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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for SMAD4

Z-value: 1.07

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Transcription factors associated with SMAD4

Gene Symbol Gene ID Gene Info
ENSG00000141646.14 SMAD4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SMAD4hg38_v1_chr18_+_51030100_51030270-0.291.6e-01Click!

Activity profile of SMAD4 motif

Sorted Z-values of SMAD4 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of SMAD4

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr1_+_99646025 4.03 ENST00000263174.9
ENST00000605497.5
ENST00000615664.1
palmdelphin
chr4_+_155667096 1.98 ENST00000393832.7
guanylate cyclase 1 soluble subunit alpha 1
chr4_+_155667198 1.98 ENST00000296518.11
guanylate cyclase 1 soluble subunit alpha 1
chr4_+_155666963 1.98 ENST00000455639.6
guanylate cyclase 1 soluble subunit alpha 1
chr20_+_32010429 1.65 ENST00000452892.3
ENST00000262659.12
CCM2 like scaffold protein
chr4_+_155666827 1.60 ENST00000511507.5
ENST00000506455.6
guanylate cyclase 1 soluble subunit alpha 1
chr4_+_54657918 1.54 ENST00000412167.6
ENST00000288135.6
KIT proto-oncogene, receptor tyrosine kinase
chr9_-_14321948 1.53 ENST00000635877.1
ENST00000636432.1
ENST00000646622.1
nuclear factor I B
chr1_+_61404076 1.52 ENST00000357977.5
nuclear factor I A
chr17_+_63484840 1.50 ENST00000290863.10
ENST00000413513.7
angiotensin I converting enzyme
chr5_-_88731827 1.50 ENST00000627170.2
myocyte enhancer factor 2C
chr12_+_53050179 1.29 ENST00000546602.5
ENST00000552570.5
ENST00000549700.5
tensin 2
chr11_+_43942627 1.27 ENST00000617612.3
chromosome 11 open reading frame 96
chr19_-_18941117 1.25 ENST00000600077.5
homer scaffold protein 3
chr4_-_185775890 1.24 ENST00000437304.6
sorbin and SH3 domain containing 2
chr12_-_9760893 1.21 ENST00000228434.7
ENST00000536709.1
CD69 molecule
chrX_-_63351308 1.20 ENST00000374884.3
spindlin family member 4
chr11_+_59755427 1.14 ENST00000529177.5
syntaxin 3
chr15_+_57376497 1.14 ENST00000281282.6
cingulin like 1
chr10_+_73911104 1.07 ENST00000446342.5
ENST00000372764.4
plasminogen activator, urokinase
chr17_+_34270213 1.04 ENST00000378569.2
ENST00000394627.5
ENST00000394630.3
C-C motif chemokine ligand 7
chr3_+_126524319 1.04 ENST00000615522.1
carbohydrate sulfotransferase 13
chr9_-_14322320 1.03 ENST00000606230.2
nuclear factor I B
chr14_+_64214136 1.03 ENST00000557084.1
ENST00000458046.6
spectrin repeat containing nuclear envelope protein 2
chr2_-_55296361 0.99 ENST00000647547.1
coiled-coil domain containing 88A
chr22_+_22594528 0.97 ENST00000390303.3
immunoglobulin lambda variable 3-32 (non-functional)
chr11_-_33892010 0.96 ENST00000257818.3
LIM domain only 2
chr17_-_69141878 0.95 ENST00000590645.1
ENST00000284425.7
ATP binding cassette subfamily A member 6
chr2_+_172821575 0.94 ENST00000397087.7
Rap guanine nucleotide exchange factor 4
chr2_-_237590660 0.93 ENST00000409576.1
RAB17, member RAS oncogene family
chr9_-_137302264 0.90 ENST00000356628.4
NOTCH regulated ankyrin repeat protein
chr11_-_118264282 0.90 ENST00000278937.7
myelin protein zero like 2
chr12_+_53050014 0.89 ENST00000314250.11
tensin 2
chr2_+_15940537 0.88 ENST00000281043.4
ENST00000638417.1
MYCN proto-oncogene, bHLH transcription factor
chr2_+_69013170 0.87 ENST00000303714.9
ANTXR cell adhesion molecule 1
chr19_-_18941184 0.86 ENST00000594794.5
ENST00000392351.8
ENST00000596482.5
homer scaffold protein 3
chr22_-_24245059 0.85 ENST00000398292.3
ENST00000263112.11
ENST00000327365.10
ENST00000424217.1
gamma-glutamyltransferase 5
chr22_-_37484505 0.84 ENST00000442496.1
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr12_+_53046969 0.82 ENST00000379902.7
tensin 2
chr1_+_32362537 0.82 ENST00000373534.4
testis specific serine kinase 3
chr19_-_38426162 0.81 ENST00000587738.2
ENST00000586305.5
RAS guanyl releasing protein 4
chr7_-_151057880 0.80 ENST00000485972.6
cyclin dependent kinase 5
chr19_-_38426195 0.79 ENST00000615439.5
ENST00000614135.4
ENST00000622174.4
ENST00000587753.5
ENST00000454404.6
ENST00000617966.4
ENST00000618320.4
ENST00000293062.13
ENST00000433821.6
ENST00000426920.6
RAS guanyl releasing protein 4
chr14_+_61187544 0.79 ENST00000555185.5
ENST00000557294.5
ENST00000556778.5
protein kinase C eta
chr2_-_218002988 0.79 ENST00000682258.1
ENST00000446903.5
tensin 1
chr8_-_17676484 0.78 ENST00000634613.1
ENST00000519066.5
microtubule associated scaffold protein 1
chr18_+_8717371 0.78 ENST00000359865.7
microtubule crosslinking factor 1
chr7_+_94394886 0.77 ENST00000297268.11
ENST00000620463.1
collagen type I alpha 2 chain
chr20_+_36092698 0.76 ENST00000430276.5
ENST00000373950.6
ENST00000373946.7
ENST00000441639.5
ENST00000628415.2
ENST00000452261.5
erythrocyte membrane protein band 4.1 like 1
chr8_-_17722217 0.76 ENST00000381861.7
microtubule associated scaffold protein 1
chr17_-_41572052 0.76 ENST00000588431.1
ENST00000246662.9
keratin 9
chr21_-_44592505 0.75 ENST00000400368.1
keratin associated protein 10-6
chrX_+_153494970 0.74 ENST00000331595.9
ENST00000431891.1
biglycan
chr8_-_22693469 0.73 ENST00000317216.3
early growth response 3
chr6_+_146598979 0.73 ENST00000681847.1
androglobin
chr12_-_14951106 0.73 ENST00000541644.5
ENST00000545895.5
Rho GDP dissociation inhibitor beta
chr5_-_111757465 0.73 ENST00000446294.6
neuronal regeneration related protein
chr5_-_111757175 0.73 ENST00000509025.5
ENST00000257435.12
ENST00000515855.5
neuronal regeneration related protein
chr3_+_152300135 0.72 ENST00000465907.6
ENST00000492948.5
ENST00000485509.5
ENST00000464596.5
muscleblind like splicing regulator 1
chr21_+_44600597 0.72 ENST00000609664.2
keratin associated protein 10-7
chr1_+_148748774 0.71 ENST00000322209.5
nudix hydrolase 4B
chr6_+_30882914 0.71 ENST00000509639.5
ENST00000412274.6
ENST00000507901.5
ENST00000507046.5
ENST00000437124.6
ENST00000454612.6
ENST00000396342.6
discoidin domain receptor tyrosine kinase 1
chr19_-_49020523 0.71 ENST00000637680.1
novel protein
chr13_-_106535653 0.70 ENST00000646441.1
ephrin B2
chr5_-_111757704 0.69 ENST00000379671.7
neuronal regeneration related protein
chr14_-_104978360 0.69 ENST00000333244.6
AHNAK nucleoprotein 2
chr9_-_72953047 0.68 ENST00000297785.8
ENST00000376939.5
aldehyde dehydrogenase 1 family member A1
chr3_+_12796662 0.67 ENST00000456430.6
ENST00000626378.1
cullin associated and neddylation dissociated 2 (putative)
chr2_-_27335403 0.67 ENST00000454704.5
general transcription factor IIIC subunit 2
chr19_+_35282520 0.66 ENST00000222304.5
hepcidin antimicrobial peptide
chr7_-_151057848 0.66 ENST00000297518.4
cyclin dependent kinase 5
chr19_+_17406099 0.65 ENST00000634942.2
ENST00000634568.1
ENST00000600514.5
BST2 interferon stimulated positive regulator
multivesicular body subunit 12A
chrX_+_54920796 0.65 ENST00000442098.5
ENST00000430420.5
ENST00000453081.5
ENST00000319167.12
ENST00000622017.4
ENST00000375022.8
ENST00000399736.5
ENST00000440072.5
ENST00000173898.12
ENST00000431115.5
ENST00000440759.5
ENST00000375041.6
trophinin
chr9_-_127854636 0.65 ENST00000344849.4
ENST00000373203.9
endoglin
chr9_+_137225166 0.65 ENST00000650725.2
cysteine rich tail 1
chr9_-_127847117 0.65 ENST00000480266.5
endoglin
chr20_+_63554142 0.64 ENST00000370097.2
fibronectin type III domain containing 11
chr6_+_137871208 0.64 ENST00000614035.4
ENST00000621150.3
ENST00000619035.4
ENST00000615468.4
ENST00000620204.3
TNF alpha induced protein 3
chr14_-_106875069 0.64 ENST00000390639.2
immunoglobulin heavy variable 7-81 (non-functional)
chr9_-_14180779 0.64 ENST00000380924.1
ENST00000543693.5
nuclear factor I B
chr2_+_33134579 0.63 ENST00000418533.6
latent transforming growth factor beta binding protein 1
chr2_+_33134620 0.63 ENST00000402934.5
ENST00000404525.5
ENST00000407925.5
latent transforming growth factor beta binding protein 1
chr7_-_120857124 0.63 ENST00000441017.5
ENST00000424710.5
ENST00000433758.5
tetraspanin 12
chr17_-_63699730 0.62 ENST00000578061.5
LIM domain containing 2
chr3_+_127598400 0.62 ENST00000265056.12
minichromosome maintenance complex component 2
chr5_-_111757382 0.62 ENST00000453526.6
ENST00000509427.5
neuronal regeneration related protein
chr19_+_45469841 0.62 ENST00000592811.5
ENST00000586615.5
FosB proto-oncogene, AP-1 transcription factor subunit
chr3_+_37975773 0.62 ENST00000436654.1
CTD small phosphatase like
chr3_+_141384790 0.61 ENST00000507722.5
zinc finger and BTB domain containing 38
chr16_-_10559135 0.61 ENST00000536829.1
epithelial membrane protein 2
chr5_-_111757549 0.61 ENST00000419114.6
neuronal regeneration related protein
chr12_-_14950606 0.61 ENST00000536592.5
Rho GDP dissociation inhibitor beta
chr11_+_34622053 0.61 ENST00000530286.5
ENST00000533754.5
ETS homologous factor
chr9_+_137077467 0.61 ENST00000409858.8
UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
chr11_+_847197 0.60 ENST00000532375.5
ENST00000346501.8
tetraspanin 4
chr4_-_89838289 0.60 ENST00000336904.7
synuclein alpha
chr5_+_36151989 0.59 ENST00000274254.9
S-phase kinase associated protein 2
chr12_-_7695752 0.59 ENST00000329913.4
growth differentiation factor 3
chr1_+_153774210 0.58 ENST00000271857.6
solute carrier family 27 member 3
chr4_+_73740541 0.58 ENST00000401931.1
ENST00000307407.8
C-X-C motif chemokine ligand 8
chr4_-_101347327 0.57 ENST00000394853.8
protein phosphatase 3 catalytic subunit alpha
chr9_+_2157647 0.57 ENST00000452193.5
ENST00000324954.10
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr19_+_34994778 0.56 ENST00000599564.5
GRAM domain containing 1A
chr8_+_30095649 0.56 ENST00000518192.5
leptin receptor overlapping transcript like 1
chr1_+_212608628 0.56 ENST00000613954.4
ENST00000341491.9
ENST00000366985.5
activating transcription factor 3
chr4_-_101346842 0.56 ENST00000507176.5
protein phosphatase 3 catalytic subunit alpha
chr18_+_79863668 0.56 ENST00000316249.3
potassium voltage-gated channel modifier subfamily G member 2
chr8_-_102655707 0.55 ENST00000285407.11
Kruppel like factor 10
chr14_+_103121457 0.54 ENST00000333007.8
TNF alpha induced protein 2
chr1_+_203626813 0.54 ENST00000357681.10
ATPase plasma membrane Ca2+ transporting 4
chr20_-_59007210 0.53 ENST00000681175.1
ENST00000681416.1
ENST00000680753.1
ENST00000680995.1
ENST00000680206.1
ENST00000680879.1
ENST00000217131.6
ENST00000680738.1
ENST00000679948.1
ENST00000680880.1
ENST00000681877.1
cathepsin Z
chr18_+_75210789 0.53 ENST00000580243.3
teashirt zinc finger homeobox 1
chr7_+_114922346 0.53 ENST00000393486.5
MyoD family inhibitor domain containing
chr12_-_12338674 0.52 ENST00000545735.1
MANSC domain containing 1
chr5_-_111757643 0.52 ENST00000508870.5
neuronal regeneration related protein
chr1_+_155127866 0.52 ENST00000368406.2
ENST00000368407.8
ephrin A1
chr2_+_238138661 0.51 ENST00000409223.2
kelch like family member 30
chr11_+_65111845 0.51 ENST00000526809.5
ENST00000524986.5
ENST00000534371.5
ENST00000279263.14
ENST00000525385.5
ENST00000345348.9
ENST00000531321.5
ENST00000529414.5
ENST00000526085.5
ENST00000530750.5
transmembrane 7 superfamily member 2
chrX_-_120560884 0.51 ENST00000404115.8
cullin 4B
chr19_+_735026 0.51 ENST00000592155.5
ENST00000590161.2
paralemmin
chr12_-_52796110 0.51 ENST00000417996.2
keratin 3
chrX_+_136197039 0.51 ENST00000370683.6
four and a half LIM domains 1
chr1_+_203626775 0.51 ENST00000367218.7
ATPase plasma membrane Ca2+ transporting 4
chr8_+_30095400 0.50 ENST00000321250.13
ENST00000518001.1
ENST00000520682.5
ENST00000442880.6
ENST00000523116.5
leptin receptor overlapping transcript like 1
chr18_+_75210755 0.49 ENST00000322038.5
teashirt zinc finger homeobox 1
chr14_-_24337382 0.49 ENST00000555591.1
ENST00000554569.1
novel transcript
receptor interacting serine/threonine kinase 3
chr8_+_22567038 0.48 ENST00000523348.1
sorbin and SH3 domain containing 3
chr2_-_74440484 0.48 ENST00000305557.9
ENST00000233330.6
rhotekin
chr14_-_22957100 0.48 ENST00000555367.5
HAUS augmin like complex subunit 4
chr9_+_79573162 0.48 ENST00000425506.5
TLE family member 4, transcriptional corepressor
chr9_-_120714457 0.48 ENST00000373930.4
multiple EGF like domains 9
chr10_-_70376779 0.47 ENST00000395011.5
leucine rich repeat containing 20
chr14_-_22957061 0.47 ENST00000557591.5
ENST00000541587.6
ENST00000490506.5
ENST00000554406.1
HAUS augmin like complex subunit 4
chr1_-_46132650 0.47 ENST00000372006.5
ENST00000425892.2
ENST00000420542.5
phosphoinositide-3-kinase regulatory subunit 3
chr1_-_169630115 0.46 ENST00000263686.11
ENST00000367788.6
selectin P
chr14_-_22819721 0.46 ENST00000554517.5
ENST00000285850.11
ENST00000397529.6
ENST00000555702.5
solute carrier family 7 member 7
chr11_+_59755398 0.46 ENST00000633708.1
syntaxin 3
chr6_-_2971048 0.46 ENST00000612421.3
serpin family B member 6
chr9_+_79572572 0.46 ENST00000435650.5
ENST00000414465.5
ENST00000376537.8
TLE family member 4, transcriptional corepressor
chr14_-_22957128 0.46 ENST00000342454.12
ENST00000555986.5
ENST00000554516.5
ENST00000347758.6
ENST00000206474.11
ENST00000555040.5
HAUS augmin like complex subunit 4
chr22_+_22871478 0.46 ENST00000390318.2
immunoglobulin lambda variable 4-3
chr21_+_44573724 0.45 ENST00000622352.3
ENST00000400374.4
ENST00000616689.2
keratin associated protein 10-4
chr16_+_58025745 0.45 ENST00000219271.4
matrix metallopeptidase 15
chr22_+_31092447 0.45 ENST00000455608.5
smoothelin
chr9_-_21202205 0.45 ENST00000239347.3
interferon alpha 7
chr9_+_79572715 0.44 ENST00000265284.10
TLE family member 4, transcriptional corepressor
chr1_-_46132616 0.44 ENST00000423209.5
ENST00000262741.10
phosphoinositide-3-kinase regulatory subunit 3
chr13_+_102656933 0.44 ENST00000650757.1
tripeptidyl peptidase 2
chr1_+_1280436 0.44 ENST00000379116.10
sodium channel epithelial 1 subunit delta
chr19_+_49114324 0.43 ENST00000391864.7
lin-7 homolog B, crumbs cell polarity complex component
chr19_+_17405734 0.43 ENST00000635572.1
ENST00000634675.1
ENST00000634813.1
ENST00000647283.1
ENST00000635435.2
ENST00000634731.2
ENST00000635339.1
ENST00000528604.5
BST2 interferon stimulated positive regulator
multivesicular body subunit 12A
chr21_-_38660656 0.43 ENST00000398919.6
ETS transcription factor ERG
chr4_+_30720348 0.43 ENST00000361762.3
protocadherin 7
chr14_-_54488940 0.43 ENST00000628554.2
ENST00000358056.8
glia maturation factor beta
chr11_-_62707581 0.43 ENST00000684475.1
ENST00000683296.1
ENST00000684067.1
ENST00000682223.1
BSCL2 lipid droplet biogenesis associated, seipin
chr2_-_208255055 0.42 ENST00000345146.7
isocitrate dehydrogenase (NADP(+)) 1
chr17_+_63550521 0.42 ENST00000615512.1
DDB1 and CUL4 associated factor 7
chrX_-_19799751 0.42 ENST00000379698.8
SH3 domain containing kinase binding protein 1
chrX_+_150361559 0.42 ENST00000262858.8
mastermind like domain containing 1
chr8_-_30083053 0.42 ENST00000256255.11
ENST00000523761.1
store-operated calcium entry associated regulatory factor
chr22_+_31082860 0.41 ENST00000619644.4
smoothelin
chr8_-_30083110 0.41 ENST00000545648.2
store-operated calcium entry associated regulatory factor
chr11_-_134223929 0.41 ENST00000534548.7
non-SMC condensin II complex subunit D3
chr6_-_132798587 0.41 ENST00000275227.9
solute carrier family 18 member B1
chr22_-_18518161 0.41 ENST00000619998.1
gamma-glutamyltransferase light chain family member 3
chr1_+_228458095 0.41 ENST00000620438.1
H2B.U histone 1
chr1_+_228149922 0.41 ENST00000366714.3
gap junction protein gamma 2
chr19_-_4559663 0.41 ENST00000586582.6
semaphorin 6B
chrX_+_136197020 0.41 ENST00000370676.7
four and a half LIM domains 1
chr11_+_64251483 0.40 ENST00000279230.12
ENST00000540288.5
ENST00000325234.5
phospholipase C beta 3
chr15_-_82647960 0.40 ENST00000615198.4
cytoplasmic polyadenylation element binding protein 1
chr19_-_6670117 0.40 ENST00000245912.7
TNF superfamily member 14
chr6_+_143536811 0.39 ENST00000367584.8
phosphatase and actin regulator 2
chr16_-_2329687 0.39 ENST00000567910.1
ATP binding cassette subfamily A member 3
chr2_+_42494547 0.39 ENST00000405592.5
metastasis associated 1 family member 3
chr19_-_49361475 0.39 ENST00000598810.5
TEA domain transcription factor 2
chr19_+_17405685 0.39 ENST00000646744.1
ENST00000635536.2
ENST00000635060.2
ENST00000634291.2
ENST00000645298.1
ENST00000528911.5
BST2 interferon stimulated positive regulator
multivesicular body subunit 12A
chr20_-_57690624 0.39 ENST00000414037.5
prostate transmembrane protein, androgen induced 1
chr11_-_76669985 0.39 ENST00000407242.6
ENST00000421973.1
leucine rich repeat containing 32
chr17_-_35868885 0.39 ENST00000604834.6
HEAT repeat containing 9
chr3_+_184319677 0.39 ENST00000441154.5
eukaryotic translation initiation factor 4 gamma 1
chr19_-_51458448 0.39 ENST00000430817.5
ENST00000321424.7
ENST00000340550.5
sialic acid binding Ig like lectin 8
chr7_+_116672187 0.39 ENST00000318493.11
ENST00000397752.8
MET proto-oncogene, receptor tyrosine kinase
chr2_+_230878139 0.38 ENST00000620962.1
integral membrane protein 2C
chr19_-_49362376 0.38 ENST00000601519.5
ENST00000593945.6
ENST00000539846.5
ENST00000596757.1
ENST00000311227.6
TEA domain transcription factor 2
chr22_-_21225554 0.38 ENST00000405188.8
gamma-glutamyltransferase 2
chr22_+_50089879 0.38 ENST00000545383.5
ENST00000262794.10
Mov10 like RISC complex RNA helicase 1
chr20_+_33031648 0.38 ENST00000349552.1
BPI fold containing family B member 6
chr12_-_31591129 0.38 ENST00000389082.10
DENN domain containing 5B
chr5_+_157269317 0.38 ENST00000618329.4
cytoplasmic FMR1 interacting protein 2
chr19_-_41353904 0.38 ENST00000221930.6
transforming growth factor beta 1
chr11_-_62707413 0.38 ENST00000360796.10
ENST00000449636.6
BSCL2 lipid droplet biogenesis associated, seipin
chr3_+_159988828 0.38 ENST00000305579.7
ENST00000480787.5
ENST00000466512.1
interleukin 12A
chrX_-_149595314 0.37 ENST00000598963.3
heat shock transcription factor family, X-linked 2
chr19_+_17470474 0.37 ENST00000598424.5
ENST00000252595.12
solute carrier family 27 member 1
chr1_+_26543106 0.37 ENST00000530003.5
ribosomal protein S6 kinase A1
chr12_-_1918639 0.37 ENST00000382722.10
calcium voltage-gated channel auxiliary subunit alpha2delta 4
chr8_-_30082948 0.37 ENST00000521265.5
store-operated calcium entry associated regulatory factor
chr12_+_6924449 0.37 ENST00000356654.8
atrophin 1
chr14_+_91114667 0.37 ENST00000523894.5
ENST00000522322.5
ENST00000523771.5
D-glutamate cyclase

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.5 1.1 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.5 1.5 GO:0038162 erythropoietin-mediated signaling pathway(GO:0038162) mast cell proliferation(GO:0070662)
0.4 1.3 GO:0001300 chronological cell aging(GO:0001300)
0.4 1.2 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.4 1.5 GO:2000170 positive regulation of peptidyl-cysteine S-nitrosylation(GO:2000170)
0.3 1.0 GO:1903248 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.3 1.5 GO:0019075 virus maturation(GO:0019075)
0.3 3.2 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.3 1.1 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
0.2 1.2 GO:1901202 negative regulation of extracellular matrix assembly(GO:1901202)
0.2 0.7 GO:0061536 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.2 1.4 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.2 1.3 GO:0071461 cellular response to redox state(GO:0071461)
0.2 0.7 GO:1990641 response to iron ion starvation(GO:1990641)
0.2 0.6 GO:0034148 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429)
0.2 0.6 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.2 1.5 GO:0003172 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.2 0.6 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.2 0.4 GO:2000793 cell proliferation involved in heart valve development(GO:2000793)
0.2 1.0 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.2 0.5 GO:0014028 notochord formation(GO:0014028)
0.2 1.0 GO:0060023 soft palate development(GO:0060023)
0.2 0.5 GO:0035698 CD8-positive, alpha-beta cytotoxic T cell extravasation(GO:0035698) regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation(GO:2000452)
0.2 1.6 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.2 1.4 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.2 1.3 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.2 0.9 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 0.9 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.1 0.7 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.1 0.6 GO:0032765 positive regulation of mast cell cytokine production(GO:0032765)
0.1 0.4 GO:0006097 glyoxylate cycle(GO:0006097)
0.1 0.4 GO:0048058 compound eye corneal lens development(GO:0048058)
0.1 1.5 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.1 1.0 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.1 0.4 GO:0001579 medium-chain fatty acid transport(GO:0001579)
0.1 0.1 GO:0002625 regulation of T cell antigen processing and presentation(GO:0002625)
0.1 0.4 GO:0003099 positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.1 2.2 GO:1901750 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.1 0.6 GO:0032185 septin cytoskeleton organization(GO:0032185)
0.1 1.1 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.1 0.4 GO:0042412 taurine biosynthetic process(GO:0042412)
0.1 0.5 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.1 0.6 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.1 0.4 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.1 0.2 GO:0035262 gonad morphogenesis(GO:0035262)
0.1 0.1 GO:0050883 musculoskeletal movement, spinal reflex action(GO:0050883)
0.1 0.3 GO:0051365 leading edge cell differentiation(GO:0035026) cellular response to potassium ion starvation(GO:0051365)
0.1 0.6 GO:1903282 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.1 0.7 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.1 0.2 GO:0033591 response to L-ascorbic acid(GO:0033591)
0.1 0.4 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.1 0.7 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586)
0.1 0.3 GO:0072428 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.1 0.5 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.1 0.1 GO:2001201 regulation of transforming growth factor-beta secretion(GO:2001201)
0.1 3.2 GO:0014850 response to muscle activity(GO:0014850)
0.1 2.4 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.1 1.2 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.1 0.7 GO:0042791 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.1 0.9 GO:0034350 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.1 1.1 GO:0044857 plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857)
0.1 0.2 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 0.2 GO:0006212 uracil catabolic process(GO:0006212)
0.1 0.2 GO:0097274 ammonia homeostasis(GO:0097272) urea homeostasis(GO:0097274)
0.1 0.6 GO:2000535 regulation of entry of bacterium into host cell(GO:2000535)
0.1 0.2 GO:0072683 T cell extravasation(GO:0072683)
0.1 0.3 GO:0051410 detoxification of nitrogen compound(GO:0051410) cellular detoxification of nitrogen compound(GO:0070458)
0.1 0.8 GO:2000576 positive regulation of microtubule motor activity(GO:2000576)
0.1 0.7 GO:0010265 SCF complex assembly(GO:0010265)
0.1 0.5 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.1 0.4 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.1 0.5 GO:0060160 negative regulation of dopamine receptor signaling pathway(GO:0060160)
0.1 0.4 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.1 0.3 GO:0002644 negative regulation of tolerance induction(GO:0002644)
0.1 0.4 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.1 0.3 GO:0019418 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.1 0.2 GO:0033037 polysaccharide localization(GO:0033037)
0.1 0.4 GO:0070495 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.1 1.2 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.1 0.3 GO:0044856 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.1 0.3 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.1 0.5 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.1 0.3 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.1 0.3 GO:0042335 cuticle development(GO:0042335)
0.1 0.4 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.1 0.7 GO:0072178 nephric duct morphogenesis(GO:0072178)
0.1 0.9 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.1 0.2 GO:0044778 meiotic DNA integrity checkpoint(GO:0044778)
0.1 0.2 GO:1903756 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.1 0.2 GO:0060957 endocardial cell fate commitment(GO:0060957) endocardial cushion cell fate commitment(GO:0061445)
0.1 0.7 GO:0006824 cobalt ion transport(GO:0006824)
0.1 0.2 GO:0052314 phytoalexin metabolic process(GO:0052314)
0.1 0.6 GO:0051135 positive regulation of NK T cell activation(GO:0051135)
0.1 0.2 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.1 0.8 GO:0043589 skin morphogenesis(GO:0043589)
0.1 0.1 GO:0070428 regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428)
0.1 0.4 GO:0002774 Fc receptor mediated inhibitory signaling pathway(GO:0002774)
0.1 0.8 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 1.5 GO:0072189 ureter development(GO:0072189)
0.1 0.2 GO:0015993 molecular hydrogen transport(GO:0015993)
0.1 0.7 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 0.5 GO:0070294 renal sodium ion absorption(GO:0070294)
0.1 0.2 GO:1903570 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.0 0.8 GO:0030903 notochord development(GO:0030903)
0.0 1.0 GO:0042789 mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.0 0.3 GO:0034197 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.0 0.3 GO:0060574 intestinal epithelial cell maturation(GO:0060574)
0.0 1.6 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.0 0.2 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.0 0.1 GO:0006679 glucosylceramide biosynthetic process(GO:0006679)
0.0 0.5 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.0 0.2 GO:0021590 cerebellum maturation(GO:0021590) cerebellar cortex maturation(GO:0021699)
0.0 0.5 GO:0061368 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0 0.1 GO:1901874 negative regulation of post-translational protein modification(GO:1901874)
0.0 0.3 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.0 0.2 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.0 0.8 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 1.9 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.2 GO:0000393 spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
0.0 0.0 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.0 0.3 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.0 0.7 GO:0051601 exocyst localization(GO:0051601)
0.0 0.3 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
0.0 0.5 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 0.4 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 0.3 GO:0075044 autophagy of host cells involved in interaction with symbiont(GO:0075044) autophagy involved in symbiotic interaction(GO:0075071)
0.0 0.2 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.0 0.7 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.4 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 0.1 GO:0060369 positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
0.0 0.4 GO:0050703 interleukin-1 alpha secretion(GO:0050703)
0.0 0.1 GO:0098758 response to interleukin-8(GO:0098758) cellular response to interleukin-8(GO:0098759)
0.0 0.3 GO:0019236 response to pheromone(GO:0019236)
0.0 0.1 GO:0001808 negative regulation of type IV hypersensitivity(GO:0001808)
0.0 0.8 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.0 0.2 GO:0046092 deoxycytidine metabolic process(GO:0046092)
0.0 0.6 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.2 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.0 1.0 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.0 0.3 GO:0035166 post-embryonic hemopoiesis(GO:0035166)
0.0 2.0 GO:0071470 cellular response to osmotic stress(GO:0071470)
0.0 0.1 GO:0006669 sphinganine-1-phosphate biosynthetic process(GO:0006669)
0.0 0.2 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.1 GO:0097698 telomere maintenance via base-excision repair(GO:0097698)
0.0 1.2 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 1.1 GO:0002323 natural killer cell activation involved in immune response(GO:0002323)
0.0 0.4 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
0.0 0.5 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.0 0.9 GO:0045109 intermediate filament organization(GO:0045109)
0.0 0.2 GO:0072718 response to cisplatin(GO:0072718)
0.0 0.1 GO:0015862 uridine transport(GO:0015862)
0.0 0.2 GO:0060481 lobar bronchus epithelium development(GO:0060481)
0.0 0.3 GO:0045059 positive thymic T cell selection(GO:0045059)
0.0 0.3 GO:0010593 negative regulation of lamellipodium assembly(GO:0010593)
0.0 0.1 GO:0007056 spindle assembly involved in female meiosis(GO:0007056)
0.0 0.5 GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.0 0.6 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.0 0.1 GO:0071922 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0 0.1 GO:2000405 negative regulation of establishment of T cell polarity(GO:1903904) negative regulation of T cell migration(GO:2000405) negative regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001107)
0.0 0.1 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.0 0.4 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.2 GO:0031133 regulation of axon diameter(GO:0031133)
0.0 0.1 GO:1901876 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.0 0.2 GO:0021834 chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration(GO:0021834)
0.0 0.1 GO:2000983 regulation of ATP citrate synthase activity(GO:2000983) negative regulation of ATP citrate synthase activity(GO:2000984)
0.0 0.5 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.2 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.0 0.1 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.0 0.7 GO:0045104 intermediate filament cytoskeleton organization(GO:0045104)
0.0 0.0 GO:0043316 cytotoxic T cell degranulation(GO:0043316)
0.0 0.5 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.3 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.2 GO:0002084 protein depalmitoylation(GO:0002084)
0.0 0.1 GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
0.0 0.3 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 0.1 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.0 1.6 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 0.1 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
0.0 0.1 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
0.0 0.7 GO:0050995 negative regulation of lipid catabolic process(GO:0050995)
0.0 0.1 GO:0048213 Golgi vesicle prefusion complex stabilization(GO:0048213)
0.0 0.3 GO:1904903 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.0 0.4 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 0.2 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 1.4 GO:0010761 fibroblast migration(GO:0010761)
0.0 0.4 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.1 GO:2000196 positive regulation of female gonad development(GO:2000196)
0.0 0.3 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.0 0.4 GO:0051770 positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)
0.0 0.1 GO:0060620 regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.0 0.1 GO:0034184 positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184) protein localization to site of double-strand break(GO:1990166)
0.0 0.1 GO:0070889 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) platelet alpha granule organization(GO:0070889) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.0 0.1 GO:0015705 iodide transport(GO:0015705)
0.0 0.2 GO:0071888 macrophage apoptotic process(GO:0071888)
0.0 0.3 GO:0019317 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 0.1 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.0 0.1 GO:0061591 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.0 0.1 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.0 0.2 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.1 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.1 GO:0016321 female meiosis chromosome segregation(GO:0016321)
0.0 0.1 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0 0.1 GO:0031550 positive regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031550)
0.0 0.3 GO:0045116 protein neddylation(GO:0045116)
0.0 0.2 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.1 GO:0060133 somatotropin secreting cell development(GO:0060133)
0.0 0.1 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
0.0 1.0 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.1 GO:0071415 cellular response to purine-containing compound(GO:0071415)
0.0 0.1 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 0.1 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.2 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0 0.1 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.0 0.1 GO:0090037 positive regulation of protein kinase C signaling(GO:0090037)
0.0 0.0 GO:0072209 positive regulation of glomerular filtration(GO:0003104) metanephric mesangial cell differentiation(GO:0072209) metanephric glomerular mesangial cell differentiation(GO:0072254) negative regulation of vascular smooth muscle cell differentiation(GO:1905064)
0.0 0.1 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.0 0.0 GO:0010958 regulation of amino acid import(GO:0010958)
0.0 0.0 GO:0060823 canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060823)
0.0 0.0 GO:0045918 negative regulation of cytolysis(GO:0045918)
0.0 0.1 GO:0034227 tRNA thio-modification(GO:0034227)
0.0 0.4 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.0 0.0 GO:0019858 cytosine metabolic process(GO:0019858)
0.0 0.1 GO:0097327 response to antineoplastic agent(GO:0097327)
0.0 0.2 GO:0019370 leukotriene biosynthetic process(GO:0019370)
0.0 0.7 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.1 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0 0.1 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.0 0.5 GO:0010842 retina layer formation(GO:0010842)
0.0 0.1 GO:0061087 regulation of histone H3-K27 methylation(GO:0061085) positive regulation of histone H3-K27 methylation(GO:0061087)
0.0 0.1 GO:0022614 membrane to membrane docking(GO:0022614)
0.0 0.3 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 0.1 GO:0021759 globus pallidus development(GO:0021759)
0.0 0.1 GO:0032072 plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072) T-helper 1 cell activation(GO:0035711)
0.0 0.7 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.0 0.4 GO:0016180 snRNA processing(GO:0016180)
0.0 0.3 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.0 0.1 GO:0046541 saliva secretion(GO:0046541)
0.0 0.2 GO:0060263 regulation of respiratory burst(GO:0060263)
0.0 0.1 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.0 0.1 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.0 0.3 GO:0034656 nucleobase-containing small molecule catabolic process(GO:0034656)
0.0 0.4 GO:1900746 regulation of vascular endothelial growth factor signaling pathway(GO:1900746)
0.0 0.1 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.0 2.9 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.5 GO:0014072 response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.0 1.1 GO:0001895 retina homeostasis(GO:0001895)
0.0 0.2 GO:0045618 positive regulation of keratinocyte differentiation(GO:0045618)
0.0 0.2 GO:0042534 tumor necrosis factor biosynthetic process(GO:0042533) regulation of tumor necrosis factor biosynthetic process(GO:0042534)
0.0 0.2 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 0.4 GO:0006266 DNA ligation(GO:0006266)
0.0 1.6 GO:0051225 spindle assembly(GO:0051225)
0.0 0.3 GO:0035313 wound healing, spreading of epidermal cells(GO:0035313)
0.0 2.4 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 1.1 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.0 0.2 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.2 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 0.2 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 0.1 GO:1902237 positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902237)
0.0 0.2 GO:0050812 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0 0.4 GO:0001783 B cell apoptotic process(GO:0001783)
0.0 0.0 GO:1904179 regulation of adipose tissue development(GO:1904177) positive regulation of adipose tissue development(GO:1904179)
0.0 0.1 GO:0002225 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antibacterial peptide production(GO:0002803)
0.0 0.0 GO:2000394 positive regulation of lamellipodium morphogenesis(GO:2000394)
0.0 0.2 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.0 0.1 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 0.3 GO:0060065 uterus development(GO:0060065)
0.0 0.2 GO:0009650 UV protection(GO:0009650)
0.0 0.0 GO:0030047 actin modification(GO:0030047)
0.0 0.1 GO:0010248 establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.0 0.1 GO:0055129 L-proline biosynthetic process(GO:0055129)
0.0 0.2 GO:0097201 negative regulation of inclusion body assembly(GO:0090084) negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
0.0 0.1 GO:0070574 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0 0.0 GO:2000630 positive regulation of miRNA metabolic process(GO:2000630)
0.0 0.1 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0072563 endothelial microparticle(GO:0072563)
0.3 1.6 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.3 1.5 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.2 0.8 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.2 0.6 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.1 0.4 GO:0000799 nuclear condensin complex(GO:0000799)
0.1 1.5 GO:0070652 HAUS complex(GO:0070652)
0.1 0.4 GO:0097232 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.1 3.3 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 0.4 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.1 1.1 GO:0005955 calcineurin complex(GO:0005955)
0.1 0.3 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.1 1.5 GO:0000813 ESCRT I complex(GO:0000813)
0.1 0.7 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.1 0.3 GO:0071821 FANCM-MHF complex(GO:0071821)
0.1 2.9 GO:0031527 filopodium membrane(GO:0031527)
0.1 0.8 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 0.2 GO:0001534 radial spoke(GO:0001534)
0.1 0.8 GO:0097427 microtubule bundle(GO:0097427)
0.1 1.0 GO:0042555 MCM complex(GO:0042555)
0.1 1.4 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.1 0.3 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.1 0.1 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.1 0.3 GO:0070557 PCNA-p21 complex(GO:0070557)
0.1 0.2 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.1 0.8 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 2.1 GO:0042629 mast cell granule(GO:0042629)
0.1 0.6 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 0.8 GO:0031906 late endosome lumen(GO:0031906)
0.1 0.3 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.1 2.1 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 0.3 GO:0031417 NatC complex(GO:0031417)
0.1 0.7 GO:0045179 apical cortex(GO:0045179)
0.0 0.8 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.3 GO:0035976 AP1 complex(GO:0035976)
0.0 0.4 GO:0071546 pi-body(GO:0071546)
0.0 0.2 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.0 0.9 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.9 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.2 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 0.2 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
0.0 0.2 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.6 GO:0032039 integrator complex(GO:0032039)
0.0 0.1 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.0 0.2 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.2 GO:0036021 endolysosome lumen(GO:0036021)
0.0 0.3 GO:0097255 R2TP complex(GO:0097255)
0.0 0.8 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.8 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.1 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0 0.3 GO:0070552 BRISC complex(GO:0070552)
0.0 0.1 GO:1990357 terminal web(GO:1990357)
0.0 0.2 GO:0044305 calyx of Held(GO:0044305)
0.0 0.5 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.2 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.0 0.4 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.2 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.7 GO:0000145 exocyst(GO:0000145)
0.0 0.2 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 1.1 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.1 GO:0060171 stereocilium membrane(GO:0060171)
0.0 0.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.3 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.3 GO:0030478 actin cap(GO:0030478)
0.0 0.2 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.0 0.5 GO:0097342 ripoptosome(GO:0097342)
0.0 1.9 GO:0045178 basal part of cell(GO:0045178)
0.0 2.2 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.0 0.1 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.0 0.1 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.1 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.8 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.4 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.4 GO:0036038 MKS complex(GO:0036038)
0.0 0.7 GO:0043034 costamere(GO:0043034)
0.0 0.4 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 1.5 GO:0045095 keratin filament(GO:0045095)
0.0 0.1 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.0 0.6 GO:0099738 cell cortex region(GO:0099738)
0.0 0.1 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.1 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.7 GO:0097228 sperm principal piece(GO:0097228)
0.0 1.1 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.3 GO:0000815 ESCRT III complex(GO:0000815)
0.0 3.5 GO:0043197 dendritic spine(GO:0043197)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.1 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.3 GO:0032982 myosin filament(GO:0032982)
0.0 0.1 GO:0031523 Myb complex(GO:0031523)
0.0 0.8 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.9 GO:0016459 myosin complex(GO:0016459)
0.0 1.0 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.3 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.2 GO:0031045 dense core granule(GO:0031045)
0.0 0.3 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.4 GO:0034706 sodium channel complex(GO:0034706)
0.0 0.2 GO:0042627 chylomicron(GO:0042627)
0.0 0.1 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.0 0.0 GO:0044307 dendritic branch(GO:0044307)
0.0 0.1 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.4 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 1.9 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.4 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.0 GO:0097679 symbiont-containing vacuole(GO:0020003) other organism cytoplasm(GO:0097679)
0.0 1.3 GO:0036064 ciliary basal body(GO:0036064)
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)
0.0 1.5 GO:0043202 lysosomal lumen(GO:0043202)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
0.4 1.9 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.3 1.0 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.3 1.4 GO:0050436 microfibril binding(GO:0050436)
0.2 0.8 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.2 1.0 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.2 0.7 GO:0001069 regulatory region RNA binding(GO:0001069)
0.2 0.5 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.2 1.4 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.2 0.7 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.2 1.3 GO:0005534 galactose binding(GO:0005534)
0.2 0.9 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.2 0.6 GO:0005163 nerve growth factor receptor binding(GO:0005163)
0.2 0.9 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.1 0.4 GO:0005055 laminin receptor activity(GO:0005055)
0.1 0.4 GO:0051990 isocitrate dehydrogenase (NADP+) activity(GO:0004450) (R)-2-hydroxyglutarate dehydrogenase activity(GO:0051990)
0.1 1.1 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 2.2 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.1 2.0 GO:1901567 icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.1 0.7 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.1 0.6 GO:0032810 sterol response element binding(GO:0032810)
0.1 2.1 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.1 1.7 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.1 0.3 GO:0004958 prostaglandin F receptor activity(GO:0004958)
0.1 0.6 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.1 0.3 GO:0017129 triglyceride binding(GO:0017129)
0.1 0.3 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.1 0.5 GO:0043208 glycosphingolipid binding(GO:0043208)
0.1 0.9 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 1.5 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.1 0.1 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.1 0.3 GO:0052810 1-phosphatidylinositol-5-kinase activity(GO:0052810)
0.1 0.3 GO:0016503 pheromone receptor activity(GO:0016503)
0.1 0.4 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.1 0.2 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.1 1.5 GO:0003680 AT DNA binding(GO:0003680)
0.1 0.3 GO:0008311 double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.1 0.7 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 1.2 GO:0005132 type I interferon receptor binding(GO:0005132)
0.1 1.7 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 1.4 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 0.3 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.1 0.2 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.1 1.5 GO:0043422 protein kinase B binding(GO:0043422)
0.1 0.4 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 0.6 GO:0070569 uridylyltransferase activity(GO:0070569)
0.1 0.4 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.1 0.1 GO:0042610 CD8 receptor binding(GO:0042610)
0.1 0.5 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.1 0.4 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.1 0.2 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.1 0.3 GO:0031708 endothelin B receptor binding(GO:0031708)
0.1 0.2 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.1 0.2 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.0 0.2 GO:0031750 D3 dopamine receptor binding(GO:0031750)
0.0 0.7 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.1 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.2 GO:0043273 CTPase activity(GO:0043273)
0.0 1.4 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.6 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.2 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.0 0.6 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.4 GO:0032396 inhibitory MHC class I receptor activity(GO:0032396)
0.0 0.4 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.3 GO:0010465 neurotrophin p75 receptor binding(GO:0005166) nerve growth factor receptor activity(GO:0010465)
0.0 0.3 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.0 0.8 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.1 GO:0036134 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.0 0.3 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0 0.2 GO:0019770 IgG receptor activity(GO:0019770)
0.0 1.2 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.3 GO:0051022 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0 0.6 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.4 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.0 0.3 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.1 GO:0019959 interleukin-8 binding(GO:0019959)
0.0 0.1 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0 0.7 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.2 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.3 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.6 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.2 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.5 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0 0.4 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.0 0.5 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.3 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 1.5 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.4 GO:0008430 selenium binding(GO:0008430)
0.0 0.2 GO:0004137 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.0 0.5 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.3 GO:0019826 oxygen sensor activity(GO:0019826)
0.0 0.7 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.6 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.2 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.2 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.0 0.1 GO:0034584 piRNA binding(GO:0034584)
0.0 0.3 GO:1903763 gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.0 0.2 GO:0030172 troponin C binding(GO:0030172)
0.0 0.5 GO:0017166 vinculin binding(GO:0017166)
0.0 0.5 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.1 GO:0000247 C-8 sterol isomerase activity(GO:0000247)
0.0 0.5 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.4 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.7 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.2 GO:0019237 centromeric DNA binding(GO:0019237)
0.0 0.1 GO:0004368 glycerol-3-phosphate dehydrogenase activity(GO:0004368) oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.0 0.2 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.2 GO:0004522 ribonuclease A activity(GO:0004522)
0.0 0.8 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.5 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.2 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0 0.4 GO:0019211 phosphatase activator activity(GO:0019211)
0.0 0.1 GO:0052739 phosphatidylserine 1-acylhydrolase activity(GO:0052739)
0.0 0.1 GO:0032440 2-alkenal reductase [NAD(P)] activity(GO:0032440)
0.0 0.1 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.0 0.6 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.3 GO:0045159 myosin II binding(GO:0045159)
0.0 0.3 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.1 GO:0008453 alanine-glyoxylate transaminase activity(GO:0008453)
0.0 0.4 GO:0048156 tau protein binding(GO:0048156)
0.0 0.2 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.4 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.5 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.1 GO:0047693 GTP diphosphatase activity(GO:0036219) 2-hydroxy-adenosine triphosphate pyrophosphatase activity(GO:0044713) 2-hydroxy-(deoxy)adenosine-triphosphate pyrophosphatase activity(GO:0044714) ATP diphosphatase activity(GO:0047693)
0.0 0.1 GO:0004447 iodide peroxidase activity(GO:0004447)
0.0 0.3 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 1.1 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.2 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.9 GO:0070888 E-box binding(GO:0070888)
0.0 0.3 GO:0031432 titin binding(GO:0031432)
0.0 0.7 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 1.6 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.8 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.4 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.3 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931) calcium-dependent protein kinase activity(GO:0010857)
0.0 0.3 GO:0043295 glutathione binding(GO:0043295)
0.0 0.1 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.0 0.1 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.1 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 0.4 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.2 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.1 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.0 0.1 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.2 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.1 GO:0019958 C-X-C chemokine binding(GO:0019958)
0.0 0.3 GO:0019841 retinol binding(GO:0019841)
0.0 0.1 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.0 0.1 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0 0.0 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.0 0.8 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 6.5 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.6 GO:0050699 WW domain binding(GO:0050699)
0.0 0.1 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.0 0.1 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0 0.5 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.2 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.0 0.2 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.0 GO:0004051 arachidonate 5-lipoxygenase activity(GO:0004051)
0.0 0.1 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.0 0.3 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 2.3 GO:0005178 integrin binding(GO:0005178)
0.0 0.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.1 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 0.1 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.5 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.4 GO:0042605 peptide antigen binding(GO:0042605)
0.0 1.1 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.3 GO:0015101 organic cation transmembrane transporter activity(GO:0015101)
0.0 0.1 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 3.3 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)
0.0 0.1 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.1 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0 0.1 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.3 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.6 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.2 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.2 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.1 GO:0004046 aminoacylase activity(GO:0004046)
0.0 1.0 GO:0019003 GDP binding(GO:0019003)
0.0 0.2 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.1 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.0 1.8 GO:0002020 protease binding(GO:0002020)
0.0 0.1 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 0.2 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.3 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.1 GO:0019784 NEDD8-specific protease activity(GO:0019784)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.1 1.4 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 5.1 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.1 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 3.0 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.6 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 2.1 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.6 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 1.0 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.9 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 2.8 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 1.7 PID RAS PATHWAY Regulation of Ras family activation
0.0 2.0 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 2.1 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 1.6 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.9 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.6 PID ENDOTHELIN PATHWAY Endothelins
0.0 1.3 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 1.0 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 1.0 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.3 PID S1P S1P3 PATHWAY S1P3 pathway
0.0 0.8 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.7 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.6 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 0.6 PID AURORA A PATHWAY Aurora A signaling
0.0 0.9 PID ATR PATHWAY ATR signaling pathway
0.0 1.2 PID AP1 PATHWAY AP-1 transcription factor network
0.0 1.3 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.6 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 1.8 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.4 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.8 PID BMP PATHWAY BMP receptor signaling
0.0 0.6 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.5 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.3 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.3 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.4 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.5 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.1 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.5 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.9 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.1 1.9 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.1 0.7 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.1 1.8 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 1.6 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 1.0 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.1 1.3 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 1.9 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.7 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 1.9 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.5 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.9 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.0 0.7 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 1.4 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.4 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.9 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.4 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 1.0 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.3 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.9 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.3 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.4 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.6 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.7 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.5 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.3 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.5 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0 0.4 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 1.3 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 1.1 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.3 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.7 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.3 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.1 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 1.1 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.7 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 1.3 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.2 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.1 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.8 REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING Genes involved in Integrin alphaIIb beta3 signaling
0.0 0.3 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0 1.0 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.3 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.3 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.6 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.8 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.3 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.4 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.3 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.6 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.3 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.1 REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
0.0 0.4 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.2 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 1.0 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.7 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 0.2 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 1.3 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.5 REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
0.0 0.5 REACTOME KINESINS Genes involved in Kinesins
0.0 0.5 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.6 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.3 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.2 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.1 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.7 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.0 0.4 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.2 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.5 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.2 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 0.4 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.3 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling