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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for SPIB

Z-value: 0.84

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Transcription factors associated with SPIB

Gene Symbol Gene ID Gene Info
SPIB
ENSG00000269404.7 SPIB

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SPIBhg38_v1_chr19_+_50418930_504189580.048.6e-01Click!

Activity profile of SPIB motif

Sorted Z-values of SPIB motif

Network of associatons between targets according to the STRING database.

First level regulatory network of SPIB

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr6_+_135851681 1.51 ENST00000308191.11
PDE7B
phosphodiesterase 7B
chr2_-_224401994 1.46 ENST00000389874.3
FAM124B
family with sequence similarity 124 member B
chr2_-_224402097 1.45 ENST00000409685.4
FAM124B
family with sequence similarity 124 member B
chr19_-_13102848 1.37 ENST00000264824.5
LYL1
LYL1 basic helix-loop-helix family member
chr13_+_57631735 1.30 ENST00000377918.8
PCDH17
protocadherin 17
chr22_+_19760714 1.25 ENST00000649276.2
TBX1
T-box transcription factor 1
chr19_+_45469841 1.08 ENST00000592811.5
ENST00000586615.5
FOSB
FosB proto-oncogene, AP-1 transcription factor subunit
chr1_-_121183911 1.06 ENST00000355228.8
FAM72B
family with sequence similarity 72 member B
chr14_+_73950489 1.06 ENST00000554320.1
COQ6
coenzyme Q6, monooxygenase
chr19_+_2476118 1.05 ENST00000215631.9
ENST00000587345.1
GADD45B
growth arrest and DNA damage inducible beta
chr16_+_30949054 1.03 ENST00000318663.5
ENST00000566237.1
ENST00000562699.1
ORAI3
ORAI calcium release-activated calcium modulator 3
chr1_-_206202419 1.00 ENST00000607379.1
ENST00000341209.9
FAM72A
family with sequence similarity 72 member A
chr16_-_4800470 1.00 ENST00000592019.1
ENST00000586153.1
ROGDI
rogdi atypical leucine zipper
chr2_+_233059838 0.97 ENST00000359570.9
INPP5D
inositol polyphosphate-5-phosphatase D
chr2_+_233060295 0.97 ENST00000445964.6
INPP5D
inositol polyphosphate-5-phosphatase D
chr17_-_74712911 0.94 ENST00000326165.11
ENST00000583937.5
ENST00000301573.13
ENST00000469092.5
CD300LF
CD300 molecule like family member f
chr8_-_77000194 0.89 ENST00000522527.5
PEX2
peroxisomal biogenesis factor 2
chr7_+_74773962 0.74 ENST00000289473.10
NCF1
neutrophil cytosolic factor 1
chr1_-_153946652 0.73 ENST00000361217.9
DENND4B
DENN domain containing 4B
chr19_-_17264718 0.73 ENST00000431146.6
ENST00000594190.5
USHBP1
USH1 protein network component harmonin binding protein 1
chr1_+_159302321 0.69 ENST00000368114.1
FCER1A
Fc fragment of IgE receptor Ia
chr22_-_37519528 0.68 ENST00000403299.5
CARD10
caspase recruitment domain family member 10
chr22_-_37519349 0.68 ENST00000251973.10
CARD10
caspase recruitment domain family member 10
chr17_-_19046957 0.65 ENST00000284154.10
ENST00000573099.5
GRAP
GRB2 related adaptor protein
chr13_+_30735523 0.64 ENST00000380490.5
ALOX5AP
arachidonate 5-lipoxygenase activating protein
chr13_+_30713477 0.63 ENST00000617770.4
ALOX5AP
arachidonate 5-lipoxygenase activating protein
chrX_-_75156272 0.63 ENST00000620875.5
ENST00000669573.1
ENST00000339447.8
ENST00000645829.3
ENST00000529949.5
ENST00000373394.8
ENST00000253577.9
ENST00000644766.1
ENST00000534524.5
ABCB7
ATP binding cassette subfamily B member 7
chr12_-_14961256 0.62 ENST00000541380.5
ARHGDIB
Rho GDP dissociation inhibitor beta
chr17_-_31314066 0.62 ENST00000577894.1
EVI2B
ecotropic viral integration site 2B
chr1_-_121184292 0.62 ENST00000452190.2
ENST00000619376.4
ENST00000369390.7
FAM72B
family with sequence similarity 72 member B
chr6_-_109094819 0.61 ENST00000436639.6
SESN1
sestrin 1
chr3_-_116444983 0.61 ENST00000333617.8
LSAMP
limbic system associated membrane protein
chr1_-_143971965 0.61 ENST00000369175.4
ENST00000584486.6
FAM72C
family with sequence similarity 72 member C
chr7_-_36724543 0.60 ENST00000612871.4
AOAH
acyloxyacyl hydrolase
chr7_-_36724380 0.58 ENST00000617267.4
AOAH
acyloxyacyl hydrolase
chr17_+_7558296 0.58 ENST00000438470.5
ENST00000436057.5
TNFSF13
TNF superfamily member 13
chr11_-_64803152 0.58 ENST00000439069.5
ENST00000294066.7
ENST00000377350.7
MAP4K2
mitogen-activated protein kinase kinase kinase kinase 2
chr8_+_73991345 0.57 ENST00000284818.7
ENST00000518893.1
LY96
lymphocyte antigen 96
chr11_+_64340191 0.56 ENST00000356786.10
CCDC88B
coiled-coil domain containing 88B
chr7_-_36724457 0.56 ENST00000617537.5
ENST00000435386.1
AOAH
acyloxyacyl hydrolase
chr13_+_108269880 0.55 ENST00000542136.1
TNFSF13B
TNF superfamily member 13b
chr7_-_138755892 0.52 ENST00000644341.1
ENST00000478480.2
ATP6V0A4
ATPase H+ transporting V0 subunit a4
chr6_-_132513045 0.52 ENST00000367941.7
ENST00000367937.4
STX7
syntaxin 7
chr1_-_206202827 0.51 ENST00000431655.2
ENST00000367128.8
FAM72A
family with sequence similarity 72 member A
chr14_+_66824439 0.51 ENST00000555456.1
GPHN
gephyrin
chr11_+_47269363 0.49 ENST00000342922.8
MADD
MAP kinase activating death domain
chr8_+_124973288 0.49 ENST00000319286.6
ZNF572
zinc finger protein 572
chr1_+_145095967 0.49 ENST00000400889.3
FAM72D
family with sequence similarity 72 member D
chr9_-_21995262 0.47 ENST00000494262.5
CDKN2A
cyclin dependent kinase inhibitor 2A
chr12_-_27014300 0.46 ENST00000535819.1
ENST00000543803.5
ENST00000535423.5
ENST00000539741.5
ENST00000343028.9
ENST00000545600.1
ENST00000543088.5
TM7SF3
transmembrane 7 superfamily member 3
chr9_+_101533840 0.46 ENST00000389120.8
ENST00000374819.6
ENST00000479306.5
RNF20
ring finger protein 20
chr16_+_54930827 0.45 ENST00000394636.9
IRX5
iroquois homeobox 5
chr9_+_127611760 0.45 ENST00000625363.2
ENST00000626539.3
STXBP1
syntaxin binding protein 1
chr17_-_5234801 0.45 ENST00000571800.5
ENST00000574081.6
ENST00000399600.8
ENST00000574297.1
SCIMP
SLP adaptor and CSK interacting membrane protein
chr9_+_127612222 0.44 ENST00000637953.1
ENST00000636962.2
STXBP1
syntaxin binding protein 1
chr16_+_57542635 0.44 ENST00000349457.8
ADGRG5
adhesion G protein-coupled receptor G5
chr16_+_57542672 0.44 ENST00000615867.4
ENST00000340339.4
ADGRG5
adhesion G protein-coupled receptor G5
chr6_-_144064511 0.44 ENST00000626373.2
ENST00000628651.2
ENST00000626294.2
ENST00000437412.5
ENST00000444202.5
ENST00000626462.2
ENST00000627449.2
PLAGL1
PLAG1 like zinc finger 1
chr9_+_127612257 0.43 ENST00000637173.2
ENST00000630492.2
ENST00000627871.2
ENST00000373302.8
ENST00000373299.5
ENST00000650920.1
ENST00000476182.3
STXBP1
syntaxin binding protein 1
chr19_-_38426162 0.43 ENST00000587738.2
ENST00000586305.5
RASGRP4
RAS guanyl releasing protein 4
chr19_-_48363914 0.43 ENST00000377431.6
ENST00000293261.8
TMEM143
transmembrane protein 143
chr2_+_96326204 0.43 ENST00000420728.1
ENST00000361124.5
ITPRIPL1
ITPRIP like 1
chr9_-_96383675 0.42 ENST00000375257.2
ENST00000375259.9
ENST00000253270.13
SLC35D2
solute carrier family 35 member D2
chr6_+_15246054 0.42 ENST00000341776.7
JARID2
jumonji and AT-rich interaction domain containing 2
chr19_-_48364034 0.42 ENST00000435956.7
TMEM143
transmembrane protein 143
chr4_-_84966637 0.42 ENST00000295888.9
WDFY3
WD repeat and FYVE domain containing 3
chr19_+_41877267 0.41 ENST00000221972.8
ENST00000597454.1
ENST00000444740.2
CD79A
CD79a molecule
chr16_+_30183595 0.40 ENST00000219150.10
ENST00000570045.5
ENST00000565497.5
ENST00000570244.5
CORO1A
coronin 1A
chr6_+_130018565 0.40 ENST00000361794.7
ENST00000526087.5
ENST00000533560.5
L3MBTL3
L3MBTL histone methyl-lysine binding protein 3
chr9_+_117704168 0.40 ENST00000472304.2
ENST00000394487.5
TLR4
toll like receptor 4
chr15_-_33068143 0.40 ENST00000558197.1
FMN1
formin 1
chr19_-_17264732 0.39 ENST00000252597.8
USHBP1
USH1 protein network component harmonin binding protein 1
chr11_+_123358416 0.39 ENST00000638157.1
GRAMD1B
GRAM domain containing 1B
chr9_+_132978651 0.38 ENST00000636137.1
GFI1B
growth factor independent 1B transcriptional repressor
chr9_-_21995301 0.38 ENST00000498628.6
CDKN2A
cyclin dependent kinase inhibitor 2A
chr9_+_2017383 0.37 ENST00000382194.6
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr14_+_65412949 0.37 ENST00000674118.1
ENST00000553924.5
ENST00000358307.6
ENST00000557338.5
ENST00000554610.1
FUT8
fucosyltransferase 8
chr5_-_173328407 0.37 ENST00000265087.9
STC2
stanniocalcin 2
chr2_-_191014137 0.37 ENST00000673777.1
ENST00000673942.1
ENST00000424722.6
ENST00000392322.7
ENST00000361099.8
ENST00000392323.6
ENST00000673816.1
ENST00000673847.1
ENST00000673952.1
ENST00000540176.6
ENST00000673841.1
STAT1
signal transducer and activator of transcription 1
chr2_+_68365274 0.36 ENST00000234313.8
PLEK
pleckstrin
chrX_+_110003095 0.36 ENST00000372073.5
ENST00000372068.7
ENST00000288381.4
TMEM164
transmembrane protein 164
chr12_-_14961610 0.36 ENST00000542276.1
ARHGDIB
Rho GDP dissociation inhibitor beta
chr12_+_25052512 0.36 ENST00000557489.5
ENST00000354454.7
ENST00000536173.5
IRAG2
inositol 1,4,5-triphosphate receptor associated 2
chr1_+_161581339 0.36 ENST00000543859.5
ENST00000611236.1
FCGR2C
Fc fragment of IgG receptor IIc (gene/pseudogene)
chr17_-_4786433 0.36 ENST00000354194.4
VMO1
vitelline membrane outer layer 1 homolog
chr9_+_2017572 0.36 ENST00000637806.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr2_+_108621260 0.35 ENST00000409441.5
LIMS1
LIM zinc finger domain containing 1
chr6_-_154356735 0.35 ENST00000367220.8
ENST00000265198.8
ENST00000520261.1
IPCEF1
interaction protein for cytohesin exchange factors 1
chr7_-_13989658 0.35 ENST00000430479.6
ENST00000433547.1
ENST00000405192.6
ETV1
ETS variant transcription factor 1
chr19_-_31349408 0.34 ENST00000240587.5
TSHZ3
teashirt zinc finger homeobox 3
chr5_-_56116946 0.34 ENST00000434982.2
ANKRD55
ankyrin repeat domain 55
chr2_+_201260496 0.34 ENST00000323492.11
CASP8
caspase 8
chr19_-_38426195 0.34 ENST00000615439.5
ENST00000614135.4
ENST00000622174.4
ENST00000587753.5
ENST00000454404.6
ENST00000617966.4
ENST00000618320.4
ENST00000293062.13
ENST00000433821.6
ENST00000426920.6
RASGRP4
RAS guanyl releasing protein 4
chr6_+_49463360 0.34 ENST00000335783.4
CENPQ
centromere protein Q
chr20_-_20052389 0.34 ENST00000536226.2
CRNKL1
crooked neck pre-mRNA splicing factor 1
chr12_+_51391273 0.34 ENST00000535225.6
ENST00000358657.7
SLC4A8
solute carrier family 4 member 8
chr7_-_122886706 0.34 ENST00000313070.11
ENST00000334010.11
ENST00000615869.4
CADPS2
calcium dependent secretion activator 2
chr6_+_37005630 0.34 ENST00000274963.13
FGD2
FYVE, RhoGEF and PH domain containing 2
chr21_-_44920918 0.34 ENST00000522688.5
ITGB2
integrin subunit beta 2
chr14_+_65412717 0.34 ENST00000673929.1
FUT8
fucosyltransferase 8
chr9_+_68705230 0.33 ENST00000265382.8
PIP5K1B
phosphatidylinositol-4-phosphate 5-kinase type 1 beta
chr2_-_70553440 0.33 ENST00000450929.5
TGFA
transforming growth factor alpha
chr20_-_47786553 0.33 ENST00000467815.5
ENST00000359930.8
ENST00000484875.5
SULF2
sulfatase 2
chr9_+_68705414 0.33 ENST00000541509.5
PIP5K1B
phosphatidylinositol-4-phosphate 5-kinase type 1 beta
chr22_-_37484505 0.33 ENST00000442496.1
MFNG
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr20_-_3712564 0.32 ENST00000344754.6
SIGLEC1
sialic acid binding Ig like lectin 1
chr12_-_7503744 0.32 ENST00000396620.7
ENST00000432237.3
CD163
CD163 molecule
chr12_-_53507482 0.32 ENST00000267017.4
ENST00000448979.4
NPFF
neuropeptide FF-amide peptide precursor
chr2_+_219597838 0.32 ENST00000456909.6
STK11IP
serine/threonine kinase 11 interacting protein
chr19_-_3786254 0.32 ENST00000585778.5
MATK
megakaryocyte-associated tyrosine kinase
chr17_+_19127535 0.31 ENST00000577213.1
ENST00000344415.9
GRAPL
GRB2 related adaptor protein like
chr9_+_117704382 0.31 ENST00000646089.1
ENST00000355622.8
ENSG00000285082.2
TLR4
novel protein
toll like receptor 4
chr19_-_3786363 0.31 ENST00000310132.11
MATK
megakaryocyte-associated tyrosine kinase
chr19_-_3786408 0.31 ENST00000395040.6
MATK
megakaryocyte-associated tyrosine kinase
chr1_+_209768482 0.31 ENST00000367023.5
TRAF3IP3
TRAF3 interacting protein 3
chr14_+_101761786 0.31 ENST00000422945.6
ENST00000554442.5
ENST00000556260.6
ENST00000328724.9
ENST00000557268.5
PPP2R5C
protein phosphatase 2 regulatory subunit B'gamma
chrX_+_70133433 0.30 ENST00000356413.5
ENST00000342206.10
IGBP1
immunoglobulin binding protein 1
chr1_+_151612001 0.30 ENST00000642376.1
ENST00000368843.8
ENST00000458013.7
SNX27
sorting nexin 27
chr9_-_127778659 0.30 ENST00000314830.13
SH2D3C
SH2 domain containing 3C
chr5_+_65563239 0.30 ENST00000535264.5
ENST00000538977.5
ENST00000261308.10
PPWD1
peptidylprolyl isomerase domain and WD repeat containing 1
chr12_-_7503841 0.30 ENST00000359156.8
CD163
CD163 molecule
chr2_-_191013955 0.29 ENST00000409465.5
STAT1
signal transducer and activator of transcription 1
chr3_-_121660892 0.29 ENST00000428394.6
ENST00000314583.8
HCLS1
hematopoietic cell-specific Lyn substrate 1
chr2_-_151261839 0.28 ENST00000331426.6
RBM43
RNA binding motif protein 43
chr12_-_14961559 0.28 ENST00000228945.9
ENST00000541546.5
ARHGDIB
Rho GDP dissociation inhibitor beta
chr2_+_137964279 0.28 ENST00000329366.8
HNMT
histamine N-methyltransferase
chr12_+_49961864 0.28 ENST00000293599.7
AQP5
aquaporin 5
chr5_-_65563117 0.28 ENST00000508421.5
ENST00000510693.5
ENST00000514814.5
ENST00000396679.6
ENST00000515497.5
CENPK
centromere protein K
chr6_-_24935942 0.28 ENST00000645100.1
ENST00000643898.2
ENST00000613507.4
RIPOR2
RHO family interacting cell polarization regulator 2
chr1_+_22653189 0.27 ENST00000432749.6
C1QB
complement C1q B chain
chr10_+_92831153 0.27 ENST00000672817.1
EXOC6
exocyst complex component 6
chr1_+_161505412 0.27 ENST00000367972.8
FCGR2A
Fc fragment of IgG receptor IIa
chr21_+_33266350 0.27 ENST00000290200.7
IL10RB
interleukin 10 receptor subunit beta
chr6_-_32178080 0.27 ENST00000336984.6
AGPAT1
1-acylglycerol-3-phosphate O-acyltransferase 1
chr10_+_17809337 0.27 ENST00000569591.3
MRC1
mannose receptor C-type 1
chr6_+_130827398 0.26 ENST00000541421.2
SMLR1
small leucine rich protein 1
chr5_+_169637241 0.26 ENST00000520908.7
DOCK2
dedicator of cytokinesis 2
chr9_-_35563867 0.26 ENST00000399742.7
ENST00000619051.4
FAM166B
family with sequence similarity 166 member B
chr2_-_113235443 0.26 ENST00000465084.1
PAX8
paired box 8
chr10_-_73096974 0.26 ENST00000440381.5
ENST00000263556.3
P4HA1
prolyl 4-hydroxylase subunit alpha 1
chr12_+_111405861 0.26 ENST00000341259.7
SH2B3
SH2B adaptor protein 3
chr1_-_30757767 0.26 ENST00000294507.4
LAPTM5
lysosomal protein transmembrane 5
chr6_-_49463173 0.25 ENST00000274813.4
MMUT
methylmalonyl-CoA mutase
chr12_-_121802886 0.25 ENST00000545885.5
ENST00000542933.5
ENST00000428029.6
ENST00000541694.5
ENST00000536662.5
ENST00000535643.5
ENST00000541657.5
LINC01089
RHOF
long intergenic non-protein coding RNA 1089
ras homolog family member F, filopodia associated
chr12_+_25052634 0.25 ENST00000548766.5
IRAG2
inositol 1,4,5-triphosphate receptor associated 2
chr11_+_61333204 0.25 ENST00000532173.6
ENST00000394900.8
TKFC
triokinase and FMN cyclase
chr7_+_106865263 0.24 ENST00000440650.6
ENST00000496166.6
ENST00000473541.5
PIK3CG
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
chr8_+_39913881 0.24 ENST00000518237.6
IDO1
indoleamine 2,3-dioxygenase 1
chr10_-_73096850 0.24 ENST00000307116.6
ENST00000373008.6
ENST00000394890.7
P4HA1
prolyl 4-hydroxylase subunit alpha 1
chr17_-_40937641 0.24 ENST00000209718.8
KRT23
keratin 23
chr2_+_134254065 0.24 ENST00000281923.4
MGAT5
alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase
chr16_-_73048104 0.23 ENST00000268489.10
ZFHX3
zinc finger homeobox 3
chr16_-_30370396 0.23 ENST00000409939.8
TBC1D10B
TBC1 domain family member 10B
chr2_-_42792558 0.23 ENST00000431905.1
ENST00000294973.11
HAAO
3-hydroxyanthranilate 3,4-dioxygenase
chr18_+_13218769 0.23 ENST00000677055.1
ENST00000399848.7
LDLRAD4
low density lipoprotein receptor class A domain containing 4
chr7_+_139829153 0.23 ENST00000652056.1
TBXAS1
thromboxane A synthase 1
chr19_-_41688167 0.23 ENST00000602225.1
CEACAM7
CEA cell adhesion molecule 7
chr11_+_1839602 0.23 ENST00000617947.4
ENST00000252898.11
TNNI2
troponin I2, fast skeletal type
chr6_-_56843638 0.22 ENST00000421834.6
ENST00000370788.6
DST
dystonin
chr9_+_121268060 0.22 ENST00000373808.8
ENST00000432226.7
ENST00000449733.7
GSN
gelsolin
chr10_+_70478761 0.22 ENST00000263563.7
PALD1
phosphatase domain containing paladin 1
chr7_+_141776674 0.22 ENST00000247881.4
TAS2R4
taste 2 receptor member 4
chr7_-_13989891 0.21 ENST00000405218.6
ETV1
ETS variant transcription factor 1
chr18_-_50287570 0.21 ENST00000586837.1
ENST00000412036.6
ENST00000589940.5
ENST00000587396.1
ENST00000591474.5
ENST00000285106.11
CXXC1
CXXC finger protein 1
chrX_+_24054931 0.21 ENST00000253039.9
ENST00000423068.1
EIF2S3
eukaryotic translation initiation factor 2 subunit gamma
chr14_+_44962177 0.20 ENST00000361462.7
ENST00000361577.7
TOGARAM1
TOG array regulator of axonemal microtubules 1
chr4_-_86360071 0.20 ENST00000641677.1
ENST00000639234.1
ENST00000641553.1
ENST00000641826.1
ENST00000641537.1
ENST00000395169.9
ENST00000641408.1
ENST00000638225.1
ENST00000641052.1
MAPK10
mitogen-activated protein kinase 10
chrX_-_47629845 0.20 ENST00000469388.1
ENST00000396992.8
ENST00000377005.6
CFP
complement factor properdin
chr13_+_53028806 0.20 ENST00000219022.3
OLFM4
olfactomedin 4
chr17_-_40937445 0.20 ENST00000436344.7
ENST00000485751.1
KRT23
keratin 23
chr12_+_80716906 0.19 ENST00000228644.4
MYF5
myogenic factor 5
chr14_+_85530127 0.19 ENST00000330753.6
FLRT2
fibronectin leucine rich transmembrane protein 2
chr5_+_160421847 0.19 ENST00000352433.10
ENST00000517480.1
ENST00000520452.5
ENST00000393964.1
PTTG1
PTTG1 regulator of sister chromatid separation, securin
chr5_-_10249876 0.19 ENST00000511437.6
ENST00000280330.12
ENST00000510047.5
ATPSCKMT
ATP synthase c subunit lysine N-methyltransferase
chr18_-_50287816 0.19 ENST00000589548.6
ENST00000673786.1
CXXC1
CXXC finger protein 1
chr2_+_137964446 0.19 ENST00000280096.5
ENST00000280097.5
HNMT
histamine N-methyltransferase
chr16_-_4801301 0.18 ENST00000586504.5
ENST00000649556.1
ROGDI
ENSG00000285952.1
rogdi atypical leucine zipper
novel transcript
chr19_+_35154914 0.18 ENST00000423817.7
FXYD5
FXYD domain containing ion transport regulator 5
chr19_+_16143678 0.18 ENST00000613986.4
ENST00000593031.1
HSH2D
hematopoietic SH2 domain containing
chr6_-_145735964 0.18 ENST00000640980.1
ENST00000639423.1
ENST00000611340.5
EPM2A
EPM2A glucan phosphatase, laforin
chr3_+_32391871 0.18 ENST00000465248.1
CMTM7
CKLF like MARVEL transmembrane domain containing 7
chr9_-_136687380 0.18 ENST00000538402.1
ENST00000371694.7
AGPAT2
1-acylglycerol-3-phosphate O-acyltransferase 2
chr11_-_47378494 0.18 ENST00000533030.1
SPI1
Spi-1 proto-oncogene
chr22_+_41092869 0.18 ENST00000674155.1
EP300
E1A binding protein p300
chr9_+_214843 0.18 ENST00000432829.7
DOCK8
dedicator of cytokinesis 8
chr2_+_147844488 0.18 ENST00000535787.5
ACVR2A
activin A receptor type 2A
chr12_-_54984667 0.17 ENST00000524668.5
ENST00000533607.1
ENST00000449076.6
TESPA1
thymocyte expressed, positive selection associated 1
chr3_-_143848442 0.17 ENST00000474151.1
ENST00000316549.11
SLC9A9
solute carrier family 9 member A9
chr3_-_179266971 0.17 ENST00000349697.2
ENST00000497599.5
KCNMB3
potassium calcium-activated channel subfamily M regulatory beta subunit 3
chr8_-_120445092 0.17 ENST00000518918.1
MRPL13
mitochondrial ribosomal protein L13
chr10_+_11164961 0.17 ENST00000399850.7
ENST00000417956.6
CELF2
CUGBP Elav-like family member 2
chr11_+_1840168 0.17 ENST00000381905.3
TNNI2
troponin I2, fast skeletal type
chrX_-_130165699 0.17 ENST00000676328.1
ENST00000675857.1
ENST00000675427.1
ENST00000675092.1
AIFM1
apoptosis inducing factor mitochondria associated 1
chr7_-_100158679 0.17 ENST00000456769.5
ENST00000316937.8
TRAPPC14
trafficking protein particle complex 14
chr13_-_110561668 0.17 ENST00000267328.5
RAB20
RAB20, member RAS oncogene family
chrX_-_130165825 0.16 ENST00000675240.1
ENST00000319908.8
ENST00000674546.1
ENST00000287295.8
AIFM1
apoptosis inducing factor mitochondria associated 1
chr9_-_136687422 0.16 ENST00000371696.7
AGPAT2
1-acylglycerol-3-phosphate O-acyltransferase 2
chr14_+_101809855 0.16 ENST00000557714.1
ENST00000445439.7
ENST00000334743.9
ENST00000557095.5
PPP2R5C
protein phosphatase 2 regulatory subunit B'gamma
chr18_-_11908330 0.16 ENST00000344987.11
ENST00000588103.5
ENST00000588191.5
ENST00000317235.11
ENST00000309976.13
ENST00000588186.5
ENST00000589267.5
MPPE1
metallophosphoesterase 1
chr17_+_82228397 0.16 ENST00000584689.6
ENST00000392341.6
SLC16A3
solute carrier family 16 member 3

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.9 GO:0045659 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.4 1.3 GO:1902809 regulation of skeletal muscle fiber differentiation(GO:1902809)
0.3 1.3 GO:1903296 regulation of glutamate secretion, neurotransmission(GO:1903294) positive regulation of glutamate secretion, neurotransmission(GO:1903296)
0.3 0.9 GO:1902214 negative regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034125) regulation of interleukin-4-mediated signaling pathway(GO:1902214)
0.2 0.7 GO:0032707 negative regulation of interleukin-23 production(GO:0032707)
0.2 0.7 GO:0036071 N-glycan fucosylation(GO:0036071)
0.2 0.7 GO:0001812 positive regulation of type I hypersensitivity(GO:0001812)
0.2 0.7 GO:0072308 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.2 1.3 GO:0071461 cellular response to redox state(GO:0071461)
0.2 1.2 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.2 0.6 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.2 0.5 GO:0018315 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.2 0.7 GO:0002636 positive regulation of germinal center formation(GO:0002636)
0.1 0.1 GO:1902567 negative regulation of eosinophil activation(GO:1902567)
0.1 0.5 GO:1904045 cellular response to aldosterone(GO:1904045)
0.1 0.6 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.1 1.4 GO:0001955 blood vessel maturation(GO:0001955)
0.1 0.5 GO:2001168 regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.1 0.3 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 0.5 GO:0002277 myeloid dendritic cell activation involved in immune response(GO:0002277)
0.1 0.9 GO:0035986 senescence-associated heterochromatin focus assembly(GO:0035986)
0.1 0.5 GO:0072092 ureteric bud invasion(GO:0072092)
0.1 0.5 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.1 0.5 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.1 1.3 GO:2001300 lipoxin metabolic process(GO:2001300)
0.1 0.1 GO:0001810 regulation of type I hypersensitivity(GO:0001810) type I hypersensitivity(GO:0016068)
0.1 0.3 GO:0039507 modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
0.1 0.5 GO:0001692 histamine metabolic process(GO:0001692)
0.1 0.5 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.1 1.3 GO:2000807 regulation of synaptic vesicle clustering(GO:2000807)
0.1 0.3 GO:0015670 carbon dioxide transport(GO:0015670)
0.1 1.8 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.1 0.4 GO:0061502 early endosome to recycling endosome transport(GO:0061502)
0.1 0.3 GO:0044565 dendritic cell proliferation(GO:0044565)
0.1 0.3 GO:0070253 somatostatin secretion(GO:0070253)
0.1 0.3 GO:2000612 thyroid-stimulating hormone secretion(GO:0070460) regulation of thyroid-stimulating hormone secretion(GO:2000612)
0.1 1.4 GO:0002115 store-operated calcium entry(GO:0002115)
0.1 0.2 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.1 0.2 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.1 0.2 GO:0036269 swimming behavior(GO:0036269)
0.1 0.4 GO:0033625 positive regulation of integrin activation(GO:0033625)
0.1 0.2 GO:1904154 positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.1 0.2 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.1 0.2 GO:0021592 midbrain-hindbrain boundary morphogenesis(GO:0021555) fourth ventricle development(GO:0021592)
0.1 0.3 GO:1903904 negative regulation of establishment of T cell polarity(GO:1903904) negative regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001107)
0.1 1.4 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.1 0.6 GO:0015886 heme transport(GO:0015886)
0.0 0.3 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897) secretory granule localization(GO:0032252)
0.0 0.1 GO:0002238 response to molecule of fungal origin(GO:0002238) cellular response to molecule of fungal origin(GO:0071226)
0.0 0.4 GO:0090481 pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.0 0.1 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.0 0.2 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.2 GO:0001923 B-1 B cell differentiation(GO:0001923) B-1a B cell differentiation(GO:0002337)
0.0 0.2 GO:0044855 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.0 0.3 GO:0001767 establishment of lymphocyte polarity(GO:0001767)
0.0 1.1 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.4 GO:0035973 aggrephagy(GO:0035973)
0.0 0.5 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 0.2 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.2 GO:0034239 macrophage fusion(GO:0034238) regulation of macrophage fusion(GO:0034239) positive regulation of macrophage fusion(GO:0034241)
0.0 0.9 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.0 0.3 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.0 0.5 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.2 GO:0042713 sperm ejaculation(GO:0042713)
0.0 0.3 GO:1990504 dense core granule exocytosis(GO:1990504)
0.0 0.1 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.0 1.1 GO:0051412 response to corticosterone(GO:0051412)
0.0 0.1 GO:0002290 gamma-delta T cell activation involved in immune response(GO:0002290) negative regulation of interferon-beta secretion(GO:0035548) regulation of gamma-delta T cell activation involved in immune response(GO:2001191) positive regulation of gamma-delta T cell activation involved in immune response(GO:2001193)
0.0 0.3 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.0 0.1 GO:1902336 vestibulocochlear nerve structural organization(GO:0021649) neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) positive regulation of retinal ganglion cell axon guidance(GO:1902336) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.0 0.1 GO:0071656 negative regulation of interleukin-3 production(GO:0032712) negative regulation of granulocyte colony-stimulating factor production(GO:0071656) negative regulation of macrophage colony-stimulating factor production(GO:1901257)
0.0 0.1 GO:1905053 regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
0.0 0.2 GO:0051342 regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.0 0.2 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.0 0.2 GO:1901526 positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.0 0.3 GO:0072672 neutrophil extravasation(GO:0072672)
0.0 0.4 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.6 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 1.7 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.1 GO:0018094 protein polyglycylation(GO:0018094)
0.0 0.4 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.1 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.0 0.1 GO:0072086 specification of loop of Henle identity(GO:0072086)
0.0 0.2 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.0 0.1 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.0 0.1 GO:0002194 hepatocyte cell migration(GO:0002194) otic placode formation(GO:0043049) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.0 0.3 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.3 GO:0002087 regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.0 0.2 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902)
0.0 0.2 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.0 0.2 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.3 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.1 GO:0031446 regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448)
0.0 0.6 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.4 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.8 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.0 0.2 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.3 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.2 GO:0090308 regulation of methylation-dependent chromatin silencing(GO:0090308)
0.0 0.1 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.0 0.1 GO:0021707 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.1 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.1 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.0 0.1 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.0 0.1 GO:0042335 cuticle development(GO:0042335)
0.0 0.8 GO:0030225 macrophage differentiation(GO:0030225)
0.0 0.6 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.1 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.0 0.2 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 0.4 GO:0035641 locomotory exploration behavior(GO:0035641)
0.0 0.3 GO:0015669 gas transport(GO:0015669) oxygen transport(GO:0015671)
0.0 0.1 GO:0060753 regulation of mast cell chemotaxis(GO:0060753)
0.0 0.4 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.2 GO:0010990 regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.3 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.2 GO:1904896 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.0 0.1 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.1 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.0 0.1 GO:0072660 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.2 GO:0031642 negative regulation of myelination(GO:0031642)
0.0 0.8 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.1 GO:0061198 fungiform papilla formation(GO:0061198)
0.0 0.1 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.2 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 1.2 GO:0042475 odontogenesis of dentin-containing tooth(GO:0042475)
0.0 0.2 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.0 0.2 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.2 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:0032449 CBM complex(GO:0032449)
0.2 1.3 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.2 0.5 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.1 1.2 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 0.6 GO:0019815 B cell receptor complex(GO:0019815)
0.1 0.9 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.1 0.4 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.1 0.3 GO:0032002 interleukin-28 receptor complex(GO:0032002)
0.1 0.4 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.1 0.7 GO:0032010 phagolysosome(GO:0032010)
0.1 0.9 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.1 0.5 GO:0033503 HULC complex(GO:0033503)
0.1 0.3 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
0.1 1.2 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.3 GO:0031673 H zone(GO:0031673)
0.0 0.1 GO:1990723 cytoplasmic periphery of the nuclear pore complex(GO:1990723)
0.0 0.2 GO:0033263 CORVET complex(GO:0033263)
0.0 0.2 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.2 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.2 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.3 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.0 0.3 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.2 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.1 GO:0031251 PAN complex(GO:0031251)
0.0 0.1 GO:0071159 NF-kappaB complex(GO:0071159)
0.0 0.3 GO:0060171 stereocilium membrane(GO:0060171)
0.0 0.8 GO:0071564 npBAF complex(GO:0071564)
0.0 0.3 GO:0071203 WASH complex(GO:0071203)
0.0 0.4 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.4 GO:0005861 troponin complex(GO:0005861)
0.0 0.3 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 1.0 GO:0001772 immunological synapse(GO:0001772)
0.0 0.2 GO:0030478 actin cap(GO:0030478)
0.0 0.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.0 GO:0001534 radial spoke(GO:0001534)
0.0 0.1 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.2 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.1 GO:0008290 F-actin capping protein complex(GO:0008290)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.3 1.9 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.3 1.3 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.2 0.9 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.2 0.7 GO:0046921 glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
0.2 0.5 GO:0008940 nitrate reductase activity(GO:0008940) molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.2 1.3 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.1 0.4 GO:0052810 1-phosphatidylinositol-5-kinase activity(GO:0052810)
0.1 0.4 GO:0036134 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.1 1.3 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 0.9 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.1 0.4 GO:0045322 unmethylated CpG binding(GO:0045322)
0.1 1.0 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 0.5 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.1 0.3 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1 0.2 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.1 0.6 GO:0070728 leucine binding(GO:0070728)
0.1 0.3 GO:1904492 Ac-Asp-Glu binding(GO:1904492) tetrahydrofolyl-poly(glutamate) polymer binding(GO:1904493)
0.1 0.3 GO:0001626 nociceptin receptor activity(GO:0001626)
0.1 0.3 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.5 GO:0005499 vitamin D binding(GO:0005499)
0.1 0.7 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 0.6 GO:0015232 heme transporter activity(GO:0015232)
0.1 0.3 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.1 0.2 GO:0004339 glucan 1,4-alpha-glucosidase activity(GO:0004339)
0.1 1.6 GO:0071949 FAD binding(GO:0071949)
0.0 0.5 GO:0019864 IgG binding(GO:0019864)
0.0 1.3 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.4 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.9 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.1 GO:0005046 KDEL sequence binding(GO:0005046)
0.0 0.5 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.3 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.0 0.1 GO:0055100 adiponectin binding(GO:0055100)
0.0 0.4 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.5 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.1 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.0 0.1 GO:0030107 HLA-A specific inhibitory MHC class I receptor activity(GO:0030107)
0.0 0.1 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.0 1.7 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.0 0.4 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.3 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.0 0.3 GO:0034235 GPI anchor binding(GO:0034235)
0.0 0.4 GO:0031014 troponin T binding(GO:0031014)
0.0 1.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.3 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.3 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.0 0.2 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.6 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.3 GO:0042608 T cell receptor binding(GO:0042608)
0.0 1.4 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.1 GO:0070735 protein-glycine ligase activity(GO:0070735)
0.0 0.2 GO:0045159 myosin II binding(GO:0045159)
0.0 0.6 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.2 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.0 0.1 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.0 0.1 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.4 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.3 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.0 0.4 GO:0005537 mannose binding(GO:0005537)
0.0 0.6 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.2 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.3 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.1 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.0 0.1 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.2 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.7 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.2 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.3 GO:0015250 water channel activity(GO:0015250)
0.0 0.5 GO:0005123 death receptor binding(GO:0005123)
0.0 0.3 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.2 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.2 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.1 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.1 GO:0000702 oxidized base lesion DNA N-glycosylase activity(GO:0000702)
0.0 0.0 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.0 0.3 GO:0008494 translation activator activity(GO:0008494)
0.0 0.2 GO:0016849 phosphorus-oxygen lyase activity(GO:0016849)
0.0 1.1 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.1 GO:0032357 oxidized purine DNA binding(GO:0032357)
0.0 0.3 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.2 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.4 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.4 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.1 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.3 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.1 GO:0036310 annealing helicase activity(GO:0036310)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 1.1 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.7 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 1.2 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 2.6 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.5 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 1.1 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.6 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.7 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 1.9 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.6 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.1 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 1.8 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.2 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 1.1 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.4 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.6 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.2 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.4 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 1.3 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.5 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.7 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.9 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 0.1 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.6 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.7 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.5 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 1.1 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.3 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.3 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.4 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.2 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.6 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.9 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.4 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing