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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for SOX8

Z-value: 0.81

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Transcription factors associated with SOX8

Gene Symbol Gene ID Gene Info
ENSG00000005513.10 SOX8

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX8hg38_v1_chr16_+_981762_9817820.193.6e-01Click!

Activity profile of SOX8 motif

Sorted Z-values of SOX8 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX8

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr10_+_102226293 1.48 ENST00000370005.4
ELOVL fatty acid elongase 3
chr14_+_75278820 1.10 ENST00000554617.1
ENST00000554212.5
ENST00000535987.5
ENST00000303562.9
ENST00000555242.1
Fos proto-oncogene, AP-1 transcription factor subunit
chr17_+_35760881 1.08 ENST00000605587.2
ENST00000604830.1
chromosome 17 open reading frame 50
chr10_+_86654541 1.01 ENST00000241891.10
ENST00000372071.6
opsin 4
chr6_+_116511626 1.00 ENST00000368599.4
calcium homeostasis modulator family member 5
chr5_-_22853320 0.90 ENST00000504376.6
ENST00000382254.6
cadherin 12
chr1_+_18630839 0.89 ENST00000420770.7
paired box 7
chrX_-_19965142 0.88 ENST00000340625.3
BCLAF1 and THRAP3 family member 3
chr14_-_106025628 0.81 ENST00000631943.1
immunoglobulin heavy variable 7-4-1
chr2_+_200440649 0.75 ENST00000366118.2
spermatogenesis associated serine rich 2 like
chr2_-_150487658 0.72 ENST00000375734.6
ENST00000263895.9
ENST00000454202.5
Rho family GTPase 3
chr8_+_12108172 0.65 ENST00000400078.3
zinc finger protein 705D
chr5_-_90474765 0.65 ENST00000316610.7
metallo-beta-lactamase domain containing 2
chr7_+_80646305 0.64 ENST00000426978.5
ENST00000432207.5
CD36 molecule
chr7_-_27152561 0.64 ENST00000467897.2
ENST00000612286.5
ENST00000498652.1
novel transcript
homeobox A3
novel transcript
chr8_-_141367276 0.64 ENST00000377741.4
G protein-coupled receptor 20
chr3_-_58211212 0.62 ENST00000461914.7
deoxyribonuclease 1 like 3
chr14_+_22105305 0.61 ENST00000390453.1
T cell receptor alpha variable 24
chr8_-_94208548 0.59 ENST00000027335.8
ENST00000441892.6
ENST00000521491.1
cadherin 17
chr13_-_48413105 0.57 ENST00000620633.5
lysophosphatidic acid receptor 6
chr9_-_21305313 0.55 ENST00000610521.2
interferon alpha 5
chr4_+_40191037 0.55 ENST00000505618.5
ras homolog family member H
chr5_-_160852200 0.52 ENST00000327245.10
ATPase phospholipid transporting 10B (putative)
chr12_-_9999176 0.52 ENST00000298527.10
ENST00000348658.4
C-type lectin domain family 1 member B
chr20_+_33562306 0.52 ENST00000344201.7
CBFA2/RUNX1 partner transcriptional co-repressor 2
chr19_-_37172670 0.52 ENST00000588354.1
ENST00000292841.10
ENST00000356958.8
zinc finger protein 585A
chr4_-_16083695 0.50 ENST00000510224.5
prominin 1
chr4_-_16083714 0.50 ENST00000508167.5
prominin 1
chr3_-_179071742 0.48 ENST00000311417.7
ENST00000652290.1
zinc finger matrin-type 3
chr11_+_10456186 0.47 ENST00000528723.5
adenosine monophosphate deaminase 3
chr14_-_106185387 0.45 ENST00000390605.2
immunoglobulin heavy variable 1-18
chr6_+_32637396 0.44 ENST00000395363.5
ENST00000496318.5
ENST00000343139.11
major histocompatibility complex, class II, DQ alpha 1
chr1_+_230979064 0.44 ENST00000366658.6
ENST00000310256.7
ENST00000450711.5
ENST00000435927.5
ARV1 homolog, fatty acid homeostasis modulator
chr4_-_16084002 0.43 ENST00000447510.7
prominin 1
chr3_-_52056552 0.43 ENST00000495880.2
dual specificity phosphatase 7
chr15_-_50265666 0.43 ENST00000543581.5
ENST00000267845.8
histidine decarboxylase
chr2_+_96325294 0.43 ENST00000439118.3
ENST00000420176.5
ENST00000536814.1
ITPRIP like 1
chr6_+_32637419 0.41 ENST00000374949.2
major histocompatibility complex, class II, DQ alpha 1
chr14_+_22040576 0.40 ENST00000390448.3
T cell receptor alpha variable 20
chr16_+_82035245 0.40 ENST00000199936.9
hydroxysteroid 17-beta dehydrogenase 2
chr7_+_80646436 0.40 ENST00000419819.2
CD36 molecule
chr3_-_54928044 0.39 ENST00000273286.6
leucine rich repeats and transmembrane domains 1
chr3_-_193554799 0.39 ENST00000295548.3
ATPase 13A4
chr2_-_166128004 0.38 ENST00000303395.9
ENST00000674923.1
ENST00000637988.1
ENST00000635776.1
sodium voltage-gated channel alpha subunit 1
chr3_+_98168700 0.37 ENST00000383696.4
olfactory receptor family 5 subfamily H member 15
chr19_-_37172432 0.37 ENST00000392157.2
zinc finger protein 585A
chr10_-_6062290 0.37 ENST00000256876.10
ENST00000379954.5
interleukin 2 receptor subunit alpha
chr7_+_64666156 0.36 ENST00000344930.7
zinc finger protein 107
chrX_+_15749848 0.36 ENST00000479740.5
ENST00000454127.2
carbonic anhydrase 5B
chr8_-_134510182 0.35 ENST00000521673.5
zinc finger and AT-hook domain containing
chr2_+_169694434 0.35 ENST00000616481.4
ENST00000616524.4
ENST00000617738.4
ENST00000359744.8
ENST00000438838.5
ENST00000438710.5
ENST00000449906.5
ENST00000498202.6
ENST00000272797.8
phosphatase, orphan 2
kelch like family member 23
chr5_+_95731300 0.34 ENST00000379982.8
Rho related BTB domain containing 3
chrX_-_133753681 0.34 ENST00000406757.2
glypican 3
chr17_-_49646581 0.33 ENST00000510476.5
ENST00000503676.5
speckle type BTB/POZ protein
chr17_+_1742836 0.33 ENST00000324015.7
ENST00000450523.6
ENST00000453723.5
ENST00000453066.6
ENST00000382061.5
serpin family F member 2
chr14_-_106005574 0.33 ENST00000390595.3
immunoglobulin heavy variable 1-3
chr12_+_55549602 0.32 ENST00000641569.1
ENST00000641851.1
olfactory receptor family 6 subfamily C member 4
chr4_+_73481737 0.31 ENST00000226355.5
afamin
chr10_-_37976589 0.31 ENST00000302609.8
zinc finger protein 25
chr9_-_14322320 0.31 ENST00000606230.2
nuclear factor I B
chr12_-_119804298 0.30 ENST00000678652.1
ENST00000678494.1
citron rho-interacting serine/threonine kinase
chr4_-_21697755 0.30 ENST00000382148.7
potassium voltage-gated channel interacting protein 4
chr16_+_87951424 0.30 ENST00000439677.5
ENST00000286122.11
ENST00000454563.5
ENST00000479780.6
ENST00000682872.1
ENST00000393208.6
ENST00000412691.5
ENST00000626016.2
ENST00000355022.8
BTG3 associated nuclear protein
chr17_+_63998344 0.30 ENST00000577953.5
ENST00000582540.5
ENST00000579184.5
ENST00000425164.7
ENST00000412177.6
ENST00000583891.5
ENST00000580752.1
proline rich 29
chr7_+_64794388 0.30 ENST00000359735.7
zinc finger protein 138
chr2_+_26401909 0.30 ENST00000288710.7
dynein regulatory complex subunit 1
chr7_-_120858303 0.30 ENST00000415871.5
ENST00000430985.1
tetraspanin 12
chr3_+_138347648 0.30 ENST00000614350.4
ENST00000289104.8
muscle RAS oncogene homolog
chr7_+_124476371 0.30 ENST00000473520.1
SSU72 pseudogene 8
chr1_+_67307360 0.30 ENST00000262345.5
ENST00000544434.5
interleukin 12 receptor subunit beta 2
chr3_-_58210961 0.29 ENST00000486455.5
ENST00000394549.7
deoxyribonuclease 1 like 3
chr19_-_49036885 0.29 ENST00000604577.1
ENST00000591656.1
ENST00000301407.8
ENST00000601167.1
novel protein
chorionic gonadotropin subunit beta 1
chr5_+_77030360 0.29 ENST00000312916.12
ENST00000506806.1
angiogenic factor with G-patch and FHA domains 1
chr19_+_23117018 0.29 ENST00000597761.7
zinc finger protein 730
chr4_-_149815826 0.28 ENST00000636793.2
ENST00000636414.1
IQ motif containing M
chr17_-_68955332 0.28 ENST00000269080.6
ENST00000615593.4
ENST00000586539.6
ENST00000430352.6
ATP binding cassette subfamily A member 8
chr5_+_148394712 0.28 ENST00000513826.1
F-box protein 38
chr1_+_15617415 0.28 ENST00000480945.6
DNA damage inducible 1 homolog 2
chr7_-_13986498 0.27 ENST00000420159.6
ENST00000399357.7
ENST00000403527.5
ETS variant transcription factor 1
chr18_-_31684504 0.27 ENST00000383131.3
ENST00000237019.11
ENST00000306851.10
beta-1,4-galactosyltransferase 6
chr7_-_64563032 0.27 ENST00000447137.2
zinc finger protein 680
chr1_-_12831410 0.26 ENST00000619922.1
PRAME family member 11
chr10_-_48274567 0.26 ENST00000636244.1
ENST00000374201.8
FERM and PDZ domain containing 2
chr17_+_42980547 0.26 ENST00000361677.5
ENST00000589705.1
RUN domain containing 1
chr12_-_10826358 0.26 ENST00000240619.2
taste 2 receptor member 10
chr2_+_232662733 0.26 ENST00000410095.5
ENST00000611312.1
EF-hand domain family member D1
chr10_-_126670686 0.25 ENST00000488181.3
chromosome 10 open reading frame 90
chr16_+_53207981 0.25 ENST00000565803.2
chromodomain helicase DNA binding protein 9
chr3_-_108953870 0.25 ENST00000261047.8
guanylate cyclase activator 1C
chr14_-_21094488 0.25 ENST00000555270.5
zinc finger protein 219
chr3_-_179072205 0.25 ENST00000432729.5
zinc finger matrin-type 3
chr18_-_28036585 0.25 ENST00000399380.7
cadherin 2
chr5_+_90474848 0.24 ENST00000651687.1
RNA polymerase III subunit G
chr7_-_38249572 0.24 ENST00000436911.6
T cell receptor gamma constant 2
chr1_-_34929574 0.24 ENST00000373347.6
DLG associated protein 3
chr12_-_119803383 0.24 ENST00000392520.2
ENST00000678677.1
ENST00000679249.1
ENST00000676849.1
citron rho-interacting serine/threonine kinase
chr5_+_90474879 0.24 ENST00000504930.5
ENST00000514483.5
RNA polymerase III subunit G
chr8_-_90082871 0.24 ENST00000265431.7
calbindin 1
chr7_+_91940970 0.24 ENST00000359028.7
A-kinase anchoring protein 9
chr18_-_49849827 0.24 ENST00000592688.1
myosin VB
chr12_-_122703346 0.24 ENST00000328880.6
hydroxycarboxylic acid receptor 2
chr15_+_72118392 0.23 ENST00000340912.6
SUMO peptidase family member, NEDD8 specific
chr5_+_140806929 0.23 ENST00000378125.4
ENST00000618834.1
ENST00000530339.2
ENST00000512229.6
ENST00000672575.1
protocadherin alpha 4
chr2_-_152098810 0.23 ENST00000636442.1
ENST00000638005.1
calcium voltage-gated channel auxiliary subunit beta 4
chr2_+_189857393 0.23 ENST00000452382.1
PMS1 homolog 1, mismatch repair system component
chr3_+_156291020 0.23 ENST00000302490.12
potassium voltage-gated channel subfamily A member regulatory beta subunit 1
chrX_-_54798253 0.23 ENST00000218436.7
inter-alpha-trypsin inhibitor heavy chain family member 6
chr3_+_142623386 0.22 ENST00000337777.7
ENST00000497199.5
plastin 1
chr9_-_123184233 0.22 ENST00000447404.6
spermatid perinuclear RNA binding protein
chr8_+_119067239 0.21 ENST00000332843.3
collectin subfamily member 10
chr3_-_165837412 0.21 ENST00000479451.5
ENST00000488954.1
ENST00000264381.8
butyrylcholinesterase
chr12_+_112418889 0.21 ENST00000392597.5
protein tyrosine phosphatase non-receptor type 11
chr1_+_111473972 0.21 ENST00000369718.4
chromosome 1 open reading frame 162
chr1_+_70411241 0.21 ENST00000370938.8
ENST00000346806.2
cystathionine gamma-lyase
chr5_+_178859924 0.21 ENST00000322434.8
zinc finger protein 354B
chr16_+_67570741 0.21 ENST00000644753.1
ENST00000642819.1
ENST00000645306.1
CCCTC-binding factor
chr4_-_99435336 0.21 ENST00000437033.7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr11_+_124184244 0.20 ENST00000641546.1
olfactory receptor family 10 subfamily D member 3
chr8_+_2045037 0.20 ENST00000262113.9
myomesin 2
chr19_+_51225059 0.20 ENST00000436584.6
ENST00000421133.6
ENST00000262262.5
ENST00000391796.7
CD33 molecule
chr22_-_23632317 0.20 ENST00000317749.9
aspartate rich 1
chr11_-_18939493 0.20 ENST00000526914.1
MAS related GPR family member X1
chr2_+_102473219 0.20 ENST00000295269.5
solute carrier family 9 member A4
chr3_+_98497681 0.20 ENST00000427338.3
olfactory receptor family 5 subfamily K member 2
chr1_-_201023694 0.20 ENST00000332129.6
ENST00000422435.2
ENST00000461742.7
kinesin family member 21B
chr14_-_106875069 0.19 ENST00000390639.2
immunoglobulin heavy variable 7-81 (non-functional)
chr11_+_67452392 0.19 ENST00000438189.6
calcium binding protein 4
chr4_-_99435396 0.19 ENST00000209665.8
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr15_-_65611110 0.19 ENST00000567744.5
ENST00000568573.1
ENST00000562830.1
ENST00000569491.5
ENST00000561769.1
integrator complex subunit 14
chr6_-_132757883 0.19 ENST00000525289.5
ENST00000326499.11
vanin 2
chr5_+_55160161 0.19 ENST00000296734.6
ENST00000515370.1
ENST00000503787.6
glutathione peroxidase 8 (putative)
chr14_+_22479521 0.19 ENST00000390483.1
T cell receptor alpha joining 56
chr8_+_2045058 0.19 ENST00000523438.1
myomesin 2
chr16_+_57358775 0.18 ENST00000219235.5
C-C motif chemokine ligand 22
chr4_+_95051671 0.18 ENST00000440890.7
bone morphogenetic protein receptor type 1B
chr2_+_85584402 0.18 ENST00000306384.5
vesicle associated membrane protein 5
chr9_-_127771335 0.18 ENST00000373276.7
ENST00000373277.8
SH2 domain containing 3C
chr14_-_106593319 0.18 ENST00000390627.3
immunoglobulin heavy variable 3-53
chr19_+_51573171 0.18 ENST00000436511.2
zinc finger protein 175
chr17_-_45262084 0.18 ENST00000331780.5
spermatogenesis associated 32
chr6_+_27810041 0.18 ENST00000369163.3
H3 clustered histone 10
chr17_-_8118489 0.17 ENST00000380149.6
ENST00000448843.7
arachidonate lipoxygenase 3
chr4_-_87529359 0.17 ENST00000458304.2
ENST00000282470.11
SPARC like 1
chr14_+_55661272 0.17 ENST00000555573.5
kinectin 1
chr8_+_106726012 0.17 ENST00000449762.6
ENST00000297447.10
oxidation resistance 1
chr6_+_26183750 0.17 ENST00000614097.3
H2B clustered histone 6
chr3_-_49422429 0.17 ENST00000637682.1
ENST00000427987.6
ENST00000636199.1
ENST00000638063.1
ENST00000636865.1
ENST00000458307.6
ENST00000273588.9
ENST00000635808.1
ENST00000636522.1
ENST00000636597.1
ENST00000538581.6
ENST00000395338.7
ENST00000462048.2
aminomethyltransferase
chrX_+_2828808 0.16 ENST00000381163.7
glycogenin 2
chr12_-_10130143 0.16 ENST00000298523.9
ENST00000396484.6
ENST00000310002.4
ENST00000304084.13
C-type lectin domain containing 7A
chr14_+_94612383 0.16 ENST00000393080.8
ENST00000555820.1
ENST00000393078.5
ENST00000467132.5
serpin family A member 3
chr18_+_34593392 0.16 ENST00000684377.1
dystrobrevin alpha
chr7_-_122098831 0.16 ENST00000681213.1
ENST00000679419.1
aminoadipate-semialdehyde synthase
chr3_+_148865288 0.16 ENST00000296046.4
carboxypeptidase A3
chr18_-_27990256 0.16 ENST00000675173.1
cadherin 2
chr19_+_21397156 0.16 ENST00000339914.6
ENST00000599461.1
zinc finger protein 493
chr6_-_41736239 0.16 ENST00000358871.6
transcription factor EB
chr12_-_10130241 0.16 ENST00000353231.9
ENST00000525605.1
C-type lectin domain containing 7A
chr2_-_158380960 0.16 ENST00000409187.5
coiled-coil domain containing 148
chr16_+_8712943 0.16 ENST00000561870.5
ENST00000396600.6
4-aminobutyrate aminotransferase
chr2_-_182242031 0.16 ENST00000358139.6
phosphodiesterase 1A
chr12_-_101830671 0.16 ENST00000549165.1
N-acetylglucosamine-1-phosphate transferase subunits alpha and beta
chr1_+_95151377 0.15 ENST00000604203.1
TLCD4-RWDD3 readthrough
chr12_-_16600703 0.15 ENST00000616247.4
LIM domain only 3
chr11_+_7987314 0.15 ENST00000531572.2
ENST00000651655.1
eukaryotic translation initiation factor 3 subunit F
chr17_-_7484205 0.15 ENST00000311403.4
zinc finger and BTB domain containing 4
chr16_+_30375820 0.15 ENST00000566955.1
myosin light chain, phosphorylatable, fast skeletal muscle
chr9_-_69014090 0.15 ENST00000377276.5
protein kinase cAMP-activated catalytic subunit gamma
chr10_-_50279715 0.15 ENST00000395526.9
N-acylsphingosine amidohydrolase 2
chr6_-_31721679 0.15 ENST00000495859.1
ENST00000375819.3
lymphocyte antigen 6 family member G6C
chr20_+_33662310 0.15 ENST00000375222.4
chromosome 20 open reading frame 144
chr7_+_139778229 0.14 ENST00000425687.5
ENST00000650822.1
ENST00000416849.6
ENST00000438104.6
ENST00000336425.10
thromboxane A synthase 1
chr4_-_86101922 0.14 ENST00000472236.5
ENST00000641881.1
mitogen-activated protein kinase 10
chr6_-_75363003 0.14 ENST00000370020.1
filamin A interacting protein 1
chr1_+_26169891 0.14 ENST00000374266.7
ENST00000270812.6
zinc finger protein 593
chr1_+_248509536 0.14 ENST00000641501.1
olfactory receptor family 2 subfamily G member 6
chr6_+_31739948 0.14 ENST00000375755.8
ENST00000425703.5
ENST00000375750.9
ENST00000375703.7
ENST00000375740.7
mutS homolog 5
chr17_-_35880350 0.14 ENST00000605140.6
ENST00000651122.1
ENST00000603197.6
C-C motif chemokine ligand 5
chr1_-_31764333 0.14 ENST00000398542.5
ENST00000373658.8
adhesion G protein-coupled receptor B2
chr3_+_156290982 0.14 ENST00000618897.4
potassium voltage-gated channel subfamily A member regulatory beta subunit 1
chr3_+_97439603 0.14 ENST00000514100.5
EPH receptor A6
chr9_+_81928428 0.13 ENST00000419782.5
SPATA31 subfamily D member 4
chr2_+_101998955 0.13 ENST00000393414.6
interleukin 1 receptor type 2
chr3_+_98463201 0.13 ENST00000642057.1
olfactory receptor family 5 subfamily K member 1
chr11_+_9461003 0.13 ENST00000438144.6
ENST00000396602.7
ENST00000526657.5
ENST00000299606.6
ENST00000534265.5
ENST00000412390.6
zinc finger protein 143
chr6_-_109690500 0.13 ENST00000448084.6
adenylate kinase 9
chr1_+_111473792 0.13 ENST00000343534.9
chromosome 1 open reading frame 162
chr7_-_32490361 0.13 ENST00000410044.5
ENST00000450169.7
ENST00000409987.5
ENST00000409782.5
LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated
chr1_-_58546693 0.13 ENST00000456980.5
ENST00000482274.2
ENST00000453710.1
ENST00000371226.8
ENST00000419242.5
ENST00000426139.5
OMA1 zinc metallopeptidase
chr9_+_124862098 0.13 ENST00000353214.6
actin related protein 2/3 complex subunit 5 like
chr6_-_109690515 0.12 ENST00000532976.1
adenylate kinase 9
chr11_-_4339244 0.12 ENST00000524542.2
SSU72 pseudogene 7
chr4_+_6693870 0.12 ENST00000296370.4
S100 calcium binding protein P
chr6_-_116829037 0.12 ENST00000368549.7
ENST00000530250.1
ENST00000310357.8
G protein-coupled receptor class C group 6 member A
chr1_-_153057504 0.12 ENST00000392653.3
small proline rich protein 2A
chr3_+_98166696 0.12 ENST00000641450.1
olfactory receptor family 5 subfamily H member 15
chr10_+_49988318 0.12 ENST00000374056.10
ENST00000679810.1
ArfGAP with GTPase domain, ankyrin repeat and PH domain 6
chr9_-_111038425 0.12 ENST00000441240.1
ENST00000683809.1
lysophosphatidic acid receptor 1
chr1_+_158931539 0.12 ENST00000368140.6
ENST00000368138.7
ENST00000392254.6
ENST00000392252.7
ENST00000368135.4
pyrin and HIN domain family member 1
chr1_+_203765168 0.11 ENST00000367217.5
ENST00000442561.7
lymphocyte transmembrane adaptor 1
chr8_+_38901218 0.11 ENST00000521746.5
ENST00000616927.4
pleckstrin homology domain containing A2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0014813 skeletal muscle satellite cell commitment(GO:0014813)
0.2 1.4 GO:2000768 positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
0.2 0.6 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.1 1.5 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.5 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.1 1.1 GO:0001661 conditioned taste aversion(GO:0001661)
0.1 1.0 GO:2000332 response to linoleic acid(GO:0070543) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.1 0.6 GO:0021615 specification of organ position(GO:0010159) glossopharyngeal nerve morphogenesis(GO:0021615)
0.1 0.3 GO:0072138 mesenchymal cell proliferation involved in ureteric bud development(GO:0072138)
0.1 0.3 GO:0061571 dADP phosphorylation(GO:0006174) dGDP phosphorylation(GO:0006186) AMP phosphorylation(GO:0006756) CDP phosphorylation(GO:0061508) dAMP phosphorylation(GO:0061565) CMP phosphorylation(GO:0061566) dCMP phosphorylation(GO:0061567) GDP phosphorylation(GO:0061568) UDP phosphorylation(GO:0061569) dCDP phosphorylation(GO:0061570) TDP phosphorylation(GO:0061571)
0.1 0.5 GO:0006196 AMP catabolic process(GO:0006196)
0.1 0.4 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.1 0.4 GO:0001692 histamine metabolic process(GO:0001692)
0.1 0.2 GO:0014016 neuroblast differentiation(GO:0014016)
0.1 0.4 GO:0032377 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.1 1.1 GO:0018298 protein-chromophore linkage(GO:0018298)
0.1 0.2 GO:2000850 negative regulation of cortisol secretion(GO:0051463) negative regulation of steroid hormone secretion(GO:2000832) negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850)
0.1 0.3 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.1 0.2 GO:0009085 lysine biosynthetic process(GO:0009085) lysine biosynthetic process via aminoadipic acid(GO:0019878)
0.0 0.4 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.0 0.4 GO:0003072 regulation of blood vessel size by renin-angiotensin(GO:0002034) renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure(GO:0003072)
0.0 0.2 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.0 0.4 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.0 0.2 GO:1902896 terminal web assembly(GO:1902896)
0.0 0.9 GO:0010623 programmed cell death involved in cell development(GO:0010623)
0.0 0.2 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.0 0.2 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.0 0.2 GO:0040030 regulation of molecular function, epigenetic(GO:0040030)
0.0 0.2 GO:0014053 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450)
0.0 0.2 GO:0032439 endosome localization(GO:0032439)
0.0 0.2 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0 0.1 GO:0050712 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.0 0.2 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.1 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.0 0.2 GO:0035502 metanephric part of ureteric bud development(GO:0035502)
0.0 0.2 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.3 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.1 GO:0099543 retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543)
0.0 1.2 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.2 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) negative regulation of chondrocyte proliferation(GO:1902731)
0.0 0.4 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.1 GO:0060545 regulation of nucleoside transport(GO:0032242) positive regulation of necroptotic process(GO:0060545)
0.0 0.4 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.1 GO:0006175 adenosine salvage(GO:0006169) dATP biosynthetic process(GO:0006175) purine deoxyribonucleoside triphosphate biosynthetic process(GO:0009216) adenosine biosynthetic process(GO:0046086)
0.0 0.1 GO:0036111 very long-chain fatty-acyl-CoA metabolic process(GO:0036111)
0.0 0.1 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.0 0.1 GO:0010536 positive regulation of activation of Janus kinase activity(GO:0010536) positive regulation of natural killer cell chemotaxis(GO:2000503)
0.0 0.2 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 0.6 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 0.4 GO:0060539 diaphragm development(GO:0060539)
0.0 1.2 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.5 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.2 GO:0051121 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.3 GO:0042908 xenobiotic transport(GO:0042908)
0.0 0.1 GO:1900133 regulation of renin secretion into blood stream(GO:1900133)
0.0 0.4 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.0 0.1 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.0 0.1 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.0 0.2 GO:0051661 maintenance of centrosome location(GO:0051661)
0.0 0.5 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.3 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.0 0.2 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.2 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.1 GO:0051026 chiasma assembly(GO:0051026)
0.0 0.1 GO:0000711 meiotic DNA repair synthesis(GO:0000711)
0.0 0.1 GO:1902044 regulation of Fas signaling pathway(GO:1902044)
0.0 0.1 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.1 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.0 0.6 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.1 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.0 0.5 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.5 GO:0030220 platelet formation(GO:0030220)
0.0 0.3 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.1 GO:0060371 regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371)
0.0 0.2 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.1 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.5 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.1 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
0.0 0.1 GO:0032485 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 GO:0035976 AP1 complex(GO:0035976)
0.1 1.3 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 0.2 GO:0044307 dendritic branch(GO:0044307)
0.0 0.4 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.9 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.4 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 1.3 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.2 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.0 0.2 GO:1990357 terminal web(GO:1990357)
0.0 0.3 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.1 GO:0097224 sperm connecting piece(GO:0097224)
0.0 1.0 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.2 GO:0032389 MutLalpha complex(GO:0032389)
0.0 0.5 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.4 GO:0016342 catenin complex(GO:0016342)
0.0 0.8 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.2 GO:0045179 apical cortex(GO:0045179)
0.0 0.1 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.1 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.0 0.5 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.2 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.1 GO:0031673 H zone(GO:0031673)
0.0 0.2 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.2 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.4 GO:0032982 myosin filament(GO:0032982)
0.0 0.1 GO:0032300 mismatch repair complex(GO:0032300)
0.0 0.3 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.2 GO:0005641 nuclear envelope lumen(GO:0005641)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0005502 11-cis retinal binding(GO:0005502)
0.1 1.5 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.4 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.1 1.0 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.1 0.5 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.1 0.6 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.1 0.3 GO:0060422 peptidyl-dipeptidase inhibitor activity(GO:0060422)
0.1 0.3 GO:0008431 vitamin E binding(GO:0008431)
0.1 0.4 GO:0004911 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.1 0.2 GO:0043035 chromatin insulator sequence binding(GO:0043035)
0.1 0.9 GO:0032395 MHC class II receptor activity(GO:0032395)
0.1 0.7 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 0.2 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.1 0.2 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
0.1 0.2 GO:0003990 acetylcholinesterase activity(GO:0003990) choline binding(GO:0033265)
0.1 0.5 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.1 GO:0036134 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.0 0.2 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.1 GO:0000035 acyl binding(GO:0000035)
0.0 0.2 GO:0032145 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.0 0.6 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.2 GO:0051120 hepoxilin A3 synthase activity(GO:0051120)
0.0 0.2 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.2 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 0.3 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.3 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.2 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.1 GO:0030298 receptor signaling protein tyrosine kinase activator activity(GO:0030298) CCR1 chemokine receptor binding(GO:0031726)
0.0 0.1 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.0 0.2 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.3 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.0 0.4 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.2 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.1 GO:0004001 adenosine kinase activity(GO:0004001)
0.0 0.1 GO:0044594 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594)
0.0 2.0 GO:0042805 actinin binding(GO:0042805)
0.0 0.6 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.7 GO:0005549 odorant binding(GO:0005549)
0.0 0.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.3 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
0.0 0.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.5 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.1 GO:0017098 sulfonylurea receptor binding(GO:0017098)
0.0 0.9 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.4 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)
0.0 1.1 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.2 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.4 GO:0038187 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 0.1 GO:0019862 IgA binding(GO:0019862)
0.0 0.8 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.4 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.4 GO:0070402 NADPH binding(GO:0070402)
0.0 0.5 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.1 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.2 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.5 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.4 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.1 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0 0.2 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.1 GO:0009378 four-way junction helicase activity(GO:0009378)
0.0 0.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.1 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.9 GO:0004520 endodeoxyribonuclease activity(GO:0004520)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.9 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 REACTOME OPSINS Genes involved in Opsins
0.0 1.2 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 1.5 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.9 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.5 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 1.3 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.6 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.4 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.6 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.4 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.6 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.1 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.3 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.2 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 1.0 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation