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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for SOX6

Z-value: 0.62

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Transcription factors associated with SOX6

Gene Symbol Gene ID Gene Info
SOX6
ENSG00000110693.19 SOX6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX6hg38_v1_chr11_-_16408853_164088940.096.7e-01Click!

Activity profile of SOX6 motif

Sorted Z-values of SOX6 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX6

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr4_+_41612892 3.06 ENST00000509454.5
ENST00000396595.7
ENST00000381753.8
LIMCH1
LIM and calponin homology domains 1
chr4_+_41612702 3.02 ENST00000509277.5
LIMCH1
LIM and calponin homology domains 1
chr1_+_99646025 2.87 ENST00000263174.9
ENST00000605497.5
ENST00000615664.1
PALMD
palmdelphin
chr3_-_18424533 2.03 ENST00000417717.6
SATB1
SATB homeobox 1
chr4_-_185810894 1.78 ENST00000448662.6
ENST00000439049.5
ENST00000420158.5
ENST00000319471.13
SORBS2
sorbin and SH3 domain containing 2
chr16_-_46831043 1.24 ENST00000565112.1
C16orf87
chromosome 16 open reading frame 87
chr7_+_116672187 1.15 ENST00000318493.11
ENST00000397752.8
MET
MET proto-oncogene, receptor tyrosine kinase
chr20_-_40689228 1.14 ENST00000373313.3
MAFB
MAF bZIP transcription factor B
chr18_+_6729698 1.13 ENST00000383472.9
ARHGAP28
Rho GTPase activating protein 28
chr9_-_137302264 1.10 ENST00000356628.4
NRARP
NOTCH regulated ankyrin repeat protein
chr4_-_185956348 1.09 ENST00000431902.5
ENST00000284776.11
ENST00000415274.5
SORBS2
sorbin and SH3 domain containing 2
chr22_+_19760714 1.02 ENST00000649276.2
TBX1
T-box transcription factor 1
chrX_-_117973579 1.02 ENST00000371878.5
KLHL13
kelch like family member 13
chr14_-_50561119 0.96 ENST00000555216.5
MAP4K5
mitogen-activated protein kinase kinase kinase kinase 5
chr2_+_69013170 0.89 ENST00000303714.9
ANTXR1
ANTXR cell adhesion molecule 1
chr16_+_30395400 0.77 ENST00000320159.2
ENST00000613509.2
ZNF48
zinc finger protein 48
chr4_+_54657918 0.76 ENST00000412167.6
ENST00000288135.6
KIT
KIT proto-oncogene, receptor tyrosine kinase
chr1_+_228149922 0.72 ENST00000366714.3
GJC2
gap junction protein gamma 2
chr1_-_25906457 0.70 ENST00000426559.6
STMN1
stathmin 1
chr17_-_64390852 0.68 ENST00000563924.6
PECAM1
platelet and endothelial cell adhesion molecule 1
chr4_+_143381939 0.65 ENST00000505913.5
GAB1
GRB2 associated binding protein 1
chr13_-_100674774 0.61 ENST00000328767.9
TMTC4
transmembrane O-mannosyltransferase targeting cadherins 4
chr14_-_87993143 0.59 ENST00000622264.4
GALC
galactosylceramidase
chr14_+_103123452 0.58 ENST00000558056.1
ENST00000560869.6
TNFAIP2
TNF alpha induced protein 2
chr16_+_29455105 0.57 ENST00000567248.1
SLX1B
SLX1 homolog B, structure-specific endonuclease subunit
chr7_+_77538027 0.57 ENST00000433369.6
ENST00000415482.6
PTPN12
protein tyrosine phosphatase non-receptor type 12
chr17_+_69502397 0.56 ENST00000613873.4
ENST00000589647.5
MAP2K6
mitogen-activated protein kinase kinase 6
chr9_-_131270493 0.56 ENST00000372269.7
ENST00000464831.1
FAM78A
family with sequence similarity 78 member A
chr2_-_207167220 0.51 ENST00000421199.5
ENST00000457962.5
KLF7
Kruppel like factor 7
chr2_-_207166818 0.51 ENST00000423015.5
KLF7
Kruppel like factor 7
chr8_-_28386417 0.51 ENST00000521185.5
ENST00000520290.5
ENST00000344423.10
ZNF395
zinc finger protein 395
chr13_-_100674787 0.51 ENST00000342624.10
TMTC4
transmembrane O-mannosyltransferase targeting cadherins 4
chr8_-_6563044 0.50 ENST00000338312.10
ANGPT2
angiopoietin 2
chrX_-_45200895 0.50 ENST00000377934.4
DIPK2B
divergent protein kinase domain 2B
chr12_-_108826161 0.50 ENST00000546697.1
SSH1
slingshot protein phosphatase 1
chr7_+_102912983 0.50 ENST00000339431.9
ENST00000249377.4
LRRC17
leucine rich repeat containing 17
chr5_-_39425187 0.49 ENST00000545653.5
DAB2
DAB adaptor protein 2
chr5_+_141359970 0.49 ENST00000522605.2
ENST00000622527.1
PCDHGB2
protocadherin gamma subfamily B, 2
chr5_-_39424966 0.47 ENST00000515700.5
ENST00000320816.11
ENST00000339788.10
DAB2
DAB adaptor protein 2
chr5_-_88785493 0.47 ENST00000503554.4
MEF2C
myocyte enhancer factor 2C
chr1_+_182839338 0.47 ENST00000367549.4
DHX9
DExH-box helicase 9
chrX_-_45200828 0.47 ENST00000398000.7
DIPK2B
divergent protein kinase domain 2B
chr2_-_151828408 0.45 ENST00000295087.13
ARL5A
ADP ribosylation factor like GTPase 5A
chr5_+_141223332 0.45 ENST00000239449.7
ENST00000624896.1
ENST00000624396.1
PCDHB14
ENSG00000279983.1
protocadherin beta 14
novel protein
chr15_+_76931704 0.44 ENST00000320963.9
ENST00000394885.8
ENST00000394883.3
RCN2
reticulocalbin 2
chr21_+_6111123 0.44 ENST00000613488.3
SIK1B
salt inducible kinase 1B (putative)
chr16_+_3018390 0.43 ENST00000573001.5
TNFRSF12A
TNF receptor superfamily member 12A
chr8_-_28386073 0.43 ENST00000523095.5
ENST00000522795.1
ZNF395
zinc finger protein 395
chr14_-_87992838 0.42 ENST00000544807.6
GALC
galactosylceramidase
chr20_+_6767678 0.42 ENST00000378827.5
BMP2
bone morphogenetic protein 2
chr14_-_87993159 0.42 ENST00000393568.8
ENST00000261304.7
GALC
galactosylceramidase
chr2_-_86563470 0.41 ENST00000409225.2
CHMP3
charged multivesicular body protein 3
chr18_-_55321640 0.41 ENST00000637169.2
TCF4
transcription factor 4
chr8_-_6563238 0.41 ENST00000629816.3
ENST00000523120.2
ANGPT2
angiopoietin 2
chr11_+_128694052 0.40 ENST00000527786.7
ENST00000534087.3
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr6_-_75206044 0.40 ENST00000322507.13
COL12A1
collagen type XII alpha 1 chain
chr4_+_70704713 0.40 ENST00000417478.6
RUFY3
RUN and FYVE domain containing 3
chr9_-_120714457 0.39 ENST00000373930.4
MEGF9
multiple EGF like domains 9
chr8_-_6563409 0.39 ENST00000325203.9
ANGPT2
angiopoietin 2
chr1_+_64470120 0.38 ENST00000651257.2
CACHD1
cache domain containing 1
chr19_+_5681000 0.38 ENST00000581893.5
ENST00000411793.6
ENST00000301382.8
ENST00000581773.5
ENST00000339423.7
ENST00000423665.6
ENST00000583928.5
ENST00000342970.6
ENST00000422535.6
ENST00000581521.5
HSD11B1L
hydroxysteroid 11-beta dehydrogenase 1 like
chr19_-_17264718 0.37 ENST00000431146.6
ENST00000594190.5
USHBP1
USH1 protein network component harmonin binding protein 1
chr16_-_15643024 0.37 ENST00000540441.6
MARF1
meiosis regulator and mRNA stability factor 1
chr4_+_53377749 0.37 ENST00000507166.5
ENSG00000282278.1
novel FIP1L1-PDGFRA fusion protein
chr11_+_128693887 0.37 ENST00000281428.12
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr7_+_16753731 0.37 ENST00000262067.5
TSPAN13
tetraspanin 13
chr10_-_13348270 0.37 ENST00000378614.8
ENST00000327347.10
ENST00000545675.5
SEPHS1
selenophosphate synthetase 1
chrX_+_85244075 0.36 ENST00000276123.7
ZNF711
zinc finger protein 711
chr11_-_10808304 0.36 ENST00000532082.6
EIF4G2
eukaryotic translation initiation factor 4 gamma 2
chr3_-_52685794 0.36 ENST00000424867.1
ENST00000394830.7
ENST00000431678.5
ENST00000450271.5
PBRM1
polybromo 1
chr10_-_24952573 0.36 ENST00000376378.5
ENST00000376376.3
ENST00000320152.11
PRTFDC1
phosphoribosyl transferase domain containing 1
chr19_+_10602436 0.35 ENST00000590382.5
ENST00000407327.8
SLC44A2
solute carrier family 44 member 2
chr15_+_81000913 0.35 ENST00000267984.4
TLNRD1
talin rod domain containing 1
chr14_+_22281097 0.35 ENST00000390465.2
TRAV38-2DV8
T cell receptor alpha variable 38-2/delta variable 8
chr1_-_201154418 0.34 ENST00000435310.5
ENST00000485839.6
TMEM9
transmembrane protein 9
chr9_-_71768386 0.34 ENST00000377066.9
ENST00000377044.9
CEMIP2
cell migration inducing hyaluronidase 2
chrX_+_85243983 0.34 ENST00000674551.1
ZNF711
zinc finger protein 711
chr3_-_65597886 0.33 ENST00000460329.6
MAGI1
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr11_+_5488685 0.33 ENST00000322641.5
OR52D1
olfactory receptor family 52 subfamily D member 1
chr3_+_25428233 0.32 ENST00000437042.6
ENST00000330688.9
RARB
retinoic acid receptor beta
chr9_-_70869076 0.32 ENST00000677594.1
TRPM3
transient receptor potential cation channel subfamily M member 3
chr9_-_72364504 0.31 ENST00000237937.7
ENST00000343431.6
ENST00000376956.3
ZFAND5
zinc finger AN1-type containing 5
chrX_+_85244032 0.31 ENST00000373165.7
ZNF711
zinc finger protein 711
chr1_-_201154459 0.30 ENST00000414605.2
ENST00000367330.6
ENST00000367334.9
ENST00000367332.5
TMEM9
transmembrane protein 9
chr7_-_99408548 0.29 ENST00000626285.1
ENST00000350498.8
PDAP1
PDGFA associated protein 1
chr9_-_122227525 0.29 ENST00000373755.6
ENST00000373754.6
LHX6
LIM homeobox 6
chr2_+_10123171 0.29 ENST00000615152.5
RRM2
ribonucleotide reductase regulatory subunit M2
chr1_+_13585453 0.28 ENST00000487038.5
ENST00000475043.5
PDPN
podoplanin
chr3_+_183635605 0.28 ENST00000493074.1
ENST00000437402.5
ENST00000454495.6
ENST00000473045.5
ENST00000468101.5
ENST00000427201.2
ENST00000482138.1
ENST00000454652.6
ENST00000242810.11
KLHL24
kelch like family member 24
chr19_+_46602050 0.28 ENST00000599839.5
ENST00000596362.1
CALM3
calmodulin 3
chr11_-_82997394 0.27 ENST00000525117.5
ENST00000532548.5
RAB30
RAB30, member RAS oncogene family
chr11_-_82997477 0.27 ENST00000534301.5
RAB30
RAB30, member RAS oncogene family
chr18_-_55321986 0.27 ENST00000570287.6
TCF4
transcription factor 4
chr8_-_94896660 0.27 ENST00000520509.5
CCNE2
cyclin E2
chr6_+_125919296 0.27 ENST00000444128.2
NCOA7
nuclear receptor coactivator 7
chrX_+_81202066 0.27 ENST00000373212.6
SH3BGRL
SH3 domain binding glutamate rich protein like
chr19_-_17264732 0.27 ENST00000252597.8
USHBP1
USH1 protein network component harmonin binding protein 1
chr18_+_13218769 0.26 ENST00000677055.1
ENST00000399848.7
LDLRAD4
low density lipoprotein receptor class A domain containing 4
chr12_+_99647749 0.26 ENST00000324341.2
FAM71C
family with sequence similarity 71 member C
chrX_+_71283577 0.26 ENST00000420903.6
ENST00000373856.8
ENST00000678437.1
ENST00000678830.1
ENST00000677879.1
ENST00000373841.5
ENST00000276079.13
ENST00000676797.1
ENST00000678660.1
ENST00000678231.1
ENST00000677612.1
ENST00000413858.5
ENST00000450092.6
NONO
non-POU domain containing octamer binding
chr6_+_125919210 0.26 ENST00000438495.6
NCOA7
nuclear receptor coactivator 7
chr16_+_3654683 0.26 ENST00000246949.10
DNASE1
deoxyribonuclease 1
chr11_-_44950151 0.26 ENST00000533940.5
ENST00000533937.1
TP53I11
tumor protein p53 inducible protein 11
chr14_-_74875998 0.25 ENST00000556489.4
ENST00000673765.1
PROX2
prospero homeobox 2
chr5_-_180591488 0.25 ENST00000292641.4
SCGB3A1
secretoglobin family 3A member 1
chr15_-_72783611 0.25 ENST00000563907.5
ADPGK
ADP dependent glucokinase
chr7_-_128775793 0.25 ENST00000249389.3
OPN1SW
opsin 1, short wave sensitive
chr13_+_111115303 0.25 ENST00000646102.2
ENST00000449979.5
ARHGEF7
Rho guanine nucleotide exchange factor 7
chr6_+_32969345 0.24 ENST00000678250.1
BRD2
bromodomain containing 2
chr4_-_22443110 0.24 ENST00000508133.5
ADGRA3
adhesion G protein-coupled receptor A3
chr8_-_140800535 0.24 ENST00000521986.5
ENST00000523539.5
PTK2
protein tyrosine kinase 2
chr7_+_107583919 0.24 ENST00000491150.5
BCAP29
B cell receptor associated protein 29
chr4_-_137532452 0.24 ENST00000412923.6
ENST00000511115.5
ENST00000344876.9
ENST00000507846.5
ENST00000510305.5
ENST00000611581.1
PCDH18
protocadherin 18
chr4_+_26584064 0.24 ENST00000264866.9
ENST00000505206.5
ENST00000511789.5
TBC1D19
TBC1 domain family member 19
chr5_+_141172637 0.24 ENST00000231137.6
PCDHB7
protocadherin beta 7
chr1_-_156859087 0.24 ENST00000368195.4
INSRR
insulin receptor related receptor
chr9_+_88388356 0.24 ENST00000375859.4
SPIN1
spindlin 1
chr2_-_75560893 0.23 ENST00000410113.5
ENST00000393913.8
EVA1A
eva-1 homolog A, regulator of programmed cell death
chr1_+_15758768 0.23 ENST00000483633.6
ENST00000502739.5
ENST00000375766.8
ENST00000431771.6
FBLIM1
filamin binding LIM protein 1
chr3_+_152268920 0.23 ENST00000495875.6
ENST00000324210.10
ENST00000493459.5
MBNL1
muscleblind like splicing regulator 1
chr1_-_21176836 0.23 ENST00000634879.2
ENST00000400422.6
ENST00000602326.5
ENST00000411888.5
ENST00000438975.5
ENST00000374935.7
EIF4G3
eukaryotic translation initiation factor 4 gamma 3
chr17_-_42136431 0.22 ENST00000552162.5
ENST00000550504.5
RAB5C
RAB5C, member RAS oncogene family
chr11_+_114060204 0.22 ENST00000683318.1
ZBTB16
zinc finger and BTB domain containing 16
chrX_-_16712572 0.22 ENST00000359276.9
CTPS2
CTP synthase 2
chr11_-_44950867 0.22 ENST00000528290.5
ENST00000525680.6
ENST00000530035.5
ENST00000527685.5
TP53I11
tumor protein p53 inducible protein 11
chr6_+_32969165 0.22 ENST00000496118.2
ENST00000449085.4
BRD2
bromodomain containing 2
chr5_+_141350081 0.22 ENST00000523390.2
ENST00000611598.1
PCDHGB1
protocadherin gamma subfamily B, 1
chr14_-_34874887 0.22 ENST00000382422.6
BAZ1A
bromodomain adjacent to zinc finger domain 1A
chr2_-_70248598 0.22 ENST00000445587.5
ENST00000433529.7
ENST00000415783.6
TIA1
TIA1 cytotoxic granule associated RNA binding protein
chr21_-_39313578 0.21 ENST00000380800.7
BRWD1
bromodomain and WD repeat domain containing 1
chr1_+_33256479 0.21 ENST00000539719.6
ENST00000483388.5
ZNF362
zinc finger protein 362
chr11_-_44950839 0.21 ENST00000395648.7
ENST00000531928.6
TP53I11
tumor protein p53 inducible protein 11
chr22_-_38084093 0.21 ENST00000681075.1
SLC16A8
solute carrier family 16 member 8
chr2_+_61065863 0.21 ENST00000402291.6
KIAA1841
KIAA1841
chr11_+_46381033 0.21 ENST00000359803.7
MDK
midkine
chr2_-_86563382 0.21 ENST00000263856.9
CHMP3
charged multivesicular body protein 3
chr19_-_17460804 0.21 ENST00000594663.1
ENSG00000269035.1
novel protein
chr10_+_22316375 0.20 ENST00000376836.8
ENST00000456711.5
ENST00000444869.5
ENST00000475460.6
ENST00000602390.5
ENST00000489125.2
COMMD3
COMMD3-BMI1
COMM domain containing 3
COMMD3-BMI1 readthrough
chr7_+_80638633 0.20 ENST00000447544.7
ENST00000482059.6
CD36
CD36 molecule
chr17_-_78717018 0.20 ENST00000585509.5
CYTH1
cytohesin 1
chr8_+_11802667 0.20 ENST00000443614.6
ENST00000220584.9
ENST00000525900.5
FDFT1
farnesyl-diphosphate farnesyltransferase 1
chr11_+_73308237 0.20 ENST00000263674.4
ARHGEF17
Rho guanine nucleotide exchange factor 17
chr19_+_48469354 0.20 ENST00000452733.7
ENST00000641098.1
CYTH2
cytohesin 2
chr1_+_150067279 0.20 ENST00000643970.1
ENST00000535106.5
ENST00000369128.9
VPS45
vacuolar protein sorting 45 homolog
chr12_+_59664677 0.19 ENST00000548610.5
SLC16A7
solute carrier family 16 member 7
chr5_+_102808057 0.19 ENST00000684043.1
ENST00000682407.1
PAM
peptidylglycine alpha-amidating monooxygenase
chrX_-_40096190 0.19 ENST00000679513.1
BCOR
BCL6 corepressor
chr8_+_11802611 0.19 ENST00000623368.3
FDFT1
farnesyl-diphosphate farnesyltransferase 1
chr11_+_46381194 0.19 ENST00000533952.5
MDK
midkine
chr12_+_22625357 0.19 ENST00000545979.2
ETNK1
ethanolamine kinase 1
chr10_+_22316445 0.19 ENST00000448361.5
COMMD3
COMM domain containing 3
chr1_+_93448155 0.19 ENST00000370253.6
FNBP1L
formin binding protein 1 like
chr12_+_69585666 0.19 ENST00000543146.2
CCT2
chaperonin containing TCP1 subunit 2
chr22_+_38656627 0.19 ENST00000411557.5
ENST00000396811.6
ENST00000216029.7
ENST00000416285.5
CBY1
chibby family member 1, beta catenin antagonist
chr2_-_157325808 0.19 ENST00000410096.6
ENST00000420719.6
ENST00000409216.5
ENST00000419116.2
ERMN
ermin
chr5_-_157575767 0.19 ENST00000257527.9
ADAM19
ADAM metallopeptidase domain 19
chr10_+_21524627 0.18 ENST00000651097.1
MLLT10
MLLT10 histone lysine methyltransferase DOT1L cofactor
chr2_-_70248454 0.18 ENST00000416149.6
ENST00000282574.8
TIA1
TIA1 cytotoxic granule associated RNA binding protein
chr1_-_201507116 0.18 ENST00000340006.7
ENST00000526256.5
ENST00000526723.5
ENST00000524951.5
CSRP1
cysteine and glycine rich protein 1
chr11_-_95232514 0.18 ENST00000634898.1
ENST00000542176.1
ENST00000278499.6
SESN3
sestrin 3
chr17_+_77451244 0.18 ENST00000591088.5
SEPTIN9
septin 9
chr7_-_108003122 0.18 ENST00000393559.2
ENST00000222399.11
ENST00000676777.1
ENST00000439976.6
ENST00000393560.5
ENST00000677793.1
ENST00000679244.1
LAMB1
laminin subunit beta 1
chr2_+_69013379 0.18 ENST00000409349.7
ANTXR1
ANTXR cell adhesion molecule 1
chr16_+_2033264 0.18 ENST00000565855.5
ENST00000566198.1
SLC9A3R2
SLC9A3 regulator 2
chr14_-_34875348 0.17 ENST00000360310.6
BAZ1A
bromodomain adjacent to zinc finger domain 1A
chrX_+_130339886 0.17 ENST00000543953.5
ENST00000612248.4
ENST00000424447.5
ENST00000545805.6
SLC25A14
solute carrier family 25 member 14
chr15_+_51751587 0.17 ENST00000539962.6
ENST00000249700.9
TMOD2
tropomodulin 2
chr11_+_60924452 0.17 ENST00000453848.7
ENST00000544065.5
ENST00000005286.8
TMEM132A
transmembrane protein 132A
chr2_+_10122730 0.17 ENST00000304567.10
RRM2
ribonucleotide reductase regulatory subunit M2
chr21_+_37073213 0.16 ENST00000418766.5
ENST00000450533.5
ENST00000438055.5
ENST00000355666.5
ENST00000540756.5
ENST00000399010.5
TTC3
tetratricopeptide repeat domain 3
chr9_+_136980211 0.16 ENST00000444903.2
PTGDS
prostaglandin D2 synthase
chr14_+_23322019 0.16 ENST00000557702.5
PABPN1
poly(A) binding protein nuclear 1
chr3_+_136022734 0.15 ENST00000334546.6
PPP2R3A
protein phosphatase 2 regulatory subunit B''alpha
chr5_+_141177790 0.15 ENST00000239444.4
ENST00000623995.1
PCDHB8
ENSG00000279472.1
protocadherin beta 8
novel transcript
chr9_-_39239174 0.15 ENST00000358144.6
CNTNAP3
contactin associated protein family member 3
chr3_-_197298092 0.15 ENST00000392382.6
DLG1
discs large MAGUK scaffold protein 1
chr12_-_85836372 0.15 ENST00000361228.5
RASSF9
Ras association domain family member 9
chr12_+_50504970 0.15 ENST00000301180.10
DIP2B
disco interacting protein 2 homolog B
chr20_-_17531366 0.15 ENST00000377873.8
BFSP1
beaded filament structural protein 1
chr6_+_87344812 0.14 ENST00000388923.5
C6orf163
chromosome 6 open reading frame 163
chr3_+_133400046 0.14 ENST00000302334.3
BFSP2
beaded filament structural protein 2
chr12_+_22625182 0.14 ENST00000538218.2
ETNK1
ethanolamine kinase 1
chr7_+_77538059 0.14 ENST00000435495.6
PTPN12
protein tyrosine phosphatase non-receptor type 12
chr7_-_19773569 0.14 ENST00000422233.5
ENST00000433641.5
ENST00000405844.6
TMEM196
transmembrane protein 196
chr8_-_119673368 0.14 ENST00000427067.6
ENPP2
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr15_-_72783685 0.14 ENST00000456471.3
ENST00000311669.12
ADPGK
ADP dependent glucokinase
chr16_-_31073712 0.14 ENST00000414399.1
ZNF668
zinc finger protein 668
chrX_+_130339941 0.14 ENST00000218197.9
SLC25A14
solute carrier family 25 member 14
chr10_+_21524670 0.13 ENST00000631589.1
MLLT10
MLLT10 histone lysine methyltransferase DOT1L cofactor
chr4_+_53377630 0.13 ENST00000337488.11
ENST00000358575.9
ENST00000507922.5
ENST00000306932.10
FIP1L1
factor interacting with PAPOLA and CPSF1
chrX_-_2500555 0.13 ENST00000381218.8
ZBED1
zinc finger BED-type containing 1
chr11_-_62646598 0.13 ENST00000648273.1
ENST00000356638.8
ENST00000346178.8
ENST00000534779.5
ENST00000525994.1
ENST00000540933.5
GANAB
glucosidase II alpha subunit
chr8_-_33567118 0.13 ENST00000256257.2
RNF122
ring finger protein 122
chr16_-_1782526 0.12 ENST00000566339.6
SPSB3
splA/ryanodine receptor domain and SOCS box containing 3
chrX_+_146809768 0.12 ENST00000438525.3
CXorf51B
chromosome X open reading frame 51B
chr9_+_131228109 0.12 ENST00000498010.2
ENST00000476004.5
ENST00000528406.1
NUP214
nucleoporin 214
chr6_+_31815532 0.12 ENST00000375651.7
ENST00000608703.1
HSPA1A
heat shock protein family A (Hsp70) member 1A
chr20_-_35954461 0.12 ENST00000305978.7
SCAND1
SCAN domain containing 1
chr2_+_25042064 0.12 ENST00000403714.8
ENST00000401432.7
EFR3B
EFR3 homolog B
chr3_-_15521675 0.12 ENST00000383788.10
ENST00000383786.9
ENST00000603808.5
COLQ
collagen like tail subunit of asymmetric acetylcholinesterase

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0006683 galactosylceramide catabolic process(GO:0006683)
0.4 1.3 GO:0050928 negative regulation of positive chemotaxis(GO:0050928)
0.3 1.0 GO:1902809 regulation of skeletal muscle fiber differentiation(GO:1902809)
0.3 1.0 GO:0035026 leading edge cell differentiation(GO:0035026)
0.3 1.1 GO:0021571 rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.3 0.8 GO:0038162 erythropoietin-mediated signaling pathway(GO:0038162)
0.2 1.1 GO:1901202 negative regulation of extracellular matrix assembly(GO:1901202)
0.2 0.6 GO:0072709 cellular response to sorbitol(GO:0072709)
0.2 2.1 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.2 0.7 GO:0050904 diapedesis(GO:0050904) glomerular endothelium development(GO:0072011)
0.2 0.5 GO:1904719 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.2 0.6 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.1 0.4 GO:0051040 regulation of calcium-independent cell-cell adhesion(GO:0051040) corticotropin hormone secreting cell differentiation(GO:0060128)
0.1 2.0 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 0.4 GO:1901069 guanosine-containing compound catabolic process(GO:1901069)
0.1 1.1 GO:0014807 regulation of somitogenesis(GO:0014807)
0.1 1.4 GO:1904424 regulation of GTP binding(GO:1904424)
0.1 0.3 GO:1904328 regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
0.1 0.4 GO:0016259 selenocysteine metabolic process(GO:0016259)
0.1 0.2 GO:0071469 cellular response to alkaline pH(GO:0071469)
0.1 0.5 GO:0035549 positive regulation of interferon-beta secretion(GO:0035549)
0.1 2.9 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 0.4 GO:0006696 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.1 0.4 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.1 0.5 GO:0003185 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.1 0.7 GO:2000587 negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.1 0.4 GO:0030421 defecation(GO:0030421)
0.1 0.3 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.1 0.5 GO:0048539 bone marrow development(GO:0048539)
0.1 0.2 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.1 0.2 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.1 0.2 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.0 0.2 GO:0018032 protein amidation(GO:0018032)
0.0 0.2 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.0 0.4 GO:2000334 response to linoleic acid(GO:0070543) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.0 0.2 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.2 GO:0051138 positive regulation of NK T cell differentiation(GO:0051138)
0.0 0.3 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.0 0.6 GO:0051601 exocyst localization(GO:0051601)
0.0 0.1 GO:0042938 dipeptide transport(GO:0042938)
0.0 0.4 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.0 0.1 GO:0070434 positive regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070426) positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070434)
0.0 0.1 GO:0001507 acetylcholine catabolic process in synaptic cleft(GO:0001507) acetylcholine catabolic process(GO:0006581)
0.0 0.3 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.3 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.4 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.0 0.1 GO:0009597 detection of virus(GO:0009597)
0.0 0.8 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.2 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.0 0.6 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.3 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.2 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.0 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
0.0 0.2 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.4 GO:0015871 choline transport(GO:0015871)
0.0 0.1 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0 0.3 GO:0021853 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 0.1 GO:0052314 phytoalexin metabolic process(GO:0052314)
0.0 0.1 GO:2001045 closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 0.0 GO:0003290 atrial septum secundum morphogenesis(GO:0003290)
0.0 0.6 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.0 0.1 GO:0034239 macrophage fusion(GO:0034238) regulation of macrophage fusion(GO:0034239) positive regulation of macrophage fusion(GO:0034241)
0.0 0.2 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 5.8 GO:0031032 actomyosin structure organization(GO:0031032)
0.0 0.3 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.1 GO:2000394 positive regulation of lamellipodium morphogenesis(GO:2000394)
0.0 0.1 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.0 0.5 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.0 0.1 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.4 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.1 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.2 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.2 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.0 0.1 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.0 0.3 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.1 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.1 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 0.4 GO:0008623 CHRAC(GO:0008623)
0.1 0.9 GO:0097165 nuclear stress granule(GO:0097165)
0.1 0.4 GO:0005595 collagen type XII trimer(GO:0005595)
0.1 0.5 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.1 0.3 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
0.1 0.2 GO:0005606 laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259)
0.0 2.0 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.6 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.1 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.0 0.5 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 1.1 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.7 GO:0005922 connexon complex(GO:0005922)
0.0 0.9 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.2 GO:0000322 storage vacuole(GO:0000322)
0.0 0.8 GO:0042629 mast cell granule(GO:0042629)
0.0 0.1 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 0.6 GO:0000145 exocyst(GO:0000145)
0.0 0.9 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.3 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 1.1 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.4 GO:0071437 invadopodium(GO:0071437)
0.0 0.2 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.2 GO:0061700 GATOR2 complex(GO:0061700)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0004336 galactosylceramidase activity(GO:0004336)
0.2 0.5 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116)
0.1 0.5 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1 2.6 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.7 GO:1903763 gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.1 0.4 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.1 0.2 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.1 0.4 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.1 0.2 GO:0001069 regulatory region RNA binding(GO:0001069)
0.1 0.2 GO:0003883 CTP synthase activity(GO:0003883)
0.1 0.4 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.1 0.3 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.1 0.7 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.2 GO:0004598 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.0 0.8 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 1.0 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.2 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.0 0.4 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.1 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.0 0.1 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.0 0.7 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.4 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.6 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.0 0.5 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.1 GO:0016503 pheromone receptor activity(GO:0016503)
0.0 0.5 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.3 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.2 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.1 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.0 0.3 GO:0008517 folic acid transporter activity(GO:0008517)
0.0 0.3 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.1 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.0 0.3 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.6 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 1.4 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 0.0 GO:1904713 beta-catenin destruction complex binding(GO:1904713)
0.0 2.2 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.0 0.5 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.0 GO:0004796 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.0 0.2 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.0 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 0.0 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.0 1.1 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.1 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 0.4 GO:0008143 poly(A) binding(GO:0008143)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 1.1 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 1.4 PID ARF6 PATHWAY Arf6 signaling events
0.0 2.3 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.3 PID FOXO PATHWAY FoxO family signaling
0.0 1.5 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.6 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 0.9 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.2 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.5 PID TNF PATHWAY TNF receptor signaling pathway
0.0 1.0 PID TGFBR PATHWAY TGF-beta receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.3 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.6 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.7 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 1.2 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.7 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.5 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 2.3 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 1.1 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 1.7 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 1.4 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.6 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.3 REACTOME OPSINS Genes involved in Opsins
0.0 0.4 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.6 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.4 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.3 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation