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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for RREB1

Z-value: 0.62

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Transcription factors associated with RREB1

Gene Symbol Gene ID Gene Info
ENSG00000124782.20 RREB1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RREB1hg38_v1_chr6_+_7107597_7107821-0.452.6e-02Click!

Activity profile of RREB1 motif

Sorted Z-values of RREB1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of RREB1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr10_+_113679159 2.70 ENST00000621345.4
ENST00000429617.5
ENST00000369331.8
caspase 7
chr14_+_103121457 2.65 ENST00000333007.8
TNF alpha induced protein 2
chr4_+_73869385 1.93 ENST00000395761.4
C-X-C motif chemokine ligand 1
chr1_+_212608628 1.76 ENST00000613954.4
ENST00000341491.9
ENST00000366985.5
activating transcription factor 3
chr12_-_57129001 1.42 ENST00000556155.5
signal transducer and activator of transcription 6
chr21_+_36135071 1.41 ENST00000290354.6
carbonyl reductase 3
chr3_-_39153512 1.05 ENST00000273153.10
cysteine and serine rich nuclear protein 1
chr11_+_1099730 1.04 ENST00000674892.1
mucin 2, oligomeric mucus/gel-forming
chr4_+_8229170 0.92 ENST00000511002.6
SH3 domain and tetratricopeptide repeats 1
chr5_+_126423363 0.86 ENST00000285689.8
GRAM domain containing 2B
chr17_+_7023042 0.86 ENST00000293805.10
BCL6B transcription repressor
chr5_+_126423176 0.86 ENST00000542322.5
ENST00000544396.5
GRAM domain containing 2B
chr5_+_126423122 0.86 ENST00000515200.5
GRAM domain containing 2B
chr11_-_9265078 0.76 ENST00000530044.5
ENST00000679568.1
ENST00000680294.1
ENST00000681203.1
DENN domain containing 5A
chr11_-_9265302 0.73 ENST00000328194.8
DENN domain containing 5A
chr16_+_50693568 0.70 ENST00000647318.2
ENST00000531674.1
nucleotide binding oligomerization domain containing 2
chr11_-_59668981 0.67 ENST00000300146.10
PAT1 homolog 1, processing body mRNA decay factor
chr3_-_39154558 0.65 ENST00000514182.1
cysteine and serine rich nuclear protein 1
chr2_-_3558280 0.64 ENST00000315212.4
ribonuclease H1
chr16_+_27313879 0.60 ENST00000562142.5
ENST00000561742.5
ENST00000543915.6
ENST00000395762.7
ENST00000563002.5
interleukin 4 receptor
chr21_+_42653585 0.59 ENST00000291539.11
phosphodiesterase 9A
chr11_+_67119245 0.58 ENST00000529006.7
ENST00000398645.6
lysine demethylase 2A
chr21_+_42653734 0.57 ENST00000335512.8
ENST00000328862.10
ENST00000335440.10
ENST00000380328.6
ENST00000398225.7
ENST00000398227.7
ENST00000398229.7
ENST00000398232.7
ENST00000398234.7
ENST00000398236.7
ENST00000349112.7
ENST00000398224.3
phosphodiesterase 9A
chr17_-_60422404 0.56 ENST00000588898.1
ubiquitin specific peptidase 32
chrX_-_120115909 0.55 ENST00000217999.3
Rhox homeobox family member 1
chr20_-_45101112 0.54 ENST00000306117.5
ENST00000537075.3
potassium voltage-gated channel modifier subfamily S member 1
chr1_-_204411804 0.54 ENST00000367188.5
protein phosphatase 1 regulatory subunit 15B
chr3_+_41200080 0.54 ENST00000644524.1
catenin beta 1
chr11_-_57322197 0.51 ENST00000532437.1
tankyrase 1 binding protein 1
chr3_+_41200104 0.49 ENST00000643297.1
ENST00000450969.6
catenin beta 1
chr19_+_43581037 0.49 ENST00000562365.2
phospholipase A2 inhibitor and LY6/PLAUR domain containing
chr12_-_52680398 0.49 ENST00000252244.3
keratin 1
chr5_+_151771884 0.48 ENST00000627077.2
ENST00000678976.1
ENST00000677408.1
ENST00000678070.1
ENST00000678964.1
ENST00000678925.1
ENST00000394123.7
ENST00000522761.6
ENST00000676827.1
G3BP stress granule assembly factor 1
chr20_+_836052 0.47 ENST00000246100.3
family with sequence similarity 110 member A
chr5_+_151771943 0.45 ENST00000520177.6
ENST00000678854.1
ENST00000520006.2
ENST00000677105.1
ENST00000678101.1
ENST00000678910.1
ENST00000356245.8
ENST00000678646.1
ENST00000677433.1
ENST00000677369.1
ENST00000677284.1
ENST00000678564.1
G3BP stress granule assembly factor 1
chr12_+_26195647 0.45 ENST00000535504.1
sarcospan
chr19_-_43802438 0.45 ENST00000377950.8
LY6/PLAUR domain containing 5
chr7_-_51316754 0.44 ENST00000632460.1
ENST00000441453.5
ENST00000648294.1
ENST00000265136.12
ENST00000395542.6
ENST00000395540.6
cordon-bleu WH2 repeat protein
chr3_-_71583713 0.43 ENST00000649528.3
ENST00000471386.3
ENST00000493089.7
forkhead box P1
chr12_-_12562851 0.42 ENST00000298573.9
dual specificity phosphatase 16
chr20_+_59604527 0.42 ENST00000371015.6
phosphatase and actin regulator 3
chr13_+_24160705 0.41 ENST00000382108.8
spermatogenesis associated 13
chr14_+_104689588 0.40 ENST00000330634.11
ENST00000392634.9
ENST00000675482.1
ENST00000398337.8
inverted formin 2
chr16_+_1678304 0.40 ENST00000569765.5
Jupiter microtubule associated homolog 2
chr11_+_7485492 0.40 ENST00000534244.1
ENST00000329293.4
olfactomedin like 1
chr10_-_3785197 0.39 ENST00000497571.6
Kruppel like factor 6
chr10_-_3785179 0.37 ENST00000469435.1
Kruppel like factor 6
chr12_+_131929219 0.37 ENST00000322060.9
pseudouridine synthase 1
chr2_+_105851748 0.36 ENST00000425756.1
ENST00000393349.2
NCK adaptor protein 2
chr3_-_71583683 0.36 ENST00000649631.1
ENST00000648718.1
forkhead box P1
chr2_+_28395511 0.36 ENST00000436647.1
FOS like 2, AP-1 transcription factor subunit
chr10_-_3785225 0.36 ENST00000542957.1
Kruppel like factor 6
chr1_+_109548567 0.35 ENST00000369851.7
G protein subunit alpha i3
chr8_+_141416078 0.35 ENST00000349124.3
protein tyrosine phosphatase 4A3
chr8_+_141416141 0.35 ENST00000680615.1
protein tyrosine phosphatase 4A3
chr9_-_133348022 0.34 ENST00000446777.5
ENST00000610888.4
ENST00000371999.5
ENST00000494177.6
ENST00000343730.10
ENST00000457204.2
mediator complex subunit 22
chr17_-_33293247 0.33 ENST00000225823.7
acid sensing ion channel subunit 2
chr17_+_79778135 0.33 ENST00000310942.9
ENST00000269399.5
chromobox 2
chr11_-_75351686 0.33 ENST00000360025.7
arrestin beta 1
chr14_+_100019375 0.33 ENST00000544450.6
Enah/Vasp-like
chr19_+_43580544 0.33 ENST00000562255.5
ENST00000569031.6
phospholipase A2 inhibitor and LY6/PLAUR domain containing
chr16_+_397209 0.32 ENST00000382940.8
NME/NM23 nucleoside diphosphate kinase 4
chr15_+_75206398 0.32 ENST00000565074.1
chromosome 15 open reading frame 39
chr12_-_6607397 0.31 ENST00000645005.1
ENST00000646806.1
chromodomain helicase DNA binding protein 4
chr8_+_32548210 0.31 ENST00000523079.5
ENST00000650919.1
neuregulin 1
chr11_+_128693887 0.31 ENST00000281428.12
Fli-1 proto-oncogene, ETS transcription factor
chr8_+_32548303 0.30 ENST00000650967.1
neuregulin 1
chr7_-_92836555 0.30 ENST00000424848.3
cyclin dependent kinase 6
chr20_+_833781 0.30 ENST00000381939.1
family with sequence similarity 110 member A
chr8_-_133102477 0.30 ENST00000522119.5
ENST00000523610.5
ENST00000338087.10
ENST00000521302.5
ENST00000519558.5
ENST00000519747.5
ENST00000517648.5
Src like adaptor
chr18_+_57435366 0.30 ENST00000491143.3
one cut homeobox 2
chr9_-_21994345 0.29 ENST00000579755.2
ENST00000530628.2
cyclin dependent kinase inhibitor 2A
chr8_+_89902529 0.29 ENST00000451899.7
oxidative stress induced growth inhibitor family member 2
chr3_+_41199462 0.29 ENST00000647264.1
ENST00000645900.1
ENST00000646174.1
ENST00000643992.1
ENST00000647390.1
ENST00000642886.1
catenin beta 1
chr12_-_6607334 0.28 ENST00000645645.1
ENST00000357008.7
ENST00000544484.6
ENST00000544040.7
chromodomain helicase DNA binding protein 4
chr8_-_133102874 0.27 ENST00000395352.7
Src like adaptor
chr1_+_101238090 0.27 ENST00000475289.2
sphingosine-1-phosphate receptor 1
chr12_-_121793668 0.27 ENST00000267205.7
ras homolog family member F, filopodia associated
chr11_-_64935882 0.26 ENST00000532246.1
ENST00000279168.7
glycoprotein hormone subunit alpha 2
chr10_-_73655984 0.26 ENST00000394810.3
synaptopodin 2 like
chr19_-_15331890 0.26 ENST00000594841.5
ENST00000601941.1
bromodomain containing 4
chr9_+_129665603 0.26 ENST00000372469.6
paired related homeobox 2
chr16_+_1678271 0.25 ENST00000562684.5
ENST00000561516.5
ENST00000248098.8
ENST00000382711.9
ENST00000566742.5
Jupiter microtubule associated homolog 2
chr9_-_114682172 0.25 ENST00000436752.3
testis expressed 48
chr15_-_77632869 0.25 ENST00000355300.7
leucine rich repeat and Ig domain containing 1
chr1_-_1779976 0.25 ENST00000378625.5
NAD kinase
chr8_+_32548267 0.25 ENST00000356819.7
neuregulin 1
chr9_+_130172343 0.25 ENST00000372398.6
neuronal calcium sensor 1
chr17_-_60422337 0.25 ENST00000590297.1
ubiquitin specific peptidase 32
chr11_-_61429715 0.23 ENST00000449811.5
ENST00000413232.5
ENST00000340437.8
ENST00000539952.5
ENST00000544585.5
ENST00000450000.5
cleavage and polyadenylation specific factor 7
chr16_+_397226 0.23 ENST00000433358.5
NME/NM23 nucleoside diphosphate kinase 4
chr15_+_76336755 0.23 ENST00000290759.9
ISL LIM homeobox 2
chr1_-_155978144 0.23 ENST00000313695.11
ENST00000497907.5
Rho/Rac guanine nucleotide exchange factor 2
chrY_-_2500895 0.23 ENST00000461691.6_PAR_Y
ENST00000381222.8_PAR_Y
ENST00000381223.9_PAR_Y
ENST00000652001.1_PAR_Y
ENST00000412516.7_PAR_Y
ENST00000334651.11_PAR_Y
zinc finger BED-type containing 1
dehydrogenase/reductase X-linked
chrX_-_2500895 0.22 ENST00000461691.6
ENST00000381222.8
ENST00000381223.9
ENST00000652001.1
ENST00000412516.7
ENST00000334651.11
zinc finger BED-type containing 1
dehydrogenase/reductase X-linked
chr11_-_61429934 0.22 ENST00000541963.5
ENST00000477890.6
ENST00000439958.8
cleavage and polyadenylation specific factor 7
chr19_+_43576800 0.22 ENST00000612042.4
phospholipase A2 inhibitor and LY6/PLAUR domain containing
chr6_-_136526654 0.22 ENST00000611373.1
microtubule associated protein 7
chr18_+_13824149 0.22 ENST00000589410.2
melanocortin 5 receptor
chr19_-_47471886 0.22 ENST00000236877.11
ENST00000597014.1
solute carrier family 8 member A2
chrX_+_135032346 0.22 ENST00000257013.9
retrotransposon Gag like 8C
chr5_-_142686079 0.21 ENST00000337706.7
fibroblast growth factor 1
chr19_+_48364361 0.21 ENST00000344846.7
synaptogyrin 4
chr20_+_43667105 0.21 ENST00000217026.5
MYB proto-oncogene like 2
chr20_+_43667019 0.21 ENST00000396863.8
MYB proto-oncogene like 2
chr1_+_213987929 0.21 ENST00000498508.6
ENST00000366958.9
prospero homeobox 1
chr16_+_28878480 0.20 ENST00000395503.9
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
chr19_-_40714641 0.20 ENST00000678467.1
coenzyme Q8B
chr18_-_3874270 0.20 ENST00000400149.7
ENST00000400155.5
ENST00000400150.7
DLG associated protein 1
chr6_-_136526472 0.20 ENST00000454590.5
ENST00000432797.6
microtubule associated protein 7
chrX_+_123859976 0.20 ENST00000371199.8
X-linked inhibitor of apoptosis
chr12_-_49110840 0.20 ENST00000550137.5
ENST00000267102.13
ENST00000547382.5
limb development membrane protein 1 like
chr15_-_89221558 0.19 ENST00000268125.10
retinaldehyde binding protein 1
chr16_+_30407572 0.19 ENST00000319296.10
ENST00000566625.2
zinc finger protein 771
chr11_-_61430008 0.19 ENST00000394888.8
cleavage and polyadenylation specific factor 7
chrX_+_154585120 0.19 ENST00000593606.3
ENST00000599837.3
cancer/testis antigen 1A
chr12_-_12562344 0.19 ENST00000228862.3
dual specificity phosphatase 16
chrX_+_123859807 0.19 ENST00000434753.7
ENST00000430625.1
X-linked inhibitor of apoptosis
chr11_+_72080595 0.19 ENST00000647530.1
ENST00000539271.6
ENST00000642510.1
leucine rich transmembrane and O-methyltransferase domain containing
chr2_-_144520106 0.19 ENST00000627532.3
ENST00000539609.7
zinc finger E-box binding homeobox 2
chr16_-_1225257 0.18 ENST00000234798.4
tryptase gamma 1
chr10_-_99235846 0.18 ENST00000370552.8
ENST00000370549.5
ENST00000628193.2
heparanase 2 (inactive)
chr4_-_95548956 0.18 ENST00000513796.5
ENST00000453304.6
unc-5 netrin receptor C
chr12_-_57251169 0.18 ENST00000554578.5
ENST00000546246.2
ENST00000332782.7
ENST00000553489.1
SH3 and cysteine rich domain 3
chr9_-_104928139 0.17 ENST00000423487.6
ENST00000374733.1
ENST00000374736.8
ENST00000678995.1
ATP binding cassette subfamily A member 1
chr18_+_74499939 0.17 ENST00000584768.5
carnosine dipeptidase 2
chr16_+_30075967 0.17 ENST00000279387.12
ENST00000562664.5
ENST00000627746.2
ENST00000562222.5
protein phosphatase 4 catalytic subunit
chrX_-_40177213 0.17 ENST00000672922.2
ENST00000378455.8
ENST00000342274.8
BCL6 corepressor
chrX_-_154619282 0.17 ENST00000328435.3
ENST00000359887.4
cancer/testis antigen 1B
chr12_+_62260374 0.17 ENST00000312635.10
ENST00000280377.10
ENST00000549237.5
ubiquitin specific peptidase 15
chr2_-_37324826 0.17 ENST00000234179.8
protein kinase D3
chr8_+_32548590 0.17 ENST00000652588.1
ENST00000521670.5
ENST00000287842.7
neuregulin 1
chr6_+_33420201 0.17 ENST00000644458.1
ENST00000449372.7
ENST00000628646.2
ENST00000418600.7
synaptic Ras GTPase activating protein 1
chr17_+_29390326 0.17 ENST00000261716.8
TAO kinase 1
chr17_-_44066595 0.17 ENST00000585388.2
ENST00000293406.8
LSM12 homolog
chrX_-_50470818 0.16 ENST00000611977.2
diacylglycerol kinase kappa
chr5_-_179800540 0.16 ENST00000520875.5
alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B
chr16_+_67164730 0.16 ENST00000521374.6
heat shock transcription factor 4
chr8_-_113377125 0.16 ENST00000343508.7
CUB and Sushi multiple domains 3
chr8_+_32548661 0.16 ENST00000650980.1
ENST00000405005.7
neuregulin 1
chr19_+_55283982 0.16 ENST00000309383.6
BR serine/threonine kinase 1
chr18_-_23662810 0.16 ENST00000322980.13
ankyrin repeat domain 29
chr16_+_67164780 0.16 ENST00000517685.5
ENST00000584272.5
heat shock transcription factor 4
chr5_-_142685654 0.16 ENST00000378046.5
ENST00000619447.4
fibroblast growth factor 1
chr18_-_3874751 0.16 ENST00000515196.6
ENST00000534970.5
DLG associated protein 1
chr16_+_397183 0.16 ENST00000620944.4
ENST00000621774.4
ENST00000219479.7
NME/NM23 nucleoside diphosphate kinase 4
chr21_-_46228751 0.15 ENST00000450351.1
ENST00000397728.8
ENST00000522411.5
ENST00000356396.8
ENST00000457828.6
lanosterol synthase
chr10_-_99235783 0.15 ENST00000370546.5
ENST00000614306.1
heparanase 2 (inactive)
chr2_-_201643448 0.15 ENST00000409883.7
transmembrane protein 237
chr2_-_219243577 0.15 ENST00000409640.5
galactosidase beta 1 like
chr2_-_162838728 0.15 ENST00000328032.8
ENST00000332142.10
potassium voltage-gated channel subfamily H member 7
chrX_+_47223009 0.15 ENST00000518022.5
ENST00000276052.10
cyclin dependent kinase 16
chr19_-_15449920 0.15 ENST00000263381.12
ENST00000643092.1
ENST00000673675.1
WIZ zinc finger
chr19_-_29715060 0.15 ENST00000623113.2
chromosome 19 open reading frame 12
chr7_+_98211431 0.15 ENST00000609256.2
basic helix-loop-helix family member a15
chr19_-_29715221 0.14 ENST00000392276.1
ENST00000592153.5
ENST00000323670.14
chromosome 19 open reading frame 12
chr19_-_8610674 0.14 ENST00000597188.6
ADAM metallopeptidase with thrombospondin type 1 motif 10
chr3_+_8733779 0.14 ENST00000343849.3
ENST00000397368.2
caveolin 3
chr12_-_56258327 0.14 ENST00000267116.8
ankyrin repeat domain 52
chr3_-_116444983 0.14 ENST00000333617.8
limbic system associated membrane protein
chr2_-_127675065 0.14 ENST00000545738.6
ENST00000409808.6
LIM zinc finger domain containing 2
chr19_-_50952942 0.14 ENST00000594846.1
ENST00000336334.8
kallikrein related peptidase 5
chr18_+_74499861 0.14 ENST00000324301.12
carnosine dipeptidase 2
chr17_-_62065248 0.14 ENST00000397786.7
mediator complex subunit 13
chr19_-_47471847 0.14 ENST00000594353.1
ENST00000542837.2
solute carrier family 8 member A2
chr16_+_30957960 0.14 ENST00000684162.1
SET domain containing 1A, histone lysine methyltransferase
chr16_+_28878382 0.14 ENST00000357084.7
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
chr18_-_3874247 0.14 ENST00000581699.5
DLG associated protein 1
chr17_+_7015035 0.13 ENST00000552775.1
chromosome 17 open reading frame 49
chr16_-_21159441 0.13 ENST00000261383.3
dynein axonemal heavy chain 3
chr12_+_54053815 0.13 ENST00000430889.3
homeobox C4
chr5_-_151924824 0.13 ENST00000455880.2
glycine receptor alpha 1
chr2_-_127675459 0.13 ENST00000355119.9
LIM zinc finger domain containing 2
chr12_+_131929259 0.13 ENST00000542167.2
ENST00000376649.8
ENST00000538037.5
ENST00000456665.6
pseudouridine synthase 1
chr16_+_30957714 0.12 ENST00000262519.14
ENST00000682768.1
SET domain containing 1A, histone lysine methyltransferase
chr18_-_23662868 0.12 ENST00000586087.1
ENST00000592179.6
ankyrin repeat domain 29
chr17_-_4263847 0.12 ENST00000570535.5
ENST00000574367.5
ENST00000341657.9
ankyrin repeat and FYVE domain containing 1
chr12_+_66755 0.12 ENST00000538872.6
IQ motif and Sec7 domain ArfGEF 3
chr9_+_128411715 0.12 ENST00000420034.5
ENST00000372842.5
cerebral endothelial cell adhesion molecule
chr11_-_75351609 0.12 ENST00000420843.7
arrestin beta 1
chr19_-_50833187 0.12 ENST00000598673.1
kallikrein related peptidase 15
chr1_+_18631006 0.12 ENST00000375375.7
paired box 7
chr5_+_76850001 0.12 ENST00000513010.5
ENST00000317593.9
S100 calcium binding protein Z
chr13_-_108215498 0.11 ENST00000614526.1
ENST00000611712.4
ENST00000442234.6
DNA ligase 4
chr4_+_146638890 0.11 ENST00000281321.3
POU class 4 homeobox 2
chr19_+_2163915 0.11 ENST00000398665.8
DOT1 like histone lysine methyltransferase
chr22_+_32354885 0.11 ENST00000397468.5
ret finger protein like 3
chrX_+_151912878 0.11 ENST00000276344.6
MAGE family member A4
chr2_-_136116165 0.11 ENST00000409817.1
C-X-C motif chemokine receptor 4
chr22_-_35961623 0.11 ENST00000408983.2
RNA binding fox-1 homolog 2
chr17_+_7884783 0.11 ENST00000380358.9
chromodomain helicase DNA binding protein 3
chr14_+_23555983 0.11 ENST00000404535.3
thiamine triphosphatase
chr12_+_131929194 0.11 ENST00000443358.6
pseudouridine synthase 1
chrX_-_8801337 0.11 ENST00000543214.1
ENST00000381003.7
family with sequence similarity 9 member A
chr8_+_144477975 0.11 ENST00000435887.2
protein phosphatase 1 regulatory subunit 16A
chr2_+_222424520 0.11 ENST00000321276.8
sphingosine-1-phosphate phosphatase 2
chr1_-_112707314 0.11 ENST00000369642.7
ras homolog family member C
chr19_+_35666515 0.10 ENST00000617999.4
ENST00000616789.4
uroplakin 1A
chr3_-_41961989 0.10 ENST00000420927.5
ENST00000301831.9
ENST00000414606.1
unc-51 like kinase 4
chr16_+_28822982 0.10 ENST00000336783.9
ENST00000340394.12
ENST00000325215.10
ENST00000382686.8
ENST00000395547.6
ENST00000564304.5
ataxin 2 like

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.4 1.4 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.3 2.7 GO:0072733 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.3 1.4 GO:0042374 phylloquinone metabolic process(GO:0042374) phylloquinone catabolic process(GO:0042376) quinone catabolic process(GO:1901662)
0.2 1.4 GO:1904793 glial cell fate determination(GO:0007403) canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) regulation of chromatin-mediated maintenance of transcription(GO:1904499) positive regulation of chromatin-mediated maintenance of transcription(GO:1904501) regulation of euchromatin binding(GO:1904793)
0.2 0.6 GO:0070902 mitochondrial tRNA pseudouridine synthesis(GO:0070902)
0.2 0.7 GO:0060585 detection of peptidoglycan(GO:0032499) activation of MAPK activity involved in innate immune response(GO:0035419) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.2 2.4 GO:0051601 exocyst localization(GO:0051601)
0.1 0.6 GO:0045626 negative regulation of T-helper 1 cell differentiation(GO:0045626) response to odorant(GO:1990834)
0.1 0.6 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.1 0.6 GO:0045204 MAPK export from nucleus(GO:0045204)
0.1 0.3 GO:0031446 regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448)
0.1 0.9 GO:1903898 negative regulation of PERK-mediated unfolded protein response(GO:1903898) negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912)
0.1 0.4 GO:1902528 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
0.1 1.2 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.1 0.3 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.1 0.4 GO:0001757 somite specification(GO:0001757)
0.1 0.2 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.1 0.2 GO:0043049 hepatocyte cell migration(GO:0002194) otic placode formation(GO:0043049) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.1 0.3 GO:0050915 sensory perception of sour taste(GO:0050915)
0.1 0.2 GO:0014813 skeletal muscle satellite cell commitment(GO:0014813)
0.1 0.2 GO:0015917 aminophospholipid transport(GO:0015917)
0.1 0.7 GO:0034393 positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.1 1.9 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.0 0.6 GO:0072553 terminal button organization(GO:0072553)
0.0 1.2 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.0 1.1 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.7 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.7 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.0 0.2 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.1 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.0 0.2 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.0 0.3 GO:0002803 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antibacterial peptide production(GO:0002803)
0.0 0.6 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.0 0.1 GO:0034729 histone H3-K79 methylation(GO:0034729)
0.0 0.1 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.0 0.7 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 1.7 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.3 GO:1904627 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.0 0.1 GO:0060032 notochord regression(GO:0060032)
0.0 0.3 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.5 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.1 GO:1903976 negative regulation of glial cell migration(GO:1903976)
0.0 0.3 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.1 GO:1902869 regulation of amacrine cell differentiation(GO:1902869)
0.0 0.3 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.3 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.0 0.1 GO:0038033 positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway(GO:0038033)
0.0 0.1 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.0 0.1 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.0 0.1 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.0 0.2 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.0 0.3 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 1.4 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.0 0.2 GO:0002568 somatic diversification of T cell receptor genes(GO:0002568) somatic recombination of T cell receptor gene segments(GO:0002681) T cell receptor V(D)J recombination(GO:0033153)
0.0 0.4 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.4 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.1 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.0 0.2 GO:0089700 protein kinase D signaling(GO:0089700)
0.0 0.1 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.3 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.0 0.5 GO:1902259 regulation of delayed rectifier potassium channel activity(GO:1902259)
0.0 0.4 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.1 GO:0032439 endosome localization(GO:0032439) positive regulation of pinocytosis(GO:0048549)
0.0 0.1 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 0.1 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.1 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
0.0 0.1 GO:0046968 peptide antigen transport(GO:0046968)
0.0 0.1 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.0 0.1 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.0 0.1 GO:1903232 melanosome assembly(GO:1903232)
0.0 0.5 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.0 0.1 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.1 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.0 0.2 GO:0042424 catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
0.0 0.1 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.0 0.3 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.1 GO:0050893 sensory processing(GO:0050893)
0.0 0.2 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.1 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.1 GO:0019064 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.0 0.5 GO:0042092 type 2 immune response(GO:0042092)
0.0 0.3 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 0.3 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
0.0 0.5 GO:0090140 regulation of mitochondrial fission(GO:0090140)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.3 1.0 GO:0070701 mucus layer(GO:0070701)
0.2 1.4 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.1 0.4 GO:0031523 Myb complex(GO:0031523)
0.1 2.4 GO:0000145 exocyst(GO:0000145)
0.0 0.4 GO:0044294 dendritic growth cone(GO:0044294)
0.0 1.6 GO:0030904 retromer complex(GO:0030904)
0.0 0.2 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.0 0.3 GO:0097209 epidermal lamellar body(GO:0097209)
0.0 1.0 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.1 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.5 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.7 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 0.2 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.1 GO:0031085 BLOC-3 complex(GO:0031085)
0.0 2.3 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.1 GO:0032807 DNA ligase IV complex(GO:0032807)
0.0 1.9 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 1.1 GO:0030673 axolemma(GO:0030673)
0.0 0.7 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.3 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.2 GO:0005869 dynactin complex(GO:0005869)
0.0 0.4 GO:0042588 zymogen granule(GO:0042588)
0.0 0.6 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.4 GO:0031143 pseudopodium(GO:0031143)
0.0 0.3 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.3 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.2 GO:0031045 dense core granule(GO:0031045)
0.0 0.5 GO:0016592 mediator complex(GO:0016592)
0.0 0.9 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.1 GO:1990584 cardiac Troponin complex(GO:1990584)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.2 0.6 GO:0004730 pseudouridylate synthase activity(GO:0004730)
0.1 0.4 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.1 1.9 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 0.3 GO:0030305 heparanase activity(GO:0030305)
0.1 0.3 GO:0102008 cytosolic dipeptidase activity(GO:0102008)
0.1 0.7 GO:0034046 poly(G) binding(GO:0034046)
0.1 0.4 GO:0004803 transposase activity(GO:0004803)
0.1 2.7 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1 0.7 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.1 0.3 GO:0098770 FBXO family protein binding(GO:0098770)
0.1 0.6 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 0.3 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.1 1.4 GO:0070411 I-SMAD binding(GO:0070411)
0.1 1.2 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 0.3 GO:0005042 netrin receptor activity(GO:0005042)
0.1 0.3 GO:0031531 thyrotropin-releasing hormone receptor binding(GO:0031531)
0.1 0.6 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.1 GO:0070984 SET domain binding(GO:0070984)
0.0 0.7 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.7 GO:1901612 cardiolipin binding(GO:1901612)
0.0 0.2 GO:0030226 apolipoprotein receptor activity(GO:0030226)
0.0 0.2 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 0.6 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 1.0 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.0 0.4 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 1.1 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.4 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 1.6 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.1 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.2 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.0 0.4 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.1 GO:0016936 galactoside binding(GO:0016936)
0.0 0.1 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.1 GO:0004925 prolactin receptor activity(GO:0004925)
0.0 0.2 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 1.4 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.4 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.3 GO:0046625 sphingolipid binding(GO:0046625)
0.0 0.1 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.0 0.2 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.2 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.1 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0 0.6 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.4 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.3 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.2 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.0 GO:0005135 interleukin-3 receptor binding(GO:0005135)
0.0 0.1 GO:0071253 connexin binding(GO:0071253)
0.0 0.1 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.0 0.1 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.0 0.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.4 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 0.4 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.1 GO:0019826 oxygen sensor activity(GO:0019826)
0.0 0.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.4 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.3 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.2 GO:0005522 profilin binding(GO:0005522)
0.0 0.3 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 2.1 GO:0000149 SNARE binding(GO:0000149)
0.0 0.1 GO:0030172 troponin C binding(GO:0030172)
0.0 0.1 GO:0032027 myosin light chain binding(GO:0032027)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.9 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.6 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 1.4 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 1.4 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 1.9 PID IL23 PATHWAY IL23-mediated signaling events
0.0 1.2 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.1 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 1.8 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.3 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.8 PID S1P S1P3 PATHWAY S1P3 pathway
0.0 0.7 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.2 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.6 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.6 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.6 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.4 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 1.0 PID AR TF PATHWAY Regulation of Androgen receptor activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.6 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 1.3 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 1.8 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.7 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 1.2 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 2.0 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.9 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.6 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.7 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 1.1 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.7 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.7 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.4 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.4 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 0.4 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.5 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.3 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.4 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.6 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 1.4 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction