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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for SOX18

Z-value: 0.49

Motif logo

Transcription factors associated with SOX18

Gene Symbol Gene ID Gene Info
ENSG00000203883.7 SOX18

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX18hg38_v1_chr20_-_64049631_64049646-0.291.7e-01Click!

Activity profile of SOX18 motif

Sorted Z-values of SOX18 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX18

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr4_-_76023489 2.09 ENST00000306602.3
C-X-C motif chemokine ligand 10
chr17_+_43006740 1.39 ENST00000438323.2
ENST00000415816.7
interferon induced protein 35
chr1_-_150765735 1.30 ENST00000679898.1
ENST00000448301.7
ENST00000680664.1
ENST00000679512.1
ENST00000368985.8
ENST00000679582.1
cathepsin S
chr6_-_128520358 1.12 ENST00000368215.7
ENST00000532331.5
ENST00000368213.9
ENST00000368207.7
ENST00000525459.1
ENST00000368226.9
ENST00000368210.7
protein tyrosine phosphatase receptor type K
chr11_+_5689780 0.74 ENST00000379965.8
ENST00000454828.5
tripartite motif containing 22
chr11_-_117876719 0.72 ENST00000529335.6
ENST00000260282.8
FXYD domain containing ion transport regulator 6
chr7_-_93148345 0.67 ENST00000437805.5
ENST00000446959.5
ENST00000439952.5
ENST00000414791.5
ENST00000446033.1
ENST00000411955.5
ENST00000318238.9
sterile alpha motif domain containing 9 like
chr13_-_33205997 0.64 ENST00000399365.7
StAR related lipid transfer domain containing 13
chr6_-_134318097 0.61 ENST00000367858.10
ENST00000533224.1
serum/glucocorticoid regulated kinase 1
chr11_-_117876892 0.57 ENST00000539526.5
FXYD domain containing ion transport regulator 6
chr4_-_113979635 0.53 ENST00000315366.8
arylsulfatase family member J
chr21_-_30372265 0.53 ENST00000399889.4
keratin associated protein 13-2
chr19_+_8052752 0.51 ENST00000315626.6
ENST00000253451.9
C-C motif chemokine ligand 25
chr10_+_68721012 0.50 ENST00000536391.5
ENST00000630771.2
cell division cycle and apoptosis regulator 1
chr12_+_14973020 0.48 ENST00000266395.3
phosphodiesterase 6H
chr21_-_30813270 0.47 ENST00000329621.6
keratin associated protein 8-1
chr5_-_67196791 0.44 ENST00000256447.5
CD180 molecule
chr19_+_8053000 0.42 ENST00000390669.7
C-C motif chemokine ligand 25
chr1_-_247458105 0.41 ENST00000641149.1
ENST00000641527.1
olfactory receptor family 2 subfamily B member 11
chr11_-_117876612 0.41 ENST00000584230.1
ENST00000526014.6
ENST00000584394.5
ENST00000614497.5
ENST00000532984.1
FXYD domain containing ion transport regulator 6
FXYD6-FXYD2 readthrough
chr11_-_34357994 0.40 ENST00000435224.3
ankyrin repeat and BTB domain containing 2
chr14_+_94110728 0.39 ENST00000616764.4
ENST00000618863.1
ENST00000611954.4
ENST00000618200.4
ENST00000621160.4
ENST00000555819.5
ENST00000620396.4
ENST00000612813.4
ENST00000620066.1
interferon alpha inducible protein 27
chr19_-_14835162 0.38 ENST00000322301.5
olfactory receptor family 7 subfamily A member 5
chr7_-_122699108 0.36 ENST00000340112.3
ring finger protein 133
chr13_-_28100556 0.36 ENST00000241453.12
fms related receptor tyrosine kinase 3
chr3_-_112975018 0.35 ENST00000471858.5
ENST00000308611.8
ENST00000295863.4
CD200 receptor 1
chr2_-_37671633 0.35 ENST00000295324.4
CDC42 effector protein 3
chr2_-_210303608 0.34 ENST00000341685.8
myosin light chain 1
chr1_+_171185293 0.33 ENST00000209929.10
flavin containing dimethylaniline monoxygenase 2
chr11_+_13277639 0.33 ENST00000527998.5
ENST00000529388.6
ENST00000401424.6
ENST00000403510.8
ENST00000403290.6
ENST00000533520.5
ENST00000389707.8
ENST00000673817.1
aryl hydrocarbon receptor nuclear translocator like
chr11_+_196761 0.31 ENST00000325113.9
outer dense fiber of sperm tails 3
chr3_+_19148500 0.30 ENST00000328405.7
potassium voltage-gated channel subfamily H member 8
chr19_+_39655907 0.29 ENST00000392051.4
galectin 16
chr3_+_111998739 0.28 ENST00000393917.6
ENST00000273368.8
transgelin 3
chr20_+_45857607 0.27 ENST00000255152.3
zinc finger SWIM-type containing 3
chr13_-_51845169 0.27 ENST00000627246.3
ENST00000629372.3
transmembrane protein 272
chr13_-_46142834 0.27 ENST00000674665.1
lymphocyte cytosolic protein 1
chr11_-_85686123 0.26 ENST00000316398.5
coiled-coil domain containing 89
chr8_-_13276491 0.26 ENST00000512044.6
DLC1 Rho GTPase activating protein
chr22_-_38794111 0.26 ENST00000406622.5
ENST00000216068.9
ENST00000406199.3
Sad1 and UNC84 domain containing 2
dynein axonemal light chain 4
chr2_+_100974849 0.26 ENST00000450763.1
neuronal PAS domain protein 2
chr19_-_633500 0.25 ENST00000588649.7
RNA polymerase mitochondrial
chr11_+_89926762 0.25 ENST00000526396.3
tripartite motif containing 49D2
chr12_-_11092313 0.25 ENST00000531678.1
taste 2 receptor member 43
chr3_+_111998915 0.24 ENST00000478951.6
transgelin 3
chr11_+_74988896 0.24 ENST00000526068.1
ENST00000294064.9
ENST00000532963.1
ENST00000531619.1
ENST00000534628.1
neuraminidase 3
chr19_-_56836047 0.23 ENST00000601070.5
zinc finger imprinted 2
chr15_-_64825608 0.23 ENST00000559239.2
ENST00000268043.8
ENST00000333425.10
PIF1 5'-to-3' DNA helicase
chr3_-_146460440 0.22 ENST00000610787.5
phospholipid scramblase 2
chr12_-_14938508 0.21 ENST00000266397.7
endoplasmic reticulum protein 27
chr1_-_94927079 0.21 ENST00000370206.9
ENST00000394202.8
calponin 3
chr6_+_24126186 0.20 ENST00000378478.5
ENST00000378491.9
ENST00000378477.2
neurensin 1
chr5_-_137499293 0.20 ENST00000510689.5
ENST00000394945.6
SPARC (osteonectin), cwcv and kazal like domains proteoglycan 1
chr4_-_122456725 0.20 ENST00000226730.5
interleukin 2
chr3_+_156674579 0.20 ENST00000295924.12
TCDD inducible poly(ADP-ribose) polymerase
chr12_+_104303726 0.19 ENST00000527879.2
EP300 interacting inhibitor of differentiation 3
chr4_+_26321192 0.19 ENST00000681484.1
recombination signal binding protein for immunoglobulin kappa J region
chr15_+_67125707 0.19 ENST00000540846.6
SMAD family member 3
chr4_+_26321365 0.19 ENST00000505958.6
recombination signal binding protein for immunoglobulin kappa J region
chr4_-_99563668 0.19 ENST00000273962.7
tRNA methyltransferase 10A
chr13_-_46182136 0.19 ENST00000323076.7
lymphocyte cytosolic protein 1
chr1_+_3021466 0.19 ENST00000378404.4
actin related protein T2
chr8_+_24294044 0.19 ENST00000265769.9
ADAM metallopeptidase domain 28
chr12_-_110445540 0.18 ENST00000547365.1
actin related protein 2/3 complex subunit 3
chr7_+_6009222 0.18 ENST00000400479.6
ENST00000223029.8
ENST00000395236.2
aminoacyl tRNA synthetase complex interacting multifunctional protein 2
chr5_-_59356962 0.18 ENST00000405755.6
phosphodiesterase 4D
chr19_+_44072142 0.18 ENST00000421176.4
zinc finger protein 284
chr3_+_57756230 0.18 ENST00000295951.7
ENST00000659705.1
ENST00000671191.1
sarcolemma associated protein
chr2_-_37672178 0.17 ENST00000457889.1
CDC42 effector protein 3
chr11_-_102625332 0.17 ENST00000260228.3
matrix metallopeptidase 20
chr4_+_7043315 0.16 ENST00000310074.8
ENST00000512388.1
transcriptional adaptor 2B
chr3_+_127193131 0.16 ENST00000624688.2
chromosome 3 open reading frame 56
chr15_+_21651844 0.16 ENST00000623441.1
olfactory receptor family 4 subfamily N member 4C
chrX_-_111412162 0.16 ENST00000637570.1
ENST00000356220.8
ENST00000636035.2
ENST00000637453.1
ENST00000635795.1
doublecortin
chr14_+_92794297 0.16 ENST00000163416.7
golgin A5
chr11_+_60040402 0.15 ENST00000278855.7
ENST00000532905.1
oocyte secreted protein 2
chr5_-_79512794 0.15 ENST00000282260.10
ENST00000508576.5
ENST00000535690.1
homer scaffold protein 1
chr20_+_841238 0.15 ENST00000541082.2
family with sequence similarity 110 member A
chr7_+_142111739 0.15 ENST00000550469.6
ENST00000477922.3
maltase-glucoamylase 2 (putative)
chr19_-_50639827 0.15 ENST00000593901.5
ENST00000600079.6
synaptotagmin 3
chr7_+_142511614 0.15 ENST00000390377.1
T cell receptor beta variable 7-7
chr4_-_67883987 0.15 ENST00000283916.11
transmembrane serine protease 11D
chr15_-_80252205 0.15 ENST00000560778.3
cortexin domain containing 1
chr3_-_24495532 0.15 ENST00000643772.1
ENST00000642307.1
ENST00000645139.1
thyroid hormone receptor beta
chr9_-_21351378 0.15 ENST00000380210.1
interferon alpha 6
chr12_-_69699353 0.15 ENST00000331471.8
bestrophin 3
chr3_-_121660892 0.15 ENST00000428394.6
ENST00000314583.8
hematopoietic cell-specific Lyn substrate 1
chr12_-_69699331 0.15 ENST00000548658.1
ENST00000476098.5
bestrophin 3
chr5_-_43515128 0.14 ENST00000306862.7
chromosome 5 open reading frame 34
chr11_-_119095456 0.14 ENST00000530167.1
H2A.X variant histone
chr17_-_75855204 0.14 ENST00000589642.5
ENST00000593002.1
ENST00000590221.5
ENST00000587374.5
ENST00000585462.5
ENST00000254806.8
ENST00000433525.6
ENST00000626827.2
WW domain binding protein 2
chr11_+_124184244 0.14 ENST00000641546.1
olfactory receptor family 10 subfamily D member 3
chr4_+_85604146 0.14 ENST00000512201.5
Rho GTPase activating protein 24
chr13_-_44161257 0.14 ENST00000400419.2
small integral membrane protein 2
chr17_-_41140487 0.14 ENST00000345847.4
keratin associated protein 4-6
chr5_+_32711723 0.14 ENST00000415167.2
natriuretic peptide receptor 3
chr12_-_11310420 0.14 ENST00000621732.4
ENST00000445719.2
ENST00000279575.7
proline rich protein BstNI subfamily 4
chr5_+_157180816 0.14 ENST00000422843.8
IL2 inducible T cell kinase
chr1_-_72100930 0.14 ENST00000306821.3
neuronal growth regulator 1
chrX_-_132961390 0.13 ENST00000370836.6
ENST00000521489.5
heparan sulfate 6-O-sulfotransferase 2
chr15_-_55249029 0.13 ENST00000566877.5
RAB27A, member RAS oncogene family
chr12_+_64824602 0.13 ENST00000539867.6
ENST00000544457.1
ENST00000539120.1
TBC1 domain family member 30
chr12_-_95996302 0.13 ENST00000261208.8
ENST00000538703.5
ENST00000541929.5
histidine ammonia-lyase
chr18_-_5396265 0.13 ENST00000579951.2
erythrocyte membrane protein band 4.1 like 3
chr19_+_36111151 0.13 ENST00000633214.1
ENST00000585332.3
ovo like zinc finger 3
chr9_-_134917872 0.12 ENST00000616356.4
ENST00000371806.4
ficolin 1
chr5_+_159263282 0.12 ENST00000296786.8
ubiquitin like domain containing CTD phosphatase 1
chr7_-_149028452 0.12 ENST00000413966.1
ENST00000652332.1
protein disulfide isomerase family A member 4
chr2_+_201260510 0.12 ENST00000673742.1
caspase 8
chr2_+_201260496 0.12 ENST00000323492.11
caspase 8
chr15_+_22094522 0.12 ENST00000328795.5
olfactory receptor family 4 subfamily N member 4
chr7_-_149028651 0.12 ENST00000286091.9
protein disulfide isomerase family A member 4
chr3_-_36993103 0.12 ENST00000322716.8
EPM2A interacting protein 1
chrX_+_120362079 0.12 ENST00000539306.5
ENST00000218008.8
ENST00000361319.3
ATPase Na+/K+ transporting family member beta 4
chr14_-_106675544 0.12 ENST00000390632.2
immunoglobulin heavy variable 3-66
chrX_+_30243715 0.12 ENST00000378981.8
ENST00000397550.6
MAGE family member B1
chr3_-_71064915 0.12 ENST00000614176.5
ENST00000485326.7
forkhead box P1
chr11_-_118176576 0.12 ENST00000278947.6
sodium voltage-gated channel beta subunit 2
chr1_-_11858935 0.12 ENST00000376468.4
natriuretic peptide B
chr12_-_11395556 0.11 ENST00000565533.1
ENST00000389362.6
ENST00000546254.3
proline rich protein BstNI subfamily 2
proline rich protein BstNI subfamily 1
chrX_+_120604084 0.11 ENST00000371317.10
MCTS1 re-initiation and release factor
chr1_+_13060769 0.11 ENST00000617807.3
heterogeneous nuclear ribonucleoprotein C like 3
chr7_+_142598016 0.11 ENST00000620773.1
T cell receptor beta variable 16
chr3_-_71064964 0.11 ENST00000650387.1
forkhead box P1
chr12_-_49605634 0.11 ENST00000257894.2
family with sequence similarity 186 member B
chr14_+_21768482 0.11 ENST00000390428.3
T cell receptor alpha variable 6
chr19_+_48271327 0.11 ENST00000594024.5
ENST00000595408.5
ENST00000315849.5
zinc finger protein 114
chr5_-_142644201 0.11 ENST00000394496.2
ENST00000610990.4
fibroblast growth factor 1
chr8_+_24294107 0.11 ENST00000437154.6
ADAM metallopeptidase domain 28
chr12_+_32679200 0.11 ENST00000452533.6
ENST00000414834.6
dynamin 1 like
chr8_-_85341705 0.11 ENST00000517618.5
carbonic anhydrase 1
chr4_+_109815503 0.11 ENST00000394631.7
GAR1 ribonucleoprotein
chr11_+_65181920 0.10 ENST00000279247.11
ENST00000532285.1
ENST00000534373.5
calpain 1
chr4_+_3441960 0.10 ENST00000382774.8
ENST00000511533.1
HGF activator
chr1_-_153540694 0.10 ENST00000368717.2
S100 calcium binding protein A5
chr14_+_35046238 0.10 ENST00000280987.9
family with sequence similarity 177 member A1
chr15_-_42491105 0.10 ENST00000565380.5
ENST00000564754.7
zinc finger protein 106
chr8_-_21812320 0.10 ENST00000517328.5
GDNF family receptor alpha 2
chr17_-_17281232 0.10 ENST00000417352.5
ENST00000268717.10
COP9 signalosome subunit 3
chr8_+_117135259 0.10 ENST00000519688.5
solute carrier family 30 member 8
chr12_-_2876986 0.10 ENST00000342628.6
ENST00000361953.7
forkhead box M1
chr3_-_112974912 0.10 ENST00000440122.6
ENST00000490004.1
CD200 receptor 1
chr1_-_165445220 0.10 ENST00000619224.1
retinoid X receptor gamma
chr1_+_179954740 0.10 ENST00000491495.2
ENST00000367607.8
centrosomal protein 350
chr5_+_44808930 0.09 ENST00000507110.6
mitochondrial ribosomal protein S30
chr1_+_13303539 0.09 ENST00000437300.2
PRAME family member 33
chr1_-_248645278 0.09 ENST00000641268.1
olfactory receptor family 2 subfamily T member 35
chr16_-_28356654 0.09 ENST00000533640.5
nuclear pore complex interacting protein family member B6
chr2_+_53767772 0.09 ENST00000295304.5
ChaC glutathione specific gamma-glutamylcyclotransferase 2
chr12_+_69359673 0.09 ENST00000548020.5
ENST00000549685.5
ENST00000247843.7
ENST00000552955.1
YEATS domain containing 4
chr8_-_86743626 0.09 ENST00000320005.6
cyclic nucleotide gated channel subunit beta 3
chr2_+_3658193 0.09 ENST00000252505.4
allantoicase
chr6_-_169250825 0.09 ENST00000676869.1
ENST00000676760.1
thrombospondin 2
chr1_-_156248084 0.09 ENST00000652405.1
ENST00000335852.6
ENST00000540423.5
ENST00000612424.4
ENST00000613336.4
ENST00000623241.3
progestin and adipoQ receptor family member 6
chr17_+_28371656 0.09 ENST00000585482.6
sterile alpha and TIR motif containing 1
chr12_-_262828 0.09 ENST00000343164.9
ENST00000436453.1
ENST00000445055.6
ENST00000546319.5
solute carrier family 6 member 13
chr7_-_135977308 0.09 ENST00000435723.1
ENST00000393085.4
myotrophin
chr1_+_153031195 0.09 ENST00000307098.5
small proline rich protein 1B
chr22_+_42553862 0.09 ENST00000340239.8
ENST00000327678.10
serine hydrolase like 2
chr16_+_33827140 0.08 ENST00000562905.2
immunoglobulin heavy variable 3/OR16-13 (non-functional)
chr15_-_40874216 0.08 ENST00000220507.5
ras homolog family member V
chr11_-_105023136 0.08 ENST00000526056.5
ENST00000531367.5
ENST00000456094.1
ENST00000444749.6
ENST00000393141.6
ENST00000418434.5
ENST00000260315.8
caspase 5
chr19_-_19733091 0.08 ENST00000344099.4
zinc finger protein 14
chr10_+_84424919 0.08 ENST00000543283.2
ENST00000494586.5
coiled-coil serine rich protein 2
chr12_+_69239592 0.08 ENST00000456847.7
ENST00000266679.8
cleavage and polyadenylation specific factor 6
chr10_-_104232301 0.08 ENST00000369720.6
ENST00000369719.2
ENST00000278064.7
ENST00000357060.8
cilia and flagella associated protein 43
chr18_+_35041387 0.08 ENST00000538170.6
ENST00000300249.10
ENST00000588910.5
microtubule associated protein RP/EB family member 2
chr13_-_83882390 0.08 ENST00000377084.3
SLIT and NTRK like family member 1
chrX_-_47145035 0.08 ENST00000276062.8
NADH:ubiquinone oxidoreductase subunit B11
chr3_-_151461011 0.08 ENST00000282466.4
immunoglobulin superfamily member 10
chr20_-_37095985 0.08 ENST00000344359.7
ENST00000373664.8
RB transcriptional corepressor like 1
chr12_-_2877113 0.08 ENST00000627656.2
ENST00000359843.8
forkhead box M1
chr2_+_105337515 0.08 ENST00000410049.1
ENST00000258457.7
chromosome 2 open reading frame 49
chr19_+_7049321 0.08 ENST00000381393.3
methyl-CpG binding domain protein 3 like 2
chr11_+_65182413 0.08 ENST00000531068.5
ENST00000527699.5
ENST00000533909.5
ENST00000527323.5
calpain 1
chrX_-_49184789 0.08 ENST00000453382.5
ENST00000432913.5
prickle planar cell polarity protein 3
chr1_-_12898270 0.08 ENST00000235347.4
PRAME family member 10
chr5_-_138213308 0.08 ENST00000394886.7
ENST00000505120.1
ENST00000394884.7
cell division cycle 23
chr19_-_35745391 0.07 ENST00000378975.8
ENST00000587886.2
ENST00000412391.6
ENST00000292879.9
U2 small nuclear RNA auxiliary factor 1 like 4
chr1_+_160081529 0.07 ENST00000368088.4
potassium inwardly rectifying channel subfamily J member 9
chr12_-_69699285 0.07 ENST00000553096.5
ENST00000330891.10
bestrophin 3
chr1_-_157777124 0.07 ENST00000361516.8
ENST00000368181.4
Fc receptor like 2
chr12_+_69239560 0.07 ENST00000435070.7
cleavage and polyadenylation specific factor 6
chrX_+_47193796 0.07 ENST00000442035.5
ENST00000335972.11
ENST00000457753.5
ubiquitin like modifier activating enzyme 1
chr5_-_98928992 0.07 ENST00000614616.5
chromodomain helicase DNA binding protein 1
chr6_-_31158073 0.07 ENST00000507751.5
ENST00000448162.6
ENST00000502557.5
ENST00000503420.5
ENST00000507892.1
ENST00000507226.1
ENST00000513222.1
ENST00000503934.5
ENST00000396263.6
ENST00000508683.5
ENST00000428174.1
ENST00000448141.6
ENST00000507829.5
ENST00000455279.6
ENST00000376266.9
coiled-coil alpha-helical rod protein 1
chr1_-_156248038 0.07 ENST00000470198.5
ENST00000292291.10
ENST00000356983.7
progestin and adipoQ receptor family member 6
chr9_+_35791570 0.07 ENST00000342694.7
natriuretic peptide receptor 2
chr2_+_44275457 0.07 ENST00000611973.4
ENST00000409387.5
solute carrier family 3 member 1
chr1_+_201780490 0.07 ENST00000430015.5
neuron navigator 1
chr15_-_79090760 0.07 ENST00000419573.7
ENST00000558480.7
Ras protein specific guanine nucleotide releasing factor 1
chr7_-_93574721 0.07 ENST00000426151.7
ENST00000649521.1
calcitonin receptor
chr2_+_79025696 0.07 ENST00000272324.10
regenerating family member 3 gamma
chr9_-_125484490 0.07 ENST00000444226.1
MAPK associated protein 1
chr11_+_124183219 0.07 ENST00000641351.2
olfactory receptor family 10 subfamily D member 3
chr1_-_156248013 0.06 ENST00000368270.2
progestin and adipoQ receptor family member 6
chr14_-_106811131 0.06 ENST00000424969.2
immunoglobulin heavy variable 3-74
chr8_+_54616078 0.06 ENST00000220676.2
RP1 axonemal microtubule associated
chr8_-_85341659 0.06 ENST00000522389.5
carbonic anhydrase 1
chr9_-_96302142 0.06 ENST00000648799.1
hydroxysteroid 17-beta dehydrogenase 3

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0034769 basement membrane disassembly(GO:0034769)
0.2 2.1 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.1 0.9 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.1 0.6 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.1 0.3 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.1 0.3 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.1 0.6 GO:0070294 renal sodium ion absorption(GO:0070294)
0.1 0.4 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.1 0.2 GO:0039513 modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
0.1 0.7 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 1.1 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.1 0.4 GO:1901189 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 0.2 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.4 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.0 0.1 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.0 0.3 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.2 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.0 0.2 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.0 0.2 GO:1903630 regulation of aminoacyl-tRNA ligase activity(GO:1903630)
0.0 0.1 GO:0090149 synaptic vesicle recycling via endosome(GO:0036466) mitochondrial membrane fission(GO:0090149)
0.0 0.4 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.5 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.1 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.2 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.0 0.2 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.0 0.3 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.0 GO:0045917 positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
0.0 0.1 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.0 0.1 GO:0043606 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.0 0.1 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.0 0.2 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.1 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0 0.5 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.1 GO:0043605 cellular amide catabolic process(GO:0043605)
0.0 0.1 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.0 0.2 GO:0007619 courtship behavior(GO:0007619) female courtship behavior(GO:0008050)
0.0 0.1 GO:0044278 cell wall disruption in other organism(GO:0044278)
0.0 1.8 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0 0.2 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.3 GO:0070234 positive regulation of T cell apoptotic process(GO:0070234)
0.0 0.3 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.3 GO:0051775 response to redox state(GO:0051775)
0.0 0.0 GO:0030185 nitric oxide transport(GO:0030185)
0.0 0.1 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.0 0.3 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.0 0.1 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.0 0.1 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.2 GO:0060056 mammary gland involution(GO:0060056)
0.0 0.1 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.0 0.1 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 2.0 GO:0071357 type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0 0.1 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.1 GO:0001865 NK T cell differentiation(GO:0001865)
0.0 0.1 GO:0034127 regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034127) negative regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034128)
0.0 0.5 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.0 0.1 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.2 GO:0070170 regulation of tooth mineralization(GO:0070170)
0.0 0.2 GO:2000781 positive regulation of double-strand break repair(GO:2000781)
0.0 0.1 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.2 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.1 GO:0060467 negative regulation of fertilization(GO:0060467)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.3 GO:0036021 endolysosome lumen(GO:0036021)
0.0 0.4 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.2 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.2 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 0.2 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.3 GO:0033391 chromatoid body(GO:0033391)
0.0 0.4 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.3 GO:0001520 outer dense fiber(GO:0001520)
0.0 0.1 GO:0005953 CAAX-protein geranylgeranyltransferase complex(GO:0005953)
0.0 0.2 GO:0042382 paraspeckles(GO:0042382)
0.0 0.1 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.0 0.1 GO:0090661 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.0 0.5 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.1 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.0 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 1.4 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.2 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.1 GO:0089701 U2AF(GO:0089701)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.1 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.2 0.9 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.2 0.5 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.1 0.2 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116)
0.1 0.3 GO:0030395 lactose binding(GO:0030395)
0.1 0.2 GO:0004339 glucan 1,4-alpha-glucosidase activity(GO:0004339)
0.0 0.2 GO:0052794 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.3 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.1 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.0 1.1 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.2 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.2 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.6 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.2 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 2.4 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.2 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.0 0.3 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.4 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 1.3 GO:0043394 proteoglycan binding(GO:0043394)
0.0 0.2 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.0 0.1 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.1 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.0 0.7 GO:0005521 lamin binding(GO:0005521)
0.0 0.4 GO:0000150 recombinase activity(GO:0000150)
0.0 0.3 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.1 GO:0016841 ammonia-lyase activity(GO:0016841)
0.0 0.1 GO:0004662 CAAX-protein geranylgeranyltransferase activity(GO:0004662)
0.0 0.1 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.0 0.1 GO:0004948 calcitonin receptor activity(GO:0004948)
0.0 0.2 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.0 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.0 0.1 GO:0004447 iodide peroxidase activity(GO:0004447)
0.0 0.1 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0 0.5 GO:0047555 cGMP binding(GO:0030553) 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.1 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.1 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.1 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.2 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.0 0.1 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.1 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.2 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.2 GO:0070324 thyroid hormone binding(GO:0070324)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 2.2 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 0.6 PID CONE PATHWAY Visual signal transduction: Cones
0.0 1.3 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.7 PID PI3KCI PATHWAY Class I PI3K signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.6 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 2.2 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.2 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 2.0 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.6 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.4 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.2 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10