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Inflammatory response time course, HUVEC (Wada, 2009)
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Results for SPIC
Z-value: 0.87
Motif logo
Transcription factors associated with SPIC
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
SPIC
|
ENSG00000166211.8 | SPIC |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| SPIC | hg38_v1_chr12_+_101475319_101475340 | 0.01 | 9.8e-01 | Click! |
Activity profile of SPIC motif
Sorted Z-values of SPIC motif
Network of associatons between targets according to the STRING database.
First level regulatory network of SPIC
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 2.1 | GO:0045659 | regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659) |
| 0.4 | 1.2 | GO:0072308 | negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308) |
| 0.4 | 2.8 | GO:0018317 | protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406) |
| 0.4 | 2.7 | GO:0000821 | regulation of arginine metabolic process(GO:0000821) |
| 0.4 | 1.8 | GO:1902559 | 3'-phosphoadenosine 5'-phosphosulfate transport(GO:0046963) 3'-phospho-5'-adenylyl sulfate transmembrane transport(GO:1902559) |
| 0.2 | 0.9 | GO:0052148 | modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148) |
| 0.2 | 0.9 | GO:0036058 | filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060) |
| 0.2 | 0.6 | GO:0090285 | negative regulation of protein glycosylation in Golgi(GO:0090285) |
| 0.2 | 0.6 | GO:0032707 | negative regulation of interleukin-23 production(GO:0032707) |
| 0.2 | 1.0 | GO:0044565 | dendritic cell proliferation(GO:0044565) |
| 0.2 | 0.6 | GO:0002316 | follicular B cell differentiation(GO:0002316) |
| 0.2 | 0.4 | GO:0015920 | lipopolysaccharide transport(GO:0015920) |
| 0.2 | 0.8 | GO:0002290 | gamma-delta T cell activation involved in immune response(GO:0002290) negative regulation of interferon-beta secretion(GO:0035548) regulation of gamma-delta T cell activation involved in immune response(GO:2001191) positive regulation of gamma-delta T cell activation involved in immune response(GO:2001193) |
| 0.2 | 1.9 | GO:0045919 | positive regulation of cytolysis(GO:0045919) |
| 0.2 | 0.4 | GO:2001186 | negative regulation of CD8-positive, alpha-beta T cell activation(GO:2001186) |
| 0.2 | 0.5 | GO:0061445 | endocardial cell fate commitment(GO:0060957) endocardial cushion cell fate commitment(GO:0061445) |
| 0.2 | 0.5 | GO:0036071 | N-glycan fucosylation(GO:0036071) |
| 0.1 | 0.4 | GO:0061580 | colon epithelial cell migration(GO:0061580) |
| 0.1 | 0.4 | GO:0007525 | somatic muscle development(GO:0007525) |
| 0.1 | 0.8 | GO:0071461 | cellular response to redox state(GO:0071461) |
| 0.1 | 0.7 | GO:0071051 | polyadenylation-dependent snoRNA 3'-end processing(GO:0071051) |
| 0.1 | 0.1 | GO:1990641 | response to iron ion starvation(GO:1990641) |
| 0.1 | 2.0 | GO:0009313 | oligosaccharide catabolic process(GO:0009313) |
| 0.1 | 0.8 | GO:0050893 | sensory processing(GO:0050893) |
| 0.1 | 1.3 | GO:0002924 | negative regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002924) |
| 0.1 | 0.1 | GO:2000157 | regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157) |
| 0.1 | 0.3 | GO:1903926 | signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926) |
| 0.1 | 0.6 | GO:0032483 | regulation of Rab protein signal transduction(GO:0032483) |
| 0.1 | 0.7 | GO:0016557 | peroxisome membrane biogenesis(GO:0016557) regulation of peroxisome size(GO:0044375) |
| 0.1 | 0.3 | GO:0006447 | regulation of translational initiation by iron(GO:0006447) |
| 0.1 | 0.6 | GO:0071460 | cellular response to cell-matrix adhesion(GO:0071460) |
| 0.1 | 0.4 | GO:1903758 | regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758) |
| 0.1 | 0.3 | GO:0019413 | acetate biosynthetic process(GO:0019413) acetyl-CoA biosynthetic process from acetate(GO:0019427) propionate biosynthetic process(GO:0019542) |
| 0.1 | 0.3 | GO:1902683 | regulation of receptor localization to synapse(GO:1902683) |
| 0.1 | 0.4 | GO:0018076 | N-terminal peptidyl-lysine acetylation(GO:0018076) |
| 0.1 | 0.4 | GO:0036369 | transcription factor catabolic process(GO:0036369) |
| 0.1 | 0.8 | GO:0034472 | snRNA 3'-end processing(GO:0034472) |
| 0.1 | 0.3 | GO:0021569 | rhombomere 3 development(GO:0021569) |
| 0.1 | 0.6 | GO:0010757 | negative regulation of plasminogen activation(GO:0010757) |
| 0.1 | 1.2 | GO:0061179 | negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179) |
| 0.1 | 0.5 | GO:0001692 | histamine metabolic process(GO:0001692) |
| 0.1 | 0.9 | GO:0019367 | fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626) |
| 0.1 | 0.2 | GO:0019541 | propionate metabolic process(GO:0019541) |
| 0.1 | 1.0 | GO:0034058 | endosomal vesicle fusion(GO:0034058) |
| 0.1 | 0.3 | GO:0050904 | diapedesis(GO:0050904) glomerular endothelium development(GO:0072011) |
| 0.1 | 0.2 | GO:0002949 | tRNA threonylcarbamoyladenosine modification(GO:0002949) |
| 0.1 | 1.1 | GO:0043983 | histone H4-K12 acetylation(GO:0043983) |
| 0.1 | 0.8 | GO:0098967 | exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967) |
| 0.1 | 0.4 | GO:0051030 | snRNA transport(GO:0051030) |
| 0.1 | 0.2 | GO:2000646 | positive regulation of receptor catabolic process(GO:2000646) |
| 0.1 | 0.3 | GO:2001166 | regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168) |
| 0.1 | 0.2 | GO:0061571 | dADP phosphorylation(GO:0006174) dGDP phosphorylation(GO:0006186) AMP phosphorylation(GO:0006756) CDP phosphorylation(GO:0061508) dAMP phosphorylation(GO:0061565) CMP phosphorylation(GO:0061566) dCMP phosphorylation(GO:0061567) GDP phosphorylation(GO:0061568) UDP phosphorylation(GO:0061569) dCDP phosphorylation(GO:0061570) TDP phosphorylation(GO:0061571) |
| 0.1 | 0.4 | GO:0071727 | toll-like receptor TLR1:TLR2 signaling pathway(GO:0038123) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727) |
| 0.1 | 0.3 | GO:0036269 | swimming behavior(GO:0036269) |
| 0.1 | 0.3 | GO:0002322 | B cell proliferation involved in immune response(GO:0002322) |
| 0.1 | 0.2 | GO:0018874 | benzoate metabolic process(GO:0018874) |
| 0.1 | 0.3 | GO:1905244 | regulation of modification of synaptic structure(GO:1905244) |
| 0.1 | 0.7 | GO:0048386 | positive regulation of retinoic acid receptor signaling pathway(GO:0048386) |
| 0.1 | 0.6 | GO:0034201 | response to oleic acid(GO:0034201) |
| 0.1 | 0.3 | GO:1903070 | negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070) |
| 0.1 | 1.1 | GO:0006048 | UDP-N-acetylglucosamine biosynthetic process(GO:0006048) |
| 0.1 | 0.3 | GO:2000354 | regulation of ovarian follicle development(GO:2000354) |
| 0.1 | 0.2 | GO:1990637 | response to prolactin(GO:1990637) |
| 0.1 | 0.2 | GO:0072156 | distal tubule morphogenesis(GO:0072156) |
| 0.1 | 0.5 | GO:0097026 | dendritic cell dendrite assembly(GO:0097026) |
| 0.1 | 0.4 | GO:0000255 | allantoin metabolic process(GO:0000255) |
| 0.1 | 0.2 | GO:0043335 | protein unfolding(GO:0043335) |
| 0.1 | 0.3 | GO:0072092 | ureteric bud invasion(GO:0072092) |
| 0.1 | 0.4 | GO:0006710 | androgen catabolic process(GO:0006710) |
| 0.1 | 0.6 | GO:0043152 | induction of bacterial agglutination(GO:0043152) |
| 0.1 | 0.4 | GO:0033211 | adiponectin-activated signaling pathway(GO:0033211) |
| 0.1 | 0.6 | GO:2000389 | regulation of neutrophil extravasation(GO:2000389) |
| 0.0 | 0.4 | GO:0002430 | complement receptor mediated signaling pathway(GO:0002430) |
| 0.0 | 0.3 | GO:0061624 | fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) |
| 0.0 | 1.5 | GO:0043101 | purine-containing compound salvage(GO:0043101) |
| 0.0 | 2.0 | GO:0009435 | NAD biosynthetic process(GO:0009435) |
| 0.0 | 0.1 | GO:0035574 | histone H4-K20 demethylation(GO:0035574) |
| 0.0 | 0.1 | GO:0016108 | tetraterpenoid metabolic process(GO:0016108) carotenoid metabolic process(GO:0016116) carotene catabolic process(GO:0016121) xanthophyll metabolic process(GO:0016122) terpene catabolic process(GO:0046247) |
| 0.0 | 0.3 | GO:0042078 | germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728) |
| 0.0 | 0.1 | GO:1903568 | negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568) |
| 0.0 | 0.4 | GO:0046959 | habituation(GO:0046959) |
| 0.0 | 0.4 | GO:0007598 | blood coagulation, extrinsic pathway(GO:0007598) |
| 0.0 | 0.2 | GO:0046462 | monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651) |
| 0.0 | 0.5 | GO:0007256 | activation of JNKK activity(GO:0007256) |
| 0.0 | 0.4 | GO:2000580 | regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582) |
| 0.0 | 0.3 | GO:0043615 | astrocyte cell migration(GO:0043615) |
| 0.0 | 0.2 | GO:0051795 | embryonic nail plate morphogenesis(GO:0035880) positive regulation of catagen(GO:0051795) activation of meiosis(GO:0090427) |
| 0.0 | 0.9 | GO:0002115 | store-operated calcium entry(GO:0002115) |
| 0.0 | 0.1 | GO:0071529 | cementum mineralization(GO:0071529) |
| 0.0 | 0.2 | GO:0070945 | neutrophil mediated killing of gram-negative bacterium(GO:0070945) |
| 0.0 | 0.1 | GO:0072429 | response to intra-S DNA damage checkpoint signaling(GO:0072429) |
| 0.0 | 0.3 | GO:1901668 | regulation of superoxide dismutase activity(GO:1901668) |
| 0.0 | 0.6 | GO:0002862 | negative regulation of inflammatory response to antigenic stimulus(GO:0002862) |
| 0.0 | 0.6 | GO:0035970 | peptidyl-threonine dephosphorylation(GO:0035970) |
| 0.0 | 0.2 | GO:1900063 | regulation of peroxisome organization(GO:1900063) |
| 0.0 | 0.6 | GO:0045741 | positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) |
| 0.0 | 0.1 | GO:0046947 | hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947) |
| 0.0 | 0.1 | GO:0046349 | amino sugar biosynthetic process(GO:0046349) |
| 0.0 | 0.4 | GO:0006011 | UDP-glucose metabolic process(GO:0006011) |
| 0.0 | 0.1 | GO:0032765 | positive regulation of mast cell cytokine production(GO:0032765) |
| 0.0 | 0.1 | GO:0046338 | phosphatidylethanolamine catabolic process(GO:0046338) |
| 0.0 | 0.1 | GO:0051771 | negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771) |
| 0.0 | 0.4 | GO:0015886 | heme transport(GO:0015886) |
| 0.0 | 0.1 | GO:1903774 | positive regulation of viral budding via host ESCRT complex(GO:1903774) |
| 0.0 | 0.1 | GO:0072425 | signal transduction involved in G2 DNA damage checkpoint(GO:0072425) signal transduction involved in mitotic G2 DNA damage checkpoint(GO:0072434) |
| 0.0 | 0.5 | GO:0071372 | cellular response to follicle-stimulating hormone stimulus(GO:0071372) |
| 0.0 | 0.1 | GO:0048627 | myoblast development(GO:0048627) |
| 0.0 | 0.1 | GO:0036265 | RNA (guanine-N7)-methylation(GO:0036265) rRNA (guanine-N7)-methylation(GO:0070476) |
| 0.0 | 0.5 | GO:0006020 | inositol metabolic process(GO:0006020) |
| 0.0 | 0.5 | GO:0002315 | marginal zone B cell differentiation(GO:0002315) |
| 0.0 | 0.3 | GO:0034723 | DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723) |
| 0.0 | 0.2 | GO:0014057 | positive regulation of acetylcholine secretion, neurotransmission(GO:0014057) |
| 0.0 | 0.1 | GO:0071449 | cellular response to lipid hydroperoxide(GO:0071449) |
| 0.0 | 0.1 | GO:0035022 | positive regulation of Rac protein signal transduction(GO:0035022) |
| 0.0 | 0.4 | GO:0061469 | regulation of type B pancreatic cell proliferation(GO:0061469) |
| 0.0 | 0.5 | GO:1902018 | negative regulation of cilium assembly(GO:1902018) |
| 0.0 | 0.2 | GO:0016139 | glycoside catabolic process(GO:0016139) |
| 0.0 | 0.7 | GO:0044849 | estrous cycle(GO:0044849) |
| 0.0 | 0.4 | GO:0071285 | cellular response to lithium ion(GO:0071285) |
| 0.0 | 0.1 | GO:0016259 | selenocysteine metabolic process(GO:0016259) |
| 0.0 | 0.1 | GO:0060010 | Sertoli cell fate commitment(GO:0060010) |
| 0.0 | 0.2 | GO:0098789 | pre-mRNA cleavage required for polyadenylation(GO:0098789) |
| 0.0 | 0.4 | GO:0021859 | pyramidal neuron differentiation(GO:0021859) |
| 0.0 | 0.3 | GO:0061299 | retina vasculature morphogenesis in camera-type eye(GO:0061299) |
| 0.0 | 0.4 | GO:0016558 | protein import into peroxisome matrix(GO:0016558) |
| 0.0 | 0.0 | GO:0035359 | negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359) |
| 0.0 | 0.1 | GO:0042989 | sequestering of actin monomers(GO:0042989) |
| 0.0 | 0.1 | GO:0006127 | glycerophosphate shuttle(GO:0006127) |
| 0.0 | 0.1 | GO:0051311 | meiotic metaphase I plate congression(GO:0043060) meiotic spindle midzone assembly(GO:0051257) meiotic metaphase plate congression(GO:0051311) |
| 0.0 | 0.2 | GO:1904885 | beta-catenin destruction complex assembly(GO:1904885) |
| 0.0 | 0.1 | GO:1904219 | regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222) |
| 0.0 | 0.0 | GO:1900227 | positive regulation of NLRP3 inflammasome complex assembly(GO:1900227) |
| 0.0 | 0.1 | GO:0045079 | negative regulation of chemokine biosynthetic process(GO:0045079) |
| 0.0 | 0.3 | GO:1901727 | positive regulation of histone deacetylase activity(GO:1901727) |
| 0.0 | 0.1 | GO:0051344 | negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344) |
| 0.0 | 0.2 | GO:0071569 | protein ufmylation(GO:0071569) |
| 0.0 | 0.1 | GO:0048633 | positive regulation of skeletal muscle tissue growth(GO:0048633) |
| 0.0 | 0.2 | GO:0009249 | protein lipoylation(GO:0009249) |
| 0.0 | 0.1 | GO:0044313 | protein K6-linked deubiquitination(GO:0044313) |
| 0.0 | 0.4 | GO:0034656 | nucleobase-containing small molecule catabolic process(GO:0034656) |
| 0.0 | 0.8 | GO:0051482 | positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482) |
| 0.0 | 0.8 | GO:0071577 | zinc II ion transmembrane transport(GO:0071577) |
| 0.0 | 0.4 | GO:0002003 | angiotensin maturation(GO:0002003) |
| 0.0 | 0.2 | GO:0072662 | protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663) |
| 0.0 | 0.2 | GO:0035609 | C-terminal protein deglutamylation(GO:0035609) |
| 0.0 | 0.5 | GO:0035728 | response to hepatocyte growth factor(GO:0035728) |
| 0.0 | 0.1 | GO:0072672 | negative regulation of triglyceride catabolic process(GO:0010897) neutrophil extravasation(GO:0072672) |
| 0.0 | 0.2 | GO:0006348 | chromatin silencing at telomere(GO:0006348) |
| 0.0 | 0.1 | GO:0035063 | nuclear speck organization(GO:0035063) |
| 0.0 | 0.1 | GO:0090135 | actin filament branching(GO:0090135) protein localization to cell leading edge(GO:1902463) |
| 0.0 | 0.1 | GO:1904694 | negative regulation of vascular smooth muscle contraction(GO:1904694) |
| 0.0 | 0.8 | GO:0006506 | GPI anchor metabolic process(GO:0006505) GPI anchor biosynthetic process(GO:0006506) |
| 0.0 | 0.2 | GO:0006477 | protein sulfation(GO:0006477) |
| 0.0 | 0.2 | GO:0000712 | resolution of meiotic recombination intermediates(GO:0000712) |
| 0.0 | 0.1 | GO:0002329 | pre-B cell differentiation(GO:0002329) |
| 0.0 | 0.1 | GO:0001955 | blood vessel maturation(GO:0001955) |
| 0.0 | 0.2 | GO:0031642 | negative regulation of myelination(GO:0031642) |
| 0.0 | 0.2 | GO:0061298 | retina vasculature development in camera-type eye(GO:0061298) |
| 0.0 | 0.9 | GO:0031572 | G2 DNA damage checkpoint(GO:0031572) |
| 0.0 | 0.2 | GO:1901409 | positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409) |
| 0.0 | 0.1 | GO:0070172 | positive regulation of tooth mineralization(GO:0070172) |
| 0.0 | 0.2 | GO:1901223 | negative regulation of NIK/NF-kappaB signaling(GO:1901223) |
| 0.0 | 0.1 | GO:0006682 | galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375) |
| 0.0 | 0.4 | GO:0035518 | histone H2A monoubiquitination(GO:0035518) |
| 0.0 | 0.2 | GO:0035878 | nail development(GO:0035878) |
| 0.0 | 2.1 | GO:0006958 | complement activation, classical pathway(GO:0006958) |
| 0.0 | 0.3 | GO:0034498 | early endosome to Golgi transport(GO:0034498) |
| 0.0 | 0.5 | GO:0007202 | activation of phospholipase C activity(GO:0007202) |
| 0.0 | 0.2 | GO:0061029 | eyelid development in camera-type eye(GO:0061029) |
| 0.0 | 0.5 | GO:0060716 | labyrinthine layer blood vessel development(GO:0060716) |
| 0.0 | 0.1 | GO:0070236 | negative regulation of activation-induced cell death of T cells(GO:0070236) |
| 0.0 | 0.0 | GO:0031125 | rRNA 3'-end processing(GO:0031125) |
| 0.0 | 0.2 | GO:0006995 | cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562) |
| 0.0 | 0.4 | GO:0030208 | dermatan sulfate biosynthetic process(GO:0030208) |
| 0.0 | 0.3 | GO:0016024 | CDP-diacylglycerol biosynthetic process(GO:0016024) |
| 0.0 | 0.7 | GO:0006376 | mRNA splice site selection(GO:0006376) |
| 0.0 | 0.3 | GO:0042953 | lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872) |
| 0.0 | 0.4 | GO:0000732 | strand displacement(GO:0000732) |
| 0.0 | 0.3 | GO:0071157 | negative regulation of cell cycle arrest(GO:0071157) |
| 0.0 | 0.2 | GO:0034447 | very-low-density lipoprotein particle clearance(GO:0034447) |
| 0.0 | 0.4 | GO:0071801 | regulation of podosome assembly(GO:0071801) |
| 0.0 | 0.0 | GO:0030974 | thiamine pyrophosphate transport(GO:0030974) |
| 0.0 | 0.1 | GO:0003433 | chondrocyte development involved in endochondral bone morphogenesis(GO:0003433) |
| 0.0 | 0.2 | GO:0046321 | positive regulation of fatty acid oxidation(GO:0046321) |
| 0.0 | 0.3 | GO:0006590 | thyroid hormone generation(GO:0006590) |
| 0.0 | 0.1 | GO:0071763 | nuclear membrane organization(GO:0071763) |
| 0.0 | 0.4 | GO:0009081 | branched-chain amino acid metabolic process(GO:0009081) |
| 0.0 | 0.0 | GO:0034427 | nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427) |
| 0.0 | 0.3 | GO:0007141 | male meiosis I(GO:0007141) |
| 0.0 | 0.1 | GO:0006703 | estrogen biosynthetic process(GO:0006703) |
| 0.0 | 0.3 | GO:0006266 | DNA ligation(GO:0006266) |
| 0.0 | 0.1 | GO:0001957 | intramembranous ossification(GO:0001957) direct ossification(GO:0036072) |
| 0.0 | 0.1 | GO:0010606 | positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606) |
| 0.0 | 0.0 | GO:1900228 | biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229) |
| 0.0 | 0.5 | GO:0015721 | bile acid and bile salt transport(GO:0015721) |
| 0.0 | 0.2 | GO:0010457 | centriole-centriole cohesion(GO:0010457) |
| 0.0 | 0.1 | GO:0006269 | DNA replication, synthesis of RNA primer(GO:0006269) |
| 0.0 | 0.2 | GO:1904380 | endoplasmic reticulum mannose trimming(GO:1904380) |
| 0.0 | 0.1 | GO:0051533 | positive regulation of NFAT protein import into nucleus(GO:0051533) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 1.5 | GO:1902560 | GMP reductase complex(GO:1902560) |
| 0.2 | 0.9 | GO:0033263 | CORVET complex(GO:0033263) |
| 0.2 | 0.6 | GO:0005602 | complement component C1 complex(GO:0005602) |
| 0.2 | 0.8 | GO:1990796 | photoreceptor cell terminal bouton(GO:1990796) |
| 0.1 | 0.4 | GO:0070195 | growth hormone receptor complex(GO:0070195) |
| 0.1 | 0.5 | GO:0097123 | cyclin A1-CDK2 complex(GO:0097123) |
| 0.1 | 1.1 | GO:0046696 | lipopolysaccharide receptor complex(GO:0046696) |
| 0.1 | 0.5 | GO:0048179 | activin receptor complex(GO:0048179) |
| 0.1 | 0.4 | GO:1990876 | cytoplasmic side of nuclear pore(GO:1990876) |
| 0.1 | 0.3 | GO:0032002 | interleukin-28 receptor complex(GO:0032002) |
| 0.1 | 0.4 | GO:0032807 | DNA ligase IV complex(GO:0032807) |
| 0.1 | 0.6 | GO:0005797 | Golgi medial cisterna(GO:0005797) |
| 0.1 | 0.8 | GO:0042105 | alpha-beta T cell receptor complex(GO:0042105) |
| 0.1 | 0.4 | GO:0005947 | mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) |
| 0.1 | 0.4 | GO:1990357 | terminal web(GO:1990357) |
| 0.1 | 0.3 | GO:0043625 | delta DNA polymerase complex(GO:0043625) |
| 0.1 | 0.8 | GO:0034464 | BBSome(GO:0034464) |
| 0.1 | 0.6 | GO:0097470 | ribbon synapse(GO:0097470) |
| 0.1 | 0.4 | GO:1990726 | Lsm1-7-Pat1 complex(GO:1990726) |
| 0.1 | 0.6 | GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex(GO:0031465) |
| 0.1 | 0.2 | GO:0071821 | FANCM-MHF complex(GO:0071821) |
| 0.1 | 0.2 | GO:0071920 | cleavage body(GO:0071920) |
| 0.0 | 0.7 | GO:0000176 | nuclear exosome (RNase complex)(GO:0000176) |
| 0.0 | 0.3 | GO:0071012 | catalytic step 1 spliceosome(GO:0071012) |
| 0.0 | 0.3 | GO:0098837 | postsynaptic recycling endosome(GO:0098837) |
| 0.0 | 0.3 | GO:0030485 | smooth muscle contractile fiber(GO:0030485) |
| 0.0 | 0.6 | GO:0042589 | zymogen granule membrane(GO:0042589) |
| 0.0 | 0.5 | GO:0016593 | Cdc73/Paf1 complex(GO:0016593) |
| 0.0 | 0.3 | GO:0033503 | HULC complex(GO:0033503) |
| 0.0 | 0.6 | GO:0032039 | integrator complex(GO:0032039) |
| 0.0 | 0.2 | GO:0071817 | MMXD complex(GO:0071817) |
| 0.0 | 0.3 | GO:1990130 | Iml1 complex(GO:1990130) |
| 0.0 | 0.5 | GO:0032797 | SMN complex(GO:0032797) |
| 0.0 | 0.1 | GO:0031251 | PAN complex(GO:0031251) |
| 0.0 | 0.4 | GO:0072357 | PTW/PP1 phosphatase complex(GO:0072357) |
| 0.0 | 0.2 | GO:0000408 | EKC/KEOPS complex(GO:0000408) |
| 0.0 | 0.4 | GO:0097197 | tetraspanin-enriched microdomain(GO:0097197) |
| 0.0 | 0.3 | GO:0005683 | U7 snRNP(GO:0005683) |
| 0.0 | 0.7 | GO:0031265 | CD95 death-inducing signaling complex(GO:0031265) |
| 0.0 | 0.1 | GO:0070939 | Dsl1p complex(GO:0070939) |
| 0.0 | 0.8 | GO:0030877 | beta-catenin destruction complex(GO:0030877) |
| 0.0 | 3.2 | GO:0005637 | nuclear inner membrane(GO:0005637) |
| 0.0 | 0.2 | GO:0019815 | B cell receptor complex(GO:0019815) |
| 0.0 | 0.2 | GO:0000172 | ribonuclease MRP complex(GO:0000172) |
| 0.0 | 0.2 | GO:0042587 | glycogen granule(GO:0042587) |
| 0.0 | 1.7 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
| 0.0 | 0.2 | GO:0070033 | synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) |
| 0.0 | 0.5 | GO:0033276 | transcription factor TFTC complex(GO:0033276) |
| 0.0 | 2.3 | GO:0035577 | azurophil granule membrane(GO:0035577) |
| 0.0 | 0.4 | GO:0017119 | Golgi transport complex(GO:0017119) |
| 0.0 | 0.1 | GO:0048476 | Holliday junction resolvase complex(GO:0048476) |
| 0.0 | 0.3 | GO:0033018 | sarcoplasmic reticulum lumen(GO:0033018) |
| 0.0 | 0.1 | GO:0030289 | protein phosphatase 4 complex(GO:0030289) |
| 0.0 | 0.1 | GO:0005715 | late recombination nodule(GO:0005715) |
| 0.0 | 0.7 | GO:0031231 | integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231) |
| 0.0 | 0.2 | GO:0098554 | cytoplasmic side of endoplasmic reticulum membrane(GO:0098554) |
| 0.0 | 0.3 | GO:0019774 | proteasome core complex, beta-subunit complex(GO:0019774) |
| 0.0 | 0.5 | GO:0000145 | exocyst(GO:0000145) |
| 0.0 | 0.1 | GO:0009331 | glycerol-3-phosphate dehydrogenase complex(GO:0009331) |
| 0.0 | 0.1 | GO:0031228 | intrinsic component of Golgi membrane(GO:0031228) |
| 0.0 | 1.5 | GO:0045095 | keratin filament(GO:0045095) |
| 0.0 | 0.2 | GO:0070552 | BRISC complex(GO:0070552) |
| 0.0 | 0.3 | GO:0031254 | uropod(GO:0001931) cell trailing edge(GO:0031254) |
| 0.0 | 1.2 | GO:0031903 | peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903) |
| 0.0 | 0.1 | GO:0030121 | AP-1 adaptor complex(GO:0030121) |
| 0.0 | 0.1 | GO:0045179 | apical cortex(GO:0045179) |
| 0.0 | 0.1 | GO:0042765 | GPI-anchor transamidase complex(GO:0042765) |
| 0.0 | 0.1 | GO:0043527 | tRNA methyltransferase complex(GO:0043527) |
| 0.0 | 0.1 | GO:0034751 | aryl hydrocarbon receptor complex(GO:0034751) |
| 0.0 | 0.4 | GO:0031528 | microvillus membrane(GO:0031528) |
| 0.0 | 0.0 | GO:0005953 | CAAX-protein geranylgeranyltransferase complex(GO:0005953) |
| 0.0 | 0.9 | GO:0002102 | podosome(GO:0002102) |
| 0.0 | 0.2 | GO:0030008 | TRAPP complex(GO:0030008) |
| 0.0 | 0.1 | GO:0065010 | extracellular membrane-bounded organelle(GO:0065010) |
| 0.0 | 1.9 | GO:0005766 | primary lysosome(GO:0005766) azurophil granule(GO:0042582) |
| 0.0 | 0.4 | GO:0044322 | endoplasmic reticulum quality control compartment(GO:0044322) |
| 0.0 | 0.3 | GO:0034362 | low-density lipoprotein particle(GO:0034362) |
| 0.0 | 0.6 | GO:0099738 | cell cortex region(GO:0099738) |
| 0.0 | 0.1 | GO:0005658 | alpha DNA polymerase:primase complex(GO:0005658) |
| 0.0 | 0.4 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 1.9 | GO:0061769 | ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769) |
| 0.4 | 1.8 | GO:0046964 | 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964) |
| 0.3 | 2.1 | GO:0016314 | phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314) |
| 0.3 | 1.5 | GO:0003920 | GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657) |
| 0.3 | 1.2 | GO:0042282 | hydroxymethylglutaryl-CoA reductase (NADPH) activity(GO:0004420) hydroxymethylglutaryl-CoA reductase activity(GO:0042282) |
| 0.2 | 0.6 | GO:0035375 | zymogen binding(GO:0035375) |
| 0.2 | 0.8 | GO:0030107 | HLA-A specific inhibitory MHC class I receptor activity(GO:0030107) |
| 0.2 | 0.5 | GO:0071209 | U7 snRNA binding(GO:0071209) |
| 0.2 | 0.5 | GO:0004421 | hydroxymethylglutaryl-CoA synthase activity(GO:0004421) |
| 0.2 | 2.7 | GO:0015174 | basic amino acid transmembrane transporter activity(GO:0015174) |
| 0.2 | 0.9 | GO:0097199 | cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199) |
| 0.2 | 0.5 | GO:0046921 | glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921) |
| 0.2 | 0.5 | GO:0000252 | C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity(GO:0000252) sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity(GO:0047012) |
| 0.1 | 0.4 | GO:0003863 | alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863) |
| 0.1 | 0.6 | GO:0033829 | O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829) |
| 0.1 | 1.0 | GO:0001875 | lipopolysaccharide receptor activity(GO:0001875) |
| 0.1 | 0.9 | GO:0004873 | asialoglycoprotein receptor activity(GO:0004873) |
| 0.1 | 0.4 | GO:0055100 | adiponectin binding(GO:0055100) |
| 0.1 | 2.0 | GO:0015923 | mannosidase activity(GO:0015923) |
| 0.1 | 0.7 | GO:0004966 | galanin receptor activity(GO:0004966) |
| 0.1 | 1.1 | GO:0070569 | uridylyltransferase activity(GO:0070569) |
| 0.1 | 0.4 | GO:0003943 | N-acetylgalactosamine-4-sulfatase activity(GO:0003943) |
| 0.1 | 0.5 | GO:0033857 | diphosphoinositol-pentakisphosphate kinase activity(GO:0033857) |
| 0.1 | 0.4 | GO:0061628 | H3K27me3 modified histone binding(GO:0061628) |
| 0.1 | 0.8 | GO:0017040 | ceramidase activity(GO:0017040) |
| 0.1 | 0.3 | GO:0004314 | [acyl-carrier-protein] S-malonyltransferase activity(GO:0004314) 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315) S-malonyltransferase activity(GO:0016419) malonyltransferase activity(GO:0016420) |
| 0.1 | 0.5 | GO:0008508 | bile acid:sodium symporter activity(GO:0008508) |
| 0.1 | 0.4 | GO:0047757 | chondroitin-glucuronate 5-epimerase activity(GO:0047757) |
| 0.1 | 0.3 | GO:0033754 | indoleamine 2,3-dioxygenase activity(GO:0033754) |
| 0.1 | 2.8 | GO:0000030 | mannosyltransferase activity(GO:0000030) |
| 0.1 | 0.6 | GO:0043141 | ATP-dependent 5'-3' DNA helicase activity(GO:0043141) |
| 0.1 | 0.9 | GO:0102337 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
| 0.1 | 0.6 | GO:0016618 | hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267) |
| 0.1 | 0.5 | GO:0016361 | activin receptor activity, type I(GO:0016361) |
| 0.1 | 0.8 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
| 0.1 | 0.9 | GO:0015279 | store-operated calcium channel activity(GO:0015279) |
| 0.1 | 0.6 | GO:0034235 | GPI anchor binding(GO:0034235) |
| 0.1 | 0.8 | GO:0047760 | butyrate-CoA ligase activity(GO:0047760) |
| 0.1 | 0.3 | GO:0003987 | acetate-CoA ligase activity(GO:0003987) |
| 0.1 | 0.3 | GO:0017159 | pantetheine hydrolase activity(GO:0017159) |
| 0.1 | 0.6 | GO:0046703 | natural killer cell lectin-like receptor binding(GO:0046703) |
| 0.1 | 0.5 | GO:0004468 | lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468) |
| 0.1 | 0.3 | GO:0070573 | metallodipeptidase activity(GO:0070573) |
| 0.1 | 0.4 | GO:0016019 | peptidoglycan receptor activity(GO:0016019) |
| 0.1 | 1.7 | GO:0005001 | transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198) |
| 0.1 | 1.1 | GO:0001087 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087) |
| 0.0 | 0.1 | GO:0035575 | histone demethylase activity (H4-K20 specific)(GO:0035575) |
| 0.0 | 0.3 | GO:0004920 | interleukin-10 receptor activity(GO:0004920) |
| 0.0 | 0.3 | GO:0004694 | eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694) |
| 0.0 | 0.1 | GO:0047006 | 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006) |
| 0.0 | 0.4 | GO:0035251 | UDP-glucosyltransferase activity(GO:0035251) |
| 0.0 | 0.2 | GO:1904492 | Ac-Asp-Glu binding(GO:1904492) tetrahydrofolyl-poly(glutamate) polymer binding(GO:1904493) |
| 0.0 | 0.8 | GO:0034452 | dynactin binding(GO:0034452) |
| 0.0 | 0.4 | GO:0004875 | complement receptor activity(GO:0004875) |
| 0.0 | 0.3 | GO:1904288 | BAT3 complex binding(GO:1904288) |
| 0.0 | 0.1 | GO:0008475 | procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823) |
| 0.0 | 0.1 | GO:0032089 | NACHT domain binding(GO:0032089) |
| 0.0 | 0.4 | GO:0015232 | heme transporter activity(GO:0015232) |
| 0.0 | 0.4 | GO:0004303 | estradiol 17-beta-dehydrogenase activity(GO:0004303) |
| 0.0 | 0.2 | GO:0016812 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812) |
| 0.0 | 0.6 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
| 0.0 | 0.6 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) |
| 0.0 | 0.2 | GO:0043812 | phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812) |
| 0.0 | 0.2 | GO:0008889 | glycerophosphodiester phosphodiesterase activity(GO:0008889) |
| 0.0 | 0.1 | GO:0052591 | sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591) |
| 0.0 | 0.2 | GO:0004045 | aminoacyl-tRNA hydrolase activity(GO:0004045) |
| 0.0 | 0.4 | GO:0039706 | co-receptor binding(GO:0039706) |
| 0.0 | 0.2 | GO:0004366 | glycerol-3-phosphate O-acyltransferase activity(GO:0004366) |
| 0.0 | 0.3 | GO:0050291 | sphingosine N-acyltransferase activity(GO:0050291) |
| 0.0 | 1.3 | GO:0000983 | transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983) |
| 0.0 | 0.1 | GO:0019770 | IgG receptor activity(GO:0019770) |
| 0.0 | 0.2 | GO:0070290 | N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290) |
| 0.0 | 0.3 | GO:0045504 | dynein heavy chain binding(GO:0045504) |
| 0.0 | 1.3 | GO:0005484 | SNAP receptor activity(GO:0005484) |
| 0.0 | 0.1 | GO:0042954 | lipoprotein transporter activity(GO:0042954) |
| 0.0 | 0.4 | GO:0017110 | nucleoside-diphosphatase activity(GO:0017110) |
| 0.0 | 0.2 | GO:0001517 | N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) |
| 0.0 | 0.3 | GO:0071933 | Arp2/3 complex binding(GO:0071933) |
| 0.0 | 0.2 | GO:0034485 | phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485) phosphatidylinositol trisphosphate phosphatase activity(GO:0034594) |
| 0.0 | 0.2 | GO:0004064 | arylesterase activity(GO:0004064) |
| 0.0 | 0.8 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
| 0.0 | 0.2 | GO:0070700 | BMP receptor binding(GO:0070700) |
| 0.0 | 0.1 | GO:0016435 | rRNA (guanine) methyltransferase activity(GO:0016435) |
| 0.0 | 0.2 | GO:0030229 | very-low-density lipoprotein particle receptor activity(GO:0030229) |
| 0.0 | 0.2 | GO:0050145 | nucleoside phosphate kinase activity(GO:0050145) |
| 0.0 | 0.5 | GO:0019992 | diacylglycerol binding(GO:0019992) |
| 0.0 | 0.1 | GO:0004040 | amidase activity(GO:0004040) |
| 0.0 | 0.1 | GO:0090541 | MIT domain binding(GO:0090541) |
| 0.0 | 0.1 | GO:0003923 | GPI-anchor transamidase activity(GO:0003923) |
| 0.0 | 0.6 | GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) |
| 0.0 | 1.1 | GO:0016831 | carboxy-lyase activity(GO:0016831) |
| 0.0 | 1.1 | GO:0004180 | carboxypeptidase activity(GO:0004180) |
| 0.0 | 0.4 | GO:0000339 | RNA cap binding(GO:0000339) |
| 0.0 | 0.1 | GO:0004035 | alkaline phosphatase activity(GO:0004035) |
| 0.0 | 0.1 | GO:0016936 | galactoside binding(GO:0016936) |
| 0.0 | 0.1 | GO:0070051 | fibrinogen binding(GO:0070051) |
| 0.0 | 1.5 | GO:0035064 | methylated histone binding(GO:0035064) |
| 0.0 | 0.4 | GO:0043422 | protein kinase B binding(GO:0043422) |
| 0.0 | 0.7 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
| 0.0 | 0.2 | GO:0004526 | ribonuclease P activity(GO:0004526) |
| 0.0 | 0.5 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
| 0.0 | 0.1 | GO:0043426 | MRF binding(GO:0043426) |
| 0.0 | 0.2 | GO:1904264 | ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264) |
| 0.0 | 0.2 | GO:0001206 | transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206) |
| 0.0 | 0.2 | GO:0031802 | type 5 metabotropic glutamate receptor binding(GO:0031802) |
| 0.0 | 0.2 | GO:0031386 | protein tag(GO:0031386) |
| 0.0 | 0.0 | GO:0004662 | CAAX-protein geranylgeranyltransferase activity(GO:0004662) |
| 0.0 | 0.1 | GO:0017060 | 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060) |
| 0.0 | 0.2 | GO:0097371 | MDM2/MDM4 family protein binding(GO:0097371) |
| 0.0 | 0.0 | GO:0033699 | DNA 5'-adenosine monophosphate hydrolase activity(GO:0033699) |
| 0.0 | 0.6 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
| 0.0 | 0.0 | GO:0090422 | thiamine pyrophosphate transporter activity(GO:0090422) |
| 0.0 | 0.5 | GO:0004435 | phosphatidylinositol phospholipase C activity(GO:0004435) |
| 0.0 | 0.1 | GO:0016174 | NAD(P)H oxidase activity(GO:0016174) |
| 0.0 | 0.5 | GO:0017091 | AU-rich element binding(GO:0017091) |
| 0.0 | 0.4 | GO:0070064 | proline-rich region binding(GO:0070064) |
| 0.0 | 0.1 | GO:0047134 | protein-disulfide reductase activity(GO:0047134) |
| 0.0 | 0.8 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
| 0.0 | 0.2 | GO:0015379 | potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820) |
| 0.0 | 0.2 | GO:0005049 | nuclear export signal receptor activity(GO:0005049) |
| 0.0 | 0.1 | GO:0008821 | crossover junction endodeoxyribonuclease activity(GO:0008821) |
| 0.0 | 0.2 | GO:0008271 | secondary active sulfate transmembrane transporter activity(GO:0008271) |
| 0.0 | 0.0 | GO:0000035 | acyl binding(GO:0000035) |
| 0.0 | 0.1 | GO:0047499 | calcium-independent phospholipase A2 activity(GO:0047499) |
| 0.0 | 0.1 | GO:0005221 | intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855) |
| 0.0 | 0.1 | GO:0042799 | histone methyltransferase activity (H4-K20 specific)(GO:0042799) |
| 0.0 | 0.1 | GO:0032137 | guanine/thymine mispair binding(GO:0032137) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.2 | ST TYPE I INTERFERON PATHWAY | Type I Interferon (alpha/beta IFN) Pathway |
| 0.1 | 0.8 | ST PAC1 RECEPTOR PATHWAY | PAC1 Receptor Pathway |
| 0.0 | 2.0 | ST INTERLEUKIN 4 PATHWAY | Interleukin 4 (IL-4) Pathway |
| 0.0 | 0.3 | PID BCR 5PATHWAY | BCR signaling pathway |
| 0.0 | 0.5 | PID ALK2 PATHWAY | ALK2 signaling events |
| 0.0 | 1.0 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
| 0.0 | 0.5 | SA REG CASCADE OF CYCLIN EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
| 0.0 | 1.7 | PID AJDISS 2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
| 0.0 | 0.6 | SA FAS SIGNALING | The TNF-type receptor Fas induces apoptosis on ligand binding. |
| 0.0 | 1.1 | PID HIF2PATHWAY | HIF-2-alpha transcription factor network |
| 0.0 | 0.3 | PID HDAC CLASSIII PATHWAY | Signaling events mediated by HDAC Class III |
| 0.0 | 1.0 | SIG PIP3 SIGNALING IN B LYMPHOCYTES | Genes related to PIP3 signaling in B lymphocytes |
| 0.0 | 0.8 | PID MYC PATHWAY | C-MYC pathway |
| 0.0 | 0.5 | PID DNA PK PATHWAY | DNA-PK pathway in nonhomologous end joining |
| 0.0 | 0.4 | PID SMAD2 3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
| 0.0 | 0.9 | PID CDC42 REG PATHWAY | Regulation of CDC42 activity |
| 0.0 | 0.1 | PID P38 MK2 PATHWAY | p38 signaling mediated by MAPKAP kinases |
| 0.0 | 0.2 | PID ARF6 DOWNSTREAM PATHWAY | Arf6 downstream pathway |
| 0.0 | 0.1 | PID BARD1 PATHWAY | BARD1 signaling events |
| 0.0 | 0.6 | PID RAS PATHWAY | Regulation of Ras family activation |
| 0.0 | 1.2 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
| 0.0 | 0.3 | PID RB 1PATHWAY | Regulation of retinoblastoma protein |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.1 | REACTOME ADP SIGNALLING THROUGH P2RY12 | Genes involved in ADP signalling through P2Y purinoceptor 12 |
| 0.1 | 2.2 | REACTOME REGULATION OF IFNG SIGNALING | Genes involved in Regulation of IFNG signaling |
| 0.1 | 1.0 | REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 | Genes involved in IKK complex recruitment mediated by RIP1 |
| 0.1 | 1.5 | REACTOME PURINE SALVAGE | Genes involved in Purine salvage |
| 0.1 | 2.2 | REACTOME CHOLESTEROL BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
| 0.1 | 0.7 | REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE | Genes involved in mRNA Decay by 3' to 5' Exoribonuclease |
| 0.0 | 0.6 | REACTOME CREATION OF C4 AND C2 ACTIVATORS | Genes involved in Creation of C4 and C2 activators |
| 0.0 | 2.5 | REACTOME BASIGIN INTERACTIONS | Genes involved in Basigin interactions |
| 0.0 | 1.3 | REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS | Genes involved in Proteolytic cleavage of SNARE complex proteins |
| 0.0 | 0.9 | REACTOME REGULATION OF COMPLEMENT CASCADE | Genes involved in Regulation of Complement cascade |
| 0.0 | 0.4 | REACTOME TRYPTOPHAN CATABOLISM | Genes involved in Tryptophan catabolism |
| 0.0 | 1.2 | REACTOME FATTY ACYL COA BIOSYNTHESIS | Genes involved in Fatty Acyl-CoA Biosynthesis |
| 0.0 | 0.4 | REACTOME ABACAVIR TRANSPORT AND METABOLISM | Genes involved in Abacavir transport and metabolism |
| 0.0 | 0.4 | REACTOME INTEGRATION OF PROVIRUS | Genes involved in Integration of provirus |
| 0.0 | 0.8 | REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX | Genes involved in Degradation of the extracellular matrix |
| 0.0 | 0.4 | REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS | Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins |
| 0.0 | 0.7 | REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS | Genes involved in Extrinsic Pathway for Apoptosis |
| 0.0 | 0.3 | REACTOME PECAM1 INTERACTIONS | Genes involved in PECAM1 interactions |
| 0.0 | 0.4 | REACTOME THE ACTIVATION OF ARYLSULFATASES | Genes involved in The activation of arylsulfatases |
| 0.0 | 0.4 | REACTOME POL SWITCHING | Genes involved in Polymerase switching |
| 0.0 | 0.3 | REACTOME CALNEXIN CALRETICULIN CYCLE | Genes involved in Calnexin/calreticulin cycle |
| 0.0 | 0.3 | REACTOME ETHANOL OXIDATION | Genes involved in Ethanol oxidation |
| 0.0 | 0.6 | REACTOME PROLACTIN RECEPTOR SIGNALING | Genes involved in Prolactin receptor signaling |
| 0.0 | 0.6 | REACTOME PRE NOTCH PROCESSING IN GOLGI | Genes involved in Pre-NOTCH Processing in Golgi |
| 0.0 | 1.3 | REACTOME CLEAVAGE OF GROWING TRANSCRIPT IN THE TERMINATION REGION | Genes involved in Cleavage of Growing Transcript in the Termination Region |
| 0.0 | 0.3 | REACTOME G2 M DNA DAMAGE CHECKPOINT | Genes involved in G2/M DNA damage checkpoint |
| 0.0 | 0.2 | REACTOME SIGNALING BY SCF KIT | Genes involved in Signaling by SCF-KIT |
| 0.0 | 0.5 | REACTOME G1 S SPECIFIC TRANSCRIPTION | Genes involved in G1/S-Specific Transcription |
| 0.0 | 0.5 | REACTOME INSULIN SYNTHESIS AND PROCESSING | Genes involved in Insulin Synthesis and Processing |
| 0.0 | 0.6 | REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS | Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers |
| 0.0 | 0.6 | REACTOME KINESINS | Genes involved in Kinesins |
| 0.0 | 0.3 | REACTOME THE NLRP3 INFLAMMASOME | Genes involved in The NLRP3 inflammasome |
| 0.0 | 0.8 | REACTOME GLYCOSPHINGOLIPID METABOLISM | Genes involved in Glycosphingolipid metabolism |
| 0.0 | 0.4 | REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM | Genes involved in Branched-chain amino acid catabolism |
| 0.0 | 0.1 | REACTOME DOWNSTREAM SIGNAL TRANSDUCTION | Genes involved in Downstream signal transduction |
| 0.0 | 0.6 | REACTOME LYSOSOME VESICLE BIOGENESIS | Genes involved in Lysosome Vesicle Biogenesis |
| 0.0 | 0.4 | REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION | Genes involved in Pre-NOTCH Transcription and Translation |
| 0.0 | 0.2 | REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE | Genes involved in Reversible Hydration of Carbon Dioxide |
| 0.0 | 0.2 | REACTOME CTNNB1 PHOSPHORYLATION CASCADE | Genes involved in Beta-catenin phosphorylation cascade |
| 0.0 | 0.2 | REACTOME G ALPHA Z SIGNALLING EVENTS | Genes involved in G alpha (z) signalling events |
| 0.0 | 0.3 | REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE | Genes involved in mRNA Decay by 5' to 3' Exoribonuclease |
| 0.0 | 0.4 | REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR | Genes involved in Signaling by constitutively active EGFR |
| 0.0 | 1.1 | REACTOME NRAGE SIGNALS DEATH THROUGH JNK | Genes involved in NRAGE signals death through JNK |
| 0.0 | 0.3 | REACTOME EICOSANOID LIGAND BINDING RECEPTORS | Genes involved in Eicosanoid ligand-binding receptors |
| 0.0 | 0.5 | REACTOME RNA POL I TRANSCRIPTION INITIATION | Genes involved in RNA Polymerase I Transcription Initiation |
| 0.0 | 0.8 | REACTOME MYOGENESIS | Genes involved in Myogenesis |
| 0.0 | 0.1 | REACTOME ACTIVATION OF NF KAPPAB IN B CELLS | Genes involved in Activation of NF-kappaB in B Cells |