ISMARA results: SMAD3

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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for SMAD3

Z-value: 0.58

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Transcription factors associated with SMAD3

Gene Symbol	Gene ID	Gene Info
SMAD3 Ensembl NCBI GeneCards UniProt	ENSG00000166949.17	SMAD3

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
SMAD3	hg38_v1_chr15_+_67128103_67128269	-0.05	8.2e-01	Click!

Activity profile of SMAD3 motif

Sorted Z-values of SMAD3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of SMAD3

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View png image

Top targets:

Promoter	Score	Transcript	Gene	Gene Info
chr4_-_185775271 Show fit	1.08	ENST00000430503.5 ENST00000319454.10 ENST00000450341.5	SORBS2 Ensembl NCBI GeneCards UniProt Show fit	sorbin and SH3 domain containing 2
chr20_-_23049659 Show fit	0.81	ENST00000377103.3	THBD Ensembl NCBI GeneCards UniProt Show fit	thrombomodulin
chr12_-_9760893 Show fit	0.72	ENST00000228434.7 ENST00000536709.1	CD69 Ensembl NCBI GeneCards UniProt Show fit	CD69 molecule
chr3_+_125969214 Show fit	0.55	ENST00000508088.1	ROPN1B Ensembl NCBI GeneCards UniProt Show fit	rhophilin associated tail protein 1B
chrX_-_63351308 Show fit	0.51	ENST00000374884.3	SPIN4 Ensembl NCBI GeneCards UniProt Show fit	spindlin family member 4
chr10_-_88952763 Show fit	0.50	ENST00000224784.10	ACTA2 Ensembl NCBI GeneCards UniProt Show fit	actin alpha 2, smooth muscle
chr16_+_25216943 Show fit	0.48	ENST00000219660.6	AQP8 Ensembl NCBI GeneCards UniProt Show fit	aquaporin 8
chr4_-_89838289 Show fit	0.43	ENST00000336904.7	SNCA Ensembl NCBI GeneCards UniProt Show fit	synuclein alpha
chr6_-_27893175 Show fit	0.43	ENST00000359611.4	H2AC17 Ensembl NCBI GeneCards UniProt Show fit	H2A clustered histone 17
chr7_-_120857124 Show fit	0.41	ENST00000441017.5 ENST00000424710.5 ENST00000433758.5	TSPAN12 Ensembl NCBI GeneCards UniProt Show fit	tetraspanin 12
chr3_+_12796662 Show fit	0.41	ENST00000456430.6 ENST00000626378.1	CAND2 Ensembl NCBI GeneCards UniProt Show fit	cullin associated and neddylation dissociated 2 (putative)
chr3_+_141384790 Show fit	0.36	ENST00000507722.5	ZBTB38 Ensembl NCBI GeneCards UniProt Show fit	zinc finger and BTB domain containing 38
chr9_-_14321948 Show fit	0.34	ENST00000635877.1 ENST00000636432.1 ENST00000646622.1	NFIB Ensembl NCBI GeneCards UniProt Show fit	nuclear factor I B
chr1_-_9069572 Show fit	0.32	ENST00000377414.7	SLC2A5 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 2 member 5
chr4_+_54657918 Show fit	0.32	ENST00000412167.6 ENST00000288135.6	KIT Ensembl NCBI GeneCards UniProt Show fit	KIT proto-oncogene, receptor tyrosine kinase
chr9_-_127847117 Show fit	0.32	ENST00000480266.5	ENG Ensembl NCBI GeneCards UniProt Show fit	endoglin
chr2_-_219245389 Show fit	0.31	ENST00000428427.1 ENST00000432839.1 ENST00000295759.12 ENST00000424620.1	GLB1L Ensembl NCBI GeneCards UniProt Show fit	galactosidase beta 1 like
chr2_-_219245465 Show fit	0.31	ENST00000392089.6	GLB1L Ensembl NCBI GeneCards UniProt Show fit	galactosidase beta 1 like
chr16_-_3256587 Show fit	0.30	ENST00000536379.5 ENST00000541159.5 ENST00000339854.8 ENST00000219596.6	MEFV Ensembl NCBI GeneCards UniProt Show fit	MEFV innate immuity regulator, pyrin
chr6_+_146598961 Show fit	0.30	ENST00000522242.5 ENST00000397944.8	ADGB Ensembl NCBI GeneCards UniProt Show fit	androglobin
chr11_+_73272201 Show fit	0.29	ENST00000393590.3	P2RY6 Ensembl NCBI GeneCards UniProt Show fit	pyrimidinergic receptor P2Y6
chr6_+_26240385 Show fit	0.27	ENST00000244537.6	H4C6 Ensembl NCBI GeneCards UniProt Show fit	H4 clustered histone 6
chr11_+_118610374 Show fit	0.26	ENST00000532639.3	PHLDB1 Ensembl NCBI GeneCards UniProt Show fit	pleckstrin homology like domain family B member 1
chr14_+_91114431 Show fit	0.26	ENST00000428926.6 ENST00000517362.5	DGLUCY Ensembl NCBI GeneCards UniProt Show fit	D-glutamate cyclase
chr7_+_142656688 Show fit	0.26	ENST00000390397.2	TRBV24-1 Ensembl NCBI GeneCards UniProt Show fit	T cell receptor beta variable 24-1
chr2_-_135837170 Show fit	0.25	ENST00000264162.7	LCT Ensembl NCBI GeneCards UniProt Show fit	lactase
chr17_+_72121012 Show fit	0.25	ENST00000245479.3	SOX9 Ensembl NCBI GeneCards UniProt Show fit	SRY-box transcription factor 9
chr14_+_91114667 Show fit	0.25	ENST00000523894.5 ENST00000522322.5 ENST00000523771.5	DGLUCY Ensembl NCBI GeneCards UniProt Show fit	D-glutamate cyclase
chr10_-_104338431 Show fit	0.25	ENST00000647721.1 ENST00000337478.3	ITPRIP Ensembl NCBI GeneCards UniProt Show fit	inositol 1,4,5-trisphosphate receptor interacting protein
chr19_-_40690553 Show fit	0.25	ENST00000598779.5	NUMBL Ensembl NCBI GeneCards UniProt Show fit	NUMB like endocytic adaptor protein
chr7_+_139829242 Show fit	0.24	ENST00000455353.6 ENST00000458722.6 ENST00000448866.7 ENST00000411653.6	TBXAS1 Ensembl NCBI GeneCards UniProt Show fit	thromboxane A synthase 1
chr14_+_91114364 Show fit	0.23	ENST00000518868.5	DGLUCY Ensembl NCBI GeneCards UniProt Show fit	D-glutamate cyclase
chr3_+_190388120 Show fit	0.23	ENST00000456423.2 ENST00000264734.3	CLDN16 Ensembl NCBI GeneCards UniProt Show fit	claudin 16
chr1_+_66332004 Show fit	0.21	ENST00000371045.9 ENST00000531025.5 ENST00000526197.5	PDE4B Ensembl NCBI GeneCards UniProt Show fit	phosphodiesterase 4B
chr17_+_50095331 Show fit	0.21	ENST00000503176.6	PDK2 Ensembl NCBI GeneCards UniProt Show fit	pyruvate dehydrogenase kinase 2
chr16_+_649351 Show fit	0.20	ENST00000293879.9	WDR90 Ensembl NCBI GeneCards UniProt Show fit	WD repeat domain 90
chr16_+_649319 Show fit	0.19	ENST00000549091.5	WDR90 Ensembl NCBI GeneCards UniProt Show fit	WD repeat domain 90
chr6_+_25726767 Show fit	0.18	ENST00000274764.5	H2BC1 Ensembl NCBI GeneCards UniProt Show fit	H2B clustered histone 1
chr14_-_20802402 Show fit	0.17	ENST00000412779.2	RNASE1 Ensembl NCBI GeneCards UniProt Show fit	ribonuclease A family member 1, pancreatic
chr1_-_110607816 Show fit	0.17	ENST00000485317.6	KCNA2 Ensembl NCBI GeneCards UniProt Show fit	potassium voltage-gated channel subfamily A member 2
chr4_-_176195563 Show fit	0.17	ENST00000280191.7	SPATA4 Ensembl NCBI GeneCards UniProt Show fit	spermatogenesis associated 4
chr1_-_110607970 Show fit	0.17	ENST00000638532.1	KCNA2 Ensembl NCBI GeneCards UniProt Show fit	potassium voltage-gated channel subfamily A member 2
chr6_-_52577012 Show fit	0.17	ENST00000182527.4	TRAM2 Ensembl NCBI GeneCards UniProt Show fit	translocation associated membrane protein 2
chr1_+_153416517 Show fit	0.16	ENST00000368729.9	S100A7A Ensembl NCBI GeneCards UniProt Show fit	S100 calcium binding protein A7A
chr8_+_10672646 Show fit	0.16	ENST00000521818.1	C8orf74 Ensembl NCBI GeneCards UniProt Show fit	chromosome 8 open reading frame 74
chr21_-_38660656 Show fit	0.16	ENST00000398919.6	ERG Ensembl NCBI GeneCards UniProt Show fit	ETS transcription factor ERG
chr16_+_3020359 Show fit	0.16	ENST00000341627.5 ENST00000326577.9 ENST00000575124.1 ENST00000575836.1	TNFRSF12A Ensembl NCBI GeneCards UniProt Show fit	TNF receptor superfamily member 12A
chr9_+_37486006 Show fit	0.16	ENST00000377792.3	POLR1E Ensembl NCBI GeneCards UniProt Show fit	RNA polymerase I subunit E
chr6_+_26272923 Show fit	0.16	ENST00000377733.4	H2BC10 Ensembl NCBI GeneCards UniProt Show fit	H2B clustered histone 10
chr9_+_37485938 Show fit	0.15	ENST00000377798.9	POLR1E Ensembl NCBI GeneCards UniProt Show fit	RNA polymerase I subunit E
chr1_-_160862880 Show fit	0.15	ENST00000368034.9	CD244 Ensembl NCBI GeneCards UniProt Show fit	CD244 molecule
chr6_-_41921105 Show fit	0.15	ENST00000434077.1 ENST00000409312.5 ENST00000265350.9	MED20 Ensembl NCBI GeneCards UniProt Show fit	mediator complex subunit 20
chr11_+_65027402 Show fit	0.15	ENST00000377244.8 ENST00000534637.5 ENST00000524831.5	SNX15 Ensembl NCBI GeneCards UniProt Show fit	sorting nexin 15
chr3_-_112846856 Show fit	0.15	ENST00000488794.5	CD200R1L Ensembl NCBI GeneCards UniProt Show fit	CD200 receptor 1 like
chr12_+_96194365 Show fit	0.15	ENST00000228741.8 ENST00000547249.1	ELK3 Ensembl NCBI GeneCards UniProt Show fit	ETS transcription factor ELK3
chr14_-_100159595 Show fit	0.14	ENST00000553834.1 ENST00000305631.7	DEGS2 Ensembl NCBI GeneCards UniProt Show fit	delta 4-desaturase, sphingolipid 2
chr1_+_206865620 Show fit	0.14	ENST00000367098.6	IL20 Ensembl NCBI GeneCards UniProt Show fit	interleukin 20
chrX_+_49829260 Show fit	0.14	ENST00000376141.5 ENST00000218068.7	PAGE4 Ensembl NCBI GeneCards UniProt Show fit	PAGE family member 4
chr9_+_128420812 Show fit	0.14	ENST00000372838.9	CERCAM Ensembl NCBI GeneCards UniProt Show fit	cerebral endothelial cell adhesion molecule
chr19_-_45645560 Show fit	0.14	ENST00000587152.6	EML2 Ensembl NCBI GeneCards UniProt Show fit	EMAP like 2
chr1_+_173824694 Show fit	0.14	ENST00000647645.1	DARS2 Ensembl NCBI GeneCards UniProt Show fit	aspartyl-tRNA synthetase 2, mitochondrial
chr1_+_202416826 Show fit	0.14	ENST00000466968.1	PPP1R12B Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 1 regulatory subunit 12B
chr7_+_31514084 Show fit	0.14	ENST00000409717.5 ENST00000456011.5 ENST00000615280.5	ITPRID1 Ensembl NCBI GeneCards UniProt Show fit	ITPR interacting domain containing 1
chr17_-_3292600 Show fit	0.13	ENST00000615105.1	OR3A1 Ensembl NCBI GeneCards UniProt Show fit	olfactory receptor family 3 subfamily A member 1
chr6_-_11807045 Show fit	0.13	ENST00000379415.6	ADTRP Ensembl NCBI GeneCards UniProt Show fit	androgen dependent TFPI regulating protein
chr2_-_79086847 Show fit	0.13	ENST00000454188.5	REG1B Ensembl NCBI GeneCards UniProt Show fit	regenerating family member 1 beta
chr17_+_38297023 Show fit	0.13	ENST00000619548.1 ENST00000613675.5	MRPL45 Ensembl NCBI GeneCards UniProt Show fit	mitochondrial ribosomal protein L45
chr4_-_147684114 Show fit	0.13	ENST00000322396.7	PRMT9 Ensembl NCBI GeneCards UniProt Show fit	protein arginine methyltransferase 9
chr19_-_11577632 Show fit	0.13	ENST00000590420.1 ENST00000648477.1	ACP5 Ensembl NCBI GeneCards UniProt Show fit	acid phosphatase 5, tartrate resistant
chrX_+_50067576 Show fit	0.13	ENST00000376108.7	CLCN5 Ensembl NCBI GeneCards UniProt Show fit	chloride voltage-gated channel 5
chr22_+_41560973 Show fit	0.13	ENST00000306149.12	CSDC2 Ensembl NCBI GeneCards UniProt Show fit	cold shock domain containing C2
chr15_-_70763430 Show fit	0.13	ENST00000539319.5	UACA Ensembl NCBI GeneCards UniProt Show fit	uveal autoantigen with coiled-coil domains and ankyrin repeats
chr15_-_28712323 Show fit	0.13	ENST00000563027.1	GOLGA8M Ensembl NCBI GeneCards UniProt Show fit	golgin A8 family member M
chr6_-_27807916 Show fit	0.13	ENST00000377401.3	H2BC13 Ensembl NCBI GeneCards UniProt Show fit	H2B clustered histone 13
chr17_-_18682262 Show fit	0.13	ENST00000454745.2 ENST00000395675.7	FOXO3B Ensembl NCBI GeneCards UniProt Show fit	forkhead box O3B
chr3_+_102435015 Show fit	0.13	ENST00000306176.5 ENST00000466937.2	ZPLD1 Ensembl NCBI GeneCards UniProt Show fit	zona pellucida like domain containing 1
chr7_-_22822779 Show fit	0.12	ENST00000372879.8	TOMM7 Ensembl NCBI GeneCards UniProt Show fit	translocase of outer mitochondrial membrane 7
chr6_+_27815010 Show fit	0.12	ENST00000621112.2	H2BC14 Ensembl NCBI GeneCards UniProt Show fit	H2B clustered histone 14
chr6_-_41921081 Show fit	0.12	ENST00000409060.1	MED20 Ensembl NCBI GeneCards UniProt Show fit	mediator complex subunit 20
chr1_+_173824626 Show fit	0.12	ENST00000648960.1 ENST00000648807.1 ENST00000649067.1 ENST00000649689.2	DARS2 Ensembl NCBI GeneCards UniProt Show fit	aspartyl-tRNA synthetase 2, mitochondrial
chr7_-_22822829 Show fit	0.12	ENST00000358435.9 ENST00000621567.1	TOMM7 Ensembl NCBI GeneCards UniProt Show fit	translocase of outer mitochondrial membrane 7
chr1_-_60073750 Show fit	0.12	ENST00000371201.3	C1orf87 Ensembl NCBI GeneCards UniProt Show fit	chromosome 1 open reading frame 87
chr16_+_30472700 Show fit	0.11	ENST00000358164.9	ITGAL Ensembl NCBI GeneCards UniProt Show fit	integrin subunit alpha L
chr1_-_60073733 Show fit	0.11	ENST00000450089.6	C1orf87 Ensembl NCBI GeneCards UniProt Show fit	chromosome 1 open reading frame 87
chr1_-_9069608 Show fit	0.11	ENST00000377424.9	SLC2A5 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 2 member 5
chr15_+_65530418 Show fit	0.11	ENST00000562901.5 ENST00000261875.10 ENST00000442729.6 ENST00000565299.5 ENST00000568793.5	HACD3 Ensembl NCBI GeneCards UniProt Show fit	3-hydroxyacyl-CoA dehydratase 3
chr1_-_225923891 Show fit	0.11	ENST00000472798.2 ENST00000489681.5 ENST00000612651.4	PYCR2 Ensembl NCBI GeneCards UniProt Show fit	pyrroline-5-carboxylate reductase 2
chr7_-_14903319 Show fit	0.11	ENST00000403951.6	DGKB Ensembl NCBI GeneCards UniProt Show fit	diacylglycerol kinase beta
chr6_-_27132750 Show fit	0.11	ENST00000607124.1 ENST00000339812.3	H2BC11 Ensembl NCBI GeneCards UniProt Show fit	H2B clustered histone 11
chr3_+_125969172 Show fit	0.10	ENST00000514116.6 ENST00000513830.5	ROPN1B Ensembl NCBI GeneCards UniProt Show fit	rhophilin associated tail protein 1B
chr15_-_82709823 Show fit	0.10	ENST00000666973.1 ENST00000664460.1 ENST00000669930.1	AP3B2 Ensembl NCBI GeneCards UniProt Show fit	adaptor related protein complex 3 subunit beta 2
chr2_+_96325294 Show fit	0.10	ENST00000439118.3 ENST00000420176.5 ENST00000536814.1	ITPRIPL1 Ensembl NCBI GeneCards UniProt Show fit	ITPRIP like 1
chr3_-_123992046 Show fit	0.10	ENST00000467907.5 ENST00000459660.5 ENST00000495093.1 ENST00000460743.5 ENST00000405845.7 ENST00000484329.1 ENST00000479867.1 ENST00000496145.5	ROPN1 Ensembl NCBI GeneCards UniProt Show fit	rhophilin associated tail protein 1
chr6_-_26285526 Show fit	0.10	ENST00000377727.2	H4C8 Ensembl NCBI GeneCards UniProt Show fit	H4 clustered histone 8
chr14_-_24081928 Show fit	0.10	ENST00000396995.1	NRL Ensembl NCBI GeneCards UniProt Show fit	neural retina leucine zipper
chr21_+_44133610 Show fit	0.10	ENST00000644251.1 ENST00000427803.6 ENST00000348499.9 ENST00000291577.11 ENST00000389690.7	GATD3A Ensembl NCBI GeneCards UniProt Show fit	glutamine amidotransferase like class 1 domain containing 3A
chr7_-_19773569 Show fit	0.09	ENST00000422233.5 ENST00000433641.5 ENST00000405844.6	TMEM196 Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 196
chr2_+_219245455 Show fit	0.09	ENST00000409638.7 ENST00000396738.7 ENST00000409516.7	STK16 Ensembl NCBI GeneCards UniProt Show fit	serine/threonine kinase 16
chr15_-_82709775 Show fit	0.09	ENST00000535348.5	AP3B2 Ensembl NCBI GeneCards UniProt Show fit	adaptor related protein complex 3 subunit beta 2
chr22_+_22747383 Show fit	0.09	ENST00000390311.3	IGLV3-16 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin lambda variable 3-16
chr3_-_52897541 Show fit	0.09	ENST00000355083.11 ENST00000504329.1	STIMATE Ensembl NCBI GeneCards UniProt Show fit STIMATE-MUSTN1 Ensembl NCBI GeneCards UniProt Show fit	STIM activating enhancer STIMATE-MUSTN1 readthrough
chr11_+_117199363 Show fit	0.09	ENST00000392951.9 ENST00000525531.5 ENST00000278968.10	TAGLN Ensembl NCBI GeneCards UniProt Show fit	transgelin
chr17_-_40937445 Show fit	0.09	ENST00000436344.7 ENST00000485751.1	KRT23 Ensembl NCBI GeneCards UniProt Show fit	keratin 23
chr16_+_30472733 Show fit	0.09	ENST00000356798.11 ENST00000433423.2	ITGAL Ensembl NCBI GeneCards UniProt Show fit	integrin subunit alpha L
chr1_+_59296971 Show fit	0.09	ENST00000371218.8	FGGY Ensembl NCBI GeneCards UniProt Show fit	FGGY carbohydrate kinase domain containing
chr3_+_98149326 Show fit	0.09	ENST00000437310.1	OR5H14 Ensembl NCBI GeneCards UniProt Show fit	olfactory receptor family 5 subfamily H member 14
chr14_+_91114026 Show fit	0.08	ENST00000521081.5 ENST00000520328.5 ENST00000524232.5 ENST00000522170.5 ENST00000256324.15 ENST00000519950.5 ENST00000523879.5 ENST00000521077.6 ENST00000518665.6	DGLUCY Ensembl NCBI GeneCards UniProt Show fit	D-glutamate cyclase
chr17_+_4710622 Show fit	0.08	ENST00000574954.5 ENST00000269260.7 ENST00000346341.6 ENST00000572457.5 ENST00000381488.10 ENST00000412477.7 ENST00000571428.5 ENST00000575877.5	ARRB2 Ensembl NCBI GeneCards UniProt Show fit	arrestin beta 2
chr5_-_69332723 Show fit	0.08	ENST00000511257.1 ENST00000396496.7 ENST00000383374.6	CCDC125 Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 125
chr6_+_30882914 Show fit	0.08	ENST00000509639.5 ENST00000412274.6 ENST00000507901.5 ENST00000507046.5 ENST00000437124.6 ENST00000454612.6 ENST00000396342.6	DDR1 Ensembl NCBI GeneCards UniProt Show fit	discoidin domain receptor tyrosine kinase 1
chr1_+_59297057 Show fit	0.08	ENST00000303721.12	FGGY Ensembl NCBI GeneCards UniProt Show fit	FGGY carbohydrate kinase domain containing
chr11_-_34916310 Show fit	0.08	ENST00000395787.4	APIP Ensembl NCBI GeneCards UniProt Show fit	APAF1 interacting protein
chrX_-_49233309 Show fit	0.08	ENST00000376251.5 ENST00000323022.10 ENST00000376265.2	CACNA1F Ensembl NCBI GeneCards UniProt Show fit	calcium voltage-gated channel subunit alpha1 F
chr6_+_27893411 Show fit	0.08	ENST00000616182.2	H2BC17 Ensembl NCBI GeneCards UniProt Show fit	H2B clustered histone 17
chr15_+_51341648 Show fit	0.08	ENST00000335449.11 ENST00000560215.5	GLDN Ensembl NCBI GeneCards UniProt Show fit	gliomedin
chr14_-_24081986 Show fit	0.08	ENST00000560550.1	NRL Ensembl NCBI GeneCards UniProt Show fit	neural retina leucine zipper
chr6_-_26027274 Show fit	0.08	ENST00000377745.4	H4C2 Ensembl NCBI GeneCards UniProt Show fit	H4 clustered histone 2
chr1_+_201190786 Show fit	0.08	ENST00000335211.9 ENST00000295591.12	IGFN1 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin like and fibronectin type III domain containing 1
chr20_-_31723491 Show fit	0.08	ENST00000676582.1 ENST00000422920.2	BCL2L1 Ensembl NCBI GeneCards UniProt Show fit	BCL2 like 1
chr6_+_27838600 Show fit	0.08	ENST00000606613.1	H2BC15 Ensembl NCBI GeneCards UniProt Show fit	H2B clustered histone 15
chr6_-_99394164 Show fit	0.08	ENST00000254759.8	COQ3 Ensembl NCBI GeneCards UniProt Show fit	coenzyme Q3, methyltransferase
chr18_+_13612614 Show fit	0.08	ENST00000586765.1 ENST00000677910.1	LDLRAD4 Ensembl NCBI GeneCards UniProt Show fit	low density lipoprotein receptor class A domain containing 4
chr6_-_27873525 Show fit	0.08	ENST00000618305.2	H4C13 Ensembl NCBI GeneCards UniProt Show fit	H4 clustered histone 13
chr2_-_217944005 Show fit	0.08	ENST00000611415.4 ENST00000615025.5 ENST00000449814.1 ENST00000171887.8	TNS1 Ensembl NCBI GeneCards UniProt Show fit	tensin 1
chr12_+_119178920 Show fit	0.08	ENST00000281938.7	HSPB8 Ensembl NCBI GeneCards UniProt Show fit	heat shock protein family B (small) member 8
chr20_-_63463843 Show fit	0.07	ENST00000637193.1	KCNQ2 Ensembl NCBI GeneCards UniProt Show fit	potassium voltage-gated channel subfamily Q member 2
chr8_+_10672623 Show fit	0.07	ENST00000304519.10	C8orf74 Ensembl NCBI GeneCards UniProt Show fit	chromosome 8 open reading frame 74
chr14_-_105987068 Show fit	0.07	ENST00000390594.3	IGHV1-2 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin heavy variable 1-2
chr20_-_31723902 Show fit	0.07	ENST00000676942.1 ENST00000450273.2 ENST00000678563.1 ENST00000456404.6 ENST00000420488.6 ENST00000439267.2	BCL2L1 Ensembl NCBI GeneCards UniProt Show fit	BCL2 like 1
chr2_-_128028010 Show fit	0.07	ENST00000643581.2 ENST00000450957.1	SAP130 Ensembl NCBI GeneCards UniProt Show fit	Sin3A associated protein 130
chr5_+_132873660 Show fit	0.07	ENST00000296877.3	LEAP2 Ensembl NCBI GeneCards UniProt Show fit	liver enriched antimicrobial peptide 2
chr6_-_27146841 Show fit	0.07	ENST00000356950.2	H2BC12 Ensembl NCBI GeneCards UniProt Show fit	H2B clustered histone 12
chr2_-_128028114 Show fit	0.07	ENST00000259234.10	SAP130 Ensembl NCBI GeneCards UniProt Show fit	Sin3A associated protein 130
chr19_-_37467185 Show fit	0.07	ENST00000592490.5 ENST00000392149.6	ZNF569 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 569
chr6_-_27838362 Show fit	0.07	ENST00000618958.2	H2AC15 Ensembl NCBI GeneCards UniProt Show fit	H2A clustered histone 15
chr12_+_119178953 Show fit	0.07	ENST00000674542.1	HSPB8 Ensembl NCBI GeneCards UniProt Show fit	heat shock protein family B (small) member 8
chr21_+_31659666 Show fit	0.07	ENST00000389995.4 ENST00000270142.11	SOD1 Ensembl NCBI GeneCards UniProt Show fit	superoxide dismutase 1
chr7_+_142384328 Show fit	0.07	ENST00000390361.3	TRBV7-3 Ensembl NCBI GeneCards UniProt Show fit	T cell receptor beta variable 7-3
chr20_+_59676661 Show fit	0.07	ENST00000355648.8	PHACTR3 Ensembl NCBI GeneCards UniProt Show fit	phosphatase and actin regulator 3
chr6_-_132798587 Show fit	0.07	ENST00000275227.9	SLC18B1 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 18 member B1
chr6_+_41921491 Show fit	0.06	ENST00000230340.9	BYSL Ensembl NCBI GeneCards UniProt Show fit	bystin like
chr1_-_110607307 Show fit	0.06	ENST00000639048.2 ENST00000675391.1 ENST00000639233.2	KCNA2 Ensembl NCBI GeneCards UniProt Show fit	potassium voltage-gated channel subfamily A member 2
chr9_+_5890872 Show fit	0.06	ENST00000381477.8 ENST00000381476.5 ENST00000381471.1	MLANA Ensembl NCBI GeneCards UniProt Show fit	melan-A
chr15_+_63504583 Show fit	0.06	ENST00000380324.8 ENST00000561442.5 ENST00000560070.5	USP3 Ensembl NCBI GeneCards UniProt Show fit	ubiquitin specific peptidase 3
chr6_-_27814757 Show fit	0.06	ENST00000333151.5	H2AC14 Ensembl NCBI GeneCards UniProt Show fit	H2A clustered histone 14
chr1_-_110607425 Show fit	0.06	ENST00000633222.1	KCNA2 Ensembl NCBI GeneCards UniProt Show fit	potassium voltage-gated channel subfamily A member 2
chr6_-_26189101 Show fit	0.06	ENST00000614247.2	H4C4 Ensembl NCBI GeneCards UniProt Show fit	H4 clustered histone 4
chr9_+_133534807 Show fit	0.06	ENST00000393060.1	ADAMTSL2 Ensembl NCBI GeneCards UniProt Show fit	ADAMTS like 2
chr11_-_133532493 Show fit	0.06	ENST00000524381.6	OPCML Ensembl NCBI GeneCards UniProt Show fit	opioid binding protein/cell adhesion molecule like
chrX_+_47585212 Show fit	0.06	ENST00000445623.1	TIMP1 Ensembl NCBI GeneCards UniProt Show fit	TIMP metallopeptidase inhibitor 1
chr15_+_63504511 Show fit	0.06	ENST00000540797.5	USP3 Ensembl NCBI GeneCards UniProt Show fit	ubiquitin specific peptidase 3
chr22_-_35617321 Show fit	0.06	ENST00000397326.7 ENST00000442617.1	MB Ensembl NCBI GeneCards UniProt Show fit	myoglobin
chr18_+_46946821 Show fit	0.06	ENST00000245121.9 ENST00000356157.12	KATNAL2 Ensembl NCBI GeneCards UniProt Show fit	katanin catalytic subunit A1 like 2
chr12_+_49741565 Show fit	0.06	ENST00000549445.5 ENST00000550951.5 ENST00000549385.5 ENST00000548713.5 ENST00000548201.5	TMBIM6 Ensembl NCBI GeneCards UniProt Show fit	transmembrane BAX inhibitor motif containing 6
chr16_-_20669855 Show fit	0.05	ENST00000524149.5	ACSM1 Ensembl NCBI GeneCards UniProt Show fit	acyl-CoA synthetase medium chain family member 1
chr11_-_64744993 Show fit	0.05	ENST00000377485.5	RASGRP2 Ensembl NCBI GeneCards UniProt Show fit	RAS guanyl releasing protein 2
chrX_-_102155790 Show fit	0.05	ENST00000543160.5 ENST00000333643.4	BEX5 Ensembl NCBI GeneCards UniProt Show fit	brain expressed X-linked 5
chr15_-_82709859 Show fit	0.05	ENST00000542200.2 ENST00000535359.6 ENST00000668990.2 ENST00000652847.1	AP3B2 Ensembl NCBI GeneCards UniProt Show fit	adaptor related protein complex 3 subunit beta 2
chr9_+_133534697 Show fit	0.05	ENST00000651351.2	ADAMTSL2 Ensembl NCBI GeneCards UniProt Show fit	ADAMTS like 2
chr12_+_49741544 Show fit	0.05	ENST00000549966.5 ENST00000547832.5 ENST00000547187.5 ENST00000548894.5 ENST00000546914.5 ENST00000552699.5 ENST00000267115.10	TMBIM6 Ensembl NCBI GeneCards UniProt Show fit	transmembrane BAX inhibitor motif containing 6
chr18_+_32018817 Show fit	0.05	ENST00000217740.4 ENST00000583184.1	RNF125 Ensembl NCBI GeneCards UniProt Show fit ENSG00000263917.1 Ensembl NCBI GeneCards UniProt Show fit	ring finger protein 125 novel transcript
chr8_-_80029826 Show fit	0.05	ENST00000519386.5	MRPS28 Ensembl NCBI GeneCards UniProt Show fit	mitochondrial ribosomal protein S28
chr19_+_51225059 Show fit	0.05	ENST00000436584.6 ENST00000421133.6 ENST00000262262.5 ENST00000391796.7	CD33 Ensembl NCBI GeneCards UniProt Show fit	CD33 molecule
chr12_-_110468222 Show fit	0.05	ENST00000228827.8 ENST00000537466.6 ENST00000550974.1	GPN3 Ensembl NCBI GeneCards UniProt Show fit	GPN-loop GTPase 3
chr5_+_140450 Show fit	0.04	ENST00000502646.1	PLEKHG4B Ensembl NCBI GeneCards UniProt Show fit	pleckstrin homology and RhoGEF domain containing G4B
chr15_-_43493076 Show fit	0.04	ENST00000413546.1	TP53BP1 Ensembl NCBI GeneCards UniProt Show fit	tumor protein p53 binding protein 1
chr8_-_80029904 Show fit	0.04	ENST00000521434.5 ENST00000519120.1 ENST00000520946.1	MRPS28 Ensembl NCBI GeneCards UniProt Show fit	mitochondrial ribosomal protein S28
chr12_+_49741802 Show fit	0.04	ENST00000423828.5 ENST00000550445.5	TMBIM6 Ensembl NCBI GeneCards UniProt Show fit	transmembrane BAX inhibitor motif containing 6
chr5_-_128339191 Show fit	0.04	ENST00000507835.5	FBN2 Ensembl NCBI GeneCards UniProt Show fit	fibrillin 2
chr11_+_57763820 Show fit	0.04	ENST00000674106.1	CTNND1 Ensembl NCBI GeneCards UniProt Show fit	catenin delta 1
chr6_-_65707214 Show fit	0.04	ENST00000370621.7 ENST00000393380.6 ENST00000503581.6	EYS Ensembl NCBI GeneCards UniProt Show fit	eyes shut homolog
chr3_+_125969152 Show fit	0.04	ENST00000251776.8 ENST00000504401.1	ROPN1B Ensembl NCBI GeneCards UniProt Show fit	rhophilin associated tail protein 1B
chr10_+_28677487 Show fit	0.04	ENST00000375533.6	BAMBI Ensembl NCBI GeneCards UniProt Show fit	BMP and activin membrane bound inhibitor
chr18_+_13611764 Show fit	0.04	ENST00000585931.5	LDLRAD4 Ensembl NCBI GeneCards UniProt Show fit	low density lipoprotein receptor class A domain containing 4
chr1_-_20787287 Show fit	0.04	ENST00000438032.6 ENST00000424732.5 ENST00000437575.5	HP1BP3 Ensembl NCBI GeneCards UniProt Show fit	heterochromatin protein 1 binding protein 3
chr15_-_82709886 Show fit	0.04	ENST00000666055.1 ENST00000261722.8 ENST00000535513.2	AP3B2 Ensembl NCBI GeneCards UniProt Show fit	adaptor related protein complex 3 subunit beta 2
chr15_-_60397964 Show fit	0.04	ENST00000558998.5 ENST00000560165.5 ENST00000557986.5 ENST00000559467.5 ENST00000677968.1 ENST00000678450.1 ENST00000332680.8 ENST00000396024.7 ENST00000557906.6 ENST00000558558.6 ENST00000559113.6 ENST00000559780.6 ENST00000559956.6 ENST00000560468.6 ENST00000678870.1 ENST00000678061.1 ENST00000451270.7 ENST00000421017.6 ENST00000560466.5 ENST00000558132.5 ENST00000559370.5 ENST00000559725.5 ENST00000558985.6 ENST00000679109.1	ANXA2 Ensembl NCBI GeneCards UniProt Show fit	annexin A2
chr1_-_88891496 Show fit	0.03	ENST00000448623.5 ENST00000370500.10 ENST00000418217.1	GTF2B Ensembl NCBI GeneCards UniProt Show fit	general transcription factor IIB
chr2_-_157628852 Show fit	0.03	ENST00000243349.13	ACVR1C Ensembl NCBI GeneCards UniProt Show fit	activin A receptor type 1C
chr5_+_141245384 Show fit	0.03	ENST00000623671.1 ENST00000231173.6	PCDHB15 Ensembl NCBI GeneCards UniProt Show fit	protocadherin beta 15
chr18_+_13218195 Show fit	0.03	ENST00000679167.1	LDLRAD4 Ensembl NCBI GeneCards UniProt Show fit	low density lipoprotein receptor class A domain containing 4
chr2_+_203867943 Show fit	0.03	ENST00000295854.10 ENST00000487393.1 ENST00000472206.1	CTLA4 Ensembl NCBI GeneCards UniProt Show fit	cytotoxic T-lymphocyte associated protein 4
chr7_+_31687208 Show fit	0.03	ENST00000409146.3 ENST00000342032.8	PPP1R17 Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 1 regulatory subunit 17
chr14_+_24130659 Show fit	0.03	ENST00000267426.6	FITM1 Ensembl NCBI GeneCards UniProt Show fit	fat storage inducing transmembrane protein 1
chr11_+_116829898 Show fit	0.03	ENST00000227667.8 ENST00000375345.3	APOC3 Ensembl NCBI GeneCards UniProt Show fit	apolipoprotein C3
chr1_-_8817633 Show fit	0.03	ENST00000400908.7	RERE Ensembl NCBI GeneCards UniProt Show fit	arginine-glutamic acid dipeptide repeats
chr11_-_61333784 Show fit	0.03	ENST00000680367.1 ENST00000681803.1	DDB1 Ensembl NCBI GeneCards UniProt Show fit	damage specific DNA binding protein 1
chr3_+_14178808 Show fit	0.03	ENST00000306024.4	LSM3 Ensembl NCBI GeneCards UniProt Show fit	LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated
chr14_+_21868822 Show fit	0.03	ENST00000390436.2	TRAV13-1 Ensembl NCBI GeneCards UniProt Show fit	T cell receptor alpha variable 13-1
chr7_+_100720463 Show fit	0.03	ENST00000252723.3	EPO Ensembl NCBI GeneCards UniProt Show fit	erythropoietin
chr2_-_24793382 Show fit	0.02	ENST00000328379.6	PTRHD1 Ensembl NCBI GeneCards UniProt Show fit	peptidyl-tRNA hydrolase domain containing 1
chr9_-_34637719 Show fit	0.02	ENST00000378892.5 ENST00000680277.1 ENST00000277010.9 ENST00000679597.1 ENST00000680244.1	SIGMAR1 Ensembl NCBI GeneCards UniProt Show fit	sigma non-opioid intracellular receptor 1
chr9_-_34691204 Show fit	0.02	ENST00000378800.3 ENST00000311925.7	CCL19 Ensembl NCBI GeneCards UniProt Show fit	C-C motif chemokine ligand 19
chr5_+_55851349 Show fit	0.02	ENST00000652347.2	IL31RA Ensembl NCBI GeneCards UniProt Show fit	interleukin 31 receptor A
chr5_+_55851378 Show fit	0.02	ENST00000396836.6 ENST00000359040.10	IL31RA Ensembl NCBI GeneCards UniProt Show fit	interleukin 31 receptor A
chr17_-_35868885 Show fit	0.02	ENST00000604834.6	HEATR9 Ensembl NCBI GeneCards UniProt Show fit	HEAT repeat containing 9
chr14_+_91114388 Show fit	0.02	ENST00000519019.5 ENST00000523816.5 ENST00000517518.5	DGLUCY Ensembl NCBI GeneCards UniProt Show fit	D-glutamate cyclase
chr5_+_168486462 Show fit	0.02	ENST00000231572.8 ENST00000626454.1	RARS1 Ensembl NCBI GeneCards UniProt Show fit	arginyl-tRNA synthetase 1
chr6_+_122717544 Show fit	0.02	ENST00000354275.2 ENST00000368446.1	PKIB Ensembl NCBI GeneCards UniProt Show fit	cAMP-dependent protein kinase inhibitor beta
chr9_-_34637800 Show fit	0.02	ENST00000680730.1 ENST00000477726.1	SIGMAR1 Ensembl NCBI GeneCards UniProt Show fit	sigma non-opioid intracellular receptor 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0038162	erythropoietin-mediated signaling pathway(GO:0038162)
0.1	0.3	GO:0001300	chronological cell aging(GO:0001300)
0.1	0.3	GO:0001189	RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
0.1	0.5	GO:0090131	glomerular mesangial cell development(GO:0072144) mesenchyme migration(GO:0090131)
0.1	0.3	GO:0006421	asparaginyl-tRNA aminoacylation(GO:0006421)
0.1	0.3	GO:0060516	primary prostatic bud elongation(GO:0060516) renal vesicle induction(GO:0072034)
0.1	0.2	GO:0021849	neuroblast division in subventricular zone(GO:0021849)
0.1	0.8	GO:0051918	negative regulation of fibrinolysis(GO:0051918)
0.1	0.4	GO:1903282	negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.1	0.2	GO:2000566	positive regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000566)
0.1	0.3	GO:1900226	negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.0	0.1	GO:0006667	sphinganine metabolic process(GO:0006667)
0.0	0.5	GO:0021633	optic nerve structural organization(GO:0021633)
0.0	0.4	GO:0010265	SCF complex assembly(GO:0010265)
0.0	0.3	GO:0044245	polysaccharide digestion(GO:0044245)
0.0	0.2	GO:0045872	positive regulation of rhodopsin gene expression(GO:0045872)
0.0	0.2	GO:0045048	protein insertion into ER membrane(GO:0045048)
0.0	0.2	GO:2000504	positive regulation of blood vessel remodeling(GO:2000504)
0.0	0.3	GO:2000795	negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0	1.1	GO:0061049	physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0	0.2	GO:0045040	protein import into mitochondrial outer membrane(GO:0045040)
0.0	0.1	GO:0032929	negative regulation of superoxide anion generation(GO:0032929)
0.0	0.7	GO:0007342	fusion of sperm to egg plasma membrane(GO:0007342)
0.0	0.1	GO:1904721	negative regulation of mRNA cleavage(GO:0031438) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.0	0.3	GO:0030321	transepithelial chloride transport(GO:0030321)
0.0	0.2	GO:0006931	substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0	0.1	GO:0019918	peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.0	0.1	GO:0034392	desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032) negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.0	0.2	GO:0060154	cellular process regulating host cell cycle in response to virus(GO:0060154)
0.0	0.1	GO:0018874	benzoate metabolic process(GO:0018874)
0.0	0.1	GO:0046726	positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0	0.2	GO:1901898	negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0	0.1	GO:0060481	lobar bronchus epithelium development(GO:0060481)
0.0	0.0	GO:1990022	RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.0	0.5	GO:0006833	water transport(GO:0006833)
0.0	0.3	GO:1904261	regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.0	0.1	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0	0.1	GO:0055129	L-proline biosynthetic process(GO:0055129)
0.0	0.1	GO:0010968	regulation of microtubule nucleation(GO:0010968)
0.0	0.2	GO:0002291	T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
0.0	0.2	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.0	0.2	GO:0050812	regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0	0.2	GO:0019371	cyclooxygenase pathway(GO:0019371)
0.0	0.0	GO:0060621	regulation of high-density lipoprotein particle clearance(GO:0010982) negative regulation of cholesterol import(GO:0060621) negative regulation of sterol import(GO:2000910)
0.0	0.2	GO:1903830	magnesium ion transmembrane transport(GO:1903830)
0.0	0.1	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.0	0.1	GO:0045590	negative regulation of regulatory T cell differentiation(GO:0045590)
0.0	0.4	GO:0010842	retina layer formation(GO:0010842)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0072563	endothelial microparticle(GO:0072563)
0.1	0.5	GO:0030485	smooth muscle contractile fiber(GO:0030485)
0.0	0.2	GO:0005967	mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0	0.5	GO:0033010	paranodal junction(GO:0033010)
0.0	0.8	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.0	0.2	GO:0034687	integrin alphaL-beta2 complex(GO:0034687)
0.0	0.2	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742)
0.0	0.3	GO:0030123	AP-3 adaptor complex(GO:0030123)
0.0	0.3	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.0	0.3	GO:0045180	basal cortex(GO:0045180)
0.0	0.3	GO:0044300	cerebellar mossy fiber(GO:0044300)
0.0	0.0	GO:1990667	PCSK9-AnxA2 complex(GO:1990667)
0.0	0.2	GO:0097136	Bcl-2 family protein complex(GO:0097136)
0.0	0.4	GO:0031092	platelet alpha granule membrane(GO:0031092)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0036134	thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.1	0.4	GO:0060961	phospholipase D inhibitor activity(GO:0060961)
0.1	0.6	GO:0004565	beta-galactosidase activity(GO:0004565)
0.1	0.2	GO:0019150	D-ribulokinase activity(GO:0019150)
0.1	0.3	GO:0008422	beta-glucosidase activity(GO:0008422)
0.0	0.3	GO:0045029	UDP-activated nucleotide receptor activity(GO:0045029)
0.0	0.1	GO:0042284	sphingolipid delta-4 desaturase activity(GO:0042284)
0.0	0.3	GO:0005534	galactose binding(GO:0005534)
0.0	0.1	GO:0032422	purine-rich negative regulatory element binding(GO:0032422)
0.0	1.1	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.2	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0	0.2	GO:0004522	ribonuclease A activity(GO:0004522)
0.0	0.5	GO:0015250	water channel activity(GO:0015250)
0.0	0.1	GO:0050436	microfibril binding(GO:0050436)
0.0	0.1	GO:0035243	protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.0	0.1	GO:0060698	endoribonuclease inhibitor activity(GO:0060698)
0.0	0.1	GO:0031826	type 2A serotonin receptor binding(GO:0031826)
0.0	0.5	GO:0015271	outward rectifier potassium channel activity(GO:0015271)
0.0	0.2	GO:0030369	ICAM-3 receptor activity(GO:0030369)
0.0	0.3	GO:0097157	pre-mRNA intronic binding(GO:0097157)
0.0	0.1	GO:0008169	C-methyltransferase activity(GO:0008169)
0.0	0.3	GO:0004716	receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0	0.2	GO:0015266	protein channel activity(GO:0015266)
0.0	0.3	GO:0001054	RNA polymerase I activity(GO:0001054)
0.0	0.1	GO:0102344	3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.0	0.4	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.0	0.1	GO:0004735	pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0	0.7	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.0	0.1	GO:0038062	protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0	0.2	GO:0051434	BH3 domain binding(GO:0051434)
0.0	0.2	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.0	0.2	GO:0043522	leucine zipper domain binding(GO:0043522)
0.0	0.4	GO:0017025	TBP-class protein binding(GO:0017025)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.8	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Total log-likelihood	Term	Description
0.8	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.5	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.3	REACTOME DIGESTION OF DIETARY CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate
0.3	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.3	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.2	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.3	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.3	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.2	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.4	REACTOME AMYLOIDS	Genes involved in Amyloids

Results for SMAD3

Z-value: 0.58

Motif logo

Transcription factors associated with SMAD3

Activity-expression correlation:

Activity profile of SMAD3 motif

Sorted Z-values of SMAD3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of SMAD3

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Top targets:

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: