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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for SCRT1_SCRT2

Z-value: 1.00

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Transcription factors associated with SCRT1_SCRT2

Gene Symbol Gene ID Gene Info
ENSG00000261678.3 SCRT1
ENSG00000215397.4 SCRT2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SCRT1hg38_v1_chr8_-_144336451_144336503-0.442.7e-02Click!
SCRT2hg38_v1_chr20_-_675793_675808-0.252.3e-01Click!

Activity profile of SCRT1_SCRT2 motif

Sorted Z-values of SCRT1_SCRT2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of SCRT1_SCRT2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr4_+_41538143 8.27 ENST00000503057.6
ENST00000511496.5
LIM and calponin homology domains 1
chr8_-_126557691 4.36 ENST00000652209.1
LRAT domain containing 2
chr4_-_89836213 3.99 ENST00000618500.4
ENST00000508895.5
synuclein alpha
chr4_-_148442342 3.77 ENST00000358102.8
nuclear receptor subfamily 3 group C member 2
chr4_-_148442508 3.64 ENST00000625323.2
nuclear receptor subfamily 3 group C member 2
chr10_+_35195843 2.75 ENST00000488741.5
ENST00000474931.5
ENST00000468236.5
ENST00000344351.5
ENST00000490511.1
cAMP responsive element modulator
chr11_+_59787067 2.15 ENST00000528805.1
syntaxin 3
chr10_+_35195124 1.96 ENST00000487763.5
ENST00000473940.5
ENST00000488328.5
ENST00000356917.9
cAMP responsive element modulator
chr7_-_28958321 1.88 ENST00000539664.3
TLR4 interactor with leucine rich repeats
chr5_-_74640575 1.87 ENST00000651128.1
ectodermal-neural cortex 1
chr5_-_74640719 1.81 ENST00000302351.9
ENST00000509127.2
ectodermal-neural cortex 1
chr3_+_16174628 1.80 ENST00000339732.10
polypeptide N-acetylgalactosaminyltransferase 15
chr10_+_74824919 1.75 ENST00000648828.1
ENST00000648725.1
lysine acetyltransferase 6B
chr5_-_74640649 1.72 ENST00000537006.1
ectodermal-neural cortex 1
chr1_+_15756659 1.71 ENST00000375771.5
filamin binding LIM protein 1
chr8_+_97869040 1.68 ENST00000254898.7
ENST00000524308.5
ENST00000522025.6
matrilin 2
chr19_-_11262499 1.54 ENST00000294618.12
dedicator of cytokinesis 6
chr17_+_70169516 1.53 ENST00000243457.4
potassium inwardly rectifying channel subfamily J member 2
chr22_-_21735776 1.49 ENST00000339468.8
yippee like 1
chr7_+_12687625 1.47 ENST00000651779.1
ENST00000404894.1
ADP ribosylation factor like GTPase 4A
chr2_+_172735838 1.42 ENST00000397081.8
Rap guanine nucleotide exchange factor 4
chr2_+_188291994 1.41 ENST00000409927.5
ENST00000409805.5
GULP PTB domain containing engulfment adaptor 1
chr6_+_15248855 1.34 ENST00000397311.4
jumonji and AT-rich interaction domain containing 2
chr8_+_119208322 1.32 ENST00000614891.5
mal, T cell differentiation protein 2
chrX_+_72069659 1.31 ENST00000631375.1
NHS like 2
chr2_+_172735912 1.31 ENST00000409036.5
Rap guanine nucleotide exchange factor 4
chr12_-_70609788 1.28 ENST00000547715.1
ENST00000538708.5
ENST00000550857.5
ENST00000261266.9
protein tyrosine phosphatase receptor type B
chr2_+_188291854 1.24 ENST00000409830.6
GULP PTB domain containing engulfment adaptor 1
chr22_-_21735744 1.24 ENST00000403503.1
yippee like 1
chr1_-_93847150 1.21 ENST00000370244.5
BCAR3 adaptor protein, NSP family member
chrX_+_55717796 1.20 ENST00000262850.7
Ras related GTP binding B
chrX_-_55030970 1.20 ENST00000493869.2
ENST00000396198.7
ENST00000650242.1
ENST00000335854.8
ENST00000477869.6
ENST00000455688.2
ENST00000644983.1
5'-aminolevulinate synthase 2
chr9_+_131096476 1.19 ENST00000372309.7
ENST00000247291.8
ENST00000372302.5
ENST00000372300.5
ENST00000372298.1
allograft inflammatory factor 1 like
chr5_-_177996242 1.18 ENST00000308304.2
PROP paired-like homeobox 1
chr5_-_111756245 1.17 ENST00000447165.6
neuronal regeneration related protein
chr5_+_73626158 1.15 ENST00000296794.10
ENST00000545377.5
ENST00000509848.5
ENST00000513042.7
Rho guanine nucleotide exchange factor 28
chr9_+_71911468 1.11 ENST00000377031.7
chromosome 9 open reading frame 85
chr9_+_122941003 1.09 ENST00000373647.9
