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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for SIX6

Z-value: 0.55

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Transcription factors associated with SIX6

Gene Symbol Gene ID Gene Info
SIX6
ENSG00000184302.7 SIX6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SIX6hg38_v1_chr14_+_60509138_605091630.058.2e-01Click!

Activity profile of SIX6 motif

Sorted Z-values of SIX6 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of SIX6

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr15_-_79971164 2.57 ENST00000335661.6
ENST00000267953.4
ENST00000677151.1
BCL2A1
BCL2 related protein A1
chr3_+_151814102 1.75 ENST00000232892.12
AADAC
arylacetamide deacetylase
chr6_+_127577168 1.32 ENST00000329722.8
C6orf58
chromosome 6 open reading frame 58
chr3_+_155083523 1.09 ENST00000680057.1
MME
membrane metalloendopeptidase
chr22_-_17221841 0.88 ENST00000449907.7
ENST00000441548.1
ENST00000399839.5
ADA2
adenosine deaminase 2
chr12_+_116910935 0.70 ENST00000652555.1
ENST00000455858.2
FBXW8
F-box and WD repeat domain containing 8
chr11_-_105035113 0.66 ENST00000526568.5
ENST00000531166.5
ENST00000534497.5
ENST00000527979.5
ENST00000533400.6
ENST00000528974.1
ENST00000525825.5
ENST00000353247.9
ENST00000446369.5
ENST00000436863.7
CASP1
caspase 1
chr10_+_80131660 0.58 ENST00000372270.6
PLAC9
placenta associated 9
chr1_+_212565334 0.55 ENST00000366981.8
ENST00000366987.6
ATF3
activating transcription factor 3
chr1_+_156150008 0.55 ENST00000355014.6
SEMA4A
semaphorin 4A
chr7_+_117611617 0.54 ENST00000468795.1
CFTR
CF transmembrane conductance regulator
chr16_+_21678514 0.53 ENST00000286149.8
ENST00000388958.8
OTOA
otoancorin
chr22_-_19150292 0.52 ENST00000086933.3
GSC2
goosecoid homeobox 2
chr9_-_97944832 0.52 ENST00000259456.7
HEMGN
hemogen
chr14_-_69574845 0.50 ENST00000599174.3
CCDC177
coiled-coil domain containing 177
chr2_+_209771972 0.47 ENST00000439458.5
ENST00000272845.10
UNC80
unc-80 homolog, NALCN channel complex subunit
chr1_-_161045961 0.47 ENST00000368021.7
USF1
upstream transcription factor 1
chr14_+_20469399 0.47 ENST00000361505.10
ENST00000553591.1
PNP
purine nucleoside phosphorylase
chr4_-_69961007 0.43 ENST00000353151.3
CSN2
casein beta
chr1_+_13585453 0.42 ENST00000487038.5
ENST00000475043.5
PDPN
podoplanin
chr6_+_26204552 0.42 ENST00000615164.2
H4C5
H4 clustered histone 5
chr3_-_9952337 0.41 ENST00000411976.2
ENST00000412055.6
PRRT3
proline rich transmembrane protein 3
chr1_+_31413187 0.40 ENST00000373709.8
SERINC2
serine incorporator 2
chr8_+_32721823 0.39 ENST00000539990.3
ENST00000519240.5
NRG1
neuregulin 1
chr13_+_75549477 0.39 ENST00000618773.4
UCHL3
ubiquitin C-terminal hydrolase L3
chrX_+_7843088 0.37 ENST00000341408.5
VCX
variable charge X-linked
chr12_-_27970273 0.36 ENST00000542963.1
ENST00000535992.5
PTHLH
parathyroid hormone like hormone
chrX_+_8465426 0.35 ENST00000381029.4
VCX3B
variable charge X-linked 3B
chr2_+_201132928 0.35 ENST00000462763.5
CFLAR
CASP8 and FADD like apoptosis regulator
chr1_+_86468902 0.35 ENST00000394711.2
CLCA1
chloride channel accessory 1
chr12_-_86838867 0.35 ENST00000621808.4
MGAT4C
MGAT4 family member C
chr15_+_58138368 0.34 ENST00000219919.9
ENST00000536493.1
AQP9
aquaporin 9
chr12_-_121039204 0.34 ENST00000620239.5
OASL
2'-5'-oligoadenylate synthetase like
chr2_-_88128049 0.33 ENST00000393750.3
ENST00000295834.8
FABP1
fatty acid binding protein 1
chr11_-_84273188 0.32 ENST00000330014.11
ENST00000418306.6
ENST00000531015.5
DLG2
discs large MAGUK scaffold protein 2
chr12_-_121039236 0.32 ENST00000257570.9
OASL
2'-5'-oligoadenylate synthetase like
chr4_+_73436198 0.31 ENST00000395792.7
AFP
alpha fetoprotein
chr4_+_73436244 0.30 ENST00000226359.2
AFP
alpha fetoprotein
chr12_-_121039156 0.29 ENST00000339275.10
OASL
2'-5'-oligoadenylate synthetase like
chr11_-_102625332 0.28 ENST00000260228.3
MMP20
matrix metallopeptidase 20
chr3_+_187024614 0.28 ENST00000416235.6
ST6GAL1
ST6 beta-galactoside alpha-2,6-sialyltransferase 1
chrX_+_65488735 0.27 ENST00000338957.4
ZC3H12B
zinc finger CCCH-type containing 12B
chr11_+_74988896 0.26 ENST00000526068.1
ENST00000294064.9
ENST00000532963.1
ENST00000531619.1
ENST00000534628.1
NEU3
neuraminidase 3
chr12_-_21334858 0.25 ENST00000445053.1
ENST00000458504.5
ENST00000422327.5
ENST00000683939.1
SLCO1A2
solute carrier organic anion transporter family member 1A2
chr13_-_46105009 0.24 ENST00000439329.5
ENST00000674625.1
ENST00000181383.10
CPB2
carboxypeptidase B2
chr1_-_182400660 0.24 ENST00000367565.2
TEDDM1
transmembrane epididymal protein 1
chr15_-_100341899 0.24 ENST00000568565.2
ENST00000268070.9
ADAMTS17
ADAM metallopeptidase with thrombospondin type 1 motif 17
chr6_+_29587455 0.23 ENST00000383640.4
OR2H2
olfactory receptor family 2 subfamily H member 2
chr10_+_102226293 0.23 ENST00000370005.4
ELOVL3
ELOVL fatty acid elongase 3
chr4_-_122456725 0.23 ENST00000226730.5
IL2
interleukin 2
chr4_+_106315689 0.22 ENST00000358008.7
AIMP1
aminoacyl tRNA synthetase complex interacting multifunctional protein 1
chr4_-_154590735 0.22 ENST00000403106.8
ENST00000622532.1
ENST00000651975.1
FGA
fibrinogen alpha chain
chrX_+_12791353 0.21 ENST00000380663.7
ENST00000398491.6
ENST00000380668.10
ENST00000489404.5
PRPS2
phosphoribosyl pyrophosphate synthetase 2
chr21_-_18403754 0.21 ENST00000284885.8
TMPRSS15
transmembrane serine protease 15
chr13_+_75549734 0.21 ENST00000563635.5
ENST00000377595.8
ENSG00000261553.5
UCHL3
novel transcript
ubiquitin C-terminal hydrolase L3
chr4_+_106315534 0.21 ENST00000510207.5
AIMP1
aminoacyl tRNA synthetase complex interacting multifunctional protein 1
chr12_-_27970047 0.20 ENST00000395868.7
PTHLH
parathyroid hormone like hormone
chr4_+_73481737 0.20 ENST00000226355.5
AFM
afamin
chr1_-_38876351 0.20 ENST00000360786.3
GJA9
gap junction protein alpha 9
chr12_-_121038967 0.20 ENST00000680620.1
ENST00000679655.1
ENST00000543677.2
OASL
2'-5'-oligoadenylate synthetase like
chr6_-_107824294 0.17 ENST00000369020.8
ENST00000369022.6
SCML4
Scm polycomb group protein like 4
chr12_-_121580441 0.17 ENST00000377069.8
KDM2B
lysine demethylase 2B
chr2_-_151973780 0.17 ENST00000637514.1
ENST00000636350.1
ENST00000434468.2
ENST00000637762.1
ENST00000637779.1
ENST00000637547.1
ENST00000636901.1
ENST00000397327.7
ENST00000636721.1
ENST00000636380.1
ENST00000637284.1
ENST00000636617.1
ENST00000636947.1
ENST00000638091.1
ENST00000636108.1
ENST00000638040.1
ENST00000636773.1
ENST00000637418.1
ENST00000637216.1
CACNB4
calcium voltage-gated channel auxiliary subunit beta 4
chr5_+_40909490 0.15 ENST00000313164.10
C7
complement C7
chrY_+_14056226 0.14 ENST00000250823.5
VCY1B
variable charge Y-linked 1B
chr11_-_82846128 0.14 ENST00000679809.1
ENST00000680186.1
ENST00000681592.1
PRCP
prolylcarboxypeptidase
chr16_-_20352707 0.14 ENST00000396134.6
ENST00000573567.5
ENST00000570757.5
ENST00000396138.9
ENST00000571174.5
ENST00000576688.2
UMOD
uromodulin
chr2_+_88885397 0.14 ENST00000390243.2
IGKV4-1
immunoglobulin kappa variable 4-1
chr4_-_64409444 0.14 ENST00000381210.8
ENST00000507440.5
TECRL
trans-2,3-enoyl-CoA reductase like
chr1_+_156149657 0.13 ENST00000414683.5
SEMA4A
semaphorin 4A
chr12_+_53954870 0.13 ENST00000243103.4
HOXC12
homeobox C12
chr6_-_152637351 0.13 ENST00000367255.10
SYNE1
spectrin repeat containing nuclear envelope protein 1
chr4_+_77605807 0.13 ENST00000682537.1
CXCL13
C-X-C motif chemokine ligand 13
chr1_-_88992732 0.13 ENST00000413769.1
ENST00000321792.5
ENST00000370491.7
RBMXL1
KYAT3
RBMX like 1
kynurenine aminotransferase 3
chr5_+_140821598 0.13 ENST00000614258.1
ENST00000529859.2
ENST00000529619.5
PCDHA5
protocadherin alpha 5
chr9_-_21351378 0.12 ENST00000380210.1
IFNA6
interferon alpha 6
chr11_-_45286265 0.12 ENST00000020926.8
SYT13
synaptotagmin 13
chrY_-_13986473 0.12 ENST00000250825.5
VCY
variable charge Y-linked
chr6_+_29170907 0.12 ENST00000641417.1
OR2J2
olfactory receptor family 2 subfamily J member 2
chr7_-_142258027 0.12 ENST00000552471.1
ENST00000547058.6
PRSS58
serine protease 58
chr13_+_33818063 0.11 ENST00000434425.5
RFC3
replication factor C subunit 3
chr21_-_42315336 0.11 ENST00000398431.2
ENST00000518498.3
TFF3
trefoil factor 3
chr18_+_11752041 0.10 ENST00000423027.8
GNAL
G protein subunit alpha L
chr22_+_17563433 0.10 ENST00000399813.1
SLC25A18
solute carrier family 25 member 18
chr22_+_17563485 0.10 ENST00000327451.11
SLC25A18
solute carrier family 25 member 18
chr13_-_19505940 0.09 ENST00000400103.6
TPTE2
transmembrane phosphoinositide 3-phosphatase and tensin homolog 2
chr2_+_85595684 0.09 ENST00000441634.5
ENST00000306368.9
ENST00000414390.5
ENST00000456023.1
RNF181
ring finger protein 181
chr1_-_35769928 0.09 ENST00000373220.7
ENST00000520551.1
CLSPN
claspin
chr3_-_53882142 0.09 ENST00000335754.8
ACTR8
actin related protein 8
chr9_+_107306459 0.08 ENST00000457811.1
RAD23B
RAD23 homolog B, nucleotide excision repair protein
chr1_+_160739265 0.08 ENST00000368042.7
SLAMF7
SLAM family member 7
chr2_-_133568393 0.08 ENST00000317721.10
ENST00000405974.7
ENST00000409261.6
ENST00000409213.5
NCKAP5
NCK associated protein 5
chr6_-_26043704 0.08 ENST00000615966.2
H2BC3
H2B clustered histone 3
chr19_-_15125659 0.07 ENST00000533747.1
ENST00000598709.1
ENST00000534378.5
ILVBL
ilvB acetolactate synthase like
chr17_-_10026265 0.07 ENST00000437099.6
ENST00000396115.6
GAS7
growth arrest specific 7
chr1_-_225567270 0.07 ENST00000497899.6
ENAH
ENAH actin regulator
chr3_-_3109980 0.07 ENST00000256452.7
ENST00000311981.12
ENST00000430514.6
ENST00000456302.5
IL5RA
interleukin 5 receptor subunit alpha
chr5_+_161850597 0.06 ENST00000634335.1
ENST00000635880.1
GABRA1
gamma-aminobutyric acid type A receptor subunit alpha1
chr18_+_52752032 0.06 ENST00000412726.5
ENST00000578080.1
ENST00000582875.1
DCC
DCC netrin 1 receptor
chr1_-_9943314 0.06 ENST00000377223.6
ENST00000377213.1
LZIC
leucine zipper and CTNNBIP1 domain containing
chr6_-_26189101 0.06 ENST00000614247.2
H4C4
H4 clustered histone 4
chr5_-_157109115 0.06 ENST00000522593.5
HAVCR2
hepatitis A virus cellular receptor 2
chr7_-_93226449 0.06 ENST00000394468.7
ENST00000453812.2
HEPACAM2
HEPACAM family member 2
chr4_-_154612635 0.05 ENST00000407946.5
ENST00000405164.5
ENST00000336098.8
ENST00000393846.6
ENST00000404648.7
ENST00000443553.5
FGG
fibrinogen gamma chain
chr1_+_12791397 0.05 ENST00000332296.7
PRAMEF1
PRAME family member 1
chrX_+_129540236 0.05 ENST00000371113.9
ENST00000357121.5
OCRL
OCRL inositol polyphosphate-5-phosphatase
chr6_+_52186373 0.05 ENST00000648244.1
IL17A
interleukin 17A
chr1_+_160739239 0.04 ENST00000368043.8
SLAMF7
SLAM family member 7
chr5_-_157109025 0.04 ENST00000307851.9
HAVCR2
hepatitis A virus cellular receptor 2
chr1_-_159714581 0.04 ENST00000255030.9
ENST00000437342.1
ENST00000368112.5
ENST00000368111.5
ENST00000368110.1
CRP
C-reactive protein
chr12_+_71686473 0.04 ENST00000549735.5
TMEM19
transmembrane protein 19
chr1_+_12857086 0.04 ENST00000240189.2
PRAMEF2
PRAME family member 2
chr19_-_15898057 0.04 ENST00000011989.11
ENST00000221700.11
CYP4F2
cytochrome P450 family 4 subfamily F member 2
chrX_-_100410264 0.04 ENST00000373034.8
PCDH19
protocadherin 19
chr11_-_5227063 0.02 ENST00000335295.4
ENST00000485743.1
ENST00000647020.1
HBB
hemoglobin subunit beta
chr14_+_22479521 0.01 ENST00000390483.1
TRAJ56
T cell receptor alpha joining 56
chr3_-_196515315 0.01 ENST00000397537.3
SMCO1
single-pass membrane protein with coiled-coil domains 1
chr6_-_26285526 0.01 ENST00000377727.2
H4C8
H4 clustered histone 8
chr19_-_35563653 0.00 ENST00000262623.4
ATP4A
ATPase H+/K+ transporting subunit alpha

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.2 0.5 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.2 0.5 GO:1902161 positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.2 1.4 GO:0046102 inosine metabolic process(GO:0046102)
0.1 0.4 GO:1903487 regulation of lactation(GO:1903487)
0.1 0.4 GO:1904328 regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
0.1 1.7 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.1 1.1 GO:0071492 cellular response to UV-A(GO:0071492)
0.1 0.3 GO:0015855 canalicular bile acid transport(GO:0015722) pyrimidine nucleobase transport(GO:0015855) purine nucleobase transmembrane transport(GO:1904823)
0.1 0.4 GO:1904222 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.1 0.5 GO:0000432 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) late viral transcription(GO:0019086)
0.1 0.2 GO:0003330 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.1 2.6 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.1 GO:0072023 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.0 0.2 GO:0001777 T cell homeostatic proliferation(GO:0001777) regulation of T cell homeostatic proliferation(GO:0046013)
0.0 0.2 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0 0.2 GO:0021592 midbrain-hindbrain boundary morphogenesis(GO:0021555) fourth ventricle development(GO:0021592)
0.0 0.6 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.0 0.1 GO:0071656 negative regulation of interleukin-3 production(GO:0032712) negative regulation of granulocyte colony-stimulating factor production(GO:0071656) negative regulation of macrophage colony-stimulating factor production(GO:1901257)
0.0 0.4 GO:1903943 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.7 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.0 0.1 GO:2001027 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634) negative regulation of endothelial cell chemotaxis(GO:2001027)
0.0 0.3 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.4 GO:0021840 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.0 0.3 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.1 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
0.0 0.3 GO:0070166 enamel mineralization(GO:0070166)
0.0 0.2 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.2 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.1 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.0 0.7 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.0 0.1 GO:0002254 kinin cascade(GO:0002254) plasma kallikrein-kinin cascade(GO:0002353)
0.0 0.1 GO:0097052 L-kynurenine metabolic process(GO:0097052)
0.0 0.6 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.0 0.3 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.1 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.0 0.0 GO:0032304 negative regulation of icosanoid secretion(GO:0032304) negative regulation of fatty acid transport(GO:2000192)
0.0 0.1 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 1.1 GO:0045071 negative regulation of viral genome replication(GO:0045071)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.2 0.7 GO:0097179 protease inhibitor complex(GO:0097179)
0.1 0.4 GO:0017102 methionyl glutamyl tRNA synthetase complex(GO:0017102)
0.1 0.7 GO:1990393 3M complex(GO:1990393)
0.1 0.5 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.1 0.2 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 0.5 GO:0016589 NURF complex(GO:0016589)
0.0 0.4 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.3 GO:0045179 apical cortex(GO:0045179)
0.0 0.3 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.4 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.1 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.4 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.1 GO:0071942 XPC complex(GO:0071942)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.1 2.6 GO:0051400 BH domain binding(GO:0051400)
0.1 0.5 GO:0002060 purine nucleobase binding(GO:0002060)
0.1 0.3 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.1 0.9 GO:0031685 adenosine receptor binding(GO:0031685)
0.1 1.1 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 0.2 GO:0008431 vitamin E binding(GO:0008431)
0.1 0.6 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.1 1.7 GO:0004806 triglyceride lipase activity(GO:0004806)
0.1 0.3 GO:0052795 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.3 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.3 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.3 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 0.1 GO:0047315 kynurenine-glyoxylate transaminase activity(GO:0047315)
0.0 0.7 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.2 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 0.2 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.2 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.0 0.1 GO:0051800 phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.0 0.7 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.4 GO:0008517 folic acid transporter activity(GO:0008517)
0.0 0.4 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.1 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.4 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.1 GO:0004914 interleukin-5 receptor activity(GO:0004914)
0.0 0.2 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.3 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.0 GO:0052870 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.0 0.4 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.4 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.6 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.0 GO:0033265 choline binding(GO:0033265)
0.0 1.6 GO:0004222 metalloendopeptidase activity(GO:0004222)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 2.6 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.6 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.4 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.4 PID ERBB NETWORK PATHWAY ErbB receptor signaling network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.7 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.6 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.7 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.5 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.3 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.3 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.3 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.5 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.4 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.5 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 1.2 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.8 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4