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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for SOX4

Z-value: 0.74

Motif logo

Transcription factors associated with SOX4

Gene Symbol Gene ID Gene Info
ENSG00000124766.7 SOX4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX4hg38_v1_chr6_+_21593742_215937570.582.2e-03Click!

Activity profile of SOX4 motif

Sorted Z-values of SOX4 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX4

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr20_-_40689228 3.10 ENST00000373313.3
MAF bZIP transcription factor B
chr18_+_6729698 3.04 ENST00000383472.9
Rho GTPase activating protein 28
chr4_-_185956348 2.71 ENST00000431902.5
ENST00000284776.11
ENST00000415274.5
sorbin and SH3 domain containing 2
chr8_-_80080816 2.07 ENST00000520527.5
ENST00000517427.5
ENST00000379097.7
ENST00000448733.3
tumor protein D52
chr22_+_19760714 2.04 ENST00000649276.2
T-box transcription factor 1
chr5_-_111756245 1.65 ENST00000447165.6
neuronal regeneration related protein
chr4_-_158159657 1.63 ENST00000590648.5
golgi associated kinase 1B
chr3_+_141386393 1.53 ENST00000503809.5
zinc finger and BTB domain containing 38
chr2_+_69013170 1.51 ENST00000303714.9
ANTXR cell adhesion molecule 1
chr16_+_30395400 1.49 ENST00000320159.2
ENST00000613509.2
zinc finger protein 48
chrX_-_63785510 1.48 ENST00000437457.6
ENST00000374878.5
ENST00000623517.3
Cdc42 guanine nucleotide exchange factor 9
chr12_+_93569814 1.40 ENST00000340600.6
suppressor of cytokine signaling 2
chr17_-_64390852 1.39 ENST00000563924.6
platelet and endothelial cell adhesion molecule 1
chr11_-_10808304 1.36 ENST00000532082.6
eukaryotic translation initiation factor 4 gamma 2
chr2_-_75560893 1.28 ENST00000410113.5
ENST00000393913.8
eva-1 homolog A, regulator of programmed cell death
chr7_-_27180230 1.27 ENST00000396344.4
homeobox A10
chr12_+_101666203 1.25 ENST00000549608.1
myosin binding protein C1
chr14_+_75280078 1.18 ENST00000555347.1
Fos proto-oncogene, AP-1 transcription factor subunit
chr8_-_17722217 1.17 ENST00000381861.7
microtubule associated scaffold protein 1
chr5_-_39424966 1.16 ENST00000515700.5
ENST00000320816.11
ENST00000339788.10
DAB adaptor protein 2
chr10_+_18659382 1.14 ENST00000377275.4
ADP ribosylation factor like GTPase 5B
chr5_-_39425187 1.14 ENST00000545653.5
DAB adaptor protein 2
chr17_+_69502397 1.08 ENST00000613873.4
ENST00000589647.5
mitogen-activated protein kinase kinase 6
chr2_-_47155277 1.07 ENST00000294947.2
sperm-tail PG-rich repeat containing 4
chr1_+_185734362 1.06 ENST00000271588.9
hemicentin 1
chrX_-_63785149 1.06 ENST00000671741.2
ENST00000625116.3
ENST00000624355.1
Cdc42 guanine nucleotide exchange factor 9
chr5_+_141223332 1.01 ENST00000239449.7
ENST00000624896.1
ENST00000624396.1
protocadherin beta 14
novel protein
chr13_+_39038347 1.00 ENST00000379599.6
ENST00000379600.8
NHL repeat containing 3
chr15_+_24954912 0.99 ENST00000584968.5
ENST00000346403.10
ENST00000554227.6
ENST00000390687.9
ENST00000579070.5
ENST00000577565.1
ENST00000577949.5
ENST00000338327.4
small nuclear ribonucleoprotein polypeptide N
SNRPN upstream reading frame
chr20_+_32010429 0.97 ENST00000452892.3
ENST00000262659.12
CCM2 like scaffold protein
chr8_-_6563044 0.95 ENST00000338312.10
angiopoietin 2
chr1_+_96722628 0.92 ENST00000675401.1
polypyrimidine tract binding protein 2
chr11_+_114060204 0.91 ENST00000683318.1
zinc finger and BTB domain containing 16
chr16_-_15643024 0.89 ENST00000540441.6
meiosis regulator and mRNA stability factor 1
chr8_+_11802611 0.88 ENST00000623368.3
farnesyl-diphosphate farnesyltransferase 1
chr9_-_14313843 0.88 ENST00000636063.1
ENST00000380921.3
ENST00000622520.1
ENST00000380959.7
nuclear factor I B
chr13_+_39038292 0.88 ENST00000470258.5
NHL repeat containing 3
chr14_+_96039328 0.87 ENST00000553764.1
ENST00000555004.3
ENST00000556728.1
ENST00000553782.1
chromosome 14 open reading frame 132
chr5_+_141359970 0.87 ENST00000522605.2
ENST00000622527.1
protocadherin gamma subfamily B, 2
chr7_+_16753731 0.87 ENST00000262067.5
tetraspanin 13
chr17_+_27294076 0.84 ENST00000581440.5
ENST00000583742.1
ENST00000579733.5
ENST00000583193.5
ENST00000581185.5
ENST00000427287.6
ENST00000262394.7
ENST00000348811.6
WD repeat and SOCS box containing 1
chr13_-_100674787 0.83 ENST00000342624.10
transmembrane O-mannosyltransferase targeting cadherins 4
chr9_+_87498491 0.82 ENST00000622514.4
death associated protein kinase 1
chr4_+_77157189 0.82 ENST00000316355.10
ENST00000502280.5
cyclin G2
chr2_+_32946944 0.81 ENST00000404816.7
latent transforming growth factor beta binding protein 1
chr6_+_130366281 0.81 ENST00000617887.4
transmembrane protein 200A
chr8_-_6563238 0.80 ENST00000629816.3
ENST00000523120.2
angiopoietin 2
chr6_+_130365958 0.80 ENST00000296978.4
transmembrane protein 200A
chr12_+_32107151 0.77 ENST00000548411.5
BICD cargo adaptor 1
chr8_-_6563409 0.77 ENST00000325203.9
angiopoietin 2
chr7_+_116672187 0.76 ENST00000318493.11
ENST00000397752.8
MET proto-oncogene, receptor tyrosine kinase
chr2_-_105398978 0.72 ENST00000408995.5
ENST00000530340.6
ENST00000393353.7
ENST00000322142.13
ENST00000344213.9
ENST00000358129.8
four and a half LIM domains 2
chr14_+_91114431 0.71 ENST00000428926.6
ENST00000517362.5
D-glutamate cyclase
chr1_+_65992389 0.71 ENST00000423207.6
phosphodiesterase 4B
chr5_-_88877967 0.69 ENST00000508610.5
ENST00000636294.1
myocyte enhancer factor 2C
chr4_+_77158252 0.68 ENST00000395640.5
cyclin G2
chr14_+_91114667 0.68 ENST00000523894.5
ENST00000522322.5
ENST00000523771.5
D-glutamate cyclase
chr1_+_15758768 0.67 ENST00000483633.6
ENST00000502739.5
ENST00000375766.8
ENST00000431771.6
filamin binding LIM protein 1
chr9_-_123184233 0.63 ENST00000447404.6
spermatid perinuclear RNA binding protein
chr14_+_91114364 0.62 ENST00000518868.5
D-glutamate cyclase
chr2_-_69961624 0.58 ENST00000320256.6
aspartic peptidase retroviral like 1
chr8_+_11802667 0.57 ENST00000443614.6
ENST00000220584.9
ENST00000525900.5
farnesyl-diphosphate farnesyltransferase 1
chr14_-_50561119 0.57 ENST00000555216.5
mitogen-activated protein kinase kinase kinase kinase 5
chr22_+_26621952 0.55 ENST00000354760.4
crystallin beta A4
chr19_-_17264718 0.55 ENST00000431146.6
ENST00000594190.5
USH1 protein network component harmonin binding protein 1
chr19_+_1249870 0.54 ENST00000591446.6
midnolin
chr9_-_72364504 0.52 ENST00000237937.7
ENST00000343431.6
ENST00000376956.3
zinc finger AN1-type containing 5
chr9_-_16727980 0.52 ENST00000418777.5
ENST00000468187.6
basonuclin 2
chr19_+_1248553 0.50 ENST00000586757.5
ENST00000300952.6
ENST00000682408.1
midnolin
chr1_-_182672232 0.49 ENST00000508450.5
regulator of G protein signaling 8
chr17_+_59220446 0.48 ENST00000284116.9
ENST00000581140.5
ENST00000581276.5
glycerophosphodiester phosphodiesterase domain containing 1
chr7_+_116210501 0.48 ENST00000455989.1
ENST00000358204.9
testin LIM domain protein
chr7_-_108003122 0.44 ENST00000393559.2
ENST00000222399.11
ENST00000676777.1
ENST00000439976.6
ENST00000393560.5
ENST00000677793.1
ENST00000679244.1
laminin subunit beta 1
chr20_-_17531366 0.44 ENST00000377873.8
beaded filament structural protein 1
chr1_+_93448155 0.42 ENST00000370253.6
formin binding protein 1 like
chr6_-_75206044 0.41 ENST00000322507.13
collagen type XII alpha 1 chain
chr5_+_102865805 0.39 ENST00000346918.7
peptidylglycine alpha-amidating monooxygenase
chr9_+_136327424 0.39 ENST00000616132.4
G protein signaling modulator 1
chr6_+_43014103 0.39 ENST00000244670.12
ENST00000326974.9
ENST00000332245.9
kelch domain containing 3
chr5_+_87267792 0.38 ENST00000274376.11
RAS p21 protein activator 1
chr9_-_83921405 0.38 ENST00000297814.7
ENST00000334204.6
ENST00000413982.5
kinesin family member 27
chr11_-_95232514 0.38 ENST00000634898.1
ENST00000542176.1
ENST00000278499.6
sestrin 3
chr14_+_69191475 0.38 ENST00000409018.7
ENST00000409014.5
ENST00000409675.5
exonuclease 3'-5' domain containing 2
chrX_-_24672654 0.38 ENST00000379145.5
phosphate cytidylyltransferase 1, choline, beta
chr15_+_65530754 0.38 ENST00000566074.5
3-hydroxyacyl-CoA dehydratase 3
chr19_-_17264732 0.38 ENST00000252597.8
USH1 protein network component harmonin binding protein 1
chr9_-_72365198 0.36 ENST00000376962.10
ENST00000376960.8
zinc finger AN1-type containing 5
chr15_+_65530418 0.36 ENST00000562901.5
ENST00000261875.10
ENST00000442729.6
ENST00000565299.5
ENST00000568793.5
3-hydroxyacyl-CoA dehydratase 3
chr16_+_3018390 0.34 ENST00000573001.5
TNF receptor superfamily member 12A
chr1_-_32336224 0.33 ENST00000329421.8
MARCKS like 1
chr7_+_139829153 0.33 ENST00000652056.1
thromboxane A synthase 1
chr1_+_150067279 0.32 ENST00000643970.1
ENST00000535106.5
ENST00000369128.9
vacuolar protein sorting 45 homolog
chr11_-_102452758 0.32 ENST00000398136.7
ENST00000361236.7
transmembrane protein 123
chr22_-_38084093 0.32 ENST00000681075.1
solute carrier family 16 member 8
chr7_+_80638662 0.30 ENST00000394788.7
CD36 molecule
chr10_+_22316445 0.30 ENST00000448361.5
COMM domain containing 3
chr8_-_42501224 0.30 ENST00000520262.6
ENST00000517366.1
solute carrier family 20 member 2
chr10_+_22316375 0.30 ENST00000376836.8
ENST00000456711.5
ENST00000444869.5
ENST00000475460.6
ENST00000602390.5
ENST00000489125.2
COMM domain containing 3
COMMD3-BMI1 readthrough
chr7_+_80638510 0.29 ENST00000433696.6
ENST00000538969.5
ENST00000544133.5
CD36 molecule
chr3_+_50611871 0.28 ENST00000446044.5
MAPK activated protein kinase 3
chr14_+_69191760 0.28 ENST00000409949.5
ENST00000312994.9
ENST00000409242.5
ENST00000413191.1
exonuclease 3'-5' domain containing 2
chr2_+_222671651 0.28 ENST00000446656.4
monoacylglycerol O-acyltransferase 1
chr9_-_36401198 0.28 ENST00000377885.6
ring finger protein 38
chr20_+_35954564 0.28 ENST00000622112.4
ENST00000614708.1
cyclic nucleotide binding domain containing 2
chr9_-_36400860 0.28 ENST00000377877.4
ENST00000357058.7
ENST00000350199.8
ring finger protein 38
chrX_+_52184874 0.27 ENST00000599522.7
ENST00000471932.6
MAGE family member D4
chr14_+_49768109 0.26 ENST00000298307.10
ENST00000554589.5
ENST00000557247.1
kelch domain containing 2
chr14_-_20454741 0.26 ENST00000206542.9
ENST00000553640.3
O-sialoglycoprotein endopeptidase
chr7_+_80638633 0.26 ENST00000447544.7
ENST00000482059.6
CD36 molecule
chr2_-_20225433 0.26 ENST00000381150.5
syndecan 1
chr16_-_3880678 0.26 ENST00000262367.10
CREB binding protein
chr17_+_9162935 0.26 ENST00000436734.1
netrin 1
chr1_+_27934980 0.26 ENST00000373894.8
sphingomyelin phosphodiesterase acid like 3B
chr18_+_58863580 0.25 ENST00000586085.5
ENST00000589288.5
zinc finger protein 532
chr8_+_10054269 0.25 ENST00000317173.9
ENST00000441698.6
methionine sulfoxide reductase A
chr17_+_75456618 0.25 ENST00000314256.12
ENST00000582186.5
ENST00000582455.5
ENST00000581252.5
ENST00000579208.5
transmembrane protein 94
chr8_-_16186270 0.25 ENST00000445506.6
macrophage scavenger receptor 1
chrX_+_12975083 0.25 ENST00000451311.7
ENST00000380636.1
thymosin beta 4 X-linked
chr2_+_207559168 0.24 ENST00000448277.5
ENST00000457101.5
cAMP responsive element binding protein 1
chr11_-_62646598 0.24 ENST00000648273.1
ENST00000356638.8
ENST00000346178.8
ENST00000534779.5
ENST00000525994.1
ENST00000540933.5
glucosidase II alpha subunit
chr3_+_159852933 0.24 ENST00000482804.1
schwannomin interacting protein 1
chr15_-_60479080 0.24 ENST00000560072.5
ENST00000560406.5
ENST00000560520.1
ENST00000261520.9
interactor of little elongation complex ELL subunit 2
chr7_-_100081701 0.23 ENST00000292393.9
ENST00000299667.9
ENST00000413658.6
ENST00000441298.5
ENST00000449785.5
ENST00000412947.6
zinc finger protein 3
chr7_-_19773569 0.23 ENST00000422233.5
ENST00000433641.5
ENST00000405844.6
transmembrane protein 196
chr5_+_141370236 0.23 ENST00000576222.2
ENST00000618934.1
protocadherin gamma subfamily B, 3
chr11_-_102843597 0.23 ENST00000299855.10
matrix metallopeptidase 3
chr16_+_474850 0.22 ENST00000450428.5
ENST00000452814.5
RAB11 family interacting protein 3
chrX_-_136880715 0.22 ENST00000431446.7
ENST00000320676.11
ENST00000562646.5
RNA binding motif protein X-linked
chr1_+_27935110 0.21 ENST00000549094.1
sphingomyelin phosphodiesterase acid like 3B
chr3_-_50611767 0.21 ENST00000443053.6
ENST00000348721.4
cytokine inducible SH2 containing protein
chr1_+_100351698 0.21 ENST00000644676.1
cell division cycle 14A
chr20_-_35954461 0.20 ENST00000305978.7
SCAN domain containing 1
chr17_-_76570544 0.20 ENST00000640006.1
novel protein
chr4_+_105708772 0.20 ENST00000512828.1
ENST00000394730.7
ENST00000515279.6
ENST00000507281.5
glutathione S-transferase C-terminal domain containing
chr11_+_7251886 0.20 ENST00000318881.11
synaptotagmin 9
chr2_+_97669739 0.20 ENST00000599501.6
ENST00000627399.3
ENST00000627284.2
ENST00000599435.5
ENST00000597654.5
ENST00000598737.5
chromosome 2 open reading frame 92
chr3_+_179148341 0.20 ENST00000263967.4
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
chr5_+_141182369 0.20 ENST00000609684.3
ENST00000625044.1
ENST00000623407.1
ENST00000623884.1
protocadherin beta 16
novel transcript
chrX_+_12975216 0.20 ENST00000380635.5
thymosin beta 4 X-linked
chr11_+_57763820 0.19 ENST00000674106.1
catenin delta 1
chr16_+_72054477 0.19 ENST00000355906.10
ENST00000570083.5
ENST00000228226.12
ENST00000398131.6
ENST00000569639.5
ENST00000564499.5
ENST00000357763.8
ENST00000613898.1
ENST00000562526.5
ENST00000565574.5
ENST00000568417.6
haptoglobin
chr11_-_61792581 0.18 ENST00000537328.6
transmembrane protein 258
chr12_+_109477368 0.18 ENST00000434735.6
ubiquitin protein ligase E3B
chr14_-_73027117 0.17 ENST00000318876.9
zinc finger FYVE-type containing 1
chr1_-_225653045 0.17 ENST00000366843.6
ENST00000366844.7
ENAH actin regulator
chr1_+_8318088 0.17 ENST00000471889.7
solute carrier family 45 member 1
chr1_+_93179883 0.17 ENST00000343253.11
coiled-coil domain containing 18
chr14_-_73027077 0.17 ENST00000553891.5
ENST00000556143.6
zinc finger FYVE-type containing 1
chr5_+_141387698 0.16 ENST00000615384.1
ENST00000519479.2
protocadherin gamma subfamily B, 4
chr20_+_18145083 0.16 ENST00000489634.2
lysine acetyltransferase 14
chr1_+_153967864 0.16 ENST00000449724.5
ENST00000368607.8
ENST00000271889.8
cAMP responsive element binding protein 3 like 4
chr9_-_39239174 0.16 ENST00000358144.6
contactin associated protein family member 3
chr1_-_1307861 0.15 ENST00000354700.10
ArfGAP with coiled-coil, ankyrin repeat and PH domains 3
chr7_-_5529949 0.15 ENST00000642480.2
ENST00000417101.2
actin beta
chr9_-_71768386 0.15 ENST00000377066.9
ENST00000377044.9
cell migration inducing hyaluronidase 2
chr16_+_6019585 0.15 ENST00000547372.5
RNA binding fox-1 homolog 1
chr3_-_100114488 0.15 ENST00000477258.2
ENST00000354552.7
ENST00000331335.9
ENST00000398326.2
filamin A interacting protein 1 like
chr4_-_53558199 0.14 ENST00000306888.6
ligand of numb-protein X 1
chr4_+_158768955 0.14 ENST00000264433.11
folliculin interacting protein 2
chr12_-_10130241 0.14 ENST00000353231.9
ENST00000525605.1
C-type lectin domain containing 7A
chr5_+_141408032 0.14 ENST00000520790.1
protocadherin gamma subfamily B, 6
chr1_+_160177386 0.14 ENST00000470705.1
ATPase Na+/K+ transporting subunit alpha 4
chr12_+_8513499 0.13 ENST00000299665.3
C-type lectin domain family 4 member D
chr12_-_10130082 0.13 ENST00000533022.5
C-type lectin domain containing 7A
chr12_-_10130143 0.13 ENST00000298523.9
ENST00000396484.6
ENST00000310002.4
ENST00000304084.13
C-type lectin domain containing 7A
chr6_-_27472681 0.13 ENST00000377419.1
zinc finger protein 184
chr19_+_48624952 0.13 ENST00000599748.5
ENST00000599029.2
sphingosine kinase 2
chr12_-_95551417 0.13 ENST00000258499.8
ubiquitin specific peptidase 44
chr8_+_79611727 0.12 ENST00000518491.1
stathmin 2
chr1_+_27935022 0.12 ENST00000411604.5
ENST00000373888.8
sphingomyelin phosphodiesterase acid like 3B
chr16_+_72063226 0.12 ENST00000540303.7
ENST00000356967.6
ENST00000561690.1
haptoglobin-related protein
chr1_-_25906931 0.12 ENST00000357865.6
stathmin 1
chr14_+_23969874 0.11 ENST00000534993.5
ENST00000543805.6
ENST00000558293.7
dehydrogenase/reductase 4 like 2
novel transcript
chr6_+_87344812 0.11 ENST00000388923.5
chromosome 6 open reading frame 163
chrX_+_71283577 0.11 ENST00000420903.6
ENST00000373856.8
ENST00000678437.1
ENST00000678830.1
ENST00000677879.1
ENST00000373841.5
ENST00000276079.13
ENST00000676797.1
ENST00000678660.1
ENST00000678231.1
ENST00000677612.1
ENST00000413858.5
ENST00000450092.6
non-POU domain containing octamer binding
chr10_-_11532275 0.11 ENST00000277575.5
USP6 N-terminal like
chr15_+_90872862 0.11 ENST00000618099.4
furin, paired basic amino acid cleaving enzyme
chr16_-_31073712 0.11 ENST00000414399.1
zinc finger protein 668
chr17_-_10469558 0.11 ENST00000255381.2
myosin heavy chain 4
chr15_-_44195210 0.11 ENST00000402883.5
ENST00000417257.6
FERM domain containing 5
chr7_+_116672357 0.10 ENST00000456159.1
MET proto-oncogene, receptor tyrosine kinase
chr6_+_139135063 0.10 ENST00000367658.3
hdc homolog, cell cycle regulator
chr4_-_22443110 0.10 ENST00000508133.5
adhesion G protein-coupled receptor A3
chr1_-_93180261 0.10 ENST00000370280.1
ENST00000479918.5
transmembrane p24 trafficking protein 5
chr17_+_29246852 0.10 ENST00000225387.8
crystallin beta A1
chrX_-_41923547 0.10 ENST00000378163.7
calcium/calmodulin dependent serine protein kinase
chr17_-_5123102 0.10 ENST00000250076.7
zinc finger protein 232
chr2_-_70768175 0.09 ENST00000355733.7
ENST00000447731.6
ENST00000430656.5
ENST00000264436.9
ENST00000413157.6
adducin 2
chr14_-_31207469 0.09 ENST00000556224.5
HECT domain E3 ubiquitin protein ligase 1
chr7_-_100081758 0.09 ENST00000424697.5
zinc finger protein 3
chr6_-_27473058 0.09 ENST00000683788.1
ENST00000211936.10
zinc finger protein 184
chr16_+_6019071 0.09 ENST00000547605.5
ENST00000553186.5
RNA binding fox-1 homolog 1
chr14_+_20455210 0.09 ENST00000557344.5
ENST00000216714.8
ENST00000398030.8
ENST00000557181.5
ENST00000555839.5
ENST00000553368.1
ENST00000556054.5
ENST00000557054.1
ENST00000557592.5
ENST00000557150.5
apurinic/apyrimidinic endodeoxyribonuclease 1
chr6_+_43298254 0.09 ENST00000372585.10
ENST00000449231.5
ENST00000372589.7
solute carrier family 22 member 7
chr22_-_31292445 0.08 ENST00000402249.7
ENST00000215912.10
ENST00000443175.1
ENST00000441972.5
phosphoinositide-3-kinase interacting protein 1
chr2_+_171687457 0.08 ENST00000397119.8
ENST00000410079.7
ENST00000438879.5
dynein cytoplasmic 1 intermediate chain 2
chr1_+_153968237 0.08 ENST00000368601.5
ENST00000368603.5
ENST00000368600.7
cAMP responsive element binding protein 3 like 4
chr15_-_72272530 0.08 ENST00000569795.6
ENST00000566844.1
poly(ADP-ribose) polymerase family member 6
chr14_+_20455185 0.08 ENST00000555414.5
ENST00000553681.5
apurinic/apyrimidinic endodeoxyribonuclease 1
chr6_+_41072939 0.07 ENST00000341376.11
ENST00000353205.5
nuclear transcription factor Y subunit alpha

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.5 GO:0050928 negative regulation of positive chemotaxis(GO:0050928)
0.8 3.1 GO:0021571 rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.8 2.3 GO:0035026 leading edge cell differentiation(GO:0035026)
0.7 2.0 GO:1902809 regulation of skeletal muscle fiber differentiation(GO:1902809)
0.4 1.1 GO:0072709 cellular response to sorbitol(GO:0072709)
0.3 1.4 GO:0050904 diapedesis(GO:0050904) glomerular endothelium development(GO:0072011)
0.3 1.0 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.3 1.5 GO:1901202 negative regulation of extracellular matrix assembly(GO:1901202)
0.2 1.5 GO:0006696 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.2 3.0 GO:1904424 regulation of GTP binding(GO:1904424)
0.2 0.7 GO:0055011 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.2 0.9 GO:0051138 positive regulation of NK T cell differentiation(GO:0051138)
0.1 1.2 GO:0001661 conditioned taste aversion(GO:0001661)
0.1 1.0 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1 0.8 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.1 0.4 GO:0018032 protein amidation(GO:0018032)
0.1 0.9 GO:2000334 response to linoleic acid(GO:0070543) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.1 0.7 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.1 0.3 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 0.7 GO:0003138 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.1 1.0 GO:0070495 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495) negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.1 0.9 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.1 1.2 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.1 0.3 GO:0048627 myoblast development(GO:0048627)
0.1 0.2 GO:2000296 regulation of hydrogen peroxide catabolic process(GO:2000295) negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.1 0.2 GO:1904550 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.1 1.4 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.1 2.2 GO:0061049 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 0.4 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.1 0.2 GO:0097698 telomere maintenance via base-excision repair(GO:0097698)
0.1 0.7 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 0.7 GO:0033623 regulation of integrin activation(GO:0033623)
0.1 0.3 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.1 0.2 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.0 0.3 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0 0.8 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.6 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.3 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.2 GO:2000653 regulation of genetic imprinting(GO:2000653)
0.0 0.2 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0 0.1 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0 1.4 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.1 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.0 0.4 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.1 GO:1900276 regulation of proteinase activated receptor activity(GO:1900276) negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900737)
0.0 1.2 GO:0060065 uterus development(GO:0060065)
0.0 0.2 GO:0010727 negative regulation of hydrogen peroxide metabolic process(GO:0010727)
0.0 0.1 GO:0006669 sphinganine-1-phosphate biosynthetic process(GO:0006669)
0.0 0.4 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.3 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.2 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.0 0.1 GO:0019082 viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.0 0.3 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.3 GO:0015727 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.0 0.4 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.3 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.0 0.3 GO:0030091 protein repair(GO:0030091)
0.0 1.1 GO:0033119 negative regulation of RNA splicing(GO:0033119)
0.0 0.5 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.0 0.3 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.1 GO:0005989 lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989)
0.0 0.9 GO:0007143 female meiotic division(GO:0007143)
0.0 0.7 GO:0000729 DNA double-strand break processing(GO:0000729)
0.0 0.3 GO:0044351 macropinocytosis(GO:0044351)
0.0 0.6 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.3 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.7 GO:0003016 respiratory system process(GO:0003016)
0.0 0.5 GO:0043586 tongue development(GO:0043586)
0.0 0.1 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.4 GO:0042832 defense response to protozoan(GO:0042832)
0.0 0.4 GO:0003351 epithelial cilium movement(GO:0003351)
0.0 0.4 GO:0097320 membrane tubulation(GO:0097320)
0.0 0.0 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.1 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0 1.1 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.1 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.3 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 1.2 GO:0035976 AP1 complex(GO:0035976)
0.1 0.4 GO:0005606 laminin-1 complex(GO:0005606)
0.1 0.4 GO:0005595 collagen type XII trimer(GO:0005595)
0.1 0.3 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.1 1.0 GO:0005687 U4 snRNP(GO:0005687)
0.1 1.1 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 2.2 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.2 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.2 GO:0035363 histone locus body(GO:0035363)
0.0 1.4 GO:0032982 myosin filament(GO:0032982)
0.0 0.2 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.3 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 1.5 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.1 GO:0072517 viral factory(GO:0039713) cytoplasmic viral factory(GO:0039714) host cell viral assembly compartment(GO:0072517)
0.0 0.8 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.9 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.2 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.7 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.4 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.9 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.2 GO:0060091 kinocilium(GO:0060091)
0.0 0.0 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.0 0.4 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 1.3 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 1.9 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.2 GO:0005915 zonula adherens(GO:0005915)
0.0 0.7 GO:0031430 M band(GO:0031430)
0.0 0.5 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.1 GO:1990769 proximal neuron projection(GO:1990769)
0.0 0.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.2 GO:0097433 dense body(GO:0097433)
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)
0.0 2.2 GO:0030018 Z disc(GO:0030018)
0.0 0.2 GO:0031045 dense core granule(GO:0031045)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.5 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.2 1.4 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.2 0.8 GO:0050436 microfibril binding(GO:0050436)
0.1 0.3 GO:0004796 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.1 0.9 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.1 0.7 GO:0102344 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.1 0.4 GO:0004598 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.1 2.3 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 2.8 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.4 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 0.7 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.1 0.3 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.1 0.9 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 0.2 GO:0098918 structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.1 0.3 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 0.6 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 1.2 GO:0031432 titin binding(GO:0031432)
0.0 0.3 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.0 0.3 GO:0030492 hemoglobin binding(GO:0030492)
0.0 1.5 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.2 GO:0008311 double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.0 0.2 GO:1990763 arrestin family protein binding(GO:1990763)
0.0 0.7 GO:0003680 AT DNA binding(GO:0003680)
0.0 1.3 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.4 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.2 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.0 0.3 GO:0043426 MRF binding(GO:0043426)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.3 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.6 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.7 GO:0031005 filamin binding(GO:0031005)
0.0 0.7 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.8 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.2 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.1 GO:0008481 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.0 0.6 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.2 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.4 GO:0038187 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 1.2 GO:0070412 R-SMAD binding(GO:0070412)
0.0 1.6 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 1.0 GO:0030552 cAMP binding(GO:0030552)
0.0 0.3 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.2 GO:0035497 cAMP response element binding(GO:0035497)
0.0 1.1 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.1 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.2 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.4 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.3 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.9 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 2.1 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.5 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 1.5 GO:0005518 collagen binding(GO:0005518)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 2.5 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 2.2 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 2.5 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.1 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 1.6 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 2.6 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 1.6 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 2.0 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.2 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.9 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 0.7 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 1.0 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.9 PID HNF3A PATHWAY FOXA1 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.3 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 1.4 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.1 2.2 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 2.5 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 1.2 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 1.4 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.8 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 1.6 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 1.5 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.9 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 1.9 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.7 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.3 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 1.2 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.9 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.7 REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION Genes involved in Nuclear Events (kinase and transcription factor activation)
0.0 0.3 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 2.8 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.7 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 1.9 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.4 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC