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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for SOX5

Z-value: 1.37

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Transcription factors associated with SOX5

Gene Symbol Gene ID Gene Info
SOX5
ENSG00000134532.19 SOX5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX5hg38_v1_chr12_-_23951020_239510370.638.2e-04Click!

Activity profile of SOX5 motif

Sorted Z-values of SOX5 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX5

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr4_+_41612892 7.37 ENST00000509454.5
ENST00000396595.7
ENST00000381753.8
LIMCH1
LIM and calponin homology domains 1
chr4_+_41612702 6.94 ENST00000509277.5
LIMCH1
LIM and calponin homology domains 1
chr3_-_18424533 6.89 ENST00000417717.6
SATB1
SATB homeobox 1
chr2_-_187448244 6.85 ENST00000392370.8
ENST00000410068.5
ENST00000447403.5
ENST00000410102.5
CALCRL
calcitonin receptor like receptor
chr7_-_11832190 6.41 ENST00000423059.9
ENST00000617773.1
THSD7A
thrombospondin type 1 domain containing 7A
chr4_-_100517991 5.57 ENST00000511970.5
ENST00000502569.1
ENST00000305864.7
ENST00000296420.9
EMCN
endomucin
chrX_-_117973579 5.18 ENST00000371878.5
KLHL13
kelch like family member 13
chr18_+_44680875 4.94 ENST00000649279.2
ENST00000677699.1
SETBP1
SET binding protein 1
chr4_-_185810894 4.63 ENST00000448662.6
ENST00000439049.5
ENST00000420158.5
ENST00000319471.13
SORBS2
sorbin and SH3 domain containing 2
chr1_+_61081728 4.38 ENST00000371189.8
NFIA
nuclear factor I A
chr10_-_114684612 4.16 ENST00000533213.6
ENST00000369252.8
ABLIM1
actin binding LIM protein 1
chr21_+_17513003 3.97 ENST00000284878.12
ENST00000400166.5
CXADR
CXADR Ig-like cell adhesion molecule
chr9_-_14314519 3.97 ENST00000397581.6
NFIB
nuclear factor I B
chr2_-_156342348 3.96 ENST00000409572.5
NR4A2
nuclear receptor subfamily 4 group A member 2
chr9_-_14314567 3.94 ENST00000397579.6
NFIB
nuclear factor I B
chr14_-_91947654 3.70 ENST00000342058.9
FBLN5
fibulin 5
chr9_-_14314132 3.68 ENST00000380953.6
NFIB
nuclear factor I B
chr3_+_134795248 3.54 ENST00000398015.8
EPHB1
EPH receptor B1
chr9_-_131270493 3.52 ENST00000372269.7
ENST00000464831.1
FAM78A
family with sequence similarity 78 member A
chr14_-_91946989 3.49 ENST00000556154.5
FBLN5
fibulin 5
chr12_+_53050014 3.41 ENST00000314250.11
TNS2
tensin 2
chrX_-_117973717 3.32 ENST00000262820.7
KLHL13
kelch like family member 13
chr12_+_53050179 3.30 ENST00000546602.5
ENST00000552570.5
ENST00000549700.5
TNS2
tensin 2
chr14_-_91947383 3.18 ENST00000267620.14
FBLN5
fibulin 5
chr10_+_35126791 3.16 ENST00000474362.5
ENST00000374721.7
CREM
cAMP responsive element modulator
chr10_+_35127162 3.14 ENST00000354759.7
CREM
cAMP responsive element modulator
chr12_+_32502114 3.00 ENST00000682739.1
ENST00000427716.7
ENST00000583694.2
FGD4
FYVE, RhoGEF and PH domain containing 4
chr9_+_2159672 2.95 ENST00000634343.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr14_+_61187544 2.90 ENST00000555185.5
ENST00000557294.5
ENST00000556778.5
PRKCH
protein kinase C eta
chr1_+_185734362 2.84 ENST00000271588.9
HMCN1
hemicentin 1
chr10_+_35127023 2.63 ENST00000429130.7
ENST00000469949.6
ENST00000460270.5
CREM
cAMP responsive element modulator
chr12_-_85836372 2.55 ENST00000361228.5
RASSF9
Ras association domain family member 9
chr9_+_79573162 2.50 ENST00000425506.5
TLE4
TLE family member 4, transcriptional corepressor
chr1_+_164559739 2.47 ENST00000627490.2
PBX1
PBX homeobox 1
chr15_-_52652031 2.41 ENST00000546305.6
FAM214A
family with sequence similarity 214 member A
chr14_-_89417148 2.32 ENST00000557258.6
FOXN3
forkhead box N3
chr9_-_137302264 2.29 ENST00000356628.4
NRARP
NOTCH regulated ankyrin repeat protein
chr20_-_47356670 2.22 ENST00000540497.5
ENST00000461685.5
ENST00000617418.4
ENST00000435836.5
ENST00000471951.6
ENST00000352431.6
ENST00000360911.7
ENST00000458360.6
ZMYND8
zinc finger MYND-type containing 8
chr2_+_69013170 2.19 ENST00000303714.9
ANTXR1
ANTXR cell adhesion molecule 1
chr3_-_142028597 2.14 ENST00000467667.5
TFDP2
transcription factor Dp-2
chrX_+_136169624 2.13 ENST00000394153.6
FHL1
four and a half LIM domains 1
chr2_-_159616442 2.12 ENST00000541068.6
ENST00000392783.7
ENST00000392782.5
BAZ2B
bromodomain adjacent to zinc finger domain 2B
chr5_-_88785493 2.07 ENST00000503554.4
MEF2C
myocyte enhancer factor 2C
chrX_+_136169664 2.02 ENST00000456445.5
FHL1
four and a half LIM domains 1
chr10_+_35127295 1.95 ENST00000489321.5
ENST00000427847.6
ENST00000374728.7
ENST00000345491.7
ENST00000487132.5
CREM
cAMP responsive element modulator
chrX_+_136169833 1.94 ENST00000628032.2
FHL1
four and a half LIM domains 1
chr9_-_122227525 1.94 ENST00000373755.6
ENST00000373754.6
LHX6
LIM homeobox 6
chr20_-_47356721 1.93 ENST00000262975.8
ENST00000446994.6
ENST00000355972.8
ENST00000396281.8
ENST00000619049.4
ENST00000611941.4
ENST00000372023.7
ZMYND8
zinc finger MYND-type containing 8
chr9_-_15510954 1.89 ENST00000380733.9
PSIP1
PC4 and SFRS1 interacting protein 1
chr12_-_6124662 1.88 ENST00000261405.10
VWF
von Willebrand factor
chr3_+_134795277 1.82 ENST00000647596.1
EPHB1
EPH receptor B1
chr9_-_123268538 1.81 ENST00000360998.3
ENST00000348403.10
STRBP
spermatid perinuclear RNA binding protein
chr18_-_55510753 1.79 ENST00000543082.5
TCF4
transcription factor 4
chr7_-_32892015 1.79 ENST00000452926.1
KBTBD2
kelch repeat and BTB domain containing 2
chr3_+_124033356 1.71 ENST00000682506.1
KALRN
kalirin RhoGEF kinase
chr17_+_69502397 1.67 ENST00000613873.4
ENST00000589647.5
MAP2K6
mitogen-activated protein kinase kinase 6
chr2_-_110473041 1.65 ENST00000632897.1
ENST00000413601.3
LIMS4
LIM zinc finger domain containing 4
chr8_+_67952028 1.61 ENST00000288368.5
PREX2
phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2
chr3_-_65597886 1.61 ENST00000460329.6
MAGI1
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr21_+_17513119 1.58 ENST00000356275.10
ENST00000400165.5
ENST00000400169.1
CXADR
CXADR Ig-like cell adhesion molecule
chr20_+_33562306 1.57 ENST00000344201.7
CBFA2T2
CBFA2/RUNX1 partner transcriptional co-repressor 2
chrX_+_9912434 1.56 ENST00000418909.6
SHROOM2
shroom family member 2
chr3_-_142028617 1.56 ENST00000477292.5
ENST00000478006.5
ENST00000495310.5
ENST00000486111.5
TFDP2
transcription factor Dp-2
chr17_-_64390852 1.55 ENST00000563924.6
PECAM1
platelet and endothelial cell adhesion molecule 1
chr3_-_71305986 1.53 ENST00000647614.1
FOXP1
forkhead box P1
chr21_-_38498415 1.52 ENST00000398905.5
ENST00000398907.5
ENST00000453032.6
ENST00000288319.12
ERG
ETS transcription factor ERG
chr2_+_109898685 1.52 ENST00000480744.2
LIMS3
LIM zinc finger domain containing 3
chr5_+_139341826 1.49 ENST00000265192.9
PAIP2
poly(A) binding protein interacting protein 2
chr3_+_25428233 1.47 ENST00000437042.6
ENST00000330688.9
RARB
retinoic acid receptor beta
chr2_+_202634960 1.44 ENST00000392238.3
FAM117B
family with sequence similarity 117 member B
chr9_-_15510991 1.42 ENST00000380715.5
ENST00000380716.8
ENST00000380738.8
PSIP1
PC4 and SFRS1 interacting protein 1
chr6_+_118894144 1.42 ENST00000229595.6
ASF1A
anti-silencing function 1A histone chaperone
chr20_-_47355657 1.42 ENST00000311275.11
ZMYND8
zinc finger MYND-type containing 8
chr18_-_55321640 1.40 ENST00000637169.2
TCF4
transcription factor 4
chr1_+_33256479 1.37 ENST00000539719.6
ENST00000483388.5
ZNF362
zinc finger protein 362
chr4_+_169660062 1.32 ENST00000507875.5
ENST00000613795.4
CLCN3
chloride voltage-gated channel 3
chr9_-_69672341 1.32 ENST00000265381.7
APBA1
amyloid beta precursor protein binding family A member 1
chr5_+_139341875 1.32 ENST00000511706.5
PAIP2
poly(A) binding protein interacting protein 2
chrX_-_100636799 1.30 ENST00000373020.9
TSPAN6
tetraspanin 6
chr12_-_70637405 1.30 ENST00000548122.2
ENST00000551525.5
ENST00000550358.5
ENST00000334414.11
PTPRB
protein tyrosine phosphatase receptor type B
chr20_+_325536 1.29 ENST00000342665.5
SOX12
SRY-box transcription factor 12
chr14_-_21536884 1.28 ENST00000546363.5
SALL2
spalt like transcription factor 2
chr7_+_77538027 1.24 ENST00000433369.6
ENST00000415482.6
PTPN12
protein tyrosine phosphatase non-receptor type 12
chr6_+_155216637 1.23 ENST00000275246.11
TIAM2
TIAM Rac1 associated GEF 2
chr18_-_55321986 1.21 ENST00000570287.6
TCF4
transcription factor 4
chr9_+_27109393 1.18 ENST00000406359.8
TEK
TEK receptor tyrosine kinase
chr3_+_141386862 1.18 ENST00000513258.5
ZBTB38
zinc finger and BTB domain containing 38
chr13_-_74133892 1.16 ENST00000377669.7
KLF12
Kruppel like factor 12
chr12_+_59664677 1.15 ENST00000548610.5
SLC16A7
solute carrier family 16 member 7
chr10_-_14572123 1.15 ENST00000378465.7
ENST00000452706.6
ENST00000622567.4
ENST00000378458.6
FAM107B
family with sequence similarity 107 member B
chr2_-_163735989 1.11 ENST00000333129.4
ENST00000409634.5
FIGN
fidgetin, microtubule severing factor
chr3_+_141387616 1.08 ENST00000509883.5
ZBTB38
zinc finger and BTB domain containing 38
chr6_-_79234619 1.06 ENST00000344726.9
ENST00000275036.11
HMGN3
high mobility group nucleosomal binding domain 3
chr9_-_95509241 1.05 ENST00000331920.11
PTCH1
patched 1
chrX_+_108439779 1.05 ENST00000328300.11
COL4A5
collagen type IV alpha 5 chain
chr1_-_182391363 1.04 ENST00000417584.6
GLUL
glutamate-ammonia ligase
chr1_-_52552994 1.04 ENST00000355809.4
ENST00000528642.5
ENST00000470626.1
ENST00000257177.9
ENST00000371544.7
TUT4
terminal uridylyl transferase 4
chr15_+_66702219 1.03 ENST00000288840.10
SMAD6
SMAD family member 6
chrX_+_108439866 1.03 ENST00000361603.7
COL4A5
collagen type IV alpha 5 chain
chr10_+_61901678 1.03 ENST00000644638.1
ENST00000681100.1
ENST00000279873.12
ARID5B
AT-rich interaction domain 5B
chr2_-_70248598 1.01 ENST00000445587.5
ENST00000433529.7
ENST00000415783.6
TIA1
TIA1 cytotoxic granule associated RNA binding protein
chr18_-_55322215 1.00 ENST00000457482.7
TCF4
transcription factor 4
chr6_-_79234713 1.00 ENST00000620514.1
HMGN3
high mobility group nucleosomal binding domain 3
chr10_+_96043394 1.00 ENST00000403870.7
ENST00000265992.9
ENST00000465148.3
CCNJ
cyclin J
chr2_-_70248454 1.00 ENST00000416149.6
ENST00000282574.8
TIA1
TIA1 cytotoxic granule associated RNA binding protein
chr6_+_122399621 0.99 ENST00000368455.9
HSF2
heat shock transcription factor 2
chr2_-_25982471 0.98 ENST00000264712.8
KIF3C
kinesin family member 3C
chr11_+_46381033 0.96 ENST00000359803.7
MDK
midkine
chr6_+_122399536 0.96 ENST00000452194.5
HSF2
heat shock transcription factor 2
chr19_-_19515542 0.96 ENST00000585580.4
TSSK6
testis specific serine kinase 6
chr6_+_36029082 0.94 ENST00000472333.1
MAPK14
mitogen-activated protein kinase 14
chr12_+_55966821 0.94 ENST00000553376.5
ENST00000440311.6
ENST00000266970.9
ENST00000354056.4
CDK2
cyclin dependent kinase 2
chr9_-_71768386 0.94 ENST00000377066.9
ENST00000377044.9
CEMIP2
cell migration inducing hyaluronidase 2
chr5_+_139308095 0.93 ENST00000515833.2
MATR3
matrin 3
chr9_-_120714457 0.92 ENST00000373930.4
MEGF9
multiple EGF like domains 9
chrX_-_101617921 0.91 ENST00000361910.9
ENST00000538627.5
ENST00000539247.5
ARMCX6
armadillo repeat containing X-linked 6
chr14_-_50561119 0.90 ENST00000555216.5
MAP4K5
mitogen-activated protein kinase kinase kinase kinase 5
chr10_+_97319250 0.90 ENST00000371021.5
FRAT1
FRAT regulator of WNT signaling pathway 1
chr3_-_69080350 0.88 ENST00000630585.1
ENST00000361055.9
ENST00000415609.6
ENST00000349511.8
UBA3
ubiquitin like modifier activating enzyme 3
chr11_+_46380746 0.86 ENST00000405308.6
MDK
midkine
chr2_+_69013379 0.86 ENST00000409349.7
ANTXR1
ANTXR cell adhesion molecule 1
chr11_-_82997477 0.86 ENST00000534301.5
RAB30
RAB30, member RAS oncogene family
chr14_-_23435652 0.86 ENST00000355349.4
MYH7
myosin heavy chain 7
chr5_-_38595396 0.85 ENST00000263409.8
LIFR
LIF receptor subunit alpha
chr3_-_48717166 0.83 ENST00000413654.5
ENST00000454335.5
ENST00000440424.5
ENST00000449610.5
ENST00000443964.1
ENST00000417896.1
ENST00000413298.5
ENST00000449563.5
ENST00000443853.5
ENST00000437427.5
ENST00000446860.5
ENST00000412850.5
ENST00000424035.1
ENST00000340879.8
ENST00000431721.6
ENST00000434860.1
ENST00000328631.10
ENST00000432678.6
IP6K2
inositol hexakisphosphate kinase 2
chr11_-_102452758 0.83 ENST00000398136.7
ENST00000361236.7
TMEM123
transmembrane protein 123
chr3_-_114624193 0.82 ENST00000481632.5
ZBTB20
zinc finger and BTB domain containing 20
chrX_-_112840815 0.82 ENST00000304758.5
ENST00000371959.9
AMOT
angiomotin
chr11_+_46381194 0.81 ENST00000533952.5
MDK
midkine
chr9_-_70869076 0.80 ENST00000677594.1
TRPM3
transient receptor potential cation channel subfamily M member 3
chr1_+_81306096 0.76 ENST00000370721.5
ENST00000370727.5
ENST00000370725.5
ENST00000370723.5
ENST00000370728.5
ENST00000370730.5
ADGRL2
adhesion G protein-coupled receptor L2
chr1_+_150364136 0.75 ENST00000369068.5
RPRD2
regulation of nuclear pre-mRNA domain containing 2
chr15_+_43792839 0.75 ENST00000409614.1
SERF2
small EDRK-rich factor 2
chr1_-_150268941 0.74 ENST00000369109.8
ENST00000236017.5
APH1A
aph-1 homolog A, gamma-secretase subunit
chr12_-_102480604 0.74 ENST00000392905.7
IGF1
insulin like growth factor 1
chr11_+_46380932 0.73 ENST00000441869.5
MDK
midkine
chr18_+_58864866 0.72 ENST00000588456.5
ENST00000591808.6
ENST00000589481.1
ENST00000591049.1
ZNF532
zinc finger protein 532
chr5_+_139342442 0.69 ENST00000394795.6
ENST00000510080.1
PAIP2
poly(A) binding protein interacting protein 2
chrX_-_50814095 0.69 ENST00000376020.8
SHROOM4
shroom family member 4
chr12_-_102197827 0.68 ENST00000329406.5
PMCH
pro-melanin concentrating hormone
chr1_+_206834347 0.68 ENST00000340758.7
IL19
interleukin 19
chr2_-_197675578 0.68 ENST00000295049.9
RFTN2
raftlin family member 2
chrX_-_64976500 0.68 ENST00000447788.6
ZC4H2
zinc finger C4H2-type containing
chr12_-_31590967 0.67 ENST00000354285.8
DENND5B
DENN domain containing 5B
chr1_-_85578345 0.66 ENST00000426972.8
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr3_+_189789672 0.65 ENST00000434928.5
TP63
tumor protein p63
chr16_-_1782526 0.64 ENST00000566339.6
SPSB3
splA/ryanodine receptor domain and SOCS box containing 3
chr10_+_21524670 0.64 ENST00000631589.1
MLLT10
MLLT10 histone lysine methyltransferase DOT1L cofactor
chrX_-_24672654 0.63 ENST00000379145.5
PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr1_+_150364621 0.63 ENST00000401000.8
RPRD2
regulation of nuclear pre-mRNA domain containing 2
chr6_+_43059857 0.63 ENST00000259708.7
ENST00000472792.1
ENST00000479388.5
ENST00000460283.1
ENST00000394056.6
KLC4
kinesin light chain 4
chr2_+_33436304 0.62 ENST00000402538.7
RASGRP3
RAS guanyl releasing protein 3
chr7_-_27165517 0.62 ENST00000396345.1
ENST00000343483.7
HOXA9
homeobox A9
chr6_+_89080739 0.62 ENST00000369472.1
ENST00000336032.4
PNRC1
proline rich nuclear receptor coactivator 1
chr16_+_1078781 0.61 ENST00000293897.5
SSTR5
somatostatin receptor 5
chr6_-_90296908 0.61 ENST00000537989.5
BACH2
BTB domain and CNC homolog 2
chrX_+_123960519 0.60 ENST00000455404.5
ENST00000218089.13
STAG2
stromal antigen 2
chr2_+_86720282 0.60 ENST00000283632.5
RMND5A
required for meiotic nuclear division 5 homolog A
chr17_+_39738317 0.59 ENST00000394211.7
GRB7
growth factor receptor bound protein 7
chr11_+_128694052 0.58 ENST00000527786.7
ENST00000534087.3
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr6_-_99425269 0.57 ENST00000647811.1
ENST00000481229.2
ENST00000369239.10
ENST00000681611.1
ENST00000681615.1
ENST00000438806.5
PNISR
PNN interacting serine and arginine rich protein
chr10_+_21524627 0.57 ENST00000651097.1
MLLT10
MLLT10 histone lysine methyltransferase DOT1L cofactor
chr2_-_199458689 0.57 ENST00000443023.5
SATB2
SATB homeobox 2
chr1_+_202193791 0.55 ENST00000367278.8
LGR6
leucine rich repeat containing G protein-coupled receptor 6
chr3_+_14947680 0.55 ENST00000435454.5
ENST00000323373.10
NR2C2
nuclear receptor subfamily 2 group C member 2
chr11_+_128693887 0.54 ENST00000281428.12
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr3_+_14947568 0.53 ENST00000413118.5
ENST00000425241.5
NR2C2
nuclear receptor subfamily 2 group C member 2
chr12_-_48570046 0.53 ENST00000301046.6
ENST00000549817.1
LALBA
lactalbumin alpha
chr6_+_50818701 0.53 ENST00000344788.7
TFAP2B
transcription factor AP-2 beta
chr1_+_200739542 0.53 ENST00000358823.6
CAMSAP2
calmodulin regulated spectrin associated protein family member 2
chr6_+_156777366 0.52 ENST00000636930.2
ARID1B
AT-rich interaction domain 1B
chr15_-_34318761 0.52 ENST00000290209.9
SLC12A6
solute carrier family 12 member 6
chr22_-_46537593 0.51 ENST00000262738.9
ENST00000674500.2
CELSR1
cadherin EGF LAG seven-pass G-type receptor 1
chrX_+_71283186 0.51 ENST00000535149.5
NONO
non-POU domain containing octamer binding
chrX_-_50814302 0.51 ENST00000289292.11
SHROOM4
shroom family member 4
chr1_+_226063466 0.50 ENST00000666609.1
ENST00000661429.1
H3-3A
H3.3 histone A
chr4_+_109827963 0.50 ENST00000317735.7
RRH
retinal pigment epithelium-derived rhodopsin homolog
chrX_-_107716401 0.50 ENST00000486554.1
ENST00000372390.8
TSC22D3
TSC22 domain family member 3
chr6_+_156777882 0.50 ENST00000350026.10
ENST00000647938.1
ENST00000674298.1
ARID1B
AT-rich interaction domain 1B
chr12_-_8662881 0.49 ENST00000433590.6
MFAP5
microfibril associated protein 5
chr7_-_32891744 0.49 ENST00000304056.9
KBTBD2
kelch repeat and BTB domain containing 2
chrX_-_17860707 0.49 ENST00000360011.5
RAI2
retinoic acid induced 2
chr1_+_28914614 0.47 ENST00000645184.1
EPB41
erythrocyte membrane protein band 4.1
chr8_+_102551583 0.46 ENST00000285402.4
ODF1
outer dense fiber of sperm tails 1
chr9_+_27109135 0.46 ENST00000519097.5
ENST00000615002.4
TEK
TEK receptor tyrosine kinase
chr3_+_19947316 0.46 ENST00000422242.1
RAB5A
RAB5A, member RAS oncogene family
chr15_-_37099306 0.45 ENST00000557796.6
ENST00000397620.6
MEIS2
Meis homeobox 2
chrX_+_21940693 0.45 ENST00000404933.7
ENST00000379404.5
SMS
spermine synthase
chr1_+_228149922 0.44 ENST00000366714.3
GJC2
gap junction protein gamma 2
chr9_+_27109200 0.44 ENST00000380036.10
TEK
TEK receptor tyrosine kinase
chr1_-_224433776 0.43 ENST00000678879.1
ENST00000651911.2
WDR26
WD repeat domain 26
chr1_-_150269051 0.42 ENST00000414276.6
ENST00000360244.8
APH1A
aph-1 homolog A, gamma-secretase subunit
chr1_-_151146643 0.42 ENST00000613223.1
SEMA6C
semaphorin 6C
chr15_+_98648502 0.41 ENST00000650285.1
ENST00000649865.1
IGF1R
insulin like growth factor 1 receptor
chr10_-_11611754 0.41 ENST00000609104.5
USP6NL
USP6 N-terminal like
chr3_-_115071333 0.41 ENST00000462705.5
ZBTB20
zinc finger and BTB domain containing 20
chr17_-_45432916 0.40 ENST00000290470.3
ARHGAP27
Rho GTPase activating protein 27
chr20_-_62427528 0.40 ENST00000252998.2
RBBP8NL
RBBP8 N-terminal like
chr18_+_3451647 0.40 ENST00000345133.9
ENST00000330513.10
ENST00000549546.5
TGIF1
TGFB induced factor homeobox 1
chr1_-_156248013 0.38 ENST00000368270.2
PAQR6
progestin and adipoQ receptor family member 6

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 5.4 GO:0099557 trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission(GO:0099557)
1.4 5.6 GO:1903756 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
1.3 4.0 GO:0021538 epithalamus development(GO:0021538) habenula development(GO:0021986)
1.1 5.5 GO:0098904 regulation of AV node cell action potential(GO:0098904)
1.1 11.6 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.9 10.4 GO:0048251 elastic fiber assembly(GO:0048251)
0.6 3.0 GO:1901202 negative regulation of extracellular matrix assembly(GO:1901202)
0.6 1.7 GO:0072709 cellular response to sorbitol(GO:0072709)
0.5 6.9 GO:0009744 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.5 3.4 GO:0030421 defecation(GO:0030421)
0.4 6.9 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.4 1.6 GO:0072011 diapedesis(GO:0050904) glomerular endothelium development(GO:0072011)
0.4 3.3 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.3 2.2 GO:0048014 Tie signaling pathway(GO:0048014)
0.3 1.3 GO:0048388 endosomal lumen acidification(GO:0048388)
0.3 1.1 GO:0010157 response to chlorate(GO:0010157)
0.3 2.9 GO:0034351 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.3 1.0 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.3 2.1 GO:0003172 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.3 2.3 GO:0014807 regulation of somitogenesis(GO:0014807)
0.3 1.5 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199) positive regulation of blood vessel remodeling(GO:2000504)
0.2 0.9 GO:0007113 endomitotic cell cycle(GO:0007113)
0.2 0.9 GO:0014724 regulation of twitch skeletal muscle contraction(GO:0014724)
0.2 0.4 GO:0051389 inactivation of MAPKK activity(GO:0051389)
0.2 6.7 GO:0014850 response to muscle activity(GO:0014850)
0.2 0.6 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
0.2 0.5 GO:1990523 bone regeneration(GO:1990523)
0.2 0.5 GO:0005988 lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989)
0.2 1.7 GO:0046959 habituation(GO:0046959) negative regulation of growth hormone secretion(GO:0060125)
0.2 12.2 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.2 0.9 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835) positive regulation of interleukin-12 secretion(GO:2001184)
0.2 0.9 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.2 0.8 GO:1904075 regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.1 1.9 GO:0021853 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.1 2.1 GO:0045176 apical protein localization(GO:0045176)
0.1 1.1 GO:0006848 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.1 0.8 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.1 3.8 GO:0072189 ureter development(GO:0072189)
0.1 2.1 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.1 0.4 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.1 4.3 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 1.2 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 1.0 GO:0097026 dendritic cell dendrite assembly(GO:0097026)
0.1 0.6 GO:0038169 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.1 2.1 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.1 0.8 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.1 1.0 GO:0003183 mitral valve development(GO:0003174) mitral valve morphogenesis(GO:0003183)
0.1 0.3 GO:2000616 negative regulation of histone H3-K9 acetylation(GO:2000616)
0.1 0.3 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.1 1.3 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.1 3.5 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.1 2.4 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.1 0.6 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.1 0.3 GO:0097274 ammonia homeostasis(GO:0097272) urea homeostasis(GO:0097274)
0.1 0.3 GO:0030047 actin modification(GO:0030047)
0.1 1.0 GO:2000587 negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.1 2.5 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.1 3.7 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1 1.3 GO:1901223 negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway(GO:0039532) negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.1 0.4 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.1 0.7 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.1 0.5 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.1 1.9 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.1 1.0 GO:0035092 sperm chromatin condensation(GO:0035092)
0.1 1.5 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.1 0.2 GO:0021658 rhombomere morphogenesis(GO:0021593) rhombomere 3 morphogenesis(GO:0021658)
0.1 6.0 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.1 0.3 GO:0031161 phosphatidylinositol catabolic process(GO:0031161)
0.1 0.6 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1 0.7 GO:0032596 protein transport into membrane raft(GO:0032596) dsRNA transport(GO:0033227)
0.1 1.2 GO:0007220 Notch receptor processing(GO:0007220)
0.1 0.8 GO:0007258 JUN phosphorylation(GO:0007258)
0.1 0.6 GO:0006657 CDP-choline pathway(GO:0006657)
0.1 0.4 GO:0008215 spermine metabolic process(GO:0008215)
0.1 1.1 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.1 0.5 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 0.8 GO:0045793 positive regulation of cell size(GO:0045793)
0.1 1.1 GO:0035855 megakaryocyte development(GO:0035855)
0.1 0.6 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.7 GO:0042074 cell migration involved in gastrulation(GO:0042074)
0.0 0.3 GO:0001865 NK T cell differentiation(GO:0001865)
0.0 0.1 GO:0021722 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.0 0.7 GO:1900038 negative regulation of cellular response to hypoxia(GO:1900038)
0.0 0.2 GO:0030070 insulin processing(GO:0030070)
0.0 12.2 GO:0031032 actomyosin structure organization(GO:0031032)
0.0 1.1 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0 0.3 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.2 GO:0060087 relaxation of vascular smooth muscle(GO:0060087)
0.0 0.7 GO:0042226 interleukin-6 biosynthetic process(GO:0042226)
0.0 0.6 GO:1904886 beta-catenin destruction complex disassembly(GO:1904886)
0.0 0.1 GO:0097155 fasciculation of sensory neuron axon(GO:0097155) fasciculation of motor neuron axon(GO:0097156)
0.0 0.5 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 6.1 GO:0000910 cytokinesis(GO:0000910)
0.0 0.1 GO:0021834 embryonic olfactory bulb interneuron precursor migration(GO:0021831) chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration(GO:0021834) apoptotic process involved in luteolysis(GO:0061364)
0.0 1.6 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 0.1 GO:0098903 regulation of membrane repolarization during action potential(GO:0098903)
0.0 0.1 GO:0016240 autophagosome docking(GO:0016240)
0.0 0.1 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.0 1.2 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 6.7 GO:0065004 protein-DNA complex assembly(GO:0065004)
0.0 0.7 GO:0006817 phosphate ion transport(GO:0006817)
0.0 1.0 GO:0060612 adipose tissue development(GO:0060612)
0.0 2.1 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.0 0.2 GO:0042659 regulation of cell fate specification(GO:0042659)
0.0 0.0 GO:0038031 non-canonical Wnt signaling pathway via MAPK cascade(GO:0038030) non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.0 4.0 GO:0007286 spermatid development(GO:0007286)
0.0 0.2 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.0 2.5 GO:1990823 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.0 0.4 GO:0035886 vascular smooth muscle cell differentiation(GO:0035886)
0.0 3.3 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.3 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.0 1.0 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 1.7 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.7 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.0 0.1 GO:0002399 MHC protein complex assembly(GO:0002396) MHC class II protein complex assembly(GO:0002399)
0.0 0.2 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 1.0 GO:0045638 negative regulation of myeloid cell differentiation(GO:0045638)
0.0 0.8 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.0 0.4 GO:0016048 detection of temperature stimulus(GO:0016048)
0.0 0.7 GO:0097435 fibril organization(GO:0097435)
0.0 0.1 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.0 0.2 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.7 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 5.2 GO:0001525 angiogenesis(GO:0001525)
0.0 0.4 GO:0010644 cell communication by electrical coupling(GO:0010644)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 10.4 GO:0071953 elastic fiber(GO:0071953)
0.4 11.6 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.3 0.9 GO:0097135 X chromosome(GO:0000805) cyclin E2-CDK2 complex(GO:0097135)
0.3 2.0 GO:0097165 nuclear stress granule(GO:0097165)
0.2 2.0 GO:0005587 collagen type IV trimer(GO:0005587)
0.2 0.6 GO:0034657 GID complex(GO:0034657)
0.2 5.5 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 1.2 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.1 6.6 GO:0005720 nuclear heterochromatin(GO:0005720)
0.1 1.2 GO:0070765 gamma-secretase complex(GO:0070765)
0.1 2.6 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.1 11.5 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 1.1 GO:0044294 dendritic growth cone(GO:0044294)
0.1 3.3 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.1 1.6 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 0.4 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.1 0.7 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.1 0.8 GO:0042382 paraspeckles(GO:0042382)
0.1 2.9 GO:0016514 SWI/SNF complex(GO:0016514)
0.1 3.0 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 4.1 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.4 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 1.0 GO:0097386 glial cell projection(GO:0097386)
0.0 1.6 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 6.7 GO:0031901 early endosome membrane(GO:0031901)
0.0 18.8 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.6 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 1.1 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.7 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.5 GO:0001520 outer dense fiber(GO:0001520)
0.0 0.1 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 1.1 GO:0099738 cell cortex region(GO:0099738)
0.0 3.5 GO:0005604 basement membrane(GO:0005604)
0.0 0.3 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.4 GO:0005922 connexon complex(GO:0005922)
0.0 1.4 GO:0016591 DNA-directed RNA polymerase II, holoenzyme(GO:0016591)
0.0 1.2 GO:0031941 filamentous actin(GO:0031941)
0.0 14.5 GO:0005925 focal adhesion(GO:0005925)
0.0 0.1 GO:0002079 inner acrosomal membrane(GO:0002079)
0.0 1.3 GO:0005871 kinesin complex(GO:0005871)
0.0 0.3 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 2.0 GO:0016363 nuclear matrix(GO:0016363)
0.0 1.2 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 6.7 GO:0016607 nuclear speck(GO:0016607)
0.0 0.6 GO:0008180 COP9 signalosome(GO:0008180)
0.0 2.5 GO:0072562 blood microparticle(GO:0072562)
0.0 1.3 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 0.2 GO:0000786 nucleosome(GO:0000786)
0.0 1.0 GO:0032588 trans-Golgi network membrane(GO:0032588)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 6.9 GO:0004948 calcitonin receptor activity(GO:0004948)
0.6 10.8 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.6 5.5 GO:0071253 connexin binding(GO:0071253)
0.5 5.4 GO:0008046 axon guidance receptor activity(GO:0008046)
0.5 2.9 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.4 1.1 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.3 1.3 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.3 1.0 GO:0016880 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.3 5.4 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.3 3.3 GO:0097100 supercoiled DNA binding(GO:0097100)
0.2 0.8 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923)
0.2 1.1 GO:0005119 smoothened binding(GO:0005119) hedgehog family protein binding(GO:0097108)
0.2 0.8 GO:0052836 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.2 2.0 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.2 0.8 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.2 5.4 GO:0046965 retinoid X receptor binding(GO:0046965)
0.2 4.6 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.6 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.1 0.4 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.1 5.6 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 0.5 GO:0004461 lactose synthase activity(GO:0004461)
0.1 0.6 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 0.6 GO:0004994 somatostatin receptor activity(GO:0004994)
0.1 2.1 GO:0003680 AT DNA binding(GO:0003680)
0.1 1.0 GO:0070697 activin receptor binding(GO:0070697)
0.1 0.9 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.1 1.6 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.1 0.8 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 1.3 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1 0.4 GO:1903763 gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.1 3.4 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 0.7 GO:0016403 dimethylargininase activity(GO:0016403)
0.1 3.1 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 2.5 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 13.1 GO:0005178 integrin binding(GO:0005178)
0.1 4.5 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.1 0.5 GO:0043426 MRF binding(GO:0043426)
0.1 0.9 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 2.1 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.1 2.9 GO:0030371 translation repressor activity(GO:0030371)
0.1 2.1 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.1 GO:0061609 fructose-1-phosphate aldolase activity(GO:0061609)
0.0 0.2 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.0 0.9 GO:0035173 histone kinase activity(GO:0035173)
0.0 0.5 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.1 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.0 19.2 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 1.0 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.2 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 1.4 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.5 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.5 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 4.2 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.7 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.3 GO:0008934 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.0 3.0 GO:0005518 collagen binding(GO:0005518)
0.0 0.4 GO:0045159 myosin II binding(GO:0045159)
0.0 0.4 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 1.4 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 2.2 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 2.1 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.1 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.5 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 1.8 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 1.3 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 1.0 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 7.7 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 1.3 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.8 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.0 2.5 GO:0044325 ion channel binding(GO:0044325)
0.0 0.7 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 5.1 GO:0003682 chromatin binding(GO:0003682)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 16.0 PID HNF3A PATHWAY FOXA1 transcription factor network
0.2 10.3 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 4.7 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 4.8 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.1 4.8 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.1 1.1 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.1 2.4 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.1 0.7 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.1 3.4 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.1 1.7 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.1 4.0 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.1 6.9 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 1.4 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 3.1 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.1 1.6 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.9 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 3.3 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.9 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 2.2 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 1.2 PID IGF1 PATHWAY IGF1 pathway
0.0 9.8 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.8 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 3.5 PID E2F PATHWAY E2F transcription factor network
0.0 0.8 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 5.2 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 2.7 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.8 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.8 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.9 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.7 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.6 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.9 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 3.7 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.2 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 0.9 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.3 11.6 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.3 3.3 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1 1.6 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.1 1.9 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 4.2 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.1 8.2 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 1.1 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 1.7 REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS Genes involved in NRIF signals cell death from the nucleus
0.1 7.2 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.1 5.9 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 2.6 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 1.8 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 7.9 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 5.5 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.1 0.4 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.1 1.5 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 1.9 REACTOME KINESINS Genes involved in Kinesins
0.0 0.8 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.5 REACTOME OPSINS Genes involved in Opsins
0.0 4.0 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.0 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.6 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 2.2 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 8.7 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 2.1 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.5 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.4 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.7 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.4 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.6 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.3 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.6 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis