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Inflammatory response time course, HUVEC (Wada, 2009)

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Results for SRY

Z-value: 0.93

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Transcription factors associated with SRY

Gene Symbol Gene ID Gene Info
SRY
ENSG00000184895.8 SRY

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SRYhg38_v1_chrY_-_2787676_2787687-0.213.1e-01Click!

Activity profile of SRY motif

Sorted Z-values of SRY motif

Network of associatons between targets according to the STRING database.

First level regulatory network of SRY

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr4_+_41612892 4.59 ENST00000509454.5
ENST00000396595.7
ENST00000381753.8
LIMCH1
LIM and calponin homology domains 1
chr4_+_41612702 4.26 ENST00000509277.5
LIMCH1
LIM and calponin homology domains 1
chr5_-_111756245 3.55 ENST00000447165.6
NREP
neuronal regeneration related protein
chr9_-_14314132 2.89 ENST00000380953.6
NFIB
nuclear factor I B
chr9_-_14314567 2.55 ENST00000397579.6
NFIB
nuclear factor I B
chr9_-_14314519 2.45 ENST00000397581.6
NFIB
nuclear factor I B
chr1_+_61081728 2.39 ENST00000371189.8
NFIA
nuclear factor I A
chr1_+_84164370 2.36 ENST00000446538.5
ENST00000610703.4
ENST00000370682.7
ENST00000394838.6
ENST00000432111.5
PRKACB
protein kinase cAMP-activated catalytic subunit beta
chr1_+_84164962 2.24 ENST00000614872.4
ENST00000394839.6
PRKACB
protein kinase cAMP-activated catalytic subunit beta
chr2_-_156342348 2.22 ENST00000409572.5
NR4A2
nuclear receptor subfamily 4 group A member 2
chr14_-_91946989 2.21 ENST00000556154.5
FBLN5
fibulin 5
chr14_+_52553273 2.09 ENST00000542169.6
ENST00000555622.1
GPR137C
G protein-coupled receptor 137C
chr17_-_69141878 1.98 ENST00000590645.1
ENST00000284425.7
ABCA6
ATP binding cassette subfamily A member 6
chr1_+_61082553 1.90 ENST00000403491.8
ENST00000371187.7
NFIA
nuclear factor I A
chr14_-_91947654 1.90 ENST00000342058.9
FBLN5
fibulin 5
chr18_+_23135452 1.78 ENST00000580153.5
ENST00000256925.12
CABLES1
Cdk5 and Abl enzyme substrate 1
chr9_-_14313642 1.72 ENST00000637742.1
NFIB
nuclear factor I B
chr9_+_2159672 1.71 ENST00000634343.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr15_-_59372863 1.64 ENST00000288235.9
MYO1E
myosin IE
chr14_-_91947383 1.64 ENST00000267620.14
FBLN5
fibulin 5
chr17_-_64390852 1.62 ENST00000563924.6
PECAM1
platelet and endothelial cell adhesion molecule 1
chr18_+_75210789 1.47 ENST00000580243.3
TSHZ1
teashirt zinc finger homeobox 1
chr18_-_55635948 1.44 ENST00000565124.4
ENST00000398339.5
TCF4
transcription factor 4
chr1_+_164559739 1.43 ENST00000627490.2
PBX1
PBX homeobox 1
chr9_-_127847117 1.42 ENST00000480266.5
ENG
endoglin
chr18_+_75210755 1.41 ENST00000322038.5
TSHZ1
teashirt zinc finger homeobox 1
chr9_+_2110354 1.35 ENST00000634772.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr1_+_185734362 1.32 ENST00000271588.9
HMCN1
hemicentin 1
chr15_-_70702273 1.31 ENST00000558758.5
ENST00000379983.6
ENST00000560441.5
UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr16_+_30395400 1.25 ENST00000320159.2
ENST00000613509.2
ZNF48
zinc finger protein 48
chr2_-_208254232 1.19 ENST00000415913.5
ENST00000415282.5
ENST00000446179.5
IDH1
isocitrate dehydrogenase (NADP(+)) 1
chr14_-_22819721 1.17 ENST00000554517.5
ENST00000285850.11
ENST00000397529.6
ENST00000555702.5
SLC7A7
solute carrier family 7 member 7
chr7_-_32892015 1.10 ENST00000452926.1
KBTBD2
kelch repeat and BTB domain containing 2
chr18_+_3448456 1.08 ENST00000549780.5
TGIF1
TGFB induced factor homeobox 1
chr9_-_14313843 1.06 ENST00000636063.1
ENST00000380921.3
ENST00000622520.1
ENST00000380959.7
NFIB
nuclear factor I B
chr14_+_52552830 1.03 ENST00000321662.11
GPR137C
G protein-coupled receptor 137C
chr14_-_89417148 0.98 ENST00000557258.6
FOXN3
forkhead box N3
chrX_+_28587411 0.96 ENST00000378993.6
IL1RAPL1
interleukin 1 receptor accessory protein like 1
chr1_+_33256479 0.94 ENST00000539719.6
ENST00000483388.5
ZNF362
zinc finger protein 362
chr18_-_55302613 0.93 ENST00000561831.7
TCF4
transcription factor 4
chr3_-_142149515 0.93 ENST00000475734.5
ENST00000467072.5
ENST00000489671.6
TFDP2
transcription factor Dp-2
chr18_-_55589836 0.88 ENST00000537578.5
ENST00000564403.6
TCF4
transcription factor 4
chr18_-_55589770 0.87 ENST00000565018.6
ENST00000636400.2
TCF4
transcription factor 4
chr18_-_55321986 0.86 ENST00000570287.6
TCF4
transcription factor 4
chr14_+_91114431 0.85 ENST00000428926.6
ENST00000517362.5
DGLUCY
D-glutamate cyclase
chrX_+_85244075 0.84 ENST00000276123.7
ZNF711
zinc finger protein 711
chrX_+_85244032 0.83 ENST00000373165.7
ZNF711
zinc finger protein 711
chr14_+_91114667 0.81 ENST00000523894.5
ENST00000522322.5
ENST00000523771.5
DGLUCY
D-glutamate cyclase
chr18_-_55321640 0.80 ENST00000637169.2
TCF4
transcription factor 4
chr18_-_55589795 0.80 ENST00000568740.5
ENST00000629387.2
TCF4
transcription factor 4
chr3_+_28348695 0.79 ENST00000383768.7
ZCWPW2
zinc finger CW-type and PWWP domain containing 2
chr17_+_59331633 0.77 ENST00000312655.9
YPEL2
yippee like 2
chr4_-_151325488 0.77 ENST00000604030.7
SH3D19
SH3 domain containing 19
chr14_+_91114364 0.76 ENST00000518868.5
DGLUCY
D-glutamate cyclase
chr12_-_102197827 0.76 ENST00000329406.5
PMCH
pro-melanin concentrating hormone
chr2_-_159616442 0.75 ENST00000541068.6
ENST00000392783.7
ENST00000392782.5
BAZ2B
bromodomain adjacent to zinc finger domain 2B
chr14_-_52552493 0.74 ENST00000281741.9
ENST00000557374.1
TXNDC16
thioredoxin domain containing 16
chr1_+_96722628 0.74 ENST00000675401.1
PTBP2
polypyrimidine tract binding protein 2
chr2_-_191847068 0.74 ENST00000304141.5
CAVIN2
caveolae associated protein 2
chr3_-_28348805 0.73 ENST00000457172.5
ENST00000479665.6
AZI2
5-azacytidine induced 2
chr18_-_55322215 0.72 ENST00000457482.7
TCF4
transcription factor 4
chr21_-_38498415 0.72 ENST00000398905.5
ENST00000398907.5
ENST00000453032.6
ENST00000288319.12
ERG
ETS transcription factor ERG
chr9_-_71768386 0.70 ENST00000377066.9
ENST00000377044.9
CEMIP2
cell migration inducing hyaluronidase 2
chr3_-_112641292 0.70 ENST00000439685.6
CCDC80
coiled-coil domain containing 80
chr2_+_108588286 0.69 ENST00000332345.10
LIMS1
LIM zinc finger domain containing 1
chr13_-_74133892 0.68 ENST00000377669.7
KLF12
Kruppel like factor 12
chr16_-_15643024 0.67 ENST00000540441.6
MARF1
meiosis regulator and mRNA stability factor 1
chr1_+_84164684 0.67 ENST00000370680.5
PRKACB
protein kinase cAMP-activated catalytic subunit beta
chr6_+_156777366 0.66 ENST00000636930.2
ARID1B
AT-rich interaction domain 1B
chr1_+_66332004 0.66 ENST00000371045.9
ENST00000531025.5
ENST00000526197.5
PDE4B
phosphodiesterase 4B
chr19_+_10602436 0.65 ENST00000590382.5
ENST00000407327.8
SLC44A2
solute carrier family 44 member 2
chr14_-_50561119 0.60 ENST00000555216.5
MAP4K5
mitogen-activated protein kinase kinase kinase kinase 5
chr11_-_10808304 0.58 ENST00000532082.6
EIF4G2
eukaryotic translation initiation factor 4 gamma 2
chr2_+_74002685 0.58 ENST00000305799.8
TET3
tet methylcytosine dioxygenase 3
chr22_+_19723525 0.58 ENST00000366425.4
GP1BB
glycoprotein Ib platelet subunit beta
chr20_-_63951122 0.57 ENST00000369908.9
UCKL1
uridine-cytidine kinase 1 like 1
chr11_+_114060204 0.56 ENST00000683318.1
ZBTB16
zinc finger and BTB domain containing 16
chr5_+_139341875 0.56 ENST00000511706.5
PAIP2
poly(A) binding protein interacting protein 2
chr19_+_13023958 0.56 ENST00000587760.5
ENST00000585575.5
NFIX
nuclear factor I X
chr12_-_85836372 0.56 ENST00000361228.5
RASSF9
Ras association domain family member 9
chr10_-_14572123 0.54 ENST00000378465.7
ENST00000452706.6
ENST00000622567.4
ENST00000378458.6
FAM107B
family with sequence similarity 107 member B
chr6_+_138773747 0.54 ENST00000617445.5
CCDC28A
coiled-coil domain containing 28A
chr4_+_169660062 0.52 ENST00000507875.5
ENST00000613795.4
CLCN3
chloride voltage-gated channel 3
chr3_-_28348924 0.51 ENST00000414162.5
ENST00000420543.6
AZI2
5-azacytidine induced 2
chr8_+_69492793 0.50 ENST00000616868.1
ENST00000419716.7
ENST00000402687.9
SULF1
sulfatase 1
chr3_+_25428233 0.49 ENST00000437042.6
ENST00000330688.9
RARB
retinoic acid receptor beta
chr18_-_55351977 0.49 ENST00000643689.1
TCF4
transcription factor 4
chr7_-_32891744 0.49 ENST00000304056.9
KBTBD2
kelch repeat and BTB domain containing 2
chr9_+_27109393 0.48 ENST00000406359.8
TEK
TEK receptor tyrosine kinase
chr20_+_325536 0.48 ENST00000342665.5
SOX12
SRY-box transcription factor 12
chr3_+_124384513 0.47 ENST00000682540.1
ENST00000522553.6
ENST00000682695.1
ENST00000682674.1
ENST00000684382.1
KALRN
kalirin RhoGEF kinase
chr9_-_122227525 0.47 ENST00000373755.6
ENST00000373754.6
LHX6
LIM homeobox 6
chr8_-_81483226 0.46 ENST00000256104.5
FABP4
fatty acid binding protein 4
chr15_-_34318761 0.45 ENST00000290209.9
SLC12A6
solute carrier family 12 member 6
chr5_+_139308095 0.44 ENST00000515833.2
MATR3
matrin 3
chr15_-_70097874 0.43 ENST00000557997.5
ENST00000317509.12
ENST00000451782.7
ENST00000627388.2
TLE3
TLE family member 3, transcriptional corepressor
chr11_-_82997477 0.42 ENST00000534301.5
RAB30
RAB30, member RAS oncogene family
chr11_+_128694052 0.42 ENST00000527786.7
ENST00000534087.3
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr18_+_3451647 0.42 ENST00000345133.9
ENST00000330513.10
ENST00000549546.5
TGIF1
TGFB induced factor homeobox 1
chr12_+_59664677 0.41 ENST00000548610.5
SLC16A7
solute carrier family 16 member 7
chr2_+_108588453 0.40 ENST00000393310.5
LIMS1
LIM zinc finger domain containing 1
chr19_+_13024917 0.39 ENST00000587260.1
NFIX
nuclear factor I X
chrX_-_19670983 0.39 ENST00000379716.5
SH3KBP1
SH3 domain containing kinase binding protein 1
chr18_+_3451585 0.38 ENST00000551541.5
TGIF1
TGFB induced factor homeobox 1
chr7_-_27180230 0.38 ENST00000396344.4
HOXA10
homeobox A10
chr3_-_28348629 0.38 ENST00000334100.10
AZI2
5-azacytidine induced 2
chr11_+_128693887 0.37 ENST00000281428.12
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr16_-_1782526 0.37 ENST00000566339.6
SPSB3
splA/ryanodine receptor domain and SOCS box containing 3
chr7_+_80638633 0.37 ENST00000447544.7
ENST00000482059.6
CD36
CD36 molecule
chrX_+_123961696 0.35 ENST00000371145.8
ENST00000371157.7
ENST00000371144.7
STAG2
stromal antigen 2
chr3_+_189789672 0.35 ENST00000434928.5
TP63
tumor protein p63
chr2_+_69013379 0.35 ENST00000409349.7
ANTXR1
ANTXR cell adhesion molecule 1
chr14_+_22516273 0.35 ENST00000390510.1
TRAJ27
T cell receptor alpha joining 27
chr20_-_44521989 0.35 ENST00000342374.5
ENST00000255175.5
SERINC3
serine incorporator 3
chr10_+_113125536 0.34 ENST00000349937.7
TCF7L2
transcription factor 7 like 2
chr5_-_11589019 0.34 ENST00000511377.5
CTNND2
catenin delta 2
chr19_-_45768627 0.34 ENST00000560160.1
SIX5
SIX homeobox 5
chrX_+_15507302 0.34 ENST00000342014.6
BMX
BMX non-receptor tyrosine kinase
chr1_-_52552994 0.33 ENST00000355809.4
ENST00000528642.5
ENST00000470626.1
ENST00000257177.9
ENST00000371544.7
TUT4
terminal uridylyl transferase 4
chr7_+_80638510 0.33 ENST00000433696.6
ENST00000538969.5
ENST00000544133.5
CD36
CD36 molecule
chr6_+_156777882 0.33 ENST00000350026.10
ENST00000647938.1
ENST00000674298.1
ARID1B
AT-rich interaction domain 1B
chr13_-_40666600 0.33 ENST00000379561.6
FOXO1
forkhead box O1
chr5_+_139342442 0.33 ENST00000394795.6
ENST00000510080.1
PAIP2
poly(A) binding protein interacting protein 2
chr14_-_73027077 0.32 ENST00000553891.5
ENST00000556143.6
ZFYVE1
zinc finger FYVE-type containing 1
chr5_+_141177790 0.32 ENST00000239444.4
ENST00000623995.1
PCDHB8
ENSG00000279472.1
protocadherin beta 8
novel transcript
chr8_+_66493556 0.31 ENST00000305454.8
ENST00000522977.5
ENST00000480005.1
VXN
vexin
chr2_+_190408324 0.31 ENST00000417958.5
ENST00000432036.5
ENST00000392328.6
MFSD6
major facilitator superfamily domain containing 6
chrX_-_24672654 0.31 ENST00000379145.5
PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr7_+_134866831 0.30 ENST00000435928.1
CALD1
caldesmon 1
chr10_-_125160499 0.30 ENST00000494626.6
ENST00000337195.9
CTBP2
C-terminal binding protein 2
chr9_-_95509241 0.29 ENST00000331920.11
PTCH1
patched 1
chr14_-_73027117 0.29 ENST00000318876.9
ZFYVE1
zinc finger FYVE-type containing 1
chr2_-_207165923 0.29 ENST00000309446.11
KLF7
Kruppel like factor 7
chr20_-_3781440 0.29 ENST00000379756.3
SPEF1
sperm flagellar 1
chr3_+_179148341 0.29 ENST00000263967.4
PIK3CA
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
chrX_+_101488044 0.28 ENST00000423738.4
ARMCX4
armadillo repeat containing X-linked 4
chr10_+_110207587 0.28 ENST00000332674.9
ENST00000453116.5
MXI1
MAX interactor 1, dimerization protein
chr18_+_11851404 0.28 ENST00000526991.3
CHMP1B
charged multivesicular body protein 1B
chr18_+_21363593 0.28 ENST00000580732.6
GREB1L
GREB1 like retinoic acid receptor coactivator
chr7_+_143288215 0.28 ENST00000619992.4
ENST00000310447.10
CASP2
caspase 2
chr1_-_151146643 0.26 ENST00000613223.1
SEMA6C
semaphorin 6C
chr2_+_86720282 0.26 ENST00000283632.5
RMND5A
required for meiotic nuclear division 5 homolog A
chr17_-_42276341 0.25 ENST00000293328.8
STAT5B
signal transducer and activator of transcription 5B
chr1_+_206834347 0.25 ENST00000340758.7
IL19
interleukin 19
chr10_+_72893734 0.24 ENST00000334011.10
OIT3
oncoprotein induced transcript 3
chr5_+_87267792 0.24 ENST00000274376.11
RASA1
RAS p21 protein activator 1
chr17_-_59151794 0.24 ENST00000584089.1
SKA2
spindle and kinetochore associated complex subunit 2
chr7_+_128758947 0.24 ENST00000493278.1
CALU
calumenin
chr11_-_118225002 0.24 ENST00000356289.10
ENST00000526620.5
JAML
junction adhesion molecule like
chr2_+_27442421 0.24 ENST00000407293.5
KRTCAP3
keratinocyte associated protein 3
chr2_+_9961165 0.23 ENST00000405379.6
GRHL1
grainyhead like transcription factor 1
chr10_+_110225955 0.23 ENST00000239007.11
MXI1
MAX interactor 1, dimerization protein
chr8_-_71547626 0.23 ENST00000647540.1
ENST00000644229.1
EYA1
EYA transcriptional coactivator and phosphatase 1
chr19_+_13795434 0.22 ENST00000254323.6
ZSWIM4
zinc finger SWIM-type containing 4
chr16_+_28846674 0.22 ENST00000322610.12
SH2B1
SH2B adaptor protein 1
chr20_+_10435283 0.22 ENST00000334534.10
SLX4IP
SLX4 interacting protein
chr9_+_27109135 0.22 ENST00000519097.5
ENST00000615002.4
TEK
TEK receptor tyrosine kinase
chr10_-_48274567 0.22 ENST00000636244.1
ENST00000374201.8
FRMPD2
FERM and PDZ domain containing 2
chr15_-_51971740 0.22 ENST00000315141.5
ENST00000299601.10
LEO1
LEO1 homolog, Paf1/RNA polymerase II complex component
chr1_+_226063466 0.21 ENST00000666609.1
ENST00000661429.1
H3-3A
H3.3 histone A
chr5_+_141364153 0.21 ENST00000518069.2
PCDHGA5
protocadherin gamma subfamily A, 5
chr7_-_19773569 0.21 ENST00000422233.5
ENST00000433641.5
ENST00000405844.6
TMEM196
transmembrane protein 196
chr14_+_58427425 0.21 ENST00000619722.5
ENST00000423743.7
KIAA0586
KIAA0586
chr6_-_31684040 0.20 ENST00000375863.7
LY6G5C
lymphocyte antigen 6 family member G5C
chr5_+_140868945 0.20 ENST00000398640.7
PCDHA11
protocadherin alpha 11
chr1_-_151146611 0.20 ENST00000341697.7
ENST00000368914.8
SEMA6C
semaphorin 6C
chr5_+_138338256 0.20 ENST00000513056.5
ENST00000239906.10
ENST00000511276.1
FAM53C
family with sequence similarity 53 member C
chr6_-_52244500 0.20 ENST00000336123.5
IL17F
interleukin 17F
chr12_-_8662881 0.20 ENST00000433590.6
MFAP5
microfibril associated protein 5
chrX_-_16869840 0.20 ENST00000380084.8
RBBP7
RB binding protein 7, chromatin remodeling factor
chr14_+_58427385 0.19 ENST00000354386.10
ENST00000619416.4
KIAA0586
KIAA0586
chr12_-_27971970 0.19 ENST00000395872.5
ENST00000201015.8
PTHLH
parathyroid hormone like hormone
chr12_-_75209422 0.19 ENST00000393288.2
ENST00000540018.5
KCNC2
potassium voltage-gated channel subfamily C member 2
chr5_+_126777112 0.19 ENST00000261366.10
ENST00000492190.5
ENST00000395354.1
LMNB1
lamin B1
chr8_+_66493514 0.19 ENST00000521495.5
VXN
vexin
chr9_-_39239174 0.18 ENST00000358144.6
CNTNAP3
contactin associated protein family member 3
chr5_+_143812161 0.18 ENST00000289448.4
HMHB1
histocompatibility minor HB-1
chr5_+_141364231 0.17 ENST00000611914.1
PCDHGA5
protocadherin gamma subfamily A, 5
chr16_-_3880678 0.17 ENST00000262367.10
CREBBP
CREB binding protein
chr9_+_27109200 0.16 ENST00000380036.10
TEK
TEK receptor tyrosine kinase
chr19_-_45769204 0.16 ENST00000317578.7
SIX5
SIX homeobox 5
chr11_-_82997394 0.15 ENST00000525117.5
ENST00000532548.5
RAB30
RAB30, member RAS oncogene family
chr14_+_91114388 0.14 ENST00000519019.5
ENST00000523816.5
ENST00000517518.5
DGLUCY
D-glutamate cyclase
chr7_+_29479712 0.14 ENST00000412711.6
CHN2
chimerin 2
chr12_-_75209701 0.14 ENST00000350228.6
ENST00000298972.5
KCNC2
potassium voltage-gated channel subfamily C member 2
chr4_-_110198650 0.14 ENST00000394607.7
ELOVL6
ELOVL fatty acid elongase 6
chr20_-_62427528 0.14 ENST00000252998.2
RBBP8NL
RBBP8 N-terminal like
chr4_-_110198579 0.14 ENST00000302274.8
ELOVL6
ELOVL fatty acid elongase 6
chr12_-_7503841 0.13 ENST00000359156.8
CD163
CD163 molecule
chr5_+_177133005 0.13 ENST00000510954.5
ENST00000354179.8
NSD1
nuclear receptor binding SET domain protein 1
chr11_-_44950151 0.13 ENST00000533940.5
ENST00000533937.1
TP53I11
tumor protein p53 inducible protein 11
chr2_+_161231078 0.12 ENST00000439442.1
TANK
TRAF family member associated NFKB activator
chr22_+_39901075 0.12 ENST00000344138.9
GRAP2
GRB2 related adaptor protein 2
chrX_-_40096190 0.12 ENST00000679513.1
BCOR
BCL6 corepressor
chr14_+_74348440 0.11 ENST00000256362.5
VRTN
vertebrae development associated
chr12_-_91058016 0.11 ENST00000266719.4
KERA
keratocan
chr6_+_83853576 0.11 ENST00000369687.2
RIPPLY2
ripply transcriptional repressor 2
chr8_-_42501224 0.11 ENST00000520262.6
ENST00000517366.1
SLC20A2
solute carrier family 20 member 2
chr16_+_3654683 0.11 ENST00000246949.10
DNASE1
deoxyribonuclease 1
chr7_+_143959927 0.11 ENST00000624504.1
OR2F1
olfactory receptor family 2 subfamily F member 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 10.7 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.8 5.3 GO:0097338 response to clozapine(GO:0097338)
0.7 2.2 GO:0021986 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.5 2.9 GO:0060023 soft palate development(GO:0060023)
0.5 5.7 GO:0048251 elastic fiber assembly(GO:0048251)
0.5 1.4 GO:0001300 chronological cell aging(GO:0001300)
0.4 1.6 GO:0072011 diapedesis(GO:0050904) glomerular endothelium development(GO:0072011)
0.4 1.2 GO:0006097 glyoxylate cycle(GO:0006097)
0.3 1.6 GO:0044565 dendritic cell proliferation(GO:0044565)
0.2 1.6 GO:0035166 post-embryonic hemopoiesis(GO:0035166)
0.2 0.6 GO:0044725 chromatin reprogramming in the zygote(GO:0044725)
0.2 0.5 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.2 1.2 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.1 1.0 GO:0097026 dendritic cell dendrite assembly(GO:0097026)
0.1 0.7 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199) positive regulation of blood vessel remodeling(GO:2000504)
0.1 3.8 GO:0072189 ureter development(GO:0072189)
0.1 0.9 GO:0048014 Tie signaling pathway(GO:0048014)
0.1 0.4 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.1 0.5 GO:0048388 endosomal lumen acidification(GO:0048388)
0.1 0.6 GO:0051138 positive regulation of NK T cell differentiation(GO:0051138)
0.1 0.3 GO:1902617 response to fluoride(GO:1902617)
0.1 0.4 GO:1901202 negative regulation of extracellular matrix assembly(GO:1901202)
0.1 0.7 GO:0070543 response to linoleic acid(GO:0070543) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.1 0.3 GO:0010157 response to chlorate(GO:0010157)
0.1 0.3 GO:2000653 regulation of genetic imprinting(GO:2000653)
0.1 0.5 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.1 0.5 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.1 0.3 GO:0001865 NK T cell differentiation(GO:0001865)
0.1 0.2 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.1 0.4 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.1 0.7 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.2 GO:0045423 regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045423)
0.0 1.5 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.5 GO:0046959 habituation(GO:0046959) negative regulation of growth hormone secretion(GO:0060125)
0.0 0.3 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.0 0.3 GO:0009597 detection of virus(GO:0009597)
0.0 0.2 GO:0045588 positive regulation of gamma-delta T cell differentiation(GO:0045588)
0.0 0.2 GO:0035696 monocyte extravasation(GO:0035696)
0.0 1.0 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.2 GO:0010286 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.0 0.6 GO:0015871 choline transport(GO:0015871)
0.0 0.8 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.8 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.1 GO:1902723 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.0 0.1 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.0 0.4 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.3 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.8 GO:0050872 white fat cell differentiation(GO:0050872)
0.0 0.3 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 8.3 GO:0065004 protein-DNA complex assembly(GO:0065004)
0.0 0.1 GO:0035992 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.0 0.5 GO:0021800 cerebral cortex tangential migration(GO:0021800)
0.0 1.1 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894)
0.0 0.1 GO:0014724 regulation of twitch skeletal muscle contraction(GO:0014724)
0.0 0.7 GO:0097320 membrane tubulation(GO:0097320)
0.0 0.3 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.1 GO:0045013 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.0 8.6 GO:0031032 actomyosin structure organization(GO:0031032)
0.0 0.9 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.3 GO:1904903 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.0 0.6 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.9 GO:1900271 regulation of long-term synaptic potentiation(GO:1900271)
0.0 0.1 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.0 0.1 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.2 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
0.0 0.1 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.1 GO:0002399 MHC class II protein complex assembly(GO:0002399)
0.0 0.2 GO:0042226 interleukin-6 biosynthetic process(GO:0042226)
0.0 0.0 GO:0005988 lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989)
0.0 0.8 GO:0033119 negative regulation of RNA splicing(GO:0033119)
0.0 0.7 GO:0045920 negative regulation of exocytosis(GO:0045920)
0.0 0.5 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.1 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 0.5 GO:0007143 female meiotic division(GO:0007143)
0.0 1.3 GO:1901222 regulation of NIK/NF-kappaB signaling(GO:1901222)
0.0 0.2 GO:0033523 histone H2B ubiquitination(GO:0033523)
0.0 0.4 GO:0060065 uterus development(GO:0060065)
0.0 0.0 GO:1902688 regulation of NAD metabolic process(GO:1902688)
0.0 2.0 GO:0007286 spermatid development(GO:0007286)
0.0 0.1 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 5.7 GO:0071953 elastic fiber(GO:0071953)
0.5 1.4 GO:0072563 endothelial microparticle(GO:0072563)
0.4 10.5 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.2 5.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.2 0.6 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.1 3.7 GO:0016514 SWI/SNF complex(GO:0016514)
0.1 0.3 GO:0034657 GID complex(GO:0034657)
0.1 0.6 GO:0001940 male pronucleus(GO:0001940)
0.1 0.3 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.1 2.3 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 7.9 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.3 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.6 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.0 0.7 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.7 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.2 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.3 GO:0030478 actin cap(GO:0030478)
0.0 0.3 GO:0097470 ribbon synapse(GO:0097470)
0.0 0.2 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.2 GO:0005638 lamin filament(GO:0005638)
0.0 1.2 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 1.7 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 1.6 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.3 GO:0000815 ESCRT III complex(GO:0000815)
0.0 2.9 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.1 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.2 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450) (R)-2-hydroxyglutarate dehydrogenase activity(GO:0051990)
0.4 7.8 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.3 5.3 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.2 1.4 GO:0005534 galactose binding(GO:0005534)
0.1 0.4 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.1 0.5 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 0.6 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 0.5 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 2.5 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 0.7 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.1 1.9 GO:0070410 co-SMAD binding(GO:0070410)
0.1 0.6 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.1 1.2 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.1 0.3 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 1.0 GO:0019966 interleukin-1 binding(GO:0019966)
0.1 0.3 GO:0097108 smoothened binding(GO:0005119) hedgehog family protein binding(GO:0097108)
0.1 0.1 GO:0004803 transposase activity(GO:0004803)
0.0 3.7 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.3 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 0.6 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 16.6 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.5 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.2 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.6 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 0.6 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.3 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.3 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.8 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 4.7 GO:0005178 integrin binding(GO:0005178)
0.0 0.1 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.1 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.0 0.1 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.7 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.3 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.8 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.3 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.7 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 2.0 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.0 0.4 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.3 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 0.0 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.6 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.7 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.3 GO:0005523 tropomyosin binding(GO:0005523)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 15.2 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 5.8 PID IL3 PATHWAY IL3-mediated signaling events
0.1 8.4 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 3.4 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 1.4 PID ALK1 PATHWAY ALK1 signaling events
0.0 1.6 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.5 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.5 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 5.3 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.5 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.4 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.4 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.4 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 1.1 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.9 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.4 PID IL23 PATHWAY IL23-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 10.7 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.2 5.7 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 1.6 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.1 7.0 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 2.0 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.6 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 1.1 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.2 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 1.2 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 1.9 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.4 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 1.0 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 1.2 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 1.8 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.5 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.4 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 1.9 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.6 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events