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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for RUNX1_RUNX2

Z-value: 0.84

Motif logo

Transcription factors associated with RUNX1_RUNX2

Gene Symbol Gene ID Gene Info
ENSG00000159216.19 RUNX1
ENSG00000124813.23 RUNX2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RUNX2hg38_v1_chr6_+_45328203_453283720.645.7e-04Click!
RUNX1hg38_v1_chr21_-_34888683_348887140.629.1e-04Click!

Activity profile of RUNX1_RUNX2 motif

Sorted Z-values of RUNX1_RUNX2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of RUNX1_RUNX2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr5_+_132073782 5.95 ENST00000296871.4
colony stimulating factor 2
chr1_-_173205543 3.58 ENST00000367718.5
TNF superfamily member 4
chr6_-_11382247 2.07 ENST00000397378.7
ENST00000513989.5
ENST00000508546.5
ENST00000504387.5
neural precursor cell expressed, developmentally down-regulated 9
chr21_-_35049238 1.96 ENST00000416754.1
ENST00000437180.5
ENST00000455571.5
ENST00000675419.1
RUNX family transcription factor 1
chr21_-_35049327 1.89 ENST00000300305.7
RUNX family transcription factor 1
chr11_-_128587551 1.70 ENST00000392668.8
ETS proto-oncogene 1, transcription factor
chr20_-_63568074 1.62 ENST00000427522.6
helicase with zinc finger 2
chr5_+_35856883 1.58 ENST00000506850.5
ENST00000303115.8
ENST00000511982.1
interleukin 7 receptor
chr17_+_34255274 1.50 ENST00000580907.5
ENST00000225831.4
C-C motif chemokine ligand 2
chr2_+_102418642 1.49 ENST00000264260.6
interleukin 18 receptor accessory protein
chr14_-_91253925 1.48 ENST00000531499.2
G protein-coupled receptor 68
chr12_+_14973020 1.47 ENST00000266395.3
phosphodiesterase 6H
chr5_+_126360113 1.39 ENST00000513040.5
GRAM domain containing 2B
chr1_+_206470463 1.35 ENST00000581977.7
ENST00000578328.6
ENST00000584998.5
ENST00000579827.6
inhibitor of nuclear factor kappa B kinase subunit epsilon
chr8_+_103371490 1.34 ENST00000330295.10
ENST00000415886.2
collagen triple helix repeat containing 1
chr5_-_139482285 1.29 ENST00000652110.1
stimulator of interferon response cGAMP interactor 1
chr5_-_139482173 1.27 ENST00000652271.1
stimulator of interferon response cGAMP interactor 1
chr3_-_127722562 1.24 ENST00000487473.5
ENST00000484451.1
monoglyceride lipase
chr11_-_5324297 1.24 ENST00000624187.1
olfactory receptor family 51 subfamily B member 2
chr3_-_190122317 1.22 ENST00000427335.6
prolyl 3-hydroxylase 2
chr5_-_139482341 1.20 ENST00000651699.1
stimulator of interferon response cGAMP interactor 1
chr8_-_118951876 1.20 ENST00000297350.9
TNF receptor superfamily member 11b
chr3_+_122680802 1.19 ENST00000474629.7
poly(ADP-ribose) polymerase family member 14
chr10_+_89332484 1.18 ENST00000371811.4
ENST00000680037.1
ENST00000679583.1
ENST00000679897.1
interferon induced protein with tetratricopeptide repeats 3
chr9_+_113150991 1.09 ENST00000259392.8
solute carrier family 31 member 2
chr16_+_85908988 1.07 ENST00000566369.1
interferon regulatory factor 8
chr2_+_126656128 1.07 ENST00000259254.9
ENST00000409836.3
ENST00000356887.12
glycophorin C (Gerbich blood group)
chr19_-_49155130 1.04 ENST00000595625.1
histidine rich calcium binding protein
chr12_+_121132869 1.02 ENST00000328963.10
purinergic receptor P2X 7
chr10_+_89392546 0.98 ENST00000546318.2
ENST00000371804.4
interferon induced protein with tetratricopeptide repeats 1
chr6_-_137219028 0.98 ENST00000647124.1
ENST00000642390.1
ENST00000645753.1
ENST00000646036.1
ENST00000646898.1
ENST00000644894.1
interferon gamma receptor 1
chr11_+_35176696 0.98 ENST00000528455.5
CD44 molecule (Indian blood group)
chr11_+_35176575 0.96 ENST00000526000.6
CD44 molecule (Indian blood group)
chr11_+_35176611 0.96 ENST00000279452.10
CD44 molecule (Indian blood group)
chr2_-_224982420 0.94 ENST00000645028.1
dedicator of cytokinesis 10
chr13_+_49496355 0.94 ENST00000496612.5
ENST00000357596.7
ENST00000485919.5
ENST00000442195.5
PHD finger protein 11
chr13_-_42992165 0.92 ENST00000398762.7
ENST00000313640.11
ENST00000313624.12
epithelial stromal interaction 1
chr11_+_35176639 0.91 ENST00000527889.6
CD44 molecule (Indian blood group)
chr3_-_128052166 0.89 ENST00000648300.1
monoglyceride lipase
chr17_+_76376581 0.89 ENST00000591651.5
ENST00000545180.5
sphingosine kinase 1
chr8_-_133060347 0.87 ENST00000427060.6
Src like adaptor
chr17_-_63699730 0.87 ENST00000578061.5
LIM domain containing 2
chr17_-_20467535 0.86 ENST00000324290.5
ENST00000423676.8
galectin 9B
chr8_+_103372388 0.85 ENST00000520337.1
collagen triple helix repeat containing 1
chr22_-_41285868 0.85 ENST00000422838.1
ENST00000405486.5
Ran GTPase activating protein 1
chr1_-_32870775 0.85 ENST00000649537.2
ENST00000373471.9
fibronectin type III domain containing 5
chr9_+_100427123 0.83 ENST00000395067.7
Myb/SANT DNA binding domain containing 3
chr6_+_29100609 0.80 ENST00000377171.3
olfactory receptor family 2 subfamily J member 1
chr6_+_31575557 0.79 ENST00000449264.3
tumor necrosis factor
chr15_+_67125707 0.79 ENST00000540846.6
SMAD family member 3
chr9_+_100427254 0.79 ENST00000374885.5
Myb/SANT DNA binding domain containing 3
chr1_+_205256189 0.78 ENST00000329800.7
transmembrane and coiled-coil domain family 2
chr6_+_31586680 0.77 ENST00000339530.8
leukocyte specific transcript 1
chr6_+_45328203 0.77 ENST00000371432.7
ENST00000647337.2
ENST00000371438.5
RUNX family transcription factor 2
chr2_+_201132769 0.77 ENST00000494258.5
CASP8 and FADD like apoptosis regulator
chr14_+_22281097 0.77 ENST00000390465.2
T cell receptor alpha variable 38-2/delta variable 8
chr11_+_94128834 0.76 ENST00000227638.8
ENST00000436171.2
pannexin 1
chr22_+_24607638 0.76 ENST00000432867.5
gamma-glutamyltransferase 1
chr6_-_137219340 0.74 ENST00000367739.9
ENST00000458076.5
ENST00000414770.5
interferon gamma receptor 1
chr2_-_162318129 0.73 ENST00000679938.1
interferon induced with helicase C domain 1
chr4_-_7434895 0.73 ENST00000319098.7
prosaposin like 1
chr11_-_72674394 0.72 ENST00000418754.6
ENST00000334456.10
ENST00000542969.2
phosphodiesterase 2A
chr16_-_28610032 0.72 ENST00000567512.1
sulfotransferase family 1A member 1
chr3_-_151203201 0.71 ENST00000480322.1
ENST00000309180.6
G protein-coupled receptor 171
chr17_-_1187294 0.71 ENST00000544583.6
ABR activator of RhoGEF and GTPase
chr3_+_50246888 0.69 ENST00000451956.1
G protein subunit alpha i2
chr10_+_102395693 0.67 ENST00000652277.1
ENST00000189444.11
ENST00000661543.1
nuclear factor kappa B subunit 2
chr3_+_190615308 0.67 ENST00000412080.1
interleukin 1 receptor accessory protein
chr5_-_35938572 0.67 ENST00000651391.1
ENST00000397366.5
ENST00000513623.5
ENST00000514524.2
ENST00000397367.6
calcyphosine like
chr11_+_102317450 0.66 ENST00000615299.4
ENST00000527309.2
ENST00000526421.6
ENST00000263464.9
baculoviral IAP repeat containing 3
chr8_-_139654330 0.66 ENST00000647605.1
potassium two pore domain channel subfamily K member 9
chr2_+_102337148 0.66 ENST00000311734.6
ENST00000409584.5
interleukin 1 receptor like 1
chr1_-_209651291 0.65 ENST00000391911.5
ENST00000415782.1
laminin subunit beta 3
chr12_-_49069970 0.64 ENST00000301068.11
RHEB like 1
chr6_+_14117764 0.64 ENST00000379153.4
CD83 molecule
chr11_-_72794032 0.63 ENST00000334805.11
StAR related lipid transfer domain containing 10
chr6_+_36676455 0.63 ENST00000615513.4
cyclin dependent kinase inhibitor 1A
chr12_+_112906777 0.62 ENST00000452357.7
ENST00000445409.7
2'-5'-oligoadenylate synthetase 1
chr6_+_36676489 0.62 ENST00000448526.6
cyclin dependent kinase inhibitor 1A
chr6_-_37257622 0.62 ENST00000650812.1
ENST00000497775.1
ENST00000478262.2
ENST00000356757.7
novel transmembrane protein
transmembrane protein 217
chr20_-_31723902 0.62 ENST00000676942.1
ENST00000450273.2
ENST00000678563.1
ENST00000456404.6
ENST00000420488.6
ENST00000439267.2
BCL2 like 1
chr1_-_173207322 0.62 ENST00000281834.4
TNF superfamily member 4
chr14_+_21918161 0.61 ENST00000390439.2
T cell receptor alpha variable 13-2
chr6_+_26440472 0.61 ENST00000494393.5
ENST00000482451.5
ENST00000471353.5
ENST00000361232.7
ENST00000487627.5
ENST00000496719.1
ENST00000244519.7
ENST00000490254.5
ENST00000487272.1
butyrophilin subfamily 3 member A3
chr10_+_102394488 0.61 ENST00000369966.8
nuclear factor kappa B subunit 2
chr19_+_41262656 0.60 ENST00000599719.5
ENST00000601309.5
heterogeneous nuclear ribonucleoprotein U like 1
chr17_+_18476737 0.60 ENST00000581545.5
ENST00000582333.5
ENST00000328114.11
ENST00000583322.5
ENST00000584941.5
galectin 9C
chr14_-_54902807 0.60 ENST00000543643.6
ENST00000536224.2
ENST00000395514.5
ENST00000491895.7
GTP cyclohydrolase 1
chr19_-_49155384 0.59 ENST00000252825.9
histidine rich calcium binding protein
chr6_-_37257643 0.59 ENST00000651039.1
ENST00000652495.1
ENST00000652218.1
transmembrane protein 217
chr3_-_99850976 0.58 ENST00000487087.5
filamin A interacting protein 1 like
chrX_+_68829009 0.58 ENST00000204961.5
ephrin B1
chr6_-_37257590 0.58 ENST00000336655.7
transmembrane protein 217
chr19_-_47471886 0.58 ENST00000236877.11
ENST00000597014.1
solute carrier family 8 member A2
chrX_+_9463272 0.58 ENST00000407597.7
ENST00000380961.5
ENST00000424279.6
transducin beta like 1 X-linked
chr19_-_2151525 0.58 ENST00000345016.9
ENST00000643116.3
adaptor related protein complex 3 subunit delta 1
chr1_+_172659095 0.57 ENST00000367721.3
ENST00000340030.4
Fas ligand
chr6_+_36678699 0.57 ENST00000405375.5
ENST00000244741.10
ENST00000373711.3
cyclin dependent kinase inhibitor 1A
chr2_-_228181669 0.57 ENST00000392056.8
SPHK1 interactor, AKAP domain containing
chr21_-_36542600 0.56 ENST00000399136.5
claudin 14
chr20_+_33079640 0.56 ENST00000375483.4
BPI fold containing family B member 4
chr3_-_187736493 0.56 ENST00000232014.8
BCL6 transcription repressor
chrY_-_2500895 0.55 ENST00000461691.6_PAR_Y
ENST00000381222.8_PAR_Y
ENST00000381223.9_PAR_Y
ENST00000652001.1_PAR_Y
ENST00000412516.7_PAR_Y
ENST00000334651.11_PAR_Y
zinc finger BED-type containing 1
dehydrogenase/reductase X-linked
chr1_-_247758680 0.55 ENST00000408896.4
olfactory receptor family 1 subfamily C member 1
chr14_-_91244508 0.55 ENST00000535815.5
ENST00000529102.1
G protein-coupled receptor 68
chrX_-_2500895 0.55 ENST00000461691.6
ENST00000381222.8
ENST00000381223.9
ENST00000652001.1
ENST00000412516.7
ENST00000334651.11
zinc finger BED-type containing 1
dehydrogenase/reductase X-linked
chr16_+_84768246 0.55 ENST00000569925.1
ENST00000567526.1
ubiquitin specific peptidase 10
chr22_-_45240859 0.54 ENST00000336156.10
KIAA0930
chr1_-_223363337 0.54 ENST00000608996.5
sushi domain containing 4
chr1_+_172452885 0.54 ENST00000367725.4
chromosome 1 open reading frame 105
chr1_+_167721954 0.53 ENST00000359523.7
ENST00000392121.7
ENST00000474859.5
myelin protein zero like 1
chr16_+_30023198 0.53 ENST00000681219.1
ENST00000300575.6
chromosome 16 open reading frame 92
chr7_-_105679089 0.53 ENST00000477775.5
ataxin 7 like 1
chr12_-_49904217 0.53 ENST00000550635.6
Fas apoptotic inhibitory molecule 2
chr2_+_201129318 0.53 ENST00000417748.1
CASP8 and FADD like apoptosis regulator
chr2_+_202073282 0.52 ENST00000459709.5
KIAA2012
chr22_+_21642287 0.52 ENST00000248958.5
stromal cell derived factor 2 like 1
chr2_+_202073249 0.52 ENST00000498697.3
KIAA2012
chr11_+_55885920 0.51 ENST00000244891.3
tripartite motif-containing 51
chr4_+_88378842 0.51 ENST00000264346.12
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chr17_+_19378476 0.51 ENST00000395604.8
ENST00000482850.1
mitogen-activated protein kinase 7
chr19_-_46746421 0.51 ENST00000263280.11
striatin 4
chr19_-_46788586 0.51 ENST00000542575.6
solute carrier family 1 member 5
chr17_+_27631148 0.51 ENST00000313648.10
ENST00000395473.7
ENST00000577392.5
ENST00000584661.5
galectin 9
chr14_+_21990357 0.50 ENST00000390444.1
T cell receptor alpha variable 16
chr2_+_238426920 0.50 ENST00000264607.9
ankyrin repeat and SOCS box containing 1
chr19_+_49361783 0.50 ENST00000594268.1
dickkopf like acrosomal protein 1
chr6_+_31586124 0.50 ENST00000418507.6
ENST00000376096.5
ENST00000376099.5
ENST00000376110.7
leukocyte specific transcript 1
chr2_-_207167220 0.49 ENST00000421199.5
ENST00000457962.5
Kruppel like factor 7
chr2_+_135741717 0.49 ENST00000415164.5
UBX domain protein 4
chr4_+_88378733 0.49 ENST00000273960.7
ENST00000380265.9
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chr3_-_37174578 0.48 ENST00000336686.9
LRR binding FLII interacting protein 2
chr11_+_61950370 0.48 ENST00000449131.6
bestrophin 1
chr2_+_201129483 0.48 ENST00000440180.5
CASP8 and FADD like apoptosis regulator
chr4_+_8229170 0.48 ENST00000511002.6
SH3 domain and tetratricopeptide repeats 1
chr11_-_2929412 0.48 ENST00000314222.5
pleckstrin homology like domain family A member 2
chr15_-_100341899 0.47 ENST00000568565.2
ENST00000268070.9
ADAM metallopeptidase with thrombospondin type 1 motif 17
chr3_-_186362223 0.47 ENST00000265022.8
diacylglycerol kinase gamma
chr17_+_80991824 0.47 ENST00000325167.9
charged multivesicular body protein 6
chr3_-_71130963 0.47 ENST00000649695.2
forkhead box P1
chr8_+_53851786 0.47 ENST00000297313.8
ENST00000344277.10
regulator of G protein signaling 20
chr7_+_120988683 0.47 ENST00000340646.9
ENST00000310396.10
cadherin like and PC-esterase domain containing 1
chr3_-_71130892 0.46 ENST00000491238.7
ENST00000674446.1
forkhead box P1
chr15_-_55319107 0.46 ENST00000565225.1
ENST00000436697.3
ENST00000567948.1
ENST00000563262.5
PIGB opposite strand 1
RAB27A, member RAS oncogene family
chr9_-_127778659 0.46 ENST00000314830.13
SH2 domain containing 3C
chr3_-_71130557 0.46 ENST00000497355.7
forkhead box P1
chr12_+_112906949 0.45 ENST00000679971.1
ENST00000675868.2
ENST00000550883.2
ENST00000553152.2
ENST00000202917.10
ENST00000679467.1
ENST00000680659.1
ENST00000540589.3
ENST00000552526.2
ENST00000681228.1
ENST00000680934.1
ENST00000681700.1
ENST00000679987.1
2'-5'-oligoadenylate synthetase 1
chr12_+_128853462 0.45 ENST00000281703.11
ENST00000442111.6
glycosyltransferase 1 domain containing 1
chr18_+_58149314 0.45 ENST00000435432.6
ENST00000357895.9
ENST00000586263.5
NEDD4 like E3 ubiquitin protein ligase
chr7_-_116030735 0.45 ENST00000393485.5
transcription factor EC
chr15_+_83447411 0.44 ENST00000324537.5
SH3 domain containing GRB2 like 3, endophilin A3
chr1_-_183653307 0.44 ENST00000308641.6
apolipoprotein B mRNA editing enzyme catalytic polypeptide like 4
chr15_-_50114491 0.44 ENST00000559829.5
ATPase phospholipid transporting 8B4 (putative)
chr6_+_79631322 0.44 ENST00000369838.6
SH3 domain binding glutamate rich protein like 2
chr11_+_61950343 0.44 ENST00000378043.9
bestrophin 1
chr4_+_70226116 0.44 ENST00000317987.6
follicular dendritic cell secreted protein
chr19_-_47471847 0.43 ENST00000594353.1
ENST00000542837.2
solute carrier family 8 member A2
chr17_+_34319427 0.43 ENST00000394620.2
C-C motif chemokine ligand 8
chr1_-_120051714 0.43 ENST00000579475.7
notch receptor 2
chr1_+_209686173 0.43 ENST00000615289.4
ENST00000367028.6
ENST00000261465.5
hydroxysteroid 11-beta dehydrogenase 1
chr6_+_26365159 0.42 ENST00000532865.5
ENST00000396934.7
ENST00000508906.6
ENST00000530653.5
ENST00000527417.5
butyrophilin subfamily 3 member A2
chr12_+_57434778 0.42 ENST00000309668.3
inhibin subunit beta C
chr5_+_141373878 0.42 ENST00000517434.3
ENST00000610583.1
protocadherin gamma subfamily A, 6
chr16_+_56932134 0.42 ENST00000439977.7
ENST00000300302.9
ENST00000344114.8
ENST00000379792.6
homocysteine inducible ER protein with ubiquitin like domain 1
chr6_+_31586269 0.42 ENST00000438075.7
leukocyte specific transcript 1
chr6_-_114343012 0.42 ENST00000312719.10
heparan sulfate-glucosamine 3-sulfotransferase 5
chr11_+_71998892 0.42 ENST00000393705.8
ENST00000393703.9
ENST00000337131.9
ENST00000620017.4
ENST00000531053.5
ENST00000404792.5
interleukin 18 binding protein
chr5_+_68292562 0.41 ENST00000523872.1
phosphoinositide-3-kinase regulatory subunit 1
chr18_+_13611910 0.41 ENST00000590308.1
low density lipoprotein receptor class A domain containing 4
chr12_+_123973197 0.41 ENST00000392404.7
ENST00000337815.9
ENST00000538932.6
ENST00000618862.2
ENST00000389727.8
zinc finger protein 664
novel protein
refilin A
chr19_+_10655023 0.41 ENST00000590009.5
interleukin enhancer binding factor 3
chr7_-_75772172 0.41 ENST00000005180.9
C-C motif chemokine ligand 26
chr6_+_36954729 0.40 ENST00000373674.4
peptidase inhibitor 16
chr22_-_43015133 0.40 ENST00000453643.5
ENST00000263246.8
protein kinase C and casein kinase substrate in neurons 2
chr11_+_1099730 0.40 ENST00000674892.1
mucin 2, oligomeric mucus/gel-forming
chr2_-_216013582 0.40 ENST00000620139.4
melanoregulin
chr11_-_117828698 0.40 ENST00000528014.5
FXYD domain containing ion transport regulator 2
chr10_+_84424919 0.40 ENST00000543283.2
ENST00000494586.5
coiled-coil serine rich protein 2
chr3_+_119468952 0.40 ENST00000476573.5
ENST00000295588.9
protein O-glucosyltransferase 1
chr19_-_40218339 0.39 ENST00000311308.6
tetratricopeptide repeat domain 9B
chr15_+_73684204 0.39 ENST00000537340.6
ENST00000318424.9
CD276 molecule
chr10_-_73625951 0.39 ENST00000433394.1
ENST00000422491.7
ubiquitin specific peptidase 54
chr3_+_41199462 0.39 ENST00000647264.1
ENST00000645900.1
ENST00000646174.1
ENST00000643992.1
ENST00000647390.1
ENST00000642886.1
catenin beta 1
chr22_-_50085414 0.39 ENST00000311597.10
modulator of VRAC current 1
chr9_+_99105098 0.39 ENST00000374990.6
ENST00000374994.9
ENST00000552516.5
transforming growth factor beta receptor 1
chr16_-_87936529 0.39 ENST00000649794.3
ENST00000649158.1
ENST00000648177.1
carbonic anhydrase 5A
chr12_+_48978313 0.39 ENST00000293549.4
Wnt family member 1
chr22_+_23696400 0.39 ENST00000452208.1
ral guanine nucleotide dissociation stimulator like 4
chr3_+_39051990 0.38 ENST00000302313.10
WD repeat domain 48
chr18_-_28177934 0.38 ENST00000676445.1
cadherin 2
chr2_+_168802610 0.38 ENST00000397206.6
ENST00000317647.12
ENST00000397209.6
nitric oxide synthase trafficking
chr17_+_6756035 0.38 ENST00000361842.8
ENST00000574907.5
XIAP associated factor 1
chr3_+_155083523 0.38 ENST00000680057.1
membrane metalloendopeptidase
chr8_-_23069012 0.38 ENST00000347739.3
ENST00000276431.9
TNF receptor superfamily member 10b
chr1_+_149899618 0.38 ENST00000369150.1
bolA family member 1
chr6_+_150721073 0.38 ENST00000358517.6
pleckstrin homology and RhoGEF domain containing G1
chr19_+_49363923 0.37 ENST00000597546.1
dickkopf like acrosomal protein 1
chr2_+_201129826 0.37 ENST00000457277.5
CASP8 and FADD like apoptosis regulator
chr5_+_172959511 0.37 ENST00000519522.1
ribosomal protein L26 like 1
chr17_+_48107743 0.37 ENST00000359238.7
ENST00000582104.5
ENST00000584335.5
sorting nexin 11

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.2 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
1.1 5.7 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.6 1.8 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.5 1.6 GO:1901899 positive regulation of relaxation of cardiac muscle(GO:1901899)
0.5 1.4 GO:2000502 negative regulation of natural killer cell chemotaxis(GO:2000502)
0.4 0.8 GO:0060557 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.3 1.0 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.3 1.3 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.3 2.2 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.3 0.9 GO:0046521 sphingoid catabolic process(GO:0046521)
0.3 3.8 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.2 4.0 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.2 0.7 GO:0071962 mitotic sister chromatid cohesion, centromeric(GO:0071962)
0.2 2.1 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.2 0.7 GO:2000562 negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.2 1.9 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.2 2.3 GO:1903943 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.2 0.8 GO:1904116 response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117)
0.2 0.8 GO:0030821 negative regulation of cyclic nucleotide catabolic process(GO:0030806) negative regulation of cAMP catabolic process(GO:0030821)
0.2 0.6 GO:0018395 peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine(GO:0018395) histone arginine demethylation(GO:0070077) histone H3-R2 demethylation(GO:0070078) histone H4-R3 demethylation(GO:0070079)
0.2 0.6 GO:0036466 synaptic vesicle recycling via endosome(GO:0036466)
0.2 1.3 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.2 1.8 GO:1904996 positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
0.2 0.7 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.2 1.9 GO:0090400 stress-induced premature senescence(GO:0090400)
0.2 1.4 GO:0014916 regulation of lung blood pressure(GO:0014916)
0.2 0.5 GO:0061184 positive regulation of dermatome development(GO:0061184)
0.2 0.3 GO:0002215 defense response to nematode(GO:0002215)
0.2 1.3 GO:0042483 negative regulation of odontogenesis(GO:0042483)
0.2 0.6 GO:2000863 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.2 0.6 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.2 0.5 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.2 0.6 GO:0034239 macrophage fusion(GO:0034238) regulation of macrophage fusion(GO:0034239) positive regulation of macrophage fusion(GO:0034241)
0.2 0.5 GO:0060720 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.2 0.9 GO:1904501 glial cell fate determination(GO:0007403) canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) regulation of chromatin-mediated maintenance of transcription(GO:1904499) positive regulation of chromatin-mediated maintenance of transcription(GO:1904501) regulation of euchromatin binding(GO:1904793)
0.1 0.4 GO:1904808 regulation of protein oxidation(GO:1904806) positive regulation of protein oxidation(GO:1904808)
0.1 0.7 GO:0034344 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.1 0.3 GO:1905073 occluding junction disassembly(GO:1905071) regulation of occluding junction disassembly(GO:1905073) positive regulation of occluding junction disassembly(GO:1905075)
0.1 0.4 GO:1903004 flavin adenine dinucleotide metabolic process(GO:0072387) regulation of protein K63-linked deubiquitination(GO:1903004) positive regulation of protein K63-linked deubiquitination(GO:1903006)
0.1 1.2 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.1 0.4 GO:0061182 negative regulation of chondrocyte development(GO:0061182)
0.1 0.7 GO:0032764 negative regulation of mast cell cytokine production(GO:0032764)
0.1 0.4 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.1 0.5 GO:1903803 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.1 0.4 GO:1990764 regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
0.1 0.6 GO:0015692 lead ion transport(GO:0015692)
0.1 0.1 GO:0097252 oligodendrocyte apoptotic process(GO:0097252)
0.1 0.2 GO:0043974 histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674)
0.1 1.0 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.1 0.5 GO:1904640 response to methionine(GO:1904640)
0.1 0.6 GO:0048388 endosomal lumen acidification(GO:0048388)
0.1 0.3 GO:0001545 primary ovarian follicle growth(GO:0001545)
0.1 0.6 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
0.1 0.2 GO:0002445 type IIa hypersensitivity(GO:0001794) regulation of type IIa hypersensitivity(GO:0001796) type II hypersensitivity(GO:0002445) regulation of type II hypersensitivity(GO:0002892)
0.1 0.2 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.1 0.3 GO:0007518 myoblast fate determination(GO:0007518)
0.1 0.3 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
0.1 0.3 GO:0071626 mastication(GO:0071626) learned vocalization behavior(GO:0098583)
0.1 0.8 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.1 0.3 GO:1904637 response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
0.1 0.4 GO:0090427 activation of meiosis(GO:0090427)
0.1 0.3 GO:0090133 mesendoderm migration(GO:0090133) cell migration involved in mesendoderm migration(GO:0090134)
0.1 0.5 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.1 0.4 GO:0060355 positive regulation of cell adhesion molecule production(GO:0060355)
0.1 0.8 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.1 1.4 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 0.4 GO:0036483 neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0036483) regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903381) negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903382)
0.1 0.2 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.1 0.1 GO:1902227 negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973)
0.1 1.1 GO:0030321 transepithelial chloride transport(GO:0030321)
0.1 0.5 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.1 0.3 GO:0032581 ER-dependent peroxisome organization(GO:0032581)
0.1 0.3 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.1 1.2 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.1 0.3 GO:0030035 microspike assembly(GO:0030035)
0.1 0.4 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 0.3 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.1 0.2 GO:0019046 release from viral latency(GO:0019046)
0.1 0.2 GO:0097473 cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473) retinal cell apoptotic process(GO:1990009)
0.1 1.4 GO:0072619 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.1 0.3 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.1 0.1 GO:0070352 positive regulation of white fat cell proliferation(GO:0070352)
0.1 0.2 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.1 0.5 GO:0043316 cytotoxic T cell degranulation(GO:0043316) positive regulation of constitutive secretory pathway(GO:1903435)
0.1 0.2 GO:0048162 preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162)
0.1 0.4 GO:1903413 cellular response to bile acid(GO:1903413)
0.1 0.2 GO:0070346 positive regulation of fat cell proliferation(GO:0070346)
0.1 0.7 GO:0071492 cellular response to UV-A(GO:0071492)
0.1 0.3 GO:0050902 leukocyte adhesive activation(GO:0050902)
0.1 0.2 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.1 0.2 GO:2000642 negative regulation of early endosome to late endosome transport(GO:2000642)
0.1 0.2 GO:0048058 compound eye corneal lens development(GO:0048058)
0.1 0.5 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.1 0.3 GO:0002774 Fc receptor mediated inhibitory signaling pathway(GO:0002774)
0.1 0.3 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.1 0.3 GO:0021779 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.1 0.2 GO:0009106 lipoate metabolic process(GO:0009106)
0.1 0.3 GO:2001226 negative regulation of chloride transport(GO:2001226)
0.1 0.1 GO:0060166 olfactory pit development(GO:0060166)
0.1 0.2 GO:0061573 endoplasmic reticulum polarization(GO:0061163) actin filament bundle retrograde transport(GO:0061573) actin filament bundle distribution(GO:0070650)
0.1 0.3 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.1 0.2 GO:0044278 cell wall disruption in other organism(GO:0044278)
0.1 1.3 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 0.9 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.1 0.6 GO:0002051 osteoblast fate commitment(GO:0002051)
0.1 0.1 GO:1900186 negative regulation of clathrin-mediated endocytosis(GO:1900186)
0.1 1.8 GO:0072584 caveolin-mediated endocytosis(GO:0072584)
0.1 0.8 GO:0019344 cysteine biosynthetic process(GO:0019344)
0.1 0.1 GO:0034635 glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
0.1 0.2 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
0.1 1.3 GO:0072643 interferon-gamma secretion(GO:0072643)
0.1 1.1 GO:0044130 negative regulation of growth of symbiont in host(GO:0044130)
0.1 0.2 GO:0046271 phenylpropanoid catabolic process(GO:0046271)
0.1 0.4 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.1 0.2 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.1 0.2 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.1 0.2 GO:0036079 GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
0.1 0.6 GO:0032782 bile acid secretion(GO:0032782)
0.1 0.2 GO:0009436 glyoxylate catabolic process(GO:0009436)
0.1 0.2 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.1 0.4 GO:0010813 neuropeptide catabolic process(GO:0010813)
0.1 0.2 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 0.1 GO:2001204 regulation of osteoclast development(GO:2001204)
0.1 0.6 GO:1902525 regulation of protein monoubiquitination(GO:1902525)
0.1 0.4 GO:0032439 endosome localization(GO:0032439)
0.1 0.2 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.1 0.2 GO:1904744 positive regulation of telomeric DNA binding(GO:1904744)
0.1 1.2 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.1 0.3 GO:1904566 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.1 0.1 GO:1901873 regulation of post-translational protein modification(GO:1901873)
0.1 0.2 GO:0001189 RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
0.1 0.2 GO:0044691 tooth eruption(GO:0044691)
0.1 1.3 GO:0006068 ethanol catabolic process(GO:0006068)
0.1 0.2 GO:0002325 natural killer cell differentiation involved in immune response(GO:0002325) negative regulation of natural killer cell differentiation(GO:0032824) regulation of natural killer cell differentiation involved in immune response(GO:0032826) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827)
0.1 0.7 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.1 0.8 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.1 GO:1904616 regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616)
0.0 0.4 GO:0010835 regulation of protein ADP-ribosylation(GO:0010835)
0.0 0.3 GO:0006824 cobalt ion transport(GO:0006824)
0.0 0.4 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.0 0.1 GO:0045917 positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
0.0 1.3 GO:0010884 positive regulation of lipid storage(GO:0010884)
0.0 0.2 GO:0001555 oocyte growth(GO:0001555)
0.0 1.8 GO:0060334 regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 1.0 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.2 GO:0071673 positive regulation of smooth muscle cell chemotaxis(GO:0071673)
0.0 0.1 GO:0099558 maintenance of synapse structure(GO:0099558)
0.0 1.8 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.0 0.3 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 0.1 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.0 0.2 GO:0097325 melanocyte proliferation(GO:0097325)
0.0 0.2 GO:0097476 spinal cord motor neuron migration(GO:0097476)
0.0 0.1 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.0 0.1 GO:0009386 translational attenuation(GO:0009386)
0.0 0.1 GO:0071104 response to interleukin-9(GO:0071104)
0.0 0.1 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.0 0.2 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.0 0.1 GO:0097272 ammonia homeostasis(GO:0097272) urea homeostasis(GO:0097274)
0.0 0.3 GO:0010454 negative regulation of cell fate commitment(GO:0010454)
0.0 0.1 GO:0044336 canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.0 0.6 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.4 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.0 0.2 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.0 1.0 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.3 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.0 0.2 GO:0042159 lipoprotein catabolic process(GO:0042159)
0.0 0.4 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.0 0.1 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.0 0.1 GO:0060437 lung growth(GO:0060437)
0.0 0.8 GO:0032703 negative regulation of interleukin-2 production(GO:0032703)
0.0 0.3 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.0 0.4 GO:1903142 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.0 0.2 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0 0.4 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.2 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.0 0.9 GO:1900116 extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0 0.1 GO:0001978 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) baroreceptor response to increased systemic arterial blood pressure(GO:0001983)
0.0 0.4 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.2 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.4 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.0 0.2 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.0 0.1 GO:0090107 regulation of high-density lipoprotein particle assembly(GO:0090107)
0.0 0.1 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.2 GO:0006051 mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
0.0 0.8 GO:0060742 epithelial cell differentiation involved in prostate gland development(GO:0060742)
0.0 0.3 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 0.1 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
0.0 0.7 GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.0 0.5 GO:0045217 cell-cell junction maintenance(GO:0045217)
0.0 0.1 GO:1904383 response to sodium phosphate(GO:1904383)
0.0 0.3 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.0 0.5 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 0.4 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.0 0.2 GO:0001712 ectoderm formation(GO:0001705) ectodermal cell fate commitment(GO:0001712)
0.0 0.6 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.1 GO:0033082 regulation of extrathymic T cell differentiation(GO:0033082) sebum secreting cell proliferation(GO:1990654)
0.0 0.5 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.1 GO:0035964 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 0.1 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.0 0.1 GO:0098957 anterograde axonal transport of mitochondrion(GO:0098957)
0.0 0.3 GO:0060715 syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715)
0.0 0.2 GO:0003164 His-Purkinje system development(GO:0003164)
0.0 0.5 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0 0.1 GO:0003290 septum secundum development(GO:0003285) atrial septum secundum morphogenesis(GO:0003290) embryonic heart tube anterior/posterior pattern specification(GO:0035054)
0.0 0.1 GO:0001812 regulation of type I hypersensitivity(GO:0001810) positive regulation of type I hypersensitivity(GO:0001812) type I hypersensitivity(GO:0016068)
0.0 0.4 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.0 0.3 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.1 GO:2000118 regulation of sodium-dependent phosphate transport(GO:2000118)
0.0 0.2 GO:0002326 B cell lineage commitment(GO:0002326)
0.0 0.6 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.3 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.1 GO:0009631 cold acclimation(GO:0009631)
0.0 0.4 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.3 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.2 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.0 0.2 GO:0034721 histone H3-K4 demethylation, trimethyl-H3-K4-specific(GO:0034721)
0.0 0.2 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0 0.1 GO:1903033 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.0 0.1 GO:0014810 positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014810)
0.0 0.2 GO:1904058 positive regulation of sensory perception of pain(GO:1904058) regulation of locomotor rhythm(GO:1904059)
0.0 0.1 GO:1901072 glucosamine-containing compound catabolic process(GO:1901072)
0.0 0.1 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.0 0.3 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.0 0.2 GO:0071105 response to interleukin-11(GO:0071105)
0.0 0.1 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.0 0.1 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.0 0.6 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.1 GO:0035625 negative regulation of epinephrine secretion(GO:0032811) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625)
0.0 0.9 GO:0095500 acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.0 0.4 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.1 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225) negative regulation of gastrulation(GO:2000542)
0.0 0.3 GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.0 0.0 GO:1901094 regulation of protein tetramerization(GO:1901090) negative regulation of protein tetramerization(GO:1901091) regulation of protein homotetramerization(GO:1901093) negative regulation of protein homotetramerization(GO:1901094)
0.0 0.2 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.0 0.1 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.0 0.2 GO:0002084 protein depalmitoylation(GO:0002084)
0.0 0.3 GO:0035585 calcium-mediated signaling using extracellular calcium source(GO:0035585)
0.0 0.4 GO:0051531 NFAT protein import into nucleus(GO:0051531)
0.0 0.2 GO:0060174 limb bud formation(GO:0060174)
0.0 0.2 GO:0010759 positive regulation of macrophage chemotaxis(GO:0010759)
0.0 0.1 GO:0070269 pyroptosis(GO:0070269)
0.0 0.3 GO:0021633 optic nerve structural organization(GO:0021633)
0.0 0.2 GO:0061052 negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
0.0 0.5 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.1 GO:0043129 surfactant homeostasis(GO:0043129)
0.0 0.3 GO:0006449 regulation of translational termination(GO:0006449)
0.0 0.1 GO:2001303 lipoxin biosynthetic process(GO:2001301) lipoxin A4 metabolic process(GO:2001302) lipoxin A4 biosynthetic process(GO:2001303)
0.0 0.1 GO:0050705 regulation of interleukin-1 alpha secretion(GO:0050705)
0.0 0.2 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.0 0.2 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 0.5 GO:1903541 regulation of exosomal secretion(GO:1903541)
0.0 0.1 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.2 GO:0042738 exogenous drug catabolic process(GO:0042738)
0.0 0.1 GO:0032595 B cell receptor transport within lipid bilayer(GO:0032595) B cell receptor transport into membrane raft(GO:0032597) protein transport out of membrane raft(GO:0032599) chemokine receptor transport out of membrane raft(GO:0032600) negative regulation of transforming growth factor beta3 production(GO:0032913) chemokine receptor transport within lipid bilayer(GO:0033606)
0.0 0.1 GO:0031438 negative regulation of mRNA cleavage(GO:0031438) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.0 0.3 GO:0033689 negative regulation of osteoblast proliferation(GO:0033689)
0.0 0.5 GO:0030539 male genitalia development(GO:0030539)
0.0 0.3 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.9 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.2 GO:0045651 positive regulation of macrophage differentiation(GO:0045651)
0.0 0.4 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.0 0.2 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.0 0.1 GO:0061300 cerebellum vasculature development(GO:0061300)
0.0 0.1 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.0 0.1 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.0 0.2 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0 0.1 GO:1905224 clathrin-coated pit assembly(GO:1905224)
0.0 0.1 GO:0070843 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
0.0 0.1 GO:0072717 cellular response to actinomycin D(GO:0072717)
0.0 0.1 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.0 0.1 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.0 0.2 GO:0071371 cellular response to gonadotropin stimulus(GO:0071371)
0.0 0.2 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.1 GO:1903301 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.0 0.2 GO:0010745 negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.0 0.2 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.0 0.1 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 0.4 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.4 GO:0045116 protein neddylation(GO:0045116)
0.0 1.5 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.1 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0 0.2 GO:0060368 regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368)
0.0 0.3 GO:0034501 protein localization to kinetochore(GO:0034501) kinetochore assembly(GO:0051382)
0.0 0.1 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.0 0.1 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.0 0.1 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.0 0.2 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0 3.3 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.1 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.0 0.0 GO:0072193 ureter smooth muscle development(GO:0072191) ureter smooth muscle cell differentiation(GO:0072193) mesenchymal cell proliferation involved in ureter development(GO:0072198) regulation of mesenchymal cell proliferation involved in ureter development(GO:0072199) positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.0 0.3 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.1 GO:0052331 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.0 0.0 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.0 0.2 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.1 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
0.0 0.1 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 0.2 GO:0043144 snoRNA processing(GO:0043144)
0.0 0.2 GO:0002903 negative regulation of B cell apoptotic process(GO:0002903)
0.0 1.2 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.2 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.0 0.2 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.1 GO:0060699 regulation of endoribonuclease activity(GO:0060699)
0.0 0.2 GO:0070445 oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.0 0.2 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.1 GO:0090131 mesenchyme migration(GO:0090131)
0.0 0.1 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.0 0.2 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.2 GO:0046885 regulation of hormone biosynthetic process(GO:0046885)
0.0 0.2 GO:0060850 regulation of transcription involved in cell fate commitment(GO:0060850)
0.0 0.2 GO:0033033 negative regulation of myeloid cell apoptotic process(GO:0033033)
0.0 0.3 GO:0051601 exocyst localization(GO:0051601)
0.0 1.3 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 0.4 GO:0035456 response to interferon-beta(GO:0035456)
0.0 0.1 GO:2000587 negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.0 0.1 GO:0072423 response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423)
0.0 0.1 GO:0006842 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.0 0.3 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 0.1 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.1 GO:0090069 regulation of ribosome biogenesis(GO:0090069) regulation of rRNA processing(GO:2000232)
0.0 0.2 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.1 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.0 0.5 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.2 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 0.2 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.2 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.3 GO:0032354 response to follicle-stimulating hormone(GO:0032354)
0.0 0.1 GO:0002902 regulation of B cell apoptotic process(GO:0002902)
0.0 0.1 GO:1904753 positive regulation of heart rate by epinephrine(GO:0003065) negative regulation of vascular associated smooth muscle cell migration(GO:1904753)
0.0 0.0 GO:2000053 regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053)
0.0 0.1 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.0 0.2 GO:0014894 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.1 GO:0009732 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0 0.0 GO:1903517 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208) regulation of single strand break repair(GO:1903516) negative regulation of single strand break repair(GO:1903517) negative regulation of beta-galactosidase activity(GO:1903770) telomere single strand break repair(GO:1903823) negative regulation of telomere single strand break repair(GO:1903824)
0.0 0.1 GO:1900038 negative regulation of cellular response to hypoxia(GO:1900038)
0.0 0.4 GO:0048305 immunoglobulin secretion(GO:0048305)
0.0 1.1 GO:0050672 negative regulation of mononuclear cell proliferation(GO:0032945) negative regulation of lymphocyte proliferation(GO:0050672)
0.0 0.1 GO:0001969 activation of membrane attack complex(GO:0001905) regulation of activation of membrane attack complex(GO:0001969)
0.0 0.3 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.1 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.2 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.1 GO:1902410 mitotic cytokinetic process(GO:1902410)
0.0 0.1 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.0 0.3 GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030947)
0.0 0.1 GO:0001878 response to yeast(GO:0001878)
0.0 0.2 GO:0051775 response to redox state(GO:0051775)
0.0 0.6 GO:1901998 toxin transport(GO:1901998)
0.0 0.2 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.0 0.4 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.1 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.1 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.0 GO:0036116 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.0 0.1 GO:0071918 urea transmembrane transport(GO:0071918)
0.0 0.1 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.1 GO:0010940 positive regulation of necrotic cell death(GO:0010940)
0.0 0.2 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.0 0.1 GO:0042256 mature ribosome assembly(GO:0042256)
0.0 0.1 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.0 0.2 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.7 GO:0019985 translesion synthesis(GO:0019985)
0.0 0.0 GO:0048817 negative regulation of hair follicle maturation(GO:0048817)
0.0 0.1 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.0 GO:0030885 regulation of myeloid dendritic cell activation(GO:0030885) negative regulation of myeloid dendritic cell activation(GO:0030886)
0.0 0.1 GO:0003373 dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374)
0.0 0.2 GO:0015816 glycine transport(GO:0015816)
0.0 0.0 GO:0038158 granulocyte colony-stimulating factor signaling pathway(GO:0038158)
0.0 0.1 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.2 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.2 GO:0048311 mitochondrion distribution(GO:0048311)
0.0 0.1 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.0 0.3 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.4 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.1 GO:0031053 primary miRNA processing(GO:0031053)
0.0 0.1 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.3 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 0.1 GO:0051923 sulfation(GO:0051923)
0.0 0.1 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 0.2 GO:0010763 positive regulation of fibroblast migration(GO:0010763)
0.0 0.3 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.1 GO:0071394 cellular response to testosterone stimulus(GO:0071394)
0.0 0.4 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.1 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.1 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.1 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.0 GO:0019732 antifungal humoral response(GO:0019732)
0.0 0.3 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.0 GO:0014063 negative regulation of serotonin secretion(GO:0014063)
0.0 0.1 GO:0050915 sensory perception of sour taste(GO:0050915)
0.0 0.3 GO:0051764 actin crosslink formation(GO:0051764)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.8 GO:0070557 PCNA-p21 complex(GO:0070557)
0.3 3.8 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.3 1.3 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.3 0.8 GO:1990723 cytoplasmic periphery of the nuclear pore complex(GO:1990723)
0.2 1.8 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.1 0.9 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.1 0.5 GO:0005595 collagen type XII trimer(GO:0005595)
0.1 0.5 GO:0044393 microspike(GO:0044393)
0.1 0.6 GO:0070826 paraferritin complex(GO:0070826)
0.1 0.9 GO:0031415 NatA complex(GO:0031415)
0.1 1.9 GO:0032059 bleb(GO:0032059)
0.1 0.3 GO:0070701 mucus layer(GO:0070701)
0.1 0.4 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.1 0.4 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.1 2.1 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.1 0.8 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 0.6 GO:0005610 laminin-5 complex(GO:0005610)
0.1 0.2 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.1 1.2 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 0.5 GO:0044530 supraspliceosomal complex(GO:0044530)
0.1 1.0 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 0.4 GO:0005826 actomyosin contractile ring(GO:0005826)
0.1 0.2 GO:0043159 acrosomal matrix(GO:0043159)
0.1 0.2 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.1 0.4 GO:1990037 Lewy body core(GO:1990037)
0.1 0.4 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.1 0.7 GO:0097524 sperm plasma membrane(GO:0097524)
0.1 0.2 GO:0030689 Noc complex(GO:0030689)
0.1 0.3 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 0.3 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.2 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 0.2 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.0 0.8 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.2 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
0.0 0.7 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.4 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.1 GO:1990423 RZZ complex(GO:1990423)
0.0 0.2 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.0 0.4 GO:0060091 kinocilium(GO:0060091)
0.0 0.4 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.4 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.2 GO:0072534 perineuronal net(GO:0072534)
0.0 0.4 GO:0016600 flotillin complex(GO:0016600)
0.0 0.6 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.2 GO:0019815 B cell receptor complex(GO:0019815)
0.0 0.2 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.0 0.6 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.2 GO:0045160 myosin I complex(GO:0045160)
0.0 0.3 GO:0097208 alveolar lamellar body(GO:0097208)
0.0 0.4 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.1 GO:0044301 climbing fiber(GO:0044301)
0.0 0.1 GO:0034455 t-UTP complex(GO:0034455)
0.0 0.4 GO:0016342 catenin complex(GO:0016342)
0.0 0.3 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.2 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.0 0.4 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.9 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.1 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.2 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.0 0.1 GO:0071752 dimeric IgA immunoglobulin complex(GO:0071750) secretory dimeric IgA immunoglobulin complex(GO:0071752)
0.0 0.2 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.0 0.3 GO:0070187 telosome(GO:0070187)
0.0 0.4 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.5 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.2 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.5 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.2 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 0.1 GO:0070081 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.3 GO:0033010 paranodal junction(GO:0033010)
0.0 0.1 GO:0042643 actomyosin, actin portion(GO:0042643)
0.0 1.7 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.5 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.6 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.2 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.5 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.1 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.1 GO:0090661 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.0 0.1 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.1 GO:0044308 axonal spine(GO:0044308)
0.0 0.1 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 2.4 GO:0016605 PML body(GO:0016605)
0.0 0.1 GO:1903439 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.0 0.3 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.3 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 1.7 GO:0044853 plasma membrane raft(GO:0044853)
0.0 0.1 GO:0061574 ASAP complex(GO:0061574)
0.0 0.1 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.2 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.1 GO:0071439 clathrin complex(GO:0071439)
0.0 1.0 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.1 GO:0035976 AP1 complex(GO:0035976)
0.0 0.1 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.7 GO:0005771 multivesicular body(GO:0005771)
0.0 0.1 GO:0030893 meiotic cohesin complex(GO:0030893)
0.0 0.1 GO:0005879 axonemal microtubule(GO:0005879)
0.0 0.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.1 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.6 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 4.3 GO:0019898 extrinsic component of membrane(GO:0019898)
0.0 0.2 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.2 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.8 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.0 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.0 0.1 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 1.3 GO:0005913 cell-cell adherens junction(GO:0005913)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.7 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.4 1.3 GO:0008384 IkappaB kinase activity(GO:0008384)
0.4 1.5 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.4 1.8 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.3 1.0 GO:0042007 interleukin-18 binding(GO:0042007)
0.3 1.2 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797)
0.2 0.7 GO:0052858 peptidyl-lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0052858)
0.2 1.1 GO:0004803 transposase activity(GO:0004803)
0.2 0.7 GO:0002113 interleukin-33 binding(GO:0002113)
0.2 0.6 GO:0033749 histone demethylase activity (H3-R2 specific)(GO:0033746) histone demethylase activity (H4-R3 specific)(GO:0033749)
0.2 0.7 GO:0002114 interleukin-33 receptor activity(GO:0002114)
0.2 1.0 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.1 0.4 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.1 0.4 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1 0.8 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.1 0.4 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.1 0.9 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.1 0.6 GO:0015094 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.1 2.5 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 6.2 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 0.4 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.1 0.3 GO:0004963 follicle-stimulating hormone receptor activity(GO:0004963)
0.1 0.8 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.1 0.5 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.1 0.5 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.1 0.3 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.1 0.4 GO:0045569 TRAIL binding(GO:0045569)
0.1 3.8 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.3 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.1 0.3 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.1 1.0 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 0.6 GO:0048030 disaccharide binding(GO:0048030)
0.1 0.3 GO:0070984 SET domain binding(GO:0070984)
0.1 0.8 GO:0019238 cyclohydrolase activity(GO:0019238)
0.1 0.5 GO:0042835 BRE binding(GO:0042835)
0.1 2.3 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1 1.0 GO:0051434 BH3 domain binding(GO:0051434)
0.1 0.5 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 1.1 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 0.4 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 2.5 GO:0030553 cGMP binding(GO:0030553)
0.1 0.7 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 0.5 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.1 2.9 GO:0005109 frizzled binding(GO:0005109)
0.1 1.3 GO:0070411 I-SMAD binding(GO:0070411)
0.1 0.3 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 0.1 GO:0015235 cobalamin transporter activity(GO:0015235)
0.1 0.4 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 0.5 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.1 0.2 GO:0005457 GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.1 0.2 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.1 0.2 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.1 0.8 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.1 0.2 GO:0045127 N-acetylglucosamine kinase activity(GO:0045127)
0.1 1.0 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 0.4 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.1 0.3 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.1 0.3 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.1 0.7 GO:0004568 chitinase activity(GO:0004568)
0.0 0.2 GO:0051734 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0 0.2 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0 0.3 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.3 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0 0.4 GO:0038049 transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049)
0.0 0.2 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 0.8 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 1.3 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.4 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.3 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.2 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.0 0.3 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.6 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.1 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.0 0.8 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.2 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.0 0.2 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0 0.2 GO:0001626 nociceptin receptor activity(GO:0001626)
0.0 0.1 GO:0052810 1-phosphatidylinositol-5-kinase activity(GO:0052810)
0.0 0.3 GO:0035184 histone threonine kinase activity(GO:0035184)
0.0 0.4 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.0 0.2 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 0.1 GO:0030156 benzodiazepine receptor binding(GO:0030156)
0.0 0.2 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.3 GO:0023029 MHC class Ib protein binding(GO:0023029)
0.0 0.2 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.5 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.3 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.1 GO:0050294 steroid sulfotransferase activity(GO:0050294)
0.0 0.1 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.0 0.4 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.1 GO:0005011 macrophage colony-stimulating factor receptor activity(GO:0005011)
0.0 0.2 GO:0004882 androgen receptor activity(GO:0004882)
0.0 0.2 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.3 GO:0030884 lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884)
0.0 0.9 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.9 GO:0031005 filamin binding(GO:0031005)
0.0 0.2 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.3 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 0.6 GO:0008391 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.7 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.2 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 0.2 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.3 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.7 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.4 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.2 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.0 0.2 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.0 0.3 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.1 GO:0019976 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.0 0.3 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.3 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 0.1 GO:0031716 calcitonin receptor binding(GO:0031716)
0.0 0.2 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 1.8 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.1 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.0 5.6 GO:0070851 growth factor receptor binding(GO:0070851)
0.0 0.1 GO:0097363 protein O-GlcNAc transferase activity(GO:0097363)
0.0 0.4 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.1 GO:0003870 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.0 0.1 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 0.1 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165) hepoxilin-epoxide hydrolase activity(GO:0047977)
0.0 0.6 GO:0015101 organic cation transmembrane transporter activity(GO:0015101)
0.0 0.4 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 0.2 GO:0034603 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.0 0.3 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.4 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.1 GO:0047661 racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661)
0.0 0.2 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 0.2 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.1 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0 0.3 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.7 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.1 GO:0043273 CTPase activity(GO:0043273)
0.0 0.1 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.0 0.3 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.8 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.8 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.2 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.5 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.5 GO:0016502 G-protein coupled nucleotide receptor activity(GO:0001608) purinergic nucleotide receptor activity(GO:0001614) nucleotide receptor activity(GO:0016502) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.1 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.1 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.0 0.1 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.0 0.7 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.1 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.1 GO:0098808 mRNA cap binding(GO:0098808)
0.0 0.1 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.0 0.9 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.1 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.1 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.0 0.1 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.4 GO:0005372 water transmembrane transporter activity(GO:0005372)
0.0 0.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.5 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.3 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.2 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.1 GO:0097643 amylin receptor activity(GO:0097643)
0.0 0.3 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.0 3.3 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.2 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.1 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.0 0.2 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.5 GO:0031489 myosin V binding(GO:0031489)
0.0 0.2 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.4 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.8 GO:0004629 phospholipase C activity(GO:0004629)
0.0 0.1 GO:1990405 protein antigen binding(GO:1990405)
0.0 0.2 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 0.4 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.4 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.1 GO:0036033 mediator complex binding(GO:0036033)
0.0 0.1 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0 2.6 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.4 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.1 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.0 0.2 GO:1903136 cuprous ion binding(GO:1903136)
0.0 0.7 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.2 GO:0001164 RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0 0.2 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.2 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0 0.3 GO:0030275 LRR domain binding(GO:0030275)
0.0 0.6 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.1 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.0 0.6 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.1 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.0 0.2 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.1 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.1 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.0 0.3 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.2 GO:0016755 transferase activity, transferring amino-acyl groups(GO:0016755)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.3 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 0.4 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.1 GO:0050610 glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
0.0 0.1 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 1.3 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.3 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.5 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.1 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.1 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.0 0.1 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.0 0.1 GO:0005497 androgen binding(GO:0005497)
0.0 0.1 GO:0032296 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0 0.1 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.0 0.2 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.1 GO:0016936 galactoside binding(GO:0016936)
0.0 0.1 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.2 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.1 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.0 0.4 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.1 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.1 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.7 GO:0070412 R-SMAD binding(GO:0070412)
0.0 1.8 GO:0051117 ATPase binding(GO:0051117)
0.0 0.1 GO:0019158 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 1.0 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.2 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.1 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 0.3 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.4 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 2.7 GO:0001047 core promoter binding(GO:0001047)
0.0 0.3 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.3 GO:0005537 mannose binding(GO:0005537)
0.0 0.1 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.1 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.0 0.3 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.2 GO:0060590 ATPase regulator activity(GO:0060590)
0.0 0.3 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.2 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.3 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.1 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.3 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.2 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.0 GO:0071723 lipopeptide binding(GO:0071723)
0.0 0.0 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.1 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.1 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.5 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 1.8 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 0.1 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.1 4.4 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 5.1 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.1 3.4 PID IL23 PATHWAY IL23-mediated signaling events
0.1 1.2 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.1 0.1 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.1 0.4 PID TRAIL PATHWAY TRAIL signaling pathway
0.1 0.1 PID S1P S1P1 PATHWAY S1P1 pathway
0.1 2.1 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.6 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 1.7 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 3.5 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.0 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 1.4 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.6 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.8 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 1.3 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.5 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.3 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 3.0 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.2 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.3 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 1.1 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 1.2 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.6 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.7 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.5 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.5 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.3 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.1 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 0.8 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 1.0 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.7 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 1.9 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.4 PID FGF PATHWAY FGF signaling pathway
0.0 5.9 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.4 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.6 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.3 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.1 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.1 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.2 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.5 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.3 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 0.2 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.0 0.1 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 0.2 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.2 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.5 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.4 PID NCADHERIN PATHWAY N-cadherin signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.6 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 3.3 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 6.6 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.1 3.8 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 2.1 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.1 1.4 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 1.8 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.1 1.1 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.1 0.9 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.1 2.9 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 0.8 REACTOME OPSINS Genes involved in Opsins
0.1 1.5 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 5.1 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 1.8 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.6 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 1.1 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 1.1 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.3 REACTOME PLC BETA MEDIATED EVENTS Genes involved in PLC beta mediated events
0.0 0.8 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.7 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.9 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 1.1 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.7 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 1.3 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.4 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.4 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.3 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.6 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 1.0 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 1.2 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.1 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.0 0.6 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0 0.4 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 0.7 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.3 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 1.0 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 1.0 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.4 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 1.0 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.1 REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
0.0 0.5 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.3 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.6 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.4 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.8 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.2 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.1 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.0 0.7 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.8 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.3 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 2.5 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.2 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.2 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.7 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.4 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.6 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.5 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.2 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.2 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.2 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 2.6 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.0 0.2 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.9 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 0.5 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.5 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.0 REACTOME IL 2 SIGNALING Genes involved in Interleukin-2 signaling
0.0 0.1 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.4 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.1 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 0.5 REACTOME ION CHANNEL TRANSPORT Genes involved in Ion channel transport
0.0 0.8 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.1 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.4 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)