ENST00000402311.5
RAB GTPase activating protein 1
chr12_-_30695852 1.03 ENST00000256079.9
importin 8
chr15_-_29821473 1.01 ENST00000400011.6
tight junction protein 1
chr7_-_122886706 1.01 ENST00000313070.11
ENST00000334010.11
ENST00000615869.4
calcium dependent secretion activator 2
chr14_-_77028663 1.00 ENST00000238647.5
interferon regulatory factor 2 binding protein like
chr1_-_109619605 0.98 ENST00000679935.1
G protein subunit alpha transducin 2
chr6_+_89562308 0.92 ENST00000522441.5
ankyrin repeat domain 6
chr11_+_44726811 0.92 ENST00000533202.5
ENST00000520358.7
ENST00000533080.5
ENST00000520999.6
tetraspanin 18
chr1_+_222618075 0.92 ENST00000344922.10
MIA SH3 domain ER export factor 3
chr6_+_135851681 0.91 ENST00000308191.11
phosphodiesterase 7B
chr4_-_10116324 0.90 ENST00000508079.1
WD repeat domain 1
chr5_+_74715503 0.88 ENST00000513336.5
hexosaminidase subunit beta
chr16_-_29745951 0.87 ENST00000329410.4
chromosome 16 open reading frame 54
chr10_+_95755737 0.86 ENST00000543964.6
ectonucleoside triphosphate diphosphohydrolase 1
chr6_-_27472681 0.86 ENST00000377419.1
zinc finger protein 184
chr17_+_65137408 0.82 ENST00000443584.7
ENST00000449996.7
regulator of G protein signaling 9
chr1_-_154956086 0.81 ENST00000368463.8
ENST00000368460.7
ENST00000368465.5
PBX homeobox interacting protein 1
chr10_+_95755652 0.80 ENST00000371207.8
ectonucleoside triphosphate diphosphohydrolase 1
chr15_-_29822028 0.80 ENST00000545208.6
tight junction protein 1
chr4_+_86934976 0.80 ENST00000507468.5
ENST00000395146.9
AF4/FMR2 family member 1
chr6_-_31728877 0.79 ENST00000437288.5
dimethylarginine dimethylaminohydrolase 2
chr17_+_65137344 0.79 ENST00000262406.10
regulator of G protein signaling 9
chr16_+_67029359 0.79 ENST00000565389.1
core-binding factor subunit beta
chr4_+_119212636 0.76 ENST00000274030.10
ubiquitin specific peptidase 53
chr6_-_31729785 0.76 ENST00000416410.6
dimethylarginine dimethylaminohydrolase 2
chr6_-_77463485 0.75 ENST00000369947.5
5-hydroxytryptamine receptor 1B
chr6_-_31729478 0.73 ENST00000436437.2
dimethylarginine dimethylaminohydrolase 2
chr17_+_80220406 0.71 ENST00000573809.5
ENST00000361193.8
ENST00000574967.5
ENST00000576126.5
ENST00000411502.7
ENST00000546047.6
ENST00000572725.5
solute carrier family 26 member 11
chr6_-_31729260 0.70 ENST00000375789.7
dimethylarginine dimethylaminohydrolase 2
chr19_-_42255119 0.70 ENST00000222329.9
ENST00000594664.1
ETS2 repressor factor
novel protein
chr1_-_3611470 0.70 ENST00000356575.9
multiple EGF like domains 6
chr8_-_90645512 0.69 ENST00000422900.1
transmembrane protein 64
chr20_-_23421409 0.68 ENST00000377026.4
ENST00000398425.7
ENST00000432543.6
ENST00000617876.4
NSF attachment protein beta
chr6_-_27473058 0.68 ENST00000683788.1
ENST00000211936.10
zinc finger protein 184
chr11_+_842807 0.68 ENST00000397411.6
tetraspanin 4
chr11_+_61816249 0.68 ENST00000257261.10
fatty acid desaturase 2
chr8_-_132760548 0.67 ENST00000519187.5
ENST00000523829.5
ENST00000677595.1
ENST00000356838.7
ENST00000377901.8
ENST00000519304.1
transmembrane protein 71
chr15_-_34336749 0.66 ENST00000397707.6
ENST00000560611.5
solute carrier family 12 member 6
chr14_+_99793375 0.66 ENST00000262233.11
ENST00000556714.5
EMAP like 1
chr18_-_55587335 0.65 ENST00000638154.3
transcription factor 4
chr2_-_19990058 0.65 ENST00000281405.9
ENST00000345530.8
WD repeat domain 35
chr1_-_9069797 0.65 ENST00000473209.1
solute carrier family 2 member 5
chr7_+_130486324 0.63 ENST00000427521.6
ENST00000378576.9
mesoderm specific transcript
chr19_+_13906255 0.62 ENST00000589606.5
coiled-coil and C2 domain containing 1A
chrX_-_31266857 0.61 ENST00000378702.8
ENST00000361471.8
dystrophin
chr7_+_130486171 0.60 ENST00000341441.9
ENST00000416162.7
mesoderm specific transcript
chr15_-_34337462 0.59 ENST00000676379.1
solute carrier family 12 member 6
chr12_-_53677397 0.58 ENST00000338662.6
ENST00000552242.5
ATP synthase membrane subunit c locus 2
chr9_+_32551670 0.57 ENST00000450093.3
small integral membrane protein 27
chr3_+_141426108 0.57 ENST00000441582.2
ENST00000510726.1
zinc finger and BTB domain containing 38
chr1_+_179882040 0.56 ENST00000528443.6
torsin 1A interacting protein 1
chr10_+_75431605 0.55 ENST00000611255.5
leucine rich melanocyte differentiation associated
chr12_-_13000166 0.55 ENST00000647702.1
heme binding protein 1
chr5_-_147831627 0.55 ENST00000510027.2
serine peptidase inhibitor Kazal type 1
chr22_+_44180915 0.53 ENST00000444313.8
ENST00000416291.5
parvin gamma
chr5_-_147831663 0.53 ENST00000296695.10
serine peptidase inhibitor Kazal type 1
chrY_-_6911752 0.52 ENST00000651267.2
amelogenin Y-linked
chr10_-_100185993 0.52 ENST00000421367.7
ENST00000370408.2
ENST00000407654.7
ER lipid raft associated 1
chr3_-_72446623 0.51 ENST00000477973.4
RING1 and YY1 binding protein
chr7_-_122886439 0.51 ENST00000412584.6
ENST00000449022.7
calcium dependent secretion activator 2
chr12_-_13000208 0.50 ENST00000014930.9
ENST00000536942.1
heme binding protein 1
chr13_+_48976597 0.50 ENST00000541916.5
fibronectin type III domain containing 3A
chr17_+_79730937 0.50 ENST00000328313.10
ectonucleotide pyrophosphatase/phosphodiesterase 7
chr2_+_69829630 0.50 ENST00000282570.4
germ cell-less 1, spermatogenesis associated
chr3_+_49007365 0.49 ENST00000608424.6
ENST00000438660.5
ENST00000415265.6
WD repeat domain 6
chr11_+_842824 0.49 ENST00000397396.5
ENST00000397397.7
tetraspanin 4
chr15_-_82349437 0.49 ENST00000621197.4
ENST00000610657.2
ENST00000619556.4
golgin A6 family like 10
chr1_+_179882275 0.48 ENST00000606911.7
ENST00000271583.7
torsin 1A interacting protein 1
chr12_-_70754631 0.48 ENST00000440835.6
ENST00000549308.5
ENST00000550661.1
ENST00000378778.5
protein tyrosine phosphatase receptor type R
chr5_-_115296610 0.48 ENST00000379611.10
ENST00000506442.5
coiled-coil domain containing 112
chr5_-_151686908 0.47 ENST00000231061.9
secreted protein acidic and cysteine rich
chr13_+_31739520 0.47 ENST00000298386.7
relaxin family peptide receptor 2
chrX_-_31266925 0.47 ENST00000680557.1
ENST00000378680.6
ENST00000378723.7
ENST00000680768.2
ENST00000681870.1
ENST00000680355.1
ENST00000682322.1
ENST00000682600.1
ENST00000680162.2
ENST00000681153.1
ENST00000681334.1
dystrophin
chr13_+_31739542 0.46 ENST00000380314.2
relaxin family peptide receptor 2
chr11_+_842928 0.46 ENST00000397408.5
tetraspanin 4
chr11_-_18726187 0.45 ENST00000513874.6
immunoglobulin superfamily member 22
chr16_-_50368920 0.45 ENST00000394688.8
bromodomain containing 7
chr4_+_86935040 0.45 ENST00000674009.1
ENST00000503477.5
AF4/FMR2 family member 1
chr4_-_139302516 0.43 ENST00000394228.5
ENST00000539387.5
NADH:ubiquinone oxidoreductase subunit C1
chr7_-_127392687 0.43 ENST00000393313.5
ENST00000619291.4
ENST00000265827.8
ENST00000434602.5
zinc finger protein 800
chr19_+_40601342 0.42 ENST00000396819.8
latent transforming growth factor beta binding protein 4
chr11_-_104164361 0.42 ENST00000302251.9
platelet derived growth factor D
chr3_-_143848442 0.41 ENST00000474151.1
ENST00000316549.11
solute carrier family 9 member A9
chr3_+_49007062 0.40 ENST00000395474.7
ENST00000610967.4
ENST00000429900.6
WD repeat domain 6
chr15_+_84235773 0.40 ENST00000510439.7
ENST00000422563.6
golgin A6 family like 4
chr15_+_80059568 0.40 ENST00000613266.4
ENST00000561060.5
zinc finger AN1-type containing 6
chr3_-_49813880 0.39 ENST00000333486.4
ubiquitin like modifier activating enzyme 7
chr8_+_81732434 0.39 ENST00000297265.5
charged multivesicular body protein 4C
chr16_-_50368779 0.38 ENST00000394689.2
bromodomain containing 7
chrX_+_51893533 0.38 ENST00000375722.5
ENST00000326587.12
ENST00000375695.2
MAGE family member D1
chr11_-_27722021 0.37 ENST00000314915.6
brain derived neurotrophic factor
chr5_-_128537821 0.36 ENST00000508989.5
fibrillin 2
chr1_-_247172002 0.36 ENST00000491356.5
ENST00000472531.5
ENST00000340684.10
ENST00000543802.3
zinc finger protein 124
chr15_+_76059973 0.35 ENST00000388942.8
transmembrane protein 266
chr1_+_108746654 0.34 ENST00000370008.4
syntaxin binding protein 3
chr1_-_25875669 0.34 ENST00000675840.1
progestin and adipoQ receptor family member 7
chr4_+_6673940 0.33 ENST00000635031.1
novel protein, similar to Morf4 family associated protein 1
chr17_-_42136431 0.33 ENST00000552162.5
ENST00000550504.5
RAB5C, member RAS oncogene family
chr6_+_28124596 0.33 ENST00000340487.5
zinc finger and SCAN domain containing 16
chr2_-_61017174 0.33 ENST00000407787.5
ENST00000398658.2
pseudouridine synthase 10
chr8_-_90645905 0.32 ENST00000418210.2
transmembrane protein 64
chr21_-_33479914 0.32 ENST00000542230.7
transmembrane protein 50B
chrX_+_71283186 0.32 ENST00000535149.5
non-POU domain containing octamer binding
chr8_+_74320613 0.31 ENST00000675821.1
ganglioside induced differentiation associated protein 1
chr15_-_29822077 0.31 ENST00000677774.1
tight junction protein 1
chr12_+_101594849 0.31 ENST00000547405.5
ENST00000452455.6
ENST00000392934.7
ENST00000547509.5
ENST00000361685.6
ENST00000549145.5
ENST00000361466.7
ENST00000553190.5
ENST00000545503.6
ENST00000536007.5
ENST00000541119.5
ENST00000551300.5
ENST00000550270.1
myosin binding protein C1
chr12_-_57430956 0.31 ENST00000347140.7
ENST00000402412.5
R3H domain containing 2
chr19_+_13906190 0.31 ENST00000318003.11
coiled-coil and C2 domain containing 1A
chr3_-_114624921 0.30 ENST00000393785.6
zinc finger and BTB domain containing 20
chr16_-_31428325 0.30 ENST00000287490.5
cytochrome c oxidase subunit 6A2
chr20_+_31440626 0.30 ENST00000376309.4
defensin beta 123
chr16_+_981762 0.30 ENST00000293894.4
SRY-box transcription factor 8
chr15_+_80059635 0.29 ENST00000559157.5
zinc finger AN1-type containing 6
chr11_+_32091065 0.28 ENST00000054950.4
reticulocalbin 1
chr11_-_71448315 0.28 ENST00000525346.5
ENST00000531364.5
ENST00000529990.5
ENST00000527316.5
ENST00000355527.8
ENST00000407721.6
7-dehydrocholesterol reductase
chr11_+_111976902 0.27 ENST00000614104.4
DIX domain containing 1
chr6_-_135497230 0.27 ENST00000681365.1
Abelson helper integration site 1
chr13_+_75788838 0.26 ENST00000497947.6
LIM domain 7
chr11_+_70270671 0.23 ENST00000253925.12
ENST00000389547.7
PTPRF interacting protein alpha 1
chr3_-_114624979 0.23 ENST00000676079.1
zinc finger and BTB domain containing 20
chr11_-_71448406 0.23 ENST00000682708.1
ENST00000683287.1
ENST00000683714.1
ENST00000682880.1
7-dehydrocholesterol reductase
chr17_+_28744034 0.23 ENST00000444415.7
ENST00000262396.10
TNF receptor associated factor 4
chr14_+_67619911 0.23 ENST00000261783.4
arginase 2
chr19_-_12513833 0.23 ENST00000455490.1
zinc finger protein 709
chr1_+_43650118 0.22 ENST00000372396.4
lysine demethylase 4A
chr12_-_122422544 0.22 ENST00000358808.6
ENST00000361654.8
ENST00000539080.1
ENST00000537178.5
CAP-Gly domain containing linker protein 1
chr12_+_103587266 0.22 ENST00000388887.7
stabilin 2
chrX_-_100731504 0.22 ENST00000372989.5
ENST00000276141.10
synaptotagmin like 4
chrX_+_52184874 0.21 ENST00000599522.7
ENST00000471932.6
MAGE family member D4
chr15_-_44194407 0.20 ENST00000484674.5
FERM domain containing 5
chr3_-_197298092 0.20 ENST00000392382.6
discs large MAGUK scaffold protein 1
chr12_-_21657792 0.20 ENST00000396076.5
lactate dehydrogenase B
chr12_-_21657831 0.20 ENST00000450584.5
ENST00000350669.5
ENST00000673047.2
lactate dehydrogenase B
chrX_+_52184904 0.19 ENST00000375626.7
ENST00000467526.1
MAGE family member D4
chr5_+_138753412 0.18 ENST00000520339.5
ENST00000627109.2
ENST00000302763.12
ENST00000518910.5
catenin alpha 1
chr1_+_62437015 0.18 ENST00000339950.5
ubiquitin specific peptidase 1
chr22_-_17258235 0.18 ENST00000649310.1
ENST00000649746.1
adenosine deaminase 2
chr22_-_23632317 0.18 ENST00000317749.9
aspartate rich 1
chr6_-_56843638 0.17 ENST00000421834.6
ENST00000370788.6
dystonin
chr17_+_44141899 0.17 ENST00000319977.8
ENST00000585683.6
homologous recombination factor with OB-fold
chr6_-_169723931 0.17 ENST00000366780.8
ENST00000612128.1
PHD finger protein 10
chr4_-_86934700 0.17 ENST00000473559.5
novel protein
chr14_+_105419938 0.16 ENST00000405646.5
metastasis associated 1
chrX_-_52069172 0.16 ENST00000486010.1
ENST00000497164.5
ENST00000360134.10
ENST00000485287.5
ENST00000335504.9
MAGE family member D4B
chr3_+_133746385 0.16 ENST00000482271.5
ENST00000402696.9
transferrin
chr17_-_29078857 0.16 ENST00000359450.6
TGFB1-induced anti-apoptotic factor 1
chr1_+_103655760 0.16 ENST00000370083.9
amylase alpha 1A
chr1_+_150549734 0.16 ENST00000674043.1
ENST00000674058.1
ADAMTS like 4
chr15_+_80060113 0.15 ENST00000618205.4
zinc finger AN1-type containing 6
chr19_-_16627943 0.15 ENST00000611692.4
mediator complex subunit 26
chr5_+_32710630 0.15 ENST00000326958.5
natriuretic peptide receptor 3
chr1_-_50960230 0.15 ENST00000396153.7
Fas associated factor 1
chr1_+_42682954 0.15 ENST00000436427.1
Y-box binding protein 1
chr8_-_33473076 0.14 ENST00000524021.1
ENST00000327671.10
fucosyltransferase 10
chr9_+_214843 0.14 ENST00000432829.7
dedicator of cytokinesis 8
chr19_-_46471407 0.14 ENST00000438932.2
PNMA family member 8A
chr6_-_10419638 0.13 ENST00000319516.8
transcription factor AP-2 alpha
chr19_-_46471484 0.13 ENST00000313683.15
ENST00000602246.1
PNMA family member 8A
chr17_-_64263221 0.13 ENST00000258991.7
ENST00000583738.1
ENST00000584379.6
testis expressed 2
chr19_-_6459735 0.13 ENST00000334510.9
ENST00000301454.9
solute carrier family 25 member 23
chr4_-_140427635 0.12 ENST00000325617.10
ENST00000414773.5
calmegin
chr6_+_70413417 0.12 ENST00000505769.5
ENST00000515323.5
family with sequence similarity 135 member A
chr11_+_7251886 0.12 ENST00000318881.11
synaptotagmin 9

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 4.0 GO:2000470 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.5 5.4 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.4 2.1 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.4 1.5 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.3 1.2 GO:0048850 hypophysis morphogenesis(GO:0048850)
0.2 0.7 GO:0035494 SNARE complex disassembly(GO:0035494)
0.2 2.1 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.2 0.8 GO:0016334 morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247)
0.2 1.1 GO:0010751 negative regulation of nitric oxide mediated signal transduction(GO:0010751)
0.2 1.2 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.2 1.0 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.2 3.0 GO:0006527 arginine catabolic process(GO:0006527)
0.2 0.8 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.1 0.9 GO:0007341 penetration of zona pellucida(GO:0007341)
0.1 0.4 GO:2000439 positive regulation of monocyte extravasation(GO:2000439)
0.1 1.7 GO:1990504 dense core granule exocytosis(GO:1990504)
0.1 1.2 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.1 1.7 GO:0033623 regulation of integrin activation(GO:0033623)
0.1 0.4 GO:0031550 positive regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031550)
0.1 1.0 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.1 0.3 GO:0039008 pronephric nephron morphogenesis(GO:0039007) pronephric nephron tubule morphogenesis(GO:0039008) pronephric duct development(GO:0039022) pronephric duct morphogenesis(GO:0039023) Kupffer's vesicle development(GO:0070121)
0.1 1.0 GO:0071763 nuclear membrane organization(GO:0071763)
0.1 1.3 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1 1.2 GO:0032364 oxygen homeostasis(GO:0032364)
0.1 0.3 GO:0072034 renal vesicle induction(GO:0072034)
0.1 0.5 GO:0033490 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.1 0.5 GO:0098704 fructose transport(GO:0015755) fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.1 1.1 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.1 1.0 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.1 0.5 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.1 1.3 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.1 0.4 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.1 1.7 GO:0034656 nucleobase-containing small molecule catabolic process(GO:0034656)
0.1 0.5 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.1 0.5 GO:0033591 response to L-ascorbic acid(GO:0033591)
0.1 0.9 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 4.7 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.1 0.2 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 0.2 GO:1902499 positive regulation of protein autoubiquitination(GO:1902499)
0.1 0.2 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.1 0.9 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 0.7 GO:0019532 oxalate transport(GO:0019532)
0.0 0.4 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.0 0.3 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.8 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.7 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.4 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.1 GO:0097274 urea homeostasis(GO:0097274)
0.0 0.5 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.1 GO:0097212 cleavage furrow ingression(GO:0036090) lysosomal membrane organization(GO:0097212) positive regulation of late endosome to lysosome transport(GO:1902824)
0.0 0.1 GO:0003409 optic cup structural organization(GO:0003409)
0.0 0.1 GO:0052314 phytoalexin metabolic process(GO:0052314)
0.0 1.2 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.0 GO:0033076 isoquinoline alkaloid metabolic process(GO:0033076)
0.0 1.9 GO:0034142 toll-like receptor 4 signaling pathway(GO:0034142)
0.0 0.3 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.1 GO:0072709 cellular response to sorbitol(GO:0072709)
0.0 1.5 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.8 GO:0006625 protein targeting to peroxisome(GO:0006625) peroxisomal transport(GO:0043574) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.0 0.2 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 2.7 GO:0006911 phagocytosis, engulfment(GO:0006911)
0.0 8.5 GO:0043401 steroid hormone mediated signaling pathway(GO:0043401)
0.0 0.4 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.2 GO:0098707 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.0 1.0 GO:0001556 oocyte maturation(GO:0001556)
0.0 0.6 GO:0036109 alpha-linolenic acid metabolic process(GO:0036109)
0.0 0.4 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.2 GO:0046103 adenosine catabolic process(GO:0006154) inosine biosynthetic process(GO:0046103)
0.0 0.5 GO:0034505 tooth mineralization(GO:0034505)
0.0 8.1 GO:0031032 actomyosin structure organization(GO:0031032)
0.0 0.3 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 1.9 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.8 GO:0035066 positive regulation of histone acetylation(GO:0035066)
0.0 1.7 GO:0031102 neuron projection regeneration(GO:0031102)
0.0 0.1 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.0 0.5 GO:0060009 Sertoli cell development(GO:0060009)
0.0 1.8 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.7 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.5 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.0 0.3 GO:0045955 negative regulation of calcium ion-dependent exocytosis(GO:0045955)
0.0 0.1 GO:1903862 positive regulation of oxidative phosphorylation(GO:1903862)
0.0 0.2 GO:0048712 negative regulation of astrocyte differentiation(GO:0048712)
0.0 1.7 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 0.3 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.8 GO:0010996 response to auditory stimulus(GO:0010996)
0.0 0.1 GO:0010645 positive regulation of glomerular filtration(GO:0003104) regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
0.0 0.4 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0 0.2 GO:0000050 urea cycle(GO:0000050)
0.0 0.2 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.0 0.7 GO:0007405 neuroblast proliferation(GO:0007405)
0.0 0.2 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.2 GO:0002158 osteoclast proliferation(GO:0002158)
0.0 0.3 GO:0071305 cellular response to vitamin D(GO:0071305)
0.0 0.0 GO:0036496 regulation of translational initiation by eIF2 alpha dephosphorylation(GO:0036496)
0.0 0.2 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.4 GO:0030252 growth hormone secretion(GO:0030252)
0.0 0.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 1.1 GO:1902017 regulation of cilium assembly(GO:1902017)
0.0 0.1 GO:0097084 vascular smooth muscle cell development(GO:0097084)
0.0 0.9 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.5 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.6 GO:0030318 melanocyte differentiation(GO:0030318)
0.0 0.9 GO:0019933 cAMP-mediated signaling(GO:0019933)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.1 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.2 1.9 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.2 1.2 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.2 0.8 GO:0042643 actomyosin, actin portion(GO:0042643)
0.1 1.8 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 4.2 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 1.1 GO:0016013 syntrophin complex(GO:0016013)
0.1 0.7 GO:0030991 intraciliary transport particle A(GO:0030991)
0.1 5.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 2.2 GO:0005921 gap junction(GO:0005921)
0.1 1.0 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 1.6 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 1.2 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.7 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 0.9 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 1.5 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.3 GO:0042382 paraspeckles(GO:0042382)
0.0 0.5 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.2 GO:0031673 H zone(GO:0031673)
0.0 0.2 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.2 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 1.0 GO:0090544 BAF-type complex(GO:0090544)
0.0 0.3 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 2.4 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.0 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.0 1.3 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.4 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.9 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.3 GO:0036038 MKS complex(GO:0036038)
0.0 0.8 GO:0031430 M band(GO:0031430)
0.0 0.2 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 2.4 GO:0001650 fibrillar center(GO:0001650)
0.0 1.6 GO:0005604 basement membrane(GO:0005604)
0.0 1.0 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 6.4 GO:0043235 receptor complex(GO:0043235)
0.0 0.1 GO:0016011 dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012)
0.0 5.5 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.5 GO:0031519 PcG protein complex(GO:0031519)
0.0 1.3 GO:0042734 presynaptic membrane(GO:0042734)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 4.0 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.4 3.0 GO:0016403 dimethylargininase activity(GO:0016403)
0.3 4.7 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.2 1.2 GO:0016749 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.2 0.7 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.2 0.9 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.2 0.7 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.1 0.9 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.1 2.1 GO:0050544 arachidonic acid binding(GO:0050544)
0.1 0.4 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.1 1.2 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 1.7 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.1 1.8 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 0.5 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.1 1.3 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 1.5 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 1.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 1.0 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.1 0.5 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.1 0.4 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 0.8 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.1 7.6 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.1 0.4 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.1 0.7 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 1.8 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 0.2 GO:0004556 alpha-amylase activity(GO:0004556)
0.0 0.9 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 1.9 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 1.3 GO:0017166 vinculin binding(GO:0017166)
0.0 0.9 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 1.2 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.5 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.4 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 1.0 GO:0005521 lamin binding(GO:0005521)
0.0 0.7 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.2 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.2 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 1.3 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.6 GO:0031005 filamin binding(GO:0031005)
0.0 16.4 GO:0003779 actin binding(GO:0003779)
0.0 0.8 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 1.8 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 1.2 GO:0030552 cAMP binding(GO:0030552)
0.0 0.4 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.4 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.0 0.2 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 1.0 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.3 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.6 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.2 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.1 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 0.5 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 0.1 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 0.8 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.2 GO:0005381 iron ion transmembrane transporter activity(GO:0005381) ferric iron binding(GO:0008199)
0.0 0.2 GO:0051010 microtubule plus-end binding(GO:0051010)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.8 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 2.6 PID CONE PATHWAY Visual signal transduction: Cones
0.1 3.3 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 2.1 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 2.7 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.9 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.3 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 3.4 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.5 PID ILK PATHWAY Integrin-linked kinase signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.0 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 2.1 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 7.3 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 2.7 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 0.9 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 0.8 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 1.3 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 1.2 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 1.6 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 1.0 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 0.6 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.4 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.5 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 1.4 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.2 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.5 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.2 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.9 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.5 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.4 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 0.2 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation