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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for SOX17

Z-value: 0.70

Motif logo

Transcription factors associated with SOX17

Gene Symbol Gene ID Gene Info
ENSG00000164736.6 SOX17

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX17hg38_v1_chr8_+_54457927_544579430.222.8e-01Click!

Activity profile of SOX17 motif

Sorted Z-values of SOX17 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX17

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr17_+_43006740 3.15 ENST00000438323.2
ENST00000415816.7
interferon induced protein 35
chr11_-_102798148 1.67 ENST00000315274.7
matrix metallopeptidase 1
chr4_-_73998669 1.44 ENST00000296027.5
C-X-C motif chemokine ligand 5
chr20_-_63568074 1.38 ENST00000427522.6
helicase with zinc finger 2
chr10_-_48605032 1.32 ENST00000249601.9
Rho GTPase activating protein 22
chr2_-_224947030 1.25 ENST00000409592.7
dedicator of cytokinesis 10
chr14_+_94110728 1.16 ENST00000616764.4
ENST00000618863.1
ENST00000611954.4
ENST00000618200.4
ENST00000621160.4
ENST00000555819.5
ENST00000620396.4
ENST00000612813.4
ENST00000620066.1
interferon alpha inducible protein 27
chr3_-_122564232 1.00 ENST00000471785.5
ENST00000466126.1
poly(ADP-ribose) polymerase family member 9
chr5_-_147453888 0.95 ENST00000398514.7
dihydropyrimidinase like 3
chr1_+_205256189 0.87 ENST00000329800.7
transmembrane and coiled-coil domain family 2
chr17_+_42980547 0.86 ENST00000361677.5
ENST00000589705.1
RUN domain containing 1
chr1_+_86547070 0.85 ENST00000370563.3
chloride channel accessory 4
chr11_-_7674206 0.82 ENST00000533558.5
ENST00000527542.5
cytochrome b5 reductase 2
chr7_-_115968302 0.81 ENST00000457268.5
transcription factor EC
chr3_-_122564253 0.78 ENST00000492382.5
ENST00000682323.1
ENST00000462315.5
poly(ADP-ribose) polymerase family member 9
chr8_+_12104389 0.77 ENST00000400085.7
zinc finger protein 705D
chr12_-_110920568 0.72 ENST00000548438.1
ENST00000228841.15
myosin light chain 2
chr18_+_34709356 0.71 ENST00000585446.1
ENST00000681241.1
dystrobrevin alpha
chr3_+_122564327 0.70 ENST00000296161.9
ENST00000383661.3
deltex E3 ubiquitin ligase 3L
chrX_-_8171267 0.70 ENST00000317103.5
variable charge X-linked 2
chr9_+_96928310 0.67 ENST00000354649.7
NUT family member 2G
chr1_+_172452885 0.66 ENST00000367725.4
chromosome 1 open reading frame 105
chrX_+_49341192 0.65 ENST00000621907.1
G antigen 2E
chr14_+_21057822 0.63 ENST00000308227.2
ribonuclease A family member 8
chr2_+_102418642 0.63 ENST00000264260.6
interleukin 18 receptor accessory protein
chr2_+_102311502 0.57 ENST00000404917.6
ENST00000410040.5
interleukin 1 receptor like 1
interleukin 18 receptor 1
chr1_+_53894181 0.54 ENST00000361921.8
ENST00000322679.10
ENST00000613679.4
ENST00000617230.2
ENST00000610607.4
ENST00000532493.5
ENST00000525202.5
ENST00000524406.5
ENST00000388876.3
iodothyronine deiodinase 1
chr3_+_46370854 0.54 ENST00000292303.4
C-C motif chemokine receptor 5
chr11_-_6030758 0.53 ENST00000641900.1
olfactory receptor family 56 subfamily A member 1
chr1_-_120054225 0.53 ENST00000602566.6
notch receptor 2
chr1_-_205121986 0.52 ENST00000367164.1
RB binding protein 5, histone lysine methyltransferase complex subunit
chr19_+_16661121 0.51 ENST00000187762.7
ENST00000599479.1
transmembrane protein 38A
chr1_-_205121964 0.50 ENST00000264515.11
RB binding protein 5, histone lysine methyltransferase complex subunit
chr6_+_158649997 0.47 ENST00000360448.8
ENST00000367081.7
ENST00000611299.5
synaptotagmin like 3
chr1_+_15617415 0.45 ENST00000480945.6
DNA damage inducible 1 homolog 2
chr8_+_109086585 0.45 ENST00000518632.2
thyrotropin releasing hormone receptor
chr4_-_121164314 0.42 ENST00000057513.8
TNFAIP3 interacting protein 3
chr22_-_24555920 0.41 ENST00000621833.4
ENST00000404664.7
guanylyl cyclase domain containing 1
chr9_-_127778659 0.41 ENST00000314830.13
SH2 domain containing 3C
chr9_+_69123009 0.41 ENST00000647986.1
tight junction protein 2
chr16_+_33827140 0.40 ENST00000562905.2
immunoglobulin heavy variable 3/OR16-13 (non-functional)
chr6_-_31357171 0.40 ENST00000412585.7
ENST00000434333.1
major histocompatibility complex, class I, B
chr15_-_89211803 0.39 ENST00000563254.1
retinaldehyde binding protein 1
chr22_-_24555086 0.38 ENST00000447813.6
ENST00000402766.5
ENST00000435822.6
ENST00000407471.7
guanylyl cyclase domain containing 1
chr4_+_70028452 0.38 ENST00000530128.5
ENST00000381057.3
ENST00000673563.1
histatin 3
chr11_-_35418966 0.38 ENST00000531628.2
solute carrier family 1 member 2
chr6_+_31948956 0.37 ENST00000483004.1
complement factor B
chr1_+_13254212 0.37 ENST00000622421.2
PRAME family member 5
chr17_-_57745292 0.37 ENST00000299415.3
coiled-coil domain containing 182
chr17_-_75855204 0.36 ENST00000589642.5
ENST00000593002.1
ENST00000590221.5
ENST00000587374.5
ENST00000585462.5
ENST00000254806.8
ENST00000433525.6
ENST00000626827.2
WW domain binding protein 2
chrY_-_23694579 0.36 ENST00000343584.10
PTPN13 like Y-linked pseudogene 3
chr3_+_111542178 0.36 ENST00000283285.10
ENST00000352690.9
CD96 molecule
chr15_-_33067884 0.35 ENST00000334528.13
formin 1
chr19_+_32345593 0.35 ENST00000311921.8
ENST00000355898.6
ENST00000544431.5
zinc finger protein 507
chr1_-_6602885 0.35 ENST00000377663.3
kelch like family member 21
chr1_+_107139996 0.34 ENST00000370073.6
ENST00000370074.8
netrin G1
chr1_+_84408230 0.34 ENST00000370662.3
deoxyribonuclease 2 beta
chr6_+_82363199 0.34 ENST00000535040.4
trophoblast glycoprotein
chr14_-_106557465 0.33 ENST00000390625.3
immunoglobulin heavy variable 3-49
chr19_+_10654261 0.32 ENST00000449870.5
interleukin enhancer binding factor 3
chr1_+_10430070 0.32 ENST00000400900.6
CENPS-CORT readthrough
chr1_-_150808251 0.31 ENST00000271651.8
ENST00000676970.1
ENST00000679260.1
ENST00000676751.1
ENST00000677887.1
cathepsin K
chr2_+_232662733 0.31 ENST00000410095.5
ENST00000611312.1
EF-hand domain family member D1
chr3_-_48440022 0.31 ENST00000447018.5
ENST00000442740.1
ENST00000412398.6
ENST00000395694.7
coiled-coil domain containing 51
chr5_-_97183203 0.31 ENST00000508447.1
ENST00000283109.8
RIO kinase 2
chr1_-_205775182 0.31 ENST00000446390.6
RAB29, member RAS oncogene family
chr12_-_49897056 0.30 ENST00000552863.5
Fas apoptotic inhibitory molecule 2
chr17_-_4949037 0.30 ENST00000572383.1
profilin 1
chr5_+_168486462 0.30 ENST00000231572.8
ENST00000626454.1
arginyl-tRNA synthetase 1
chr18_+_34710249 0.29 ENST00000680346.1
ENST00000348997.9
ENST00000681274.1
ENST00000680822.1
ENST00000680767.2
ENST00000597599.5
ENST00000444659.6
dystrobrevin alpha
chr2_-_70995336 0.29 ENST00000606025.5
novel protein
chr3_-_98035295 0.28 ENST00000621172.4
gamma-aminobutyric acid type A receptor subunit rho3
chr1_+_46671871 0.28 ENST00000564373.1
testis expressed 38
chr7_-_24757926 0.28 ENST00000342947.9
ENST00000419307.6
gasdermin E
chr11_-_102625332 0.28 ENST00000260228.3
matrix metallopeptidase 20
chr11_+_60396435 0.28 ENST00000395005.6
membrane spanning 4-domains A14
chr17_-_31901658 0.28 ENST00000261708.9
UTP6 small subunit processome component
chr3_+_121567924 0.27 ENST00000334384.5
arginine-fifty homeobox
chr19_+_2163915 0.27 ENST00000398665.8
DOT1 like histone lysine methyltransferase
chr22_+_44069043 0.27 ENST00000404989.1
parvin beta
chr17_-_2266131 0.27 ENST00000570606.5
ENST00000354901.8
SMG6 nonsense mediated mRNA decay factor
chr4_-_99144238 0.26 ENST00000512499.5
ENST00000504125.1
ENST00000505590.5
ENST00000629236.2
ENST00000508393.5
ENST00000265512.12
alcohol dehydrogenase 4 (class II), pi polypeptide
chr4_+_94207845 0.26 ENST00000457823.6
ENST00000354268.9
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr6_-_42142604 0.26 ENST00000356542.5
ENST00000341865.9
chromosome 6 open reading frame 132
chr12_+_26011713 0.26 ENST00000542004.5
Ras association domain family member 8
chr6_-_118935146 0.26 ENST00000619706.5
ENST00000316316.10
minichromosome maintenance 9 homologous recombination repair factor
chr19_+_34404379 0.26 ENST00000246535.4
programmed cell death 2 like
chr11_+_71538025 0.26 ENST00000398534.4
keratin associated protein 5-8
chrX_-_152709260 0.25 ENST00000535353.3
ENST00000638741.1
ENST00000640702.1
CSAG family member 2
chr2_-_54987578 0.25 ENST00000486085.5
reticulon 4
chr12_+_21527017 0.25 ENST00000535033.5
spexin hormone
chr3_+_98168700 0.25 ENST00000383696.4
olfactory receptor family 5 subfamily H member 15
chr6_-_42722590 0.25 ENST00000230381.7
peripherin 2
chr20_+_37777262 0.25 ENST00000373469.1
catenin beta like 1
chr19_+_49453211 0.25 ENST00000540132.5
ENST00000293350.9
ENST00000455361.6
aldehyde dehydrogenase 16 family member A1
chr19_-_3626746 0.25 ENST00000429344.7
ENST00000248420.9
ENST00000221899.7
cactin, spliceosome C complex subunit
chr3_-_139476508 0.25 ENST00000232217.6
retinol binding protein 2
chr1_+_46671821 0.25 ENST00000334122.5
ENST00000415500.1
testis expressed 38
chr1_-_145995713 0.25 ENST00000425134.2
thioredoxin interacting protein
chr18_+_9885726 0.25 ENST00000611534.1
ENST00000536353.2
ENST00000584255.1
thioredoxin domain containing 2
chr2_-_151971750 0.24 ENST00000636598.1
calcium voltage-gated channel auxiliary subunit beta 4
chr18_+_58221535 0.24 ENST00000431212.6
ENST00000586268.5
ENST00000587190.5
NEDD4 like E3 ubiquitin protein ligase
chr17_-_3063607 0.24 ENST00000575751.1
olfactory receptor family 1 subfamily D member 5
chr2_+_71130586 0.24 ENST00000498451.2
ENST00000244230.7
M-phase phosphoprotein 10
chr17_-_41489907 0.23 ENST00000328119.11
keratin 36
chr11_-_35419098 0.23 ENST00000606205.6
ENST00000645303.1
solute carrier family 1 member 2
chr1_+_40374648 0.23 ENST00000372708.5
small ArfGAP2
chr3_+_185586270 0.23 ENST00000296257.10
SUMO specific peptidase 2
chr1_+_47333863 0.23 ENST00000471289.2
ENST00000450808.2
cytidine/uridine monophosphate kinase 1
chr6_+_29301701 0.23 ENST00000641895.1
olfactory receptor family 14 subfamily J member 1
chr1_-_6602859 0.23 ENST00000377658.8
kelch like family member 21
chr6_-_118710065 0.22 ENST00000392500.7
ENST00000368488.9
ENST00000434604.5
centrosomal protein 85 like
chr22_-_17773976 0.22 ENST00000317361.11
BH3 interacting domain death agonist
chr6_+_125956696 0.22 ENST00000229633.7
histidine triad nucleotide binding protein 3
chr1_+_47333774 0.22 ENST00000371873.10
cytidine/uridine monophosphate kinase 1
chr2_-_89117844 0.22 ENST00000490686.1
immunoglobulin kappa variable 1-17
chrX_-_13319952 0.22 ENST00000622204.1
ENST00000380622.5
ataxin 3 like
chr6_-_52803807 0.22 ENST00000334575.6
glutathione S-transferase alpha 1
chr1_-_13155961 0.22 ENST00000624207.1
PRAME family member 26
chr6_+_135851681 0.22 ENST00000308191.11
phosphodiesterase 7B
chr6_+_125153649 0.22 ENST00000304877.17
ENST00000368402.9
ENST00000368388.6
ENST00000534000.6
TPD52 like 1
chr22_-_32255344 0.22 ENST00000266086.6
solute carrier family 5 member 4
chr8_+_109087424 0.21 ENST00000311762.2
thyrotropin releasing hormone receptor
chr16_-_30012294 0.21 ENST00000564979.5
ENST00000563378.5
double C2 domain alpha
chr15_-_76012390 0.21 ENST00000394907.8
neuregulin 4
chr1_-_12945416 0.21 ENST00000415464.6
PRAME family member 6
chr21_-_32603237 0.21 ENST00000431599.1
cilia and flagella associated protein 298
chr1_-_120176450 0.20 ENST00000578049.4
SEC22 homolog B, vesicle trafficking protein
chr1_-_12886201 0.20 ENST00000235349.6
PRAME family member 4
chr7_+_76424922 0.20 ENST00000394857.8
zona pellucida glycoprotein 3
chr19_-_49453472 0.20 ENST00000601825.1
ENST00000596049.5
ENST00000599366.5
ENST00000597415.5
PIH1 domain containing 1
chrX_+_8464830 0.20 ENST00000453306.4
ENST00000381032.6
ENST00000444481.3
variable charge X-linked 3B
chr6_+_31571957 0.20 ENST00000454783.5
lymphotoxin alpha
chr17_+_70104848 0.20 ENST00000392670.5
potassium inwardly rectifying channel subfamily J member 16
chrX_-_104013708 0.20 ENST00000217926.7
H2B.W histone 1
chr11_+_5351508 0.20 ENST00000380219.1
olfactory receptor family 51 subfamily B member 6
chr16_+_24846231 0.20 ENST00000568579.5
ENST00000567758.5
ENST00000569071.1
solute carrier family 5 member 11
chr7_+_135557904 0.19 ENST00000285968.11
nucleoporin 205
chr11_-_123885627 0.19 ENST00000528595.1
ENST00000375026.7
transmembrane protein 225
chr1_+_13060769 0.19 ENST00000617807.3
heterogeneous nuclear ribonucleoprotein C like 3
chr2_+_86441341 0.19 ENST00000312912.10
ENST00000409064.5
lysine demethylase 3A
chrX_-_6535118 0.19 ENST00000381089.7
ENST00000612369.4
ENST00000398729.1
variable charge X-linked 3A
chr1_+_13315581 0.19 ENST00000376152.2
PRAME family member 15
chr7_-_29146436 0.19 ENST00000396276.7
carboxypeptidase vitellogenic like
chr9_-_136866265 0.19 ENST00000371648.4
ENST00000371649.5
endothelial differentiation related factor 1
chr6_-_125301900 0.18 ENST00000608295.5
ENST00000398153.7
ENST00000608284.1
HD domain containing 2
chr19_+_41376499 0.18 ENST00000392002.7
transmembrane protein 91
chr19_-_12919256 0.18 ENST00000293695.8
synaptonemal complex central element protein 2
chr11_+_55885920 0.18 ENST00000244891.3
tripartite motif-containing 51
chr1_+_14929734 0.18 ENST00000376028.8
ENST00000400798.6
kazrin, periplakin interacting protein
chr17_-_75289212 0.18 ENST00000582778.1
ENST00000581988.5
ENST00000579207.5
ENST00000583332.5
ENST00000442286.6
ENST00000580151.5
ENST00000580994.5
ENST00000584438.1
ENST00000416858.7
ENST00000320362.7
solute carrier family 25 member 19
chr12_-_8662619 0.18 ENST00000544889.1
ENST00000543369.5
microfibril associated protein 5
chr7_-_29146527 0.18 ENST00000265394.10
carboxypeptidase vitellogenic like
chr8_-_33599935 0.18 ENST00000523956.1
ENST00000256261.9
dual specificity phosphatase 26
chr8_+_117134989 0.17 ENST00000456015.7
solute carrier family 30 member 8
chr1_+_207496268 0.17 ENST00000529814.1
complement C3b/C4b receptor 1 (Knops blood group)
chr1_+_59310071 0.17 ENST00000371212.5
FGGY carbohydrate kinase domain containing
chr2_+_27628996 0.17 ENST00000616939.4
ENST00000264718.7
ENST00000610189.2
GPN-loop GTPase 1
chr11_+_60378524 0.17 ENST00000530614.5
ENST00000530027.5
ENST00000300184.8
ENST00000530234.2
ENST00000528215.1
ENST00000531787.5
membrane spanning 4-domains A7
membrane spanning 4-domains A14
chr3_-_45796518 0.17 ENST00000413781.1
ENST00000358525.9
solute carrier family 6 member 20
chr12_-_76068933 0.17 ENST00000552056.5
nucleosome assembly protein 1 like 1
chr11_+_89924064 0.16 ENST00000623787.3
tripartite motif containing 49D2
chr1_+_174875505 0.16 ENST00000486220.5
RAB GTPase activating protein 1 like
chr6_-_132659178 0.16 ENST00000275216.3
trace amine associated receptor 1
chr19_-_53254841 0.16 ENST00000601828.5
ENST00000599012.5
ENST00000598513.6
ENST00000598806.5
zinc finger protein 677
chr12_-_118359639 0.16 ENST00000541786.5
ENST00000419821.6
ENST00000541878.5
TAO kinase 3
chr8_+_94641199 0.16 ENST00000646773.1
ENST00000454170.7
epithelial splicing regulatory protein 1
chr11_+_60378475 0.16 ENST00000358246.5
membrane spanning 4-domains A7
chr11_-_89922245 0.16 ENST00000420869.3
tripartite motif containing 49D1
chr3_+_151733919 0.16 ENST00000356517.4
arylacetamide deacetylase like 2
chr12_+_25052732 0.16 ENST00000547044.5
inositol 1,4,5-triphosphate receptor associated 2
chr12_+_64824602 0.16 ENST00000539867.6
ENST00000544457.1
ENST00000539120.1
TBC1 domain family member 30
chr10_-_113854368 0.16 ENST00000369305.1
DNA cross-link repair 1A
chr7_+_99408609 0.16 ENST00000403633.6
BUD31 homolog
chr7_-_122304738 0.16 ENST00000442488.7
FEZ family zinc finger 1
chr10_-_49269 0.15 ENST00000562809.1
ENST00000568866.5
ENST00000561967.1
ENST00000568584.6
tubulin beta 8 class VIII
chr1_-_160523204 0.15 ENST00000368055.1
ENST00000368057.8
ENST00000368059.7
SLAM family member 6
chr12_-_11310420 0.15 ENST00000621732.4
ENST00000445719.2
ENST00000279575.7
proline rich protein BstNI subfamily 4
chr19_+_10654327 0.15 ENST00000407004.7
ENST00000589998.5
ENST00000589600.5
interleukin enhancer binding factor 3
chr1_+_13061158 0.15 ENST00000681473.1
heterogeneous nuclear ribonucleoprotein C like 3
chr1_-_13165631 0.15 ENST00000323770.8
heterogeneous nuclear ribonucleoprotein C like 4
chr7_+_148339452 0.15 ENST00000463592.3
contactin associated protein 2
chr17_-_41168219 0.14 ENST00000391356.4
keratin associated protein 4-3
chr19_-_45406327 0.14 ENST00000593226.5
ENST00000418234.6
protein phosphatase 1 regulatory subunit 13 like
chr6_+_31572279 0.14 ENST00000418386.3
lymphotoxin alpha
chr3_+_178419123 0.14 ENST00000614557.1
ENST00000455307.5
ENST00000436432.1
potassium large conductance calcium-activated channel, subfamily M, beta member 2 (KCNMB2-IT1 - KCNMB2 readthrough transcript)
long intergenic non-protein coding RNA 1014
chr7_+_95485934 0.14 ENST00000325885.6
ankyrin repeat and SOCS box containing 4
chrX_+_49331616 0.14 ENST00000612958.1
G antigen 13
chr17_-_66229380 0.14 ENST00000205948.11
apolipoprotein H
chr4_-_149815826 0.14 ENST00000636793.2
ENST00000636414.1
IQ motif containing M
chrX_+_120604084 0.14 ENST00000371317.10
MCTS1 re-initiation and release factor
chr9_-_128275935 0.14 ENST00000610329.4
golgin A2
chr2_-_100322495 0.14 ENST00000393437.8
LON peptidase N-terminal domain and ring finger 2
chr14_-_106088573 0.14 ENST00000632099.1
immunoglobulin heavy variable 3-64D
chr1_+_13070853 0.13 ENST00000619661.2
PRAME family member 25
chr12_-_11031407 0.13 ENST00000390675.2
taste 2 receptor member 31
chr1_+_171248471 0.13 ENST00000402921.6
ENST00000617670.6
ENST00000367750.7
flavin containing dimethylaniline monoxygenase 1
chr12_-_8662703 0.13 ENST00000535336.5
microfibril associated protein 5
chr3_+_125969214 0.13 ENST00000508088.1
rhophilin associated tail protein 1B
chr3_-_45796467 0.13 ENST00000353278.8
ENST00000456124.6
solute carrier family 6 member 20

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.8 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.2 0.5 GO:0002728 negative regulation of natural killer cell cytokine production(GO:0002728)
0.1 0.6 GO:0061760 antifungal innate immune response(GO:0061760)
0.1 0.3 GO:0002876 positive regulation of chronic inflammatory response to antigenic stimulus(GO:0002876)
0.1 1.8 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 0.3 GO:0034729 histone H3-K79 methylation(GO:0034729)
0.1 0.6 GO:0035655 interleukin-18-mediated signaling pathway(GO:0035655)
0.1 0.4 GO:0072092 ureteric bud invasion(GO:0072092)
0.1 0.2 GO:1903939 negative regulation of histone H3-K9 dimethylation(GO:1900110) regulation of TORC2 signaling(GO:1903939)
0.1 0.2 GO:0046292 formaldehyde metabolic process(GO:0046292)
0.1 0.4 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.1 0.2 GO:0030974 thiamine pyrophosphate transport(GO:0030974)
0.1 0.7 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.1 0.2 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.1 0.2 GO:1990022 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.1 0.2 GO:0045957 regulation of complement activation, alternative pathway(GO:0030451) negative regulation of complement activation, alternative pathway(GO:0045957)
0.1 0.5 GO:0019856 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.1 0.5 GO:0039663 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.1 0.2 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.1 0.3 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.1 0.3 GO:0034334 adherens junction maintenance(GO:0034334)
0.1 0.2 GO:2000196 positive regulation of female gonad development(GO:2000196) negative regulation of binding of sperm to zona pellucida(GO:2000360)
0.0 0.5 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.1 GO:0036451 cap mRNA methylation(GO:0036451)
0.0 1.4 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.0 0.6 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.1 GO:1903238 positive regulation of leukocyte tethering or rolling(GO:1903238)
0.0 0.4 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.0 0.3 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.1 GO:0030573 bile acid catabolic process(GO:0030573)
0.0 1.9 GO:0032461 positive regulation of protein oligomerization(GO:0032461)
0.0 0.1 GO:0071676 negative regulation of mononuclear cell migration(GO:0071676)
0.0 0.4 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.0 0.1 GO:0002325 natural killer cell differentiation involved in immune response(GO:0002325) negative regulation of natural killer cell differentiation(GO:0032824) regulation of natural killer cell differentiation involved in immune response(GO:0032826) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827)
0.0 0.1 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.0 0.1 GO:0036245 cellular response to menadione(GO:0036245)
0.0 0.6 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.1 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.3 GO:1904304 regulation of gastro-intestinal system smooth muscle contraction(GO:1904304) positive regulation of gastro-intestinal system smooth muscle contraction(GO:1904306)
0.0 4.6 GO:0071357 type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0 0.2 GO:0007056 spindle assembly involved in female meiosis(GO:0007056)
0.0 0.1 GO:0002769 natural killer cell inhibitory signaling pathway(GO:0002769)
0.0 0.1 GO:0071109 superior temporal gyrus development(GO:0071109)
0.0 0.1 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.0 0.2 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.2 GO:0015798 myo-inositol transport(GO:0015798)
0.0 0.2 GO:0021678 third ventricle development(GO:0021678)
0.0 0.8 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.3 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.0 0.3 GO:1904354 negative regulation of telomere capping(GO:1904354)
0.0 0.1 GO:0006532 aspartate biosynthetic process(GO:0006532)
0.0 0.1 GO:0031064 negative regulation of histone deacetylation(GO:0031064)
0.0 0.1 GO:0070103 regulation of interleukin-6-mediated signaling pathway(GO:0070103) positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.0 0.1 GO:0032848 negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
0.0 0.5 GO:0006590 thyroid hormone generation(GO:0006590)
0.0 0.1 GO:0090306 spindle assembly involved in meiosis(GO:0090306)
0.0 0.1 GO:0035627 ceramide transport(GO:0035627)
0.0 0.3 GO:0015824 proline transport(GO:0015824)
0.0 0.3 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.4 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.2 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.3 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.2 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.3 GO:0070166 enamel mineralization(GO:0070166)
0.0 0.2 GO:2000825 positive regulation of androgen receptor activity(GO:2000825)
0.0 0.1 GO:0018874 benzoate metabolic process(GO:0018874)
0.0 0.3 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 0.2 GO:0006662 glycerol ether metabolic process(GO:0006662)
0.0 1.0 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.3 GO:1903441 protein localization to ciliary membrane(GO:1903441)
0.0 0.3 GO:0006069 ethanol oxidation(GO:0006069)
0.0 0.1 GO:0061709 reticulophagy(GO:0061709)
0.0 0.2 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.0 0.2 GO:0043697 forebrain anterior/posterior pattern specification(GO:0021797) dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.0 1.1 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.1 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.6 GO:0010390 histone monoubiquitination(GO:0010390)
0.0 0.1 GO:0010903 negative regulation of very-low-density lipoprotein particle remodeling(GO:0010903)
0.0 0.1 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.0 0.3 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.2 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.1 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.1 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.0 0.2 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.9 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.0 0.1 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.1 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.0 0.2 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.6 GO:0034629 cellular protein complex localization(GO:0034629)
0.0 0.1 GO:0098704 fructose transport(GO:0015755) fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.0 0.1 GO:0045007 depurination(GO:0045007)
0.0 0.2 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.0 0.8 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.2 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.0 0.1 GO:0036438 maintenance of lens transparency(GO:0036438)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.1 0.7 GO:0005827 polar microtubule(GO:0005827)
0.1 1.0 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 0.3 GO:0020003 symbiont-containing vacuole(GO:0020003)
0.1 0.2 GO:0044611 nuclear pore inner ring(GO:0044611)
0.1 0.3 GO:0097362 MCM8-MCM9 complex(GO:0097362)
0.1 0.2 GO:0034457 Mpp10 complex(GO:0034457)
0.0 0.3 GO:0036021 endolysosome lumen(GO:0036021)
0.0 0.7 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.3 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.4 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.2 GO:0002081 outer acrosomal membrane(GO:0002081)
0.0 0.1 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.0 0.3 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.3 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.2 GO:0000801 central element(GO:0000801)
0.0 0.2 GO:0070761 pre-snoRNP complex(GO:0070761)
0.0 0.1 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.0 0.2 GO:0001520 outer dense fiber(GO:0001520)
0.0 0.2 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.7 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.8 GO:0030673 axolemma(GO:0030673)
0.0 0.1 GO:0097209 epidermal lamellar body(GO:0097209)
0.0 0.8 GO:0031941 filamentous actin(GO:0031941)
0.0 0.1 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.3 GO:0000974 Prp19 complex(GO:0000974)
0.0 1.2 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.1 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.3 GO:0031045 dense core granule(GO:0031045)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0042008 interleukin-18 receptor activity(GO:0042008)
0.1 0.3 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.1 0.5 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.1 0.6 GO:0004522 ribonuclease A activity(GO:0004522)
0.1 1.4 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 0.5 GO:0009041 uridylate kinase activity(GO:0009041)
0.1 1.0 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.1 0.4 GO:0005502 11-cis retinal binding(GO:0005502)
0.1 0.8 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.1 1.8 GO:0070403 NAD+ binding(GO:0070403)
0.1 0.2 GO:0090422 thiamine pyrophosphate transporter activity(GO:0090422)
0.1 0.5 GO:0038049 transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049)
0.1 0.2 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.1 0.2 GO:0019150 D-ribulokinase activity(GO:0019150)
0.1 0.2 GO:0004877 complement component C4b receptor activity(GO:0001861) complement component C3b receptor activity(GO:0004877)
0.1 0.4 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.1 0.3 GO:0035276 ethanol binding(GO:0035276)
0.0 1.0 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.6 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.1 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.0 0.4 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.1 GO:0047787 delta4-3-oxosteroid 5beta-reductase activity(GO:0047787)
0.0 0.5 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 1.2 GO:0005521 lamin binding(GO:0005521)
0.0 0.5 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.2 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.0 0.7 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.1 GO:0031208 POZ domain binding(GO:0031208)
0.0 0.2 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0 0.8 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.1 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.0 0.2 GO:0034191 apolipoprotein A-I receptor binding(GO:0034191)
0.0 0.1 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.0 0.1 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.0 0.1 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.0 0.2 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.1 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.2 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.1 GO:0016503 pheromone receptor activity(GO:0016503)
0.0 0.1 GO:0032408 MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408)
0.0 0.1 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.0 0.1 GO:0052798 beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
0.0 0.3 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.2 GO:0032190 manganese ion transmembrane transporter activity(GO:0005384) acrosin binding(GO:0032190)
0.0 0.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 1.7 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.4 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.5 GO:0005549 odorant binding(GO:0005549)
0.0 0.1 GO:1990405 protein antigen binding(GO:1990405)
0.0 0.1 GO:0061769 ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769)
0.0 0.2 GO:0019841 retinol binding(GO:0019841)
0.0 0.2 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.1 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.0 0.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 2.0 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.1 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.0 0.7 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.2 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.1 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.4 GO:0001848 complement binding(GO:0001848)
0.0 0.2 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.2 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 1.6 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.3 PID IL23 PATHWAY IL23-mediated signaling events
0.0 1.2 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.3 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 1.7 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 4.7 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.5 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 1.0 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.5 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 1.4 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.5 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.3 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.3 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.4 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.2 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.4 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.3 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.7 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction