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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for SOX13_SOX12

Z-value: 0.74

Motif logo

Transcription factors associated with SOX13_SOX12

Gene Symbol Gene ID Gene Info
ENSG00000143842.15 SOX13
ENSG00000177732.9 SOX12

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX12hg38_v1_chr20_+_325536_325565-0.213.1e-01Click!
SOX13hg38_v1_chr1_+_204073104_204073121-0.087.2e-01Click!

Activity profile of SOX13_SOX12 motif

Sorted Z-values of SOX13_SOX12 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX13_SOX12

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr1_+_78620722 1.63 ENST00000679848.1
interferon induced protein 44 like
chr3_-_132684685 1.32 ENST00000512094.5
ENST00000632629.1
nephrocystin 3
NPHP3-ACAD11 readthrough (NMD candidate)
chr2_-_201697993 1.25 ENST00000428900.6
membrane palmitoylated protein 4
chr12_+_77830886 1.24 ENST00000397909.7
ENST00000549464.5
neuron navigator 3
chr2_-_201698040 1.22 ENST00000396886.7
ENST00000409143.5
membrane palmitoylated protein 4
chr17_+_43006740 1.09 ENST00000438323.2
ENST00000415816.7
interferon induced protein 35
chr18_-_72544336 1.08 ENST00000269503.9
cerebellin 2 precursor
chr7_-_115968302 1.01 ENST00000457268.5
transcription factor EC
chr2_+_102311502 1.01 ENST00000404917.6
ENST00000410040.5
interleukin 1 receptor like 1
interleukin 18 receptor 1
chr21_-_14658812 0.95 ENST00000647101.1
SAM domain, SH3 domain and nuclear localization signals 1
chr6_-_89217339 0.94 ENST00000454853.7
gamma-aminobutyric acid type A receptor subunit rho1
chr2_-_201698628 0.84 ENST00000602867.1
ENST00000409474.8
membrane palmitoylated protein 4
chr2_-_201698692 0.82 ENST00000315506.11
ENST00000359962.9
ENST00000620095.4
membrane palmitoylated protein 4
chr2_+_167135901 0.78 ENST00000628543.2
xin actin binding repeat containing 2
chr10_+_68106109 0.77 ENST00000540630.5
ENST00000354393.6
myopalladin
chr19_+_21082140 0.77 ENST00000616183.1
ENST00000596053.5
zinc finger protein 714
chr8_-_13276491 0.73 ENST00000512044.6
DLC1 Rho GTPase activating protein
chr8_-_13514744 0.73 ENST00000316609.9
DLC1 Rho GTPase activating protein
chr11_+_55262152 0.71 ENST00000417545.5
tripartite motif containing 48
chr4_+_94207596 0.70 ENST00000359052.8
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr5_+_157269317 0.69 ENST00000618329.4
cytoplasmic FMR1 interacting protein 2
chr1_-_243255170 0.69 ENST00000366542.6
centrosomal protein 170
chr18_+_74534594 0.66 ENST00000582365.1
carnosine dipeptidase 1
chr6_-_25830557 0.65 ENST00000468082.1
solute carrier family 17 member 1
chr4_+_94207845 0.65 ENST00000457823.6
ENST00000354268.9
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr1_-_243255320 0.64 ENST00000366544.5
ENST00000366543.5
centrosomal protein 170
chr17_-_69244846 0.63 ENST00000269081.8
ATP binding cassette subfamily A member 10
chr17_+_55751021 0.62 ENST00000268896.10
ENST00000576183.5
ENST00000573500.5
phosphatidylcholine transfer protein
chr11_+_5689780 0.60 ENST00000379965.8
ENST00000454828.5
tripartite motif containing 22
chr1_+_244352627 0.60 ENST00000366537.5
ENST00000308105.5
chromosome 1 open reading frame 100
chr9_-_21351378 0.59 ENST00000380210.1
interferon alpha 6
chr6_-_134318097 0.57 ENST00000367858.10
ENST00000533224.1
serum/glucocorticoid regulated kinase 1
chr5_+_122129533 0.57 ENST00000296600.5
ENST00000504912.1
ENST00000505843.1
zinc finger protein 474
chr6_-_128520358 0.56 ENST00000368215.7
ENST00000532331.5
ENST00000368213.9
ENST00000368207.7
ENST00000525459.1
ENST00000368226.9
ENST00000368210.7
protein tyrosine phosphatase receptor type K
chr11_-_55936400 0.56 ENST00000301532.3
olfactory receptor family 5 subfamily I member 1
chr6_-_112087451 0.56 ENST00000368662.10
tubulin epsilon 1
chr3_-_123620496 0.55 ENST00000578202.1
myosin light chain kinase
chr6_-_11778781 0.55 ENST00000414691.8
ENST00000229583.9
androgen dependent TFPI regulating protein
chr7_-_47582076 0.55 ENST00000311160.14
tensin 3
chr15_+_94355956 0.53 ENST00000557742.1
multiple C2 and transmembrane domain containing 2
chr10_+_68721012 0.53 ENST00000536391.5
ENST00000630771.2
cell division cycle and apoptosis regulator 1
chr11_-_102780620 0.53 ENST00000279441.9
ENST00000539681.1
matrix metallopeptidase 10
chr18_+_74534493 0.52 ENST00000358821.8
carnosine dipeptidase 1
chr5_+_35856883 0.52 ENST00000506850.5
ENST00000303115.8
ENST00000511982.1
interleukin 7 receptor
chr4_+_87832917 0.50 ENST00000395102.8
ENST00000497649.6
ENST00000540395.1
ENST00000560249.5
ENST00000511670.5
ENST00000361056.3
matrix extracellular phosphoglycoprotein
chr19_+_926001 0.50 ENST00000263620.8
AT-rich interaction domain 3A
chr2_+_167187283 0.47 ENST00000409605.1
ENST00000409273.6
xin actin binding repeat containing 2
chr11_+_93746433 0.47 ENST00000526335.1
chromosome 11 open reading frame 54
chr5_-_124745315 0.46 ENST00000306315.9
zinc finger protein 608
chr2_-_216013517 0.46 ENST00000263268.11
melanoregulin
chr7_-_41703062 0.46 ENST00000242208.5
inhibin subunit beta A
chr11_+_7088991 0.46 ENST00000306904.7
RBMX like 2
chr6_+_26402237 0.45 ENST00000476549.6
ENST00000450085.6
ENST00000425234.6
ENST00000427334.5
ENST00000506698.1
ENST00000289361.11
butyrophilin subfamily 3 member A1
chr5_-_97183203 0.43 ENST00000508447.1
ENST00000283109.8
RIO kinase 2
chr8_-_63026179 0.42 ENST00000677919.1
gamma-glutamyl hydrolase
chr9_-_6565462 0.42 ENST00000638661.1
ENST00000640208.1
glycine decarboxylase
chr3_-_49929800 0.42 ENST00000455683.6
MON1 homolog A, secretory trafficking associated
chr5_-_75717368 0.41 ENST00000514838.6
ENST00000506164.5
ENST00000502826.5
ENST00000428202.7
ENST00000503835.5
POC5 centriolar protein
chr11_-_89921767 0.41 ENST00000530311.6
tripartite motif containing 49D1
chr8_+_116938180 0.41 ENST00000378279.4
alanine and arginine rich domain containing protein
chr1_-_11796536 0.40 ENST00000641820.1
methylenetetrahydrofolate reductase
chr8_-_124728273 0.40 ENST00000325064.9
ENST00000518547.6
MTSS I-BAR domain containing 1
chr6_+_26440472 0.40 ENST00000494393.5
ENST00000482451.5
ENST00000471353.5
ENST00000361232.7
ENST00000487627.5
ENST00000496719.1
ENST00000244519.7
ENST00000490254.5
ENST00000487272.1
butyrophilin subfamily 3 member A3
chr15_-_79971164 0.39 ENST00000335661.6
ENST00000267953.4
ENST00000677151.1
BCL2 related protein A1
chr1_-_7940825 0.39 ENST00000377507.8
TNF receptor superfamily member 9
chr9_+_5510492 0.38 ENST00000397747.5
programmed cell death 1 ligand 2
chr10_+_116545907 0.38 ENST00000369221.2
pancreatic lipase
chr8_+_24294044 0.38 ENST00000265769.9
ADAM metallopeptidase domain 28
chr5_+_40841308 0.37 ENST00000381677.4
ENST00000254691.10
caspase recruitment domain family member 6
chr3_+_40477107 0.37 ENST00000314686.9
ENST00000447116.6
ENST00000429348.6
ENST00000432264.4
ENST00000456778.5
zinc finger protein 619
chr12_-_7444139 0.36 ENST00000416109.2
ENST00000313599.8
CD163 molecule like 1
chr5_+_55024250 0.36 ENST00000231009.3
granzyme K
chr3_+_155079663 0.35 ENST00000460393.6
membrane metalloendopeptidase
chr14_+_94110728 0.35 ENST00000616764.4
ENST00000618863.1
ENST00000611954.4
ENST00000618200.4
ENST00000621160.4
ENST00000555819.5
ENST00000620396.4
ENST00000612813.4
ENST00000620066.1
interferon alpha inducible protein 27
chr3_-_142448060 0.35 ENST00000264951.8
5'-3' exoribonuclease 1
chr21_-_30497160 0.35 ENST00000334058.3
keratin associated protein 19-4
chr16_-_53052849 0.35 ENST00000619363.2
novel protein
chr15_-_40874216 0.34 ENST00000220507.5
ras homolog family member V
chr2_+_102418642 0.34 ENST00000264260.6
interleukin 18 receptor accessory protein
chr18_+_46917561 0.34 ENST00000683218.1
katanin catalytic subunit A1 like 2
chr6_+_116399395 0.33 ENST00000644499.1
novel protein
chr4_-_83010709 0.33 ENST00000506560.5
ENST00000442461.6
ENST00000340417.8
ENST00000446851.6
lin-54 DREAM MuvB core complex component
chr7_+_64794388 0.33 ENST00000359735.7
zinc finger protein 138
chr5_+_136132772 0.33 ENST00000545279.6
ENST00000507118.5
ENST00000511116.5
ENST00000545620.5
ENST00000509297.6
SMAD family member 5
chr2_-_89085787 0.33 ENST00000390252.2
immunoglobulin kappa variable 3-15
chr5_+_140855882 0.33 ENST00000562220.2
ENST00000307360.6
ENST00000506939.6
protocadherin alpha 10
chr3_+_141876124 0.33 ENST00000475483.5
ATPase Na+/K+ transporting subunit beta 3
chr2_-_150487658 0.33 ENST00000375734.6
ENST00000263895.9
ENST00000454202.5
Rho family GTPase 3
chr6_-_118935146 0.33 ENST00000619706.5
ENST00000316316.10
minichromosome maintenance 9 homologous recombination repair factor
chr22_+_35648438 0.33 ENST00000409652.5
apolipoprotein L6
chr13_-_41132728 0.33 ENST00000379485.2
kelch repeat and BTB domain containing 6
chr7_-_64982021 0.32 ENST00000610793.1
ENST00000620222.4
zinc finger protein 117
chr6_+_127577168 0.32 ENST00000329722.8
chromosome 6 open reading frame 58
chr11_+_35180279 0.32 ENST00000531873.5
CD44 molecule (Indian blood group)
chr2_-_240820945 0.32 ENST00000428768.2
ENST00000650053.1
ENST00000650130.1
kinesin family member 1A
chr12_-_42483958 0.32 ENST00000548696.6
ENST00000552240.6
prickle planar cell polarity protein 1
chr22_+_18150162 0.32 ENST00000215794.8
ubiquitin specific peptidase 18
chr11_-_85719045 0.31 ENST00000533057.6
ENST00000533892.5
synaptotagmin like 2
chr3_-_108058361 0.30 ENST00000398258.7
CD47 molecule
chr11_+_35180342 0.30 ENST00000639002.1
CD44 molecule (Indian blood group)
chr4_+_70050431 0.30 ENST00000511674.5
ENST00000246896.8
histatin 1
chr18_-_22417910 0.30 ENST00000391403.4
cutaneous T cell lymphoma-associated antigen 1
chr14_-_52069039 0.30 ENST00000216286.10
nidogen 2
chr11_-_85719160 0.30 ENST00000389958.7
ENST00000527794.5
synaptotagmin like 2
chr2_-_216013582 0.30 ENST00000620139.4
melanoregulin
chr5_-_20575850 0.29 ENST00000507958.5
cadherin 18
chr11_-_89922245 0.29 ENST00000420869.3
tripartite motif containing 49D1
chr1_+_206635521 0.29 ENST00000367109.8
dual specificity tyrosine phosphorylation regulated kinase 3
chr2_+_167187364 0.29 ENST00000672671.1
xin actin binding repeat containing 2
chr19_-_9219589 0.28 ENST00000641244.1
ENST00000641669.1
olfactory receptor family 7 subfamily D member 4
chr9_-_28670285 0.28 ENST00000379992.6
ENST00000308675.5
ENST00000613945.3
leucine rich repeat and Ig domain containing 2
chr17_-_81937221 0.28 ENST00000402252.6
ENST00000583564.5
ENST00000585244.1
ENST00000337943.9
ENST00000579698.5
pyrroline-5-carboxylate reductase 1
chr12_-_42484298 0.28 ENST00000640055.1
ENST00000639566.1
ENST00000455697.6
ENST00000639589.1
prickle planar cell polarity protein 1
chr14_+_96482982 0.28 ENST00000554706.1
adenylate kinase 7
chr19_+_21505585 0.28 ENST00000358491.9
ENST00000597078.5
zinc finger protein 429
chr14_+_36657560 0.28 ENST00000402703.6
paired box 9
chr19_-_55140922 0.28 ENST00000589745.5
troponin T1, slow skeletal type
chr2_-_68952880 0.27 ENST00000481498.1
ENST00000328895.9
gastrokine 2
chr6_+_42782020 0.27 ENST00000314073.9
BRD4 interacting chromatin remodeling complex associated protein like
chr2_+_118942188 0.27 ENST00000327097.5
macrophage receptor with collagenous structure
chr10_-_59753388 0.27 ENST00000430431.5
myoregulin
chr6_+_122399536 0.27 ENST00000452194.5
heat shock transcription factor 2
chr1_-_158686700 0.27 ENST00000643759.2
spectrin alpha, erythrocytic 1
chr2_+_57907621 0.27 ENST00000648897.1
ENST00000435505.6
ENST00000417641.6
VRK serine/threonine kinase 2
chr3_-_179259208 0.27 ENST00000485523.5
potassium calcium-activated channel subfamily M regulatory beta subunit 3
chr17_-_81937277 0.27 ENST00000405481.8
ENST00000329875.13
ENST00000585215.5
pyrroline-5-carboxylate reductase 1
chr19_+_21505656 0.26 ENST00000618549.1
zinc finger protein 429
chr4_+_99511008 0.26 ENST00000514652.5
ENST00000326581.9
chromosome 4 open reading frame 17
chr1_-_92792396 0.26 ENST00000370331.5
ENST00000540033.2
ecotropic viral integration site 5
chr11_+_96389985 0.26 ENST00000332349.5
JRK like
chr7_+_64794415 0.25 ENST00000494380.5
ENST00000440155.6
ENST00000440598.2
ENST00000437743.1
ENST00000307355.12
zinc finger protein 138
chr19_+_20923222 0.25 ENST00000597314.5
ENST00000328178.13
ENST00000601924.5
zinc finger protein 85
chr1_+_172420681 0.25 ENST00000367727.9
chromosome 1 open reading frame 105
chr19_+_21082190 0.25 ENST00000618422.1
ENST00000618008.4
ENST00000425625.5
ENST00000456283.7
zinc finger protein 714
chr1_-_247758680 0.25 ENST00000408896.4
olfactory receptor family 1 subfamily C member 1
chr4_+_164754116 0.25 ENST00000507311.1
small integral membrane protein 31
chr7_-_131556602 0.25 ENST00000322985.9
ENST00000378555.8
podocalyxin like
chr15_-_88546585 0.25 ENST00000649547.1
ENST00000558413.1
ENST00000564406.5
ENST00000268148.13
novel transcript
DET1 partner of COP1 E3 ubiquitin ligase
chr17_-_81937320 0.25 ENST00000577624.5
ENST00000403172.8
ENST00000619204.4
ENST00000629768.2
pyrroline-5-carboxylate reductase 1
chr18_+_34593392 0.25 ENST00000684377.1
dystrobrevin alpha
chr11_-_89920428 0.25 ENST00000605881.5
tripartite motif containing 49D1
chr6_+_113857333 0.24 ENST00000612661.2
myristoylated alanine rich protein kinase C substrate
chr3_+_171843337 0.24 ENST00000334567.9
ENST00000619900.4
ENST00000450693.1
transmembrane protein 212
chr4_-_121164314 0.24 ENST00000057513.8
TNFAIP3 interacting protein 3
chr11_+_131911396 0.24 ENST00000425719.6
ENST00000374784.5
neurotrimin
chr2_+_196713117 0.24 ENST00000409270.5
coiled-coil domain containing 150
chr8_-_42501224 0.24 ENST00000520262.6
ENST00000517366.1
solute carrier family 20 member 2
chr4_-_56681288 0.24 ENST00000556376.6
ENST00000420433.6
HOP homeobox
chr1_-_153041111 0.24 ENST00000360379.4
small proline rich protein 2D
chr15_-_89211803 0.23 ENST00000563254.1
retinaldehyde binding protein 1
chr11_-_85719111 0.23 ENST00000529581.5
ENST00000533577.1
synaptotagmin like 2
chr2_+_33436304 0.23 ENST00000402538.7
RAS guanyl releasing protein 3
chr7_+_138460400 0.23 ENST00000415680.6
tripartite motif containing 24
chr19_+_21142024 0.23 ENST00000600692.5
ENST00000599296.5
ENST00000594425.5
ENST00000311048.11
zinc finger protein 431
chrX_-_32155462 0.23 ENST00000359836.5
ENST00000378707.7
ENST00000541735.5
ENST00000684130.1
ENST00000682238.1
ENST00000620040.5
ENST00000474231.5
dystrophin
chr15_+_36594868 0.23 ENST00000566807.5
ENST00000643612.1
ENST00000567389.5
ENST00000562877.5
CDAN1 interacting nuclease 1
chr3_+_32391871 0.22 ENST00000465248.1
CKLF like MARVEL transmembrane domain containing 7
chr18_+_34593312 0.22 ENST00000591816.6
ENST00000588125.5
ENST00000684610.1
ENST00000683705.1
ENST00000598334.5
ENST00000588684.5
ENST00000554864.7
ENST00000399121.9
ENST00000595022.5
dystrobrevin alpha
chr11_+_60455839 0.22 ENST00000532491.5
ENST00000532073.5
ENST00000345732.9
ENST00000534668.6
ENST00000528313.1
ENST00000533306.6
ENST00000674194.1
membrane spanning 4-domains A1
chr3_+_32391841 0.22 ENST00000334983.10
CKLF like MARVEL transmembrane domain containing 7
chr11_+_35176575 0.22 ENST00000526000.6
CD44 molecule (Indian blood group)
chr1_+_162069768 0.22 ENST00000530878.5
nitric oxide synthase 1 adaptor protein
chr3_+_32391694 0.21 ENST00000349718.8
CKLF like MARVEL transmembrane domain containing 7
chr12_-_11134644 0.21 ENST00000539585.1
taste 2 receptor member 30
chr9_+_68780029 0.21 ENST00000394264.7
PP2A Aalpha (PPP2R1A) and B55A (PPP2R2A) interacting phosphatase regulator 1
chr11_+_6845683 0.21 ENST00000299454.5
olfactory receptor family 10 subfamily A member 5
chr10_-_104085847 0.21 ENST00000648076.2
collagen type XVII alpha 1 chain
chr6_+_122996227 0.21 ENST00000275162.10
clavesin 2
chr18_-_5540515 0.21 ENST00000544123.5
ENST00000585142.5
erythrocyte membrane protein band 4.1 like 3
chr2_+_206939515 0.21 ENST00000272852.4
carboxypeptidase O
chr5_-_160852200 0.20 ENST00000327245.10
ATPase phospholipid transporting 10B (putative)
chr11_-_5324297 0.20 ENST00000624187.1
olfactory receptor family 51 subfamily B member 2
chr10_-_59753444 0.20 ENST00000594536.5
ENST00000414264.6
myoregulin
chr6_-_44313306 0.20 ENST00000244571.5
alanyl-tRNA synthetase 2, mitochondrial
chr6_+_54018992 0.20 ENST00000509997.5
muscular LMNA interacting protein
chr9_+_92964272 0.20 ENST00000468206.6
FYVE, RhoGEF and PH domain containing 3
chr13_+_77741160 0.20 ENST00000314070.9
ENST00000351546.7
SLAIN motif family member 1
chr6_+_13013513 0.20 ENST00000675203.1
phosphatase and actin regulator 1
chr15_-_78937198 0.20 ENST00000677207.1
cathepsin H
chr8_-_85341705 0.19 ENST00000517618.5
carbonic anhydrase 1
chr12_+_68809002 0.19 ENST00000539479.6
ENST00000393415.7
ENST00000523991.5
ENST00000543323.5
ENST00000393416.7
MDM2 proto-oncogene
chr6_+_26204552 0.19 ENST00000615164.2
H4 clustered histone 5
chr15_+_90717321 0.19 ENST00000355112.8
ENST00000681142.1
ENST00000648453.1
ENST00000560509.5
BLM RecQ like helicase
chr15_-_75712828 0.19 ENST00000308508.5
chondroitin sulfate proteoglycan 4
chr16_+_89093842 0.19 ENST00000317447.9
ENST00000614302.5
ENST00000537290.5
ENST00000540697.5
ENST00000406948.7
ENST00000378345.8
ENST00000541755.2
acyl-CoA synthetase family member 3
chr22_-_35840218 0.19 ENST00000414461.6
ENST00000416721.6
ENST00000449924.6
ENST00000262829.11
ENST00000397305.3
RNA binding fox-1 homolog 2
chr1_+_162069674 0.19 ENST00000361897.10
nitric oxide synthase 1 adaptor protein
chrX_+_23908006 0.19 ENST00000379211.8
ENST00000648352.1
chromosome X open reading frame 58
chr8_+_85107172 0.19 ENST00000360375.8
leucine rich repeat and coiled-coil centrosomal protein 1
chr19_+_22634317 0.19 ENST00000456783.3
zinc finger protein 492
chr12_-_11395556 0.18 ENST00000565533.1
ENST00000389362.6
ENST00000546254.3
proline rich protein BstNI subfamily 2
proline rich protein BstNI subfamily 1
chr7_-_112206380 0.18 ENST00000437633.6
ENST00000428084.6
dedicator of cytokinesis 4
chr6_+_158649997 0.18 ENST00000360448.8
ENST00000367081.7
ENST00000611299.5
synaptotagmin like 3
chr7_+_142111739 0.18 ENST00000550469.6
ENST00000477922.3
maltase-glucoamylase 2 (putative)
chr12_-_48999363 0.18 ENST00000421952.3
dendrin
chr6_+_26402289 0.18 ENST00000414912.2
butyrophilin subfamily 3 member A1
chr7_+_112206683 0.18 ENST00000361822.8
ENST00000421043.5
ENST00000425229.5
ENST00000450657.1
zinc finger protein 277
chr4_-_142305826 0.18 ENST00000514525.1
inositol polyphosphate-4-phosphatase type II B
chr2_+_165469647 0.18 ENST00000421875.5
ENST00000314499.11
ENST00000409664.5
ENST00000651982.1
cysteine and serine rich nuclear protein 3
chr4_-_69653223 0.18 ENST00000286604.8
ENST00000505512.1
ENST00000514019.1
UDP glucuronosyltransferase family 2 member A1 complex locus

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0048496 maintenance of organ identity(GO:0048496)
0.2 0.7 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.2 0.5 GO:0060279 positive regulation of ovulation(GO:0060279)
0.1 0.4 GO:1905026 positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903762) positive regulation of ventricular cardiac muscle cell action potential(GO:1903947) positive regulation of membrane repolarization during ventricular cardiac muscle cell action potential(GO:1905026) positive regulation of membrane repolarization during cardiac muscle cell action potential(GO:1905033)
0.1 1.0 GO:0035655 interleukin-18-mediated signaling pathway(GO:0035655)
0.1 0.6 GO:0051892 negative regulation of cardioblast differentiation(GO:0051892) regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.1 0.4 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.1 0.5 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.1 0.8 GO:0055129 L-proline biosynthetic process(GO:0055129)
0.1 0.5 GO:1902080 regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
0.1 1.3 GO:0070933 histone H4 deacetylation(GO:0070933)
0.1 1.5 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.1 0.4 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.1 0.4 GO:0030035 microspike assembly(GO:0030035)
0.1 0.6 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 0.7 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.1 0.9 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.1 0.2 GO:0035691 macrophage migration inhibitory factor signaling pathway(GO:0035691)
0.1 0.4 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.1 0.4 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.1 0.4 GO:0033274 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.1 0.8 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.1 0.2 GO:0072717 cellular response to actinomycin D(GO:0072717)
0.1 0.9 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.1 0.3 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.1 0.2 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
0.1 0.4 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.1 0.2 GO:1903288 positive regulation of potassium ion import(GO:1903288)
0.1 0.3 GO:2001180 negative regulation of interleukin-10 secretion(GO:2001180)
0.1 0.1 GO:0032954 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.1 0.2 GO:0033385 geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.0 0.2 GO:0060448 dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.0 0.3 GO:0035617 stress granule disassembly(GO:0035617)
0.0 0.2 GO:1990426 homologous recombination-dependent replication fork processing(GO:1990426)
0.0 0.1 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.0 0.2 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.3 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.0 0.2 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.0 0.1 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.0 0.1 GO:0097272 ammonia homeostasis(GO:0097272)
0.0 0.1 GO:0005988 lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989)
0.0 0.2 GO:1900147 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.0 0.8 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.4 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.2 GO:0046666 retinal cell programmed cell death(GO:0046666)
0.0 0.3 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.2 GO:1990523 bone regeneration(GO:1990523)
0.0 0.1 GO:0050992 dimethylallyl diphosphate biosynthetic process(GO:0050992) dimethylallyl diphosphate metabolic process(GO:0050993)
0.0 0.2 GO:0072757 cellular response to camptothecin(GO:0072757)
0.0 0.9 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.1 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.0 0.1 GO:0060133 somatotropin secreting cell development(GO:0060133)
0.0 0.1 GO:1902162 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) platelet alpha granule organization(GO:0070889) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.0 0.4 GO:0071492 cellular response to UV-A(GO:0071492)
0.0 0.3 GO:0072592 oxygen metabolic process(GO:0072592)
0.0 0.3 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.0 0.1 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.0 0.1 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.0 0.2 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.1 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.0 0.6 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.1 GO:0001983 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) baroreceptor response to increased systemic arterial blood pressure(GO:0001983)
0.0 0.3 GO:1904781 positive regulation of protein localization to centrosome(GO:1904781)
0.0 0.2 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.0 0.4 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.3 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.1 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982)
0.0 0.1 GO:0070945 neutrophil mediated killing of gram-negative bacterium(GO:0070945)
0.0 0.2 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.0 0.1 GO:0060018 astrocyte fate commitment(GO:0060018)
0.0 0.7 GO:0072643 interferon-gamma secretion(GO:0072643)
0.0 0.1 GO:0044376 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.0 0.1 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.2 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.1 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
0.0 0.1 GO:0038109 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
0.0 0.2 GO:0001957 intramembranous ossification(GO:0001957) regulation of mismatch repair(GO:0032423) direct ossification(GO:0036072)
0.0 0.4 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.1 GO:1904977 lymphatic endothelial cell migration(GO:1904977)
0.0 0.1 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.0 0.1 GO:0036233 glycine import(GO:0036233)
0.0 0.1 GO:1901162 primary amino compound biosynthetic process(GO:1901162)
0.0 1.1 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.1 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.0 0.1 GO:0048058 compound eye corneal lens development(GO:0048058)
0.0 0.1 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
0.0 0.1 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.0 0.1 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 0.1 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.0 0.1 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.0 0.1 GO:0010157 response to chlorate(GO:0010157)
0.0 0.3 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.1 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.0 0.2 GO:1904995 negative regulation of leukocyte tethering or rolling(GO:1903237) negative regulation of leukocyte adhesion to vascular endothelial cell(GO:1904995)
0.0 0.0 GO:0003162 atrioventricular node development(GO:0003162)
0.0 0.1 GO:0003219 cardiac right ventricle formation(GO:0003219) norepinephrine biosynthetic process(GO:0042421)
0.0 0.4 GO:0061365 positive regulation of triglyceride lipase activity(GO:0061365)
0.0 0.2 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.0 0.2 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.0 0.2 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.1 GO:0072023 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.0 0.1 GO:1904306 regulation of gastro-intestinal system smooth muscle contraction(GO:1904304) positive regulation of gastro-intestinal system smooth muscle contraction(GO:1904306)
0.0 0.1 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.0 0.2 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.0 0.1 GO:0006726 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.0 0.1 GO:0007341 penetration of zona pellucida(GO:0007341)
0.0 1.6 GO:0055008 cardiac muscle tissue morphogenesis(GO:0055008)
0.0 0.0 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.0 0.1 GO:0044565 dendritic cell proliferation(GO:0044565)
0.0 0.1 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.1 GO:0044375 regulation of peroxisome size(GO:0044375)
0.0 0.2 GO:0035524 proline transmembrane transport(GO:0035524)
0.0 0.1 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.0 0.6 GO:0002820 negative regulation of adaptive immune response(GO:0002820)
0.0 0.1 GO:0046116 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.0 0.3 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.0 0.4 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.1 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.1 GO:0046013 T cell homeostatic proliferation(GO:0001777) regulation of T cell homeostatic proliferation(GO:0046013)
0.0 0.1 GO:0021943 formation of radial glial scaffolds(GO:0021943)
0.0 0.3 GO:0008228 opsonization(GO:0008228)
0.0 1.9 GO:0071357 type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0 0.1 GO:0060336 negative regulation of response to interferon-gamma(GO:0060331) negative regulation of interferon-gamma-mediated signaling pathway(GO:0060336) cellular response to vitamin E(GO:0071306) negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.0 0.3 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.7 GO:0008089 anterograde axonal transport(GO:0008089)
0.0 0.0 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.0 0.1 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.3 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.1 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.0 0.0 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.0 0.1 GO:0032264 IMP salvage(GO:0032264)
0.0 0.1 GO:0034214 protein hexamerization(GO:0034214)
0.0 0.1 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.1 GO:0070269 pyroptosis(GO:0070269)
0.0 0.4 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.4 GO:0042481 regulation of odontogenesis(GO:0042481)
0.0 0.1 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.0 0.0 GO:0030916 otic vesicle formation(GO:0030916)
0.0 0.2 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 0.1 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.4 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.4 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.0 0.1 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.1 GO:0060988 lipid tube assembly(GO:0060988)
0.0 0.0 GO:0003363 lamellipodium assembly involved in ameboidal cell migration(GO:0003363)
0.0 0.2 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.6 GO:0048286 lung alveolus development(GO:0048286)
0.0 1.8 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.6 GO:0030318 melanocyte differentiation(GO:0030318)
0.0 0.2 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.0 0.5 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.0 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.0 1.2 GO:0051965 positive regulation of synapse assembly(GO:0051965)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0097543 ciliary inversin compartment(GO:0097543)
0.2 0.5 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.1 0.4 GO:0005960 glycine cleavage complex(GO:0005960)
0.1 0.4 GO:0097362 MCM8-MCM9 complex(GO:0097362)
0.1 0.2 GO:0001674 female germ cell nucleus(GO:0001674)
0.1 0.2 GO:0033593 BRCA2-MAGE-D1 complex(GO:0033593)
0.1 0.4 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.1 0.4 GO:0005726 perichromatin fibrils(GO:0005726)
0.1 0.8 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.1 0.2 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.0 0.2 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0 0.1 GO:0044609 DBIRD complex(GO:0044609)
0.0 0.1 GO:1905103 integral component of lysosomal membrane(GO:1905103)
0.0 0.2 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.0 0.4 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.3 GO:0032437 cuticular plate(GO:0032437)
0.0 0.1 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.0 0.3 GO:0030891 VCB complex(GO:0030891)
0.0 0.3 GO:0070081 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.1 GO:0033186 CAF-1 complex(GO:0033186)
0.0 0.4 GO:0016013 syntrophin complex(GO:0016013)
0.0 1.1 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.7 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.6 GO:0016580 Sin3 complex(GO:0016580)
0.0 1.2 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.4 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.3 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.2 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 1.6 GO:0031941 filamentous actin(GO:0031941)
0.0 0.1 GO:0060987 lipid tube(GO:0060987)
0.0 0.1 GO:0031673 H zone(GO:0031673)
0.0 0.3 GO:0030478 actin cap(GO:0030478)
0.0 0.1 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753) proton-transporting ATP synthase complex(GO:0045259)
0.0 0.5 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.2 GO:0097208 alveolar lamellar body(GO:0097208)
0.0 0.1 GO:0071821 FANCM-MHF complex(GO:0071821)
0.0 0.0 GO:0044611 nuclear pore inner ring(GO:0044611)
0.0 0.1 GO:0016589 NURF complex(GO:0016589)
0.0 0.3 GO:0005861 troponin complex(GO:0005861)
0.0 0.3 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.1 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.1 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.1 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.0 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.0 0.1 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.2 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.1 GO:0044294 dendritic growth cone(GO:0044294)
0.0 1.9 GO:0032587 ruffle membrane(GO:0032587)
0.0 1.7 GO:0005814 centriole(GO:0005814)
0.0 0.1 GO:0031010 ISWI-type complex(GO:0031010)
0.0 0.7 GO:1904115 axon cytoplasm(GO:1904115)
0.0 0.1 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0042008 interleukin-18 receptor activity(GO:0042008)
0.1 0.8 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.1 0.3 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.1 0.5 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 0.9 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.1 0.6 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.5 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.4 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.1 0.3 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.1 0.3 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.1 0.1 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 0.2 GO:0004339 glucan 1,4-alpha-glucosidase activity(GO:0004339)
0.1 0.4 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.1 0.6 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.1 0.9 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 1.2 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.2 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 0.4 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.3 GO:0004127 cytidylate kinase activity(GO:0004127)
0.0 0.3 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.0 0.4 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.4 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 0.2 GO:0004471 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.0 0.1 GO:0004452 isopentenyl-diphosphate delta-isomerase activity(GO:0004452)
0.0 0.9 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.2 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.0 0.1 GO:0050146 nucleoside phosphotransferase activity(GO:0050146)
0.0 2.3 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 0.1 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.0 0.2 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.0 0.1 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.2 GO:0009378 four-way junction helicase activity(GO:0009378)
0.0 0.1 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.2 GO:0034235 GPI anchor binding(GO:0034235)
0.0 0.9 GO:0005549 odorant binding(GO:0005549)
0.0 0.1 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.7 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.2 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.0 1.1 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.1 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 0.1 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.0 0.2 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.1 GO:0031716 calcitonin receptor binding(GO:0031716)
0.0 0.2 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.2 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.4 GO:0016594 glycine binding(GO:0016594)
0.0 0.2 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 0.1 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 0.1 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.3 GO:0031014 troponin T binding(GO:0031014)
0.0 0.2 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.1 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.1 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.4 GO:0051400 BH domain binding(GO:0051400)
0.0 0.1 GO:0004771 sterol esterase activity(GO:0004771)
0.0 0.1 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
0.0 0.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.3 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.1 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.0 0.2 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.0 GO:0016608 growth hormone-releasing hormone activity(GO:0016608)
0.0 1.1 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.2 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.0 0.1 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.1 GO:0005119 smoothened binding(GO:0005119) hedgehog family protein binding(GO:0097108)
0.0 0.4 GO:0017166 vinculin binding(GO:0017166)
0.0 0.2 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.8 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.4 GO:0008242 omega peptidase activity(GO:0008242)
0.0 0.8 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.4 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 1.7 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.3 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.1 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.3 GO:0038187 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 0.1 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.0 GO:0004750 ribulose-phosphate 3-epimerase activity(GO:0004750)
0.0 0.3 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.0 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.0 0.1 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.0 0.2 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.1 GO:0042301 phosphate ion binding(GO:0042301)
0.0 0.1 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.1 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.0 0.1 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.3 GO:0005521 lamin binding(GO:0005521)
0.0 0.0 GO:0001596 angiotensin type I receptor activity(GO:0001596) bradykinin receptor binding(GO:0031711)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.4 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.5 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 1.3 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 1.0 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.4 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.5 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.8 PID AURORA B PATHWAY Aurora B signaling
0.0 0.3 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 1.2 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.6 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.8 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.9 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 1.1 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 1.6 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.2 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.4 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.4 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.3 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.8 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.1 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 2.1 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.4 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.4 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.5 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.1 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.3 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.3 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.5 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction