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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for RXRG

Z-value: 0.87

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Transcription factors associated with RXRG

Gene Symbol Gene ID Gene Info
ENSG00000143171.13 RXRG

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RXRGhg38_v1_chr1_-_165445088_165445140,
hg38_v1_chr1_-_165445220_165445355
0.009.8e-01Click!

Activity profile of RXRG motif

Sorted Z-values of RXRG motif

Network of associatons between targets according to the STRING database.

First level regulatory network of RXRG

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr14_-_35404650 1.11 ENST00000553342.1
ENST00000557140.5
ENST00000216797.10
NFKB inhibitor alpha
chr1_+_153778178 0.87 ENST00000532853.5
solute carrier family 27 member 3
chr19_-_1174227 0.85 ENST00000587024.5
ENST00000361757.8
strawberry notch homolog 2
chrX_+_49053554 0.80 ENST00000597275.5
coiled-coil domain containing 120
chr18_+_59899988 0.76 ENST00000316660.7
ENST00000269518.9
phorbol-12-myristate-13-acetate-induced protein 1
chr10_+_79706328 0.74 ENST00000342531.2
NUT family member 2B
chr11_-_76670737 0.70 ENST00000260061.9
ENST00000404995.5
leucine rich repeat containing 32
chr12_-_108857568 0.70 ENST00000326495.10
ENST00000551165.5
slingshot protein phosphatase 1
chr20_-_63831214 0.68 ENST00000302995.2
ENST00000245663.9
zinc finger and BTB domain containing 46
chr17_-_81870974 0.67 ENST00000541078.6
Rho GDP dissociation inhibitor alpha
chr19_-_7926106 0.60 ENST00000318978.6
cortexin 1
chrX_+_150363306 0.59 ENST00000370401.7
ENST00000432680.7
mastermind like domain containing 1
chrX_+_150363258 0.58 ENST00000683696.1
mastermind like domain containing 1
chr5_-_176629943 0.58 ENST00000510387.5
ENST00000506696.1
synuclein beta
chr4_+_127965429 0.55 ENST00000513371.1
ENST00000611882.1
abhydrolase domain containing 18
chr17_-_75878542 0.55 ENST00000254816.6
tripartite motif containing 47
chr5_-_136193143 0.54 ENST00000607574.2
small integral membrane protein 32
chr15_+_40929338 0.53 ENST00000249749.7
delta like canonical Notch ligand 4
chr11_-_119364166 0.53 ENST00000525735.1
ubiquitin specific peptidase 2
chr20_+_64063481 0.52 ENST00000415602.5
transcription elongation factor A2
chr15_+_67166019 0.52 ENST00000537194.6
SMAD family member 3
chr1_-_32870775 0.52 ENST00000649537.2
ENST00000373471.9
fibronectin type III domain containing 5
chr11_-_30586272 0.50 ENST00000448418.6
metallophosphoesterase domain containing 2
chr17_-_81871314 0.50 ENST00000581876.5
ENST00000584461.5
ENST00000269321.12
ENST00000583868.5
ENST00000400721.8
Rho GDP dissociation inhibitor alpha
chr2_-_27380715 0.48 ENST00000323703.11
ENST00000436006.1
zinc finger protein 513
chr11_+_67119245 0.47 ENST00000529006.7
ENST00000398645.6
lysine demethylase 2A
chr9_-_114682172 0.46 ENST00000436752.3
testis expressed 48
chr9_-_114682061 0.46 ENST00000612244.5
testis expressed 48
chr1_-_153946652 0.46 ENST00000361217.9
DENN domain containing 4B
chr11_-_30586866 0.46 ENST00000528686.2
metallophosphoesterase domain containing 2
chr11_+_65615755 0.45 ENST00000355703.4
pecanex 3
chr11_-_76206407 0.45 ENST00000621122.1
ENST00000322563.8
Wnt family member 11
chr6_+_35259703 0.44 ENST00000373953.8
ENST00000339411.5
zinc finger protein 76
chr17_+_7281711 0.43 ENST00000317370.13
ENST00000571308.5
solute carrier family 2 member 4
chr11_+_65638085 0.42 ENST00000534313.6
ENST00000533361.1
ENST00000526137.1
signal-induced proliferation-associated 1
chr7_+_2631978 0.42 ENST00000258796.12
tweety family member 3
chr19_+_3506355 0.41 ENST00000652521.1
fizzy and cell division cycle 20 related 1
chr7_+_100720463 0.40 ENST00000252723.3
erythropoietin
chr17_+_82371762 0.40 ENST00000313135.5
urotensin 2 receptor
chr11_-_59668981 0.40 ENST00000300146.10
PAT1 homolog 1, processing body mRNA decay factor
chr13_+_95552701 0.40 ENST00000299339.3
claudin 10
chr5_+_171419635 0.40 ENST00000274625.6
fibroblast growth factor 18
chr17_-_75848641 0.40 ENST00000586257.5
WW domain binding protein 2
chr19_+_7522605 0.40 ENST00000264079.11
mucolipin TRP cation channel 1
chr19_+_44748673 0.39 ENST00000164227.10
BCL3 transcription coactivator
chr11_+_450255 0.39 ENST00000308020.6
phosphatidylserine synthase 2
chr11_-_65663083 0.38 ENST00000308639.13
RELA proto-oncogene, NF-kB subunit
chr2_-_207166818 0.38 ENST00000423015.5
Kruppel like factor 7
chr17_-_45490696 0.38 ENST00000430334.8
ENST00000584420.1
ENST00000589780.5
pleckstrin homology and RUN domain containing M1
chr12_+_131929219 0.38 ENST00000322060.9
pseudouridine synthase 1
chr11_+_65639860 0.38 ENST00000527525.5
signal-induced proliferation-associated 1
chr2_-_174764407 0.37 ENST00000409219.5
ENST00000409542.5
cholinergic receptor nicotinic alpha 1 subunit
chr14_-_103521342 0.37 ENST00000553610.5
creatine kinase B
chr19_-_6424802 0.37 ENST00000600480.2
KH-type splicing regulatory protein
chr9_-_16728165 0.37 ENST00000603713.5
ENST00000603313.5
basonuclin 2
chr19_+_17075767 0.36 ENST00000682292.1
ENST00000595618.5
ENST00000594824.5
myosin IXB
chr3_+_122680802 0.36 ENST00000474629.7
poly(ADP-ribose) polymerase family member 14
chr22_-_19524400 0.36 ENST00000618236.2
claudin 5
chr1_-_154974361 0.35 ENST00000368453.8
ENST00000368450.5
SHC adaptor protein 1
chr14_-_74426102 0.35 ENST00000554953.1
ENST00000331628.8
synapse differentiation inducing 1 like
chr7_+_44606619 0.35 ENST00000222673.6
ENST00000444676.5
ENST00000631326.2
oxoglutarate dehydrogenase
chr2_+_27078598 0.35 ENST00000380320.9
elastin microfibril interfacer 1
chr11_-_65662931 0.34 ENST00000615805.4
ENST00000612991.4
RELA proto-oncogene, NF-kB subunit
chr1_-_153549120 0.34 ENST00000368712.1
S100 calcium binding protein A3
chr19_-_49929525 0.34 ENST00000596437.5
ENST00000341114.7
ENST00000595948.5
nucleoporin 62
interleukin 4 induced 1
chr1_+_1308714 0.33 ENST00000467712.1
pseudouridine synthase like 1
chr19_+_42284483 0.33 ENST00000575354.6
capicua transcriptional repressor
chr16_-_29923237 0.33 ENST00000568995.1
ENST00000566413.1
potassium channel tetramerization domain containing 13
chr7_+_2632029 0.33 ENST00000407643.5
tweety family member 3
chr20_+_44910045 0.33 ENST00000255136.8
ENST00000217073.7
poly(A) binding protein cytoplasmic 1 like
chr19_-_49155384 0.33 ENST00000252825.9
histidine rich calcium binding protein
chr15_+_73683938 0.33 ENST00000567189.5
CD276 molecule
chr9_+_129835442 0.33 ENST00000372429.8
ENST00000315480.9
ENST00000358355.5
ubiquitin specific peptidase 20
chr19_-_1021114 0.32 ENST00000333175.9
ENST00000356663.8
transmembrane protein 259
chr11_-_62612725 0.32 ENST00000419857.1
ENST00000394773.7
EMAP like 3
chr1_-_6485433 0.31 ENST00000535355.6
pleckstrin homology and RhoGEF domain containing G5
chr5_-_173235194 0.31 ENST00000329198.5
ENST00000521848.1
NK2 homeobox 5
chr19_-_10334723 0.31 ENST00000592945.1
intercellular adhesion molecule 3
chr9_+_37650947 0.30 ENST00000377765.8
FERM and PDZ domain containing 1
chr2_+_96537254 0.30 ENST00000454558.2
AT-rich interaction domain 5A
chr19_+_676385 0.30 ENST00000166139.9
follistatin like 3
chr18_+_46174055 0.30 ENST00000615553.1
chromosome 18 open reading frame 25
chr21_+_42219111 0.30 ENST00000450121.5
ENST00000361802.6
ATP binding cassette subfamily G member 1
chr1_+_77779763 0.30 ENST00000646892.1
ENST00000645526.1
mitoguardin 1
chr17_+_42659264 0.30 ENST00000251412.8
tubulin gamma 2
chr11_-_65614195 0.30 ENST00000309100.8
ENST00000529839.1
ENST00000526293.1
mitogen-activated protein kinase kinase kinase 11
chr7_+_44606563 0.29 ENST00000439616.6
oxoglutarate dehydrogenase
chrX_+_154437147 0.29 ENST00000447750.7
GDP dissociation inhibitor 1
chr14_+_24115299 0.29 ENST00000559354.5
ENST00000560459.5
ENST00000559593.5
ENST00000396941.8
ENST00000396936.5
DDB1 and CUL4 associated factor 11
chr2_-_219245465 0.29 ENST00000392089.6
galactosidase beta 1 like
chr12_-_54588516 0.29 ENST00000547431.5
protein phosphatase 1 regulatory inhibitor subunit 1A
chr17_+_7888783 0.29 ENST00000330494.12
ENST00000358181.8
chromodomain helicase DNA binding protein 3
chr19_+_16661121 0.29 ENST00000187762.7
ENST00000599479.1
transmembrane protein 38A
chr7_-_100119840 0.28 ENST00000437822.6
TATA-box binding protein associated factor 6
chr5_+_174045673 0.28 ENST00000303177.8
ENST00000519867.5
neuronal vesicle trafficking associated 2
chr1_-_6701795 0.28 ENST00000426784.1
ENST00000377577.10
ENST00000294401.11
DnaJ heat shock protein family (Hsp40) member C11
chr17_+_34285734 0.28 ENST00000305869.4
C-C motif chemokine ligand 11
chr19_+_49851173 0.28 ENST00000599732.5
PTOV1 extended AT-hook containing adaptor protein
chr9_-_128771909 0.28 ENST00000291900.7
ENST00000414921.5
zyg-11 related cell cycle regulator
chr2_+_233195433 0.28 ENST00000417661.1
inositol polyphosphate-5-phosphatase D
chr9_+_128566741 0.27 ENST00000630866.1
spectrin alpha, non-erythrocytic 1
chr21_+_38805895 0.27 ENST00000667466.1
ENST00000360938.8
ENST00000432278.5
ETS proto-oncogene 2, transcription factor
chr14_-_37595224 0.27 ENST00000250448.5
forkhead box A1
chr8_+_144095054 0.27 ENST00000318911.5
cytochrome c1
chr1_-_37808168 0.26 ENST00000373044.3
yrdC N6-threonylcarbamoyltransferase domain containing
chr19_-_49929396 0.26 ENST00000596680.5
ENST00000594673.5
ENST00000597029.5
nucleoporin 62
chr19_-_5784599 0.26 ENST00000390672.2
ENST00000419421.3
proline rich 22
chr19_+_49851136 0.26 ENST00000391842.5
PTOV1 extended AT-hook containing adaptor protein
chr19_+_49851205 0.26 ENST00000601675.5
PTOV1 extended AT-hook containing adaptor protein
chr11_-_1757452 0.26 ENST00000427721.3
novel protein
chr11_-_65662780 0.26 ENST00000534283.1
ENST00000527749.5
ENST00000533187.5
ENST00000525693.5
ENST00000534558.5
ENST00000532879.5
ENST00000406246.8
ENST00000532999.5
RELA proto-oncogene, NF-kB subunit
chr9_-_107489754 0.26 ENST00000610832.1
ENST00000374672.5
Kruppel like factor 4
chr5_+_129904458 0.25 ENST00000305031.5
chondroitin sulfate synthase 3
chr5_+_134526100 0.25 ENST00000395003.5
jade family PHD finger 2
chr1_-_153549238 0.25 ENST00000368713.8
S100 calcium binding protein A3
chr19_+_2328663 0.25 ENST00000614794.4
ENST00000613503.5
ENST00000610743.4
ENST00000618220.4
signal peptide peptidase like 2B
chr10_+_26697653 0.25 ENST00000376215.10
decaprenyl diphosphate synthase subunit 1
chr19_+_38899680 0.25 ENST00000576510.5
ENST00000392079.7
NFKB inhibitor beta
chr6_+_43770707 0.25 ENST00000324450.11
ENST00000417285.7
ENST00000413642.8
ENST00000372055.9
ENST00000482630.7
ENST00000425836.7
ENST00000372064.9
ENST00000372077.8
ENST00000519767.5
vascular endothelial growth factor A
chr3_-_48635426 0.24 ENST00000455886.6
ENST00000431739.5
ENST00000426599.1
ENST00000383733.7
ENST00000395550.7
ENST00000420764.6
ENST00000337000.12
solute carrier family 26 member 6
chr19_+_35138993 0.24 ENST00000612146.4
ENST00000589209.5
FXYD domain containing ion transport regulator 1
chr17_-_78782257 0.24 ENST00000591455.5
ENST00000446868.7
ENST00000361101.8
ENST00000589296.5
cytohesin 1
chr22_-_31662180 0.24 ENST00000435900.5
phosphatidylserine decarboxylase
chr17_+_44846318 0.24 ENST00000591513.5
HIG1 hypoxia inducible domain family member 1B
chr7_-_149497664 0.24 ENST00000461958.2
zinc finger protein 746
chr7_+_30028644 0.24 ENST00000440706.3
pleckstrin homology domain containing A8
chr9_-_127755243 0.23 ENST00000629203.2
ENST00000420366.5
SH2 domain containing 3C
chr11_+_66268575 0.23 ENST00000527397.1
ENST00000311481.11
RAB1B, member RAS oncogene family
chr19_-_38831659 0.23 ENST00000601094.5
ENST00000595567.1
ENST00000602115.1
ENST00000601778.5
ENST00000597205.1
ENST00000595470.1
ENST00000221418.9
enoyl-CoA hydratase 1
chrX_-_48957871 0.23 ENST00000610466.4
OTU deubiquitinase 5
chr8_+_27774566 0.23 ENST00000519637.1
establishment of sister chromatid cohesion N-acetyltransferase 2
chr14_+_54509885 0.23 ENST00000557317.1
ENST00000216420.12
cell growth regulator with ring finger domain 1
chr12_+_48978313 0.23 ENST00000293549.4
Wnt family member 1
chr17_+_60149966 0.23 ENST00000300900.9
carbonic anhydrase 4
chr7_+_112450451 0.23 ENST00000429071.5
ENST00000403825.8
ENST00000675268.1
interferon related developmental regulator 1
novel protein
chr1_-_150876697 0.23 ENST00000515192.5
aryl hydrocarbon receptor nuclear translocator
chr19_+_7637099 0.23 ENST00000595950.5
ENST00000221283.10
ENST00000441779.6
ENST00000414284.6
syntaxin binding protein 2
chrX_-_47650488 0.23 ENST00000247161.7
ENST00000376983.8
ENST00000343894.8
ETS transcription factor ELK1
chr19_+_49850687 0.23 ENST00000594151.5
ENST00000600603.5
ENST00000601638.5
PTOV1 extended AT-hook containing adaptor protein
chr1_-_159924529 0.23 ENST00000320307.8
transgelin 2
chr14_+_36657560 0.23 ENST00000402703.6
paired box 9
chr19_+_35139440 0.23 ENST00000455515.6
FXYD domain containing ion transport regulator 1
chrX_-_2500555 0.23 ENST00000381218.8
zinc finger BED-type containing 1
chr3_-_46693641 0.23 ENST00000415953.5
ALS2 C-terminal like
chr5_+_132257670 0.22 ENST00000253754.8
ENST00000379018.7
PDZ and LIM domain 4
chr16_+_29806078 0.22 ENST00000545521.5
MYC associated zinc finger protein
chr3_+_47380995 0.22 ENST00000456221.5
ENST00000265562.5
protein tyrosine phosphatase non-receptor type 23
chr20_-_23986795 0.22 ENST00000286890.8
ENST00000278765.8
gamma-glutamyltransferase light chain 1
chr6_+_125790922 0.22 ENST00000453302.5
ENST00000417494.5
ENST00000392477.7
ENST00000229634.13
nuclear receptor coactivator 7
chr14_+_75278820 0.22 ENST00000554617.1
ENST00000554212.5
ENST00000535987.5
ENST00000303562.9
ENST00000555242.1
Fos proto-oncogene, AP-1 transcription factor subunit
chr19_-_58558871 0.22 ENST00000595957.5
ubiquitin conjugating enzyme E2 M
chr16_+_29807536 0.22 ENST00000567444.5
MYC associated zinc finger protein
chr1_-_44355061 0.22 ENST00000649995.1
ENST00000457571.1
ENST00000372257.7
ENST00000452396.5
ERI1 exoribonuclease family member 3
chr20_-_57710539 0.22 ENST00000395816.7
ENST00000347215.8
prostate transmembrane protein, androgen induced 1
chr19_+_35139724 0.22 ENST00000588715.5
ENST00000588607.5
FXYD domain containing ion transport regulator 1
chr6_+_43770202 0.22 ENST00000372067.8
ENST00000672860.2
vascular endothelial growth factor A
chr19_-_49155130 0.22 ENST00000595625.1
histidine rich calcium binding protein
chr11_+_67415670 0.21 ENST00000531040.5
ENST00000307823.7
carnosine synthase 1
chr9_-_136439796 0.21 ENST00000676019.1
ENST00000371712.4
inositol polyphosphate-5-phosphatase E
chr21_-_31731947 0.21 ENST00000434667.3
SR-related CTD associated factor 4
chr19_-_49929454 0.21 ENST00000597723.5
ENST00000599788.1
ENST00000352066.8
ENST00000596217.1
ENST00000593652.5
ENST00000599567.5
ENST00000600935.1
ENST00000596011.1
ENST00000596022.5
ENST00000597295.5
nucleoporin 62
interleukin 4 induced 1
chr5_+_77210881 0.21 ENST00000340978.7
ENST00000346042.7
ENST00000342343.8
ENST00000333194.8
phosphodiesterase 8B
chr16_+_21663968 0.21 ENST00000646100.2
otoancorin
chr22_+_41833079 0.21 ENST00000612482.4
ENST00000361204.9
sterol regulatory element binding transcription factor 2
chr11_-_1763894 0.21 ENST00000637915.1
ENST00000637815.2
ENST00000236671.7
ENST00000636571.1
ENST00000438213.6
ENST00000637387.1
ENST00000636843.1
ENST00000636397.1
ENST00000636615.1
cathepsin D
novel protein
chr9_-_136203183 0.21 ENST00000371746.9
LIM homeobox 3
chr6_-_4079100 0.21 ENST00000492651.5
ENST00000498677.5
ENST00000274673.8
family with sequence similarity 217 member A
chr19_+_55675191 0.21 ENST00000270460.11
ENST00000085079.11
epsin 1
chr17_-_41060109 0.21 ENST00000391418.3
keratin associated protein 2-3
chr6_+_89081787 0.21 ENST00000354922.3
proline rich nuclear receptor coactivator 1
chr8_-_144326908 0.20 ENST00000332324.5
diacylglycerol O-acyltransferase 1
chr11_-_30586344 0.20 ENST00000358117.10
metallophosphoesterase domain containing 2
chr12_+_53425070 0.20 ENST00000550839.1
anti-Mullerian hormone receptor type 2
chr1_+_9588860 0.20 ENST00000340381.11
ENST00000340305.9
transmembrane protein 201
chr6_+_42050876 0.20 ENST00000465926.5
ENST00000482432.1
TATA-box binding protein associated factor 8
chr2_+_229922482 0.20 ENST00000283946.8
ENST00000409992.1
F-box protein 36
chr19_+_38899946 0.20 ENST00000572515.5
ENST00000313582.6
ENST00000575359.5
NFKB inhibitor beta
chrX_-_48957548 0.20 ENST00000376488.8
ENST00000396743.7
ENST00000156084.8
OTU deubiquitinase 5
chr17_-_2711633 0.20 ENST00000435359.5
clustered mitochondria homolog
chr3_+_14947568 0.20 ENST00000413118.5
ENST00000425241.5
nuclear receptor subfamily 2 group C member 2
chr12_-_55829580 0.20 ENST00000678005.2
ENST00000546957.2
DnaJ heat shock protein family (Hsp40) member C14
chrX_-_71254106 0.20 ENST00000373984.7
ENST00000314425.9
ENST00000373982.5
zinc finger MYM-type containing 3
chr12_+_53985783 0.20 ENST00000513209.1
novel protein, readthrough between HOXC10 and HOXC5
chr6_+_18155399 0.20 ENST00000650836.2
ENST00000449850.2
ENST00000297792.9
lysine demethylase 1B
chr20_-_57710001 0.19 ENST00000341744.8
prostate transmembrane protein, androgen induced 1
chr19_+_52369911 0.19 ENST00000424032.6
ENST00000422689.3
ENST00000600321.5
ENST00000344085.9
ENST00000597976.5
zinc finger protein 880
chr12_-_121296685 0.19 ENST00000412367.6
ENST00000404169.8
ENST00000402834.8
calcium/calmodulin dependent protein kinase kinase 2
chr17_-_2711736 0.19 ENST00000651024.2
ENST00000576885.5
ENST00000574426.7
clustered mitochondria homolog
chr10_+_132537814 0.19 ENST00000368593.7
inositol polyphosphate-5-phosphatase A
chr20_+_64063105 0.19 ENST00000395053.7
ENST00000343484.10
ENST00000339217.8
transcription elongation factor A2
chr19_-_14117729 0.19 ENST00000590853.5
ENST00000308677.9
protein kinase cAMP-activated catalytic subunit alpha
chr12_+_12725897 0.19 ENST00000326765.10
apolipoprotein L domain containing 1
chr12_-_51391398 0.19 ENST00000356317.8
ENST00000603188.5
ENST00000604847.5
ENST00000604506.5
polypeptide N-acetylgalactosaminyltransferase 6
chrX_-_318814 0.19 ENST00000326153.9
GTP binding protein 6 (putative)
chr2_-_174764436 0.19 ENST00000409323.1
ENST00000261007.9
ENST00000348749.9
ENST00000672640.1
cholinergic receptor nicotinic alpha 1 subunit
chr22_-_29388530 0.18 ENST00000357586.7
ENST00000432560.6
ENST00000405198.6
ENST00000317368.11
adaptor related protein complex 1 subunit beta 1
chr22_-_41286168 0.18 ENST00000356244.8
Ran GTPase activating protein 1
chr22_-_41285868 0.18 ENST00000422838.1
ENST00000405486.5
Ran GTPase activating protein 1
chr4_+_2059286 0.18 ENST00000423729.3
N-acetyltransferase 8 like
chr11_-_31805795 0.18 ENST00000640766.1
paired box 6

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0006117 acetaldehyde metabolic process(GO:0006117)
0.2 0.7 GO:0070902 mitochondrial tRNA pseudouridine synthesis(GO:0070902)
0.2 0.7 GO:1904717 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.2 0.8 GO:1903438 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.2 0.8 GO:0042631 cellular response to water deprivation(GO:0042631)
0.2 0.8 GO:0061034 olfactory bulb mitral cell layer development(GO:0061034)
0.2 0.5 GO:1901899 positive regulation of relaxation of cardiac muscle(GO:1901899)
0.2 1.1 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.2 0.5 GO:1903570 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.2 0.5 GO:0060031 mediolateral intercalation(GO:0060031) planar cell polarity pathway involved in gastrula mediolateral intercalation(GO:0060775)
0.1 0.8 GO:0071105 response to interleukin-11(GO:0071105)
0.1 0.4 GO:0038162 erythropoietin-mediated signaling pathway(GO:0038162)
0.1 0.4 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.1 0.4 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.1 0.5 GO:0003342 proepicardium development(GO:0003342) septum transversum development(GO:0003343)
0.1 0.7 GO:0010731 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.1 0.3 GO:1903028 positive regulation of opsonization(GO:1903028)
0.1 0.3 GO:0009720 detection of hormone stimulus(GO:0009720)
0.1 0.4 GO:1904117 response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117)
0.1 0.3 GO:0060738 epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738)
0.1 0.5 GO:0061074 regulation of neural retina development(GO:0061074) negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.1 0.3 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 0.5 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.1 0.3 GO:0014740 negative regulation of muscle hyperplasia(GO:0014740)
0.1 0.8 GO:0032482 Rab protein signal transduction(GO:0032482)
0.1 0.3 GO:0061183 dermatome development(GO:0061054) regulation of dermatome development(GO:0061183)
0.1 0.2 GO:0042938 dipeptide transport(GO:0042938)
0.1 0.2 GO:0007518 myoblast fate determination(GO:0007518)
0.1 1.0 GO:0030853 negative regulation of granulocyte differentiation(GO:0030853)
0.1 0.2 GO:1901535 regulation of DNA demethylation(GO:1901535) negative regulation of DNA demethylation(GO:1901536)
0.1 0.2 GO:0035498 carnosine metabolic process(GO:0035498)
0.1 0.3 GO:0035962 response to interleukin-13(GO:0035962)
0.1 0.2 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.1 0.2 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.1 0.3 GO:1903296 regulation of glutamate secretion, neurotransmission(GO:1903294) positive regulation of glutamate secretion, neurotransmission(GO:1903296)
0.1 0.4 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.1 0.6 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.1 0.5 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.1 0.4 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
0.1 0.4 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.1 0.2 GO:0031446 regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448)
0.1 0.3 GO:0034124 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
0.1 0.4 GO:2000546 positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.1 0.3 GO:0034421 post-translational protein acetylation(GO:0034421)
0.1 0.2 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.1 0.3 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.1 0.5 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.1 0.2 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.0 0.3 GO:1902962 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.0 0.8 GO:0010917 negative regulation of mitochondrial membrane potential(GO:0010917)
0.0 0.2 GO:2000325 regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
0.0 0.1 GO:1903538 meiotic spindle elongation(GO:0051232) meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
0.0 0.3 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
0.0 0.1 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0 0.2 GO:0000961 negative regulation of mitochondrial RNA catabolic process(GO:0000961)
0.0 0.7 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.1 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.0 0.1 GO:0006021 inositol biosynthetic process(GO:0006021)
0.0 0.2 GO:1902613 regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
0.0 0.5 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.0 0.2 GO:1902463 protein localization to cell leading edge(GO:1902463)
0.0 0.2 GO:1903609 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.0 0.3 GO:0001712 ectoderm formation(GO:0001705) ectodermal cell fate commitment(GO:0001712)
0.0 0.2 GO:2000077 UDP-glucose catabolic process(GO:0006258) negative regulation of type B pancreatic cell development(GO:2000077)
0.0 0.4 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.0 0.1 GO:0071529 cementum mineralization(GO:0071529)
0.0 0.3 GO:0046886 positive regulation of hormone biosynthetic process(GO:0046886)
0.0 0.3 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 0.1 GO:1904383 response to sodium phosphate(GO:1904383)
0.0 0.0 GO:0048294 negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.0 0.3 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.2 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.2 GO:1904016 response to Thyroglobulin triiodothyronine(GO:1904016)
0.0 0.1 GO:0075509 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.0 0.1 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
0.0 0.1 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.0 0.3 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.2 GO:0015692 lead ion transport(GO:0015692)
0.0 0.1 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.0 0.3 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0 0.1 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.0 0.5 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.0 0.5 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.1 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.0 0.3 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 0.1 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.0 0.2 GO:0015862 uridine transport(GO:0015862)
0.0 0.3 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.0 0.3 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.0 0.2 GO:0032485 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.0 0.2 GO:1904100 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.0 0.1 GO:0001808 negative regulation of type IV hypersensitivity(GO:0001808)
0.0 0.4 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.2 GO:0031642 negative regulation of myelination(GO:0031642)
0.0 0.2 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324)
0.0 0.4 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.1 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
0.0 0.1 GO:0061668 mitochondrial ribosome assembly(GO:0061668)
0.0 0.2 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.1 GO:0044725 chromatin reprogramming in the zygote(GO:0044725)
0.0 0.3 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.1 GO:1901143 insulin catabolic process(GO:1901143)
0.0 0.1 GO:0036114 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.0 0.2 GO:0031086 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.1 GO:0086047 membrane depolarization during Purkinje myocyte cell action potential(GO:0086047)
0.0 0.3 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.5 GO:0090344 negative regulation of cell aging(GO:0090344)
0.0 0.2 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 0.1 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.0 0.3 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.1 GO:0035627 ceramide transport(GO:0035627)
0.0 0.2 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.0 0.1 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0 0.5 GO:0046838 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.0 0.0 GO:0061551 trigeminal ganglion development(GO:0061551)
0.0 0.9 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.0 0.3 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.0 0.1 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.0 0.3 GO:0035385 Roundabout signaling pathway(GO:0035385)
0.0 0.1 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.0 0.1 GO:0042360 vitamin E metabolic process(GO:0042360)
0.0 0.1 GO:1903182 regulation of SUMO transferase activity(GO:1903182) positive regulation of SUMO transferase activity(GO:1903755)
0.0 0.2 GO:0071394 cellular response to testosterone stimulus(GO:0071394)
0.0 0.3 GO:0008212 mineralocorticoid biosynthetic process(GO:0006705) mineralocorticoid metabolic process(GO:0008212)
0.0 0.3 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.2 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.0 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.0 0.6 GO:0043586 tongue development(GO:0043586)
0.0 0.1 GO:1901073 N-acetylglucosamine biosynthetic process(GO:0006045) glucosamine-containing compound biosynthetic process(GO:1901073)
0.0 0.2 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.0 0.1 GO:0034239 macrophage fusion(GO:0034238) regulation of macrophage fusion(GO:0034239) positive regulation of macrophage fusion(GO:0034241)
0.0 0.3 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.1 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 0.1 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.7 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.1 GO:0045588 positive regulation of gamma-delta T cell differentiation(GO:0045588)
0.0 0.1 GO:0042090 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.0 0.1 GO:0045905 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 0.2 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.1 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.0 0.1 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.4 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.3 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.1 GO:0090166 Golgi disassembly(GO:0090166)
0.0 0.3 GO:1904294 positive regulation of ERAD pathway(GO:1904294)
0.0 0.1 GO:0018094 protein polyglycylation(GO:0018094)
0.0 0.2 GO:0036155 acylglycerol acyl-chain remodeling(GO:0036155)
0.0 0.1 GO:0007207 phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.0 0.1 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0 0.1 GO:0045023 G0 to G1 transition(GO:0045023)
0.0 0.5 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.2 GO:0007097 nuclear migration(GO:0007097)
0.0 0.1 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0 0.1 GO:0090170 regulation of Golgi inheritance(GO:0090170)
0.0 0.3 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 0.1 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.0 0.1 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.0 0.2 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.0 0.1 GO:0000023 maltose metabolic process(GO:0000023)
0.0 0.1 GO:0019087 renal water transport(GO:0003097) transformation of host cell by virus(GO:0019087) renal water absorption(GO:0070295)
0.0 0.0 GO:0003147 neural crest cell migration involved in heart formation(GO:0003147) cell migration involved in heart formation(GO:0060974) anterior neural tube closure(GO:0061713)
0.0 0.0 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.0 0.1 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
0.0 0.2 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.0 0.0 GO:0006083 acetate metabolic process(GO:0006083)
0.0 0.4 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.0 GO:1902617 response to fluoride(GO:1902617)
0.0 0.2 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0 0.2 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.1 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.0 0.1 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.0 0.1 GO:0035524 proline transmembrane transport(GO:0035524)
0.0 0.0 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.0 0.1 GO:0090308 regulation of methylation-dependent chromatin silencing(GO:0090308)
0.0 0.1 GO:0032815 negative regulation of natural killer cell activation(GO:0032815)
0.0 0.4 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0 0.7 GO:0032784 regulation of DNA-templated transcription, elongation(GO:0032784)
0.0 0.2 GO:0003322 pancreatic A cell development(GO:0003322)
0.0 0.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.4 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.2 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.3 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.1 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0035525 NF-kappaB p50/p65 complex(GO:0035525)
0.2 1.5 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 0.4 GO:1990723 cytoplasmic periphery of the nuclear pore complex(GO:1990723)
0.1 0.4 GO:0070435 Shc-EGFR complex(GO:0070435)
0.1 0.4 GO:0031523 Myb complex(GO:0031523)
0.1 0.3 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.1 1.0 GO:0005642 annulate lamellae(GO:0005642)
0.1 0.6 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.1 0.5 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 0.2 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.5 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.3 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.2 GO:1990032 parallel fiber(GO:1990032)
0.0 0.3 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.0 0.2 GO:1990742 microvesicle(GO:1990742)
0.0 1.2 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.5 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.2 GO:0072534 perineuronal net(GO:0072534)
0.0 0.2 GO:0036398 TCR signalosome(GO:0036398)
0.0 0.2 GO:0070826 paraferritin complex(GO:0070826)
0.0 0.7 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.1 GO:0035517 PR-DUB complex(GO:0035517)
0.0 0.2 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.2 GO:0035976 AP1 complex(GO:0035976)
0.0 0.8 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.1 GO:0045160 myosin I complex(GO:0045160)
0.0 0.2 GO:0044194 cytolytic granule(GO:0044194)
0.0 0.5 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.1 GO:1990356 sumoylated E2 ligase complex(GO:1990356)
0.0 0.2 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.2 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.3 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.3 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.2 GO:0016600 flotillin complex(GO:0016600)
0.0 0.1 GO:0060987 lipid tube(GO:0060987)
0.0 0.5 GO:0000178 exosome (RNase complex)(GO:0000178)
0.0 0.0 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.3 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.4 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.4 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.1 GO:0097443 sorting endosome(GO:0097443)
0.0 0.1 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.2 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.2 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.1 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.0 0.2 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.2 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.1 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.1 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.4 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.5 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.3 GO:0032585 multivesicular body membrane(GO:0032585)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0034602 oxoglutarate dehydrogenase (NAD+) activity(GO:0034602)
0.2 0.7 GO:0004730 pseudouridylate synthase activity(GO:0004730)
0.2 0.6 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.2 1.3 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 0.4 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.1 0.4 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.1 1.2 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 0.3 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.1 0.4 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.1 0.3 GO:0072590 N-acetyl-L-aspartate-L-glutamate ligase activity(GO:0072590)
0.1 0.5 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 0.5 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.1 0.2 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.1 0.2 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.1 0.4 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1 0.3 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.1 0.4 GO:0004803 transposase activity(GO:0004803)
0.1 0.2 GO:0000247 C-8 sterol isomerase activity(GO:0000247)
0.1 0.2 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.1 0.7 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.1 0.2 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.1 0.3 GO:0003963 RNA-3'-phosphate cyclase activity(GO:0003963)
0.1 0.3 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.1 0.2 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
0.1 0.2 GO:0015563 uptake transmembrane transporter activity(GO:0015563)
0.1 0.2 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.1 0.5 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.1 0.2 GO:0000773 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.1 0.3 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 0.3 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 0.4 GO:0034046 poly(G) binding(GO:0034046)
0.1 0.3 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.1 0.2 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.1 0.3 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.1 0.4 GO:0048408 epidermal growth factor binding(GO:0048408)
0.0 0.1 GO:0070984 SET domain binding(GO:0070984)
0.0 0.5 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.3 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.2 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.0 0.4 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.2 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.3 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.3 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.3 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.1 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
0.0 0.2 GO:0015094 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.0 0.1 GO:0015925 galactosidase activity(GO:0015925)
0.0 0.1 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.0 0.5 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.3 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0 0.3 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.5 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.2 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.4 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.8 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.2 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0 1.1 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.1 GO:0097363 protein O-GlcNAc transferase activity(GO:0097363)
0.0 0.2 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0 0.1 GO:0031626 beta-endorphin binding(GO:0031626)
0.0 0.2 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.0 0.6 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.8 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.2 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0 0.5 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.5 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.2 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.2 GO:0001224 RNA polymerase II transcription cofactor binding(GO:0001224) RNA polymerase II transcription coactivator binding(GO:0001225)
0.0 0.3 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.3 GO:0048185 activin binding(GO:0048185)
0.0 0.1 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.0 0.3 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.1 GO:0050254 rhodopsin kinase activity(GO:0050254)
0.0 0.3 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.4 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.1 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
0.0 0.6 GO:0005112 Notch binding(GO:0005112)
0.0 0.1 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.0 0.1 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.0 0.4 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.1 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.0 0.1 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.1 GO:0047783 steroid 11-beta-monooxygenase activity(GO:0004507) corticosterone 18-monooxygenase activity(GO:0047783)
0.0 0.4 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.1 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.1 GO:0005011 macrophage colony-stimulating factor receptor activity(GO:0005011)
0.0 0.1 GO:0035184 histone threonine kinase activity(GO:0035184)
0.0 0.3 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.1 GO:0070735 protein-glycine ligase activity(GO:0070735)
0.0 0.1 GO:0097001 ceramide binding(GO:0097001)
0.0 0.1 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.0 0.0 GO:0052726 inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol-1,3,4-trisphosphate 6-kinase activity(GO:0052725) inositol-1,3,4-trisphosphate 5-kinase activity(GO:0052726) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) inositol-3,4,6-trisphosphate 1-kinase activity(GO:0052835)
0.0 0.1 GO:0036033 mediator complex binding(GO:0036033)
0.0 0.2 GO:0005114 transforming growth factor beta receptor activity, type I(GO:0005025) type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.4 GO:0005521 lamin binding(GO:0005521)
0.0 0.2 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.1 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.3 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.1 GO:0032450 maltose alpha-glucosidase activity(GO:0032450)
0.0 0.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.1 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.0 0.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.0 GO:0098918 structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.0 1.5 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.3 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 0.1 GO:1990932 5.8S rRNA binding(GO:1990932)
0.0 0.9 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.3 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.4 GO:0005109 frizzled binding(GO:0005109)
0.0 0.1 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.1 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.5 GO:0030332 cyclin binding(GO:0030332)
0.0 0.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.1 GO:1903136 cuprous ion binding(GO:1903136)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.4 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 1.0 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.5 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.5 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 1.3 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.9 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.9 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.5 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.0 0.4 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.7 SIG CHEMOTAXIS Genes related to chemotaxis
0.0 0.5 PID AURORA A PATHWAY Aurora A signaling
0.0 0.8 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.2 PID ALK2 PATHWAY ALK2 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.1 0.5 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1 1.2 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.8 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.3 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.8 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 1.1 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.5 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.7 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 1.0 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.5 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.4 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 1.1 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 0.3 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.4 REACTOME SHC MEDIATED SIGNALLING Genes involved in SHC-mediated signalling
0.0 0.4 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.7 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 0.2 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.4 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 0.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.5 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.4 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.5 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 0.2 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.3 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.3 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.3 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.2 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.2 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 1.4 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 0.3 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.4 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling