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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for RUNX3_BCL11A

Z-value: 0.68

Motif logo

Transcription factors associated with RUNX3_BCL11A

Gene Symbol Gene ID Gene Info
ENSG00000020633.19 RUNX3
ENSG00000119866.22 BCL11A

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
BCL11Ahg38_v1_chr2_-_60553409_605534610.462.0e-02Click!
RUNX3hg38_v1_chr1_-_24964984_249650200.193.6e-01Click!

Activity profile of RUNX3_BCL11A motif

Sorted Z-values of RUNX3_BCL11A motif

Network of associatons between targets according to the STRING database.

First level regulatory network of RUNX3_BCL11A

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr5_+_132073782 5.28 ENST00000296871.4
colony stimulating factor 2
chr1_+_109910485 2.57 ENST00000525659.5
colony stimulating factor 1
chr21_-_35049238 2.19 ENST00000416754.1
ENST00000437180.5
ENST00000455571.5
ENST00000675419.1
RUNX family transcription factor 1
chr21_-_35049327 2.11 ENST00000300305.7
RUNX family transcription factor 1
chr11_-_128587551 1.98 ENST00000392668.8
ETS proto-oncogene 1, transcription factor
chr2_+_227813834 1.93 ENST00000358813.5
ENST00000409189.7
C-C motif chemokine ligand 20
chr5_+_35856883 1.86 ENST00000506850.5
ENST00000303115.8
ENST00000511982.1
interleukin 7 receptor
chr15_+_67125707 1.84 ENST00000540846.6
SMAD family member 3
chr3_-_151203201 1.81 ENST00000480322.1
ENST00000309180.6
G protein-coupled receptor 171
chr1_+_109910840 1.76 ENST00000329608.11
ENST00000488198.5
colony stimulating factor 1
chr1_+_109910986 1.67 ENST00000369801.1
colony stimulating factor 1
chr2_+_102418642 1.37 ENST00000264260.6
interleukin 18 receptor accessory protein
chr6_+_45328203 1.22 ENST00000371432.7
ENST00000647337.2
ENST00000371438.5
RUNX family transcription factor 2
chr1_-_173205543 1.15 ENST00000367718.5
TNF superfamily member 4
chrX_+_68829009 1.01 ENST00000204961.5
ephrin B1
chr6_+_150721073 1.00 ENST00000358517.6
pleckstrin homology and RhoGEF domain containing G1
chr17_-_63699730 0.90 ENST00000578061.5
LIM domain containing 2
chr19_-_49155130 0.90 ENST00000595625.1
histidine rich calcium binding protein
chr5_-_139482341 0.77 ENST00000651699.1
stimulator of interferon response cGAMP interactor 1
chr12_+_121132869 0.75 ENST00000328963.10
purinergic receptor P2X 7
chr5_-_139482285 0.74 ENST00000652110.1
stimulator of interferon response cGAMP interactor 1
chr3_-_71130963 0.73 ENST00000649695.2
forkhead box P1
chr3_-_71130557 0.72 ENST00000497355.7
forkhead box P1
chr5_-_139482173 0.71 ENST00000652271.1
stimulator of interferon response cGAMP interactor 1
chr1_-_173207322 0.66 ENST00000281834.4
TNF superfamily member 4
chr3_-_71130892 0.66 ENST00000491238.7
ENST00000674446.1
forkhead box P1
chr19_+_10086787 0.65 ENST00000590378.5
ENST00000397881.7
shiftless antiviral inhibitor of ribosomal frameshifting
chr3_+_141386393 0.65 ENST00000503809.5
zinc finger and BTB domain containing 38
chr19_-_49155384 0.65 ENST00000252825.9
histidine rich calcium binding protein
chr3_-_99850976 0.63 ENST00000487087.5
filamin A interacting protein 1 like
chr12_+_75481204 0.63 ENST00000550491.1
GLI pathogenesis related 1
chr3_+_141386862 0.61 ENST00000513258.5
zinc finger and BTB domain containing 38
chr5_+_134115563 0.61 ENST00000517851.5
ENST00000521639.5
ENST00000522375.5
ENST00000378560.8
ENST00000520958.5
ENST00000518915.5
ENST00000395023.5
transcription factor 7
chr5_-_95081482 0.60 ENST00000312216.12
ENST00000512425.5
ENST00000505208.5
ENST00000429576.6
ENST00000508509.5
ENST00000510732.5
multiple C2 and transmembrane domain containing 1
chr14_+_51489112 0.59 ENST00000356218.8
FERM domain containing 6
chr7_+_30852273 0.57 ENST00000509504.2
novel protein, MINDY4 and AQP1 readthrough
chr8_-_118951876 0.53 ENST00000297350.9
TNF receptor superfamily member 11b
chr17_-_58417521 0.53 ENST00000584437.5
ENST00000407977.7
ring finger protein 43
chr15_-_55270874 0.53 ENST00000567380.5
ENST00000565972.5
ENST00000569493.5
RAB27A, member RAS oncogene family
chr7_-_116030735 0.50 ENST00000393485.5
transcription factor EC
chr3_-_190122317 0.49 ENST00000427335.6
prolyl 3-hydroxylase 2
chr17_-_58417547 0.49 ENST00000577716.5
ring finger protein 43
chr11_+_35176696 0.49 ENST00000528455.5
CD44 molecule (Indian blood group)
chr9_+_108862255 0.48 ENST00000333999.5
actin like 7A
chr19_-_42132391 0.47 ENST00000528894.8
ENST00000560804.6
ENST00000560558.5
ENST00000560398.5
ENST00000526816.6
ENST00000625670.2
POU class 2 homeobox 2
chr19_-_48993300 0.47 ENST00000323798.8
ENST00000263276.6
glycogen synthase 1
chr1_+_156369202 0.46 ENST00000537040.6
Rh family B glycoprotein
chr7_+_18495723 0.45 ENST00000681950.1
ENST00000622668.4
ENST00000405010.7
ENST00000406451.8
ENST00000441542.7
ENST00000428307.6
ENST00000681273.1
histone deacetylase 9
chr11_+_35176575 0.45 ENST00000526000.6
CD44 molecule (Indian blood group)
chr15_-_55270383 0.45 ENST00000396307.6
RAB27A, member RAS oncogene family
chr15_-_55270280 0.44 ENST00000564609.5
RAB27A, member RAS oncogene family
chr2_+_135741717 0.44 ENST00000415164.5
UBX domain protein 4
chr10_+_99659430 0.43 ENST00000370489.5
ectonucleoside triphosphate diphosphohydrolase 7
chr9_+_116153783 0.43 ENST00000328252.4
pappalysin 1
chr1_-_151826085 0.43 ENST00000356728.11
RAR related orphan receptor C
chr19_-_42132465 0.42 ENST00000529067.5
ENST00000529952.5
ENST00000342301.8
ENST00000389341.9
POU class 2 homeobox 2
chr6_+_31546845 0.42 ENST00000376146.8
NFKB inhibitor like 1
chr17_+_82237134 0.42 ENST00000583025.1
solute carrier family 16 member 3
chr11_+_35176611 0.41 ENST00000279452.10
CD44 molecule (Indian blood group)
chr3_+_114294020 0.41 ENST00000383671.8
T cell immunoreceptor with Ig and ITIM domains
chr9_-_34048868 0.41 ENST00000379239.9
ENST00000684158.1
ENST00000379238.7
ENST00000360802.6
ubiquitin associated protein 2
chr11_+_35176639 0.40 ENST00000527889.6
CD44 molecule (Indian blood group)
chrX_+_9463272 0.39 ENST00000407597.7
ENST00000380961.5
ENST00000424279.6
transducin beta like 1 X-linked
chr3_-_11568764 0.39 ENST00000424529.6
vestigial like family member 4
chr8_-_71361860 0.39 ENST00000303824.11
ENST00000645451.1
EYA transcriptional coactivator and phosphatase 1
chr17_+_20073538 0.38 ENST00000681116.1
ENST00000680572.1
ENST00000680604.1
ENST00000681875.1
ENST00000679058.1
sperm antigen with calponin homology and coiled-coil domains 1
chr12_+_14973020 0.37 ENST00000266395.3
phosphodiesterase 6H
chr16_+_84768246 0.36 ENST00000569925.1
ENST00000567526.1
ubiquitin specific peptidase 10
chr20_+_33079640 0.36 ENST00000375483.4
BPI fold containing family B member 4
chr15_+_73683938 0.35 ENST00000567189.5
CD276 molecule
chr4_+_94489030 0.35 ENST00000510099.5
PDZ and LIM domain 5
chr8_-_71362054 0.35 ENST00000340726.8
EYA transcriptional coactivator and phosphatase 1
chr2_+_74529923 0.35 ENST00000258080.8
ENST00000352222.7
HtrA serine peptidase 2
chr15_-_43618800 0.35 ENST00000450892.7
ENST00000541030.5
stereocilin
chr9_-_115091018 0.34 ENST00000542877.5
ENST00000537320.5
ENST00000341037.8
tenascin C
chr1_+_239719542 0.33 ENST00000448020.1
cholinergic receptor muscarinic 3
chr4_+_87975667 0.33 ENST00000237623.11
ENST00000682655.1
ENST00000508233.6
ENST00000360804.4
ENST00000395080.8
secreted phosphoprotein 1
chr2_+_96536743 0.33 ENST00000673792.1
ENST00000357485.8
AT-rich interaction domain 5A
chr4_+_70226116 0.33 ENST00000317987.6
follicular dendritic cell secreted protein
chr11_-_5324297 0.33 ENST00000624187.1
olfactory receptor family 51 subfamily B member 2
chr20_-_46406559 0.32 ENST00000372176.5
engulfment and cell motility 2
chr19_+_13024573 0.32 ENST00000358552.7
ENST00000360105.8
ENST00000588228.5
ENST00000676441.1
ENST00000591028.1
nuclear factor I X
chr1_-_217076889 0.32 ENST00000493748.5
ENST00000463665.5
estrogen related receptor gamma
chr15_+_68290206 0.31 ENST00000566008.1
fem-1 homolog B
chr1_-_161307420 0.31 ENST00000491222.5
ENST00000672287.2
myelin protein zero
chr10_-_13234368 0.31 ENST00000378681.8
upper zone of growth plate and cartilage matrix associated
chr20_-_46406582 0.31 ENST00000450812.5
ENST00000290246.11
ENST00000396391.5
engulfment and cell motility 2
chr6_+_144583198 0.30 ENST00000367526.8
utrophin
chr4_+_87975829 0.30 ENST00000614857.5
secreted phosphoprotein 1
chr2_+_96537254 0.29 ENST00000454558.2
AT-rich interaction domain 5A
chr10_+_25174969 0.29 ENST00000376351.4
G protein-coupled receptor 158
chr22_-_30246739 0.29 ENST00000403987.3
ENST00000249075.4
LIF interleukin 6 family cytokine
chr7_+_120988683 0.29 ENST00000340646.9
ENST00000310396.10
cadherin like and PC-esterase domain containing 1
chr21_-_30372265 0.29 ENST00000399889.4
keratin associated protein 13-2
chr5_-_35938572 0.29 ENST00000651391.1
ENST00000397366.5
ENST00000513623.5
ENST00000514524.2
ENST00000397367.6
calcyphosine like
chr8_-_133060347 0.28 ENST00000427060.6
Src like adaptor
chr12_+_107685759 0.28 ENST00000412830.8
ENST00000547995.5
PWP1 homolog, endonuclein
chr2_+_135741814 0.28 ENST00000272638.14
UBX domain protein 4
chr10_-_13234329 0.28 ENST00000463405.2
upper zone of growth plate and cartilage matrix associated
chr3_-_196287649 0.27 ENST00000441879.5
ENST00000292823.6
ENST00000431016.6
ENST00000411591.5
phosphate cytidylyltransferase 1, choline, alpha
chr7_-_116030750 0.27 ENST00000265440.12
ENST00000320239.11
transcription factor EC
chr5_+_136160986 0.27 ENST00000507637.1
SMAD family member 5
chr18_-_58629084 0.27 ENST00000361673.4
alpha kinase 2
chr1_-_113871665 0.27 ENST00000528414.5
ENST00000460620.5
ENST00000359785.10
ENST00000420377.6
ENST00000525799.1
ENST00000538253.5
protein tyrosine phosphatase non-receptor type 22
chr11_-_66958366 0.27 ENST00000651036.1
ENST00000652125.1
ENST00000531614.6
ENST00000524491.6
ENST00000529047.6
ENST00000393960.7
ENST00000393958.7
ENST00000528403.6
ENST00000651854.1
pyruvate carboxylase
chr6_+_110874775 0.27 ENST00000675380.1
ENST00000368882.8
ENST00000368877.9
ENST00000368885.8
ENST00000672937.2
adenosylmethionine decarboxylase 1
chr1_-_168543990 0.27 ENST00000367819.3
X-C motif chemokine ligand 2
chr6_+_31575557 0.27 ENST00000449264.3
tumor necrosis factor
chr17_+_7336502 0.27 ENST00000158762.8
ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
chr16_-_375205 0.26 ENST00000448854.1
post-glycosylphosphatidylinositol attachment to proteins 6
chr15_-_89211803 0.26 ENST00000563254.1
retinaldehyde binding protein 1
chr1_+_109910892 0.26 ENST00000369802.7
ENST00000420111.6
colony stimulating factor 1
chr2_+_238426920 0.26 ENST00000264607.9
ankyrin repeat and SOCS box containing 1
chrX_-_49184789 0.26 ENST00000453382.5
ENST00000432913.5
prickle planar cell polarity protein 3
chr1_+_209686173 0.26 ENST00000615289.4
ENST00000367028.6
ENST00000261465.5
hydroxysteroid 11-beta dehydrogenase 1
chr16_-_67964044 0.26 ENST00000537830.6
solute carrier family 12 member 4
chr1_+_50103903 0.25 ENST00000371827.5
ELAV like RNA binding protein 4
chr3_+_141324208 0.25 ENST00000509842.5
zinc finger and BTB domain containing 38
chr1_-_85578345 0.25 ENST00000426972.8
dimethylarginine dimethylaminohydrolase 1
chr2_+_74530018 0.25 ENST00000437202.1
HtrA serine peptidase 2
chr10_+_25174796 0.25 ENST00000650135.1
G protein-coupled receptor 158
chr20_+_44714853 0.25 ENST00000372865.4
cellular communication network factor 5
chr5_-_159208066 0.25 ENST00000519865.5
ENST00000521606.6
ring finger protein 145
chr6_+_116370938 0.24 ENST00000644252.3
ENST00000646710.1
ENST00000359564.3
dermatan sulfate epimerase
chrX_-_71618455 0.24 ENST00000373691.4
ENST00000373693.4
C-X-C motif chemokine receptor 3
chr9_-_120877026 0.24 ENST00000436309.5
PHD finger protein 19
chr19_-_43780957 0.24 ENST00000648319.1
potassium calcium-activated channel subfamily N member 4
chr9_-_120876356 0.24 ENST00000456291.1
PHD finger protein 19
chr2_-_49154433 0.24 ENST00000454032.5
ENST00000304421.8
follicle stimulating hormone receptor
chr15_+_73684204 0.24 ENST00000537340.6
ENST00000318424.9
CD276 molecule
chr20_+_44714835 0.23 ENST00000372868.6
cellular communication network factor 5
chr10_+_122374685 0.23 ENST00000368990.7
ENST00000368989.6
ENST00000463663.6
pleckstrin homology domain containing A1
chr2_-_49154507 0.23 ENST00000406846.7
follicle stimulating hormone receptor
chr1_+_209768597 0.23 ENST00000487271.5
ENST00000477431.1
TRAF3 interacting protein 3
chr13_-_102401599 0.23 ENST00000376131.8
fibroblast growth factor 14
chr2_-_18560616 0.23 ENST00000381249.4
retinol dehydrogenase 14
chr1_-_94925759 0.23 ENST00000415017.1
ENST00000545882.5
calponin 3
chr11_-_31803620 0.22 ENST00000639006.1
paired box 6
chr22_-_45240859 0.22 ENST00000336156.10
KIAA0930
chrX_-_15854743 0.22 ENST00000450644.2
adaptor related protein complex 1 subunit sigma 2
chr2_+_26848199 0.22 ENST00000401478.5
dihydropyrimidinase like 5
chr6_+_31547560 0.22 ENST00000376148.9
ENST00000376145.8
NFKB inhibitor like 1
chr3_+_98531965 0.22 ENST00000284311.5
G protein-coupled receptor 15
chr4_-_10684749 0.22 ENST00000226951.11
cytokine dependent hematopoietic cell linker
chr1_+_156338619 0.22 ENST00000481479.5
ENST00000368252.5
ENST00000466306.5
ENST00000368251.1
TSSK6 activating cochaperone
chr4_-_54064586 0.21 ENST00000263921.8
cysteine rich hydrophobic domain 2
chr6_-_114343012 0.21 ENST00000312719.10
heparan sulfate-glucosamine 3-sulfotransferase 5
chr1_-_172444055 0.21 ENST00000344529.5
ENST00000367728.1
phosphatidylinositol glycan anchor biosynthesis class C
chr17_+_19378476 0.20 ENST00000395604.8
ENST00000482850.1
mitogen-activated protein kinase 7
chr17_+_47733228 0.20 ENST00000177694.2
T-box transcription factor 21
chr22_+_21642287 0.20 ENST00000248958.5
stromal cell derived factor 2 like 1
chr19_-_50365625 0.20 ENST00000598915.5
ENST00000253719.7
napsin A aspartic peptidase
chr1_+_209756149 0.20 ENST00000367026.7
TRAF3 interacting protein 3
chr16_+_88382950 0.19 ENST00000565624.3
zinc finger protein 469
chr17_+_42844573 0.19 ENST00000253799.8
ENST00000452774.2
amine oxidase copper containing 2
chr17_+_81977587 0.19 ENST00000306739.9
ENST00000581647.5
ENST00000580534.5
ENST00000579684.5
ASPSCR1 tether for SLC2A4, UBX domain containing
chr8_-_95269190 0.19 ENST00000286688.6
chromosome 8 open reading frame 37
chr3_+_50246888 0.19 ENST00000451956.1
G protein subunit alpha i2
chr11_+_71538025 0.18 ENST00000398534.4
keratin associated protein 5-8
chr1_-_206772484 0.18 ENST00000423557.1
interleukin 10
chr1_+_172659095 0.18 ENST00000367721.3
ENST00000340030.4
Fas ligand
chr8_+_30387064 0.18 ENST00000523115.5
ENST00000519647.5
RNA binding protein, mRNA processing factor
chr5_+_172959511 0.18 ENST00000519522.1
ribosomal protein L26 like 1
chr1_-_1779976 0.18 ENST00000378625.5
NAD kinase
chr1_+_156338455 0.18 ENST00000368253.6
ENST00000470342.5
ENST00000368254.6
TSSK6 activating cochaperone
chr2_-_2324323 0.18 ENST00000648339.1
ENST00000647694.1
myelin transcription factor 1 like
chr11_+_71548420 0.18 ENST00000528743.4
keratin associated protein 5-9
chr15_+_49423233 0.18 ENST00000560270.1
ENST00000267843.9
ENST00000560979.1
fibroblast growth factor 7
chr14_+_22883220 0.18 ENST00000536884.1
ENST00000267396.9
RRAD and GEM like GTPase 2
chr12_-_16606795 0.17 ENST00000447609.5
LIM domain only 3
chr17_+_81977539 0.17 ENST00000306729.11
ASPSCR1 tether for SLC2A4, UBX domain containing
chr1_+_181483510 0.17 ENST00000367573.7
calcium voltage-gated channel subunit alpha1 E
chr5_-_138543198 0.17 ENST00000507939.5
ENST00000572514.5
ENST00000499810.6
ENST00000360541.10
eukaryotic translation termination factor 1
chr12_+_123973197 0.17 ENST00000392404.7
ENST00000337815.9
ENST00000538932.6
ENST00000618862.2
ENST00000389727.8
zinc finger protein 664
novel protein
refilin A
chr17_+_19377721 0.17 ENST00000308406.9
ENST00000299612.11
mitogen-activated protein kinase 7
chr16_-_11915878 0.17 ENST00000439887.6
ENST00000434724.7
G1 to S phase transition 1
chr12_+_93378625 0.17 ENST00000546925.1
nudix hydrolase 4
chr16_-_11915991 0.17 ENST00000420576.6
G1 to S phase transition 1
chr3_-_33645433 0.17 ENST00000635664.1
ENST00000485378.6
ENST00000313350.10
ENST00000487200.5
cytoplasmic linker associated protein 2
chr3_+_41199462 0.16 ENST00000647264.1
ENST00000645900.1
ENST00000646174.1
ENST00000643992.1
ENST00000647390.1
ENST00000642886.1
catenin beta 1
chr6_-_33289189 0.16 ENST00000374617.9
WD repeat domain 46
chr22_+_39901075 0.16 ENST00000344138.9
GRB2 related adaptor protein 2
chr16_-_68448491 0.16 ENST00000561749.1
ENST00000219334.10
sphingomyelin phosphodiesterase 3
chr10_+_24449426 0.16 ENST00000307544.10
KIAA1217
chr6_-_75202792 0.16 ENST00000416123.6
collagen type XII alpha 1 chain
chr14_+_21768482 0.16 ENST00000390428.3
T cell receptor alpha variable 6
chr7_-_29195186 0.16 ENST00000449801.5
ENST00000409850.5
carboxypeptidase vitellogenic like
chr19_-_15449920 0.15 ENST00000263381.12
ENST00000643092.1
ENST00000673675.1
WIZ zinc finger
chr2_+_167135901 0.15 ENST00000628543.2
xin actin binding repeat containing 2
chr1_-_153544997 0.15 ENST00000368715.5
S100 calcium binding protein A4
chr14_+_35292429 0.15 ENST00000555764.5
ENST00000556506.1
proteasome 20S subunit alpha 6
chr11_-_31803663 0.15 ENST00000638802.1
ENST00000638878.1
paired box 6
chr16_-_69384747 0.14 ENST00000566257.5
telomeric repeat binding factor 2
chr11_+_60971777 0.14 ENST00000542157.5
ENST00000433107.6
ENST00000352009.9
ENST00000452451.6
CD6 molecule
chr2_-_213151590 0.14 ENST00000374319.8
ENST00000457361.5
ENST00000451136.6
ENST00000434687.6
IKAROS family zinc finger 2
chr3_+_155083889 0.14 ENST00000680282.1
membrane metalloendopeptidase
chr16_+_85908988 0.14 ENST00000566369.1
interferon regulatory factor 8
chr3_+_155083523 0.14 ENST00000680057.1
membrane metalloendopeptidase
chr14_+_60509138 0.13 ENST00000327720.6
SIX homeobox 6
chr17_+_49210699 0.13 ENST00000225941.6
ABI family member 3

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 6.3 GO:1903974 positive regulation of odontogenesis of dentin-containing tooth(GO:0042488) mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) positive regulation of microglial cell migration(GO:1904141)
1.1 5.4 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.6 1.9 GO:0045362 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.6 1.8 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.5 1.5 GO:1901899 positive regulation of relaxation of cardiac muscle(GO:1901899)
0.3 1.8 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.3 4.4 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.3 1.0 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.3 0.8 GO:1904172 positive regulation of interleukin-1 alpha secretion(GO:0050717) regulation of bleb assembly(GO:1904170) positive regulation of bleb assembly(GO:1904172)
0.2 1.4 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.2 2.2 GO:1904996 positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
0.2 1.8 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.2 1.5 GO:0002051 osteoblast fate commitment(GO:0002051)
0.2 0.6 GO:2000866 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.2 0.5 GO:0001545 primary ovarian follicle growth(GO:0001545)
0.2 0.5 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.1 0.6 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.1 1.8 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.1 2.1 GO:0072619 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.1 0.6 GO:0048619 embryonic genitalia morphogenesis(GO:0030538) embryonic hindgut morphogenesis(GO:0048619)
0.1 0.3 GO:0060739 mesenchymal-epithelial cell signaling involved in prostate gland development(GO:0060739)
0.1 0.3 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.1 0.6 GO:0003383 apical constriction(GO:0003383)
0.1 0.4 GO:0030806 negative regulation of cyclic nucleotide catabolic process(GO:0030806) negative regulation of cAMP catabolic process(GO:0030821)
0.1 1.9 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.1 0.7 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.1 0.6 GO:0042483 negative regulation of odontogenesis(GO:0042483)
0.1 0.3 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.1 0.3 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.1 0.3 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.1 0.2 GO:0002728 negative regulation of natural killer cell cytokine production(GO:0002728)
0.1 0.2 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.1 0.5 GO:0044336 canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.1 0.2 GO:0060437 lung growth(GO:0060437)
0.1 0.2 GO:0061182 negative regulation of chondrocyte development(GO:0061182)
0.1 0.3 GO:1902523 negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433) positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.1 0.4 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.0 0.7 GO:0046541 saliva secretion(GO:0046541)
0.0 0.1 GO:0032208 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208) negative regulation of single strand break repair(GO:1903517) negative regulation of beta-galactosidase activity(GO:1903770) telomere single strand break repair(GO:1903823) negative regulation of telomere single strand break repair(GO:1903824)
0.0 0.5 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.0 0.2 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.0 0.1 GO:0044691 tooth eruption(GO:0044691)
0.0 0.2 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.7 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.1 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.0 0.1 GO:2001301 regulation of engulfment of apoptotic cell(GO:1901074) lipoxin biosynthetic process(GO:2001301) lipoxin A4 metabolic process(GO:2001302) lipoxin A4 biosynthetic process(GO:2001303)
0.0 0.3 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.0 0.2 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.1 GO:2000053 regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053)
0.0 0.1 GO:2000566 positive regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000566)
0.0 0.6 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0 0.3 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.0 0.1 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.0 0.1 GO:0071895 odontoblast differentiation(GO:0071895)
0.0 0.1 GO:0071898 regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899)
0.0 0.5 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.2 GO:1901908 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.0 0.1 GO:0071104 response to interleukin-9(GO:0071104)
0.0 0.1 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.0 0.5 GO:0003322 pancreatic A cell development(GO:0003322)
0.0 0.3 GO:0043129 surfactant homeostasis(GO:0043129)
0.0 0.3 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.0 0.1 GO:0048073 regulation of eye pigmentation(GO:0048073)
0.0 0.1 GO:0033076 alkaloid catabolic process(GO:0009822) isoquinoline alkaloid metabolic process(GO:0033076)
0.0 0.1 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
0.0 0.3 GO:0071492 cellular response to UV-A(GO:0071492)
0.0 0.9 GO:0048305 immunoglobulin secretion(GO:0048305)
0.0 0.1 GO:0002625 regulation of T cell antigen processing and presentation(GO:0002625)
0.0 0.3 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.1 GO:0032597 B cell receptor transport within lipid bilayer(GO:0032595) B cell receptor transport into membrane raft(GO:0032597) protein transport out of membrane raft(GO:0032599) chemokine receptor transport out of membrane raft(GO:0032600) negative regulation of transforming growth factor beta3 production(GO:0032913) chemokine receptor transport within lipid bilayer(GO:0033606)
0.0 0.2 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 0.1 GO:0098507 polynucleotide 5' dephosphorylation(GO:0098507)
0.0 0.2 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.0 0.1 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.0 0.1 GO:0032824 natural killer cell differentiation involved in immune response(GO:0002325) negative regulation of natural killer cell differentiation(GO:0032824) regulation of natural killer cell differentiation involved in immune response(GO:0032826) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827)
0.0 0.3 GO:0014894 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.2 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.1 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456) positive regulation of sperm motility(GO:1902093)
0.0 0.5 GO:0036315 cellular response to sterol(GO:0036315)
0.0 0.5 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.0 0.4 GO:0032354 response to follicle-stimulating hormone(GO:0032354)
0.0 0.4 GO:0034656 nucleobase-containing small molecule catabolic process(GO:0034656)
0.0 0.1 GO:0042109 lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.0 0.1 GO:0021780 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.0 0.3 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.4 GO:0032695 negative regulation of interleukin-12 production(GO:0032695)
0.0 0.4 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 0.3 GO:1900038 negative regulation of cellular response to hypoxia(GO:1900038)
0.0 0.1 GO:0050902 leukocyte adhesive activation(GO:0050902)
0.0 0.2 GO:0033327 Leydig cell differentiation(GO:0033327)
0.0 0.1 GO:0071394 cellular response to testosterone stimulus(GO:0071394)
0.0 0.1 GO:0070170 regulation of tooth mineralization(GO:0070170)
0.0 0.2 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0 0.3 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.1 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0 0.1 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.0 0.2 GO:0006449 regulation of translational termination(GO:0006449)
0.0 0.0 GO:1904562 phosphatidylinositol 5-phosphate metabolic process(GO:1904562)
0.0 0.0 GO:0098971 anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
0.0 0.0 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.0 0.2 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.1 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324)
0.0 0.1 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.0 0.1 GO:0033594 response to hydroxyisoflavone(GO:0033594)
0.0 0.1 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 0.3 GO:0030539 male genitalia development(GO:0030539)
0.0 0.2 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.2 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 0.6 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.0 0.1 GO:0002084 protein depalmitoylation(GO:0002084)
0.0 0.2 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.2 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0 0.2 GO:1903421 regulation of synaptic vesicle recycling(GO:1903421)
0.0 0.2 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.1 GO:0030886 negative regulation of myeloid dendritic cell activation(GO:0030886)
0.0 0.1 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.3 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.0 0.1 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.0 0.2 GO:0001973 adenosine receptor signaling pathway(GO:0001973)
0.0 0.3 GO:0098743 cell aggregation(GO:0098743)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 6.3 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.2 1.8 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.2 1.8 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.1 1.5 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.1 0.3 GO:0018444 translation release factor complex(GO:0018444)
0.1 1.4 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.3 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.0 0.8 GO:0032059 bleb(GO:0032059)
0.0 0.3 GO:0032279 asymmetric synapse(GO:0032279)
0.0 0.2 GO:0005595 collagen type XII trimer(GO:0005595)
0.0 0.4 GO:0070449 elongin complex(GO:0070449)
0.0 0.6 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.3 GO:0060091 kinocilium(GO:0060091)
0.0 0.4 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.3 GO:0097208 alveolar lamellar body(GO:0097208)
0.0 0.3 GO:0042587 glycogen granule(GO:0042587)
0.0 0.7 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.3 GO:0070938 contractile ring(GO:0070938)
0.0 0.1 GO:1990032 parallel fiber(GO:1990032)
0.0 0.1 GO:1990037 Lewy body core(GO:1990037)
0.0 0.5 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.3 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.1 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.0 0.2 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.2 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.1 GO:0070187 telosome(GO:0070187)
0.0 0.3 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.1 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.3 GO:0035098 ESC/E(Z) complex(GO:0035098)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 6.3 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.6 1.9 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.3 1.8 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.2 0.5 GO:0004963 follicle-stimulating hormone receptor activity(GO:0004963)
0.1 0.5 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797)
0.1 0.3 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.1 1.9 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 0.8 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 0.5 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1 0.4 GO:0008142 oxysterol binding(GO:0008142)
0.1 0.2 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.1 0.3 GO:0042835 BRE binding(GO:0042835)
0.1 0.3 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 0.2 GO:0070984 SET domain binding(GO:0070984)
0.1 0.3 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.0 0.2 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 1.4 GO:0031489 myosin V binding(GO:0031489)
0.0 2.5 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.2 GO:0052593 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.0 0.5 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 1.8 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.3 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 1.5 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.1 GO:0047977 hepoxilin-epoxide hydrolase activity(GO:0047977)
0.0 0.1 GO:0052810 1-phosphatidylinositol-5-kinase activity(GO:0052810)
0.0 0.1 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.0 0.3 GO:0045545 syndecan binding(GO:0045545)
0.0 0.4 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.3 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.4 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.3 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 2.0 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.2 GO:0052840 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.0 3.0 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.3 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 0.2 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.2 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 1.0 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 1.2 GO:0005109 frizzled binding(GO:0005109)
0.0 0.1 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.3 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.1 GO:0004651 polynucleotide 5'-phosphatase activity(GO:0004651)
0.0 0.1 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.0 4.8 GO:0070851 growth factor receptor binding(GO:0070851)
0.0 0.5 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.3 GO:0004075 biotin carboxylase activity(GO:0004075)
0.0 0.1 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.0 0.1 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.0 0.2 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.2 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 4.9 GO:0001047 core promoter binding(GO:0001047)
0.0 0.3 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.1 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.0 0.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.1 GO:0046848 hydroxyapatite binding(GO:0046848)
0.0 0.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.0 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923)
0.0 0.1 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.5 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.1 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.0 0.2 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.2 GO:0004568 chitinase activity(GO:0004568)
0.0 0.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 1.9 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 0.2 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 1.7 GO:0051117 ATPase binding(GO:0051117)
0.0 0.5 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.1 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.0 0.3 GO:0004707 MAP kinase activity(GO:0004707)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 8.1 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 6.2 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 4.8 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.8 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 2.1 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 1.4 PID IL23 PATHWAY IL23-mediated signaling events
0.0 1.0 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 1.3 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.5 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.5 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.6 ST GAQ PATHWAY G alpha q Pathway
0.0 0.4 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.5 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.4 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 5.1 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.1 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.4 ST GA12 PATHWAY G alpha 12 Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.8 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 5.3 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.1 1.7 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 1.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 1.6 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.8 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 1.6 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.5 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 1.9 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.3 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.4 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.5 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.4 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.9 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 0.5 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.5 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.3 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.1 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends