00000069667.16 RORA

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RORAhg38_v1_chr15_-_61229297_612293060.573.2e-03Click!

Activity profile of RORA motif

Sorted Z-values of RORA motif

Network of associatons between targets according to the STRING database.

First level regulatory network of RORA

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr12_+_93569814 2.95 ENST00000340600.6
suppressor of cytokine signaling 2
chr12_+_93570381 2.83 ENST00000549206.5
suppressor of cytokine signaling 2
chr3_+_46407251 1.81 ENST00000399036.4
C-C motif chemokine receptor like 2
chr3_+_46407558 1.76 ENST00000357392.4
ENST00000400880.3
ENST00000433848.1
C-C motif chemokine receptor like 2
chr3_+_141386393 1.59 ENST00000503809.5
zinc finger and BTB domain containing 38
chr4_-_185810894 1.46 ENST00000448662.6
ENST00000439049.5
ENST00000420158.5
ENST00000319471.13
sorbin and SH3 domain containing 2
chr3_-_18438767 1.03 ENST00000454909.6
SATB homeobox 1
chr14_+_103121457 0.99 ENST00000333007.8
TNF alpha induced protein 2
chr19_-_15125095 0.97 ENST00000600984.5
ilvB acetolactate synthase like
chr2_+_161160299 0.94 ENST00000440506.5
ENST00000429217.5
ENST00000406287.5
ENST00000402568.5
TRAF family member associated NFKB activator
chrX_+_10156960 0.77 ENST00000380833.9
chloride voltage-gated channel 4
chr5_+_40679907 0.73 ENST00000302472.4
prostaglandin E receptor 4
chr10_-_63269057 0.69 ENST00000542921.5
jumonji domain containing 1C
chr8_+_119208322 0.65 ENST00000614891.5
mal, T cell differentiation protein 2
chr5_-_88785493 0.65 ENST00000503554.4
myocyte enhancer factor 2C
chrX_-_130165699 0.64 ENST00000676328.1
ENST00000675857.1
ENST00000675427.1
ENST00000675092.1
apoptosis inducing factor mitochondria associated 1
chr1_+_212565334 0.63 ENST00000366981.8
ENST00000366987.6
activating transcription factor 3
chr9_+_128552558 0.61 ENST00000372731.8
ENST00000630804.2
ENST00000372739.7
ENST00000627441.2
ENST00000358161.9
ENST00000636257.1
spectrin alpha, non-erythrocytic 1
chr2_+_161160420 0.57 ENST00000392749.7
ENST00000405852.5
TRAF family member associated NFKB activator
chr11_+_65111845 0.56 ENST00000526809.5
ENST00000524986.5
ENST00000534371.5
ENST00000279263.14
ENST00000525385.5
ENST00000345348.9
ENST00000531321.5
ENST00000529414.5
ENST00000526085.5
ENST00000530750.5
transmembrane 7 superfamily member 2
chrX_-_130165664 0.56 ENST00000535724.6
ENST00000346424.6
ENST00000676436.1
apoptosis inducing factor mitochondria associated 1
chr2_+_108621260 0.55 ENST00000409441.5
LIM zinc finger domain containing 1
chr19_-_39335999 0.53 ENST00000602185.5
ENST00000598034.5
ENST00000601387.5
ENST00000595636.1
ENST00000253054.12
ENST00000594700.5
ENST00000597595.6
glia maturation factor gamma
chr3_-_184017863 0.50 ENST00000427120.6
ENST00000334444.11
ENST00000392579.6
ENST00000382494.6
ENST00000265586.10
ENST00000446941.2
ATP binding cassette subfamily C member 5
chr1_+_52142044 0.45 ENST00000287727.8
ENST00000371591.2
zinc finger FYVE-type containing 9
chr5_+_73813518 0.45 ENST00000296799.8
Rho guanine nucleotide exchange factor 28
chr16_-_49664225 0.44 ENST00000535559.5
zinc finger protein 423
chr16_+_82056423 0.40 ENST00000568090.5
hydroxysteroid 17-beta dehydrogenase 2
chr1_+_28887166 0.38 ENST00000347529.7
erythrocyte membrane protein band 4.1
chr7_+_128758947 0.38 ENST00000493278.1
calumenin
chrX_-_130165825 0.36 ENST00000675240.1
ENST00000319908.8
ENST00000674546.1
ENST00000287295.8
apoptosis inducing factor mitochondria associated 1
chr6_-_106629472 0.35 ENST00000369063.8
reticulon 4 interacting protein 1
chr2_+_10420021 0.34 ENST00000422133.1
hippocalcin like 1
chr13_-_113864062 0.34 ENST00000327773.7
growth arrest specific 6
chr3_-_142029108 0.34 ENST00000497579.5
transcription factor Dp-2
chr2_-_208254232 0.34 ENST00000415913.5
ENST00000415282.5
ENST00000446179.5
isocitrate dehydrogenase (NADP(+)) 1
chrX_-_150898592 0.33 ENST00000355149.8
ENST00000466436.5
ENST00000370377.8
CD99 molecule like 2
chr12_-_6606642 0.32 ENST00000545584.2
ENST00000545942.6
chromodomain helicase DNA binding protein 4
chr19_+_46347063 0.32 ENST00000012443.9
ENST00000391919.1
protein phosphatase 5 catalytic subunit
chr6_+_36871841 0.31 ENST00000359359.6
chromosome 6 open reading frame 89
chr10_-_101818425 0.31 ENST00000361464.8
ENST00000439817.5
O-GlcNAcase
chr12_-_120265719 0.31 ENST00000637617.2
ENST00000267257.11
ENST00000228307.11
ENST00000424649.6
paxillin
chrX_-_150898779 0.31 ENST00000613030.4
ENST00000437787.6
CD99 molecule like 2
chr6_+_42929127 0.30 ENST00000394142.7
canopy FGF signaling regulator 3
chr3_+_52779916 0.30 ENST00000537050.5
inter-alpha-trypsin inhibitor heavy chain 1
chr19_+_49043837 0.29 ENST00000301408.7
chorionic gonadotropin subunit beta 5
chr17_-_64390852 0.28 ENST00000563924.6
platelet and endothelial cell adhesion molecule 1
chr16_+_28292485 0.28 ENST00000341901.5
SH3 domain binding kinase 1
chr5_+_38258373 0.27 ENST00000354891.7
EGF like, fibronectin type III and laminin G domains
chr5_-_137736066 0.27 ENST00000309755.9
kelch like family member 3
chr17_+_2796404 0.26 ENST00000366401.8
ENST00000254695.13
ENST00000542807.1
RAP1 GTPase activating protein 2
chr3_-_113746059 0.26 ENST00000477813.5
N-alpha-acetyltransferase 50, NatE catalytic subunit
chr12_+_10213417 0.26 ENST00000546017.5
ENST00000535576.5
ENST00000539170.5
GABA type A receptor associated protein like 1
chr22_-_23767876 0.26 ENST00000520222.1
ENST00000401675.7
ENST00000484558.3
coiled-coil-helix-coiled-coil-helix domain containing 10
chr18_-_58629084 0.26 ENST00000361673.4
alpha kinase 2
chr5_-_137735997 0.25 ENST00000505853.1
kelch like family member 3
chr16_+_31355165 0.25 ENST00000562918.5
ENST00000268296.9
integrin subunit alpha X
chr17_-_29176752 0.24 ENST00000533112.5
myosin XVIIIA
chr12_+_18242955 0.24 ENST00000676171.1
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma
chr16_-_47143934 0.24 ENST00000562435.6
neuropilin and tolloid like 2
chr11_-_7963646 0.24 ENST00000328600.3
NLR family pyrin domain containing 10
chr5_+_38258551 0.24 ENST00000322350.10
EGF like, fibronectin type III and laminin G domains
chr19_-_49808639 0.24 ENST00000529634.2
fuzzy planar cell polarity protein
chr5_+_170861990 0.23 ENST00000523189.6
RAN binding protein 17
chr20_+_59577463 0.23 ENST00000359926.7
phosphatase and actin regulator 3
chr6_+_54083423 0.23 ENST00000460844.6
ENST00000370876.6
muscular LMNA interacting protein
chr5_+_140647802 0.23 ENST00000417647.7
ENST00000507593.5
ENST00000508301.5
IK cytokine
chr19_+_54102838 0.23 ENST00000391762.5
ENST00000471292.5
ENST00000485876.6
ENST00000391763.3
ENST00000391764.7
ENST00000303553.5
NADH:ubiquinone oxidoreductase subunit A3
chr7_+_129368123 0.22 ENST00000460109.5
ENST00000474594.5
adenosylhomocysteinase like 2
chr7_-_128775793 0.22 ENST00000249389.3
opsin 1, short wave sensitive
chr19_+_34994778 0.22 ENST00000599564.5
GRAM domain containing 1A
chr20_+_34977625 0.21 ENST00000618182.6
myosin heavy chain 7B
chr9_-_39239174 0.21 ENST00000358144.6
contactin associated protein family member 3
chr14_-_58427134 0.21 ENST00000555930.6
translocase of inner mitochondrial membrane 9
chr6_+_44158807 0.21 ENST00000532171.5
ENST00000398776.2
calpain 11
chr16_+_31355215 0.21 ENST00000562522.2
integrin subunit alpha X
chr17_+_44070857 0.20 ENST00000591696.1
glucose-6-phosphatase catalytic subunit 3
chr3_+_45026296 0.20 ENST00000296130.5
C-type lectin domain family 3 member B
chr21_+_46001300 0.19 ENST00000612273.2
ENST00000682634.1
collagen type VI alpha 1 chain
chr6_-_88963409 0.19 ENST00000369475.7
ENST00000538899.2
RNA guanylyltransferase and 5'-phosphatase
chr1_-_91021996 0.19 ENST00000337393.10
zinc finger protein 644
chr19_+_8413270 0.19 ENST00000381035.8
ENST00000595142.5
ENST00000601724.5
ENST00000601283.5
ENST00000215555.7
ENST00000595213.1
membrane associated ring-CH-type finger 2
chr3_-_50322733 0.18 ENST00000428028.1
ENST00000357750.9
hyaluronidase 2
chr19_+_15949008 0.18 ENST00000322107.1
olfactory receptor family 10 subfamily H member 4
chr19_-_11578937 0.18 ENST00000592659.1
ENST00000592828.6
ENST00000218758.9
ENST00000412435.6
acid phosphatase 5, tartrate resistant
chr3_-_50322759 0.18 ENST00000442581.1
ENST00000447092.5
hyaluronidase 2
chr3_-_27456743 0.18 ENST00000295736.9
ENST00000428386.5
ENST00000428179.1
solute carrier family 4 member 7
chrX_-_72307148 0.18 ENST00000453707.6
ENST00000373619.7
Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1
chr1_+_161202147 0.18 ENST00000392179.5
ENST00000678511.1
ENST00000677453.1
ENST00000678783.1
ENST00000679218.1
ENST00000676972.1
NADH:ubiquinone oxidoreductase core subunit S2
chr16_+_2026834 0.17 ENST00000424542.7
ENST00000432365.6
SLC9A3 regulator 2
chr10_-_101818405 0.17 ENST00000357797.9
ENST00000370094.7
O-GlcNAcase
chr12_-_57742120 0.16 ENST00000257897.7
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr6_-_52244500 0.16 ENST00000336123.5
interleukin 17F
chr6_-_41071825 0.16 ENST00000468811.5
O-acyl-ADP-ribose deacylase 1
chr4_-_6070162 0.16 ENST00000636216.1
ENST00000637373.2
novel protein
janus kinase and microtubule interacting protein 1
chr17_-_2025289 0.15 ENST00000331238.7
reticulon 4 receptor like 1
chr5_+_141338753 0.15 ENST00000528330.2
ENST00000394576.3
protocadherin gamma subfamily A, 2
chr20_+_3796288 0.15 ENST00000439880.6
ENST00000245960.10
cell division cycle 25B
chr18_-_46098275 0.15 ENST00000589252.5
ENST00000398752.11
ENST00000590665.5
ENST00000593152.6
ATP synthase F1 subunit alpha
chr3_-_9986682 0.14 ENST00000429759.5
ER membrane protein complex subunit 3
chr3_+_113747022 0.14 ENST00000273398.8
ENST00000496747.5
ENST00000475322.1
ATPase H+ transporting V1 subunit A
chr1_+_46175079 0.14 ENST00000372003.6
tetraspanin 1
chr16_-_1782526 0.14 ENST00000566339.6
splA/ryanodine receptor domain and SOCS box containing 3
chr20_+_50510321 0.13 ENST00000541713.5
ENST00000371621.5
protein tyrosine phosphatase non-receptor type 1
chr8_+_37695774 0.13 ENST00000331569.6
zinc finger protein 703
chr1_-_33036927 0.13 ENST00000354858.11
adenylate kinase 2
chr19_-_50837213 0.13 ENST00000326856.8
kallikrein related peptidase 15
chr16_+_21953341 0.13 ENST00000268379.9
ENST00000561553.5
ENST00000565331.5
ubiquinol-cytochrome c reductase core protein 2
chr11_+_112086853 0.12 ENST00000528182.5
ENST00000528048.5
ENST00000375549.8
ENST00000528021.6
ENST00000526592.5
ENST00000525291.5
succinate dehydrogenase complex subunit D
chr8_-_99893622 0.12 ENST00000520271.5
ENST00000522940.5
ENST00000523016.1
ENST00000517682.6
ENST00000297564.6
cytochrome c oxidase subunit 6C
chr8_-_99893697 0.12 ENST00000518171.5
ENST00000520468.7
cytochrome c oxidase subunit 6C
chr11_-_33717409 0.12 ENST00000651485.1
CD59 molecule (CD59 blood group)
chr2_+_37925256 0.12 ENST00000354545.8
regulator of microtubule dynamics 2
chr1_+_32765667 0.12 ENST00000373480.1
KIAA1522
chr7_+_112423137 0.11 ENST00000005558.8
ENST00000621379.4
interferon related developmental regulator 1
chr5_-_134367144 0.11 ENST00000265334.9
cyclin dependent kinase like 3
chr2_+_148021083 0.11 ENST00000642680.2
methyl-CpG binding domain protein 5
chr7_-_123557679 0.11 ENST00000677264.1
ENST00000471770.5
ENST00000676730.1
ENST00000677391.1
ENST00000677251.1
ENST00000470123.2
ENST00000679163.1
ENST00000676614.1
ENST00000378795.9
ENST00000676516.1
ENST00000355749.7
ENST00000678090.1
NADH:ubiquinone oxidoreductase subunit A5
chr12_-_52926459 0.10 ENST00000552150.5
keratin 8
chr12_+_120438107 0.10 ENST00000229379.3
ENST00000551806.1
cytochrome c oxidase subunit 6A1
novel protein
chr2_+_206159884 0.10 ENST00000392222.7
eukaryotic translation elongation factor 1 beta 2
chr19_-_15125659 0.10 ENST00000533747.1
ENST00000598709.1
ENST00000534378.5
ilvB acetolactate synthase like
chr5_-_140647590 0.08 ENST00000252102.9
ENST00000512088.1
NADH:ubiquinone oxidoreductase subunit A2
chr2_+_197500398 0.08 ENST00000604458.1
HSPE1-MOB4 readthrough
chr10_+_73998104 0.08 ENST00000372755.7
ENST00000211998.10
vinculin
chr3_+_179604785 0.08 ENST00000611971.4
ENST00000493866.5
ENST00000259037.8
ENST00000472629.5
ENST00000482604.5
NADH:ubiquinone oxidoreductase subunit B5
chr12_+_71686473 0.08 ENST00000549735.5
transmembrane protein 19
chr16_+_727117 0.08 ENST00000562141.5
hydroxyacylglutathione hydrolase like
chr6_-_88963573 0.08 ENST00000369485.9
RNA guanylyltransferase and 5'-phosphatase
chr11_-_6440980 0.07 ENST00000265983.8
ENST00000615166.1
hemopexin
chr11_-_111871271 0.07 ENST00000398006.6
ALG9 alpha-1,2-mannosyltransferase
chr19_+_35030438 0.07 ENST00000415950.5
ENST00000262631.11
sodium voltage-gated channel beta subunit 1
chr1_+_165631199 0.07 ENST00000367888.8
ENST00000367889.8
ENST00000367885.5
ENST00000367884.6
microsomal glutathione S-transferase 3
chr2_+_206159580 0.07 ENST00000236957.9
ENST00000392221.5
ENST00000445505.5
eukaryotic translation elongation factor 1 beta 2
chr2_-_197499857 0.07 ENST00000428204.6
ENST00000678170.1
ENST00000676933.1
ENST00000678621.1
heat shock protein family D (Hsp60) member 1
chr8_-_99893135 0.06 ENST00000524245.5
cytochrome c oxidase subunit 6C
chr1_-_33036840 0.06 ENST00000548033.5
ENST00000487289.1
ENST00000626911.1
ENST00000673291.1
ENST00000480134.5
ENST00000373449.7
ENST00000672715.1
ENST00000467905.5
ENST00000629371.2
adenylate kinase 2
chr9_-_35685462 0.06 ENST00000607559.1
tropomyosin 2
chr7_-_151080787 0.06 ENST00000540185.5
ENST00000297532.11
Fas activated serine/threonine kinase
chr2_-_197499826 0.06 ENST00000439605.2
ENST00000388968.8
ENST00000418022.2
heat shock protein family D (Hsp60) member 1
chr1_-_168137430 0.06 ENST00000546300.5
ENST00000271357.9
ENST00000367835.1
ENST00000537209.5
G protein-coupled receptor 161
chr6_+_30626842 0.06 ENST00000318999.11
ENST00000376485.8
ENST00000330083.6
ENST00000319027.9
ENST00000376483.8
ENST00000329992.12
alpha tubulin acetyltransferase 1
chr11_-_112086727 0.05 ENST00000504148.3
ENST00000541231.1
translocase of inner mitochondrial membrane 8 homolog B
chr16_+_727246 0.05 ENST00000561546.5
ENST00000564545.1
ENST00000567414.5
ENST00000568141.5
hydroxyacylglutathione hydrolase like
chr6_-_70303070 0.05 ENST00000370496.3
ENST00000357250.11
collagen type IX alpha 1 chain
chr9_+_131228109 0.05 ENST00000498010.2
ENST00000476004.5
ENST00000528406.1
nucleoporin 214
chr2_+_197500371 0.04 ENST00000409468.1
ENST00000233893.10
heat shock protein family E (Hsp10) member 1
chrX_+_80335504 0.04 ENST00000538312.5
terminal nucleotidyltransferase 5D
chr7_-_151080833 0.04 ENST00000353841.6
ENST00000482571.2
Fas activated serine/threonine kinase
chr17_+_76079182 0.04 ENST00000334586.10
zinc activated ion channel
chr19_-_5622768 0.04 ENST00000252542.9
scaffold attachment factor B2
chr7_+_123601836 0.03 ENST00000434204.5
ankyrin repeat and SOCS box containing 15
chr16_-_30029429 0.03 ENST00000564806.1
TLC domain containing 3B
chr19_-_15125751 0.03 ENST00000263383.8
ilvB acetolactate synthase like
chr7_+_123601815 0.03 ENST00000451215.6
ankyrin repeat and SOCS box containing 15
chr4_+_37244735 0.03 ENST00000309447.6
NACHT and WD repeat domain containing 2
chr2_-_86194972 0.02 ENST00000254636.9
inner membrane mitochondrial protein
chr19_-_54313074 0.02 ENST00000486742.2
ENST00000432233.8
leukocyte immunoglobulin like receptor A5
chr2_+_70087468 0.02 ENST00000303577.7
poly(rC) binding protein 1
chr3_-_113746185 0.02 ENST00000616174.1
N-alpha-acetyltransferase 50, NatE catalytic subunit
chr20_-_13990609 0.02 ENST00000284951.10
ENST00000378072.5
SEL1L2 adaptor subunit of ERAD E3 ligase
chr16_+_56865202 0.02 ENST00000566786.5
ENST00000438926.6
ENST00000563236.6
ENST00000262502.5
solute carrier family 12 member 3
chr2_-_206159509 0.02 ENST00000423725.5
NADH:ubiquinone oxidoreductase core subunit S1
chrX_-_30309387 0.02 ENST00000378970.5
nuclear receptor subfamily 0 group B member 1
chr12_+_65279445 0.02 ENST00000642404.1
methionine sulfoxide reductase B3
chr9_-_83707889 0.02 ENST00000257468.11
ENST00000376395.9
ubiquilin 1
chr19_-_39435627 0.01 ENST00000599705.1
ribosomal protein S16
chr12_-_6375209 0.01 ENST00000360168.7
sodium channel epithelial 1 subunit alpha
chr11_-_64744102 0.01 ENST00000431822.5
ENST00000394432.8
ENST00000377486.7
RAS guanyl releasing protein 2
chr18_-_21704763 0.01 ENST00000580981.5
ENST00000289119.7
abhydrolase domain containing 3, phospholipase
chr6_+_39048765 0.01 ENST00000373256.5
glucagon like peptide 1 receptor
chr1_-_205750167 0.01 ENST00000367142.5
nuclear casein kinase and cyclin dependent kinase substrate 1
chr1_-_153550083 0.01 ENST00000368714.1
S100 calcium binding protein A4
chr15_-_74725370 0.00 ENST00000567032.5
ENST00000564596.5
ENST00000566503.1
ENST00000395049.8
ENST00000379727.8
ENST00000617691.4
ENST00000395048.6
cytochrome P450 family 1 subfamily A member 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.6 GO:1904045 cellular response to aldosterone(GO:1904045)
0.3 5.8 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.3 1.5 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.2 0.7 GO:2000417 negative regulation of eosinophil migration(GO:2000417)
0.2 0.6 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.1 0.5 GO:0072156 distal tubule morphogenesis(GO:0072156)
0.1 0.3 GO:0097252 oligodendrocyte apoptotic process(GO:0097252)
0.1 0.3 GO:0006097 glyoxylate cycle(GO:0006097)
0.1 0.3 GO:0098507 polynucleotide 5' dephosphorylation(GO:0098507)
0.1 0.2 GO:1903028 positive regulation of opsonization(GO:1903028)
0.1 0.6 GO:0003138 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.1 0.4 GO:0070295 transformation of host cell by virus(GO:0019087) renal water absorption(GO:0070295)
0.1 0.3 GO:0072011 diapedesis(GO:0050904) glomerular endothelium development(GO:0072011)
0.1 0.5 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.1 0.3 GO:2000984 regulation of ATP citrate synthase activity(GO:2000983) negative regulation of ATP citrate synthase activity(GO:2000984)
0.1 1.0 GO:0051601 exocyst localization(GO:0051601)
0.1 1.0 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 0.2 GO:2000314 regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.1 0.7 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.2 GO:0006172 ADP biosynthetic process(GO:0006172)
0.0 0.2 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 0.1 GO:2000646 positive regulation of receptor catabolic process(GO:2000646)
0.0 0.1 GO:0045041 B cell cytokine production(GO:0002368) protein import into mitochondrial intermembrane space(GO:0045041)
0.0 0.1 GO:0007518 myoblast fate determination(GO:0007518)
0.0 1.5 GO:0061049 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.2 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.0 0.1 GO:0071962 mitotic sister chromatid cohesion, centromeric(GO:0071962)
0.0 0.7 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.2 GO:0042109 lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.0 0.2 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 3.5 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 0.5 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.0 0.1 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0 0.2 GO:0071105 response to interleukin-11(GO:0071105)
0.0 0.3 GO:0072553 terminal button organization(GO:0072553)
0.0 0.3 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.0 0.2 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.5 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.1 GO:0001971 negative regulation of activation of membrane attack complex(GO:0001971)
0.0 0.3 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.2 GO:2000318 positive regulation of T-helper 17 type immune response(GO:2000318)
0.0 0.3 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.4 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 0.2 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.0 0.1 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.0 0.1 GO:0021966 corticospinal neuron axon guidance(GO:0021966)
0.0 0.4 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.3 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.3 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.4 GO:0007184 SMAD protein import into nucleus(GO:0007184)
0.0 0.8 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.0 0.1 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.5 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894)
0.0 0.1 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0 0.2 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.6 GO:0051693 actin filament capping(GO:0051693)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.0 0.3 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.4 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 1.0 GO:0000145 exocyst(GO:0000145)
0.0 0.6 GO:0008091 spectrin(GO:0008091)
0.0 0.2 GO:0001652 granular component(GO:0001652)
0.0 0.1 GO:0005749 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 1.0 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.4 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.5 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.5 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 2.0 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.2 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.2 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.1 GO:0031415 NatA complex(GO:0031415)
0.0 0.2 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.1 GO:0097443 sorting endosome(GO:0097443)
0.0 0.0 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.0 0.1 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.1 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 5.8 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.3 1.5 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.2 0.6 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.1 0.4 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.1 1.6 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.1 0.3 GO:0051990 isocitrate dehydrogenase (NADP+) activity(GO:0004450) (R)-2-hydroxyglutarate dehydrogenase activity(GO:0051990)
0.1 1.1 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.1 0.3 GO:0004651 polynucleotide 5'-phosphatase activity(GO:0004651)
0.1 3.6 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.1 0.4 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.1 0.7 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.1 0.2 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0 1.5 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 1.5 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.7 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.5 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.2 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.1 GO:0052858 peptidyl-lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0052858)
0.0 0.7 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.6 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.1 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.0 0.1 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.8 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.5 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.8 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.2 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.1 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.0 0.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.2 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.4 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.1 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.0 0.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.2 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.2 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.4 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.3 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.3 GO:0017166 vinculin binding(GO:0017166)
0.0 0.2 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.2 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.3 GO:0001965 G-protein alpha-subunit binding(GO:0001965)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.8 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 1.6 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 1.6 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.4 PID IGF1 PATHWAY IGF1 pathway
0.0 0.6 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.1 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.4 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.9 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.1 0.7 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 1.5 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.9 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.3 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.3 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.3 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.6 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.2 REACTOME OPSINS Genes involved in Opsins
0.0 0.5 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.6 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 1.0 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.6 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.6 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 1.0 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport