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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for SPDEF

Z-value: 0.67

Motif logo

Transcription factors associated with SPDEF

Gene Symbol Gene ID Gene Info
ENSG00000124664.11 SPDEF

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SPDEFhg38_v1_chr6_-_34556319_34556339-0.067.7e-01Click!

Activity profile of SPDEF motif

Sorted Z-values of SPDEF motif

Network of associatons between targets according to the STRING database.

First level regulatory network of SPDEF

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr8_-_77000070 1.13 ENST00000357039.9
peroxisomal biogenesis factor 2
chr8_-_77000194 1.11 ENST00000522527.5
peroxisomal biogenesis factor 2
chr2_+_66435116 0.97 ENST00000272369.14
ENST00000560281.6
Meis homeobox 1
chr12_+_27244222 0.95 ENST00000545470.5
ENST00000389032.8
ENST00000540996.5
serine/threonine kinase 38 like
chr17_-_7205116 0.89 ENST00000649520.1
ENST00000649186.1
discs large MAGUK scaffold protein 4
chr2_+_66435558 0.84 ENST00000488550.5
Meis homeobox 1
chr5_+_77030360 0.74 ENST00000312916.12
ENST00000506806.1
angiogenic factor with G-patch and FHA domains 1
chr10_-_118046574 0.71 ENST00000369199.5
RAB11 family interacting protein 2
chr7_+_93921720 0.70 ENST00000248564.6
G protein subunit gamma 11
chr2_+_147844488 0.69 ENST00000535787.5
activin A receptor type 2A
chr12_+_29149238 0.67 ENST00000536681.8
fatty acyl-CoA reductase 2
chr10_-_118046922 0.65 ENST00000355624.8
RAB11 family interacting protein 2
chr6_-_139374605 0.63 ENST00000618718.1
ENST00000367651.4
Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2
chr5_+_161848536 0.62 ENST00000519621.2
ENST00000636573.1
gamma-aminobutyric acid type A receptor subunit alpha1
chr11_-_118252279 0.62 ENST00000525386.5
ENST00000527472.1
ENST00000278949.9
myelin protein zero like 3
chr2_-_128027273 0.60 ENST00000259235.7
ENST00000357702.9
ENST00000424298.5
Sin3A associated protein 130
chr16_+_77191173 0.59 ENST00000248248.8
ENST00000439557.6
ENST00000545553.1
MON1 homolog B, secretory trafficking associated
chr14_+_73950489 0.59 ENST00000554320.1
coenzyme Q6, monooxygenase
chr1_+_84164370 0.59 ENST00000446538.5
ENST00000610703.4
ENST00000370682.7
ENST00000394838.6
ENST00000432111.5
protein kinase cAMP-activated catalytic subunit beta
chr2_-_128028010 0.58 ENST00000643581.2
ENST00000450957.1
Sin3A associated protein 130
chr5_+_31532277 0.58 ENST00000507818.6
ENST00000325366.14
chromosome 5 open reading frame 22
chr17_+_49788672 0.58 ENST00000454930.6
ENST00000259021.9
ENST00000509773.5
ENST00000510819.5
ENST00000424009.6
lysine acetyltransferase 7
chr14_+_59484443 0.57 ENST00000356057.9
ENST00000425728.6
ENST00000616435.5
ENST00000556985.5
ENST00000554271.5
ENST00000554795.1
JNK1/MAPK8 associated membrane protein
chr17_-_49677976 0.54 ENST00000665825.1
ENST00000508805.5
ENST00000515508.6
ENST00000451526.6
ENST00000507970.5
speckle type BTB/POZ protein
chr1_+_84164962 0.53 ENST00000614872.4
ENST00000394839.6
protein kinase cAMP-activated catalytic subunit beta
chr12_+_109052564 0.52 ENST00000257548.10
ENST00000536723.5
ENST00000536393.5
ubiquitin specific peptidase 30
chr4_-_39638893 0.52 ENST00000511809.5
ENST00000505729.1
small integral membrane protein 14
chr12_+_118376539 0.51 ENST00000543473.2
SDS3 homolog, SIN3A corepressor complex component
chr10_-_124744280 0.49 ENST00000337318.8
family with sequence similarity 53 member B
chr5_-_31532039 0.49 ENST00000511367.6
ENST00000344624.8
ENST00000513349.5
drosha ribonuclease III
chr14_-_31457417 0.48 ENST00000356180.4
D-aminoacyl-tRNA deacylase 2
chr4_+_165207552 0.47 ENST00000226725.11
kelch like family member 2
chr17_-_49678074 0.46 ENST00000505581.5
ENST00000504102.6
ENST00000514121.6
ENST00000393328.6
ENST00000509079.6
ENST00000347630.6
speckle type BTB/POZ protein
chr15_+_55408479 0.46 ENST00000569691.2
chromosome 15 open reading frame 65
chr17_-_35578535 0.45 ENST00000225873.9
peroxisomal biogenesis factor 12
chr10_-_14954018 0.44 ENST00000378241.5
ENST00000456122.1
ENST00000418843.5
ENST00000378249.5
ENST00000396817.6
ENST00000378255.5
ENST00000378254.5
ENST00000357717.6
ENST00000378258.5
ENST00000378246.6
ENST00000378278.7
DNA cross-link repair 1C
chr3_+_29280945 0.44 ENST00000434693.6
RNA binding motif single stranded interacting protein 3
chr4_+_143184910 0.44 ENST00000510377.5
ENST00000307017.9
ubiquitin specific peptidase 38
chr3_+_29281049 0.43 ENST00000383767.7
RNA binding motif single stranded interacting protein 3
chr6_-_138987640 0.43 ENST00000529597.5
ENST00000415951.6
ENST00000367663.8
ENST00000409812.6
RALBP1 associated Eps domain containing 1
chr6_-_138988241 0.43 ENST00000450536.7
ENST00000626459.2
ENST00000258062.9
RALBP1 associated Eps domain containing 1
chr3_+_113897470 0.42 ENST00000440446.2
ENST00000488680.1
GRAM domain containing 1C
chr12_-_64222239 0.42 ENST00000311915.12
ENST00000398055.8
ENST00000544871.1
chromosome 12 open reading frame 66
chr12_-_122716790 0.42 ENST00000528880.3
hydroxycarboxylic acid receptor 3
chr15_-_55408018 0.41 ENST00000569205.5
cell cycle progression 1
chr1_-_28643005 0.40 ENST00000263974.4
ENST00000373824.9
ENST00000495422.2
TATA-box binding protein associated factor 12
chr1_-_110963897 0.39 ENST00000369763.5
ligand dependent nuclear receptor interacting factor 1
chr5_+_110738983 0.39 ENST00000355943.8
ENST00000447245.6
solute carrier family 25 member 46
chr12_-_6689450 0.39 ENST00000355772.8
ENST00000417772.7
ENST00000319770.7
ENST00000396801.7
zinc finger protein 384
chr7_+_77798832 0.39 ENST00000415251.6
ENST00000275575.11
putative homeodomain transcription factor 2
chr1_-_110963936 0.39 ENST00000485275.2
ligand dependent nuclear receptor interacting factor 1
chr20_+_62122423 0.38 ENST00000370915.5
ENST00000279068.11
ENST00000400318.6
ENST00000279069.11
LSM family member 14B
chr10_-_124744254 0.36 ENST00000280780.6
family with sequence similarity 53 member B
chr12_-_132329532 0.35 ENST00000328957.13
polypeptide N-acetylgalactosaminyltransferase 9
chr5_+_159263282 0.34 ENST00000296786.8
ubiquitin like domain containing CTD phosphatase 1
chr19_-_36054224 0.34 ENST00000292894.2
THAP domain containing 8
chr1_-_197201262 0.34 ENST00000367405.5
zinc finger and BTB domain containing 41
chrX_-_130268883 0.33 ENST00000447817.1
ENST00000370978.9
zinc finger protein 280C
chr2_+_219597838 0.33 ENST00000456909.6
serine/threonine kinase 11 interacting protein
chr1_+_966466 0.33 ENST00000379410.8
ENST00000379407.7
ENST00000379409.6
pleckstrin homology domain containing N1
chr14_-_31457495 0.32 ENST00000310850.9
D-aminoacyl-tRNA deacylase 2
chr9_-_83956677 0.32 ENST00000376344.8
chromosome 9 open reading frame 64
chr7_+_77798750 0.32 ENST00000416283.6
ENST00000422959.6
ENST00000307305.12
ENST00000424760.5
putative homeodomain transcription factor 2
chr12_-_6689244 0.32 ENST00000361959.7
ENST00000436774.6
ENST00000544482.1
zinc finger protein 384
chr2_+_147844601 0.31 ENST00000404590.1
activin A receptor type 2A
chr1_+_66930239 0.31 ENST00000401042.7
ENST00000355356.3
MIER1 transcriptional regulator
chr12_-_6689359 0.31 ENST00000683879.1
zinc finger protein 384
chr11_+_36594369 0.31 ENST00000678060.1
ENST00000446510.6
ENST00000676979.1
ENST00000677808.1
ENST00000617650.5
ENST00000334307.10
ENST00000531554.6
ENST00000679022.1
ENST00000347206.8
ENST00000534635.5
ENST00000676921.1
ENST00000678950.1
ENST00000530697.6
ENST00000527108.6
ENST00000532470.3
intraflagellar transport associated protein
chr6_+_133953210 0.31 ENST00000367869.1
ENST00000237264.9
ENST00000674115.1
TATA-box binding protein like 1
novel protein
chr15_-_63157464 0.31 ENST00000330964.10
ENST00000635699.1
ENST00000439025.1
ribosomal protein S27 like
chr17_-_37609361 0.29 ENST00000614941.4
ENST00000619541.4
ENST00000622045.4
ENST00000616179.4
ENST00000621136.4
ENST00000612223.5
ENST00000620424.1
synergin gamma
chr12_+_106358082 0.29 ENST00000539066.5
RNA polymerase III subunit B
chr9_-_69759994 0.29 ENST00000340434.5
protein prenyltransferase alpha subunit repeat containing 1
chr4_-_39638846 0.29 ENST00000295958.10
small integral membrane protein 14
chr12_+_123384078 0.28 ENST00000402868.8
lysine methyltransferase 5A
chr9_-_69759932 0.28 ENST00000377200.9
ENST00000472967.2
protein prenyltransferase alpha subunit repeat containing 1
chr2_+_218672027 0.28 ENST00000392105.7
ENST00000455724.5
ENST00000295709.8
serine/threonine kinase 36
chr2_-_63588390 0.28 ENST00000272321.12
ENST00000409562.7
WD repeat containing planar cell polarity effector
chr2_+_27582969 0.27 ENST00000556601.5
ENST00000413371.6
ENST00000416005.6
zinc finger protein 512
chr17_-_64662290 0.26 ENST00000262435.14
SMAD specific E3 ubiquitin protein ligase 2
chr2_+_27583015 0.26 ENST00000379717.5
ENST00000355467.6
ENST00000505973.1
zinc finger protein 512
novel transcript
chr20_-_20052389 0.26 ENST00000536226.2
crooked neck pre-mRNA splicing factor 1
chr12_+_106357729 0.26 ENST00000228347.9
RNA polymerase III subunit B
chr3_-_171809770 0.26 ENST00000331659.2
phospholipase D1
chr3_+_57556244 0.26 ENST00000311180.9
ENST00000487257.1
phosphodiesterase 12
chr7_+_100015572 0.25 ENST00000535170.5
zinc finger with KRAB and SCAN domains 1
chr7_-_77798359 0.25 ENST00000257663.4
transmembrane protein 60
chr4_+_152779934 0.25 ENST00000451320.6
ENST00000429148.6
ENST00000353617.7
ENST00000405727.6
ENST00000356064.3
ADP ribosylation factor interacting protein 1
chr14_+_24232422 0.24 ENST00000620807.4
ENST00000355299.8
ENST00000559836.5
guanosine monophosphate reductase 2
chr5_+_161848112 0.24 ENST00000393943.10
gamma-aminobutyric acid type A receptor subunit alpha1
chr5_+_161848314 0.24 ENST00000437025.6
gamma-aminobutyric acid type A receptor subunit alpha1
chr15_-_55408467 0.24 ENST00000310958.10
cell cycle progression 1
chr15_+_43371062 0.24 ENST00000260383.11
ENST00000564079.6
tubulin gamma complex associated protein 4
chr17_+_40287861 0.23 ENST00000209728.9
ENST00000580824.5
ENST00000577249.1
ENST00000649662.1
cell division cycle 6
chr1_-_193059296 0.23 ENST00000367450.7
ENST00000367451.8
ENST00000367454.6
ENST00000367448.5
ENST00000367449.5
ubiquitin C-terminal hydrolase L5
chr1_+_84164684 0.23 ENST00000370680.5
protein kinase cAMP-activated catalytic subunit beta
chr18_+_21740763 0.23 ENST00000261537.7
MIB E3 ubiquitin protein ligase 1
chr14_+_60249191 0.22 ENST00000395076.9
protein phosphatase, Mg2+/Mn2+ dependent 1A
chr7_-_92246045 0.22 ENST00000394507.5
ENST00000458177.6
ENST00000340022.6
ENST00000444960.5
KRIT1 ankyrin repeat containing
chr15_-_55408245 0.22 ENST00000563171.5
ENST00000425574.7
ENST00000442196.8
ENST00000564092.1
cell cycle progression 1
chr1_+_235328959 0.22 ENST00000643758.1
ENST00000497327.1
tubulin folding cofactor E
geranylgeranyl diphosphate synthase 1
chr14_+_73950252 0.22 ENST00000629426.2
coenzyme Q6, monooxygenase
chr11_+_61362355 0.22 ENST00000542946.1
ENST00000278826.11
transmembrane protein 138
chr12_+_131949893 0.22 ENST00000389561.7
ENST00000332482.8
ENST00000333577.8
E1A binding protein p400
chr1_+_235328399 0.22 ENST00000471812.5
ENST00000358966.6
ENST00000282841.9
ENST00000391855.2
ENST00000647428.1
ENST00000645655.1
ENST00000647186.1
ENST00000646624.1
ENST00000645205.1
ENST00000645351.1
geranylgeranyl diphosphate synthase 1
tubulin folding cofactor E
chr14_-_77616630 0.21 ENST00000216484.7
serine palmitoyltransferase long chain base subunit 2
chr2_+_101002229 0.21 ENST00000409000.5
ENST00000409028.8
ENST00000264258.8
ENST00000409320.7
ENST00000409733.5
ENST00000409650.5
ENST00000409038.5
ribosomal protein L31
chr11_-_66347560 0.21 ENST00000311181.5
beta-1,4-glucuronyltransferase 1
chr7_-_38909174 0.21 ENST00000395969.6
ENST00000310301.9
ENST00000414632.5
VPS41 subunit of HOPS complex
chr11_+_112086853 0.20 ENST00000528182.5
ENST00000528048.5
ENST00000375549.8
ENST00000528021.6
ENST00000526592.5
ENST00000525291.5
succinate dehydrogenase complex subunit D
chr14_+_24232612 0.20 ENST00000560139.5
ENST00000559910.5
ENST00000348719.11
guanosine monophosphate reductase 2
chr11_-_130916437 0.20 ENST00000533214.1
ENST00000528555.5
ENST00000530356.5
ENST00000265909.9
sorting nexin 19
chr1_-_193059489 0.20 ENST00000367455.8
ENST00000421683.1
ubiquitin C-terminal hydrolase L5
chr14_+_73950285 0.20 ENST00000334571.7
ENST00000554920.5
coenzyme Q6, monooxygenase
chr2_+_218672291 0.20 ENST00000440309.5
ENST00000424080.1
serine/threonine kinase 36
chr2_+_137964446 0.20 ENST00000280096.5
ENST00000280097.5
histamine N-methyltransferase
chr8_-_129939872 0.20 ENST00000519540.5
CYFIP related Rac1 interactor B
chr1_+_52602347 0.20 ENST00000361314.5
glutathione peroxidase 7
chr8_+_99013247 0.19 ENST00000441350.2
ENST00000357162.7
ENST00000358544.7
vacuolar protein sorting 13 homolog B
chr17_-_47831509 0.19 ENST00000414011.1
ENST00000351111.7
mitochondrial ribosomal protein L10
chr7_-_92245795 0.18 ENST00000412043.6
ENST00000430102.5
ENST00000425073.1
ENST00000394505.7
ENST00000394503.6
ENST00000454017.5
ENST00000440209.5
ENST00000413688.5
ENST00000452773.5
ENST00000433016.5
ENST00000422347.5
ENST00000458493.5
ENST00000425919.5
ENST00000650585.1
KRIT1 ankyrin repeat containing
novel protein
chr1_-_61725121 0.18 ENST00000371177.2
ENST00000606498.5
TM2 domain containing 1
chr8_-_130016395 0.18 ENST00000523509.5
CYFIP related Rac1 interactor B
chr7_+_100015588 0.18 ENST00000324306.11
ENST00000426572.5
zinc finger with KRAB and SCAN domains 1
chr6_-_31592992 0.18 ENST00000340027.10
natural cytotoxicity triggering receptor 3
chr8_-_130016414 0.18 ENST00000401979.6
ENST00000517654.5
ENST00000522361.1
ENST00000518167.5
CYFIP related Rac1 interactor B
chr5_+_87268922 0.18 ENST00000456692.6
ENST00000512763.5
ENST00000506290.1
RAS p21 protein activator 1
chr1_+_169368175 0.17 ENST00000367808.8
ENST00000426663.1
basic leucine zipper nuclear factor 1
chr3_-_138174879 0.17 ENST00000260803.9
debranching RNA lariats 1
chr15_-_43371017 0.17 ENST00000684362.1
zinc finger and SCAN domain containing 29
chr3_-_94062906 0.17 ENST00000314636.3
ENST00000394221.3
dihydrofolate reductase 2
chrX_+_153179276 0.17 ENST00000356661.7
MAGE family member A1
chr1_-_184754808 0.17 ENST00000318130.13
ENST00000367512.7
ER degradation enhancing alpha-mannosidase like protein 3
chr8_-_130016622 0.17 ENST00000518283.5
ENST00000519110.5
CYFIP related Rac1 interactor B
chr20_-_35699317 0.17 ENST00000397425.5
ENST00000374092.9
ENST00000541387.5
NFS1 cysteine desulfurase
chr3_-_69052309 0.17 ENST00000398559.7
ENST00000646708.1
ENST00000646304.1
TATA element modulatory factor 1
chr7_+_114922346 0.16 ENST00000393486.5
MyoD family inhibitor domain containing
chr22_-_21982748 0.16 ENST00000398793.6
ENST00000437929.5
ENST00000456075.5
ENST00000434517.1
ENST00000424393.5
ENST00000357179.10
ENST00000449704.5
ENST00000437103.1
DNA topoisomerase III beta
chr7_+_10973864 0.15 ENST00000403050.7
ENST00000634607.2
PHD finger protein 14
chr1_+_151070740 0.15 ENST00000368918.8
GA binding protein transcription factor subunit beta 2
chr1_-_153922901 0.15 ENST00000634401.1
ENST00000368655.5
GATA zinc finger domain containing 2B
chr2_+_197516039 0.15 ENST00000448447.6
ENST00000323303.9
ENST00000409360.1
MOB family member 4, phocein
chr17_-_44014946 0.15 ENST00000587529.1
ENST00000206380.8
transmembrane protein 101
chr2_+_197515565 0.15 ENST00000233892.8
ENST00000409916.5
MOB family member 4, phocein
chr5_+_100535317 0.15 ENST00000312637.5
family with sequence similarity 174 member A
chr14_+_88562952 0.15 ENST00000302216.12
ENST00000554602.5
ENST00000556945.5
ENST00000556158.5
ENST00000557607.5
ENST00000555799.5
ENST00000251038.10
ENST00000555755.5
zinc finger CCCH-type containing 14
chr9_-_137221323 0.15 ENST00000391553.2
ENST00000392827.2
ring finger protein 208
chr2_-_37084302 0.15 ENST00000233099.6
HEAT repeat containing 5B
chr2_+_48440757 0.14 ENST00000294952.13
ENST00000281394.8
ENST00000449090.6
protein phosphatase 1 regulatory subunit 21
chr18_+_24426633 0.14 ENST00000648078.1
ENST00000284202.9
impact RWD domain protein
chr4_+_158672266 0.14 ENST00000684622.1
ENST00000683483.1
ENST00000684641.1
ENST00000682456.1
ENST00000684627.1
ENST00000511912.6
ENST00000684505.1
ENST00000683305.1
ENST00000684036.1
ENST00000683751.1
ENST00000684129.1
ENST00000307738.5
electron transfer flavoprotein dehydrogenase
chr4_+_158672237 0.14 ENST00000682734.1
electron transfer flavoprotein dehydrogenase
chr3_-_133661896 0.13 ENST00000260810.10
DNA topoisomerase II binding protein 1
chr6_-_31592952 0.13 ENST00000376073.8
ENST00000376072.7
natural cytotoxicity triggering receptor 3
chr4_+_48831217 0.13 ENST00000510824.5
ENST00000425583.6
OCIA domain containing 1
chr1_+_171781635 0.13 ENST00000361735.4
ENST00000362019.7
ENST00000367737.9
eEF1A lysine and N-terminal methyltransferase
chr19_-_4723749 0.13 ENST00000597849.5
ENST00000598800.5
ENST00000602161.5
ENST00000262960.14
ENST00000597726.5
ENST00000601130.5
dipeptidyl peptidase 9
chrX_+_124346525 0.13 ENST00000360027.4
SH2 domain containing 1A
chr2_+_37084440 0.12 ENST00000409774.6
G-patch domain containing 11
chr14_-_75126964 0.12 ENST00000678037.1
ENST00000553823.6
ENST00000678531.1
ENST00000238616.10
NIMA related kinase 9
chr5_+_94618653 0.12 ENST00000265140.10
ENST00000504099.5
SMC5-SMC6 complex localization factor 1
chr2_+_37084486 0.12 ENST00000281932.6
ENST00000674370.2
G-patch domain containing 11
chr2_-_38875872 0.12 ENST00000457308.6
ENST00000619207.1
DExH-box helicase 57
chr3_+_33798557 0.12 ENST00000457054.6
ENST00000413073.1
ENST00000307296.8
programmed cell death 6 interacting protein
chr12_+_50400809 0.12 ENST00000293618.12
ENST00000429001.7
ENST00000398473.7
ENST00000548174.5
ENST00000548697.5
ENST00000548993.5
ENST00000614335.4
ENST00000522085.5
ENST00000615080.4
ENST00000518444.5
ENST00000551886.5
ENST00000523389.5
ENST00000518561.5
ENST00000347328.9
ENST00000550260.1
La ribonucleoprotein 4
chr4_+_48830998 0.12 ENST00000509122.5
ENST00000509664.5
ENST00000505922.6
ENST00000514981.5
ENST00000511662.5
ENST00000508996.5
ENST00000507210.5
ENST00000396448.6
ENST00000512236.5
ENST00000509164.5
ENST00000511102.5
ENST00000381473.7
ENST00000264312.12
ENST00000444354.6
ENST00000509963.5
ENST00000509246.5
OCIA domain containing 1
chr12_+_102120172 0.12 ENST00000327680.7
ENST00000541394.5
ENST00000543784.5
PARP1 binding protein
chr4_+_140524147 0.12 ENST00000511887.6
ENST00000323570.8
ELMO domain containing 2
chr8_-_116755784 0.11 ENST00000518949.5
ENST00000522453.1
ENST00000518995.5
ENST00000521861.6
ENST00000611080.1
eukaryotic translation initiation factor 3 subunit H
chr20_-_35699181 0.11 ENST00000374085.5
ENST00000419569.5
NFS1 cysteine desulfurase
chr2_+_96266211 0.11 ENST00000488633.2
cytosolic iron-sulfur assembly component 1
chr11_+_65615755 0.11 ENST00000355703.4
pecanex 3
chr1_-_67430386 0.11 ENST00000370995.6
ENST00000361219.11
SERPINE1 mRNA binding protein 1
chr4_+_48831166 0.11 ENST00000503016.5
OCIA domain containing 1
chr10_-_15860450 0.11 ENST00000277632.8
MINDY lysine 48 deubiquitinase 3
chrX_-_123733023 0.11 ENST00000245838.13
ENST00000355725.8
THO complex 2
chrX_+_124346544 0.11 ENST00000371139.9
SH2 domain containing 1A
chr1_-_169367746 0.11 ENST00000367811.8
ENST00000472647.5
NME/NM23 family member 7
chr7_+_128739395 0.11 ENST00000479257.5
calumenin
chr22_+_37805218 0.11 ENST00000340857.4
H1.0 linker histone
chr14_-_59484317 0.11 ENST00000247194.9
trans-L-3-hydroxyproline dehydratase
chr3_-_139389604 0.10 ENST00000515006.5
ENST00000510181.6
ENST00000333188.10
ENST00000513274.5
ENST00000514508.2
ENST00000503326.6
ENST00000507777.6
ENST00000512242.6
ENST00000512153.5
ENST00000512309.2
COPI coat complex subunit beta 2
chr6_-_41286665 0.10 ENST00000589614.5
ENST00000244709.9
ENST00000334475.10
ENST00000591620.1
triggering receptor expressed on myeloid cells 1
chr8_-_56074492 0.10 ENST00000518875.5
ENST00000524349.5
ENST00000009589.8
ENST00000519606.5
ENST00000519807.5
ENST00000520627.1
ENST00000521262.5
ribosomal protein S20
chr19_+_36687579 0.10 ENST00000682579.1
ENST00000536254.6
zinc finger protein 567
chr1_-_235161215 0.10 ENST00000447801.5
ENST00000408888.8
ENST00000429912.1
RNA binding motif protein 34
chr9_-_86947496 0.09 ENST00000298743.9
growth arrest specific 1
chr4_+_48831142 0.09 ENST00000506801.5
OCIA domain containing 1
chr1_-_67430412 0.09 ENST00000370994.8
SERPINE1 mRNA binding protein 1
chrX_-_136880715 0.09 ENST00000431446.7
ENST00000320676.11
ENST00000562646.5
RNA binding motif protein X-linked
chr3_-_156555083 0.09 ENST00000265044.7
ENST00000476217.5
signal sequence receptor subunit 3
chr4_-_674246 0.09 ENST00000304312.5
ATP synthase membrane subunit e
chr14_-_73950075 0.08 ENST00000286544.5
FAM161 centrosomal protein B
chr20_-_35411963 0.08 ENST00000349714.9
ENST00000438533.5
ENST00000359226.6
ENST00000374384.6
ENST00000374385.10
ENST00000424405.5
ENST00000397554.5
ENST00000374380.6
ubiquinol-cytochrome c reductase complex assembly factor 1
chr2_+_161308407 0.08 ENST00000409682.8
proteasome 26S subunit, non-ATPase 14
chr1_-_67430320 0.08 ENST00000370990.5
SERPINE1 mRNA binding protein 1
chr18_+_23453275 0.08 ENST00000581585.5
ENST00000339486.8
ENST00000577501.5
RIO kinase 3
chr8_+_22604632 0.08 ENST00000308511.8
ENST00000523801.5
ENST00000521301.5
cell cycle and apoptosis regulator 2
chr7_-_6059139 0.08 ENST00000446699.1
ENST00000199389.11
eukaryotic translation initiation factor 2 alpha kinase 1
chr2_+_3379668 0.07 ENST00000382110.6
ENST00000324266.10
trafficking protein particle complex 12

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0072720 response to dithiothreitol(GO:0072720)
0.2 1.3 GO:0097338 response to clozapine(GO:0097338)
0.1 0.9 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.1 0.4 GO:0033385 geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.1 1.0 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.1 0.5 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.1 0.4 GO:0090149 mitochondrial membrane fission(GO:0090149)
0.1 0.6 GO:0035802 adrenal cortex development(GO:0035801) adrenal cortex formation(GO:0035802) negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.1 2.7 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.1 0.7 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.1 0.6 GO:0019086 late viral transcription(GO:0019086)
0.1 0.5 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
0.1 0.3 GO:0016476 regulation of embryonic cell shape(GO:0016476)
0.1 0.9 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1 1.8 GO:0060044 negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.1 0.3 GO:0018282 metal incorporation into metallo-sulfur cluster(GO:0018282) iron incorporation into metallo-sulfur cluster(GO:0018283)
0.1 0.2 GO:0006667 sphinganine metabolic process(GO:0006667)
0.1 0.3 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.1 0.2 GO:1904116 response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117)
0.1 0.3 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.1 0.8 GO:0097688 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.1 0.2 GO:2000583 regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
0.1 0.2 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.1 0.2 GO:1990502 dense core granule maturation(GO:1990502)
0.0 0.8 GO:0006450 regulation of translational fidelity(GO:0006450)
0.0 0.3 GO:0001692 histamine metabolic process(GO:0001692)
0.0 0.3 GO:0006235 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
0.0 0.2 GO:0097466 protein deglycosylation involved in glycoprotein catabolic process(GO:0035977) glycoprotein ERAD pathway(GO:0097466) mannose trimming involved in glycoprotein ERAD pathway(GO:1904382)
0.0 0.2 GO:2000845 testosterone secretion(GO:0035936) regulation of testosterone secretion(GO:2000843) positive regulation of testosterone secretion(GO:2000845)
0.0 1.1 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.6 GO:0097354 protein prenylation(GO:0018342) prenylation(GO:0097354)
0.0 0.5 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.0 0.4 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.0 0.2 GO:0030311 poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.2 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.0 0.1 GO:0034184 positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184) protein localization to site of double-strand break(GO:1990166)
0.0 0.2 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0 0.1 GO:0044837 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.0 0.8 GO:1901663 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.3 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.1 GO:0071494 positive regulation of translational initiation in response to stress(GO:0032058) cellular response to UV-C(GO:0071494)
0.0 0.1 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.0 0.3 GO:0031937 positive regulation of chromatin silencing(GO:0031937)
0.0 0.2 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.0 0.1 GO:0006447 regulation of translational initiation by iron(GO:0006447)
0.0 0.1 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.0 1.4 GO:0003091 renal water homeostasis(GO:0003091)
0.0 0.4 GO:0021670 lateral ventricle development(GO:0021670)
0.0 0.7 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.0 0.4 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.1 GO:0070945 neutrophil mediated killing of gram-negative bacterium(GO:0070945)
0.0 0.3 GO:0034770 histone H4-K20 methylation(GO:0034770)
0.0 0.8 GO:0035411 catenin import into nucleus(GO:0035411)
0.0 0.4 GO:0043101 purine-containing compound salvage(GO:0043101)
0.0 0.3 GO:0045954 positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.0 0.3 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.3 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.1 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.2 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.0 0.0 GO:1902164 regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.0 0.1 GO:0051182 coenzyme transport(GO:0051182)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.2 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.2 1.0 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.1 0.4 GO:1902560 GMP reductase complex(GO:1902560)
0.1 1.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 1.7 GO:0070822 Sin3-type complex(GO:0070822)
0.0 0.1 GO:0044609 DBIRD complex(GO:0044609)
0.0 0.8 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 0.3 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
0.0 0.2 GO:0045281 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 1.2 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.3 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.4 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.0 0.2 GO:0000923 equatorial microtubule organizing center(GO:0000923)
0.0 0.1 GO:0071817 MMXD complex(GO:0071817)
0.0 0.5 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.0 0.4 GO:0000124 SAGA complex(GO:0000124)
0.0 1.1 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.2 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.2 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.1 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 1.5 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.2 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.5 GO:1902555 endoribonuclease complex(GO:1902555)
0.0 0.1 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.2 GO:0000812 Swr1 complex(GO:0000812)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0051500 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.1 0.7 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.1 1.0 GO:0098821 BMP receptor activity(GO:0098821)
0.1 1.1 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.1 0.8 GO:0031812 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.1 0.3 GO:0031071 cysteine desulfurase activity(GO:0031071)
0.1 0.3 GO:0016649 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.1 0.4 GO:0016657 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.1 0.4 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.1 1.3 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 0.5 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.1 0.6 GO:0008318 protein prenyltransferase activity(GO:0008318)
0.1 0.2 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.0 0.2 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.4 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.6 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.1 GO:0036361 racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661)
0.0 0.2 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 0.6 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.2 GO:0004096 catalase activity(GO:0004096)
0.0 1.0 GO:0071949 FAD binding(GO:0071949)
0.0 0.3 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.3 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.2 GO:1990405 protein antigen binding(GO:1990405)
0.0 0.2 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.5 GO:0070628 proteasome binding(GO:0070628)
0.0 0.8 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.0 0.2 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.1 GO:0016807 cysteine-type carboxypeptidase activity(GO:0016807) cysteine-type exopeptidase activity(GO:0070004)
0.0 0.1 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.1 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.3 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.3 GO:0008494 translation activator activity(GO:0008494)
0.0 0.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.1 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0 1.8 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.3 PID IL3 PATHWAY IL3-mediated signaling events
0.0 1.1 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.4 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.6 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.6 PID HIF2PATHWAY HIF-2-alpha transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.3 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 2.1 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 1.1 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.7 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.9 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.4 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.5 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.5 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 0.2 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.2 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle