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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for SOX1

Z-value: 0.67

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Transcription factors associated with SOX1

Gene Symbol Gene ID Gene Info
SOX1
ENSG00000182968.5 SOX1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX1hg38_v1_chr13_+_112067143_1120671600.009.9e-01Click!

Activity profile of SOX1 motif

Sorted Z-values of SOX1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr2_-_162318129 2.66 ENST00000679938.1
IFIH1
interferon induced with helicase C domain 1
chr1_-_12616762 2.38 ENST00000464917.5
DHRS3
dehydrogenase/reductase 3
chr19_-_10380558 1.99 ENST00000524462.5
ENST00000525621.6
ENST00000531836.5
TYK2
tyrosine kinase 2
chr11_-_57410113 1.43 ENST00000529411.1
ENSG00000254979.5
novel protein
chr19_+_3762665 1.32 ENST00000330133.5
MRPL54
mitochondrial ribosomal protein L54
chr3_-_190122317 1.32 ENST00000427335.6
P3H2
prolyl 3-hydroxylase 2
chr1_+_65147657 1.17 ENST00000546702.5
AK4
adenylate kinase 4
chr2_-_162318475 1.16 ENST00000648433.1
IFIH1
interferon induced with helicase C domain 1
chr5_-_16916400 1.10 ENST00000513882.5
MYO10
myosin X
chr7_-_106285898 1.08 ENST00000424768.2
ENST00000681255.1
NAMPT
nicotinamide phosphoribosyltransferase
chr18_+_24139053 1.06 ENST00000463087.5
ENST00000585037.5
ENST00000399496.8
ENST00000486759.6
ENST00000577705.1
ENST00000415309.6
ENST00000621648.4
ENST00000581397.5
CABYR
calcium binding tyrosine phosphorylation regulated
chr9_-_2844058 0.90 ENST00000397885.3
PUM3
pumilio RNA binding family member 3
chr2_+_233388146 0.85 ENST00000409813.7
DGKD
diacylglycerol kinase delta
chr2_-_119366757 0.85 ENST00000414534.1
C2orf76
chromosome 2 open reading frame 76
chr20_+_33217325 0.79 ENST00000375452.3
ENST00000375454.8
BPIFA3
BPI fold containing family A member 3
chr10_-_90921079 0.77 ENST00000371697.4
ANKRD1
ankyrin repeat domain 1
chr11_-_76670737 0.75 ENST00000260061.9
ENST00000404995.5
LRRC32
leucine rich repeat containing 32
chr1_+_65147514 0.74 ENST00000545314.5
AK4
adenylate kinase 4
chr4_+_155758990 0.69 ENST00000505154.5
ENST00000652626.1
ENST00000502959.5
ENST00000264424.13
ENST00000505764.5
ENST00000507146.5
ENST00000503520.5
GUCY1B1
guanylate cyclase 1 soluble subunit beta 1
chr2_+_11724333 0.67 ENST00000425416.6
ENST00000396097.5
LPIN1
lipin 1
chr19_+_3762705 0.66 ENST00000589174.1
MRPL54
mitochondrial ribosomal protein L54
chr3_-_16482850 0.66 ENST00000432519.5
RFTN1
raftlin, lipid raft linker 1
chr9_-_83267230 0.64 ENST00000328788.5
FRMD3
FERM domain containing 3
chr2_-_162318613 0.64 ENST00000649979.2
ENST00000421365.2
IFIH1
interferon induced with helicase C domain 1
chr11_-_113706330 0.61 ENST00000540540.5
ENST00000538955.5
ENST00000545579.6
TMPRSS5
transmembrane serine protease 5
chr10_-_43397220 0.58 ENST00000477108.5
ENST00000544000.5
HNRNPF
heterogeneous nuclear ribonucleoprotein F
chr11_-_113706292 0.57 ENST00000544634.5
ENST00000539732.5
ENST00000538770.1
ENST00000536856.5
ENST00000299882.11
ENST00000544476.1
TMPRSS5
transmembrane serine protease 5
chr11_-_76669985 0.56 ENST00000407242.6
ENST00000421973.1
LRRC32
leucine rich repeat containing 32
chr20_-_23605917 0.52 ENST00000376971.4
CST9
cystatin 9
chr3_+_128051610 0.52 ENST00000464451.5
SEC61A1
SEC61 translocon subunit alpha 1
chr14_-_24609660 0.51 ENST00000557220.6
ENST00000216338.9
ENST00000382548.4
GZMH
granzyme H
chr12_+_9827472 0.50 ENST00000617793.4
ENST00000617889.5
ENST00000354855.7
ENST00000279545.7
KLRF1
killer cell lectin like receptor F1
chrX_+_11111291 0.50 ENST00000321143.8
ENST00000380762.5
ENST00000380763.7
HCCS
holocytochrome c synthase
chr11_-_133845495 0.50 ENST00000299140.8
ENST00000532889.1
SPATA19
spermatogenesis associated 19
chr3_-_58627596 0.49 ENST00000474531.5
ENST00000465970.1
FAM107A
family with sequence similarity 107 member A
chr1_-_144456805 0.48 ENST00000581897.6
ENST00000577412.5
NBPF15
NBPF member 15
chr10_-_72216267 0.47 ENST00000342444.8
ENST00000533958.1
ENST00000672957.1
ENST00000527593.5
ENST00000672940.1
ENST00000530461.5
ENST00000317168.11
ENST00000524829.5
ASCC1
activating signal cointegrator 1 complex subunit 1
chr13_+_108596152 0.46 ENST00000356711.7
ENST00000251041.10
MYO16
myosin XVI
chr1_-_183653307 0.45 ENST00000308641.6
APOBEC4
apolipoprotein B mRNA editing enzyme catalytic polypeptide like 4
chr20_-_14337602 0.45 ENST00000378053.3
ENST00000341420.5
FLRT3
fibronectin leucine rich transmembrane protein 3
chr15_+_59611776 0.44 ENST00000396065.3
ENST00000560585.5
GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr17_-_69150062 0.43 ENST00000522787.5
ENST00000521538.5
ABCA10
ATP binding cassette subfamily A member 10
chr10_-_13972355 0.42 ENST00000264546.10
FRMD4A
FERM domain containing 4A
chr4_-_170003738 0.42 ENST00000502832.1
ENST00000393704.3
MFAP3L
microfibril associated protein 3 like
chr1_-_200410001 0.42 ENST00000367353.2
ZNF281
zinc finger protein 281
chr19_+_17719471 0.40 ENST00000600186.5
ENST00000597735.5
ENST00000324096.9
MAP1S
microtubule associated protein 1S
chr11_+_4704782 0.37 ENST00000380390.6
MMP26
matrix metallopeptidase 26
chr20_+_50958805 0.37 ENST00000244051.3
MOCS3
molybdenum cofactor synthesis 3
chr1_+_152985231 0.35 ENST00000368762.1
SPRR1A
small proline rich protein 1A
chr2_-_208190001 0.35 ENST00000451346.5
ENST00000341287.9
C2orf80
chromosome 2 open reading frame 80
chr6_+_28281555 0.35 ENST00000259883.3
ENST00000682144.1
PGBD1
piggyBac transposable element derived 1
chr10_-_72217126 0.35 ENST00000317126.8
ASCC1
activating signal cointegrator 1 complex subunit 1
chr9_-_120876356 0.34 ENST00000456291.1
PHF19
PHD finger protein 19
chr1_-_200410052 0.32 ENST00000294740.3
ZNF281
zinc finger protein 281
chr12_+_92702843 0.28 ENST00000397833.3
PLEKHG7
pleckstrin homology and RhoGEF domain containing G7
chr19_+_51761167 0.27 ENST00000340023.7
ENST00000599326.1
ENST00000598953.1
FPR2
formyl peptide receptor 2
chrX_-_56995426 0.27 ENST00000640768.1
ENST00000638619.1
SPIN3
spindlin family member 3
chr22_-_30266839 0.26 ENST00000403463.1
ENST00000215781.3
OSM
oncostatin M
chr11_+_62242232 0.26 ENST00000244926.4
SCGB1D2
secretoglobin family 1D member 2
chr1_-_200409976 0.25 ENST00000367352.3
ZNF281
zinc finger protein 281
chr1_-_52033772 0.25 ENST00000371614.2
KTI12
KTI12 chromatin associated homolog
chr11_-_26572130 0.24 ENST00000527569.1
MUC15
mucin 15, cell surface associated
chr6_-_130222813 0.23 ENST00000437477.6
ENST00000439090.7
SAMD3
sterile alpha motif domain containing 3
chrX_-_56995508 0.23 ENST00000374919.6
ENST00000639007.1
ENST00000639583.1
ENST00000638289.1
ENST00000639525.1
ENST00000638386.1
SPIN3
spindlin family member 3
chr14_-_73950393 0.23 ENST00000651776.1
FAM161B
FAM161 centrosomal protein B
chr3_+_178558700 0.22 ENST00000432997.5
ENST00000455865.5
KCNMB2
potassium calcium-activated channel subfamily M regulatory beta subunit 2
chr1_-_43172504 0.22 ENST00000431635.6
EBNA1BP2
EBNA1 binding protein 2
chr5_-_173616588 0.21 ENST00000285908.5
ENST00000311086.9
ENST00000480951.1
BOD1
biorientation of chromosomes in cell division 1
chr17_-_31297231 0.20 ENST00000247271.5
OMG
oligodendrocyte myelin glycoprotein
chr17_-_4641670 0.20 ENST00000293761.8
ALOX15
arachidonate 15-lipoxygenase
chrX_+_129906146 0.20 ENST00000394422.8
UTP14A
UTP14A small subunit processome component
chr1_+_84479239 0.19 ENST00000370656.5
ENST00000370654.6
RPF1
ribosome production factor 1 homolog
chr6_-_70957029 0.19 ENST00000230053.11
B3GAT2
beta-1,3-glucuronyltransferase 2
chr1_+_174799895 0.18 ENST00000489615.5
RABGAP1L
RAB GTPase activating protein 1 like
chr17_-_40665121 0.17 ENST00000394052.5
KRT222
keratin 222
chr8_-_92017292 0.17 ENST00000521553.5
RUNX1T1
RUNX1 partner transcriptional co-repressor 1
chr19_+_49085433 0.17 ENST00000221448.9
ENST00000598441.6
SNRNP70
small nuclear ribonucleoprotein U1 subunit 70
chr3_+_138608575 0.16 ENST00000338446.8
FAIM
Fas apoptotic inhibitory molecule
chr1_+_240091866 0.16 ENST00000319653.14
FMN2
formin 2
chr2_+_201116396 0.15 ENST00000395148.6
CFLAR
CASP8 and FADD like apoptosis regulator
chr1_+_203795614 0.15 ENST00000367210.3
ENST00000432282.5
ENST00000453771.5
ENST00000367214.5
ENST00000639812.1
ENST00000367212.7
ENST00000332127.8
ENST00000550078.2
ZC3H11A
ZBED6
zinc finger CCCH-type containing 11A
zinc finger BED-type containing 6
chr3_+_138608700 0.14 ENST00000360570.7
FAIM
Fas apoptotic inhibitory molecule
chr3_+_138608851 0.14 ENST00000393035.6
FAIM
Fas apoptotic inhibitory molecule
chr15_+_75903893 0.14 ENST00000565036.5
ENST00000569054.5
FBXO22
F-box protein 22
chrX_+_129906118 0.13 ENST00000425117.6
UTP14A
UTP14A small subunit processome component
chr16_+_11965193 0.13 ENST00000053243.6
ENST00000396495.3
TNFRSF17
TNF receptor superfamily member 17
chr10_+_76318330 0.13 ENST00000496424.2
LRMDA
leucine rich melanocyte differentiation associated
chr1_-_86383078 0.12 ENST00000460698.6
ODF2L
outer dense fiber of sperm tails 2 like
chr17_-_15265230 0.12 ENST00000676161.1
ENST00000646419.2
ENST00000312280.9
ENST00000494511.7
ENST00000580584.3
ENST00000676221.1
PMP22
peripheral myelin protein 22
chr7_+_142749465 0.11 ENST00000486171.5
ENST00000619214.4
ENST00000311737.12
PRSS1
serine protease 1
chr10_+_93993897 0.11 ENST00000371380.8
PLCE1
phospholipase C epsilon 1
chr12_-_10454485 0.11 ENST00000408006.7
ENST00000544822.2
ENST00000536188.5
KLRC1
killer cell lectin like receptor C1
chr11_-_26572102 0.10 ENST00000455601.6
MUC15
mucin 15, cell surface associated
chr10_-_95069489 0.10 ENST00000371270.6
ENST00000535898.5
ENST00000623108.3
CYP2C8
cytochrome P450 family 2 subfamily C member 8
chrX_-_120878924 0.10 ENST00000613352.1
ENSG00000278646.1
novel protein similar to cancer/testis antigen family 47, member A12 (CT47A12)
chr1_+_12746192 0.10 ENST00000614859.5
C1orf158
chromosome 1 open reading frame 158
chr20_-_50958520 0.09 ENST00000371588.10
ENST00000371584.9
ENST00000413082.1
ENST00000371582.8
DPM1
dolichyl-phosphate mannosyltransferase subunit 1, catalytic
chr3_-_185938006 0.08 ENST00000342294.4
ENST00000453386.7
ENST00000382191.4
TRA2B
transformer 2 beta homolog
chr6_+_26183750 0.08 ENST00000614097.3
H2BC6
H2B clustered histone 6
chr2_+_101998955 0.07 ENST00000393414.6
IL1R2
interleukin 1 receptor type 2
chr17_+_77185210 0.07 ENST00000431431.6
SEC14L1
SEC14 like lipid binding 1
chr18_-_54224578 0.07 ENST00000583046.1
ENST00000398398.6
ENST00000256429.8
MBD2
methyl-CpG binding domain protein 2
chr7_-_93219545 0.07 ENST00000440868.5
HEPACAM2
HEPACAM family member 2
chr7_-_93219564 0.06 ENST00000341723.8
HEPACAM2
HEPACAM family member 2
chr4_-_141212877 0.06 ENST00000420921.6
RNF150
ring finger protein 150
chr20_-_45667177 0.06 ENST00000618797.4
WFDC11
WAP four-disulfide core domain 11
chr11_-_47378391 0.06 ENST00000227163.8
SPI1
Spi-1 proto-oncogene
chr1_-_111563934 0.06 ENST00000443498.5
TMIGD3
transmembrane and immunoglobulin domain containing 3
chr14_-_60165363 0.06 ENST00000557185.6
DHRS7
dehydrogenase/reductase 7
chr7_-_43869491 0.05 ENST00000317534.6
ENST00000418740.5
MRPS24
mitochondrial ribosomal protein S24
chr7_-_105389365 0.05 ENST00000482897.5
SRPK2
SRSF protein kinase 2
chr15_+_40382715 0.05 ENST00000416151.6
ENST00000249776.12
KNSTRN
kinetochore localized astrin (SPAG5) binding protein
chr11_-_47378494 0.04 ENST00000533030.1
SPI1
Spi-1 proto-oncogene
chr20_-_50131125 0.04 ENST00000371656.3
PEDS1
plasmanylethanolamine desaturase 1
chr11_+_125626229 0.04 ENST00000532449.6
ENST00000534070.5
CHEK1
checkpoint kinase 1
chr15_-_45114149 0.04 ENST00000603300.1
ENST00000389039.11
DUOX2
dual oxidase 2
chr17_-_17281232 0.04 ENST00000417352.5
ENST00000268717.10
COPS3
COP9 signalosome subunit 3
chr3_+_11011640 0.04 ENST00000643396.1
SLC6A1
solute carrier family 6 member 1
chr19_+_54874218 0.03 ENST00000355524.8
ENST00000391726.7
FCAR
Fc fragment of IgA receptor
chrX_-_72877864 0.02 ENST00000596389.5
DMRTC1
DMRT like family C1
chr16_-_11782552 0.02 ENST00000396516.6
ZC3H7A
zinc finger CCCH-type containing 7A
chr2_+_170178136 0.02 ENST00000409044.7
ENST00000408978.9
MYO3B
myosin IIIB
chr4_-_73620629 0.02 ENST00000342081.7
RASSF6
Ras association domain family member 6
chr14_-_20333268 0.02 ENST00000358932.9
ENST00000557665.5
CCNB1IP1
cyclin B1 interacting protein 1
chr3_+_136957948 0.02 ENST00000329582.9
IL20RB
interleukin 20 receptor subunit beta
chr14_-_20333306 0.02 ENST00000353689.8
ENST00000437553.6
CCNB1IP1
cyclin B1 interacting protein 1
chr17_-_81166160 0.02 ENST00000326724.9
AATK
apoptosis associated tyrosine kinase
chr3_+_174859315 0.01 ENST00000454872.6
NAALADL2
N-acetylated alpha-linked acidic dipeptidase like 2
chr17_+_36064265 0.01 ENST00000616054.2
CCL18
C-C motif chemokine ligand 18
chrX_-_116462965 0.00 ENST00000371894.5
CT83
cancer/testis antigen 83
chr3_-_33645433 0.00 ENST00000635664.1
ENST00000485378.6
ENST00000313350.10
ENST00000487200.5
CLASP2
cytoplasmic linker associated protein 2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 4.5 GO:0034344 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.1 2.4 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1 1.9 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.1 0.4 GO:0018307 enzyme active site formation(GO:0018307)
0.1 0.7 GO:0006642 triglyceride mobilization(GO:0006642)
0.1 0.9 GO:0010835 regulation of protein ADP-ribosylation(GO:0010835)
0.1 0.5 GO:0039019 pronephric nephron development(GO:0039019)
0.1 0.7 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.1 1.3 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.1 0.2 GO:2001302 regulation of engulfment of apoptotic cell(GO:1901074) lipoxin biosynthetic process(GO:2001301) lipoxin A4 metabolic process(GO:2001302) lipoxin A4 biosynthetic process(GO:2001303)
0.1 0.8 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.1 1.3 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.0 1.1 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.0 0.2 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.0 0.3 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.0 0.8 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 1.1 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.3 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.0 0.4 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.2 GO:0061084 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.0 1.0 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.5 GO:0003344 pericardium morphogenesis(GO:0003344)
0.0 1.0 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.0 0.1 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.0 0.3 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.0 GO:0048850 hypophysis morphogenesis(GO:0048850)
0.0 0.1 GO:0032690 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.0 2.0 GO:0070126 mitochondrial translational termination(GO:0070126)
0.0 0.1 GO:0002933 lipid hydroxylation(GO:0002933)
0.0 1.0 GO:0060338 regulation of type I interferon-mediated signaling pathway(GO:0060338)
0.0 0.1 GO:0019348 dolichol metabolic process(GO:0019348)
0.0 0.1 GO:1903943 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 1.1 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 0.4 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.5 GO:0017004 cytochrome complex assembly(GO:0017004)
0.0 0.0 GO:0051939 gamma-aminobutyric acid import(GO:0051939)
0.0 0.2 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.0 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:0097229 sperm end piece(GO:0097229)
0.1 2.4 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 1.1 GO:0032433 filopodium tip(GO:0032433)
0.0 0.1 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0 2.0 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.2 GO:0000243 commitment complex(GO:0000243)
0.0 0.5 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.4 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.3 GO:0035098 ESC/E(Z) complex(GO:0035098)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.9 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.3 1.3 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797)
0.3 0.8 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.2 1.1 GO:0047280 nicotinamide phosphoribosyltransferase activity(GO:0047280)
0.2 2.4 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 0.4 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.1 1.1 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.1 0.4 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.1 1.0 GO:0005131 growth hormone receptor binding(GO:0005131)
0.1 0.3 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.1 0.2 GO:0047977 hepoxilin-epoxide hydrolase activity(GO:0047977)
0.0 0.2 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.0 0.8 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.2 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.5 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 5.1 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.7 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.1 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0 0.2 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 0.1 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.0 0.1 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0 0.5 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.3 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.1 GO:0035197 siRNA binding(GO:0035197)
0.0 1.4 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.1 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.0 0.6 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.1 GO:0039552 RIG-I binding(GO:0039552)
0.0 0.0 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 2.4 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.1 PID NETRIN PATHWAY Netrin-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.5 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.1 1.0 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.7 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.8 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.4 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 1.1 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling